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molstar

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A comprehensive macromolecular library.

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/** * Copyright (c) 2018-2022 mol* contributors, licensed under MIT, See LICENSE file for more info. * * @author Alexander Rose <alexander.rose@weirdbyte.de> */ import { Box3D, fillGridDim } from '../../geometry'; import { Vec3, Mat4, Tensor } from '../../linear-algebra'; import { OrderedSet } from '../../../mol-data/int'; import { fasterExp } from '../../approx'; export async function GaussianDensityCPU(ctx, position, box, radius, props) { const { resolution, radiusOffset, smoothness } = props; const scaleFactor = 1 / resolution; const { indices, x, y, z, id } = position; const n = OrderedSet.size(indices); const radii = new Float32Array(n); let maxRadius = 0; for (let i = 0; i < n; ++i) { const r = radius(OrderedSet.getAt(indices, i)) + radiusOffset; if (maxRadius < r) maxRadius = r; radii[i] = r; } const pad = maxRadius * 2 + resolution; const expandedBox = Box3D.expand(Box3D(), box, Vec3.create(pad, pad, pad)); const min = expandedBox.min; const scaledBox = Box3D.scale(Box3D(), expandedBox, scaleFactor); const dim = Box3D.size(Vec3(), scaledBox); Vec3.ceil(dim, dim); const space = Tensor.Space(dim, [0, 1, 2], Float32Array); const data = space.create(); const field = Tensor.create(space, data); const idData = space.create(); idData.fill(-1); const idField = Tensor.create(space, idData); const [dimX, dimY, dimZ] = dim; const iu = dimZ, iv = dimY, iuv = iu * iv; const gridx = fillGridDim(dim[0], min[0], resolution); const gridy = fillGridDim(dim[1], min[1], resolution); const gridz = fillGridDim(dim[2], min[2], resolution); const densData = space.create(); const alpha = smoothness; const updateChunk = Math.ceil(100000 / ((Math.pow(Math.pow(maxRadius, 3), 3) * scaleFactor))); function accumulateRange(begI, endI) { for (let i = begI; i < endI; ++i) { const j = OrderedSet.getAt(indices, i); const vx = x[j], vy = y[j], vz = z[j]; const rad = radii[i]; const rSq = rad * rad; const rSqInv = 1 / rSq; const r2 = rad * 2; const r2sq = r2 * r2; // Number of grid points, round this up... const ng = Math.ceil(r2 * scaleFactor); // Center of the atom, mapped to grid points (take floor) const iax = Math.floor(scaleFactor * (vx - min[0])); const iay = Math.floor(scaleFactor * (vy - min[1])); const iaz = Math.floor(scaleFactor * (vz - min[2])); // Extents of grid to consider for this atom const begX = Math.max(0, iax - ng); const begY = Math.max(0, iay - ng); const begZ = Math.max(0, iaz - ng); // Add two to these points: // - iax are floor'd values so this ensures coverage // - these are loop limits (exclusive) const endX = Math.min(dimX, iax + ng + 2); const endY = Math.min(dimY, iay + ng + 2); const endZ = Math.min(dimZ, iaz + ng + 2); for (let xi = begX; xi < endX; ++xi) { const dx = gridx[xi] - vx; const xIdx = xi * iuv; for (let yi = begY; yi < endY; ++yi) { const dy = gridy[yi] - vy; const dxySq = dx * dx + dy * dy; const xyIdx = yi * iu + xIdx; for (let zi = begZ; zi < endZ; ++zi) { const dz = gridz[zi] - vz; const dSq = dxySq + dz * dz; if (dSq <= r2sq) { const dens = fasterExp(-alpha * (dSq * rSqInv)); const idx = zi + xyIdx; data[idx] += dens; if (dens > densData[idx]) { densData[idx] = dens; idData[idx] = id ? id[i] : i; } } } } } } } async function accumulate() { for (let i = 0; i < n; i += updateChunk) { accumulateRange(i, Math.min(i + updateChunk, n)); if (ctx.shouldUpdate) { await ctx.update({ message: 'filling density grid', current: i, max: n }); } } } // console.time('gaussian density cpu') await accumulate(); // console.timeEnd('gaussian density cpu') const transform = Mat4.identity(); Mat4.fromScaling(transform, Vec3.create(resolution, resolution, resolution)); Mat4.setTranslation(transform, expandedBox.min); return { field, idField, transform, radiusFactor: 1, resolution, maxRadius }; }