peptide-cutter/expasy_rules.json

A library for digesting amino acid sequences using rules from Expasy

{
    "arg-c":         "R",
    "asp-n":         "\\w(?=D)",
    "bnps-skatole" : "W",
    "caspase 1":     "(?<=[FWYL]\\w[HAT])D(?=[^PEDQKR])",
    "caspase 2":     "(?<=DVA)D(?=[^PEDQKR])",
    "caspase 3":     "(?<=DMQ)D(?=[^PEDQKR])",
    "caspase 4":     "(?<=LE[HV])D(?=[^PEDQKR])",
    "caspase 5":     "(?<=[LW]EH)D",
    "caspase 6":     "(?<=VE[HI])D(?=[^PEDQKR])",
    "caspase 7":     "(?<=DEV)D(?=[^PEDQKR])",
    "caspase 8":     "(?<=[IL]ET)D(?=[^PEDQKR])",
    "caspase 9":     "(?<=LEH)D",
    "caspase 10":    "(?<=IEA)D",
    "chymotrypsin high specificity" : "([FY](?=[^P]))|(W(?=[^MP]))",
    "chymotrypsin low specificity":
        "([FLY](?=[^P]))|(W(?=[^MP]))|(M(?=[^PY]))|(H(?=[^DMPW]))",
    "clostripain":   "R",
    "cnbr":          "M",
    "enterokinase":  "(?<=[DE]{3})K",
    "factor xa":     "(?<=[AFGILTVM][DE]G)R",
    "formic acid":   "D",
    "glutamyl endopeptidase": "E",
    "granzyme b":    "(?<=IEP)D",
    "hydroxylamine": "N(?=G)",
    "iodosobenzoic acid": "W",
    "lysc":          "K",
    "ntcb":          "\\w(?=C)",
    "pepsin ph1.3":  "((?<=[^HKR][^P])[^R](?=[FL][^P]))|((?<=[^HKR][^P])[FL](?=\\w[^P]))",
    "pepsin ph2.0":  "((?<=[^HKR][^P])[^R](?=[FLWY][^P]))|((?<=[^HKR][^P])[FLWY](?=\\w[^P]))",
    "proline endopeptidase": "(?<=[HKR])P(?=[^P])",
    "proteinase k":  "[AEFILTVWY]",
    "staphylococcal peptidase i": "(?<=[^E])E",
    "thermolysin":   "[^DE](?=[AFILMV])",
    "thrombin":      "((?<=G)R(?=G))|((?<=[AFGILTVM][AFGILTVWA]P)R(?=[^DE][^DE]))",
    "trypsin":       "([KR](?=[^P]))|((?<=W)K(?=P))|((?<=M)R(?=P))"
}