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molstar

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A comprehensive macromolecular library.

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/** * Copyright (c) 2018-2025 mol* contributors, licensed under MIT, See LICENSE file for more info. * * @author Alexander Rose <alexander.rose@weirdbyte.de> */ import { ParamDefinition as PD } from '../../../mol-util/param-definition'; import { computeStructureGaussianDensityTexture, computeUnitGaussianDensityTexture, GaussianDensityParams } from './util/gaussian'; import { DirectVolume } from '../../../mol-geo/geometry/direct-volume/direct-volume'; import { ComplexDirectVolumeParams, ComplexDirectVolumeVisual } from '../complex-visual'; import { Mat4, Vec3 } from '../../../mol-math/linear-algebra'; import { eachElement, eachSerialElement, ElementIterator, getElementLoci, getSerialElementLoci } from './util/element'; import { Sphere3D } from '../../../mol-math/geometry'; import { UnitsDirectVolumeParams, UnitsDirectVolumeVisual } from '../units-visual'; function createGaussianDensityVolume(ctx, structure, theme, props, directVolume) { const { webgl } = ctx; if (!webgl) { // gpu gaussian density also needs blendMinMax but there is no fallback here so // we allow it here with the results that there is no group id assignment and // hence no group-based coloring or picking throw new Error('GaussianDensityVolume requires `webgl`'); } const axisOrder = Vec3.create(0, 1, 2); const stats = { min: 0, max: 1, mean: 0.04, sigma: 0.01 }; const create = (directVolume) => { const oldTexture = directVolume ? directVolume.gridTexture.ref.value : undefined; const densityTextureData = computeStructureGaussianDensityTexture(structure, theme.size, props, webgl, oldTexture); const { transform, texture, bbox, gridDim } = densityTextureData; const unitToCartn = Mat4.mul(Mat4(), transform, Mat4.fromScaling(Mat4(), gridDim)); const cellDim = Mat4.getScaling(Vec3(), transform); const vol = DirectVolume.create(bbox, gridDim, transform, unitToCartn, cellDim, texture, stats, true, axisOrder, 'byte', directVolume); const sphere = Sphere3D.expand(Sphere3D(), structure.boundary.sphere, densityTextureData.maxRadius); vol.setBoundingSphere(sphere); return vol; }; const vol = create(directVolume); vol.meta.reset = () => { create(vol); }; return vol; } export const GaussianDensityVolumeParams = { ...ComplexDirectVolumeParams, ...GaussianDensityParams, ignoreHydrogens: PD.Boolean(false), ignoreHydrogensVariant: PD.Select('all', PD.arrayToOptions(['all', 'non-polar'])), includeParent: PD.Boolean(false, { isHidden: true }), }; export function GaussianDensityVolumeVisual(materialId) { return ComplexDirectVolumeVisual({ defaultProps: PD.getDefaultValues(GaussianDensityVolumeParams), createGeometry: createGaussianDensityVolume, createLocationIterator: ElementIterator.fromStructure, getLoci: getSerialElementLoci, eachLocation: eachSerialElement, setUpdateState: (state, newProps, currentProps) => { if (newProps.resolution !== currentProps.resolution) state.createGeometry = true; if (newProps.radiusOffset !== currentProps.radiusOffset) state.createGeometry = true; if (newProps.smoothness !== currentProps.smoothness) state.createGeometry = true; if (newProps.ignoreHydrogens !== currentProps.ignoreHydrogens) state.createGeometry = true; if (newProps.ignoreHydrogensVariant !== currentProps.ignoreHydrogensVariant) state.createGeometry = true; if (newProps.traceOnly !== currentProps.traceOnly) state.createGeometry = true; if (newProps.includeParent !== currentProps.includeParent) state.createGeometry = true; }, dispose: (geometry) => { geometry.gridTexture.ref.value.destroy(); } }, materialId); } // function createUnitsGaussianDensityVolume(ctx, unit, structure, theme, props, directVolume) { const { webgl } = ctx; if (!webgl) { // gpu gaussian density also needs blendMinMax but there is no fallback here so // we allow it here with the results that there is no group id assignment and // hence no group-based coloring or picking throw new Error('GaussianDensityVolume requires `webgl`'); } const axisOrder = Vec3.create(0, 1, 2); const stats = { min: 0, max: 1, mean: 0.04, sigma: 0.01 }; const create = (directVolume) => { const oldTexture = directVolume ? directVolume.gridTexture.ref.value : undefined; const densityTextureData = computeUnitGaussianDensityTexture(structure, unit, theme.size, props, webgl, oldTexture); const { transform, texture, bbox, gridDim } = densityTextureData; const unitToCartn = Mat4.mul(Mat4(), transform, Mat4.fromScaling(Mat4(), gridDim)); const cellDim = Mat4.getScaling(Vec3(), transform); const vol = DirectVolume.create(bbox, gridDim, transform, unitToCartn, cellDim, texture, stats, true, axisOrder, 'byte', directVolume); const sphere = Sphere3D.expand(Sphere3D(), unit.boundary.sphere, densityTextureData.maxRadius); vol.setBoundingSphere(sphere); return vol; }; const vol = create(directVolume); vol.meta.reset = () => { create(vol); }; return vol; } export const UnitsGaussianDensityVolumeParams = { ...UnitsDirectVolumeParams, ...GaussianDensityParams, ignoreHydrogens: PD.Boolean(false), ignoreHydrogensVariant: PD.Select('all', PD.arrayToOptions(['all', 'non-polar'])), includeParent: PD.Boolean(false, { isHidden: true }), }; export function UnitsGaussianDensityVolumeVisual(materialId) { return UnitsDirectVolumeVisual({ defaultProps: PD.getDefaultValues(UnitsGaussianDensityVolumeParams), createGeometry: createUnitsGaussianDensityVolume, createLocationIterator: ElementIterator.fromGroup, getLoci: getElementLoci, eachLocation: eachElement, setUpdateState: (state, newProps, currentProps) => { if (newProps.resolution !== currentProps.resolution) state.createGeometry = true; if (newProps.radiusOffset !== currentProps.radiusOffset) state.createGeometry = true; if (newProps.smoothness !== currentProps.smoothness) state.createGeometry = true; if (newProps.ignoreHydrogens !== currentProps.ignoreHydrogens) state.createGeometry = true; if (newProps.ignoreHydrogensVariant !== currentProps.ignoreHydrogensVariant) state.createGeometry = true; if (newProps.traceOnly !== currentProps.traceOnly) state.createGeometry = true; if (newProps.includeParent !== currentProps.includeParent) state.createGeometry = true; }, dispose: (geometry) => { geometry.gridTexture.ref.value.destroy(); } }, materialId); }