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molstar

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A comprehensive macromolecular library.

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/** * Copyright (c) 2020-2024 mol* contributors, licensed under MIT, See LICENSE file for more info. * * @author Alexander Rose <alexander.rose@weirdbyte.de> */ import { ParamDefinition as PD } from '../../../mol-util/param-definition'; import { Unit, StructureElement } from '../../../mol-model/structure'; import { Vec3 } from '../../../mol-math/linear-algebra'; import { arrayEqual } from '../../../mol-util'; import { createLinkLines, EmptyLinkBuilderProps } from './util/link'; import { UnitsLinesParams, UnitsLinesVisual } from '../units-visual'; import { BondType } from '../../../mol-model/structure/model/types'; import { BondIterator, BondLineParams, getIntraBondLoci, eachIntraBond, makeIntraBondIgnoreTest, ignoreBondType, hasUnitVisibleBonds, hasStructureVisibleBonds, getStructureGroupsBondLoci, eachStructureGroupsBond } from './util/bond'; import { Sphere3D } from '../../../mol-math/geometry'; import { Lines } from '../../../mol-geo/geometry/lines/lines'; import { IntAdjacencyGraph } from '../../../mol-math/graph'; import { arrayIntersectionSize } from '../../../mol-util/array'; import { ComplexLinesParams, ComplexLinesVisual } from '../complex-visual'; import { EmptyLocationIterator } from '../../../mol-geo/util/location-iterator'; // avoiding namespace lookup improved performance in Chrome (Aug 2020) const isBondType = BondType.is; function getIntraUnitBondLineBuilderProps(unit, structure, theme, props) { const location = StructureElement.Location.create(structure, unit); const elements = unit.elements; const bonds = unit.bonds; const { edgeCount, a, b, edgeProps, offset } = bonds; const { order: _order, flags: _flags } = edgeProps; const { sizeFactor, aromaticBonds, includeTypes, excludeTypes, multipleBonds } = props; const mbOff = multipleBonds === 'off'; const mbSymmetric = multipleBonds === 'symmetric'; const include = BondType.fromNames(includeTypes); const exclude = BondType.fromNames(excludeTypes); const ignoreComputedAromatic = ignoreBondType(include, exclude, 32 /* BondType.Flag.Computed */); const vRef = Vec3(); const c = unit.conformation; const { elementRingIndices, elementAromaticRingIndices } = unit.rings; const deloTriplets = aromaticBonds ? unit.resonance.delocalizedTriplets : undefined; return { linkCount: edgeCount * 2, referencePosition: (edgeIndex) => { let aI = a[edgeIndex], bI = b[edgeIndex]; const rI = deloTriplets === null || deloTriplets === void 0 ? void 0 : deloTriplets.getThirdElement(aI, bI); if (rI !== undefined) return c.invariantPosition(elements[rI], vRef); if (aI > bI) [aI, bI] = [bI, aI]; if (offset[aI + 1] - offset[aI] === 1) [aI, bI] = [bI, aI]; const aR = elementAromaticRingIndices.get(aI) || elementRingIndices.get(aI); let maxSize = 0; for (let i = offset[aI], il = offset[aI + 1]; i < il; ++i) { const _bI = b[i]; if (_bI !== bI && _bI !== aI) { if (aR) { const _bR = elementAromaticRingIndices.get(_bI) || elementRingIndices.get(_bI); if (!_bR) continue; const size = arrayIntersectionSize(aR, _bR); if (size > maxSize) { maxSize = size; c.invariantPosition(elements[_bI], vRef); } } else { return c.invariantPosition(elements[_bI], vRef); } } } return maxSize > 0 ? vRef : null; }, position: (posA, posB, edgeIndex, _adjust) => { c.invariantPosition(elements[a[edgeIndex]], posA); c.invariantPosition(elements[b[edgeIndex]], posB); }, style: (edgeIndex) => { const o = _order[edgeIndex]; const f = _flags[edgeIndex]; if (isBondType(f, 2 /* BondType.Flag.MetallicCoordination */) || isBondType(f, 4 /* BondType.Flag.HydrogenBond */)) { // show metallic coordinations and hydrogen bonds with dashed lines return 1 /* LinkStyle.Dashed */; } else if (o === 3) { return mbOff ? 0 /* LinkStyle.Solid */ : mbSymmetric ? 4 /* LinkStyle.Triple */ : 5 /* LinkStyle.OffsetTriple */; } else if (aromaticBonds) { const aI = a[edgeIndex], bI = b[edgeIndex]; const aR = elementAromaticRingIndices.get(aI); const bR = elementAromaticRingIndices.get(bI); const arCount = (aR && bR) ? arrayIntersectionSize(aR, bR) : 0; if (isBondType(f, 16 /* BondType.Flag.Aromatic */) || (arCount && !ignoreComputedAromatic)) { if (arCount === 2) { return 8 /* LinkStyle.MirroredAromatic */; } else { return 7 /* LinkStyle.Aromatic */; } } } return (o !== 2 || mbOff) ? 0 /* LinkStyle.Solid */ : mbSymmetric ? 2 /* LinkStyle.Double */ : 3 /* LinkStyle.OffsetDouble */; }, radius: (edgeIndex) => { location.element = elements[a[edgeIndex]]; const sizeA = theme.size.size(location); location.element = elements[b[edgeIndex]]; const sizeB = theme.size.size(location); return Math.min(sizeA, sizeB) * sizeFactor; }, ignore: makeIntraBondIgnoreTest(structure, unit, props) }; } function createIntraUnitBondLines(ctx, unit, structure, theme, props, lines) { if (!Unit.isAtomic(unit)) return Lines.createEmpty(lines); if (!hasUnitVisibleBonds(unit, props)) return Lines.createEmpty(lines); if (!unit.bonds.edgeCount) return Lines.createEmpty(lines); const { child } = structure; const childUnit = child === null || child === void 0 ? void 0 : child.unitMap.get(unit.id); if (child && !childUnit) return Lines.createEmpty(lines); const builderProps = getIntraUnitBondLineBuilderProps(unit, structure, theme, props); const { lines: l, boundingSphere } = createLinkLines(ctx, builderProps, props, lines); if (boundingSphere) { l.setBoundingSphere(boundingSphere); } else if (l.lineCount > 0) { const sphere = Sphere3D.expand(Sphere3D(), (childUnit !== null && childUnit !== void 0 ? childUnit : unit).boundary.sphere, 1 * props.sizeFactor); l.setBoundingSphere(sphere); } return l; } export const IntraUnitBondLineParams = { ...UnitsLinesParams, ...BondLineParams, includeParent: PD.Boolean(false), }; export function IntraUnitBondLineVisual(materialId) { return UnitsLinesVisual({ defaultProps: PD.getDefaultValues(IntraUnitBondLineParams), createGeometry: createIntraUnitBondLines, createLocationIterator: (structureGroup) => BondIterator.fromGroup(structureGroup), getLoci: getIntraBondLoci, eachLocation: eachIntraBond, setUpdateState: (state, newProps, currentProps, newTheme, currentTheme, newStructureGroup, currentStructureGroup) => { state.createGeometry = (newProps.sizeFactor !== currentProps.sizeFactor || newProps.linkScale !== currentProps.linkScale || newProps.linkSpacing !== currentProps.linkSpacing || newProps.aromaticDashCount !== currentProps.aromaticDashCount || newProps.dashCount !== currentProps.dashCount || newProps.ignoreHydrogens !== currentProps.ignoreHydrogens || newProps.ignoreHydrogensVariant !== currentProps.ignoreHydrogensVariant || !arrayEqual(newProps.includeTypes, currentProps.includeTypes) || !arrayEqual(newProps.excludeTypes, currentProps.excludeTypes) || newProps.aromaticBonds !== currentProps.aromaticBonds || newProps.multipleBonds !== currentProps.multipleBonds); const newUnit = newStructureGroup.group.units[0]; const currentUnit = currentStructureGroup.group.units[0]; if (Unit.isAtomic(newUnit) && Unit.isAtomic(currentUnit)) { if (!IntAdjacencyGraph.areEqual(newUnit.bonds, currentUnit.bonds)) { state.createGeometry = true; state.updateTransform = true; state.updateColor = true; state.updateSize = true; } } } }, materialId); } // function getStructureIntraUnitBondLineBuilderProps(structure, theme, props) { const intraUnitProps = []; const { bondCount, unitIndex, unitEdgeIndex, unitGroupIndex } = structure.intraUnitBondMapping; const { child } = structure; for (const ug of structure.unitSymmetryGroups) { const unit = ug.units[0]; const childUnit = child === null || child === void 0 ? void 0 : child.unitMap.get(unit.id); const p = Unit.isAtomic(unit) && !(child && !childUnit) ? getIntraUnitBondLineBuilderProps(unit, structure, theme, props) : EmptyLinkBuilderProps; intraUnitProps.push({ group: ug, props: p }); } return { linkCount: bondCount, referencePosition: (edgeIndex) => { const { group, props } = intraUnitProps[unitIndex[edgeIndex]]; if (!props.referencePosition) return null; const v = props.referencePosition(unitEdgeIndex[edgeIndex]); if (!v) return null; const u = group.units[unitGroupIndex[edgeIndex]]; Vec3.transformMat4(v, v, u.conformation.operator.matrix); return v; }, position: (posA, posB, edgeIndex, adjust) => { const { group, props } = intraUnitProps[unitIndex[edgeIndex]]; props.position(posA, posB, unitEdgeIndex[edgeIndex], adjust); const u = group.units[unitGroupIndex[edgeIndex]]; Vec3.transformMat4(posA, posA, u.conformation.operator.matrix); Vec3.transformMat4(posB, posB, u.conformation.operator.matrix); }, style: (edgeIndex) => { const { props } = intraUnitProps[unitIndex[edgeIndex]]; return props.style ? props.style(unitEdgeIndex[edgeIndex]) : 0 /* LinkStyle.Solid */; }, radius: (edgeIndex) => { const { props } = intraUnitProps[unitIndex[edgeIndex]]; return props.radius(unitEdgeIndex[edgeIndex]); }, ignore: (edgeIndex) => { const { props } = intraUnitProps[unitIndex[edgeIndex]]; return props.ignore ? props.ignore(unitEdgeIndex[edgeIndex]) : false; }, stub: (edgeIndex) => { const { props } = intraUnitProps[unitIndex[edgeIndex]]; return props.stub ? props.stub(unitEdgeIndex[edgeIndex]) : false; } }; } function createStructureIntraUnitBondLines(ctx, structure, theme, props, lines) { if (!hasStructureVisibleBonds(structure, props)) return Lines.createEmpty(lines); if (!structure.intraUnitBondMapping.bondCount) return Lines.createEmpty(lines); const builderProps = getStructureIntraUnitBondLineBuilderProps(structure, theme, props); const { lines: l, boundingSphere } = createLinkLines(ctx, builderProps, props, lines); if (boundingSphere) { l.setBoundingSphere(boundingSphere); } else if (l.lineCount > 0) { const { child } = structure; const sphere = Sphere3D.expand(Sphere3D(), (child !== null && child !== void 0 ? child : structure).boundary.sphere, 1 * props.sizeFactor); l.setBoundingSphere(sphere); } return l; } export const StructureIntraUnitBondLineParams = { ...ComplexLinesParams, ...BondLineParams, includeParent: PD.Boolean(false), }; export function StructureIntraUnitBondLineVisual(materialId) { return ComplexLinesVisual({ defaultProps: PD.getDefaultValues(StructureIntraUnitBondLineParams), createGeometry: createStructureIntraUnitBondLines, createLocationIterator: (structure, props) => { return !hasStructureVisibleBonds(structure, props) ? EmptyLocationIterator : BondIterator.fromStructureGroups(structure); }, getLoci: getStructureGroupsBondLoci, eachLocation: eachStructureGroupsBond, setUpdateState: (state, newProps, currentProps, newTheme, currentTheme, newStructure, currentStructure) => { state.createGeometry = (newProps.sizeFactor !== currentProps.sizeFactor || newProps.linkScale !== currentProps.linkScale || newProps.linkSpacing !== currentProps.linkSpacing || newProps.aromaticDashCount !== currentProps.aromaticDashCount || newProps.dashCount !== currentProps.dashCount || newProps.ignoreHydrogens !== currentProps.ignoreHydrogens || newProps.ignoreHydrogensVariant !== currentProps.ignoreHydrogensVariant || !arrayEqual(newProps.includeTypes, currentProps.includeTypes) || !arrayEqual(newProps.excludeTypes, currentProps.excludeTypes) || newProps.multipleBonds !== currentProps.multipleBonds); if (hasStructureVisibleBonds(newStructure, newProps) && newStructure.interUnitBonds !== currentStructure.interUnitBonds) { state.createGeometry = true; state.updateTransform = true; state.updateColor = true; state.updateSize = true; } } }, materialId); }