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/*! *****************************************************************************
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License at http://www.apache.org/licenses/LICENSE-2.0

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Actions are untracked and will not trigger on state changes. Use `reaction` or wrap only your state modification code in an action.",m006:"Warning: attempted to pass an action to autorunAsync. Actions are untracked and will not trigger on state changes. Use `reaction` or wrap only your state modification code in an action.",m007:"reaction only accepts 2 or 3 arguments. If migrating from MobX 2, please provide an options object",m008:"wrapping reaction expression in `asReference` is no longer supported, use options object instead",m009:"@computed can only be used on getter functions, like: '@computed get myProps() { return ...; }'. It looks like it was used on a property.",m010:"@computed can only be used on getter functions, like: '@computed get myProps() { return ...; }'",m011:"First argument to `computed` should be an expression. If using computed as decorator, don't pass it arguments",m012:"computed takes one or two arguments if used as function",m013:"[mobx.expr] 'expr' should only be used inside other reactive functions.",m014:"extendObservable expected 2 or more arguments",m015:"extendObservable expects an object as first argument",m016:"extendObservable should not be used on maps, use map.merge instead",m017:"all arguments of extendObservable should be objects",m018:"extending an object with another observable (object) is not supported. Please construct an explicit propertymap, using `toJS` if need. See issue #540",m019:"[mobx.isObservable] isObservable(object, propertyName) is not supported for arrays and maps. Use map.has or array.length instead.",m020:"modifiers can only be used for individual object properties",m021:"observable expects zero or one arguments",m022:"@observable can not be used on getters, use @computed instead",m024:"whyRun() can only be used if a derivation is active, or by passing an computed value / reaction explicitly. If you invoked whyRun from inside a computation; the computation is currently suspended but re-evaluating because somebody requested its value.",m025:"whyRun can only be used on reactions and computed values",m026:"`action` can only be invoked on functions",m028:"It is not allowed to set `useStrict` when a derivation is running",m029:"INTERNAL ERROR only onBecomeUnobserved shouldn't be called twice in a row",m030a:"Since strict-mode is enabled, changing observed observable values outside actions is not allowed. Please wrap the code in an `action` if this change is intended. Tried to modify: ",m030b:"Side effects like changing state are not allowed at this point. Are you trying to modify state from, for example, the render function of a React component? Tried to modify: ",m031:"Computed values are not allowed to cause side effects by changing observables that are already being observed. Tried to modify: ",m032:"* This computation is suspended (not in use by any reaction) and won't run automatically.\n\tDidn't expect this computation to be suspended at this point?\n\t  1. Make sure this computation is used by a reaction (reaction, autorun, observer).\n\t  2. Check whether you are using this computation synchronously (in the same stack as they reaction that needs it).",m033:"`observe` doesn't support the fire immediately property for observable maps.",m034:"`mobx.map` is deprecated, use `new ObservableMap` or `mobx.observable.map` instead",m035:"Cannot make the designated object observable; it is not extensible",m036:"It is not possible to get index atoms from arrays",m037:'Hi there! I\'m sorry you have just run into an exception.\nIf your debugger ends up here, know that some reaction (like the render() of an observer component, autorun or reaction)\nthrew an exception and that mobx caught it, to avoid that it brings the rest of your application down.\nThe original cause of the exception (the code that caused this reaction to run (again)), is still in the stack.\n\nHowever, more interesting is the actual stack trace of the error itself.\nHopefully the error is an instanceof Error, because in that case you can inspect the original stack of the error from where it was thrown.\nSee `error.stack` property, or press the very subtle "(...)" link you see near the console.error message that probably brought you here.\nThat stack is more interesting than the stack of this console.error itself.\n\nIf the exception you see is an exception you created yourself, make sure to use `throw new Error("Oops")` instead of `throw "Oops"`,\nbecause the javascript environment will only preserve the original stack trace in the first form.\n\nYou can also make sure the debugger pauses the next time this very same exception is thrown by enabling "Pause on caught exception".\n(Note that it might pause on many other, unrelated exception as well).\n\nIf that all doesn\'t help you out, feel free to open an issue https://github.com/mobxjs/mobx/issues!\n',m038:"Missing items in this list?\n    1. 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antibiotic is required.");if(!r)throw new Error("Resistance: Argument bacterium is required.");t.forEach(function(e){s.values.push(new l.default(e.type,e.value,e.sampleSize,e.confidenceInterval))}),this.antibiotic=n,this.bacterium=r}return(0,s.default)(e,[{key:"getValuesByPrecision",value:function(){return this.values.sort(function(e,t){return e.type.precision>t.type.precision?-1:1})}}]),e}(),i=function(e,t,n,r,i){var o={};return Object.keys(r).forEach(function(e){o[e]=r[e]}),o.enumerable=!!o.enumerable,o.configurable=!!o.configurable,("value"in o||o.initializer)&&(o.writable=!0),o=n.slice().reverse().reduce(function(n,r){return r(e,t,n)||n},o),i&&void 0!==o.initializer&&(o.value=o.initializer?o.initializer.call(i):void 0,o.initializer=void 0),void 0===o.initializer&&(Object.defineProperty(e,t,o),o=null),o}(r.prototype,"values",[u.observable],{enumerable:!0,initializer:function(){return[]}}),r);t.default=f},function(e,t,n){"use 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0!==arguments[1]?arguments[1]:[],r=arguments[2];(0,b.observe)(e.status,function(n){"ready"===n.newValue&&e.getAsArray().forEach(function(e){t.addAntibiotic(e)})}),(0,b.observe)(n.status,function(e){"ready"===e.newValue&&n.getAsArray().forEach(function(e){t.addBacterium(e)})}),(0,b.observe)(n.get(),function(e){"delete"===e.type&&t.removeBacterium(e.oldValue)}),(0,b.observe)(r.status,function(e){"ready"===e.newValue&&(t._clearResistances(),r.getAsArray().forEach(function(e){t.addResistance(e)}))})}},{key:"_clearResistances",value:function(){this._resistances.clear()}},{key:"setOffsetFilters",value:function(e){this._offsetFilters=e}},{key:"getOffsetFilters",value:function(){return this._offsetFilters}},{key:"setSelectedFilters",value:function(e){this._selectedFilters=e}},{key:"addAntibiotic",value:function(e){var t=this;if(this._antibiotics.has(e.id))throw new Error("MatrixView: Trying to add antibiotic with duplicate key "+e.id+".");this._antibiotics.set(e.id,new w.default(e,this)),F("Added antibiotic %o, number is %d",e,this._antibiotics.size),e.getSubstanceClasses().forEach(function(e){t._substanceClasses.has(e.id)||t._substanceClasses.set(e.id,new E.default(e,t))})}},{key:"getAntibioticView",value:function(e){return this._antibiotics.get(e.id)}},{key:"setAntibioticLabelDimensions",value:function(e,t,n){if(t%1!=0||n%1!=0)throw new Error("MatrixView: Width and height for antibiotic labels must be integers.");var r=this._antibioticLabelDimensions.get(e);r&&r.height===n&&r.width===t||(this._antibioticLabelDimensions.set(e,{width:t,height:n}),this._calculateAntibioticLabelRowHeight(),this._calculateDefaultRadius())}},{key:"_calculateAntibioticLabelRowHeight",value:function(){this._antibioticLabelDimensions.size===this.sortedAntibiotics.length&&(this.antibioticLabelRowHeight=(0,p.default)(this._antibioticLabelDimensions.values()).reduce(function(e,t){return Math.max(e,t.height)},0),F("antibioticLabelRowHeight is 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t=e.getValuesByPrecision()[0];(0===this.sampleSizeExtremes.min||t.sampleSize<this.sampleSizeExtremes.min)&&(this.sampleSizeExtremes.min=t.sampleSize),t.sampleSize>this.sampleSizeExtremes.max&&(this.sampleSizeExtremes.max=t.sampleSize)}},{key:"setActiveResistance",value:function(e){this.activeResistance=e}},{key:"setDimensions",value:function(e){F("Set dimensions to %o",e),e&&(this._dimensions&&this._dimensions.height===e.height&&this._dimensions.width===e.width||(this._dimensions={height:e.height,width:e.width},this._calculateDefaultRadius()))}},{key:"_calculateDefaultRadius",value:function(){if(this._bacteria.size&&this._bacteriaLabelWidths.size===this._bacteria.size&&this._dimensions&&void 0!==this.antibioticLabelRowHeight){F("Calculate default radius");var e=this._antibiotics.size,t=this.sortedAntibiotics.reduce(function(e,t){if(!e.item)return{count:0,item:t};var n=(0,C.default)(e.item.antibiotic.getSubstanceClasses(),t.antibiotic.getSubstanceClasses());return{count:n.removed.length||n.added.length?e.count+1:e.count,item:t}},{count:0,item:void 0}).count;F("Calculate defaultRadius; bacteriumLabelColumnWidth is %d, numberOfAntibiotics %d, numberOfSubstanceClassChanges %d, width %d",this.bacteriumLabelColumnWidth,e,t,this._dimensions.width);var n=this._dimensions.width-this.space-this.bacteriumLabelColumnWidth-this.antibioticLabelRowHeight,r=(e+t)*this.space;this.defaultRadius=Math.max(Math.floor((n-r)/e/2),1),F("Available space: %d. 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They work not for but with our customers to build web applications that solve complex problems with simple user interfaces. Like this one."),l.default.createElement("h1",{id:"contact"},"Contact"),l.default.createElement("p",null,"Questions or feedback regarding the INFECT Project"),l.default.createElement("div",{className:"adresses"},l.default.createElement("address",null,"Pascal Frey, MD, MSc",l.default.createElement("br",null),"INFECT Project Leader",l.default.createElement("br",null),l.default.createElement("a",{href:"mailto:info@infect.info"},"info@infect.info"),l.default.createElement("br",null),"Department of General Internal Medicine",l.default.createElement("br",null),"Berne University Hospital, 3010 Bern",l.default.createElement("br",null))),l.default.createElement("p",null,"INFECT is developed and maintained by Joinbox"),l.default.createElement("div",{className:"adresses"},l.default.createElement("address",null,"Joinbox GmbH",l.default.createElement("br",null),l.default.createElement("a",{href:"mailto:hello@joinbox.com"},"hello@joinbox.com"),l.default.createElement("br",null),"3012 Bern",l.default.createElement("br",null))),l.default.createElement("h1",{id:"partners"},"Partners"),l.default.createElement("p",null,l.default.createElement("a",{href:"http://www.anresis.ch",target:"_blank"},"Swiss Centre for Antibiotic resistance (anresis)"),l.default.createElement("br",null),l.default.createElement("a",{href:"http://ifik.unibe.ch",target:"_blank"},"Institute for Infectious Diseases, University of Bern"),l.default.createElement("br",null),l.default.createElement("a",{href:"https://www.bag.admin.ch/bag/en/home.html",target:"_blank"},"Swiss Federal Office of Public Health")),l.default.createElement("h1",{id:"disclaimer"},"Disclaimer"),l.default.createElement("p",null,"INFECT maintains this website to enhance public access to information about antibiotic resistance, antibiotic consumption and its control. Our goal is to keep this information timely and accurate and to minimize disruption caused by technical errors. However, some data or information on our site may have been created or structured in files or formats that are not error-free and we cannot guarantee that our service will not be interrupted or otherwise affected by such problems. If errors are brought to our attention, we will try to correct them as soon as possible."),l.default.createElement("p",null,"INFECT accepts no responsibility or liability with regard to such problems incurred as a result of using this site or any linked external sites."),l.default.createElement("p",null,"This information is:"),l.default.createElement("ul",null,l.default.createElement("li",null,"of a general nature only and is not intended to address the specific circumstances of any particular individual or entity;"),l.default.createElement("li",null,"not necessarily comprehensive, complete, accurate or up to date;"),l.default.createElement("li",null,"sometimes linked to external sources over which INFECT has no control and for which INFECT assumes neither responsibility nor liability;"),l.default.createElement("li",null,"not professional or medical advice (if you need specific advice, you should always consult a suitably qualified professional).")),l.default.createElement("p",null,"Although INFECT is intended to be used to guide and support an optimal empirical antimicrobial therapy, its use does not substitute a thorough investigation of patients’ signs and symptoms, or sound diagnostic and therapeutic reasoning. Although all data is routinely checked for correctness, there is always a possibility of error. 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