ibowankenobi-i-pv
Version:
Interactive Protein Sequence VIsualization/Viewer - Interactive Circos
10,621 lines • 1.5 MB
HTML
<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8" name="viewport" content="width=device-width, initial-scale=1">
<meta http-equiv="Content-Security-Policy" content="script-src 'self' 'unsafe-inline' 'unsafe-eval' https://d3js.org https://nytimes.github.io;">
<title>NewDataset</title>
<script src="https://d3js.org/d3.v3.min.js" integrity="sha384-N8EP0Yml0jN7e0DcXlZ6rt+iqKU9Ck6f1ZQ+j2puxatnBq4k9E8Q6vqBcY34LNbn" crossorigin="anonymous" charset="utf-8"></script>
<!-- download.js v4.21 inlined to avoid loading from untrusted external domain -->
<script integrity="sha384-nY//GSjxOK1d2nES1eVh+14TsPkwGkMou79BvNz975x7s0pKK7zp9rjK5J+yvN0F">
//download.js v4.21, by dandavis; 2008-2018. [MIT] see https://github.com/rndme/download for tests/usage
(function (root, factory) {
if (typeof define === 'function' && define.amd) {
define([], factory);
} else if (typeof exports === 'object') {
module.exports = factory();
} else {
root.download = factory();
}
}(this, function () {
return function download(data, strFileName, strMimeType) {
var self = window,
defaultMime = "application/octet-stream",
mimeType = strMimeType || defaultMime,
payload = data,
url = !strFileName && !strMimeType && payload,
anchor = document.createElement("a"),
toString = function(a){return String(a);},
myBlob = (self.Blob || self.MozBlob || self.WebKitBlob || toString),
fileName = strFileName || "download",
blob,
reader;
myBlob= myBlob.call ? myBlob.bind(self) : Blob ;
if(String(this)==="true"){
payload=[payload, mimeType];
mimeType=payload[0];
payload=payload[1];
}
if(url && url.length< 2048){
fileName = url.split("/").pop().split("?")[0];
anchor.href = url;
if(anchor.href.indexOf(url) !== -1){
var ajax=new XMLHttpRequest();
ajax.open( "GET", url, true);
ajax.responseType = 'blob';
ajax.onload= function(e){
download(e.target.response, fileName, defaultMime);
};
setTimeout(function(){ ajax.send();}, 0);
return ajax;
}
}
if(/^data:([\w+-]+\/[\w+.-]+)?[,;]/.test(payload)){
if(payload.length > (1024*1024*1.999) && myBlob !== toString ){
payload=dataUrlToBlob(payload);
mimeType=payload.type || defaultMime;
}else{
return navigator.msSaveBlob ?
navigator.msSaveBlob(dataUrlToBlob(payload), fileName) :
saver(payload) ;
}
}else{
if(/([\x80-\xff])/.test(payload)){
var i=0, tempUiArr= new Uint8Array(payload.length), mx=tempUiArr.length;
for(i;i<mx;++i) tempUiArr[i]= payload.charCodeAt(i);
payload=new myBlob([tempUiArr], {type: mimeType});
}
}
blob = payload instanceof myBlob ?
payload :
new myBlob([payload], {type: mimeType}) ;
function dataUrlToBlob(strUrl) {
var parts= strUrl.split(/[:;,]/),
type= parts[1],
indexDecoder = strUrl.indexOf("charset")>0 ? 3: 2,
decoder= parts[indexDecoder] == "base64" ? atob : decodeURIComponent,
binData= decoder( parts.pop() ),
mx= binData.length,
i= 0,
uiArr= new Uint8Array(mx);
for(i;i<mx;++i) uiArr[i]= binData.charCodeAt(i);
return new myBlob([uiArr], {type: type});
}
function saver(url, winMode){
if ('download' in anchor) {
anchor.href = url;
anchor.setAttribute("download", fileName);
anchor.className = "download-js-link";
anchor.innerHTML = "downloading...";
anchor.style.display = "none";
anchor.addEventListener('click', function(e) {
e.stopPropagation();
this.removeEventListener('click', arguments.callee);
});
document.body.appendChild(anchor);
setTimeout(function() {
anchor.click();
document.body.removeChild(anchor);
if(winMode===true){setTimeout(function(){ self.URL.revokeObjectURL(anchor.href);}, 250 );}
}, 66);
return true;
}
if(/(Version)\/(\d+)\.(\d+)(?:\.(\d+))?.*Safari\//.test(navigator.userAgent)) {
if(/^data:/.test(url)) url="data:"+url.replace(/^data:([\w\/\-\+]+)/, defaultMime);
if(!window.open(url)){
if(confirm("Displaying New Document\n\nUse Save As... to download, then click back to return to this page.")){ location.href=url; }
}
return true;
}
var f = document.createElement("iframe");
document.body.appendChild(f);
if(!winMode && /^data:/.test(url)){
url="data:"+url.replace(/^data:([\w\/\-\+]+)/, defaultMime);
}
f.src=url;
setTimeout(function(){ document.body.removeChild(f); }, 333);
}
if (navigator.msSaveBlob) {
return navigator.msSaveBlob(blob, fileName);
}
if(self.URL){
saver(self.URL.createObjectURL(blob), true);
}else{
if(typeof blob === "string" || blob.constructor===toString ){
try{
return saver( "data:" + mimeType + ";base64," + self.btoa(blob) );
}catch(y){
return saver( "data:" + mimeType + "," + encodeURIComponent(blob) );
}
}
reader=new FileReader();
reader.onload=function(e){
saver(this.result);
};
reader.readAsDataURL(blob);
}
return true;
};
}));
</script>
<style type ="text/css">
html {
transition: background-color 1s ease;
}
div.bar {
display: inline-block;
width: 20px;
height: 75px;
background-color: teal;
margin-right: 2px;
}
.axis path,
.axis line {
fill: none;
stroke: black;
shape-rendering: crispEdges;
}
.axis text {
stroke: black;
font-family: sans-serif;
font-size: 11px;
}
body {
position:relative;
transition: background-color 1s ease;
width: 1500px;
height: 1500px;
margin-left: auto;
margin-right: auto;
}
#master {
position: absolute;
top: 0%;
left: 0%;
height:1500px;
width: 1500px;
}
#ipvWatchIcon {
transition: opacity 1s ease, visibility 1s ease;
}
#colorCoding {
transition: fill 1s ease, opacity 1s ease, visibility 1s ease;
}
#neonEffect {
transition: fill 1s ease, opacity 1s ease, visibility 1s ease;
}
#logo {
transition: opacity 1s ease;
}
.htmlElements,.htmlElementsInputs {
transition: opacity 1s ease, background 1s ease, visibility 1s ease, box-shadow 1s ease, border-width 0.2s ease, border-color 1s ease;
}
.DropDownRectMark {
transition: opacity 1s ease, visibility 1s ease;
}
.DropDownRectExtract {
transition: opacity 1s ease, visibility 1s ease;
}
.markElements {
//opacity: 0;
//transition: opacity 1.5s ease;
}
.overviews {
transition: fill 1s ease, stroke 1s ease, opacity 1s ease, visibility 1s ease;
}
#OverviewMark,#OverviewLength {
transition: opacity 1s ease;
}
.highlightIcons {
transition: opacity 1s ease;
}
.higlightRoundnessControls {
transition: fill 1s ease, opacity 1s ease, visibility 1s ease;
}
#fileUploadIcon {
transition: opacity 1s ease, visibility 0.1s ease;
}
.actionOptions {
transition: fill 1s ease, opacity 1s ease, visibility 0.1s ease;
}
.histogramIcons {
transition: opacity 0.5s ease;
}
.indorilLogo {
transition: opacity 1s ease, visibility 1s ease;
}
</style>
</head>
<body>
<svg id="master" preserveAspectRatio="xMidYMid" viewBox ="-500 0 7000 6000" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g id="ideograms">
<path d="M3098.013,755.139 A2247.000,2247.000 40.000 1,1 2923.758,754.294 L2923.656,751.296 A2250.000,2250.000 0.000 1,0 3098.144,752.142 Z" style="stroke-width:4.0;stroke:rgb(37,37,37);stroke-linecap:round;fill:rgb(82,82,82);" />
<text x="2985.4" y="6004.0" font-size="104.0px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(115,115,115);" transform="rotate(0.3,2985.4,6004.0)" >ACE2</text>
<path d="M3098.013,755.139 A2247.000,2247.000 40.000 1,1 2923.758,754.294 L2923.656,751.296 A2250.000,2250.000 0.000 1,0 3098.144,752.142 Z" style="stroke-width:4.0;stroke:rgb(37,37,37);stroke-linecap:round;fill:none;" />
</g>
<g id="plot0">
<g id="plot0-axis">
</g>
<path d="M3098.144,752.142 A2250.000,2250.000 40.000 0,1 3115.469,752.965 L3123.552,595.672 A2407.500,2407.500 0.000 0,0 3105.014,594.791 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_1_Conservation-Score_7"/>
<path d="M3115.469,752.965 A2250.000,2250.000 40.000 0,1 3132.787,753.922 L3138.099,664.079 A2340.000,2340.000 0.000 0,0 3120.088,663.083 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_2_Conservation-Score_4"/>
<path d="M3132.787,753.922 A2250.000,2250.000 40.000 0,1 3150.098,755.012 L3154.601,687.662 A2317.500,2317.500 0.000 0,0 3136.771,686.539 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_3_Conservation-Score_3"/>
<path d="M3150.098,755.012 A2250.000,2250.000 40.000 0,1 3167.400,756.236 L3179.117,599.172 A2407.500,2407.500 0.000 0,0 3160.605,597.863 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_4_Conservation-Score_7"/>
<path d="M3167.400,756.236 A2250.000,2250.000 40.000 0,1 3184.691,757.593 L3193.926,645.473 A2362.500,2362.500 0.000 0,0 3175.769,644.048 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_5_Conservation-Score_5"/>
<path d="M3184.691,757.593 A2250.000,2250.000 40.000 0,1 3201.972,759.083 L3220.149,557.401 A2452.500,2452.500 0.000 0,0 3201.313,555.776 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_6_Conservation-Score_10"/>
<path d="M3201.972,759.083 A2250.000,2250.000 40.000 0,1 3219.241,760.707 L3236.780,581.563 A2430.000,2430.000 0.000 0,0 3218.130,579.810 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_7_Conservation-Score_8"/>
<path d="M3219.241,760.707 A2250.000,2250.000 40.000 0,1 3236.496,762.464 L3248.321,650.587 A2362.500,2362.500 0.000 0,0 3230.203,648.742 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_8_Conservation-Score_5"/>
<path d="M3236.496,762.464 A2250.000,2250.000 40.000 0,1 3253.738,764.353 L3268.962,630.214 A2385.000,2385.000 0.000 0,0 3250.686,628.211 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_9_Conservation-Score_6"/>
<path d="M3253.738,764.353 A2250.000,2250.000 40.000 0,1 3270.964,766.376 L3284.513,654.694 A2362.500,2362.500 0.000 0,0 3266.425,652.571 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_10_Conservation-Score_5"/>
<path d="M3270.964,766.376 A2250.000,2250.000 40.000 0,1 3288.175,768.531 L3305.465,634.643 A2385.000,2385.000 0.000 0,0 3287.222,632.358 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_11_Conservation-Score_6"/>
<path d="M3288.175,768.531 A2250.000,2250.000 40.000 0,1 3305.368,770.818 L3320.637,659.359 A2362.500,2362.500 0.000 0,0 3302.584,656.957 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_12_Conservation-Score_5"/>
<path d="M3305.368,770.818 A2250.000,2250.000 40.000 0,1 3322.543,773.239 L3345.121,617.365 A2407.500,2407.500 0.000 0,0 3326.744,614.776 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_13_Conservation-Score_7"/>
<path d="M3322.543,773.239 A2250.000,2250.000 40.000 0,1 3339.699,775.791 L3346.493,731.307 A2295.000,2295.000 0.000 0,0 3328.994,728.703 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_14_Conservation-Score_1"/>
<path d="M3339.699,775.791 A2250.000,2250.000 40.000 0,1 3356.835,778.476 L3363.972,734.046 A2295.000,2295.000 0.000 0,0 3346.493,731.307 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_15_Conservation-Score_1"/>
<path d="M3356.835,778.476 A2250.000,2250.000 40.000 0,1 3373.950,781.293 L3377.689,759.106 A2272.500,2272.500 0.000 0,0 3360.403,756.261 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_16_Conservation-Score_0"/>
<path d="M3373.950,781.293 A2250.000,2250.000 40.000 0,1 3391.042,784.241 L3402.773,717.769 A2317.500,2317.500 0.000 0,0 3385.168,714.732 Z" style="stroke-width:3.0;stroke:rgb(115,115,115);stroke-linecap:round;fill:rgb(82,82,82);" id="Residue_17_Conservation-Score_2"/>
<path d="M3391.042,784.241 A2250.000,2250.000 40.000 0,1 3408.111,787.322 L3416.273,743.068 A2295.000,2295.000 0.000 0,0 3398.863,739.926 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_18_Conservation-Score_1" class="Extracellular"/>
<path d="M3408.111,787.322 A2250.000,2250.000 40.000 0,1 3425.156,790.533 L3437.911,724.249 A2317.500,2317.500 0.000 0,0 3420.354,720.941 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_19_Conservation-Score_3" class="Extracellular"/>
<path d="M3425.156,790.533 A2250.000,2250.000 40.000 0,1 3442.176,793.877 L3451.019,749.754 A2295.000,2295.000 0.000 0,0 3433.659,746.344 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_20_Conservation-Score_1" class="Extracellular"/>
<path d="M3442.176,793.877 A2250.000,2250.000 40.000 0,1 3459.169,797.351 L3477.536,709.245 A2340.000,2340.000 0.000 0,0 3459.863,705.632 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_21_Conservation-Score_4"/>
<path d="M3459.169,797.351 A2250.000,2250.000 40.000 0,1 3476.135,800.956 L3504.703,669.013 A2385.000,2385.000 0.000 0,0 3486.719,665.192 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_22_Conservation-Score_6" class="Extracellular"/>
<path d="M3476.135,800.956 A2250.000,2250.000 40.000 0,1 3493.073,804.692 L3522.657,672.973 A2385.000,2385.000 0.000 0,0 3504.703,669.013 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_23_Conservation-Score_6"/>
<path d="M3493.073,804.692 A2250.000,2250.000 40.000 0,1 3509.981,808.558 L3530.381,720.900 A2340.000,2340.000 0.000 0,0 3512.796,716.879 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_24_Conservation-Score_4"/>
<path d="M3509.981,808.558 A2250.000,2250.000 40.000 0,1 3526.859,812.554 L3547.934,725.056 A2340.000,2340.000 0.000 0,0 3530.381,720.900 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_25_Conservation-Score_4" class="Extracellular"/>
<path d="M3526.859,812.554 A2250.000,2250.000 40.000 0,1 3543.706,816.681 L3565.455,729.348 A2340.000,2340.000 0.000 0,0 3547.934,725.056 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_26_Conservation-Score_4"/>
<path d="M3543.706,816.681 A2250.000,2250.000 40.000 0,1 3560.521,820.937 L3577.336,755.565 A2317.500,2317.500 0.000 0,0 3560.017,751.181 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_27_Conservation-Score_3" class="Extracellular"/>
<path d="M3560.521,820.937 A2250.000,2250.000 40.000 0,1 3577.302,825.322 L3617.713,673.095 A2407.500,2407.500 0.000 0,0 3599.757,668.402 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_28_Conservation-Score_7"/>
<path d="M3577.302,825.322 A2250.000,2250.000 40.000 0,1 3594.049,829.837 L3605.930,786.434 A2295.000,2295.000 0.000 0,0 3588.848,781.829 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_29_Conservation-Score_1"/>
<path d="M3594.049,829.837 A2250.000,2250.000 40.000 0,1 3610.761,834.481 L3622.976,791.171 A2295.000,2295.000 0.000 0,0 3605.930,786.434 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_30_Conservation-Score_1"/>
<path d="M3610.761,834.481 A2250.000,2250.000 40.000 0,1 3627.436,839.254 L3639.985,796.039 A2295.000,2295.000 0.000 0,0 3622.976,791.171 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_31_Conservation-Score_1"/>
<path d="M3627.436,839.254 A2250.000,2250.000 40.000 0,1 3644.074,844.155 L3663.396,779.479 A2317.500,2317.500 0.000 0,0 3646.259,774.431 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_32_Conservation-Score_2"/>
<path d="M3644.074,844.155 A2250.000,2250.000 40.000 0,1 3660.674,849.184 L3680.494,784.659 A2317.500,2317.500 0.000 0,0 3663.396,779.479 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_33_Conservation-Score_2" class="Extracellular"/>
<path d="M3660.674,849.184 A2250.000,2250.000 40.000 0,1 3677.234,854.341 L3684.007,832.884 A2272.500,2272.500 0.000 0,0 3667.280,827.676 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_34_Conservation-Score_0"/>
<path d="M3677.234,854.341 A2250.000,2250.000 40.000 0,1 3693.754,859.625 L3714.567,795.414 A2317.500,2317.500 0.000 0,0 3697.551,789.971 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_35_Conservation-Score_3"/>
<path d="M3693.754,859.625 A2250.000,2250.000 40.000 0,1 3710.233,865.037 L3738.643,779.638 A2340.000,2340.000 0.000 0,0 3721.505,774.010 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_36_Conservation-Score_4" class="Extracellular"/>
<path d="M3710.233,865.037 A2250.000,2250.000 40.000 0,1 3726.670,870.575 L3755.737,785.398 A2340.000,2340.000 0.000 0,0 3738.643,779.638 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_37_Conservation-Score_4"/>
<path d="M3726.670,870.575 A2250.000,2250.000 40.000 0,1 3743.064,876.240 L3772.786,791.290 A2340.000,2340.000 0.000 0,0 3755.737,785.398 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_38_Conservation-Score_4"/>
<path d="M3743.064,876.240 A2250.000,2250.000 40.000 0,1 3759.413,882.031 L3782.196,818.492 A2317.500,2317.500 0.000 0,0 3765.356,812.527 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_39_Conservation-Score_3" class="Extracellular"/>
<path d="M3759.413,882.031 A2250.000,2250.000 40.000 0,1 3775.718,887.948 L3814.504,782.346 A2362.500,2362.500 0.000 0,0 3797.384,776.133 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_40_Conservation-Score_5" class="Extracellular"/>
<path d="M3775.718,887.948 A2250.000,2250.000 40.000 0,1 3791.976,893.991 L3823.655,809.751 A2340.000,2340.000 0.000 0,0 3806.746,803.466 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_41_Conservation-Score_4" class="Extracellular"/>
<path d="M3791.976,893.991 A2250.000,2250.000 40.000 0,1 3808.187,900.159 L3856.678,774.168 A2385.000,2385.000 0.000 0,0 3839.495,767.630 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_42_Conservation-Score_6" class="Extracellular"/>
<path d="M3808.187,900.159 A2250.000,2250.000 40.000 0,1 3824.350,906.451 L3882.055,759.903 A2407.500,2407.500 0.000 0,0 3864.760,753.170 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_43_Conservation-Score_7" class="Extracellular"/>
<path d="M3824.350,906.451 A2250.000,2250.000 40.000 0,1 3840.465,912.868 L3907.702,745.898 A2430.000,2430.000 0.000 0,0 3890.298,738.967 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_44_Conservation-Score_8" class="Extracellular"/>
<path d="M3840.465,912.868 A2250.000,2250.000 40.000 0,1 3856.529,919.409 L3925.051,752.962 A2430.000,2430.000 0.000 0,0 3907.702,745.898 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_45_Conservation-Score_9" class="Extracellular"/>
<path d="M3856.529,919.409 A2250.000,2250.000 40.000 0,1 3872.542,926.074 L3933.620,780.899 A2407.500,2407.500 0.000 0,0 3916.486,773.768 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_46_Conservation-Score_7" class="Extracellular"/>
<path d="M3872.542,926.074 A2250.000,2250.000 40.000 0,1 3888.504,932.862 L3932.929,829.505 A2362.500,2362.500 0.000 0,0 3916.169,822.377 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_47_Conservation-Score_5" class="Extracellular"/>
<path d="M3888.504,932.862 A2250.000,2250.000 40.000 0,1 3904.412,939.772 L3976.765,774.954 A2430.000,2430.000 0.000 0,0 3959.584,767.490 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_48_Conservation-Score_8"/>
<path d="M3904.412,939.772 A2250.000,2250.000 40.000 0,1 3920.267,946.805 L3984.686,803.082 A2407.500,2407.500 0.000 0,0 3967.721,795.556 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_49_Conservation-Score_7"/>
<path d="M3920.267,946.805 A2250.000,2250.000 40.000 0,1 3936.067,953.960 L4010.953,790.277 A2430.000,2430.000 0.000 0,0 3993.889,782.550 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_50_Conservation-Score_9" class="Extracellular"/>
<path d="M3936.067,953.960 A2250.000,2250.000 40.000 0,1 3951.812,961.237 L4008.921,838.911 A2385.000,2385.000 0.000 0,0 3992.232,831.198 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_51_Conservation-Score_6" class="Extracellular"/>
<path d="M3951.812,961.237 A2250.000,2250.000 40.000 0,1 3967.500,968.635 L4025.550,846.753 A2385.000,2385.000 0.000 0,0 4008.921,838.911 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_52_Conservation-Score_6"/>
<path d="M3967.500,968.635 A2250.000,2250.000 40.000 0,1 3983.131,976.154 L4051.950,834.484 A2407.500,2407.500 0.000 0,0 4035.225,826.440 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_53_Conservation-Score_7"/>
<path d="M3983.131,976.154 A2250.000,2250.000 40.000 0,1 3998.703,983.793 L4028.664,923.306 A2317.500,2317.500 0.000 0,0 4012.625,915.438 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_54_Conservation-Score_2" class="Extracellular"/>
<path d="M3998.703,983.793 A2250.000,2250.000 40.000 0,1 4014.216,991.551 L4034.500,951.382 A2295.000,2295.000 0.000 0,0 4018.677,943.468 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_55_Conservation-Score_1"/>
<path d="M4014.216,991.551 A2250.000,2250.000 40.000 0,1 4029.668,999.429 L4070.855,919.406 A2340.000,2340.000 0.000 0,0 4054.784,911.213 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_56_Conservation-Score_4" class="Extracellular"/>
<path d="M4029.668,999.429 A2250.000,2250.000 40.000 0,1 4045.059,1007.426 L4107.763,887.872 A2385.000,2385.000 0.000 0,0 4091.448,879.395 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_57_Conservation-Score_6"/>
<path d="M4045.059,1007.426 A2250.000,2250.000 40.000 0,1 4060.389,1015.541 L4102.804,936.163 A2340.000,2340.000 0.000 0,0 4086.862,927.723 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_58_Conservation-Score_4"/>
<path d="M4060.389,1015.541 A2250.000,2250.000 40.000 0,1 4075.655,1023.775 L4150.951,885.439 A2407.500,2407.500 0.000 0,0 4134.616,876.629 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_59_Conservation-Score_7"/>
<path d="M4075.655,1023.775 A2250.000,2250.000 40.000 0,1 4090.857,1032.125 L4167.217,894.374 A2407.500,2407.500 0.000 0,0 4150.951,885.439 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_60_Conservation-Score_7" class="Extracellular"/>
<path d="M4090.857,1032.125 A2250.000,2250.000 40.000 0,1 4105.995,1040.593 L4161.294,942.623 A2362.500,2362.500 0.000 0,0 4145.400,933.732 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_61_Conservation-Score_5" class="Extracellular"/>
<path d="M4105.995,1040.593 A2250.000,2250.000 40.000 0,1 4121.066,1049.177 L4210.752,893.111 A2430.000,2430.000 0.000 0,0 4194.474,883.840 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_62_Conservation-Score_9" class="Extracellular"/>
<path d="M4121.066,1049.177 A2250.000,2250.000 40.000 0,1 4136.072,1057.877 L4215.597,921.928 A2407.500,2407.500 0.000 0,0 4199.541,912.619 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_63_Conservation-Score_7" class="Extracellular"/>
<path d="M4136.072,1057.877 A2250.000,2250.000 40.000 0,1 4151.009,1066.692 L4197.050,989.360 A2340.000,2340.000 0.000 0,0 4181.514,980.192 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_64_Conservation-Score_4" class="Extracellular"/>
<path d="M4151.009,1066.692 A2250.000,2250.000 40.000 0,1 4165.878,1075.623 L4247.490,940.916 A2407.500,2407.500 0.000 0,0 4231.580,931.361 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_65_Conservation-Score_7" class="Extracellular"/>
<path d="M4165.878,1075.623 A2250.000,2250.000 40.000 0,1 4180.678,1084.667 L4216.099,1027.207 A2317.500,2317.500 0.000 0,0 4200.855,1017.891 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_66_Conservation-Score_3"/>
<path d="M4180.678,1084.667 A2250.000,2250.000 40.000 0,1 4195.408,1093.826 L4219.316,1055.702 A2295.000,2295.000 0.000 0,0 4204.292,1046.361 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_67_Conservation-Score_1" class="Extracellular"/>
<path d="M4195.408,1093.826 A2250.000,2250.000 40.000 0,1 4210.067,1103.098 L4258.469,1027.222 A2340.000,2340.000 0.000 0,0 4243.224,1017.579 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_68_Conservation-Score_4" class="Extracellular"/>
<path d="M4210.067,1103.098 A2250.000,2250.000 40.000 0,1 4224.654,1112.482 L4261.393,1055.857 A2317.500,2317.500 0.000 0,0 4246.369,1046.191 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_69_Conservation-Score_2" class="Extracellular"/>
<path d="M4224.654,1112.482 A2250.000,2250.000 40.000 0,1 4239.168,1121.979 L4338.301,971.737 A2430.000,2430.000 0.000 0,0 4322.626,961.481 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_70_Conservation-Score_8" class="Extracellular"/>
<path d="M4239.168,1121.979 A2250.000,2250.000 40.000 0,1 4253.608,1131.587 L4291.216,1075.535 A2317.500,2317.500 0.000 0,0 4276.343,1065.638 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_71_Conservation-Score_3"/>
<path d="M4253.608,1131.587 A2250.000,2250.000 40.000 0,1 4267.974,1141.306 L4344.052,1029.785 A2385.000,2385.000 0.000 0,0 4328.824,1019.482 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_72_Conservation-Score_6"/>
<path d="M4267.974,1141.306 A2250.000,2250.000 40.000 0,1 4282.264,1151.136 L4333.555,1077.182 A2340.000,2340.000 0.000 0,0 4318.693,1066.959 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_73_Conservation-Score_4" class="Extracellular"/>
<path d="M4282.264,1151.136 A2250.000,2250.000 40.000 0,1 4296.479,1161.076 L4335.373,1105.908 A2317.500,2317.500 0.000 0,0 4320.732,1095.670 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_74_Conservation-Score_2"/>
<path d="M4296.479,1161.076 A2250.000,2250.000 40.000 0,1 4310.616,1171.125 L4349.935,1116.258 A2317.500,2317.500 0.000 0,0 4335.373,1105.908 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_75_Conservation-Score_3" class="Extracellular"/>
<path d="M4310.616,1171.125 A2250.000,2250.000 40.000 0,1 4324.676,1181.282 L4417.403,1053.972 A2407.500,2407.500 0.000 0,0 4402.359,1043.103 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_76_Conservation-Score_7"/>
<path d="M4324.676,1181.282 A2250.000,2250.000 40.000 0,1 4338.656,1191.548 L4405.589,1101.125 A2362.500,2362.500 0.000 0,0 4390.909,1090.346 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_77_Conservation-Score_5" class="Extracellular"/>
<path d="M4338.656,1191.548 A2250.000,2250.000 40.000 0,1 4352.557,1201.921 L4433.711,1094.036 A2385.000,2385.000 0.000 0,0 4418.976,1083.041 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_78_Conservation-Score_6" class="Extracellular"/>
<path d="M4352.557,1201.921 A2250.000,2250.000 40.000 0,1 4366.378,1212.401 L4393.706,1176.649 A2295.000,2295.000 0.000 0,0 4379.609,1165.959 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_79_Conservation-Score_1" class="Extracellular"/>
<path d="M4366.378,1212.401 A2250.000,2250.000 40.000 0,1 4380.118,1222.987 L4407.720,1187.447 A2295.000,2295.000 0.000 0,0 4393.706,1176.649 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_80_Conservation-Score_1"/>
<path d="M4380.118,1222.987 A2250.000,2250.000 40.000 0,1 4393.775,1233.679 L4421.651,1198.352 A2295.000,2295.000 0.000 0,0 4407.720,1187.447 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_81_Conservation-Score_1"/>
<path d="M4393.775,1233.679 A2250.000,2250.000 40.000 0,1 4407.350,1244.476 L4421.424,1226.920 A2272.500,2272.500 0.000 0,0 4407.713,1216.016 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_82_Conservation-Score_0"/>
<path d="M4407.350,1244.476 A2250.000,2250.000 40.000 0,1 4420.841,1255.377 L4463.466,1203.038 A2317.500,2317.500 0.000 0,0 4449.571,1191.810 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_83_Conservation-Score_2" class="Extracellular"/>
<path d="M4420.841,1255.377 A2250.000,2250.000 40.000 0,1 4434.248,1266.381 L4462.933,1231.709 A2295.000,2295.000 0.000 0,0 4449.258,1220.484 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_84_Conservation-Score_1" class="Extracellular"/>
<path d="M4434.248,1266.381 A2250.000,2250.000 40.000 0,1 4447.569,1277.489 L4490.996,1225.814 A2317.500,2317.500 0.000 0,0 4477.275,1214.373 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_85_Conservation-Score_2"/>
<path d="M4447.569,1277.489 A2250.000,2250.000 40.000 0,1 4460.805,1288.699 L4475.413,1271.586 A2272.500,2272.500 0.000 0,0 4462.045,1260.264 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_86_Conservation-Score_0"/>
<path d="M4460.805,1288.699 A2250.000,2250.000 40.000 0,1 4473.953,1300.011 L4518.172,1249.012 A2317.500,2317.500 0.000 0,0 4504.629,1237.360 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_87_Conservation-Score_3"/>
<path d="M4473.953,1300.011 A2250.000,2250.000 40.000 0,1 4487.014,1311.424 L4561.365,1226.995 A2362.500,2362.500 0.000 0,0 4547.651,1215.012 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_88_Conservation-Score_5" class="Extracellular"/>
<path d="M4487.014,1311.424 A2250.000,2250.000 40.000 0,1 4499.987,1322.937 L4574.986,1239.084 A2362.500,2362.500 0.000 0,0 4561.365,1226.995 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_89_Conservation-Score_5" class="Extracellular"/>
<path d="M4499.987,1322.937 A2250.000,2250.000 40.000 0,1 4512.870,1334.550 L4618.771,1217.969 A2407.500,2407.500 0.000 0,0 4604.986,1205.543 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_90_Conservation-Score_7"/>
<path d="M4512.870,1334.550 A2250.000,2250.000 40.000 0,1 4525.664,1346.262 L4556.177,1313.187 A2295.000,2295.000 0.000 0,0 4543.128,1301.241 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_91_Conservation-Score_1"/>
<path d="M4525.664,1346.262 A2250.000,2250.000 40.000 0,1 4538.367,1358.072 L4599.902,1292.395 A2340.000,2340.000 0.000 0,0 4586.691,1280.113 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_92_Conservation-Score_4" class="Extracellular"/>
<path d="M4538.367,1358.072 A2250.000,2250.000 40.000 0,1 4550.979,1369.980 L4628.527,1288.479 A2362.500,2362.500 0.000 0,0 4615.285,1275.976 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_93_Conservation-Score_5" class="Extracellular"/>
<path d="M4550.979,1369.980 A2250.000,2250.000 40.000 0,1 4563.498,1381.984 L4688.578,1252.543 A2430.000,2430.000 0.000 0,0 4675.057,1239.578 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_94_Conservation-Score_9" class="Extracellular"/>
<path d="M4563.498,1381.984 A2250.000,2250.000 40.000 0,1 4575.924,1394.085 L4623.202,1345.908 A2317.500,2317.500 0.000 0,0 4610.403,1333.444 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_95_Conservation-Score_3" class="Extracellular"/>
<path d="M4575.924,1394.085 A2250.000,2250.000 40.000 0,1 4588.257,1406.281 L4667.670,1326.595 A2362.500,2362.500 0.000 0,0 4654.721,1313.789 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_96_Conservation-Score_5"/>
<path d="M4588.257,1406.281 A2250.000,2250.000 40.000 0,1 4600.496,1418.572 L4680.520,1339.501 A2362.500,2362.500 0.000 0,0 4667.670,1326.595 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_97_Conservation-Score_5"/>
<path d="M4600.496,1418.572 A2250.000,2250.000 40.000 0,1 4612.639,1430.957 L4709.397,1336.814 A2385.000,2385.000 0.000 0,0 4696.525,1323.686 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_98_Conservation-Score_6"/>
<path d="M4612.639,1430.957 A2250.000,2250.000 40.000 0,1 4624.686,1443.435 L4689.674,1381.172 A2340.000,2340.000 0.000 0,0 4677.144,1368.195 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_99_Conservation-Score_4"/>
<path d="M4624.686,1443.435 A2250.000,2250.000 40.000 0,1 4636.637,1456.006 L4718.469,1378.806 A2362.500,2362.500 0.000 0,0 4705.921,1365.607 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_100_Conservation-Score_5" class="Extracellular"/>
<path d="M4636.637,1456.006 A2250.000,2250.000 40.000 0,1 4648.491,1468.668 L4747.400,1376.788 A2385.000,2385.000 0.000 0,0 4734.835,1363.366 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_101_Conservation-Score_6" class="Extracellular"/>
<path d="M4648.491,1468.668 A2250.000,2250.000 40.000 0,1 4660.247,1481.421 L4726.656,1420.678 A2340.000,2340.000 0.000 0,0 4714.430,1407.415 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_102_Conservation-Score_4" class="Extracellular"/>
<path d="M4660.247,1481.421 A2250.000,2250.000 40.000 0,1 4671.904,1494.265 L4805.656,1373.806 A2430.000,2430.000 0.000 0,0 4793.066,1359.935 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_103_Conservation-Score_9" class="Extracellular"/>
<path d="M4671.904,1494.265 A2250.000,2250.000 40.000 0,1 4683.461,1507.198 L4851.807,1357.918 A2475.000,2475.000 0.000 0,0 4839.094,1343.691 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_104_Conservation-Score_11" class="Extracellular"/>
<path d="M4683.461,1507.198 A2250.000,2250.000 40.000 0,1 4694.919,1520.220 L4830.512,1401.837 A2430.000,2430.000 0.000 0,0 4818.138,1387.774 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_105_Conservation-Score_8"/>
<path d="M4694.919,1520.220 A2250.000,2250.000 40.000 0,1 4706.276,1533.329 L4842.778,1415.996 A2430.000,2430.000 0.000 0,0 4830.512,1401.837 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_106_Conservation-Score_8"/>
<path d="M4706.276,1533.329 A2250.000,2250.000 40.000 0,1 4717.531,1546.526 L4837.759,1444.783 A2407.500,2407.500 0.000 0,0 4825.715,1430.662 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_107_Conservation-Score_7" class="Extracellular"/>
<path d="M4717.531,1546.526 A2250.000,2250.000 40.000 0,1 4728.685,1559.809 L4866.980,1444.594 A2430.000,2430.000 0.000 0,0 4854.934,1430.248 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_108_Conservation-Score_8"/>
<path d="M4728.685,1559.809 A2250.000,2250.000 40.000 0,1 4739.735,1573.178 L4878.914,1459.032 A2430.000,2430.000 0.000 0,0 4866.980,1444.594 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_109_Conservation-Score_8"/>
<path d="M4739.735,1573.178 A2250.000,2250.000 40.000 0,1 4750.683,1586.632 L4803.203,1544.231 A2317.500,2317.500 0.000 0,0 4791.928,1530.374 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_110_Conservation-Score_2" class="Extracellular"/>
<path d="M4750.683,1586.632 A2250.000,2250.000 40.000 0,1 4761.526,1600.169 L4884.833,1502.181 A2407.500,2407.500 0.000 0,0 4873.231,1487.696 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_111_Conservation-Score_7" class="Extracellular"/>
<path d="M4761.526,1600.169 A2250.000,2250.000 40.000 0,1 4772.265,1613.790 L4949.491,1475.169 A2475.000,2475.000 0.000 0,0 4937.679,1460.186 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_112_Conservation-Score_11"/>
<path d="M4772.265,1613.790 A2250.000,2250.000 40.000 0,1 4782.898,1627.493 L4889.872,1545.143 A2385.000,2385.000 0.000 0,0 4878.601,1530.618 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_113_Conservation-Score_6"/>
<path d="M4782.898,1627.493 A2250.000,2250.000 40.000 0,1 4793.425,1641.278 L4883.097,1573.342 A2362.500,2362.500 0.000 0,0 4872.043,1558.868 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_114_Conservation-Score_5"/>
<path d="M4793.425,1641.278 A2250.000,2250.000 40.000 0,1 4803.846,1655.144 L4912.077,1574.452 A2385.000,2385.000 0.000 0,0 4901.031,1559.755 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_115_Conservation-Score_6" class="Extracellular"/>
<path d="M4803.846,1655.144 A2250.000,2250.000 40.000 0,1 4814.160,1669.089 L4977.434,1549.307 A2452.500,2452.500 0.000 0,0 4966.192,1534.106 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_116_Conservation-Score_10"/>
<path d="M4814.160,1669.089 A2250.000,2250.000 40.000 0,1 4824.366,1683.113 L4970.315,1577.762 A2430.000,2430.000 0.000 0,0 4959.293,1562.616 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_117_Conservation-Score_9"/>
<path d="M4824.366,1683.113 A2250.000,2250.000 40.000 0,1 4834.463,1697.216 L4962.875,1606.021 A2407.500,2407.500 0.000 0,0 4952.071,1590.931 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_118_Conservation-Score_7"/>
<path d="M4834.463,1697.216 A2250.000,2250.000 40.000 0,1 4844.451,1711.396 L4992.007,1608.308 A2430.000,2430.000 0.000 0,0 4981.220,1592.993 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_119_Conservation-Score_9" class="Extracellular"/>
<path d="M4844.451,1711.396 A2250.000,2250.000 40.000 0,1 4854.330,1725.653 L4965.590,1649.192 A2385.000,2385.000 0.000 0,0 4955.118,1634.080 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_120_Conservation-Score_6" class="Extracellular"/>
<path d="M4854.330,1725.653 A2250.000,2250.000 40.000 0,1 4864.099,1739.985 L5013.226,1639.184 A2430.000,2430.000 0.000 0,0 5002.676,1623.705 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_121_Conservation-Score_9"/>
<path d="M4864.099,1739.985 A2250.000,2250.000 40.000 0,1 4873.756,1754.393 L4929.969,1717.025 A2317.500,2317.500 0.000 0,0 4920.021,1702.185 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_122_Conservation-Score_3"/>
<path d="M4873.756,1754.393 A2250.000,2250.000 40.000 0,1 4883.303,1768.874 L5033.967,1670.384 A2430.000,2430.000 0.000 0,0 5023.657,1654.744 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_123_Conservation-Score_8"/>
<path d="M4883.303,1768.874 A2250.000,2250.000 40.000 0,1 4892.737,1783.429 L5006.301,1710.434 A2385.000,2385.000 0.000 0,0 4996.301,1695.007 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_124_Conservation-Score_6" class="Extracellular"/>
<path d="M4892.737,1783.429 A2250.000,2250.000 40.000 0,1 4902.059,1798.055 L5035.203,1713.919 A2407.500,2407.500 0.000 0,0 5025.229,1698.269 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_125_Conservation-Score_7"/>
<path d="M4902.059,1798.055 A2250.000,2250.000 40.000 0,1 4911.268,1812.754 L5083.282,1705.901 A2452.500,2452.500 0.000 0,0 5073.245,1689.880 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_126_Conservation-Score_10"/>
<path d="M4911.268,1812.754 A2250.000,2250.000 40.000 0,1 4920.364,1827.522 L5016.382,1768.899 A2362.500,2362.500 0.000 0,0 5006.832,1753.391 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_127_Conservation-Score_5" class="Extracellular"/>
<path d="M4920.364,1827.522 A2250.000,2250.000 40.000 0,1 4929.345,1842.361 L5025.812,1784.479 A2362.500,2362.500 0.000 0,0 5016.382,1768.899 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_128_Conservation-Score_5" class="Extracellular"/>
<path d="M4929.345,1842.361 A2250.000,2250.000 40.000 0,1 4938.212,1857.268 L5035.122,1800.132 A2362.500,2362.500 0.000 0,0 5025.812,1784.479 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_129_Conservation-Score_5" class="Extracellular"/>
<path d="M4938.212,1857.268 A2250.000,2250.000 40.000 0,1 4946.963,1872.243 L5024.842,1827.133 A2340.000,2340.000 0.000 0,0 5015.740,1811.559 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_130_Conservation-Score_4"/>
<path d="M4946.963,1872.243 A2250.000,2250.000 40.000 0,1 4955.599,1887.286 L5033.823,1842.777 A2340.000,2340.000 0.000 0,0 5024.842,1827.133 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_131_Conservation-Score_4"/>
<path d="M4955.599,1887.286 A2250.000,2250.000 40.000 0,1 4964.118,1902.394 L5023.042,1869.466 A2317.500,2317.500 0.000 0,0 5014.267,1853.904 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_132_Conservation-Score_2"/>
<path d="M4964.118,1902.394 A2250.000,2250.000 40.000 0,1 4972.521,1917.567 L5090.872,1852.621 A2385.000,2385.000 0.000 0,0 5081.965,1836.537 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_133_Conservation-Score_6"/>
<path d="M4972.521,1917.567 A2250.000,2250.000 40.000 0,1 4980.807,1932.805 L5119.463,1858.102 A2407.500,2407.500 0.000 0,0 5110.598,1841.797 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_134_Conservation-Score_7" class="Extracellular"/>
<path d="M4980.807,1932.805 A2250.000,2250.000 40.000 0,1 4988.975,1948.107 L5088.423,1895.512 A2362.500,2362.500 0.000 0,0 5079.847,1879.445 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_135_Conservation-Score_5"/>
<path d="M4988.975,1948.107 A2250.000,2250.000 40.000 0,1 4997.024,1963.470 L5076.905,1922.009 A2340.000,2340.000 0.000 0,0 5068.534,1906.031 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_136_Conservation-Score_4"/>
<path d="M4997.024,1963.470 A2250.000,2250.000 40.000 0,1 5004.955,1978.896 L5045.054,1958.474 A2295.000,2295.000 0.000 0,0 5036.965,1942.740 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_137_Conservation-Score_1"/>
<path d="M5004.955,1978.896 A2250.000,2250.000 40.000 0,1 5012.767,1994.382 L5153.661,1923.988 A2407.500,2407.500 0.000 0,0 5145.302,1907.418 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_138_Conservation-Score_7"/>
<path d="M5012.767,1994.382 A2250.000,2250.000 40.000 0,1 5020.459,2009.928 L5182.096,1930.722 A2430.000,2430.000 0.000 0,0 5173.789,1913.932 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_139_Conservation-Score_8" class="Extracellular"/>
<path d="M5020.459,2009.928 A2250.000,2250.000 40.000 0,1 5028.032,2025.532 L5088.873,1996.298 A2317.500,2317.500 0.000 0,0 5081.073,1980.225 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_140_Conservation-Score_3"/>
<path d="M5028.032,2025.532 A2250.000,2250.000 40.000 0,1 5035.483,2041.195 L5137.258,1993.255 A2362.500,2362.500 0.000 0,0 5129.433,1976.809 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_141_Conservation-Score_5" class="Extracellular"/>
<path d="M5035.483,2041.195 A2250.000,2250.000 40.000 0,1 5042.814,2056.914 L5206.239,1981.467 A2430.000,2430.000 0.000 0,0 5198.322,1964.490 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_142_Conservation-Score_8"/>
<path d="M5042.814,2056.914 A2250.000,2250.000 40.000 0,1 5050.023,2072.690 L5070.524,2063.417 A2272.500,2272.500 0.000 0,0 5063.242,2047.483 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_143_Conservation-Score_0" class="Extracellular"/>
<path d="M5050.023,2072.690 A2250.000,2250.000 40.000 0,1 5057.111,2088.521 L5098.253,2070.291 A2295.000,2295.000 0.000 0,0 5091.024,2054.144 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_144_Conservation-Score_1" class="Extracellular"/>
<path d="M5057.111,2088.521 A2250.000,2250.000 40.000 0,1 5064.076,2104.405 L5084.717,2095.450 A2272.500,2272.500 0.000 0,0 5077.682,2079.406 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_145_Conservation-Score_0"/>
<path d="M5064.076,2104.405 A2250.000,2250.000 40.000 0,1 5070.919,2120.344 L5174.465,2076.361 A2362.500,2362.500 0.000 0,0 5167.280,2059.626 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_146_Conservation-Score_5" class="Extracellular"/>
<path d="M5070.919,2120.344 A2250.000,2250.000 40.000 0,1 5077.638,2136.334 L5243.849,2067.241 A2430.000,2430.000 0.000 0,0 5236.592,2049.971 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_147_Conservation-Score_8"/>
<path d="M5077.638,2136.334 A2250.000,2250.000 40.000 0,1 5084.234,2152.376 L5146.761,2126.947 A2317.500,2317.500 0.000 0,0 5139.967,2110.424 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_148_Conservation-Score_3" class="Extracellular"/>
<path d="M5084.234,2152.376 A2250.000,2250.000 40.000 0,1 5090.707,2168.468 L5153.428,2143.522 A2317.500,2317.500 0.000 0,0 5146.761,2126.947 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_149_Conservation-Score_2"/>
<path d="M5090.707,2168.468 A2250.000,2250.000 40.000 0,1 5097.055,2184.609 L5138.996,2168.301 A2295.000,2295.000 0.000 0,0 5132.521,2151.837 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_150_Conservation-Score_1" class="Extracellular"/>
<path d="M5097.055,2184.609 A2250.000,2250.000 40.000 0,1 5103.278,2200.799 L5145.343,2184.815 A2295.000,2295.000 0.000 0,0 5138.996,2168.301 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_151_Conservation-Score_1"/>
<path d="M5103.278,2200.799 A2250.000,2250.000 40.000 0,1 5109.376,2217.036 L5151.564,2201.377 A2295.000,2295.000 0.000 0,0 5145.343,2184.815 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_152_Conservation-Score_1"/>
<path d="M5109.376,2217.036 A2250.000,2250.000 40.000 0,1 5115.349,2233.320 L5199.963,2202.653 A2340.000,2340.000 0.000 0,0 5193.751,2185.718 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_153_Conservation-Score_4"/>
<path d="M5115.349,2233.320 A2250.000,2250.000 40.000 0,1 5121.197,2249.650 L5248.468,2204.629 A2385.000,2385.000 0.000 0,0 5242.270,2187.320 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_154_Conservation-Score_6"/>
<path d="M5121.197,2249.650 A2250.000,2250.000 40.000 0,1 5126.918,2266.024 L5233.264,2229.325 A2362.500,2362.500 0.000 0,0 5227.256,2212.132 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_155_Conservation-Score_5" class="Extracellular"/>
<path d="M5126.918,2266.024 A2250.000,2250.000 40.000 0,1 5132.513,2282.442 L5217.813,2253.739 A2340.000,2340.000 0.000 0,0 5211.994,2236.665 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_156_Conservation-Score_4" class="Extracellular"/>
<path d="M5132.513,2282.442 A2250.000,2250.000 40.000 0,1 5137.981,2298.902 L5223.500,2270.858 A2340.000,2340.000 0.000 0,0 5217.813,2253.739 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_157_Conservation-Score_4" class="Extracellular"/>
<path d="M5137.981,2298.902 A2250.000,2250.000 40.000 0,1 5143.322,2315.404 L5271.921,2274.328 A2385.000,2385.000 0.000 0,0 5266.260,2256.836 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_158_Conservation-Score_6" class="Extracellular"/>
<path d="M5143.322,2315.404 A2250.000,2250.000 40.000 0,1 5148.536,2331.947 L5320.418,2278.503 A2430.000,2430.000 0.000 0,0 5314.788,2260.636 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_159_Conservation-Score_9"/>
<path d="M5148.536,2331.947 A2250.000,2250.000 40.000 0,1 5153.622,2348.529 L5218.230,2328.985 A2317.500,2317.500 0.000 0,0 5212.992,2311.905 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_160_Conservation-Score_2" class="Extracellular"/>
<path d="M5153.622,2348.529 A2250.000,2250.000 40.000 0,1 5158.580,2365.150 L5223.337,2346.105 A2317.500,2317.500 0.000 0,0 5218.230,2328.985 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_161_Conservation-Score_3" class="Extracellular"/>
<path d="M5158.580,2365.150 A2250.000,2250.000 40.000 0,1 5163.409,2381.809 L5379.750,2319.990 A2475.000,2475.000 0.000 0,0 5374.438,2301.665 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_162_Conservation-Score_11" class="Extracellular"/>
<path d="M5163.409,2381.809 A2250.000,2250.000 40.000 0,1 5168.111,2398.505 L5254.835,2374.445 A2340.000,2340.000 0.000 0,0 5249.946,2357.082 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_163_Conservation-Score_4" class="Extracellular"/>
<path d="M5168.111,2398.505 A2250.000,2250.000 40.000 0,1 5172.683,2415.236 L5237.863,2397.693 A2317.500,2317.500 0.000 0,0 5233.154,2380.460 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_164_Conservation-Score_3"/>
<path d="M5172.683,2415.236 A2250.000,2250.000 40.000 0,1 5177.126,2432.002 L5307.754,2397.922 A2385.000,2385.000 0.000 0,0 5303.044,2380.150 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_165_Conservation-Score_6"/>
<path d="M5177.126,2432.002 A2250.000,2250.000 40.000 0,1 5181.440,2448.802 L5312.326,2415.730 A2385.000,2385.000 0.000 0,0 5307.754,2397.922 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_166_Conservation-Score_6"/>
<path d="M5181.440,2448.802 A2250.000,2250.000 40.000 0,1 5185.624,2465.635 L5273.049,2444.260 A2340.000,2340.000 0.000 0,0 5268.698,2426.754 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_167_Conservation-Score_4" class="Extracellular"/>
<path d="M5185.624,2465.635 A2250.000,2250.000 40.000 0,1 5189.679,2482.499 L5321.059,2451.449 A2385.000,2385.000 0.000 0,0 5316.762,2433.573 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_168_Conservation-Score_6"/>
<path d="M5189.679,2482.499 A2250.000,2250.000 40.000 0,1 5193.603,2499.394 L5325.219,2469.358 A2385.000,2385.000 0.000 0,0 5321.059,2451.449 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_169_Conservation-Score_6" class="Extracellular"/>
<path d="M5193.603,2499.394 A2250.000,2250.000 40.000 0,1 5197.397,2516.319 L5285.293,2496.972 A2340.000,2340.000 0.000 0,0 5281.347,2479.370 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_170_Conservation-Score_4" class="Extracellular"/>
<path d="M5197.397,2516.319 A2250.000,2250.000 40.000 0,1 5201.060,2533.272 L5355.134,2500.601 A2407.500,2407.500 0.000 0,0 5351.215,2482.461 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_171_Conservation-Score_7" class="Extracellular"/>
<path d="M5201.060,2533.272 A2250.000,2250.000 40.000 0,1 5204.593,2550.254 L5314.822,2527.766 A2362.500,2362.500 0.000 0,0 5311.113,2509.936 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_172_Conservation-Score_5" class="Extracellular"/>
<path d="M5204.593,2550.254 A2250.000,2250.000 40.000 0,1 5207.994,2567.262 L5274.234,2554.280 A2317.500,2317.500 0.000 0,0 5270.730,2536.761 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_173_Conservation-Score_2" class="Extracellular"/>
<path d="M5207.994,2567.262 A2250.000,2250.000 40.000 0,1 5211.264,2584.295 L5432.391,2542.725 A2475.000,2475.000 0.000 0,0 5428.793,2523.988 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_174_Conservation-Score_11" class="Extracellular"/>
<path d="M5211.264,2584.295 A2250.000,2250.000 40.000 0,1 5214.403,2601.354 L5435.843,2561.489 A2475.000,2475.000 0.000 0,0 5432.391,2542.725 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_175_Conservation-Score_11"/>
<path d="M5214.403,2601.354 A2250.000,2250.000 40.000 0,1 5217.410,2618.436 L5372.629,2591.727 A2407.500,2407.500 0.000 0,0 5369.411,2573.449 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_176_Conservation-Score_7"/>
<path d="M5217.410,2618.436 A2250.000,2250.000 40.000 0,1 5220.286,2635.541 L5397.909,2606.384 A2430.000,2430.000 0.000 0,0 5394.803,2587.911 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_177_Conservation-Score_8"/>
<path d="M5220.286,2635.541 A2250.000,2250.000 40.000 0,1 5223.029,2652.667 L5311.951,2638.774 A2340.000,2340.000 0.000 0,0 5309.097,2620.963 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_178_Conservation-Score_4"/>
<path d="M5223.029,2652.667 A2250.000,2250.000 40.000 0,1 5225.641,2669.815 L5359.179,2650.003 A2385.000,2385.000 0.000 0,0 5356.411,2631.827 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_179_Conservation-Score_6"/>
<path d="M5225.641,2669.815 A2250.000,2250.000 40.000 0,1 5228.120,2686.981 L5384.089,2665.070 A2407.500,2407.500 0.000 0,0 5381.436,2646.702 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_180_Conservation-Score_7"/>
<path d="M5228.120,2686.981 A2250.000,2250.000 40.000 0,1 5230.467,2704.167 L5319.686,2692.333 A2340.000,2340.000 0.000 0,0 5317.245,2674.461 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_181_Conservation-Score_4"/>
<path d="M5230.467,2704.167 A2250.000,2250.000 40.000 0,1 5232.681,2721.370 L5411.296,2699.079 A2430.000,2430.000 0.000 0,0 5408.904,2680.500 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_182_Conservation-Score_8"/>
<path d="M5232.681,2721.370 A2250.000,2250.000 40.000 0,1 5234.763,2738.589 L5368.848,2722.904 A2385.000,2385.000 0.000 0,0 5366.642,2704.652 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_183_Conservation-Score_6"/>
<path d="M5234.763,2738.589 A2250.000,2250.000 40.000 0,1 5236.711,2755.824 L5303.813,2748.499 A2317.500,2317.500 0.000 0,0 5301.806,2730.747 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_184_Conservation-Score_3" class="Extracellular"/>
<path d="M5236.711,2755.824 A2250.000,2250.000 40.000 0,1 5238.527,2773.074 L5305.683,2766.266 A2317.500,2317.500 0.000 0,0 5303.813,2748.499 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_185_Conservation-Score_2"/>
<path d="M5238.527,2773.074 A2250.000,2250.000 40.000 0,1 5240.210,2790.337 L5464.231,2769.370 A2475.000,2475.000 0.000 0,0 5462.380,2750.381 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_186_Conservation-Score_11"/>
<path d="M5240.210,2790.337 A2250.000,2250.000 40.000 0,1 5241.760,2807.612 L5398.683,2794.145 A2407.500,2407.500 0.000 0,0 5397.025,2775.660 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_187_Conservation-Score_7" class="Extracellular"/>
<path d="M5241.760,2807.612 A2250.000,2250.000 40.000 0,1 5243.176,2824.899 L5400.199,2812.642 A2407.500,2407.500 0.000 0,0 5398.683,2794.145 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_188_Conservation-Score_7" class="Extracellular"/>
<path d="M5243.176,2824.899 A2250.000,2250.000 40.000 0,1 5244.459,2842.196 L5334.238,2835.884 A2340.000,2340.000 0.000 0,0 5332.903,2817.895 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_189_Conservation-Score_4" class="Extracellular"/>
<path d="M5244.459,2842.196 A2250.000,2250.000 40.000 0,1 5245.609,2859.503 L5470.170,2845.453 A2475.000,2475.000 0.000 0,0 5468.905,2826.416 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_190_Conservation-Score_11"/>
<path d="M5245.609,2859.503 A2250.000,2250.000 40.000 0,1 5246.626,2876.818 L5336.491,2871.891 A2340.000,2340.000 0.000 0,0 5335.434,2853.883 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_191_Conservation-Score_4" class="Extracellular"/>
<path d="M5246.626,2876.818 A2250.000,2250.000 40.000 0,1 5247.508,2894.140 L5404.834,2886.730 A2407.500,2407.500 0.000 0,0 5403.889,2868.195 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_192_Conservation-Score_7"/>
<path d="M5247.508,2894.140 A2250.000,2250.000 40.000 0,1 5248.258,2911.469 L5338.188,2907.928 A2340.000,2340.000 0.000 0,0 5337.409,2889.906 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_193_Conservation-Score_4" class="Extracellular"/>
<path d="M5248.258,2911.469 A2250.000,2250.000 40.000 0,1 5248.873,2928.803 L5293.851,2927.379 A2295.000,2295.000 0.000 0,0 5293.223,2909.698 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_194_Conservation-Score_1" class="Extracellular"/>
<path d="M5248.873,2928.803 A2250.000,2250.000 40.000 0,1 5249.355,2946.141 L5316.836,2944.525 A2317.500,2317.500 0.000 0,0 5316.339,2926.667 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_195_Conservation-Score_3"/>
<path d="M5249.355,2946.141 A2250.000,2250.000 40.000 0,1 5249.704,2963.482 L5384.686,2961.291 A2385.000,2385.000 0.000 0,0 5384.317,2942.910 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_196_Conservation-Score_6" class="Extracellular"/>
<path d="M5249.704,2963.482 A2250.000,2250.000 40.000 0,1 5249.918,2980.826 L5362.414,2979.867 A2362.500,2362.500 0.000 0,0 5362.189,2961.657 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_197_Conservation-Score_5" class="Extracellular"/>
<path d="M5249.918,2980.826 A2250.000,2250.000 40.000 0,1 5249.999,2998.171 L5384.999,2998.061 A2385.000,2385.000 0.000 0,0 5384.913,2979.676 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_198_Conservation-Score_6"/>
<path d="M5249.999,2998.171 A2250.000,2250.000 40.000 0,1 5249.947,3015.515 L5407.443,3016.601 A2407.500,2407.500 0.000 0,0 5407.499,2998.043 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_199_Conservation-Score_7" class="Extracellular"/>
<path d="M5249.947,3015.515 A2250.000,2250.000 40.000 0,1 5249.760,3032.859 L5407.243,3035.159 A2407.500,2407.500 0.000 0,0 5407.443,3016.601 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_200_Conservation-Score_7" class="Extracellular"/>
<path d="M5249.760,3032.859 A2250.000,2250.000 40.000 0,1 5249.440,3050.201 L5339.417,3052.209 A2340.000,2340.000 0.000 0,0 5339.750,3034.174 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_201_Conservation-Score_4" class="Extracellular"/>
<path d="M5249.440,3050.201 A2250.000,2250.000 40.000 0,1 5248.986,3067.540 L5406.415,3072.268 A2407.500,2407.500 0.000 0,0 5406.901,3053.715 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_202_Conservation-Score_7"/>
<path d="M5248.986,3067.540 A2250.000,2250.000 40.000 0,1 5248.399,3084.875 L5383.303,3089.967 A2385.000,2385.000 0.000 0,0 5383.925,3071.592 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_203_Conservation-Score_6" class="Extracellular"/>
<path d="M5248.399,3084.875 A2250.000,2250.000 40.000 0,1 5247.678,3102.205 L5337.585,3106.293 A2340.000,2340.000 0.000 0,0 5338.335,3088.270 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_204_Conservation-Score_4" class="Extracellular"/>
<path d="M5247.678,3102.205 A2250.000,2250.000 40.000 0,1 5246.823,3119.529 L5314.228,3123.114 A2317.500,2317.500 0.000 0,0 5315.108,3105.271 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_205_Conservation-Score_3" class="Extracellular"/>
<path d="M5246.823,3119.529 A2250.000,2250.000 40.000 0,1 5245.835,3136.845 L5335.668,3142.319 A2340.000,2340.000 0.000 0,0 5336.696,3124.310 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_206_Conservation-Score_4"/>
<path d="M5245.835,3136.845 A2250.000,2250.000 40.000 0,1 5244.713,3154.154 L5312.054,3158.778 A2317.500,2317.500 0.000 0,0 5313.210,3140.951 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_207_Conservation-Score_3" class="Extracellular"/>
<path d="M5244.713,3154.154 A2250.000,2250.000 40.000 0,1 5243.458,3171.453 L5333.196,3178.311 A2340.000,2340.000 0.000 0,0 5334.502,3160.320 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_208_Conservation-Score_4"/>
<path d="M5243.458,3171.453 A2250.000,2250.000 40.000 0,1 5242.070,3188.742 L5309.332,3194.405 A2317.500,2317.500 0.000 0,0 5310.762,3176.597 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_209_Conservation-Score_3"/>
<path d="M5242.070,3188.742 A2250.000,2250.000 40.000 0,1 5240.548,3206.020 L5352.575,3216.321 A2362.500,2362.500 0.000 0,0 5354.173,3198.179 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_210_Conservation-Score_5" class="Extracellular"/>
<path d="M5240.548,3206.020 A2250.000,2250.000 40.000 0,1 5238.893,3223.286 L5350.838,3234.450 A2362.500,2362.500 0.000 0,0 5352.575,3216.321 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_211_Conservation-Score_5"/>
<path d="M5238.893,3223.286 A2250.000,2250.000 40.000 0,1 5237.106,3240.539 L5348.961,3252.565 A2362.500,2362.500 0.000 0,0 5350.838,3234.450 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_212_Conservation-Score_5" class="Extracellular"/>
<path d="M5237.106,3240.539 A2250.000,2250.000 40.000 0,1 5235.185,3257.777 L5324.592,3268.088 A2340.000,2340.000 0.000 0,0 5326.590,3250.160 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_213_Conservation-Score_4"/>
<path d="M5235.185,3257.777 A2250.000,2250.000 40.000 0,1 5233.131,3275.000 L5344.788,3288.750 A2362.500,2362.500 0.000 0,0 5346.944,3270.666 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_214_Conservation-Score_5"/>
<path d="M5233.131,3275.000 A2250.000,2250.000 40.000 0,1 5230.945,3292.206 L5454.040,3321.427 A2475.000,2475.000 0.000 0,0 5456.444,3302.499 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_215_Conservation-Score_11"/>
<path d="M5230.945,3292.206 A2250.000,2250.000 40.000 0,1 5228.626,3309.395 L5340.057,3324.865 A2362.500,2362.500 0.000 0,0 5342.492,3306.816 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_216_Conservation-Score_5"/>
<path d="M5228.626,3309.395 A2250.000,2250.000 40.000 0,1 5226.175,3326.566 L5404.269,3352.691 A2430.000,2430.000 0.000 0,0 5406.916,3334.147 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_217_Conservation-Score_9"/>
<path d="M5226.175,3326.566 A2250.000,2250.000 40.000 0,1 5223.591,3343.717 L5379.243,3367.778 A2407.500,2407.500 0.000 0,0 5382.007,3349.426 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_218_Conservation-Score_7"/>
<path d="M5223.591,3343.717 A2250.000,2250.000 40.000 0,1 5220.876,3360.848 L5331.919,3378.891 A2362.500,2362.500 0.000 0,0 5334.771,3360.903 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_219_Conservation-Score_5"/>
<path d="M5220.876,3360.848 A2250.000,2250.000 40.000 0,1 5218.028,3377.958 L5306.749,3393.076 A2340.000,2340.000 0.000 0,0 5309.711,3375.282 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_220_Conservation-Score_4" class="Extracellular"/>
<path d="M5218.028,3377.958 A2250.000,2250.000 40.000 0,1 5215.048,3395.045 L5347.951,3418.747 A2385.000,2385.000 0.000 0,0 5351.110,3400.635 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_221_Conservation-Score_6" class="Extracellular"/>
<path d="M5215.048,3395.045 A2250.000,2250.000 40.000 0,1 5211.937,3412.108 L5322.534,3432.714 A2362.500,2362.500 0.000 0,0 5325.801,3414.797 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_222_Conservation-Score_5" class="Extracellular"/>
<path d="M5211.937,3412.108 A2250.000,2250.000 40.000 0,1 5208.695,3429.147 L5252.869,3437.730 A2295.000,2295.000 0.000 0,0 5256.176,3420.350 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_223_Conservation-Score_1"/>
<path d="M5208.695,3429.147 A2250.000,2250.000 40.000 0,1 5205.321,3446.161 L5249.427,3455.084 A2295.000,2295.000 0.000 0,0 5252.869,3437.730 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_224_Conservation-Score_1" class="Extracellular"/>
<path d="M5205.321,3446.161 A2250.000,2250.000 40.000 0,1 5201.816,3463.148 L5245.852,3472.411 A2295.000,2295.000 0.000 0,0 5249.427,3455.084 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_225_Conservation-Score_1"/>
<path d="M5201.816,3463.148 A2250.000,2250.000 40.000 0,1 5198.180,3480.107 L5220.162,3484.908 A2272.500,2272.500 0.000 0,0 5223.834,3467.779 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_226_Conservation-Score_0" class="Extracellular"/>
<path d="M5198.180,3480.107 A2250.000,2250.000 40.000 0,1 5194.414,3497.038 L5216.358,3502.009 A2272.500,2272.500 0.000 0,0 5220.162,3484.908 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_227_Conservation-Score_0"/>
<path d="M5194.414,3497.038 A2250.000,2250.000 40.000 0,1 5190.517,3513.940 L5234.328,3524.219 A2295.000,2295.000 0.000 0,0 5238.302,3506.979 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_228_Conservation-Score_1" class="Extracellular"/>
<path d="M5190.517,3513.940 A2250.000,2250.000 40.000 0,1 5186.490,3530.811 L5252.085,3546.735 A2317.500,2317.500 0.000 0,0 5256.233,3529.358 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_229_Conservation-Score_3"/>
<path d="M5186.490,3530.811 A2250.000,2250.000 40.000 0,1 5182.333,3547.650 L5247.803,3564.080 A2317.500,2317.500 0.000 0,0 5252.085,3546.735 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_230_Conservation-Score_2"/>
<path d="M5182.333,3547.650 A2250.000,2250.000 40.000 0,1 5178.047,3564.457 L5199.827,3570.102 A2272.500,2272.500 0.000 0,0 5204.157,3553.127 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_231_Conservation-Score_0" class="Extracellular"/>
<path d="M5178.047,3564.457 A2250.000,2250.000 40.000 0,1 5173.631,3581.230 L5217.104,3592.855 A2295.000,2295.000 0.000 0,0 5221.608,3575.746 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_232_Conservation-Score_1" class="Extracellular"/>
<path d="M5173.631,3581.230 A2250.000,2250.000 40.000 0,1 5169.086,3597.969 L5234.158,3615.908 A2317.500,2317.500 0.000 0,0 5238.840,3598.667 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_233_Conservation-Score_2"/>
<path d="M5169.086,3597.969 A2250.000,2250.000 40.000 0,1 5164.412,3614.672 L5250.988,3639.259 A2340.000,2340.000 0.000 0,0 5255.849,3621.888 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_234_Conservation-Score_4"/>
<path d="M5164.412,3614.672 A2250.000,2250.000 40.000 0,1 5159.609,3631.339 L5224.397,3650.279 A2317.500,2317.500 0.000 0,0 5229.344,3633.112 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_235_Conservation-Score_2" class="Extracellular"/>
<path d="M5159.609,3631.339 A2250.000,2250.000 40.000 0,1 5154.678,3647.968 L5219.318,3667.407 A2317.500,2317.500 0.000 0,0 5224.397,3650.279 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_236_Conservation-Score_2"/>
<path d="M5154.678,3647.968 A2250.000,2250.000 40.000 0,1 5149.619,3664.559 L5214.108,3684.495 A2317.500,2317.500 0.000 0,0 5219.318,3667.407 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_237_Conservation-Score_3" class="Extracellular"/>
<path d="M5149.619,3664.559 A2250.000,2250.000 40.000 0,1 5144.432,3681.110 L5187.321,3694.732 A2295.000,2295.000 0.000 0,0 5192.611,3677.850 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_238_Conservation-Score_1" class="Extracellular"/>
<path d="M5144.432,3681.110 A2250.000,2250.000 40.000 0,1 5139.118,3697.620 L5181.900,3711.573 A2295.000,2295.000 0.000 0,0 5187.321,3694.732 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_239_Conservation-Score_1"/>
<path d="M5139.118,3697.620 A2250.000,2250.000 40.000 0,1 5133.677,3714.090 L5197.687,3735.512 A2317.500,2317.500 0.000 0,0 5203.292,3718.549 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_240_Conservation-Score_2" class="Extracellular"/>
<path d="M5133.677,3714.090 A2250.000,2250.000 40.000 0,1 5128.108,3730.516 L5234.514,3767.042 A2362.500,2362.500 0.000 0,0 5240.360,3749.794 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_241_Conservation-Score_5" class="Extracellular"/>
<path d="M5128.108,3730.516 A2250.000,2250.000 40.000 0,1 5122.414,3746.900 L5186.086,3769.307 A2317.500,2317.500 0.000 0,0 5191.952,3752.432 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_242_Conservation-Score_3"/>
<path d="M5122.414,3746.900 A2250.000,2250.000 40.000 0,1 5116.593,3763.239 L5180.091,3786.136 A2317.500,2317.500 0.000 0,0 5186.086,3769.307 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_243_Conservation-Score_3"/>
<path d="M5116.593,3763.239 A2250.000,2250.000 40.000 0,1 5110.647,3779.532 L5173.966,3802.918 A2317.500,2317.500 0.000 0,0 5180.091,3786.136 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_244_Conservation-Score_3"/>
<path d="M5110.647,3779.532 A2250.000,2250.000 40.000 0,1 5104.575,3795.780 L5167.712,3819.653 A2317.500,2317.500 0.000 0,0 5173.966,3802.918 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_245_Conservation-Score_3" class="Extracellular"/>
<path d="M5104.575,3795.780 A2250.000,2250.000 40.000 0,1 5098.378,3811.980 L5119.361,3820.100 A2272.500,2272.500 0.000 0,0 5125.620,3803.738 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_246_Conservation-Score_0" class="Extracellular"/>
<path d="M5098.378,3811.980 A2250.000,2250.000 40.000 0,1 5092.056,3828.132 L5175.738,3861.257 A2340.000,2340.000 0.000 0,0 5182.313,3844.459 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_247_Conservation-Score_4" class="Extracellular"/>
<path d="M5092.056,3828.132 A2250.000,2250.000 40.000 0,1 5085.610,3844.234 L5148.178,3869.561 A2317.500,2317.500 0.000 0,0 5154.818,3852.976 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_248_Conservation-Score_2" class="Extracellular"/>
<path d="M5085.610,3844.234 A2250.000,2250.000 40.000 0,1 5079.040,3860.287 L5120.621,3877.492 A2295.000,2295.000 0.000 0,0 5127.322,3861.119 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_249_Conservation-Score_1"/>
<path d="M5079.040,3860.287 A2250.000,2250.000 40.000 0,1 5072.346,3876.288 L5113.793,3893.814 A2295.000,2295.000 0.000 0,0 5120.621,3877.492 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_250_Conservation-Score_1"/>
<path d="M5072.346,3876.288 A2250.000,2250.000 40.000 0,1 5065.530,3892.237 L5127.496,3919.004 A2317.500,2317.500 0.000 0,0 5134.517,3902.576 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_251_Conservation-Score_2"/>
<path d="M5065.530,3892.237 A2250.000,2250.000 40.000 0,1 5058.590,3908.133 L5120.348,3935.377 A2317.500,2317.500 0.000 0,0 5127.496,3919.004 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_252_Conservation-Score_3" class="Extracellular"/>
<path d="M5058.590,3908.133 A2250.000,2250.000 40.000 0,1 5051.529,3923.975 L5113.074,3951.695 A2317.500,2317.500 0.000 0,0 5120.348,3935.377 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_253_Conservation-Score_2" class="Extracellular"/>
<path d="M5051.529,3923.975 A2250.000,2250.000 40.000 0,1 5044.345,3939.763 L5105.675,3967.956 A2317.500,2317.500 0.000 0,0 5113.074,3951.695 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_254_Conservation-Score_3" class="Extracellular"/>
<path d="M5044.345,3939.763 A2250.000,2250.000 40.000 0,1 5037.040,3955.494 L5077.781,3974.604 A2295.000,2295.000 0.000 0,0 5085.232,3958.558 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_255_Conservation-Score_1" class="Extracellular"/>
<path d="M5037.040,3955.494 A2250.000,2250.000 40.000 0,1 5029.614,3971.169 L5090.502,4000.304 A2317.500,2317.500 0.000 0,0 5098.151,3984.159 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_256_Conservation-Score_2" class="Extracellular"/>
<path d="M5029.614,3971.169 A2250.000,2250.000 40.000 0,1 5022.067,3986.786 L5082.729,4016.389 A2317.500,2317.500 0.000 0,0 5090.502,4000.304 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_257_Conservation-Score_3" class="Extracellular"/>
<path d="M5022.067,3986.786 A2250.000,2250.000 40.000 0,1 5014.400,4002.344 L5034.544,4012.367 A2272.500,2272.500 0.000 0,0 5042.287,3996.654 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_258_Conservation-Score_0"/>
<path d="M5014.400,4002.344 A2250.000,2250.000 40.000 0,1 5006.613,4017.843 L5046.745,4038.200 A2295.000,2295.000 0.000 0,0 5054.688,4022.391 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_259_Conservation-Score_1" class="Extracellular"/>
<path d="M5006.613,4017.843 A2250.000,2250.000 40.000 0,1 4998.707,4033.281 L5058.668,4064.279 A2317.500,2317.500 0.000 0,0 5066.811,4048.378 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_260_Conservation-Score_3"/>
<path d="M4998.707,4033.281 A2250.000,2250.000 40.000 0,1 4990.682,4048.658 L5050.403,4080.118 A2317.500,2317.500 0.000 0,0 5058.668,4064.279 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_261_Conservation-Score_2"/>
<path d="M4990.682,4048.658 A2250.000,2250.000 40.000 0,1 4982.539,4063.972 L5042.016,4095.892 A2317.500,2317.500 0.000 0,0 5050.403,4080.118 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_262_Conservation-Score_2" class="Extracellular"/>
<path d="M4982.539,4063.972 A2250.000,2250.000 40.000 0,1 4974.279,4079.224 L5013.764,4100.808 A2295.000,2295.000 0.000 0,0 5022.190,4085.252 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_263_Conservation-Score_1"/>
<path d="M4974.279,4079.224 A2250.000,2250.000 40.000 0,1 4965.901,4094.411 L5024.878,4127.243 A2317.500,2317.500 0.000 0,0 5033.507,4111.600 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_264_Conservation-Score_2"/>
<path d="M4965.901,4094.411 A2250.000,2250.000 40.000 0,1 4957.406,4109.533 L4996.554,4131.724 A2295.000,2295.000 0.000 0,0 5005.219,4116.299 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_265_Conservation-Score_1"/>
<path d="M4957.406,4109.533 A2250.000,2250.000 40.000 0,1 4948.794,4124.589 L5007.258,4158.327 A2317.500,2317.500 0.000 0,0 5016.128,4142.819 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_266_Conservation-Score_2"/>
<path d="M4948.794,4124.589 A2250.000,2250.000 40.000 0,1 4940.067,4139.579 L4959.468,4150.974 A2272.500,2272.500 0.000 0,0 4968.282,4135.835 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_267_Conservation-Score_0" class="Extracellular"/>
<path d="M4940.067,4139.579 A2250.000,2250.000 40.000 0,1 4931.225,4154.500 L4989.162,4189.135 A2317.500,2317.500 0.000 0,0 4998.269,4173.766 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_268_Conservation-Score_3"/>
<path d="M4931.225,4154.500 A2250.000,2250.000 40.000 0,1 4922.268,4169.353 L4979.936,4204.434 A2317.500,2317.500 0.000 0,0 4989.162,4189.135 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_269_Conservation-Score_2" class="Extracellular"/>
<path d="M4922.268,4169.353 A2250.000,2250.000 40.000 0,1 4913.196,4184.137 L4932.328,4195.978 A2272.500,2272.500 0.000 0,0 4941.490,4181.047 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_270_Conservation-Score_0" class="Extracellular"/>
<path d="M4913.196,4184.137 A2250.000,2250.000 40.000 0,1 4904.011,4198.850 L4942.091,4222.827 A2295.000,2295.000 0.000 0,0 4951.460,4207.820 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_271_Conservation-Score_1" class="Extracellular"/>
<path d="M4904.011,4198.850 A2250.000,2250.000 40.000 0,1 4894.713,4213.492 L4951.554,4249.897 A2317.500,2317.500 0.000 0,0 4961.131,4234.816 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_272_Conservation-Score_3"/>
<path d="M4894.713,4213.492 A2250.000,2250.000 40.000 0,1 4885.302,4228.062 L4998.420,4301.746 A2385.000,2385.000 0.000 0,0 5008.396,4286.302 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_273_Conservation-Score_6"/>
<path d="M4885.302,4228.062 A2250.000,2250.000 40.000 0,1 4875.779,4242.559 L4988.326,4317.112 A2385.000,2385.000 0.000 0,0 4998.420,4301.746 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_274_Conservation-Score_6" class="Extracellular"/>
<path d="M4875.779,4242.559 A2250.000,2250.000 40.000 0,1 4866.145,4256.982 L4996.775,4344.970 A2407.500,2407.500 0.000 0,0 5007.084,4329.538 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_275_Conservation-Score_7" class="Extracellular"/>
<path d="M4866.145,4256.982 A2250.000,2250.000 40.000 0,1 4856.400,4271.330 L4967.784,4347.610 A2385.000,2385.000 0.000 0,0 4978.114,4332.401 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_276_Conservation-Score_6" class="Extracellular"/>
<path d="M4856.400,4271.330 A2250.000,2250.000 40.000 0,1 4846.544,4285.603 L4994.268,4388.451 A2430.000,2430.000 0.000 0,0 5004.912,4373.036 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_277_Conservation-Score_9"/>
<path d="M4846.544,4285.603 A2250.000,2250.000 40.000 0,1 4836.579,4299.799 L4928.408,4364.789 A2362.500,2362.500 0.000 0,0 4938.871,4349.883 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_278_Conservation-Score_5" class="Extracellular"/>
<path d="M4836.579,4299.799 A2250.000,2250.000 40.000 0,1 4826.504,4313.918 L5009.155,4445.310 A2475.000,2475.000 0.000 0,0 5020.237,4429.779 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_279_Conservation-Score_11" class="Extracellular"/>
<path d="M4826.504,4313.918 A2250.000,2250.000 40.000 0,1 4816.322,4327.959 L4943.464,4420.917 A2407.500,2407.500 0.000 0,0 4954.360,4405.893 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_280_Conservation-Score_7"/>
<path d="M4816.322,4327.959 A2250.000,2250.000 40.000 0,1 4806.031,4341.921 L4896.332,4409.018 A2362.500,2362.500 0.000 0,0 4907.138,4394.357 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_281_Conservation-Score_5"/>
<path d="M4806.031,4341.921 A2250.000,2250.000 40.000 0,1 4795.632,4355.804 L4885.414,4423.594 A2362.500,2362.500 0.000 0,0 4896.332,4409.018 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_282_Conservation-Score_5" class="Extracellular"/>
<path d="M4795.632,4355.804 A2250.000,2250.000 40.000 0,1 4785.128,4369.606 L4892.235,4451.782 A2385.000,2385.000 0.000 0,0 4903.370,4437.152 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_283_Conservation-Score_6"/>
<path d="M4785.128,4369.606 A2250.000,2250.000 40.000 0,1 4774.516,4383.326 L4951.968,4521.659 A2475.000,2475.000 0.000 0,0 4963.640,4506.566 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_284_Conservation-Score_11" class="Extracellular"/>
<path d="M4774.516,4383.326 A2250.000,2250.000 40.000 0,1 4763.800,4396.964 L4834.352,4452.843 A2340.000,2340.000 0.000 0,0 4845.497,4438.659 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_285_Conservation-Score_4" class="Extracellular"/>
<path d="M4763.800,4396.964 A2250.000,2250.000 40.000 0,1 4752.979,4410.520 L4805.568,4452.835 A2317.500,2317.500 0.000 0,0 4816.714,4438.873 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_286_Conservation-Score_2"/>
<path d="M4752.979,4410.520 A2250.000,2250.000 40.000 0,1 4742.053,4423.991 L4829.156,4495.190 A2362.500,2362.500 0.000 0,0 4840.628,4481.046 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_287_Conservation-Score_5"/>
<path d="M4742.053,4423.991 A2250.000,2250.000 40.000 0,1 4731.024,4437.378 L4765.645,4466.125 A2295.000,2295.000 0.000 0,0 4776.894,4452.471 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_288_Conservation-Score_1"/>
<path d="M4731.024,4437.378 A2250.000,2250.000 40.000 0,1 4719.893,4450.679 L4771.489,4494.199 A2317.500,2317.500 0.000 0,0 4782.955,4480.499 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_289_Conservation-Score_2"/>
<path d="M4719.893,4450.679 A2250.000,2250.000 40.000 0,1 4708.658,4463.894 L4742.832,4493.172 A2295.000,2295.000 0.000 0,0 4754.290,4479.693 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_290_Conservation-Score_1"/>
<path d="M4708.658,4463.894 A2250.000,2250.000 40.000 0,1 4697.323,4477.022 L4714.296,4491.793 A2272.500,2272.500 0.000 0,0 4725.745,4478.533 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_291_Conservation-Score_0" class="Extracellular"/>
<path d="M4697.323,4477.022 A2250.000,2250.000 40.000 0,1 4685.886,4490.063 L4753.322,4549.665 A2340.000,2340.000 0.000 0,0 4765.216,4536.103 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_292_Conservation-Score_4" class="Extracellular"/>
<path d="M4685.886,4490.063 A2250.000,2250.000 40.000 0,1 4674.350,4503.015 L4707.837,4533.075 A2295.000,2295.000 0.000 0,0 4719.604,4519.864 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_293_Conservation-Score_1"/>
<path d="M4674.350,4503.015 A2250.000,2250.000 40.000 0,1 4662.714,4515.877 L4712.595,4561.353 A2317.500,2317.500 0.000 0,0 4724.580,4548.105 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_294_Conservation-Score_2" class="Extracellular"/>
<path d="M4662.714,4515.877 A2250.000,2250.000 40.000 0,1 4650.979,4528.649 L4717.018,4589.795 A2340.000,2340.000 0.000 0,0 4729.222,4576.512 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_295_Conservation-Score_4" class="Extracellular"/>
<path d="M4650.979,4528.649 A2250.000,2250.000 40.000 0,1 4639.146,4541.331 L4704.712,4602.984 A2340.000,2340.000 0.000 0,0 4717.018,4589.795 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_296_Conservation-Score_4" class="Extracellular"/>
<path d="M4639.146,4541.331 A2250.000,2250.000 40.000 0,1 4627.215,4553.921 L4741.120,4662.696 A2407.500,2407.500 0.000 0,0 4753.886,4649.224 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_297_Conservation-Score_7" class="Extracellular"/>
<path d="M4627.215,4553.921 A2250.000,2250.000 40.000 0,1 4615.188,4566.419 L4663.644,4613.411 A2317.500,2317.500 0.000 0,0 4676.032,4600.539 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_298_Conservation-Score_3"/>
<path d="M4615.188,4566.419 A2250.000,2250.000 40.000 0,1 4603.065,4578.823 L4667.188,4641.976 A2340.000,2340.000 0.000 0,0 4679.796,4629.075 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_299_Conservation-Score_4" class="Extracellular"/>
<path d="M4603.065,4578.823 A2250.000,2250.000 40.000 0,1 4590.847,4591.134 L4718.114,4718.425 A2430.000,2430.000 0.000 0,0 4731.310,4705.129 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_300_Conservation-Score_8" class="Extracellular"/>
<path d="M4590.847,4591.134 A2250.000,2250.000 40.000 0,1 4578.534,4603.350 L4657.460,4683.518 A2362.500,2362.500 0.000 0,0 4670.389,4670.691 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_301_Conservation-Score_5"/>
<path d="M4578.534,4603.350 A2250.000,2250.000 40.000 0,1 4566.127,4615.471 L4628.772,4680.090 A2340.000,2340.000 0.000 0,0 4641.675,4667.484 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_302_Conservation-Score_4" class="Extracellular"/>
<path d="M4566.127,4615.471 A2250.000,2250.000 40.000 0,1 4553.627,4627.496 L4708.990,4790.246 A2475.000,2475.000 0.000 0,0 4722.740,4777.018 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_303_Conservation-Score_11" class="Extracellular"/>
<path d="M4553.627,4627.496 A2250.000,2250.000 40.000 0,1 4541.035,4639.424 L4618.087,4721.395 A2362.500,2362.500 0.000 0,0 4631.308,4708.871 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_304_Conservation-Score_5"/>
<path d="M4541.035,4639.424 A2250.000,2250.000 40.000 0,1 4528.351,4651.255 L4635.336,4766.843 A2407.500,2407.500 0.000 0,0 4648.907,4754.184 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_305_Conservation-Score_7" class="Extracellular"/>
<path d="M4528.351,4651.255 A2250.000,2250.000 40.000 0,1 4515.577,4662.988 L4561.044,4712.877 A2317.500,2317.500 0.000 0,0 4574.202,4700.793 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_306_Conservation-Score_3" class="Extracellular"/>
<path d="M4515.577,4662.988 A2250.000,2250.000 40.000 0,1 4502.712,4674.621 L4637.956,4825.337 A2452.500,2452.500 0.000 0,0 4651.979,4812.656 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_307_Conservation-Score_10"/>
<path d="M4502.712,4674.621 A2250.000,2250.000 40.000 0,1 4489.758,4686.156 L4519.553,4719.879 A2295.000,2295.000 0.000 0,0 4532.766,4708.114 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_308_Conservation-Score_1" class="Extracellular"/>
<path d="M4489.758,4686.156 A2250.000,2250.000 40.000 0,1 4476.716,4697.590 L4506.250,4731.542 A2295.000,2295.000 0.000 0,0 4519.553,4719.879 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_309_Conservation-Score_1"/>
<path d="M4476.716,4697.590 A2250.000,2250.000 40.000 0,1 4463.585,4708.923 L4507.493,4760.191 A2317.500,2317.500 0.000 0,0 4521.017,4748.517 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_310_Conservation-Score_3" class="Extracellular"/>
<path d="M4463.585,4708.923 A2250.000,2250.000 40.000 0,1 4450.368,4720.155 L4479.376,4754.558 A2295.000,2295.000 0.000 0,0 4492.857,4743.101 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_311_Conservation-Score_1" class="Extracellular"/>
<path d="M4450.368,4720.155 A2250.000,2250.000 40.000 0,1 4437.065,4731.284 L4465.806,4765.910 A2295.000,2295.000 0.000 0,0 4479.376,4754.558 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_312_Conservation-Score_1" class="Extracellular"/>
<path d="M4437.065,4731.284 A2250.000,2250.000 40.000 0,1 4423.676,4742.311 L4452.150,4777.157 A2295.000,2295.000 0.000 0,0 4465.806,4765.910 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_313_Conservation-Score_1" class="Extracellular"/>
<path d="M4423.676,4742.311 A2250.000,2250.000 40.000 0,1 4410.203,4753.234 L4424.305,4770.766 A2272.500,2272.500 0.000 0,0 4437.913,4759.734 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_314_Conservation-Score_0"/>
<path d="M4410.203,4753.234 A2250.000,2250.000 40.000 0,1 4396.646,4764.052 L4424.579,4799.333 A2295.000,2295.000 0.000 0,0 4438.407,4788.298 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_315_Conservation-Score_1"/>
<path d="M4396.646,4764.052 A2250.000,2250.000 40.000 0,1 4383.006,4774.766 L4424.496,4828.009 A2317.500,2317.500 0.000 0,0 4438.545,4816.974 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_316_Conservation-Score_3" class="Extracellular"/>
<path d="M4383.006,4774.766 A2250.000,2250.000 40.000 0,1 4369.283,4785.375 L4437.747,4874.644 A2362.500,2362.500 0.000 0,0 4452.156,4863.505 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_317_Conservation-Score_5" class="Extracellular"/>
<path d="M4369.283,4785.375 A2250.000,2250.000 40.000 0,1 4355.479,4795.877 L4423.253,4885.671 A2362.500,2362.500 0.000 0,0 4437.747,4874.644 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_318_Conservation-Score_5" class="Extracellular"/>
<path d="M4355.479,4795.877 A2250.000,2250.000 40.000 0,1 4341.595,4806.273 L4422.091,4914.649 A2385.000,2385.000 0.000 0,0 4436.808,4903.630 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_319_Conservation-Score_6" class="Extracellular"/>
<path d="M4341.595,4806.273 A2250.000,2250.000 40.000 0,1 4327.631,4816.561 L4367.460,4871.058 A2317.500,2317.500 0.000 0,0 4381.843,4860.461 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_320_Conservation-Score_2"/>
<path d="M4327.631,4816.561 A2250.000,2250.000 40.000 0,1 4313.588,4826.742 L4352.996,4881.544 A2317.500,2317.500 0.000 0,0 4367.460,4871.058 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_321_Conservation-Score_2" class="Extracellular"/>
<path d="M4313.588,4826.742 A2250.000,2250.000 40.000 0,1 4299.467,4836.814 L4312.462,4855.182 A2272.500,2272.500 0.000 0,0 4326.724,4845.009 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_322_Conservation-Score_0" class="Extracellular"/>
<path d="M4299.467,4836.814 A2250.000,2250.000 40.000 0,1 4285.269,4846.776 L4298.122,4865.244 A2272.500,2272.500 0.000 0,0 4312.462,4855.182 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_323_Conservation-Score_0"/>
<path d="M4285.269,4846.776 A2250.000,2250.000 40.000 0,1 4270.995,4856.629 L4296.415,4893.762 A2295.000,2295.000 0.000 0,0 4310.975,4883.712 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_324_Conservation-Score_1" class="Extracellular"/>
<path d="M4270.995,4856.629 A2250.000,2250.000 40.000 0,1 4256.645,4866.372 L4332.043,4978.354 A2385.000,2385.000 0.000 0,0 4347.254,4968.027 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_325_Conservation-Score_6"/>
<path d="M4256.645,4866.372 A2250.000,2250.000 40.000 0,1 4242.220,4876.004 L4291.909,4951.044 A2340.000,2340.000 0.000 0,0 4306.910,4941.027 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_326_Conservation-Score_4" class="Extracellular"/>
<path d="M4242.220,4876.004 A2250.000,2250.000 40.000 0,1 4227.721,4885.524 L4325.939,5036.366 A2430.000,2430.000 0.000 0,0 4341.597,5026.084 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_327_Conservation-Score_9" class="Extracellular"/>
<path d="M4227.721,4885.524 A2250.000,2250.000 40.000 0,1 4213.150,4894.932 L4298.070,5027.577 A2407.500,2407.500 0.000 0,0 4313.662,5017.511 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_328_Conservation-Score_7"/>
<path d="M4213.150,4894.932 A2250.000,2250.000 40.000 0,1 4198.506,4904.228 L4210.491,4923.270 A2272.500,2272.500 0.000 0,0 4225.281,4913.881 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_329_Conservation-Score_0"/>
<path d="M4198.506,4904.228 A2250.000,2250.000 40.000 0,1 4183.791,4913.410 L4207.467,4951.678 A2295.000,2295.000 0.000 0,0 4222.476,4942.312 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_330_Conservation-Score_1"/>
<path d="M4183.791,4913.410 A2250.000,2250.000 40.000 0,1 4169.006,4922.479 L4192.386,4960.928 A2295.000,2295.000 0.000 0,0 4207.467,4951.678 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_331_Conservation-Score_1"/>
<path d="M4169.006,4922.479 A2250.000,2250.000 40.000 0,1 4154.151,4931.433 L4165.693,4950.748 A2272.500,2272.500 0.000 0,0 4180.696,4941.704 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_332_Conservation-Score_0" class="Extracellular"/>
<path d="M4154.151,4931.433 A2250.000,2250.000 40.000 0,1 4139.228,4940.273 L4173.405,4998.481 A2317.500,2317.500 0.000 0,0 4188.776,4989.376 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_333_Conservation-Score_2"/>
<path d="M4139.228,4940.273 A2250.000,2250.000 40.000 0,1 4124.237,4948.997 L4157.964,5007.467 A2317.500,2317.500 0.000 0,0 4173.405,4998.481 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_334_Conservation-Score_3" class="Extracellular"/>
<path d="M4124.237,4948.997 A2250.000,2250.000 40.000 0,1 4109.179,4957.606 L4120.271,4977.182 A2272.500,2272.500 0.000 0,0 4135.479,4968.487 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_335_Conservation-Score_0"/>
<path d="M4109.179,4957.606 A2250.000,2250.000 40.000 0,1 4094.056,4966.098 L4126.877,5025.081 A2317.500,2317.500 0.000 0,0 4142.455,5016.334 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_336_Conservation-Score_2" class="Extracellular"/>
<path d="M4094.056,4966.098 A2250.000,2250.000 40.000 0,1 4078.867,4974.474 L4100.444,5013.963 A2295.000,2295.000 0.000 0,0 4115.937,5005.420 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_337_Conservation-Score_1" class="Extracellular"/>
<path d="M4078.867,4974.474 A2250.000,2250.000 40.000 0,1 4063.614,4982.732 L4084.886,5022.386 A2295.000,2295.000 0.000 0,0 4100.444,5013.963 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_338_Conservation-Score_1"/>
<path d="M4063.614,4982.732 A2250.000,2250.000 40.000 0,1 4048.298,4990.872 L4069.264,5030.689 A2295.000,2295.000 0.000 0,0 4084.886,5022.386 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_339_Conservation-Score_1" class="Extracellular"/>
<path d="M4048.298,4990.872 A2250.000,2250.000 40.000 0,1 4032.920,4998.894 L4053.578,5038.872 A2295.000,2295.000 0.000 0,0 4069.264,5030.689 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_340_Conservation-Score_1"/>
<path d="M4032.920,4998.894 A2250.000,2250.000 40.000 0,1 4017.480,5006.797 L4037.830,5046.933 A2295.000,2295.000 0.000 0,0 4053.578,5038.872 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_341_Conservation-Score_1" class="Extracellular"/>
<path d="M4017.480,5006.797 A2250.000,2250.000 40.000 0,1 4001.980,5014.581 L4052.079,5115.310 A2362.500,2362.500 0.000 0,0 4068.354,5107.137 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_342_Conservation-Score_5"/>
<path d="M4001.980,5014.581 A2250.000,2250.000 40.000 0,1 3986.420,5022.245 L4045.606,5143.580 A2385.000,2385.000 0.000 0,0 4062.099,5135.456 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_343_Conservation-Score_6"/>
<path d="M3986.420,5022.245 A2250.000,2250.000 40.000 0,1 3970.802,5029.789 L4029.050,5151.576 A2385.000,2385.000 0.000 0,0 4045.606,5143.580 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_344_Conservation-Score_6" class="Extracellular"/>
<path d="M3970.802,5029.789 A2250.000,2250.000 40.000 0,1 3955.126,5037.212 L3993.331,5118.701 A2340.000,2340.000 0.000 0,0 4009.634,5110.981 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_345_Conservation-Score_4"/>
<path d="M3955.126,5037.212 A2250.000,2250.000 40.000 0,1 3939.393,5044.515 L3976.969,5126.295 A2340.000,2340.000 0.000 0,0 3993.331,5118.701 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_346_Conservation-Score_4" class="Extracellular"/>
<path d="M3939.393,5044.515 A2250.000,2250.000 40.000 0,1 3923.605,5051.696 L3997.493,5215.831 A2430.000,2430.000 0.000 0,0 4014.545,5208.076 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_347_Conservation-Score_9" class="Extracellular"/>
<path d="M3923.605,5051.696 A2250.000,2250.000 40.000 0,1 3907.761,5058.754 L3971.304,5202.867 A2407.500,2407.500 0.000 0,0 3988.257,5195.314 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_348_Conservation-Score_7" class="Extracellular"/>
<path d="M3907.761,5058.754 A2250.000,2250.000 40.000 0,1 3891.864,5065.691 L3936.457,5168.975 A2362.500,2362.500 0.000 0,0 3953.149,5161.692 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_349_Conservation-Score_5" class="Extracellular"/>
<path d="M3891.864,5065.691 A2250.000,2250.000 40.000 0,1 3875.913,5072.505 L3928.468,5196.855 A2385.000,2385.000 0.000 0,0 3945.376,5189.632 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_350_Conservation-Score_6" class="Extracellular"/>
<path d="M3875.913,5072.505 A2250.000,2250.000 40.000 0,1 3859.911,5079.195 L3894.307,5162.363 A2340.000,2340.000 0.000 0,0 3910.950,5155.405 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_351_Conservation-Score_4" class="Extracellular"/>
<path d="M3859.911,5079.195 A2250.000,2250.000 40.000 0,1 3843.857,5085.762 L3886.050,5190.051 A2362.500,2362.500 0.000 0,0 3902.906,5183.155 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_352_Conservation-Score_5" class="Extracellular"/>
<path d="M3843.857,5085.762 A2250.000,2250.000 40.000 0,1 3827.754,5092.206 L3877.419,5217.738 A2385.000,2385.000 0.000 0,0 3894.489,5210.908 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_353_Conservation-Score_6"/>
<path d="M3827.754,5092.206 A2250.000,2250.000 40.000 0,1 3811.601,5098.524 L3884.645,5287.392 A2452.500,2452.500 0.000 0,0 3902.251,5280.504 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_354_Conservation-Score_10" class="Extracellular"/>
<path d="M3811.601,5098.524 A2250.000,2250.000 40.000 0,1 3795.400,5104.718 L3859.031,5273.096 A2430.000,2430.000 0.000 0,0 3876.529,5266.406 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_355_Conservation-Score_8" class="Extracellular"/>
<path d="M3795.400,5104.718 A2250.000,2250.000 40.000 0,1 3779.151,5110.787 L3825.900,5237.435 A2385.000,2385.000 0.000 0,0 3843.123,5231.002 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_356_Conservation-Score_6"/>
<path d="M3779.151,5110.787 A2250.000,2250.000 40.000 0,1 3762.856,5116.731 L3793.371,5201.400 A2340.000,2340.000 0.000 0,0 3810.317,5195.219 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_357_Conservation-Score_4"/>
<path d="M3762.856,5116.731 A2250.000,2250.000 40.000 0,1 3746.516,5122.549 L3806.238,5292.353 A2430.000,2430.000 0.000 0,0 3823.885,5286.069 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_358_Conservation-Score_8" class="Extracellular"/>
<path d="M3746.516,5122.549 A2250.000,2250.000 40.000 0,1 3730.132,5128.240 L3744.735,5170.805 A2295.000,2295.000 0.000 0,0 3761.447,5165.000 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_359_Conservation-Score_1"/>
<path d="M3730.132,5128.240 A2250.000,2250.000 40.000 0,1 3713.704,5133.806 L3727.978,5176.482 A2295.000,2295.000 0.000 0,0 3744.735,5170.805 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_360_Conservation-Score_1"/>
<path d="M3713.704,5133.806 A2250.000,2250.000 40.000 0,1 3697.234,5139.244 L3718.151,5203.421 A2317.500,2317.500 0.000 0,0 3735.115,5197.820 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_361_Conservation-Score_2" class="Extracellular"/>
<path d="M3697.234,5139.244 A2250.000,2250.000 40.000 0,1 3680.722,5144.555 L3701.144,5208.892 A2317.500,2317.500 0.000 0,0 3718.151,5203.421 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_362_Conservation-Score_3"/>
<path d="M3680.722,5144.555 A2250.000,2250.000 40.000 0,1 3664.170,5149.739 L3690.737,5235.729 A2340.000,2340.000 0.000 0,0 3707.951,5230.337 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_363_Conservation-Score_4" class="Extracellular"/>
<path d="M3664.170,5149.739 A2250.000,2250.000 40.000 0,1 3647.579,5154.795 L3667.006,5219.439 A2317.500,2317.500 0.000 0,0 3684.095,5214.231 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_364_Conservation-Score_3"/>
<path d="M3647.579,5154.795 A2250.000,2250.000 40.000 0,1 3630.949,5159.723 L3649.877,5224.515 A2317.500,2317.500 0.000 0,0 3667.006,5219.439 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_365_Conservation-Score_3" class="Extracellular"/>
<path d="M3630.949,5159.723 A2250.000,2250.000 40.000 0,1 3614.281,5164.523 L3626.567,5207.813 A2295.000,2295.000 0.000 0,0 3643.568,5202.918 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_366_Conservation-Score_1" class="Extracellular"/>
<path d="M3614.281,5164.523 A2250.000,2250.000 40.000 0,1 3597.577,5169.194 L3633.432,5299.345 A2385.000,2385.000 0.000 0,0 3651.138,5294.394 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_367_Conservation-Score_6"/>
<path d="M3597.577,5169.194 A2250.000,2250.000 40.000 0,1 3580.837,5173.736 L3604.071,5260.685 A2340.000,2340.000 0.000 0,0 3621.480,5255.962 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_368_Conservation-Score_4" class="Extracellular"/>
<path d="M3580.837,5173.736 A2250.000,2250.000 40.000 0,1 3564.063,5178.149 L3620.470,5395.964 A2475.000,2475.000 0.000 0,0 3638.921,5391.110 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_369_Conservation-Score_11" class="Extracellular"/>
<path d="M3564.063,5178.149 A2250.000,2250.000 40.000 0,1 3547.256,5182.432 L3574.619,5291.554 A2362.500,2362.500 0.000 0,0 3592.267,5287.056 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_370_Conservation-Score_5"/>
<path d="M3547.256,5182.432 A2250.000,2250.000 40.000 0,1 3530.416,5186.586 L3541.024,5230.318 A2295.000,2295.000 0.000 0,0 3558.201,5226.081 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_371_Conservation-Score_1"/>
<path d="M3530.416,5186.586 A2250.000,2250.000 40.000 0,1 3513.544,5190.610 L3528.950,5256.328 A2317.500,2317.500 0.000 0,0 3546.328,5252.184 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_372_Conservation-Score_3"/>
<path d="M3513.544,5190.610 A2250.000,2250.000 40.000 0,1 3496.642,5194.504 L3511.541,5260.339 A2317.500,2317.500 0.000 0,0 3528.950,5256.328 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_373_Conservation-Score_3" class="Extracellular"/>
<path d="M3496.642,5194.504 A2250.000,2250.000 40.000 0,1 3479.710,5198.267 L3498.899,5286.198 A2340.000,2340.000 0.000 0,0 3516.508,5282.284 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_374_Conservation-Score_4" class="Extracellular"/>
<path d="M3479.710,5198.267 A2250.000,2250.000 40.000 0,1 3462.750,5201.900 L3485.888,5311.995 A2362.500,2362.500 0.000 0,0 3503.696,5308.180 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_375_Conservation-Score_5" class="Extracellular"/>
<path d="M3462.750,5201.900 A2250.000,2250.000 40.000 0,1 3445.762,5205.402 L3450.220,5227.456 A2272.500,2272.500 0.000 0,0 3467.378,5223.919 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_376_Conservation-Score_0" class="Extracellular"/>
<path d="M3445.762,5205.402 A2250.000,2250.000 40.000 0,1 3428.748,5208.772 L3458.761,5363.386 A2407.500,2407.500 0.000 0,0 3476.966,5359.780 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_377_Conservation-Score_7" class="Extracellular"/>
<path d="M3428.748,5208.772 A2250.000,2250.000 40.000 0,1 3411.709,5212.012 L3428.177,5300.492 A2340.000,2340.000 0.000 0,0 3445.898,5297.123 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_378_Conservation-Score_4"/>
<path d="M3411.709,5212.012 A2250.000,2250.000 40.000 0,1 3394.645,5215.120 L3418.323,5348.027 A2385.000,2385.000 0.000 0,0 3436.411,5344.732 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_379_Conservation-Score_6"/>
<path d="M3394.645,5215.120 A2250.000,2250.000 40.000 0,1 3377.557,5218.096 L3400.210,5351.182 A2385.000,2385.000 0.000 0,0 3418.323,5348.027 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_380_Conservation-Score_6" class="Extracellular"/>
<path d="M3377.557,5218.096 A2250.000,2250.000 40.000 0,1 3360.447,5220.941 L3385.678,5376.407 A2407.500,2407.500 0.000 0,0 3403.986,5373.363 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_381_Conservation-Score_7"/>
<path d="M3360.447,5220.941 A2250.000,2250.000 40.000 0,1 3343.316,5223.653 L3370.781,5401.546 A2430.000,2430.000 0.000 0,0 3389.283,5398.616 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_382_Conservation-Score_8"/>
<path d="M3343.316,5223.653 A2250.000,2250.000 40.000 0,1 3326.164,5226.234 L3345.734,5359.808 A2385.000,2385.000 0.000 0,0 3363.914,5357.073 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_383_Conservation-Score_6"/>
<path d="M3326.164,5226.234 A2250.000,2250.000 40.000 0,1 3308.993,5228.682 L3315.172,5273.256 A2295.000,2295.000 0.000 0,0 3332.687,5270.759 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_384_Conservation-Score_1" class="Extracellular"/>
<path d="M3308.993,5228.682 A2250.000,2250.000 40.000 0,1 3291.803,5230.998 L3297.639,5275.618 A2295.000,2295.000 0.000 0,0 3315.172,5273.256 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_385_Conservation-Score_1"/>
<path d="M3291.803,5230.998 A2250.000,2250.000 40.000 0,1 3274.596,5233.181 L3280.088,5277.845 A2295.000,2295.000 0.000 0,0 3297.639,5275.618 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_386_Conservation-Score_1"/>
<path d="M3274.596,5233.181 A2250.000,2250.000 40.000 0,1 3257.373,5235.231 L3259.947,5257.584 A2272.500,2272.500 0.000 0,0 3277.342,5255.513 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_387_Conservation-Score_0" class="Extracellular"/>
<path d="M3257.373,5235.231 A2250.000,2250.000 40.000 0,1 3240.134,5237.149 L3244.937,5281.892 A2295.000,2295.000 0.000 0,0 3262.520,5279.936 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_388_Conservation-Score_1"/>
<path d="M3240.134,5237.149 A2250.000,2250.000 40.000 0,1 3222.882,5238.934 L3229.568,5306.102 A2317.500,2317.500 0.000 0,0 3247.338,5304.263 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_389_Conservation-Score_2"/>
<path d="M3222.882,5238.934 A2250.000,2250.000 40.000 0,1 3205.616,5240.585 L3211.784,5307.803 A2317.500,2317.500 0.000 0,0 3229.568,5306.102 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_390_Conservation-Score_2"/>
<path d="M3205.616,5240.585 A2250.000,2250.000 40.000 0,1 3188.337,5242.104 L3193.987,5309.367 A2317.500,2317.500 0.000 0,0 3211.784,5307.803 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_391_Conservation-Score_2" class="Extracellular"/>
<path d="M3188.337,5242.104 A2250.000,2250.000 40.000 0,1 3171.048,5243.489 L3176.179,5310.794 A2317.500,2317.500 0.000 0,0 3193.987,5309.367 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_392_Conservation-Score_2" class="Extracellular"/>
<path d="M3171.048,5243.489 A2250.000,2250.000 40.000 0,1 3153.748,5244.741 L3155.286,5267.188 A2272.500,2272.500 0.000 0,0 3172.758,5265.924 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_393_Conservation-Score_0" class="Extracellular"/>
<path d="M3153.748,5244.741 A2250.000,2250.000 40.000 0,1 3136.439,5245.859 L3140.533,5313.235 A2317.500,2317.500 0.000 0,0 3158.361,5312.083 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_394_Conservation-Score_2"/>
<path d="M3136.439,5245.859 A2250.000,2250.000 40.000 0,1 3119.123,5246.844 L3121.505,5291.781 A2295.000,2295.000 0.000 0,0 3139.168,5290.777 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_395_Conservation-Score_1" class="Extracellular"/>
<path d="M3119.123,5246.844 A2250.000,2250.000 40.000 0,1 3101.799,5247.696 L3105.871,5337.604 A2340.000,2340.000 0.000 0,0 3123.888,5336.718 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_396_Conservation-Score_4" class="Extracellular"/>
<path d="M3101.799,5247.696 A2250.000,2250.000 40.000 0,1 3084.469,5248.414 L3090.382,5405.803 A2407.500,2407.500 0.000 0,0 3108.925,5405.035 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_397_Conservation-Score_7"/>
<path d="M3084.469,5248.414 A2250.000,2250.000 40.000 0,1 3067.134,5248.998 L3072.504,5428.918 A2430.000,2430.000 0.000 0,0 3091.226,5428.287 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_398_Conservation-Score_8" class="Extracellular"/>
<path d="M3067.134,5248.998 A2250.000,2250.000 40.000 0,1 3049.795,5249.449 L3051.787,5339.427 A2340.000,2340.000 0.000 0,0 3069.819,5338.958 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_399_Conservation-Score_4" class="Extracellular"/>
<path d="M3049.795,5249.449 A2250.000,2250.000 40.000 0,1 3032.453,5249.766 L3033.426,5317.259 A2317.500,2317.500 0.000 0,0 3051.289,5316.932 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_400_Conservation-Score_3"/>
<path d="M3032.453,5249.766 A2250.000,2250.000 40.000 0,1 3015.109,5249.949 L3015.713,5339.947 A2340.000,2340.000 0.000 0,0 3033.751,5339.757 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_401_Conservation-Score_4" class="Extracellular"/>
<path d="M3015.109,5249.949 A2250.000,2250.000 40.000 0,1 2997.764,5249.999 L2997.697,5317.499 A2317.500,2317.500 0.000 0,0 3015.562,5317.448 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_402_Conservation-Score_3" class="Extracellular"/>
<path d="M2997.764,5249.999 A2250.000,2250.000 40.000 0,1 2980.419,5249.915 L2978.853,5429.908 A2430.000,2430.000 0.000 0,0 2997.585,5429.999 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_403_Conservation-Score_8"/>
<path d="M2980.419,5249.915 A2250.000,2250.000 40.000 0,1 2963.076,5249.697 L2960.861,5384.679 A2385.000,2385.000 0.000 0,0 2979.245,5384.910 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_404_Conservation-Score_6" class="Extracellular"/>
<path d="M2963.076,5249.697 A2250.000,2250.000 40.000 0,1 2945.735,5249.346 L2940.308,5474.280 A2475.000,2475.000 0.000 0,0 2959.384,5474.667 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_405_Conservation-Score_11" class="Extracellular"/>
<path d="M2945.735,5249.346 A2250.000,2250.000 40.000 0,1 2928.397,5248.860 L2924.817,5361.303 A2362.500,2362.500 0.000 0,0 2943.021,5361.813 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_406_Conservation-Score_5"/>
<path d="M2928.397,5248.860 A2250.000,2250.000 40.000 0,1 2911.063,5248.242 L2903.948,5428.101 A2430.000,2430.000 0.000 0,0 2922.668,5428.769 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_407_Conservation-Score_8"/>
<path d="M2911.063,5248.242 A2250.000,2250.000 40.000 0,1 2893.734,5247.489 L2886.296,5404.813 A2407.500,2407.500 0.000 0,0 2904.837,5405.618 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_408_Conservation-Score_7"/>
<path d="M2893.734,5247.489 A2250.000,2250.000 40.000 0,1 2876.412,5246.603 L2867.761,5403.865 A2407.500,2407.500 0.000 0,0 2886.296,5404.813 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_409_Conservation-Score_7" class="Extracellular"/>
<path d="M2876.412,5246.603 A2250.000,2250.000 40.000 0,1 2859.097,5245.584 L2854.870,5312.951 A2317.500,2317.500 0.000 0,0 2872.705,5314.001 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_410_Conservation-Score_3"/>
<path d="M2859.097,5245.584 A2250.000,2250.000 40.000 0,1 2841.791,5244.431 L2830.716,5401.541 A2407.500,2407.500 0.000 0,0 2849.234,5402.775 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_411_Conservation-Score_7" class="Extracellular"/>
<path d="M2841.791,5244.431 A2250.000,2250.000 40.000 0,1 2824.494,5243.145 L2813.963,5377.733 A2385.000,2385.000 0.000 0,0 2832.298,5379.097 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_412_Conservation-Score_6"/>
<path d="M2824.494,5243.145 A2250.000,2250.000 40.000 0,1 2807.207,5241.725 L2793.712,5398.646 A2407.500,2407.500 0.000 0,0 2812.208,5400.165 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_413_Conservation-Score_7" class="Extracellular"/>
<path d="M2807.207,5241.725 A2250.000,2250.000 40.000 0,1 2789.932,5240.172 L2773.126,5419.386 A2430.000,2430.000 0.000 0,0 2791.784,5421.063 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_414_Conservation-Score_8"/>
<path d="M2789.932,5240.172 A2250.000,2250.000 40.000 0,1 2772.669,5238.486 L2749.936,5462.335 A2475.000,2475.000 0.000 0,0 2768.925,5464.189 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_415_Conservation-Score_11"/>
<path d="M2772.669,5238.486 A2250.000,2250.000 40.000 0,1 2755.420,5236.667 L2748.083,5303.767 A2317.500,2317.500 0.000 0,0 2765.849,5305.641 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_416_Conservation-Score_3" class="Extracellular"/>
<path d="M2755.420,5236.667 A2250.000,2250.000 40.000 0,1 2738.185,5234.715 L2717.240,5413.493 A2430.000,2430.000 0.000 0,0 2735.854,5415.601 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_417_Conservation-Score_8"/>
<path d="M2738.185,5234.715 A2250.000,2250.000 40.000 0,1 2720.966,5232.631 L2707.014,5344.262 A2362.500,2362.500 0.000 0,0 2725.095,5346.451 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_418_Conservation-Score_5"/>
<path d="M2720.966,5232.631 A2250.000,2250.000 40.000 0,1 2703.764,5230.413 L2685.989,5364.238 A2385.000,2385.000 0.000 0,0 2704.224,5366.589 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_419_Conservation-Score_6" class="Extracellular"/>
<path d="M2703.764,5230.413 A2250.000,2250.000 40.000 0,1 2686.579,5228.064 L2677.176,5294.905 A2317.500,2317.500 0.000 0,0 2694.877,5297.326 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_420_Conservation-Score_3" class="Extracellular"/>
<path d="M2686.579,5228.064 A2250.000,2250.000 40.000 0,1 2669.412,5225.581 L2652.883,5336.860 A2362.500,2362.500 0.000 0,0 2670.908,5339.467 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_421_Conservation-Score_5" class="Extracellular"/>
<path d="M2669.412,5225.581 A2250.000,2250.000 40.000 0,1 2652.266,5222.967 L2631.402,5356.345 A2385.000,2385.000 0.000 0,0 2649.577,5359.116 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_422_Conservation-Score_6"/>
<path d="M2652.266,5222.967 A2250.000,2250.000 40.000 0,1 2635.140,5220.220 L2605.951,5397.838 A2430.000,2430.000 0.000 0,0 2624.447,5400.804 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_423_Conservation-Score_8"/>
<path d="M2635.140,5220.220 A2250.000,2250.000 40.000 0,1 2618.035,5217.341 L2579.839,5439.076 A2475.000,2475.000 0.000 0,0 2598.654,5442.242 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_424_Conservation-Score_11" class="Extracellular"/>
<path d="M2618.035,5217.341 A2250.000,2250.000 40.000 0,1 2600.954,5214.331 L2581.002,5325.048 A2362.500,2362.500 0.000 0,0 2598.937,5328.209 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_425_Conservation-Score_5" class="Extracellular"/>
<path d="M2600.954,5214.331 A2250.000,2250.000 40.000 0,1 2583.896,5211.189 L2571.413,5277.525 A2317.500,2317.500 0.000 0,0 2588.982,5280.761 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_426_Conservation-Score_2" class="Extracellular"/>
<path d="M2583.896,5211.189 A2250.000,2250.000 40.000 0,1 2566.863,5207.916 L2553.869,5274.153 A2317.500,2317.500 0.000 0,0 2571.413,5277.525 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_427_Conservation-Score_3"/>
<path d="M2566.863,5207.916 A2250.000,2250.000 40.000 0,1 2549.855,5204.511 L2522.847,5336.782 A2385.000,2385.000 0.000 0,0 2540.875,5340.391 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_428_Conservation-Score_6" class="Extracellular"/>
<path d="M2549.855,5204.511 A2250.000,2250.000 40.000 0,1 2532.875,5200.976 L2528.203,5222.985 A2272.500,2272.500 0.000 0,0 2545.354,5226.556 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_429_Conservation-Score_0" class="Extracellular"/>
<path d="M2532.875,5200.976 A2250.000,2250.000 40.000 0,1 2515.922,5197.309 L2501.399,5263.229 A2317.500,2317.500 0.000 0,0 2518.861,5267.005 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_430_Conservation-Score_3"/>
<path d="M2515.922,5197.309 A2250.000,2250.000 40.000 0,1 2498.998,5193.512 L2463.927,5347.058 A2407.500,2407.500 0.000 0,0 2482.036,5351.121 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_431_Conservation-Score_7" class="Extracellular"/>
<path d="M2498.998,5193.512 A2250.000,2250.000 40.000 0,1 2482.103,5189.585 L2440.672,5364.752 A2430.000,2430.000 0.000 0,0 2458.917,5368.993 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_432_Conservation-Score_8" class="Extracellular"/>
<path d="M2482.103,5189.585 A2250.000,2250.000 40.000 0,1 2465.240,5185.528 L2427.806,5338.515 A2407.500,2407.500 0.000 0,0 2445.850,5342.856 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_433_Conservation-Score_7"/>
<path d="M2465.240,5185.528 A2250.000,2250.000 40.000 0,1 2448.408,5181.340 L2404.280,5355.848 A2430.000,2430.000 0.000 0,0 2422.459,5360.370 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_434_Conservation-Score_9"/>
<path d="M2448.408,5181.340 A2250.000,2250.000 40.000 0,1 2431.609,5177.024 L2403.189,5285.875 A2362.500,2362.500 0.000 0,0 2420.828,5290.407 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_435_Conservation-Score_5"/>
<path d="M2431.609,5177.024 A2250.000,2250.000 40.000 0,1 2414.844,5172.577 L2362.179,5368.109 A2452.500,2452.500 0.000 0,0 2380.454,5372.956 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_436_Conservation-Score_10"/>
<path d="M2414.844,5172.577 A2250.000,2250.000 40.000 0,1 2398.113,5168.002 L2355.981,5319.762 A2407.500,2407.500 0.000 0,0 2373.883,5324.658 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_437_Conservation-Score_7"/>
<path d="M2398.113,5168.002 A2250.000,2250.000 40.000 0,1 2381.418,5163.298 L2350.489,5271.463 A2362.500,2362.500 0.000 0,0 2368.019,5276.402 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_438_Conservation-Score_5"/>
<path d="M2381.418,5163.298 A2250.000,2250.000 40.000 0,1 2364.760,5158.465 L2326.646,5287.973 A2385.000,2385.000 0.000 0,0 2344.303,5293.095 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_439_Conservation-Score_6"/>
<path d="M2364.760,5158.465 A2250.000,2250.000 40.000 0,1 2348.140,5153.504 L2282.954,5368.854 A2475.000,2475.000 0.000 0,0 2301.236,5374.311 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_440_Conservation-Score_11"/>
<path d="M2348.140,5153.504 A2250.000,2250.000 40.000 0,1 2331.559,5148.415 L2304.821,5234.351 A2340.000,2340.000 0.000 0,0 2322.066,5239.644 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_441_Conservation-Score_4"/>
<path d="M2331.559,5148.415 A2250.000,2250.000 40.000 0,1 2315.017,5143.198 L2267.068,5293.222 A2407.500,2407.500 0.000 0,0 2284.768,5298.804 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_442_Conservation-Score_7" class="Extracellular"/>
<path d="M2315.017,5143.198 A2250.000,2250.000 40.000 0,1 2298.516,5137.854 L2249.412,5287.504 A2407.500,2407.500 0.000 0,0 2267.068,5293.222 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_443_Conservation-Score_7"/>
<path d="M2298.516,5137.854 A2250.000,2250.000 40.000 0,1 2282.056,5132.383 L2238.980,5260.326 A2385.000,2385.000 0.000 0,0 2256.427,5266.125 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_444_Conservation-Score_6" class="Extracellular"/>
<path d="M2282.056,5132.383 A2250.000,2250.000 40.000 0,1 2265.640,5126.785 L2206.891,5296.928 A2430.000,2430.000 0.000 0,0 2224.621,5302.974 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_445_Conservation-Score_8" class="Extracellular"/>
<path d="M2265.640,5126.785 A2250.000,2250.000 40.000 0,1 2249.267,5121.061 L2211.730,5227.114 A2362.500,2362.500 0.000 0,0 2228.922,5233.124 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_446_Conservation-Score_5"/>
<path d="M2249.267,5121.061 A2250.000,2250.000 40.000 0,1 2232.938,5115.211 L2194.585,5220.971 A2362.500,2362.500 0.000 0,0 2211.730,5227.114 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_447_Conservation-Score_5"/>
<path d="M2232.938,5115.211 A2250.000,2250.000 40.000 0,1 2216.655,5109.235 L2161.821,5256.881 A2407.500,2407.500 0.000 0,0 2179.244,5263.275 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_448_Conservation-Score_7" class="Extracellular"/>
<path d="M2216.655,5109.235 A2250.000,2250.000 40.000 0,1 2200.419,5103.133 L2136.453,5271.384 A2430.000,2430.000 0.000 0,0 2153.988,5277.974 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_449_Conservation-Score_8" class="Extracellular"/>
<path d="M2200.419,5103.133 A2250.000,2250.000 40.000 0,1 2184.230,5096.907 L2110.811,5285.629 A2452.500,2452.500 0.000 0,0 2128.457,5292.415 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_450_Conservation-Score_10"/>
<path d="M2184.230,5096.907 A2250.000,2250.000 40.000 0,1 2168.090,5090.556 L2084.899,5299.612 A2475.000,2475.000 0.000 0,0 2102.653,5306.598 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_451_Conservation-Score_11" class="Extracellular"/>
<path d="M2168.090,5090.556 A2250.000,2250.000 40.000 0,1 2151.999,5084.081 L2092.639,5229.967 A2407.500,2407.500 0.000 0,0 2109.856,5236.895 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_452_Conservation-Score_7" class="Extracellular"/>
<path d="M2151.999,5084.081 A2250.000,2250.000 40.000 0,1 2135.959,5077.482 L2049.554,5285.230 A2475.000,2475.000 0.000 0,0 2067.199,5292.489 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_453_Conservation-Score_11"/>
<path d="M2135.959,5077.482 A2250.000,2250.000 40.000 0,1 2119.969,5070.760 L2075.968,5174.298 A2362.500,2362.500 0.000 0,0 2092.757,5181.356 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_454_Conservation-Score_5" class="Extracellular"/>
<path d="M2119.969,5070.760 A2250.000,2250.000 40.000 0,1 2104.033,5063.914 L2059.234,5167.110 A2362.500,2362.500 0.000 0,0 2075.968,5174.298 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_455_Conservation-Score_5" class="Extracellular"/>
<path d="M2104.033,5063.914 A2250.000,2250.000 40.000 0,1 2088.149,5056.946 L2024.319,5200.932 A2407.500,2407.500 0.000 0,0 2041.315,5208.388 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_456_Conservation-Score_7" class="Extracellular"/>
<path d="M2088.149,5056.946 A2250.000,2250.000 40.000 0,1 2072.320,5049.856 L2044.489,5111.352 A2317.500,2317.500 0.000 0,0 2060.793,5118.655 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_457_Conservation-Score_3"/>
<path d="M2072.320,5049.856 A2250.000,2250.000 40.000 0,1 2056.545,5042.644 L2018.807,5124.349 A2340.000,2340.000 0.000 0,0 2035.212,5131.850 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_458_Conservation-Score_4"/>
<path d="M2056.545,5042.644 A2250.000,2250.000 40.000 0,1 2040.827,5035.310 L2002.460,5116.723 A2340.000,2340.000 0.000 0,0 2018.807,5124.349 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_459_Conservation-Score_4" class="Extracellular"/>
<path d="M2040.827,5035.310 A2250.000,2250.000 40.000 0,1 2025.166,5027.856 L1995.921,5088.691 A2317.500,2317.500 0.000 0,0 2012.052,5096.369 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_460_Conservation-Score_3" class="Extracellular"/>
<path d="M2025.166,5027.856 A2250.000,2250.000 40.000 0,1 2009.563,5020.281 L1950.136,5141.497 A2385.000,2385.000 0.000 0,0 1966.676,5149.527 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_461_Conservation-Score_6" class="Extracellular"/>
<path d="M2009.563,5020.281 A2250.000,2250.000 40.000 0,1 1994.018,5012.586 L1933.659,5133.341 A2385.000,2385.000 0.000 0,0 1950.136,5141.497 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_462_Conservation-Score_6" class="Extracellular"/>
<path d="M1994.018,5012.586 A2250.000,2250.000 40.000 0,1 1978.533,5004.771 L1947.889,5064.914 A2317.500,2317.500 0.000 0,0 1963.839,5072.963 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_463_Conservation-Score_3"/>
<path d="M1978.533,5004.771 A2250.000,2250.000 40.000 0,1 1963.110,4996.837 L1911.265,5096.679 A2362.500,2362.500 0.000 0,0 1927.460,5105.009 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_464_Conservation-Score_5"/>
<path d="M1963.110,4996.837 A2250.000,2250.000 40.000 0,1 1947.747,4988.785 L1884.612,5108.112 A2385.000,2385.000 0.000 0,0 1900.896,5116.647 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_465_Conservation-Score_6"/>
<path d="M1947.747,4988.785 A2250.000,2250.000 40.000 0,1 1932.447,4980.614 L1889.745,5059.838 A2340.000,2340.000 0.000 0,0 1905.657,5068.336 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_466_Conservation-Score_4"/>
<path d="M1932.447,4980.614 A2250.000,2250.000 40.000 0,1 1917.211,4972.326 L1884.727,5031.495 A2317.500,2317.500 0.000 0,0 1900.421,5040.032 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_467_Conservation-Score_2" class="Extracellular"/>
<path d="M1917.211,4972.326 A2250.000,2250.000 40.000 0,1 1902.039,4963.920 L1803.223,5140.673 A2452.500,2452.500 0.000 0,0 1819.760,5149.835 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_468_Conservation-Score_10" class="Extracellular"/>
<path d="M1902.039,4963.920 A2250.000,2250.000 40.000 0,1 1886.932,4955.398 L1853.540,5014.060 A2317.500,2317.500 0.000 0,0 1869.100,5022.838 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_469_Conservation-Score_3" class="Extracellular"/>
<path d="M1886.932,4955.398 A2250.000,2250.000 40.000 0,1 1871.892,4946.759 L1804.205,5063.565 A2385.000,2385.000 0.000 0,0 1820.148,5072.722 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_470_Conservation-Score_6"/>
<path d="M1871.892,4946.759 A2250.000,2250.000 40.000 0,1 1856.918,4938.005 L1834.056,4976.765 A2295.000,2295.000 0.000 0,0 1849.329,4985.694 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_471_Conservation-Score_1"/>
<path d="M1856.918,4938.005 A2250.000,2250.000 40.000 0,1 1842.012,4929.136 L1760.953,5064.175 A2407.500,2407.500 0.000 0,0 1776.902,5073.665 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_472_Conservation-Score_7"/>
<path d="M1842.012,4929.136 A2250.000,2250.000 40.000 0,1 1827.176,4920.152 L1745.078,5054.562 A2407.500,2407.500 0.000 0,0 1760.953,5064.175 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_473_Conservation-Score_7" class="Extracellular"/>
<path d="M1827.176,4920.152 A2250.000,2250.000 40.000 0,1 1812.408,4911.054 L1764.905,4987.496 A2340.000,2340.000 0.000 0,0 1780.263,4996.958 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_474_Conservation-Score_4"/>
<path d="M1812.408,4911.054 A2250.000,2250.000 40.000 0,1 1797.712,4901.842 L1773.666,4939.879 A2295.000,2295.000 0.000 0,0 1788.657,4949.275 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_475_Conservation-Score_1" class="Extracellular"/>
<path d="M1797.712,4901.842 A2250.000,2250.000 40.000 0,1 1783.087,4892.517 L1697.903,5024.994 A2407.500,2407.500 0.000 0,0 1713.552,5034.971 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_476_Conservation-Score_7"/>
<path d="M1783.087,4892.517 A2250.000,2250.000 40.000 0,1 1768.534,4883.080 L1694.646,4996.065 A2385.000,2385.000 0.000 0,0 1710.072,5006.068 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_477_Conservation-Score_6"/>
<path d="M1768.534,4883.080 A2250.000,2250.000 40.000 0,1 1754.054,4873.531 L1679.297,4985.943 A2385.000,2385.000 0.000 0,0 1694.646,4996.065 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_478_Conservation-Score_6" class="Extracellular"/>
<path d="M1754.054,4873.531 A2250.000,2250.000 40.000 0,1 1739.649,4863.871 L1676.631,4957.064 A2362.500,2362.500 0.000 0,0 1691.757,4967.208 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_479_Conservation-Score_5" class="Extracellular"/>
<path d="M1739.649,4863.871 A2250.000,2250.000 40.000 0,1 1725.318,4854.100 L1648.837,4965.346 A2385.000,2385.000 0.000 0,0 1664.028,4975.703 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_480_Conservation-Score_6" class="Extracellular"/>
<path d="M1725.318,4854.100 A2250.000,2250.000 40.000 0,1 1711.063,4844.218 L1607.948,4991.756 A2430.000,2430.000 0.000 0,0 1623.343,5002.428 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_481_Conservation-Score_9"/>
<path d="M1711.063,4844.218 A2250.000,2250.000 40.000 0,1 1696.885,4834.227 L1631.729,4925.939 A2362.500,2362.500 0.000 0,0 1646.616,4936.429 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_482_Conservation-Score_5" class="Extracellular"/>
<path d="M1696.885,4834.227 A2250.000,2250.000 40.000 0,1 1682.784,4824.128 L1630.095,4897.093 A2340.000,2340.000 0.000 0,0 1644.760,4907.597 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_483_Conservation-Score_4" class="Extracellular"/>
<path d="M1682.784,4824.128 A2250.000,2250.000 40.000 0,1 1668.761,4813.919 L1588.887,4922.754 A2385.000,2385.000 0.000 0,0 1603.751,4933.575 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_484_Conservation-Score_6"/>
<path d="M1668.761,4813.919 A2250.000,2250.000 40.000 0,1 1654.818,4803.603 L1587.559,4893.783 A2362.500,2362.500 0.000 0,0 1602.199,4904.615 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_485_Conservation-Score_5" class="Extracellular"/>
<path d="M1654.818,4803.603 A2250.000,2250.000 40.000 0,1 1640.954,4793.180 L1545.821,4918.702 A2407.500,2407.500 0.000 0,0 1560.655,4929.855 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_486_Conservation-Score_7" class="Extracellular"/>
<path d="M1640.954,4793.180 A2250.000,2250.000 40.000 0,1 1627.171,4782.650 L1531.073,4907.436 A2407.500,2407.500 0.000 0,0 1545.821,4918.702 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_487_Conservation-Score_7"/>
<path d="M1627.171,4782.650 A2250.000,2250.000 40.000 0,1 1613.470,4772.014 L1544.144,4860.615 A2362.500,2362.500 0.000 0,0 1558.530,4871.783 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_488_Conservation-Score_5" class="Extracellular"/>
<path d="M1613.470,4772.014 A2250.000,2250.000 40.000 0,1 1599.851,4761.273 L1543.845,4831.724 A2340.000,2340.000 0.000 0,0 1558.009,4842.895 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_489_Conservation-Score_4" class="Extracellular"/>
<path d="M1599.851,4761.273 A2250.000,2250.000 40.000 0,1 1586.316,4750.427 L1543.905,4802.940 A2317.500,2317.500 0.000 0,0 1557.847,4814.111 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_490_Conservation-Score_2" class="Extracellular"/>
<path d="M1586.316,4750.427 A2250.000,2250.000 40.000 0,1 1572.864,4739.478 L1515.778,4809.057 A2340.000,2340.000 0.000 0,0 1529.768,4820.445 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_491_Conservation-Score_4" class="Extracellular"/>
<path d="M1572.864,4739.478 A2250.000,2250.000 40.000 0,1 1559.497,4728.425 L1487.472,4814.846 A2362.500,2362.500 0.000 0,0 1501.507,4826.452 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_492_Conservation-Score_5" class="Extracellular"/>
<path d="M1559.497,4728.425 A2250.000,2250.000 40.000 0,1 1546.216,4717.269 L1473.527,4803.132 A2362.500,2362.500 0.000 0,0 1487.472,4814.846 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_493_Conservation-Score_5" class="Extracellular"/>
<path d="M1546.216,4717.269 A2250.000,2250.000 40.000 0,1 1533.021,4706.011 L1445.002,4808.371 A2385.000,2385.000 0.000 0,0 1458.989,4820.305 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_494_Conservation-Score_6" class="Extracellular"/>
<path d="M1533.021,4706.011 A2250.000,2250.000 40.000 0,1 1519.913,4694.651 L1445.909,4779.384 A2362.500,2362.500 0.000 0,0 1459.672,4791.311 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_495_Conservation-Score_5"/>
<path d="M1519.913,4694.651 A2250.000,2250.000 40.000 0,1 1506.894,4683.192 L1402.376,4801.015 A2407.500,2407.500 0.000 0,0 1416.307,4813.277 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_496_Conservation-Score_7" class="Extracellular"/>
<path d="M1506.894,4683.192 A2250.000,2250.000 40.000 0,1 1493.963,4671.631 L1448.782,4721.780 A2317.500,2317.500 0.000 0,0 1462.101,4733.687 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_497_Conservation-Score_3"/>
<path d="M1493.963,4671.631 A2250.000,2250.000 40.000 0,1 1481.121,4659.972 L1435.555,4709.771 A2317.500,2317.500 0.000 0,0 1448.782,4721.780 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_498_Conservation-Score_2"/>
<path d="M1481.121,4659.972 A2250.000,2250.000 40.000 0,1 1468.370,4648.214 L1407.105,4714.143 A2340.000,2340.000 0.000 0,0 1420.366,4726.371 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_499_Conservation-Score_4"/>
<path d="M1468.370,4648.214 A2250.000,2250.000 40.000 0,1 1455.710,4636.358 L1409.381,4685.449 A2317.500,2317.500 0.000 0,0 1422.421,4697.661 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_500_Conservation-Score_2"/>
<path d="M1455.710,4636.358 A2250.000,2250.000 40.000 0,1 1443.142,4624.405 L1380.867,4689.381 A2340.000,2340.000 0.000 0,0 1393.938,4701.813 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_501_Conservation-Score_4"/>
<path d="M1443.142,4624.405 A2250.000,2250.000 40.000 0,1 1430.666,4612.355 L1320.812,4725.220 A2407.500,2407.500 0.000 0,0 1334.161,4738.113 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_502_Conservation-Score_7"/>
<path d="M1430.666,4612.355 A2250.000,2250.000 40.000 0,1 1418.283,4600.210 L1307.563,4712.224 A2407.500,2407.500 0.000 0,0 1320.812,4725.220 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_503_Conservation-Score_7" class="Extracellular"/>
<path d="M1418.283,4600.210 A2250.000,2250.000 40.000 0,1 1405.994,4587.969 L1278.474,4715.007 A2430.000,2430.000 0.000 0,0 1291.746,4728.227 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_504_Conservation-Score_9" class="Extracellular"/>
<path d="M1405.994,4587.969 A2250.000,2250.000 40.000 0,1 1393.800,4575.634 L1345.614,4622.903 A2317.500,2317.500 0.000 0,0 1358.174,4635.608 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_505_Conservation-Score_3"/>
<path d="M1393.800,4575.634 A2250.000,2250.000 40.000 0,1 1381.702,4563.206 L1268.421,4672.630 A2407.500,2407.500 0.000 0,0 1281.366,4685.929 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_506_Conservation-Score_7" class="Extracellular"/>
<path d="M1381.702,4563.206 A2250.000,2250.000 40.000 0,1 1369.700,4550.684 L1255.579,4659.232 A2407.500,2407.500 0.000 0,0 1268.421,4672.630 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_507_Conservation-Score_7"/>
<path d="M1369.700,4550.684 A2250.000,2250.000 40.000 0,1 1357.794,4538.070 L1292.106,4599.593 A2340.000,2340.000 0.000 0,0 1304.488,4612.711 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_508_Conservation-Score_4" class="Extracellular"/>
<path d="M1357.794,4538.070 A2250.000,2250.000 40.000 0,1 1345.986,4525.365 L1246.746,4616.887 A2385.000,2385.000 0.000 0,0 1259.262,4630.355 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_509_Conservation-Score_6" class="Extracellular"/>
<path d="M1345.986,4525.365 A2250.000,2250.000 40.000 0,1 1334.277,4512.570 L1267.648,4573.072 A2340.000,2340.000 0.000 0,0 1279.826,4586.380 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_510_Conservation-Score_4" class="Extracellular"/>
<path d="M1334.277,4512.570 A2250.000,2250.000 40.000 0,1 1322.666,4499.684 L1238.800,4574.668 A2362.500,2362.500 0.000 0,0 1250.991,4588.198 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_511_Conservation-Score_5"/>
<path d="M1322.666,4499.684 A2250.000,2250.000 40.000 0,1 1311.155,4486.709 L1226.713,4561.045 A2362.500,2362.500 0.000 0,0 1238.800,4574.668 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_512_Conservation-Score_5"/>
<path d="M1311.155,4486.709 A2250.000,2250.000 40.000 0,1 1299.745,4473.646 L1214.732,4547.328 A2362.500,2362.500 0.000 0,0 1226.713,4561.045 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_513_Conservation-Score_5" class="Extracellular"/>
<path d="M1299.745,4473.646 A2250.000,2250.000 40.000 0,1 1288.436,4460.495 L1117.279,4606.545 A2475.000,2475.000 0.000 0,0 1129.719,4621.011 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_514_Conservation-Score_11" class="Extracellular"/>
<path d="M1288.436,4460.495 A2250.000,2250.000 40.000 0,1 1277.228,4447.258 L1104.951,4591.984 A2475.000,2475.000 0.000 0,0 1117.279,4606.545 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_515_Conservation-Score_11"/>
<path d="M1277.228,4447.258 A2250.000,2250.000 40.000 0,1 1266.122,4433.935 L1144.751,4534.310 A2407.500,2407.500 0.000 0,0 1156.634,4548.566 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_516_Conservation-Score_7" class="Extracellular"/>
<path d="M1266.122,4433.935 A2250.000,2250.000 40.000 0,1 1255.120,4420.526 L1132.978,4519.963 A2407.500,2407.500 0.000 0,0 1144.751,4534.310 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_517_Conservation-Score_7"/>
<path d="M1255.120,4420.526 A2250.000,2250.000 40.000 0,1 1244.221,4407.033 L1068.644,4547.736 A2475.000,2475.000 0.000 0,0 1080.632,4562.579 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_518_Conservation-Score_11"/>
<path d="M1244.221,4407.033 A2250.000,2250.000 40.000 0,1 1233.427,4393.456 L1092.101,4504.933 A2430.000,2430.000 0.000 0,0 1103.759,4519.595 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_519_Conservation-Score_8" class="Extracellular"/>
<path d="M1233.427,4393.456 A2250.000,2250.000 40.000 0,1 1222.738,4379.797 L1133.875,4448.787 A2362.500,2362.500 0.000 0,0 1145.098,4463.129 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_520_Conservation-Score_5"/>
<path d="M1222.738,4379.797 A2250.000,2250.000 40.000 0,1 1212.154,4366.055 L1087.005,4461.679 A2407.500,2407.500 0.000 0,0 1098.329,4476.382 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_521_Conservation-Score_7"/>
<path d="M1212.154,4366.055 A2250.000,2250.000 40.000 0,1 1201.677,4352.233 L1021.844,4487.456 A2475.000,2475.000 0.000 0,0 1033.369,4502.661 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_522_Conservation-Score_11"/>
<path d="M1201.677,4352.233 A2250.000,2250.000 40.000 0,1 1191.306,4338.329 L1064.697,4432.013 A2407.500,2407.500 0.000 0,0 1075.794,4446.889 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_523_Conservation-Score_7" class="Extracellular"/>
<path d="M1191.306,4338.329 A2250.000,2250.000 40.000 0,1 1181.043,4324.347 L1071.905,4403.808 A2385.000,2385.000 0.000 0,0 1082.784,4418.629 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_524_Conservation-Score_6"/>
<path d="M1181.043,4324.347 A2250.000,2250.000 40.000 0,1 1170.888,4310.286 L1024.559,4415.109 A2430.000,2430.000 0.000 0,0 1035.526,4430.295 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_525_Conservation-Score_8"/>
<path d="M1170.888,4310.286 A2250.000,2250.000 40.000 0,1 1160.841,4296.147 L1087.275,4347.992 A2340.000,2340.000 0.000 0,0 1097.723,4362.697 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_526_Conservation-Score_4"/>
<path d="M1160.841,4296.147 A2250.000,2250.000 40.000 0,1 1150.904,4281.930 L1002.977,4384.485 A2430.000,2430.000 0.000 0,0 1013.709,4399.838 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_527_Conservation-Score_9" class="Extracellular"/>
<path d="M1150.904,4281.930 A2250.000,2250.000 40.000 0,1 1141.077,4267.638 L1085.310,4305.667 A2317.500,2317.500 0.000 0,0 1095.432,4320.388 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_528_Conservation-Score_3" class="Extracellular"/>
<path d="M1141.077,4267.638 A2250.000,2250.000 40.000 0,1 1131.361,4253.270 L1075.301,4290.869 A2317.500,2317.500 0.000 0,0 1085.310,4305.667 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_529_Conservation-Score_2" class="Extracellular"/>
<path d="M1131.361,4253.270 A2250.000,2250.000 40.000 0,1 1121.755,4238.828 L1065.408,4275.993 A2317.500,2317.500 0.000 0,0 1075.301,4290.869 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_530_Conservation-Score_2"/>
<path d="M1121.755,4238.828 A2250.000,2250.000 40.000 0,1 1112.261,4224.313 L1074.506,4248.799 A2295.000,2295.000 0.000 0,0 1084.190,4263.605 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_531_Conservation-Score_1" class="Extracellular"/>
<path d="M1112.261,4224.313 A2250.000,2250.000 40.000 0,1 1102.879,4209.724 L1064.937,4233.918 A2295.000,2295.000 0.000 0,0 1074.506,4248.799 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_532_Conservation-Score_1"/>
<path d="M1102.879,4209.724 A2250.000,2250.000 40.000 0,1 1093.610,4195.064 L1036.418,4230.916 A2317.500,2317.500 0.000 0,0 1045.965,4246.016 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_533_Conservation-Score_3"/>
<path d="M1093.610,4195.064 A2250.000,2250.000 40.000 0,1 1084.454,4180.332 L1007.832,4227.545 A2340.000,2340.000 0.000 0,0 1017.354,4242.866 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_534_Conservation-Score_4" class="Extracellular"/>
<path d="M1084.454,4180.332 A2250.000,2250.000 40.000 0,1 1075.412,4165.531 L1017.675,4200.497 A2317.500,2317.500 0.000 0,0 1026.988,4215.742 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_535_Conservation-Score_3"/>
<path d="M1075.412,4165.531 A2250.000,2250.000 40.000 0,1 1066.485,4150.660 L1027.814,4173.673 A2295.000,2295.000 0.000 0,0 1036.920,4188.841 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_536_Conservation-Score_1" class="Extracellular"/>
<path d="M1066.485,4150.660 A2250.000,2250.000 40.000 0,1 1057.672,4135.721 L999.402,4169.792 A2317.500,2317.500 0.000 0,0 1008.479,4185.180 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_537_Conservation-Score_3"/>
<path d="M1057.672,4135.721 A2250.000,2250.000 40.000 0,1 1048.975,4120.714 L990.444,4154.335 A2317.500,2317.500 0.000 0,0 999.402,4169.792 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_538_Conservation-Score_3"/>
<path d="M1048.975,4120.714 A2250.000,2250.000 40.000 0,1 1040.393,4105.641 L922.817,4171.979 A2385.000,2385.000 0.000 0,0 931.913,4187.957 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_539_Conservation-Score_6"/>
<path d="M1040.393,4105.641 A2250.000,2250.000 40.000 0,1 1031.928,4090.502 L894.163,4166.837 A2407.500,2407.500 0.000 0,0 903.221,4183.035 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_540_Conservation-Score_7"/>
<path d="M1031.928,4090.502 A2250.000,2250.000 40.000 0,1 1023.580,4075.298 L944.524,4118.310 A2340.000,2340.000 0.000 0,0 953.205,4134.122 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_541_Conservation-Score_4" class="Extracellular"/>
<path d="M1023.580,4075.298 A2250.000,2250.000 40.000 0,1 1015.350,4060.030 L816.885,4166.033 A2475.000,2475.000 0.000 0,0 825.938,4182.828 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_542_Conservation-Score_11"/>
<path d="M1015.350,4060.030 A2250.000,2250.000 40.000 0,1 1007.237,4044.699 L867.744,4117.828 A2407.500,2407.500 0.000 0,0 876.424,4134.232 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_543_Conservation-Score_7"/>
<path d="M1007.237,4044.699 A2250.000,2250.000 40.000 0,1 999.243,4029.307 L839.183,4111.651 A2430.000,2430.000 0.000 0,0 847.816,4128.275 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_544_Conservation-Score_8" class="Extracellular"/>
<path d="M999.243,4029.307 A2250.000,2250.000 40.000 0,1 991.368,4013.853 L951.195,4034.130 A2295.000,2295.000 0.000 0,0 959.228,4049.893 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_545_Conservation-Score_1" class="Extracellular"/>
<path d="M991.368,4013.853 A2250.000,2250.000 40.000 0,1 983.612,3998.339 L943.284,4018.305 A2295.000,2295.000 0.000 0,0 951.195,4034.130 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_546_Conservation-Score_1"/>
<path d="M983.612,3998.339 A2250.000,2250.000 40.000 0,1 975.976,3982.765 L834.294,4051.559 A2407.500,2407.500 0.000 0,0 842.465,4068.222 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_547_Conservation-Score_7"/>
<path d="M975.976,3982.765 A2250.000,2250.000 40.000 0,1 968.460,3967.133 L846.568,4025.161 A2385.000,2385.000 0.000 0,0 854.535,4041.731 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_548_Conservation-Score_6" class="Extracellular"/>
<path d="M968.460,3967.133 A2250.000,2250.000 40.000 0,1 961.065,3951.444 L818.340,4018.045 A2407.500,2407.500 0.000 0,0 826.253,4034.832 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_549_Conservation-Score_7"/>
<path d="M961.065,3951.444 A2250.000,2250.000 40.000 0,1 953.791,3935.698 L871.943,3973.126 A2340.000,2340.000 0.000 0,0 879.508,3989.501 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_550_Conservation-Score_4" class="Extracellular"/>
<path d="M953.791,3935.698 A2250.000,2250.000 40.000 0,1 946.639,3919.896 L802.904,3984.289 A2407.500,2407.500 0.000 0,0 810.557,4001.197 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_551_Conservation-Score_7" class="Extracellular"/>
<path d="M946.639,3919.896 A2250.000,2250.000 40.000 0,1 939.609,3904.040 L857.193,3940.202 A2340.000,2340.000 0.000 0,0 864.505,3956.692 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_552_Conservation-Score_4"/>
<path d="M939.609,3904.040 A2250.000,2250.000 40.000 0,1 932.701,3888.130 L767.317,3959.181 A2430.000,2430.000 0.000 0,0 774.778,3976.363 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_553_Conservation-Score_9" class="Extracellular"/>
<path d="M932.701,3888.130 A2250.000,2250.000 40.000 0,1 925.916,3872.167 L801.471,3924.497 A2385.000,2385.000 0.000 0,0 808.663,3941.418 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_554_Conservation-Score_6" class="Extracellular"/>
<path d="M925.916,3872.167 A2250.000,2250.000 40.000 0,1 919.254,3856.153 L815.217,3898.961 A2362.500,2362.500 0.000 0,0 822.212,3915.776 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_555_Conservation-Score_5"/>
<path d="M919.254,3856.153 A2250.000,2250.000 40.000 0,1 912.716,3840.087 L808.352,3882.092 A2362.500,2362.500 0.000 0,0 815.217,3898.961 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_556_Conservation-Score_5"/>
<path d="M912.716,3840.087 A2250.000,2250.000 40.000 0,1 906.302,3823.972 L738.807,3889.890 A2430.000,2430.000 0.000 0,0 745.734,3907.294 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_557_Conservation-Score_9"/>
<path d="M906.302,3823.972 A2250.000,2250.000 40.000 0,1 900.013,3807.808 L774.013,3856.276 A2385.000,2385.000 0.000 0,0 780.680,3873.410 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_558_Conservation-Score_6"/>
<path d="M900.013,3807.808 A2250.000,2250.000 40.000 0,1 893.848,3791.596 L788.540,3831.175 A2362.500,2362.500 0.000 0,0 795.013,3848.198 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_559_Conservation-Score_5" class="Extracellular"/>
<path d="M893.848,3791.596 A2250.000,2250.000 40.000 0,1 887.808,3775.336 L782.199,3814.103 A2362.500,2362.500 0.000 0,0 788.540,3831.175 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_560_Conservation-Score_5" class="Extracellular"/>
<path d="M887.808,3775.336 A2250.000,2250.000 40.000 0,1 881.894,3759.031 L797.170,3789.392 A2340.000,2340.000 0.000 0,0 803.321,3806.350 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_561_Conservation-Score_4" class="Extracellular"/>
<path d="M881.894,3759.031 A2250.000,2250.000 40.000 0,1 876.106,3742.680 L791.150,3772.387 A2340.000,2340.000 0.000 0,0 797.170,3789.392 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_562_Conservation-Score_4" class="Extracellular"/>
<path d="M876.106,3742.680 A2250.000,2250.000 40.000 0,1 870.444,3726.286 L700.079,3784.388 A2430.000,2430.000 0.000 0,0 706.194,3802.095 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_563_Conservation-Score_8"/>
<path d="M870.444,3726.286 A2250.000,2250.000 40.000 0,1 864.908,3709.848 L800.856,3731.143 A2317.500,2317.500 0.000 0,0 806.557,3748.074 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_564_Conservation-Score_2" class="Extracellular"/>
<path d="M864.908,3709.848 A2250.000,2250.000 40.000 0,1 859.500,3693.368 L795.285,3714.169 A2317.500,2317.500 0.000 0,0 800.856,3731.143 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_565_Conservation-Score_2"/>
<path d="M859.500,3693.368 A2250.000,2250.000 40.000 0,1 854.218,3676.847 L789.845,3697.152 A2317.500,2317.500 0.000 0,0 795.285,3714.169 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_566_Conservation-Score_3" class="Extracellular"/>
<path d="M854.218,3676.847 A2250.000,2250.000 40.000 0,1 849.064,3660.285 L784.536,3680.094 A2317.500,2317.500 0.000 0,0 789.845,3697.152 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_567_Conservation-Score_3"/>
<path d="M849.064,3660.285 A2250.000,2250.000 40.000 0,1 844.038,3643.684 L800.919,3656.558 A2295.000,2295.000 0.000 0,0 806.046,3673.491 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_568_Conservation-Score_1" class="Extracellular"/>
<path d="M844.038,3643.684 A2250.000,2250.000 40.000 0,1 839.140,3627.045 L774.315,3645.857 A2317.500,2317.500 0.000 0,0 779.360,3662.995 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_569_Conservation-Score_3"/>
<path d="M839.140,3627.045 A2250.000,2250.000 40.000 0,1 834.371,3610.369 L769.402,3628.680 A2317.500,2317.500 0.000 0,0 774.315,3645.857 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_570_Conservation-Score_2" class="Extracellular"/>
<path d="M834.371,3610.369 A2250.000,2250.000 40.000 0,1 829.730,3593.657 L764.622,3611.467 A2317.500,2317.500 0.000 0,0 769.402,3628.680 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_571_Conservation-Score_3"/>
<path d="M829.730,3593.657 A2250.000,2250.000 40.000 0,1 825.218,3576.909 L781.723,3588.447 A2295.000,2295.000 0.000 0,0 786.325,3605.530 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_572_Conservation-Score_1"/>
<path d="M825.218,3576.909 A2250.000,2250.000 40.000 0,1 820.836,3560.127 L755.461,3576.931 A2317.500,2317.500 0.000 0,0 759.975,3594.216 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_573_Conservation-Score_2"/>
<path d="M820.836,3560.127 A2250.000,2250.000 40.000 0,1 816.582,3543.312 L751.080,3559.611 A2317.500,2317.500 0.000 0,0 755.461,3576.931 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_574_Conservation-Score_3" class="Extracellular"/>
<path d="M816.582,3543.312 A2250.000,2250.000 40.000 0,1 812.459,3526.464 L703.082,3552.787 A2362.500,2362.500 0.000 0,0 707.412,3570.477 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_575_Conservation-Score_5" class="Extracellular"/>
<path d="M812.459,3526.464 A2250.000,2250.000 40.000 0,1 808.466,3509.585 L742.720,3524.873 A2317.500,2317.500 0.000 0,0 746.833,3542.258 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_576_Conservation-Score_3"/>
<path d="M808.466,3509.585 A2250.000,2250.000 40.000 0,1 804.603,3492.676 L716.787,3512.383 A2340.000,2340.000 0.000 0,0 720.804,3529.969 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_577_Conservation-Score_4" class="Extracellular"/>
<path d="M804.603,3492.676 A2250.000,2250.000 40.000 0,1 800.870,3475.738 L668.922,3504.282 A2385.000,2385.000 0.000 0,0 672.879,3522.237 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_578_Conservation-Score_6"/>
<path d="M800.870,3475.738 A2250.000,2250.000 40.000 0,1 797.268,3458.771 L753.213,3467.946 A2295.000,2295.000 0.000 0,0 756.887,3485.252 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_579_Conservation-Score_1"/>
<path d="M797.268,3458.771 A2250.000,2250.000 40.000 0,1 793.797,3441.777 L705.549,3459.448 A2340.000,2340.000 0.000 0,0 709.159,3477.122 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_580_Conservation-Score_4"/>
<path d="M793.797,3441.777 A2250.000,2250.000 40.000 0,1 790.457,3424.757 L679.980,3445.995 A2362.500,2362.500 0.000 0,0 683.487,3463.866 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_581_Conservation-Score_5" class="Extracellular"/>
<path d="M790.457,3424.757 A2250.000,2250.000 40.000 0,1 787.248,3407.711 L676.610,3428.097 A2362.500,2362.500 0.000 0,0 679.980,3445.995 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_582_Conservation-Score_5"/>
<path d="M787.248,3407.711 A2250.000,2250.000 40.000 0,1 784.171,3390.642 L562.588,3429.706 A2475.000,2475.000 0.000 0,0 565.973,3448.483 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_583_Conservation-Score_11" class="Extracellular"/>
<path d="M784.171,3390.642 A2250.000,2250.000 40.000 0,1 781.225,3373.549 L603.723,3403.433 A2430.000,2430.000 0.000 0,0 606.904,3421.893 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_584_Conservation-Score_8"/>
<path d="M781.225,3373.549 A2250.000,2250.000 40.000 0,1 778.412,3356.434 L622.900,3381.384 A2407.500,2407.500 0.000 0,0 625.911,3399.697 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_585_Conservation-Score_7" class="Extracellular"/>
<path d="M778.412,3356.434 A2250.000,2250.000 40.000 0,1 775.730,3339.297 L664.516,3356.262 A2362.500,2362.500 0.000 0,0 667.332,3374.255 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_586_Conservation-Score_5" class="Extracellular"/>
<path d="M775.730,3339.297 A2250.000,2250.000 40.000 0,1 773.180,3322.141 L661.839,3338.248 A2362.500,2362.500 0.000 0,0 664.516,3356.262 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_587_Conservation-Score_5"/>
<path d="M773.180,3322.141 A2250.000,2250.000 40.000 0,1 770.763,3304.965 L547.840,3335.462 A2475.000,2475.000 0.000 0,0 550.499,3354.355 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_588_Conservation-Score_11"/>
<path d="M770.763,3304.965 A2250.000,2250.000 40.000 0,1 768.479,3287.772 L679.218,3299.282 A2340.000,2340.000 0.000 0,0 681.594,3317.164 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_589_Conservation-Score_4"/>
<path d="M768.479,3287.772 A2250.000,2250.000 40.000 0,1 766.327,3270.561 L654.643,3284.089 A2362.500,2362.500 0.000 0,0 656.903,3302.160 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_590_Conservation-Score_5" class="Extracellular"/>
<path d="M766.327,3270.561 A2250.000,2250.000 40.000 0,1 764.307,3253.334 L652.523,3266.001 A2362.500,2362.500 0.000 0,0 654.643,3284.089 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_591_Conservation-Score_5" class="Extracellular"/>
<path d="M764.307,3253.334 A2250.000,2250.000 40.000 0,1 762.421,3236.092 L672.918,3245.536 A2340.000,2340.000 0.000 0,0 674.880,3263.467 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_592_Conservation-Score_4" class="Extracellular"/>
<path d="M762.421,3236.092 A2250.000,2250.000 40.000 0,1 760.667,3218.836 L671.094,3227.589 A2340.000,2340.000 0.000 0,0 672.918,3245.536 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_593_Conservation-Score_4" class="Extracellular"/>
<path d="M760.667,3218.836 A2250.000,2250.000 40.000 0,1 759.047,3201.567 L602.180,3215.677 A2407.500,2407.500 0.000 0,0 603.914,3234.154 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_594_Conservation-Score_7" class="Extracellular"/>
<path d="M759.047,3201.567 A2250.000,2250.000 40.000 0,1 757.560,3184.286 L645.438,3193.500 A2362.500,2362.500 0.000 0,0 646.999,3211.645 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_595_Conservation-Score_5"/>
<path d="M757.560,3184.286 A2250.000,2250.000 40.000 0,1 756.206,3166.994 L644.016,3175.344 A2362.500,2362.500 0.000 0,0 645.438,3193.500 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_596_Conservation-Score_5"/>
<path d="M756.206,3166.994 A2250.000,2250.000 40.000 0,1 754.985,3149.692 L642.734,3157.177 A2362.500,2362.500 0.000 0,0 644.016,3175.344 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_597_Conservation-Score_5" class="Extracellular"/>
<path d="M754.985,3149.692 A2250.000,2250.000 40.000 0,1 753.898,3132.382 L574.210,3142.972 A2430.000,2430.000 0.000 0,0 575.384,3161.668 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_598_Conservation-Score_8"/>
<path d="M753.898,3132.382 A2250.000,2250.000 40.000 0,1 752.944,3115.063 L595.650,3123.117 A2407.500,2407.500 0.000 0,0 596.671,3141.648 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_599_Conservation-Score_7"/>
<path d="M752.944,3115.063 A2250.000,2250.000 40.000 0,1 752.124,3097.737 L572.294,3105.556 A2430.000,2430.000 0.000 0,0 573.180,3124.268 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_600_Conservation-Score_9"/>
<path d="M752.124,3097.737 A2250.000,2250.000 40.000 0,1 751.437,3080.406 L594.038,3086.035 A2407.500,2407.500 0.000 0,0 594.772,3104.579 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_601_Conservation-Score_7"/>
<path d="M751.437,3080.406 A2250.000,2250.000 40.000 0,1 750.884,3063.070 L638.428,3066.224 A2362.500,2362.500 0.000 0,0 639.009,3084.427 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_602_Conservation-Score_5" class="Extracellular"/>
<path d="M750.884,3063.070 A2250.000,2250.000 40.000 0,1 750.465,3045.730 L592.997,3048.932 A2407.500,2407.500 0.000 0,0 593.446,3067.485 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_603_Conservation-Score_7" class="Extracellular"/>
<path d="M750.465,3045.730 A2250.000,2250.000 40.000 0,1 750.179,3028.388 L570.193,3030.659 A2430.000,2430.000 0.000 0,0 570.502,3049.389 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_604_Conservation-Score_8"/>
<path d="M750.179,3028.388 A2250.000,2250.000 40.000 0,1 750.027,3011.044 L525.030,3012.148 A2475.000,2475.000 0.000 0,0 525.197,3031.227 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_605_Conservation-Score_11"/>
<path d="M750.027,3011.044 A2250.000,2250.000 40.000 0,1 750.009,2993.699 L615.009,2993.321 A2385.000,2385.000 0.000 0,0 615.029,3011.706 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_606_Conservation-Score_6"/>
<path d="M750.009,2993.699 A2250.000,2250.000 40.000 0,1 750.124,2976.354 L660.129,2975.409 A2340.000,2340.000 0.000 0,0 660.009,2993.447 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_607_Conservation-Score_4" class="Extracellular"/>
<path d="M750.124,2976.354 A2250.000,2250.000 40.000 0,1 750.373,2959.011 L682.885,2957.782 A2317.500,2317.500 0.000 0,0 682.628,2975.645 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_608_Conservation-Score_3"/>
<path d="M750.373,2959.011 A2250.000,2250.000 40.000 0,1 750.756,2941.671 L683.279,2939.921 A2317.500,2317.500 0.000 0,0 682.885,2957.782 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_609_Conservation-Score_3" class="Extracellular"/>
<path d="M750.756,2941.671 A2250.000,2250.000 40.000 0,1 751.273,2924.334 L683.811,2922.064 A2317.500,2317.500 0.000 0,0 683.279,2939.921 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_610_Conservation-Score_3"/>
<path d="M751.273,2924.334 A2250.000,2250.000 40.000 0,1 751.923,2907.001 L706.961,2905.141 A2295.000,2295.000 0.000 0,0 706.298,2922.820 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_611_Conservation-Score_1" class="Extracellular"/>
<path d="M751.923,2907.001 A2250.000,2250.000 40.000 0,1 752.706,2889.674 L685.288,2886.364 A2317.500,2317.500 0.000 0,0 684.480,2904.211 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_612_Conservation-Score_2" class="Extracellular"/>
<path d="M752.706,2889.674 A2250.000,2250.000 40.000 0,1 753.624,2872.353 L686.232,2868.524 A2317.500,2317.500 0.000 0,0 685.288,2886.364 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_613_Conservation-Score_3"/>
<path d="M753.624,2872.353 A2250.000,2250.000 40.000 0,1 754.674,2855.040 L687.315,2850.692 A2317.500,2317.500 0.000 0,0 686.232,2868.524 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_614_Conservation-Score_2" class="Extracellular"/>
<path d="M754.674,2855.040 A2250.000,2250.000 40.000 0,1 755.859,2837.736 L666.093,2831.245 A2340.000,2340.000 0.000 0,0 664.861,2849.242 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_615_Conservation-Score_4"/>
<path d="M755.859,2837.736 A2250.000,2250.000 40.000 0,1 757.176,2820.441 L712.320,2816.850 A2295.000,2295.000 0.000 0,0 710.976,2834.491 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_616_Conservation-Score_1"/>
<path d="M757.176,2820.441 A2250.000,2250.000 40.000 0,1 758.627,2803.157 L691.386,2797.252 A2317.500,2317.500 0.000 0,0 689.891,2815.054 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_617_Conservation-Score_3"/>
<path d="M758.627,2803.157 A2250.000,2250.000 40.000 0,1 760.211,2785.885 L693.017,2779.461 A2317.500,2317.500 0.000 0,0 691.386,2797.252 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_618_Conservation-Score_2" class="Extracellular"/>
<path d="M760.211,2785.885 A2250.000,2250.000 40.000 0,1 761.928,2768.625 L672.405,2759.370 A2340.000,2340.000 0.000 0,0 670.619,2777.320 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_619_Conservation-Score_4"/>
<path d="M761.928,2768.625 A2250.000,2250.000 40.000 0,1 763.778,2751.379 L696.692,2743.921 A2317.500,2317.500 0.000 0,0 694.786,2761.684 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_620_Conservation-Score_3" class="Extracellular"/>
<path d="M763.778,2751.379 A2250.000,2250.000 40.000 0,1 765.761,2734.148 L698.734,2726.173 A2317.500,2317.500 0.000 0,0 696.692,2743.921 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_621_Conservation-Score_3"/>
<path d="M765.761,2734.148 A2250.000,2250.000 40.000 0,1 767.877,2716.933 L700.913,2708.441 A2317.500,2317.500 0.000 0,0 698.734,2726.173 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_622_Conservation-Score_2"/>
<path d="M767.877,2716.933 A2250.000,2250.000 40.000 0,1 770.125,2699.734 L703.229,2690.726 A2317.500,2317.500 0.000 0,0 700.913,2708.441 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_623_Conservation-Score_3"/>
<path d="M770.125,2699.734 A2250.000,2250.000 40.000 0,1 772.506,2682.554 L705.682,2673.030 A2317.500,2317.500 0.000 0,0 703.229,2690.726 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_624_Conservation-Score_2"/>
<path d="M772.506,2682.554 A2250.000,2250.000 40.000 0,1 775.020,2665.392 L686.020,2652.008 A2340.000,2340.000 0.000 0,0 683.407,2669.856 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_625_Conservation-Score_4"/>
<path d="M775.020,2665.392 A2250.000,2250.000 40.000 0,1 777.665,2648.250 L710.995,2637.697 A2317.500,2317.500 0.000 0,0 708.270,2655.354 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_626_Conservation-Score_3" class="Extracellular"/>
<path d="M777.665,2648.250 A2250.000,2250.000 40.000 0,1 780.443,2631.129 L713.856,2620.063 A2317.500,2317.500 0.000 0,0 710.995,2637.697 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_627_Conservation-Score_3"/>
<path d="M780.443,2631.129 A2250.000,2250.000 40.000 0,1 783.352,2614.030 L716.853,2602.451 A2317.500,2317.500 0.000 0,0 713.856,2620.063 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_628_Conservation-Score_2"/>
<path d="M783.352,2614.030 A2250.000,2250.000 40.000 0,1 786.394,2596.954 L719.985,2584.862 A2317.500,2317.500 0.000 0,0 716.853,2602.451 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_629_Conservation-Score_3" class="Extracellular"/>
<path d="M786.394,2596.954 A2250.000,2250.000 40.000 0,1 789.566,2579.902 L767.462,2575.701 A2272.500,2272.500 0.000 0,0 764.257,2592.923 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_630_Conservation-Score_0"/>
<path d="M789.566,2579.902 A2250.000,2250.000 40.000 0,1 792.870,2562.874 L748.728,2554.132 A2295.000,2295.000 0.000 0,0 745.358,2571.500 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_631_Conservation-Score_1" class="Extracellular"/>
<path d="M792.870,2562.874 A2250.000,2250.000 40.000 0,1 796.306,2545.873 L730.195,2532.249 A2317.500,2317.500 0.000 0,0 726.656,2549.761 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_632_Conservation-Score_3" class="Extracellular"/>
<path d="M796.306,2545.873 A2250.000,2250.000 40.000 0,1 799.872,2528.899 L733.868,2514.766 A2317.500,2317.500 0.000 0,0 730.195,2532.249 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_633_Conservation-Score_3" class="Extracellular"/>
<path d="M799.872,2528.899 A2250.000,2250.000 40.000 0,1 803.569,2511.953 L737.676,2497.311 A2317.500,2317.500 0.000 0,0 733.868,2514.766 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_634_Conservation-Score_3" class="Extracellular"/>
<path d="M803.569,2511.953 A2250.000,2250.000 40.000 0,1 807.396,2495.035 L741.618,2479.886 A2317.500,2317.500 0.000 0,0 737.676,2497.311 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_635_Conservation-Score_3"/>
<path d="M807.396,2495.035 A2250.000,2250.000 40.000 0,1 811.354,2478.148 L745.695,2462.492 A2317.500,2317.500 0.000 0,0 741.618,2479.886 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_636_Conservation-Score_2"/>
<path d="M811.354,2478.148 A2250.000,2250.000 40.000 0,1 815.442,2461.292 L749.905,2445.131 A2317.500,2317.500 0.000 0,0 745.695,2462.492 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_637_Conservation-Score_2" class="Extracellular"/>
<path d="M815.442,2461.292 A2250.000,2250.000 40.000 0,1 819.660,2444.468 L754.250,2427.802 A2317.500,2317.500 0.000 0,0 749.905,2445.131 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_638_Conservation-Score_2" class="Extracellular"/>
<path d="M819.660,2444.468 A2250.000,2250.000 40.000 0,1 824.007,2427.676 L758.727,2410.507 A2317.500,2317.500 0.000 0,0 754.250,2427.802 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_639_Conservation-Score_3"/>
<path d="M824.007,2427.676 A2250.000,2250.000 40.000 0,1 828.484,2410.919 L785.053,2399.138 A2295.000,2295.000 0.000 0,0 780.487,2416.230 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_640_Conservation-Score_1" class="Extracellular"/>
<path d="M828.484,2410.919 A2250.000,2250.000 40.000 0,1 833.089,2394.197 L768.082,2376.023 A2317.500,2317.500 0.000 0,0 763.338,2393.247 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_641_Conservation-Score_2" class="Extracellular"/>
<path d="M833.089,2394.197 A2250.000,2250.000 40.000 0,1 837.824,2377.511 L772.958,2358.836 A2317.500,2317.500 0.000 0,0 768.082,2376.023 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_642_Conservation-Score_2"/>
<path d="M837.824,2377.511 A2250.000,2250.000 40.000 0,1 842.686,2360.862 L777.967,2341.687 A2317.500,2317.500 0.000 0,0 772.958,2358.836 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_643_Conservation-Score_2"/>
<path d="M842.686,2360.862 A2250.000,2250.000 40.000 0,1 847.677,2344.250 L804.631,2331.135 A2295.000,2295.000 0.000 0,0 799.540,2348.079 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_644_Conservation-Score_1"/>
<path d="M847.677,2344.250 A2250.000,2250.000 40.000 0,1 852.796,2327.678 L788.380,2307.508 A2317.500,2317.500 0.000 0,0 783.108,2324.578 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_645_Conservation-Score_3"/>
<path d="M852.796,2327.678 A2250.000,2250.000 40.000 0,1 858.043,2311.146 L793.784,2290.480 A2317.500,2317.500 0.000 0,0 788.380,2307.508 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_646_Conservation-Score_3" class="Extracellular"/>
<path d="M858.043,2311.146 A2250.000,2250.000 40.000 0,1 863.417,2294.654 L799.319,2273.494 A2317.500,2317.500 0.000 0,0 793.784,2290.480 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_647_Conservation-Score_2" class="Extracellular"/>
<path d="M863.417,2294.654 A2250.000,2250.000 40.000 0,1 868.918,2278.205 L804.985,2256.551 A2317.500,2317.500 0.000 0,0 799.319,2273.494 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_648_Conservation-Score_3"/>
<path d="M868.918,2278.205 A2250.000,2250.000 40.000 0,1 874.545,2261.798 L810.781,2239.652 A2317.500,2317.500 0.000 0,0 804.985,2256.551 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_649_Conservation-Score_3"/>
<path d="M874.545,2261.798 A2250.000,2250.000 40.000 0,1 880.299,2245.436 L816.708,2222.799 A2317.500,2317.500 0.000 0,0 810.781,2239.652 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_650_Conservation-Score_3"/>
<path d="M880.299,2245.436 A2250.000,2250.000 40.000 0,1 886.179,2229.118 L843.902,2213.700 A2295.000,2295.000 0.000 0,0 837.905,2230.344 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_651_Conservation-Score_1"/>
<path d="M886.179,2229.118 A2250.000,2250.000 40.000 0,1 892.184,2212.846 L828.950,2189.231 A2317.500,2317.500 0.000 0,0 822.764,2205.991 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_652_Conservation-Score_3"/>
<path d="M892.184,2212.846 A2250.000,2250.000 40.000 0,1 898.315,2196.621 L856.281,2180.553 A2295.000,2295.000 0.000 0,0 850.028,2197.103 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_653_Conservation-Score_1" class="Extracellular"/>
<path d="M898.315,2196.621 A2250.000,2250.000 40.000 0,1 904.570,2180.443 L841.707,2155.856 A2317.500,2317.500 0.000 0,0 835.264,2172.519 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_654_Conservation-Score_3"/>
<path d="M904.570,2180.443 A2250.000,2250.000 40.000 0,1 910.950,2164.314 L848.279,2139.244 A2317.500,2317.500 0.000 0,0 841.707,2155.856 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_655_Conservation-Score_2" class="Extracellular"/>
<path d="M910.950,2164.314 A2250.000,2250.000 40.000 0,1 917.454,2148.235 L896.629,2139.717 A2272.500,2272.500 0.000 0,0 890.060,2155.957 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_656_Conservation-Score_0" class="Extracellular"/>
<path d="M917.454,2148.235 A2250.000,2250.000 40.000 0,1 924.082,2132.206 L903.323,2123.529 A2272.500,2272.500 0.000 0,0 896.629,2139.717 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_657_Conservation-Score_0"/>
<path d="M924.082,2132.206 A2250.000,2250.000 40.000 0,1 930.834,2116.230 L910.142,2107.392 A2272.500,2272.500 0.000 0,0 903.323,2123.529 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_658_Conservation-Score_0" class="Extracellular"/>
<path d="M930.834,2116.230 A2250.000,2250.000 40.000 0,1 937.708,2100.305 L875.839,2073.314 A2317.500,2317.500 0.000 0,0 868.759,2089.716 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_659_Conservation-Score_3"/>
<path d="M937.708,2100.305 A2250.000,2250.000 40.000 0,1 944.705,2084.434 L883.046,2056.967 A2317.500,2317.500 0.000 0,0 875.839,2073.314 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_660_Conservation-Score_2" class="Extracellular"/>
<path d="M944.705,2084.434 A2250.000,2250.000 40.000 0,1 951.824,2068.617 L910.860,2049.990 A2295.000,2295.000 0.000 0,0 903.599,2066.123 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_661_Conservation-Score_1"/>
<path d="M951.824,2068.617 A2250.000,2250.000 40.000 0,1 959.064,2052.856 L918.246,2033.913 A2295.000,2295.000 0.000 0,0 910.860,2049.990 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_662_Conservation-Score_1" class="Extracellular"/>
<path d="M959.064,2052.856 A2250.000,2250.000 40.000 0,1 966.426,2037.151 L905.419,2008.266 A2317.500,2317.500 0.000 0,0 897.836,2024.442 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_663_Conservation-Score_2"/>
<path d="M966.426,2037.151 A2250.000,2250.000 40.000 0,1 973.909,2021.504 L953.648,2011.719 A2272.500,2272.500 0.000 0,0 946.090,2027.523 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_664_Conservation-Score_0" class="Extracellular"/>
<path d="M973.909,2021.504 A2250.000,2250.000 40.000 0,1 981.512,2005.914 L920.958,1976.091 A2317.500,2317.500 0.000 0,0 913.126,1992.149 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_665_Conservation-Score_2" class="Extracellular"/>
<path d="M981.512,2005.914 A2250.000,2250.000 40.000 0,1 989.235,1990.383 L949.020,1970.191 A2295.000,2295.000 0.000 0,0 941.142,1986.032 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_666_Conservation-Score_1"/>
<path d="M989.235,1990.383 A2250.000,2250.000 40.000 0,1 997.078,1974.913 L936.990,1944.160 A2317.500,2317.500 0.000 0,0 928.912,1960.095 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_667_Conservation-Score_3" class="Extracellular"/>
<path d="M997.078,1974.913 A2250.000,2250.000 40.000 0,1 1005.040,1959.503 L985.090,1949.098 A2272.500,2272.500 0.000 0,0 977.049,1964.662 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_668_Conservation-Score_0" class="Extracellular"/>
<path d="M1005.040,1959.503 A2250.000,2250.000 40.000 0,1 1013.120,1944.156 L953.513,1912.480 A2317.500,2317.500 0.000 0,0 945.191,1928.288 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_669_Conservation-Score_2"/>
<path d="M1013.120,1944.156 A2250.000,2250.000 40.000 0,1 1021.318,1928.871 L961.958,1896.737 A2317.500,2317.500 0.000 0,0 953.513,1912.480 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_670_Conservation-Score_3"/>
<path d="M1021.318,1928.871 A2250.000,2250.000 40.000 0,1 1029.634,1913.649 L990.227,1891.922 A2295.000,2295.000 0.000 0,0 981.745,1907.448 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_671_Conservation-Score_1" class="Extracellular"/>
<path d="M1029.634,1913.649 A2250.000,2250.000 40.000 0,1 1038.067,1898.492 L979.209,1865.447 A2317.500,2317.500 0.000 0,0 970.523,1881.059 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_672_Conservation-Score_3"/>
<path d="M1038.067,1898.492 A2250.000,2250.000 40.000 0,1 1046.617,1883.401 L988.015,1849.903 A2317.500,2317.500 0.000 0,0 979.209,1865.447 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_673_Conservation-Score_2" class="Extracellular"/>
<path d="M1046.617,1883.401 A2250.000,2250.000 40.000 0,1 1055.282,1868.376 L996.941,1834.427 A2317.500,2317.500 0.000 0,0 988.015,1849.903 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_674_Conservation-Score_2" class="Extracellular"/>
<path d="M1055.282,1868.376 A2250.000,2250.000 40.000 0,1 1064.063,1853.418 L1025.345,1830.487 A2295.000,2295.000 0.000 0,0 1016.388,1845.744 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_675_Conservation-Score_1"/>
<path d="M1064.063,1853.418 A2250.000,2250.000 40.000 0,1 1072.960,1838.529 L880.256,1722.382 A2475.000,2475.000 0.000 0,0 870.470,1738.760 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_676_Conservation-Score_11" class="Extracellular"/>
<path d="M1072.960,1838.529 A2250.000,2250.000 40.000 0,1 1081.970,1823.708 L986.069,1764.894 A2362.500,2362.500 0.000 0,0 976.608,1780.455 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_677_Conservation-Score_5"/>
<path d="M1081.970,1823.708 A2250.000,2250.000 40.000 0,1 1091.095,1808.958 L1033.828,1773.226 A2317.500,2317.500 0.000 0,0 1024.430,1788.419 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_678_Conservation-Score_3"/>
<path d="M1091.095,1808.958 A2250.000,2250.000 40.000 0,1 1100.333,1794.278 L1024.347,1746.049 A2340.000,2340.000 0.000 0,0 1014.739,1761.316 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_679_Conservation-Score_4"/>
<path d="M1100.333,1794.278 A2250.000,2250.000 40.000 0,1 1109.684,1779.669 L920.653,1657.636 A2475.000,2475.000 0.000 0,0 910.367,1673.705 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_680_Conservation-Score_11"/>
<path d="M1109.684,1779.669 A2250.000,2250.000 40.000 0,1 1119.148,1765.134 L1025.105,1703.390 A2362.500,2362.500 0.000 0,0 1015.169,1718.653 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_681_Conservation-Score_5" class="Extracellular"/>
<path d="M1119.148,1765.134 A2250.000,2250.000 40.000 0,1 1128.723,1750.671 L1072.585,1713.191 A2317.500,2317.500 0.000 0,0 1062.722,1728.088 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_682_Conservation-Score_3" class="Extracellular"/>
<path d="M1128.723,1750.671 A2250.000,2250.000 40.000 0,1 1138.409,1736.283 L1045.330,1673.097 A2362.500,2362.500 0.000 0,0 1035.159,1688.205 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_683_Conservation-Score_5"/>
<path d="M1138.409,1736.283 A2250.000,2250.000 40.000 0,1 1148.206,1721.970 L1037.099,1645.288 A2385.000,2385.000 0.000 0,0 1026.714,1660.460 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_684_Conservation-Score_6"/>
<path d="M1148.206,1721.970 A2250.000,2250.000 40.000 0,1 1158.113,1707.733 L1066.019,1643.120 A2362.500,2362.500 0.000 0,0 1055.617,1658.069 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_685_Conservation-Score_5" class="Extracellular"/>
<path d="M1158.113,1707.733 A2250.000,2250.000 40.000 0,1 1168.130,1693.573 L1039.899,1602.123 A2407.500,2407.500 0.000 0,0 1029.181,1617.274 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_686_Conservation-Score_7" class="Extracellular"/>
<path d="M1168.130,1693.573 A2250.000,2250.000 40.000 0,1 1178.255,1679.490 L1087.168,1613.465 A2362.500,2362.500 0.000 0,0 1076.536,1628.251 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_687_Conservation-Score_5" class="Extracellular"/>
<path d="M1178.255,1679.490 A2250.000,2250.000 40.000 0,1 1188.489,1665.486 L1079.798,1585.415 A2385.000,2385.000 0.000 0,0 1068.951,1600.260 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_688_Conservation-Score_6" class="Extracellular"/>
<path d="M1188.489,1665.486 A2250.000,2250.000 40.000 0,1 1198.830,1651.561 L1162.807,1624.592 A2295.000,2295.000 0.000 0,0 1152.259,1638.796 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_689_Conservation-Score_1" class="Extracellular"/>
<path d="M1198.830,1651.561 A2250.000,2250.000 40.000 0,1 1209.279,1637.716 L1155.557,1596.848 A2317.500,2317.500 0.000 0,0 1144.795,1611.108 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_690_Conservation-Score_2" class="Extracellular"/>
<path d="M1209.279,1637.716 A2250.000,2250.000 40.000 0,1 1219.833,1623.953 L1166.428,1582.671 A2317.500,2317.500 0.000 0,0 1155.557,1596.848 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_691_Conservation-Score_2" class="Extracellular"/>
<path d="M1219.833,1623.953 A2250.000,2250.000 40.000 0,1 1230.494,1610.271 L1142.018,1540.784 A2362.500,2362.500 0.000 0,0 1130.825,1555.150 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_692_Conservation-Score_5" class="Extracellular"/>
<path d="M1230.494,1610.271 A2250.000,2250.000 40.000 0,1 1241.259,1596.671 L1153.322,1526.505 A2362.500,2362.500 0.000 0,0 1142.018,1540.784 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_693_Conservation-Score_5" class="Extracellular"/>
<path d="M1241.259,1596.671 A2250.000,2250.000 40.000 0,1 1252.130,1583.155 L1164.736,1512.313 A2362.500,2362.500 0.000 0,0 1153.322,1526.505 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_694_Conservation-Score_5" class="Extracellular"/>
<path d="M1252.130,1583.155 A2250.000,2250.000 40.000 0,1 1263.104,1569.723 L1106.783,1440.999 A2452.500,2452.500 0.000 0,0 1094.821,1455.639 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_695_Conservation-Score_10" class="Extracellular"/>
<path d="M1263.104,1569.723 A2250.000,2250.000 40.000 0,1 1274.181,1556.377 L1170.632,1469.759 A2385.000,2385.000 0.000 0,0 1158.890,1483.907 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_696_Conservation-Score_6"/>
<path d="M1274.181,1556.377 A2250.000,2250.000 40.000 0,1 1285.361,1543.116 L1182.482,1455.702 A2385.000,2385.000 0.000 0,0 1170.632,1469.759 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_697_Conservation-Score_6"/>
<path d="M1285.361,1543.116 A2250.000,2250.000 40.000 0,1 1296.642,1529.941 L1160.374,1412.336 A2430.000,2430.000 0.000 0,0 1148.190,1426.565 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_698_Conservation-Score_8"/>
<path d="M1296.642,1529.941 A2250.000,2250.000 40.000 0,1 1308.025,1516.854 L1223.427,1442.697 A2362.500,2362.500 0.000 0,0 1211.475,1456.438 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_699_Conservation-Score_5" class="Extracellular"/>
<path d="M1308.025,1516.854 A2250.000,2250.000 40.000 0,1 1319.509,1503.855 L1151.460,1354.241 A2475.000,2475.000 0.000 0,0 1138.828,1368.539 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_700_Conservation-Score_11"/>
<path d="M1319.509,1503.855 A2250.000,2250.000 40.000 0,1 1331.092,1490.945 L1281.025,1445.673 A2317.500,2317.500 0.000 0,0 1269.094,1458.971 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_701_Conservation-Score_3" class="Extracellular"/>
<path d="M1331.092,1490.945 A2250.000,2250.000 40.000 0,1 1342.775,1478.125 L1259.914,1402.031 A2362.500,2362.500 0.000 0,0 1247.647,1415.492 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_702_Conservation-Score_5" class="Extracellular"/>
<path d="M1342.775,1478.125 A2250.000,2250.000 40.000 0,1 1354.556,1465.395 L1288.738,1404.010 A2340.000,2340.000 0.000 0,0 1276.486,1417.250 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_703_Conservation-Score_4" class="Extracellular"/>
<path d="M1354.556,1465.395 A2250.000,2250.000 40.000 0,1 1366.435,1452.756 L1203.078,1298.032 A2475.000,2475.000 0.000 0,0 1190.011,1311.934 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_704_Conservation-Score_11"/>
<path d="M1366.435,1452.756 A2250.000,2250.000 40.000 0,1 1378.410,1440.209 L1329.763,1393.415 A2317.500,2317.500 0.000 0,0 1317.428,1406.339 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_705_Conservation-Score_3" class="Extracellular"/>
<path d="M1378.410,1440.209 A2250.000,2250.000 40.000 0,1 1390.483,1427.755 L1358.292,1396.310 A2295.000,2295.000 0.000 0,0 1345.979,1409.013 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_706_Conservation-Score_1"/>
<path d="M1390.483,1427.755 A2250.000,2250.000 40.000 0,1 1402.651,1415.394 L1338.757,1352.010 A2340.000,2340.000 0.000 0,0 1326.102,1364.865 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_707_Conservation-Score_4" class="Extracellular"/>
<path d="M1402.651,1415.394 A2250.000,2250.000 40.000 0,1 1414.913,1403.128 L1288.107,1275.378 A2430.000,2430.000 0.000 0,0 1274.863,1288.626 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_708_Conservation-Score_9"/>
<path d="M1414.913,1403.128 A2250.000,2250.000 40.000 0,1 1427.270,1390.956 L1395.816,1358.775 A2295.000,2295.000 0.000 0,0 1383.212,1371.190 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_709_Conservation-Score_1" class="Extracellular"/>
<path d="M1427.270,1390.956 A2250.000,2250.000 40.000 0,1 1439.721,1378.880 L1392.913,1330.247 A2317.500,2317.500 0.000 0,0 1380.089,1342.685 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_710_Conservation-Score_3"/>
<path d="M1439.721,1378.880 A2250.000,2250.000 40.000 0,1 1452.264,1366.901 L1436.787,1350.570 A2272.500,2272.500 0.000 0,0 1424.118,1362.669 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_711_Conservation-Score_0" class="Extracellular"/>
<path d="M1452.264,1366.901 A2250.000,2250.000 40.000 0,1 1464.899,1355.018 L1434.197,1322.118 A2295.000,2295.000 0.000 0,0 1421.309,1334.239 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_712_Conservation-Score_1"/>
<path d="M1464.899,1355.018 A2250.000,2250.000 40.000 0,1 1477.626,1343.233 L1431.954,1293.530 A2317.500,2317.500 0.000 0,0 1418.846,1305.669 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_713_Conservation-Score_2" class="Extracellular"/>
<path d="M1477.626,1343.233 A2250.000,2250.000 40.000 0,1 1490.442,1331.547 L1414.965,1248.124 A2362.500,2362.500 0.000 0,0 1401.507,1260.395 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_714_Conservation-Score_5" class="Extracellular"/>
<path d="M1490.442,1331.547 A2250.000,2250.000 40.000 0,1 1503.349,1319.960 L1383.617,1185.556 A2430.000,2430.000 0.000 0,0 1369.678,1198.071 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_715_Conservation-Score_8" class="Extracellular"/>
<path d="M1503.349,1319.960 A2250.000,2250.000 40.000 0,1 1516.345,1308.472 L1456.998,1240.811 A2340.000,2340.000 0.000 0,0 1443.483,1252.758 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_716_Conservation-Score_4"/>
<path d="M1516.345,1308.472 A2250.000,2250.000 40.000 0,1 1529.428,1297.085 L1455.900,1211.940 A2362.500,2362.500 0.000 0,0 1442.162,1223.896 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_717_Conservation-Score_5"/>
<path d="M1529.428,1297.085 A2250.000,2250.000 40.000 0,1 1542.599,1285.800 L1440.581,1165.806 A2407.500,2407.500 0.000 0,0 1426.488,1177.881 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_718_Conservation-Score_7"/>
<path d="M1542.599,1285.800 A2250.000,2250.000 40.000 0,1 1555.857,1274.616 L1469.208,1171.093 A2385.000,2385.000 0.000 0,0 1455.155,1182.948 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_719_Conservation-Score_6" class="Extracellular"/>
<path d="M1555.857,1274.616 A2250.000,2250.000 40.000 0,1 1569.200,1263.534 L1454.736,1124.617 A2430.000,2430.000 0.000 0,0 1440.326,1136.585 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_720_Conservation-Score_8" class="Extracellular"/>
<path d="M1569.200,1263.534 A2250.000,2250.000 40.000 0,1 1582.629,1252.556 L1511.760,1165.184 A2362.500,2362.500 0.000 0,0 1497.660,1176.711 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_721_Conservation-Score_5" class="Extracellular"/>
<path d="M1582.629,1252.556 A2250.000,2250.000 40.000 0,1 1596.142,1241.682 L1539.987,1171.349 A2340.000,2340.000 0.000 0,0 1525.934,1182.659 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_722_Conservation-Score_4"/>
<path d="M1596.142,1241.682 A2250.000,2250.000 40.000 0,1 1609.738,1230.912 L1498.517,1089.385 A2430.000,2430.000 0.000 0,0 1483.833,1101.017 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_723_Conservation-Score_9" class="Extracellular"/>
<path d="M1609.738,1230.912 A2250.000,2250.000 40.000 0,1 1623.417,1220.248 L1568.353,1149.058 A2340.000,2340.000 0.000 0,0 1554.127,1160.149 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_724_Conservation-Score_4"/>
<path d="M1623.417,1220.248 A2250.000,2250.000 40.000 0,1 1637.177,1209.689 L1528.151,1066.464 A2430.000,2430.000 0.000 0,0 1513.290,1077.868 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_725_Conservation-Score_8" class="Extracellular"/>
<path d="M1637.177,1209.689 A2250.000,2250.000 40.000 0,1 1651.019,1199.236 L1637.529,1181.229 A2272.500,2272.500 0.000 0,0 1623.549,1191.786 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_726_Conservation-Score_0" class="Extracellular"/>
<path d="M1651.019,1199.236 A2250.000,2250.000 40.000 0,1 1664.941,1188.891 L1638.239,1152.669 A2295.000,2295.000 0.000 0,0 1624.039,1163.221 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_727_Conservation-Score_1" class="Extracellular"/>
<path d="M1664.941,1188.891 A2250.000,2250.000 40.000 0,1 1678.942,1178.653 L1652.520,1142.226 A2295.000,2295.000 0.000 0,0 1638.239,1152.669 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_728_Conservation-Score_1" class="Extracellular"/>
<path d="M1678.942,1178.653 A2250.000,2250.000 40.000 0,1 1693.021,1168.523 L1627.672,1076.950 A2362.500,2362.500 0.000 0,0 1612.889,1087.586 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_729_Conservation-Score_5" class="Extracellular"/>
<path d="M1693.021,1168.523 A2250.000,2250.000 40.000 0,1 1707.178,1158.503 L1616.681,1029.598 A2407.500,2407.500 0.000 0,0 1601.533,1040.320 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_730_Conservation-Score_7" class="Extracellular"/>
<path d="M1707.178,1158.503 A2250.000,2250.000 40.000 0,1 1721.413,1148.591 L1593.554,963.450 A2475.000,2475.000 0.000 0,0 1577.896,974.353 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_731_Conservation-Score_11"/>
<path d="M1721.413,1148.591 A2250.000,2250.000 40.000 0,1 1735.723,1138.790 L1697.794,1082.954 A2317.500,2317.500 0.000 0,0 1683.055,1093.049 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_732_Conservation-Score_3"/>
<path d="M1735.723,1138.790 A2250.000,2250.000 40.000 0,1 1750.108,1129.099 L1712.611,1072.972 A2317.500,2317.500 0.000 0,0 1697.794,1082.954 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_733_Conservation-Score_2"/>
<path d="M1750.108,1129.099 A2250.000,2250.000 40.000 0,1 1764.567,1119.520 L1727.504,1063.105 A2317.500,2317.500 0.000 0,0 1712.611,1072.972 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_734_Conservation-Score_2"/>
<path d="M1764.567,1119.520 A2250.000,2250.000 40.000 0,1 1779.100,1110.052 L1766.891,1091.152 A2272.500,2272.500 0.000 0,0 1752.213,1100.715 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_735_Conservation-Score_0"/>
<path d="M1779.100,1110.052 A2250.000,2250.000 40.000 0,1 1793.706,1100.696 L1769.580,1062.710 A2295.000,2295.000 0.000 0,0 1754.682,1072.253 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_736_Conservation-Score_1"/>
<path d="M1793.706,1100.696 A2250.000,2250.000 40.000 0,1 1808.383,1091.454 L1784.550,1053.283 A2295.000,2295.000 0.000 0,0 1769.580,1062.710 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_737_Conservation-Score_1"/>
<path d="M1808.383,1091.454 A2250.000,2250.000 40.000 0,1 1823.131,1082.325 L1799.593,1043.971 A2295.000,2295.000 0.000 0,0 1784.550,1053.283 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" id="Residue_738_Conservation-Score_1" class="Extracellular"/>
<path d="M1823.131,1082.325 A2250.000,2250.000 40.000 0,1 1837.949,1073.309 L1803.087,1015.509 A2317.500,2317.500 0.000 0,0 1787.825,1024.794 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_739_Conservation-Score_3"/>
<path d="M1837.949,1073.309 A2250.000,2250.000 40.000 0,1 1852.835,1064.409 L1818.421,1006.341 A2317.500,2317.500 0.000 0,0 1803.087,1015.509 Z" style="stroke-width:3.0;stroke:rgb(158,202,225);stroke-linecap:round;fill:rgb(107,174,214);" class="Extracellular" id="Residue_740_Conservation-Score_2"/>
<path d="M1852.835,1064.409 A2250.000,2250.000 40.000 0,1 1867.791,1055.623 L1833.824,997.292 A2317.500,2317.500 0.000 0,0 1818.421,1006.341 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_741_Conservation-Score_2" class="Transmembrane"/>
<path d="M1867.791,1055.623 A2250.000,2250.000 40.000 0,1 1882.813,1046.953 L1849.297,988.361 A2317.500,2317.500 0.000 0,0 1833.824,997.292 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_742_Conservation-Score_3"/>
<path d="M1882.813,1046.953 A2250.000,2250.000 40.000 0,1 1897.902,1038.399 L1864.839,979.551 A2317.500,2317.500 0.000 0,0 1849.297,988.361 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_743_Conservation-Score_2" class="Transmembrane"/>
<path d="M1897.902,1038.399 A2250.000,2250.000 40.000 0,1 1913.056,1029.961 L1880.448,970.860 A2317.500,2317.500 0.000 0,0 1864.839,979.551 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_744_Conservation-Score_2"/>
<path d="M1913.056,1029.961 A2250.000,2250.000 40.000 0,1 1928.275,1021.641 L1896.123,962.290 A2317.500,2317.500 0.000 0,0 1880.448,970.860 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_745_Conservation-Score_2"/>
<path d="M1928.275,1021.641 A2250.000,2250.000 40.000 0,1 1943.557,1013.438 L1911.864,953.841 A2317.500,2317.500 0.000 0,0 1896.123,962.290 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_746_Conservation-Score_2" class="Transmembrane"/>
<path d="M1943.557,1013.438 A2250.000,2250.000 40.000 0,1 1958.903,1005.353 L1927.670,945.514 A2317.500,2317.500 0.000 0,0 1911.864,953.841 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_747_Conservation-Score_3"/>
<path d="M1958.903,1005.353 A2250.000,2250.000 40.000 0,1 1974.310,997.387 L1943.539,937.308 A2317.500,2317.500 0.000 0,0 1927.670,945.514 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_748_Conservation-Score_3"/>
<path d="M1974.310,997.387 A2250.000,2250.000 40.000 0,1 1989.778,989.539 L1959.471,929.226 A2317.500,2317.500 0.000 0,0 1943.539,937.308 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_749_Conservation-Score_3"/>
<path d="M1989.778,989.539 A2250.000,2250.000 40.000 0,1 2005.306,981.812 L1985.412,941.448 A2295.000,2295.000 0.000 0,0 1969.574,949.330 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_750_Conservation-Score_1" class="Transmembrane"/>
<path d="M2005.306,981.812 A2250.000,2250.000 40.000 0,1 2020.893,974.204 L1991.520,913.430 A2317.500,2317.500 0.000 0,0 1975.465,921.266 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_751_Conservation-Score_3"/>
<path d="M2020.893,974.204 A2250.000,2250.000 40.000 0,1 2036.539,966.716 L2017.270,926.051 A2295.000,2295.000 0.000 0,0 2001.311,933.688 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_752_Conservation-Score_1" class="Transmembrane"/>
<path d="M2036.539,966.716 A2250.000,2250.000 40.000 0,1 2052.242,959.350 L2023.809,898.130 A2317.500,2317.500 0.000 0,0 2007.635,905.718 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_753_Conservation-Score_2"/>
<path d="M2052.242,959.350 A2250.000,2250.000 40.000 0,1 2068.001,952.104 L2040.041,890.667 A2317.500,2317.500 0.000 0,0 2023.809,898.130 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_754_Conservation-Score_3"/>
<path d="M2068.001,952.104 A2250.000,2250.000 40.000 0,1 2083.815,944.980 L2056.330,883.330 A2317.500,2317.500 0.000 0,0 2040.041,890.667 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_755_Conservation-Score_2"/>
<path d="M2083.815,944.980 A2250.000,2250.000 40.000 0,1 2099.684,937.979 L2072.675,876.118 A2317.500,2317.500 0.000 0,0 2056.330,883.330 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_756_Conservation-Score_3" class="Transmembrane"/>
<path d="M2099.684,937.979 A2250.000,2250.000 40.000 0,1 2115.606,931.100 L2089.075,869.033 A2317.500,2317.500 0.000 0,0 2072.675,876.118 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_757_Conservation-Score_2" class="Transmembrane"/>
<path d="M2115.606,931.100 A2250.000,2250.000 40.000 0,1 2131.581,924.344 L2105.529,862.074 A2317.500,2317.500 0.000 0,0 2089.075,869.033 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" id="Residue_758_Conservation-Score_2" class="Transmembrane"/>
<path d="M2131.581,924.344 A2250.000,2250.000 40.000 0,1 2147.608,917.711 L2122.036,855.242 A2317.500,2317.500 0.000 0,0 2105.529,862.074 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_759_Conservation-Score_2"/>
<path d="M2147.608,917.711 A2250.000,2250.000 40.000 0,1 2163.685,911.202 L2138.596,848.538 A2317.500,2317.500 0.000 0,0 2122.036,855.242 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_760_Conservation-Score_2"/>
<path d="M2163.685,911.202 A2250.000,2250.000 40.000 0,1 2179.812,904.817 L2155.206,841.962 A2317.500,2317.500 0.000 0,0 2138.596,848.538 Z" style="stroke-width:3.0;stroke:rgb(253,174,107);stroke-linecap:round;fill:rgb(253,141,60);" class="Transmembrane" id="Residue_761_Conservation-Score_2"/>
<path d="M2179.812,904.817 A2250.000,2250.000 40.000 0,1 2195.988,898.557 L2179.907,856.528 A2295.000,2295.000 0.000 0,0 2163.408,862.913 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_762_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2195.988,898.557 A2250.000,2250.000 40.000 0,1 2212.211,892.421 L2188.577,829.194 A2317.500,2317.500 0.000 0,0 2171.867,835.513 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_763_Conservation-Score_2"/>
<path d="M2212.211,892.421 A2250.000,2250.000 40.000 0,1 2228.481,886.411 L2205.336,823.003 A2317.500,2317.500 0.000 0,0 2188.577,829.194 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_764_Conservation-Score_3" class="Cytoplasmic"/>
<path d="M2228.481,886.411 A2250.000,2250.000 40.000 0,1 2244.797,880.526 L2222.141,816.942 A2317.500,2317.500 0.000 0,0 2205.336,823.003 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_765_Conservation-Score_2"/>
<path d="M2244.797,880.526 A2250.000,2250.000 40.000 0,1 2261.158,874.768 L2238.993,811.011 A2317.500,2317.500 0.000 0,0 2222.141,816.942 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_766_Conservation-Score_3"/>
<path d="M2261.158,874.768 A2250.000,2250.000 40.000 0,1 2277.563,869.135 L2263.114,826.518 A2295.000,2295.000 0.000 0,0 2246.382,832.263 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_767_Conservation-Score_1"/>
<path d="M2277.563,869.135 A2250.000,2250.000 40.000 0,1 2294.011,863.629 L2272.831,799.538 A2317.500,2317.500 0.000 0,0 2255.890,805.209 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_768_Conservation-Score_3" class="Cytoplasmic"/>
<path d="M2294.011,863.629 A2250.000,2250.000 40.000 0,1 2310.501,858.251 L2289.816,793.998 A2317.500,2317.500 0.000 0,0 2272.831,799.538 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_769_Conservation-Score_3" class="Cytoplasmic"/>
<path d="M2310.501,858.251 A2250.000,2250.000 40.000 0,1 2327.031,852.999 L2300.113,767.119 A2340.000,2340.000 0.000 0,0 2282.921,772.581 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_770_Conservation-Score_4" class="Cytoplasmic"/>
<path d="M2327.031,852.999 A2250.000,2250.000 40.000 0,1 2343.602,847.875 L2330.474,804.833 A2295.000,2295.000 0.000 0,0 2313.572,810.059 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_771_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2343.602,847.875 A2250.000,2250.000 40.000 0,1 2360.212,842.879 L2341.018,778.165 A2317.500,2317.500 0.000 0,0 2323.910,783.311 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_772_Conservation-Score_2"/>
<path d="M2360.212,842.879 A2250.000,2250.000 40.000 0,1 2376.860,838.011 L2364.397,794.771 A2295.000,2295.000 0.000 0,0 2347.416,799.737 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_773_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2376.860,838.011 A2250.000,2250.000 40.000 0,1 2393.544,833.272 L2375.351,768.270 A2317.500,2317.500 0.000 0,0 2358.165,773.151 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_774_Conservation-Score_2"/>
<path d="M2393.544,833.272 A2250.000,2250.000 40.000 0,1 2410.265,828.661 L2404.368,806.948 A2272.500,2272.500 0.000 0,0 2387.480,811.604 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_775_Conservation-Score_0" class="Cytoplasmic"/>
<path d="M2410.265,828.661 A2250.000,2250.000 40.000 0,1 2427.021,824.179 L2415.562,780.663 A2295.000,2295.000 0.000 0,0 2398.471,785.234 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_776_Conservation-Score_1"/>
<path d="M2427.021,824.179 A2250.000,2250.000 40.000 0,1 2443.811,819.827 L2438.249,798.025 A2272.500,2272.500 0.000 0,0 2421.291,802.421 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_777_Conservation-Score_0" class="Cytoplasmic"/>
<path d="M2443.811,819.827 A2250.000,2250.000 40.000 0,1 2460.634,815.604 L2444.453,750.072 A2317.500,2317.500 0.000 0,0 2427.125,754.422 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_778_Conservation-Score_3"/>
<path d="M2460.634,815.604 A2250.000,2250.000 40.000 0,1 2477.489,811.511 L2461.814,745.857 A2317.500,2317.500 0.000 0,0 2444.453,750.072 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_779_Conservation-Score_2"/>
<path d="M2477.489,811.511 A2250.000,2250.000 40.000 0,1 2494.375,807.549 L2479.206,741.775 A2317.500,2317.500 0.000 0,0 2461.814,745.857 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_780_Conservation-Score_2" class="Cytoplasmic"/>
<path d="M2494.375,807.549 A2250.000,2250.000 40.000 0,1 2511.291,803.716 L2496.630,737.827 A2317.500,2317.500 0.000 0,0 2479.206,741.775 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_781_Conservation-Score_3" class="Cytoplasmic"/>
<path d="M2511.291,803.716 A2250.000,2250.000 40.000 0,1 2528.236,800.014 L2518.801,756.014 A2295.000,2295.000 0.000 0,0 2501.517,759.790 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_782_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2528.236,800.014 A2250.000,2250.000 40.000 0,1 2545.210,796.443 L2531.566,730.336 A2317.500,2317.500 0.000 0,0 2514.083,734.014 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_783_Conservation-Score_3"/>
<path d="M2545.210,796.443 A2250.000,2250.000 40.000 0,1 2562.210,793.002 L2553.454,748.862 A2295.000,2295.000 0.000 0,0 2536.114,752.371 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_784_Conservation-Score_1"/>
<path d="M2562.210,793.002 A2250.000,2250.000 40.000 0,1 2579.236,789.693 L2562.405,701.281 A2340.000,2340.000 0.000 0,0 2544.698,704.722 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_785_Conservation-Score_4"/>
<path d="M2579.236,789.693 A2250.000,2250.000 40.000 0,1 2596.287,786.515 L2588.213,742.245 A2295.000,2295.000 0.000 0,0 2570.821,745.487 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_786_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2596.287,786.515 A2250.000,2250.000 40.000 0,1 2613.362,783.469 L2609.496,761.303 A2272.500,2272.500 0.000 0,0 2592.250,764.380 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_787_Conservation-Score_0"/>
<path d="M2613.362,783.469 A2250.000,2250.000 40.000 0,1 2630.461,780.554 L2619.374,713.971 A2317.500,2317.500 0.000 0,0 2601.763,716.973 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_788_Conservation-Score_2" class="Cytoplasmic"/>
<path d="M2630.461,780.554 A2250.000,2250.000 40.000 0,1 2647.581,777.771 L2644.057,755.549 A2272.500,2272.500 0.000 0,0 2626.765,758.360 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_789_Conservation-Score_0" class="Cytoplasmic"/>
<path d="M2647.581,777.771 A2250.000,2250.000 40.000 0,1 2664.722,775.121 L2658.016,730.623 A2295.000,2295.000 0.000 0,0 2640.532,733.327 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_790_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2664.722,775.121 A2250.000,2250.000 40.000 0,1 2681.883,772.602 L2672.339,705.780 A2317.500,2317.500 0.000 0,0 2654.664,708.374 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_791_Conservation-Score_2"/>
<path d="M2681.883,772.602 A2250.000,2250.000 40.000 0,1 2699.063,770.216 L2690.035,703.322 A2317.500,2317.500 0.000 0,0 2672.339,705.780 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_792_Conservation-Score_2" class="Cytoplasmic"/>
<path d="M2699.063,770.216 A2250.000,2250.000 40.000 0,1 2716.261,767.962 L2713.423,745.642 A2272.500,2272.500 0.000 0,0 2696.053,747.918 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_793_Conservation-Score_0"/>
<path d="M2716.261,767.962 A2250.000,2250.000 40.000 0,1 2733.475,765.841 L2725.480,698.817 A2317.500,2317.500 0.000 0,0 2707.748,701.001 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_794_Conservation-Score_2"/>
<path d="M2733.475,765.841 A2250.000,2250.000 40.000 0,1 2750.706,763.853 L2745.720,719.130 A2295.000,2295.000 0.000 0,0 2728.145,721.158 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_795_Conservation-Score_1"/>
<path d="M2750.706,763.853 A2250.000,2250.000 40.000 0,1 2767.951,761.998 L2763.310,717.238 A2295.000,2295.000 0.000 0,0 2745.720,719.130 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_796_Conservation-Score_1" class="Cytoplasmic"/>
<path d="M2767.951,761.998 A2250.000,2250.000 40.000 0,1 2785.210,760.276 L2780.915,715.481 A2295.000,2295.000 0.000 0,0 2763.310,717.238 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_797_Conservation-Score_1"/>
<path d="M2785.210,760.276 A2250.000,2250.000 40.000 0,1 2802.482,758.686 L2800.507,736.273 A2272.500,2272.500 0.000 0,0 2783.062,737.878 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_798_Conservation-Score_0" class="Cytoplasmic"/>
<path d="M2802.482,758.686 A2250.000,2250.000 40.000 0,1 2819.766,757.230 L2814.359,689.947 A2317.500,2317.500 0.000 0,0 2796.557,691.447 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_799_Conservation-Score_2" class="Cytoplasmic"/>
<path d="M2819.766,757.230 A2250.000,2250.000 40.000 0,1 2837.060,755.908 L2830.543,666.144 A2340.000,2340.000 0.000 0,0 2812.556,667.520 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_800_Conservation-Score_4" class="Cytoplasmic"/>
<path d="M2837.060,755.908 A2250.000,2250.000 40.000 0,1 2854.364,754.718 L2849.995,687.360 A2317.500,2317.500 0.000 0,0 2832.172,688.585 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_801_Conservation-Score_2"/>
<path d="M2854.364,754.718 A2250.000,2250.000 40.000 0,1 2871.677,753.662 L2870.394,731.199 A2272.500,2272.500 0.000 0,0 2852.908,732.265 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_802_Conservation-Score_0"/>
<path d="M2871.677,753.662 A2250.000,2250.000 40.000 0,1 2888.997,752.740 L2885.667,685.322 A2317.500,2317.500 0.000 0,0 2867.827,686.272 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" id="Residue_803_Conservation-Score_3" class="Cytoplasmic"/>
<path d="M2888.997,752.740 A2250.000,2250.000 40.000 0,1 2906.324,751.951 L2903.514,684.509 A2317.500,2317.500 0.000 0,0 2885.667,685.322 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_804_Conservation-Score_3"/>
<path d="M2906.324,751.951 A2250.000,2250.000 40.000 0,1 2923.656,751.296 L2922.130,706.321 A2295.000,2295.000 0.000 0,0 2904.451,706.990 Z" style="stroke-width:3.0;stroke:rgb(161,217,155);stroke-linecap:round;fill:rgb(116,196,118);" class="Cytoplasmic" id="Residue_805_Conservation-Score_1"/>
</g>
<g id="plot1">
<g id="plot1-axis">
</g>
<text x="3188.6" y="813.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(364.9,3188.6,813.5)" class="sequence" id="seq_Tryptophan_6">W</text>
<text x="3858.5" y="1023.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(383.5,3858.5,1023.8)" class="sequence" id="seq_Tryptophan_48">W</text>
<text x="4167.9" y="1184.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(392.8,4167.9,1184.6)" class="sequence" id="seq_Tryptophan_69">W</text>
<text x="5072.1" y="2416.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(434.3,5072.1,2416.5)" id="seq_Tryptophan_163" class="sequence">W</text>
<text x="5086.6" y="2447.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(435.2,5086.6,2447.0)" id="seq_Tryptophan_165" class="sequence">W</text>
<text x="5114.4" y="2491.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(436.5,5114.4,2491.7)" class="sequence" id="seq_Tryptophan_168">W</text>
<text x="5184.4" y="3074.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-88.1,5184.4,3074.0)" id="seq_Tryptophan_203" class="sequence">W</text>
<text x="4859.1" y="4160.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-58.0,4859.1,4160.6)" class="sequence" id="seq_Tryptophan_271">W</text>
<text x="4813.3" y="4211.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-56.3,4813.3,4211.3)" class="sequence" id="seq_Tryptophan_275">W</text>
<text x="4527.4" y="4563.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-44.3,4527.4,4563.4)" class="sequence" id="seq_Tryptophan_302">W</text>
<text x="4182.8" y="4832.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-32.8,4182.8,4832.0)" id="seq_Tryptophan_328" class="sequence">W</text>
<text x="3853.3" y="4986.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-23.3,3853.3,4986.1)" class="sequence" id="seq_Tryptophan_349">W</text>
<text x="2067.4" y="4998.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(25.0,2067.4,4998.8)" class="sequence" id="seq_Tryptophan_459">W</text>
<text x="2046.3" y="4964.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(25.9,2046.3,4964.4)" class="sequence" id="seq_Tryptophan_461">W</text>
<text x="1853.9" y="4892.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(31.2,1853.9,4892.7)" class="sequence" id="seq_Tryptophan_473">W</text>
<text x="1810.8" y="4833.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(33.0,1810.8,4833.8)" class="sequence" id="seq_Tryptophan_477">W</text>
<text x="1778.0" y="4853.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(33.4,1778.0,4853.0)" class="sequence" id="seq_Tryptophan_478">W</text>
<text x="881.9" y="3677.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(72.3,881.9,3677.1)" class="sequence" id="seq_Tryptophan_566">W</text>
<text x="787.1" y="3207.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(84.6,787.1,3207.6)" id="seq_Tryptophan_594" class="sequence">W</text>
<text x="814.4" y="3002.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(89.9,814.4,3002.3)" id="seq_Tryptophan_606" class="sequence">W</text>
<text x="866.7" y="2924.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-88.0,866.7,2924.4)" id="seq_Tryptophan_610" class="sequence">W</text>
<text x="898.5" y="2524.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-77.3,898.5,2524.5)" class="sequence" id="seq_Tryptophan_635">W</text>
<text x="1918.0" y="1125.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-30.0,1918.0,1125.2)" id="seq_Tryptophan_742" class="sequence">W</text>
<text x="3101.3" y="867.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(362.7,3101.3,867.8)" id="seq_Methionine_1" class="sequence">M</text>
<text x="4081.2" y="1101.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(389.7,4081.2,1101.7)" id="seq_Methionine_62" class="sequence">M</text>
<text x="4339.7" y="1338.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(398.9,4339.7,1338.1)" class="sequence" id="seq_Methionine_82">M</text>
<text x="4802.3" y="1811.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(416.6,4802.3,1811.9)" id="seq_Methionine_123" class="sequence">M</text>
<text x="5026.4" y="2238.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(429.4,5026.4,2238.9)" class="sequence" id="seq_Methionine_152">M</text>
<text x="5149.9" y="2857.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(446.2,5149.9,2857.2)" id="seq_Methionine_190" class="sequence">M</text>
<text x="5017.2" y="3825.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-67.7,5017.2,3825.6)" class="sequence" id="seq_Methionine_249">M</text>
<text x="4836.1" y="4140.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-58.1,4836.1,4140.9)" id="seq_Methionine_270" class="sequence">M</text>
<text x="4586.5" y="4503.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-46.5,4586.5,4503.4)" id="seq_Methionine_297" class="sequence">M</text>
<text x="4231.7" y="4776.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-34.7,4231.7,4776.4)" id="seq_Methionine_323" class="sequence">M</text>
<text x="4126.3" y="4868.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-31.1,4126.3,4868.4)" class="sequence" id="seq_Methionine_332">M</text>
<text x="3702.6" y="5073.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-18.7,3702.6,5073.9)" id="seq_Methionine_360" class="sequence">M</text>
<text x="3611.5" y="5123.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-16.1,3611.5,5123.4)" class="sequence" id="seq_Methionine_366">M</text>
<text x="3440.5" y="5136.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-11.6,3440.5,5136.7)" id="seq_Methionine_376" class="sequence">M</text>
<text x="3325.3" y="5162.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-8.6,3325.3,5162.3)" class="sequence" id="seq_Methionine_383">M</text>
<text x="2905.8" y="5169.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(2.5,2905.8,5169.6)" class="sequence" id="seq_Methionine_408">M</text>
<text x="2135.7" y="4981.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(23.6,2135.7,4981.3)" class="sequence" id="seq_Methionine_455">M</text>
<text x="2016.1" y="4987.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(26.3,2016.1,4987.5)" id="seq_Methionine_462" class="sequence">M</text>
<text x="1855.8" y="4834.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(32.0,1855.8,4834.0)" id="seq_Methionine_474" class="sequence">M</text>
<text x="1771.0" y="4802.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(34.3,1771.0,4802.5)" id="seq_Methionine_480" class="sequence">M</text>
<text x="969.4" y="3795.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(68.6,969.4,3795.0)" class="sequence" id="seq_Methionine_557">M</text>
<text x="883.0" y="3437.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(78.3,883.0,3437.0)" class="sequence" id="seq_Methionine_579">M</text>
<text x="895.2" y="2437.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-75.0,895.2,2437.7)" id="seq_Methionine_640" class="sequence">M</text>
<text x="995.8" y="2265.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-69.9,995.8,2265.1)" id="seq_Methionine_651" class="sequence">M</text>
<text x="1066.1" y="2096.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-65.0,1066.1,2096.2)" class="sequence" id="seq_Methionine_662">M</text>
<text x="1444.3" y="1492.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-45.9,1444.3,1492.0)" id="seq_Methionine_706" class="sequence">M</text>
<text x="2038.2" y="1067.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-26.5,2038.2,1067.4)" class="sequence" id="seq_Methionine_750">M</text>
<text x="3387.6" y="852.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(370.2,3387.6,852.0)" class="sequence" id="seq_Glutamine_18">Q</text>
<text x="3487.0" y="870.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(372.9,3487.0,870.3)" class="sequence" id="seq_Glutamine_24">Q</text>
<text x="3772.1" y="1009.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(381.2,3772.1,1009.9)" class="sequence" id="seq_Glutamine_42">Q</text>
<text x="4040.0" y="1135.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(389.2,4040.0,1135.8)" id="seq_Glutamine_60" class="sequence">Q</text>
<text x="4261.8" y="1253.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(395.8,4261.8,1253.5)" id="seq_Glutamine_76" class="sequence">Q</text>
<text x="4341.7" y="1286.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(398.1,4341.7,1286.1)" id="seq_Glutamine_81" class="sequence">Q</text>
<text x="4405.5" y="1340.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(400.3,4405.5,1340.6)" class="sequence" id="seq_Glutamine_86">Q</text>
<text x="4436.9" y="1381.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(401.6,4436.9,1381.0)" id="seq_Glutamine_89" class="sequence">Q</text>
<text x="4513.7" y="1469.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(404.7,4513.7,1469.4)" class="sequence" id="seq_Glutamine_96">Q</text>
<text x="4537.1" y="1492.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(405.6,4537.1,1492.9)" class="sequence" id="seq_Glutamine_98">Q</text>
<text x="4571.5" y="1528.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(406.9,4571.5,1528.9)" id="seq_Glutamine_101" class="sequence">Q</text>
<text x="4601.9" y="1523.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(407.3,4601.9,1523.4)" class="sequence" id="seq_Glutamine_102">Q</text>
<text x="4933.0" y="2043.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(423.7,4933.0,2043.5)" id="seq_Glutamine_139" class="sequence">Q</text>
<text x="5123.0" y="2609.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(439.6,5123.0,2609.4)" id="seq_Glutamine_175" class="sequence">Q</text>
<text x="5158.1" y="3376.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-80.1,5158.1,3376.3)" class="sequence" id="seq_Glutamine_221">Q</text>
<text x="4716.2" y="4391.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-51.0,4716.2,4391.8)" class="sequence" id="seq_Glutamine_287">Q</text>
<text x="4572.6" y="4560.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-45.2,4572.6,4560.8)" class="sequence" id="seq_Glutamine_300">Q</text>
<text x="4511.3" y="4620.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-43.0,4511.3,4620.2)" id="seq_Glutamine_305" class="sequence">Q</text>
<text x="4205.2" y="4800.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-33.8,4205.2,4800.5)" class="sequence" id="seq_Glutamine_325">Q</text>
<text x="4013.2" y="4942.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-27.5,4013.2,4942.3)" class="sequence" id="seq_Glutamine_340">Q</text>
<text x="3373.5" y="5144.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-9.9,3373.5,5144.4)" id="seq_Glutamine_380" class="sequence">Q</text>
<text x="3242.2" y="5177.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-6.3,3242.2,5177.2)" class="sequence" id="seq_Glutamine_388">Q</text>
<text x="2554.5" y="5139.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(11.8,2554.5,5139.8)" class="sequence" id="seq_Glutamine_429">Q</text>
<text x="2335.7" y="5106.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(17.5,2335.7,5106.4)" id="seq_Glutamine_442" class="sequence">Q</text>
<text x="1879.3" y="4883.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(30.8,1879.3,4883.4)" class="sequence" id="seq_Glutamine_472">Q</text>
<text x="1239.9" y="4334.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(52.8,1239.9,4334.2)" id="seq_Glutamine_522" class="sequence">Q</text>
<text x="1238.0" y="4293.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(53.7,1238.0,4293.3)" class="sequence" id="seq_Glutamine_524">Q</text>
<text x="1218.3" y="4266.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(54.6,1218.3,4266.0)" class="sequence" id="seq_Glutamine_526">Q</text>
<text x="1152.4" y="4208.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(56.8,1152.4,4208.4)" class="sequence" id="seq_Glutamine_531">Q</text>
<text x="1012.8" y="3863.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(66.5,1012.8,3863.3)" id="seq_Glutamine_552" class="sequence">Q</text>
<text x="836.8" y="3121.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(86.8,836.8,3121.6)" id="seq_Glutamine_598" class="sequence">Q</text>
<text x="846.6" y="2836.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-85.6,846.6,2836.0)" id="seq_Glutamine_616" class="sequence">Q</text>
<text x="954.5" y="2227.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-69.3,954.5,2227.1)" class="sequence" id="seq_Glutamine_653">Q</text>
<text x="1009.7" y="2104.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-65.8,1009.7,2104.2)" class="sequence" id="seq_Glutamine_661">Q</text>
<text x="1734.1" y="1268.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-36.2,1734.1,1268.8)" class="sequence" id="seq_Glutamine_728">Q</text>
<text x="1860.4" y="1195.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-32.3,1860.4,1195.0)" id="seq_Glutamine_736" class="sequence">Q</text>
<text x="2769.6" y="858.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-6.1,2769.6,858.7)" class="sequence" id="seq_Glutamine_796">Q</text>
<text x="2868.6" y="845.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-3.5,2868.6,845.4)" class="sequence" id="seq_Glutamine_802">Q</text>
<text x="3581.4" y="907.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(375.5,3581.4,907.6)" class="sequence" id="seq_Aspartic-Acid_30">D</text>
<text x="3703.7" y="963.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(379.1,3703.7,963.5)" class="sequence" id="seq_Aspartic-Acid_38">D</text>
<text x="4139.8" y="1166.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(391.9,4139.8,1166.8)" id="seq_Aspartic-Acid_67" class="sequence">D</text>
<text x="4673.6" y="1674.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(411.6,4673.6,1674.9)" class="sequence" id="seq_Aspartic-Acid_111">D</text>
<text x="4910.3" y="1999.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(422.3,4910.3,1999.1)" id="seq_Aspartic-Acid_136" class="sequence">D</text>
<text x="5061.9" y="2315.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(431.6,5061.9,2315.1)" id="seq_Aspartic-Acid_157" class="sequence">D</text>
<text x="5154.6" y="2989.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(449.7,5154.6,2989.9)" id="seq_Aspartic-Acid_198" class="sequence">D</text>
<text x="5185.3" y="3040.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-88.9,5185.3,3040.3)" class="sequence" id="seq_Aspartic-Acid_201">D</text>
<text x="5204.1" y="3125.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-86.7,5204.1,3125.8)" id="seq_Aspartic-Acid_206" class="sequence">D</text>
<text x="5147.0" y="3251.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-83.3,5147.0,3251.4)" class="sequence" id="seq_Aspartic-Acid_213">D</text>
<text x="5166.0" y="3292.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-82.3,5166.0,3292.2)" id="seq_Aspartic-Acid_216" class="sequence">D</text>
<text x="5164.1" y="3446.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-78.3,5164.1,3446.5)" class="sequence" id="seq_Aspartic-Acid_225">D</text>
<text x="4887.1" y="4138.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-58.9,4887.1,4138.0)" id="seq_Aspartic-Acid_269" class="sequence">D</text>
<text x="4632.7" y="4431.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-48.7,4632.7,4431.9)" class="sequence" id="seq_Aspartic-Acid_292">D</text>
<text x="4609.5" y="4478.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-47.4,4609.5,4478.7)" class="sequence" id="seq_Aspartic-Acid_295">D</text>
<text x="4563.1" y="4527.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-45.7,4563.1,4527.7)" class="sequence" id="seq_Aspartic-Acid_299">D</text>
<text x="4489.9" y="4566.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-43.6,4489.9,4566.2)" id="seq_Aspartic-Acid_303" class="sequence">D</text>
<text x="4093.7" y="4913.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-29.8,4093.7,4913.1)" class="sequence" id="seq_Aspartic-Acid_335">D</text>
<text x="3862.5" y="5019.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-23.1,3862.5,5019.1)" id="seq_Aspartic-Acid_350" class="sequence">D</text>
<text x="3780.5" y="5041.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-20.9,3780.5,5041.5)" id="seq_Aspartic-Acid_355" class="sequence">D</text>
<text x="3570.4" y="5085.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-15.3,3570.4,5085.0)" class="sequence" id="seq_Aspartic-Acid_367">D</text>
<text x="3572.6" y="5110.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-15.2,3572.6,5110.3)" class="sequence" id="seq_Aspartic-Acid_368">D</text>
<text x="3326.1" y="5136.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-8.7,3326.1,5136.9)" class="sequence" id="seq_Aspartic-Acid_382">D</text>
<text x="2587.9" y="5144.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(10.9,2587.9,5144.4)" class="sequence" id="seq_Aspartic-Acid_427">D</text>
<text x="2522.4" y="5128.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(12.6,2522.4,5128.7)" class="sequence" id="seq_Aspartic-Acid_431">D</text>
<text x="1898.5" y="4860.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(30.6,1898.5,4860.0)" class="sequence" id="seq_Aspartic-Acid_471">D</text>
<text x="1567.1" y="4679.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(40.5,1567.1,4679.4)" id="seq_Aspartic-Acid_494" class="sequence">D</text>
<text x="1519.0" y="4606.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(42.7,1519.0,4606.1)" class="sequence" id="seq_Aspartic-Acid_499">D</text>
<text x="1384.4" y="4501.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(47.1,1384.4,4501.5)" class="sequence" id="seq_Aspartic-Acid_509">D</text>
<text x="1047.8" y="4033.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(62.1,1047.8,4033.0)" id="seq_Aspartic-Acid_543" class="sequence">D</text>
<text x="801.8" y="3155.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(86.0,801.8,3155.1)" id="seq_Aspartic-Acid_597" class="sequence">D</text>
<text x="821.9" y="2951.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-88.7,821.9,2951.9)" id="seq_Aspartic-Acid_609" class="sequence">D</text>
<text x="871.2" y="2842.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-85.8,871.2,2842.3)" id="seq_Aspartic-Acid_615" class="sequence">D</text>
<text x="860.1" y="2601.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-79.5,860.1,2601.8)" id="seq_Aspartic-Acid_630" class="sequence">D</text>
<text x="902.2" y="2491.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-76.4,902.2,2491.2)" class="sequence" id="seq_Aspartic-Acid_637">D</text>
<text x="1075.7" y="1986.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-62.2,1075.7,1986.9)" class="sequence" id="seq_Aspartic-Acid_669">D</text>
<text x="1291.8" y="1647.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-51.6,1291.8,1647.7)" id="seq_Aspartic-Acid_693" class="sequence">D</text>
<text x="1526.5" y="1408.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-42.8,1526.5,1408.8)" id="seq_Aspartic-Acid_713" class="sequence">D</text>
<text x="1596.5" y="1336.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-40.2,1596.5,1336.3)" id="seq_Aspartic-Acid_719" class="sequence">D</text>
<text x="2291.9" y="937.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-18.9,2291.9,937.5)" class="sequence" id="seq_Aspartic-Acid_767">D</text>
<text x="2587.0" y="875.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-11.0,2587.0,875.1)" id="seq_Aspartic-Acid_785" class="sequence">D</text>
<text x="2818.8" y="849.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-4.8,2818.8,849.0)" id="seq_Aspartic-Acid_799" class="sequence">D</text>
<text x="2833.5" y="822.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-4.4,2833.5,822.7)" class="sequence" id="seq_Aspartic-Acid_800">D</text>
<text x="3286.6" y="846.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(367.6,3286.6,846.3)" id="seq_Valine_12" class="sequence">V</text>
<text x="3309.7" y="887.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(368.3,3309.7,887.9)" class="sequence" id="seq_Alanine_13">A</text>
<text x="3317.7" y="864.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(368.5,3317.7,864.9)" id="seq_Valine_14" class="sequence">V</text>
<text x="3337.8" y="843.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(368.9,3337.8,843.7)" id="seq_Threonine_15" class="sequence">T</text>
<text x="3358.5" y="895.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(369.7,3358.5,895.7)" id="seq_Alanine_16" class="sequence">A</text>
<text x="3367.0" y="872.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(369.8,3367.0,872.8)" class="sequence" id="seq_Alanine_17">A</text>
<text x="3415.3" y="885.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(371.1,3415.3,885.8)" id="seq_Threonine_20" class="sequence">T</text>
<text x="3505.5" y="926.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(373.7,3505.5,926.1)" id="seq_Alanine_25" class="sequence">A</text>
<text x="3513.6" y="903.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(373.8,3513.6,903.3)" id="seq_Lysine_26" class="sequence">K</text>
<text x="3535.6" y="884.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(374.2,3535.6,884.1)" class="sequence" id="seq_Threonine_27">T</text>
<text x="3598.9" y="951.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(376.3,3598.9,951.1)" class="sequence" id="seq_Lysine_31">K</text>
<text x="3631.4" y="915.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(376.9,3631.4,915.9)" class="sequence" id="seq_Asparagine_33">N</text>
<text x="3646.1" y="965.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(377.6,3646.1,965.5)" class="sequence" id="seq_Histidine_34">H</text>
<text x="3679.7" y="930.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(378.2,3679.7,930.1)" id="seq_Alanine_36" class="sequence">A</text>
<text x="3756.6" y="964.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(380.4,3756.6,964.4)" class="sequence" id="seq_Tyrosine_41">Y</text>
<text x="3834.8" y="994.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(382.6,3834.8,994.1)" id="seq_Alanine_46" class="sequence">A</text>
<text x="3876.5" y="1053.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(384.2,3876.5,1053.6)" class="sequence" id="seq_Asparagine_49">N</text>
<text x="3890.5" y="1033.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(384.4,3890.5,1033.6)" id="seq_Tyrosine_50" class="sequence">Y</text>
<text x="3915.7" y="1018.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(384.8,3915.7,1018.7)" id="seq_Asparagine_51" class="sequence">N</text>
<text x="3921.3" y="1074.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(385.6,3921.3,1074.4)" class="sequence" id="seq_Threonine_52">T</text>
<text x="3935.7" y="1054.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(385.7,3935.7,1054.7)" id="seq_Asparagine_53" class="sequence">N</text>
<text x="3959.3" y="1081.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(386.6,3959.3,1081.9)" class="sequence" id="seq_Threonine_55">T</text>
<text x="4008.1" y="1095.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(387.9,4008.1,1095.7)" id="seq_Asparagine_58" class="sequence">N</text>
<text x="4034.2" y="1082.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(388.3,4034.2,1082.4)" id="seq_Valine_59" class="sequence">V</text>
<text x="4054.8" y="1114.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(389.2,4054.8,1114.3)" class="sequence" id="seq_Asparagine_61">N</text>
<text x="4081.1" y="1159.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(390.4,4081.1,1159.4)" class="sequence" id="seq_Asparagine_63">N</text>
<text x="4097.1" y="1140.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(390.5,4097.1,1140.9)" class="sequence" id="seq_Asparagine_64">N</text>
<text x="4123.8" y="1128.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(391.0,4123.8,1128.9)" class="sequence" id="seq_Alanine_65">A</text>
<text x="4125.1" y="1185.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(391.8,4125.1,1185.9)" class="sequence" id="seq_Glycine_66">G</text>
<text x="4151.2" y="1202.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(392.6,4151.2,1202.4)" id="seq_Lysine_68" class="sequence">K</text>
<text x="4193.6" y="1206.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(393.6,4193.6,1206.2)" class="sequence" id="seq_Alanine_71">A</text>
<text x="4244.5" y="1220.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(395.0,4244.5,1220.3)" class="sequence" id="seq_Lysine_74">K</text>
<text x="4288.6" y="1273.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(396.7,4288.6,1273.1)" class="sequence" id="seq_Threonine_78">T</text>
<text x="4313.8" y="1294.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(397.6,4313.8,1294.8)" class="sequence" id="seq_Alanine_80">A</text>
<text x="4360.5" y="1316.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(398.9,4360.5,1316.3)" id="seq_Tyrosine_83" class="sequence">Y</text>
<text x="4439.6" y="1423.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(402.4,4439.6,1423.8)" class="sequence" id="seq_Asparagine_90">N</text>
<text x="4482.1" y="1405.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(402.9,4482.1,1405.9)" id="seq_Threonine_92" class="sequence">T</text>
<text x="4474.2" y="1456.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(403.7,4474.2,1456.1)" class="sequence" id="seq_Valine_93">V</text>
<text x="4494.0" y="1441.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(403.8,4494.0,1441.9)" class="sequence" id="seq_Lysine_94">K</text>
<text x="4567.3" y="1486.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(406.0,4567.3,1486.7)" id="seq_Alanine_99" class="sequence">A</text>
<text x="4590.0" y="1575.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(408.1,4590.0,1575.8)" id="seq_Asparagine_103" class="sequence">N</text>
<text x="4609.6" y="1561.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(408.2,4609.6,1561.6)" class="sequence" id="seq_Glycine_104">G</text>
<text x="4654.6" y="1588.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(409.5,4654.6,1588.8)" id="seq_Valine_107" class="sequence">V</text>
<text x="4696.0" y="1662.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(411.7,4696.0,1662.9)" id="seq_Lysine_112" class="sequence">K</text>
<text x="4712.4" y="1692.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(412.6,4712.4,1692.2)" class="sequence" id="seq_Lysine_114">K</text>
<text x="4740.6" y="1733.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(414.0,4740.6,1733.4)" id="seq_Asparagine_117" class="sequence">N</text>
<text x="4769.8" y="1732.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(414.4,4769.8,1732.9)" id="seq_Threonine_118" class="sequence">T</text>
<text x="4787.0" y="1782.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(415.7,4787.0,1782.0)" id="seq_Asparagine_121" class="sequence">N</text>
<text x="4779.8" y="1821.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(416.5,4779.8,1821.4)" id="seq_Threonine_122" class="sequence">T</text>
<text x="4817.0" y="1842.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(417.5,4817.0,1842.0)" class="sequence" id="seq_Threonine_125">T</text>
<text x="4826.1" y="1875.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(418.4,4826.1,1875.4)" id="seq_Tyrosine_127" class="sequence">Y</text>
<text x="4840.8" y="1919.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(419.6,4840.8,1919.1)" class="sequence" id="seq_Threonine_129">T</text>
<text x="4863.7" y="1910.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(419.7,4863.7,1910.8)" class="sequence" id="seq_Glycine_130">G</text>
<text x="4892.9" y="1913.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(420.1,4892.9,1913.3)" id="seq_Lysine_131" class="sequence">K</text>
<text x="4865.3" y="1962.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(420.9,4865.3,1962.0)" id="seq_Valine_132" class="sequence">V</text>
<text x="4916.6" y="1957.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(421.5,4916.6,1957.8)" class="sequence" id="seq_Asparagine_134">N</text>
<text x="4940.2" y="2002.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(422.8,4940.2,2002.4)" class="sequence" id="seq_Asparagine_137">N</text>
<text x="5006.7" y="2156.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(427.2,5006.7,2156.7)" id="seq_Glycine_147" class="sequence">G</text>
<text x="4997.2" y="2196.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(428.1,4997.2,2196.7)" id="seq_Asparagine_149" class="sequence">N</text>
<text x="5008.2" y="2276.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(430.2,5008.2,2276.2)" class="sequence" id="seq_Alanine_153">A</text>
<text x="5032.3" y="2272.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(430.3,5032.3,2272.3)" id="seq_Asparagine_154" class="sequence">N</text>
<text x="5034.6" y="2354.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(432.4,5034.6,2354.1)" class="sequence" id="seq_Tyrosine_158">Y</text>
<text x="5058.8" y="2351.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(432.5,5058.8,2351.1)" id="seq_Asparagine_159" class="sequence">N</text>
<text x="5062.3" y="2448.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(435.0,5062.3,2448.9)" class="sequence" id="seq_Alanine_164">A</text>
<text x="5109.5" y="2561.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(438.2,5109.5,2561.2)" id="seq_Valine_172" class="sequence">V</text>
<text x="5136.3" y="2572.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(438.7,5136.3,2572.7)" class="sequence" id="seq_Glycine_173">G</text>
<text x="5099.0" y="2611.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(439.5,5099.0,2611.3)" class="sequence" id="seq_Lysine_174">K</text>
<text x="5130.5" y="2692.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(441.8,5130.5,2692.3)" id="seq_Tyrosine_180" class="sequence">Y</text>
<text x="5158.9" y="2739.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(443.1,5158.9,2739.0)" class="sequence" id="seq_Tyrosine_183">Y</text>
<text x="5122.4" y="2772.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(443.9,5122.4,2772.1)" class="sequence" id="seq_Valine_184">V</text>
<text x="5146.8" y="2774.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(444.0,5146.8,2774.0)" class="sequence" id="seq_Valine_185">V</text>
<text x="5144.0" y="2807.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(444.9,5144.0,2807.7)" class="sequence" id="seq_Lysine_187">K</text>
<text x="5169.4" y="2822.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(445.3,5169.4,2822.2)" id="seq_Asparagine_188" class="sequence">N</text>
<text x="5131.7" y="2886.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(447.0,5131.7,2886.9)" class="sequence" id="seq_Alanine_191">A</text>
<text x="5178.6" y="2905.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(447.5,5178.6,2905.8)" class="sequence" id="seq_Alanine_193">A</text>
<text x="5133.7" y="2936.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(448.3,5133.7,2936.2)" class="sequence" id="seq_Asparagine_194">N</text>
<text x="5157.8" y="2940.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(448.4,5157.8,2940.0)" class="sequence" id="seq_Histidine_195">H</text>
<text x="5182.2" y="2956.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(448.8,5182.2,2956.2)" class="sequence" id="seq_Tyrosine_196">Y</text>
<text x="5206.6" y="3006.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-89.8,5206.6,3006.7)" class="sequence" id="seq_Tyrosine_199">Y</text>
<text x="5163.3" y="3037.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-89.0,5163.3,3037.4)" class="sequence" id="seq_Glycine_200">G</text>
<text x="5160.6" y="3068.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-88.2,5160.6,3068.7)" class="sequence" id="seq_Tyrosine_202">Y</text>
<text x="5183.0" y="3107.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-87.2,5183.0,3107.7)" id="seq_Glycine_205" class="sequence">G</text>
<text x="5156.3" y="3151.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-86.0,5156.3,3151.9)" class="sequence" id="seq_Tyrosine_207">Y</text>
<text x="5198.6" y="3176.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-85.4,5198.6,3176.5)" class="sequence" id="seq_Valine_209">V</text>
<text x="5152.2" y="3201.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-84.6,5152.2,3201.7)" id="seq_Asparagine_210" class="sequence">N</text>
<text x="5177.7" y="3208.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-84.5,5177.7,3208.7)" id="seq_Glycine_211" class="sequence">G</text>
<text x="5197.9" y="3227.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-84.1,5197.9,3227.8)" class="sequence" id="seq_Valine_212">V</text>
<text x="5173.3" y="3259.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-83.2,5173.3,3259.1)" id="seq_Glycine_214" class="sequence">G</text>
<text x="5142.8" y="3284.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-82.4,5142.8,3284.5)" class="sequence" id="seq_Tyrosine_215">Y</text>
<text x="5138.2" y="3317.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-81.6,5138.2,3317.5)" class="sequence" id="seq_Tyrosine_217">Y</text>
<text x="5131.9" y="3369.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-80.2,5131.9,3369.2)" id="seq_Glycine_220" class="sequence">G</text>
<text x="5111.0" y="3465.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-77.6,5111.0,3465.0)" class="sequence" id="seq_Valine_226">V</text>
<text x="5149.3" y="3495.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-77.0,5149.3,3495.5)" class="sequence" id="seq_Histidine_228">H</text>
<text x="5099.7" y="3513.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-76.3,5099.7,3513.7)" class="sequence" id="seq_Threonine_229">T</text>
<text x="5091.3" y="3585.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-74.4,5091.3,3585.2)" class="sequence" id="seq_Lysine_234">K</text>
<text x="5084.9" y="3635.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-73.0,5084.9,3635.7)" id="seq_Tyrosine_237" class="sequence">Y</text>
<text x="5076.7" y="3668.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-72.2,5076.7,3668.4)" id="seq_Histidine_239" class="sequence">H</text>
<text x="5064.3" y="3699.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-71.3,5064.3,3699.7)" id="seq_Histidine_241" class="sequence">H</text>
<text x="5081.5" y="3723.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-70.8,5081.5,3723.5)" class="sequence" id="seq_Alanine_242">A</text>
<text x="5032.2" y="3736.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-70.1,5032.2,3736.9)" class="sequence" id="seq_Tyrosine_243">Y</text>
<text x="5053.2" y="3749.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-69.9,5053.2,3749.3)" class="sequence" id="seq_Valine_244">V</text>
<text x="5039.5" y="3780.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-69.1,5039.5,3780.2)" class="sequence" id="seq_Alanine_246">A</text>
<text x="5055.8" y="3804.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-68.6,5055.8,3804.6)" id="seq_Lysine_247" class="sequence">K</text>
<text x="5038.5" y="3852.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-67.3,5038.5,3852.7)" class="sequence" id="seq_Asparagine_250">N</text>
<text x="4982.9" y="3860.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-66.5,4982.9,3860.7)" class="sequence" id="seq_Alanine_251">A</text>
<text x="5003.1" y="3874.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-66.4,5003.1,3874.4)" id="seq_Tyrosine_252" class="sequence">Y</text>
<text x="4998.7" y="3928.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-65.1,4998.7,3928.1)" class="sequence" id="seq_Tyrosine_255">Y</text>
<text x="4934.7" y="3990.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-62.9,4934.7,3990.8)" id="seq_Glycine_260" class="sequence">G</text>
<text x="4927.8" y="4063.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-61.1,4927.8,4063.5)" class="sequence" id="seq_Alanine_264">A</text>
<text x="4878.7" y="4069.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-60.4,4878.7,4069.3)" id="seq_Histidine_265" class="sequence">H</text>
<text x="4876.9" y="4112.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-59.3,4876.9,4112.2)" id="seq_Glycine_268" class="sequence">G</text>
<text x="4818.8" y="4171.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-57.2,4818.8,4171.8)" class="sequence" id="seq_Glycine_272">G</text>
<text x="4781.3" y="4224.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-55.5,4781.3,4224.6)" id="seq_Threonine_276" class="sequence">T</text>
<text x="4798.5" y="4241.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-55.4,4798.5,4241.9)" class="sequence" id="seq_Asparagine_277">N</text>
<text x="4774.3" y="4266.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-54.5,4774.3,4266.0)" id="seq_Tyrosine_279" class="sequence">Y</text>
<text x="4760.5" y="4318.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-53.2,4760.5,4318.7)" id="seq_Threonine_282" class="sequence">T</text>
<text x="4712.7" y="4318.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-52.4,4712.7,4318.9)" id="seq_Valine_283" class="sequence">V</text>
<text x="4705.8" y="4361.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-51.4,4705.8,4361.7)" id="seq_Glycine_286" class="sequence">G</text>
<text x="4659.3" y="4385.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-50.1,4659.3,4385.4)" class="sequence" id="seq_Lysine_288">K</text>
<text x="4682.0" y="4429.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-49.6,4682.0,4429.9)" class="sequence" id="seq_Asparagine_290">N</text>
<text x="4640.3" y="4461.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-48.3,4640.3,4461.1)" class="sequence" id="seq_Valine_293">V</text>
<text x="4594.8" y="4459.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-47.5,4594.8,4459.2)" id="seq_Threonine_294" class="sequence">T</text>
<text x="4572.2" y="4483.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-46.7,4572.2,4483.6)" id="seq_Alanine_296" class="sequence">A</text>
<text x="4549.1" y="4507.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-45.8,4549.1,4507.7)" class="sequence" id="seq_Valine_298">V</text>
<text x="4512.4" y="4544.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-44.4,4512.4,4544.5)" id="seq_Alanine_301" class="sequence">A</text>
<text x="4503.8" y="4587.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-43.4,4503.8,4587.5)" id="seq_Alanine_304" class="sequence">A</text>
<text x="4452.0" y="4656.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-41.2,4452.0,4656.3)" id="seq_Lysine_309" class="sequence">K</text>
<text x="4412.7" y="4662.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-40.4,4412.7,4662.5)" id="seq_Alanine_311" class="sequence">A</text>
<text x="4386.9" y="4684.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-39.5,4386.9,4684.0)" id="seq_Lysine_313" class="sequence">K</text>
<text x="4358.7" y="4729.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-38.1,4358.7,4729.8)" class="sequence" id="seq_Valine_316">V</text>
<text x="4321.0" y="4736.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-37.3,4321.0,4736.2)" class="sequence" id="seq_Valine_318">V</text>
<text x="4323.2" y="4767.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-36.8,4323.2,4767.2)" id="seq_Glycine_319" class="sequence">G</text>
<text x="4278.5" y="4792.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-35.5,4278.5,4792.4)" id="seq_Asparagine_322" class="sequence">N</text>
<text x="4245.0" y="4803.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-34.6,4245.0,4803.7)" id="seq_Threonine_324" class="sequence">T</text>
<text x="4215.9" y="4821.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-33.7,4215.9,4821.0)" id="seq_Glycine_326" class="sequence">G</text>
<text x="4155.0" y="4850.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-32.0,4155.0,4850.8)" class="sequence" id="seq_Asparagine_330">N</text>
<text x="4096.4" y="4883.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-30.2,4096.4,4883.8)" class="sequence" id="seq_Threonine_334">T</text>
<text x="4055.4" y="4913.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-28.9,4055.4,4913.9)" class="sequence" id="seq_Glycine_337">G</text>
<text x="4051.1" y="4941.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-28.4,4051.1,4941.4)" class="sequence" id="seq_Asparagine_338">N</text>
<text x="4003.8" y="4914.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-27.7,4003.8,4914.5)" id="seq_Valine_339" class="sequence">V</text>
<text x="3972.3" y="4930.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-26.7,3972.3,4930.6)" class="sequence" id="seq_Lysine_341">K</text>
<text x="3980.9" y="4953.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-26.7,3980.9,4953.2)" id="seq_Alanine_342" class="sequence">A</text>
<text x="3976.4" y="4982.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-26.2,3976.4,4982.2)" id="seq_Valine_343" class="sequence">V</text>
<text x="3935.0" y="4974.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-25.3,3935.0,4974.5)" class="sequence" id="seq_Histidine_345">H</text>
<text x="3904.0" y="4987.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-24.5,3904.0,4987.7)" id="seq_Threonine_347" class="sequence">T</text>
<text x="3898.5" y="5016.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-24.0,3898.5,5016.6)" class="sequence" id="seq_Alanine_348">A</text>
<text x="3826.0" y="5019.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-22.2,3826.0,5019.2)" id="seq_Glycine_352" class="sequence">G</text>
<text x="3818.6" y="5046.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-21.8,3818.6,5046.0)" class="sequence" id="seq_Lysine_353">K</text>
<text x="3775.0" y="5020.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-21.0,3775.0,5020.1)" class="sequence" id="seq_Glycine_354">G</text>
<text x="3669.0" y="5079.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-17.8,3669.0,5079.7)" class="sequence" id="seq_Threonine_362">T</text>
<text x="3660.1" y="5107.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-17.4,3660.1,5107.7)" class="sequence" id="seq_Lysine_363">K</text>
<text x="3618.5" y="5071.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-16.6,3618.5,5071.3)" class="sequence" id="seq_Valine_364">V</text>
<text x="3621.0" y="5095.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-16.5,3621.0,5095.6)" id="seq_Threonine_365" class="sequence">T</text>
<text x="3526.5" y="5134.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-13.9,3526.5,5134.7)" class="sequence" id="seq_Threonine_371">T</text>
<text x="3489.7" y="5105.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-13.1,3489.7,5105.5)" class="sequence" id="seq_Alanine_372">A</text>
<text x="3490.7" y="5129.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-13.0,3490.7,5129.9)" id="seq_Histidine_373" class="sequence">H</text>
<text x="3479.4" y="5157.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-12.5,3479.4,5157.0)" class="sequence" id="seq_Histidine_374">H</text>
<text x="3406.5" y="5125.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-10.8,3406.5,5125.1)" id="seq_Glycine_377" class="sequence">G</text>
<text x="3408.2" y="5147.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-10.8,3408.2,5147.2)" class="sequence" id="seq_Histidine_378">H</text>
<text x="3360.4" y="5167.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-9.4,3360.4,5167.9)" id="seq_Tyrosine_381" class="sequence">Y</text>
<text x="3293.1" y="5141.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-7.8,3293.1,5141.7)" class="sequence" id="seq_Alanine_384">A</text>
<text x="3291.8" y="5166.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-7.7,3291.8,5166.1)" id="seq_Tyrosine_385" class="sequence">Y</text>
<text x="3278.1" y="5192.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-7.2,3278.1,5192.1)" id="seq_Alanine_386" class="sequence">A</text>
<text x="3243.5" y="5147.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-6.5,3243.5,5147.9)" id="seq_Alanine_387" class="sequence">A</text>
<text x="3127.3" y="5157.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-3.4,3127.3,5157.9)" id="seq_Asparagine_394" class="sequence">N</text>
<text x="3124.2" y="5184.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-3.3,3124.2,5184.1)" class="sequence" id="seq_Glycine_395">G</text>
<text x="3108.5" y="5207.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-2.8,3108.5,5207.0)" class="sequence" id="seq_Alanine_396">A</text>
<text x="3077.3" y="5160.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-2.1,3077.3,5160.3)" class="sequence" id="seq_Asparagine_397">N</text>
<text x="3057.4" y="5206.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-1.5,3057.4,5206.9)" class="sequence" id="seq_Glycine_399">G</text>
<text x="3023.0" y="5180.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-0.6,3023.0,5180.5)" class="sequence" id="seq_Histidine_401">H</text>
<text x="2989.4" y="5181.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(0.3,2989.4,5181.6)" id="seq_Alanine_403" class="sequence">A</text>
<text x="2972.3" y="5205.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(0.7,2972.3,5205.5)" class="sequence" id="seq_Valine_404">V</text>
<text x="2944.0" y="5162.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(1.5,2944.0,5162.9)" class="sequence" id="seq_Glycine_405">G</text>
<text x="2836.9" y="5193.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(4.3,2836.9,5193.6)" class="sequence" id="seq_Alanine_412">A</text>
<text x="2811.0" y="5153.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(5.0,2811.0,5153.4)" class="sequence" id="seq_Alanine_413">A</text>
<text x="2804.3" y="5176.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(5.1,2804.3,5176.9)" class="sequence" id="seq_Threonine_414">T</text>
<text x="2771.0" y="5171.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(6.0,2771.0,5171.6)" id="seq_Lysine_416" class="sequence">K</text>
<text x="2751.6" y="5193.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(6.5,2751.6,5193.6)" id="seq_Histidine_417" class="sequence">H</text>
<text x="2721.4" y="5161.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(7.3,2721.4,5161.8)" id="seq_Lysine_419" class="sequence">K</text>
<text x="2669.3" y="5168.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(8.7,2669.3,5168.6)" id="seq_Glycine_422" class="sequence">G</text>
<text x="2500.4" y="5149.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(13.1,2500.4,5149.3)" class="sequence" id="seq_Asparagine_432">N</text>
<text x="2473.3" y="5117.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(14.0,2473.3,5117.1)" class="sequence" id="seq_Threonine_434">T</text>
<text x="2421.9" y="5114.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(15.3,2421.9,5114.0)" id="seq_Asparagine_437" class="sequence">N</text>
<text x="2360.5" y="5083.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(17.1,2360.5,5083.7)" class="sequence" id="seq_Lysine_441">K</text>
<text x="2320.5" y="5052.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(18.3,2320.5,5052.1)" class="sequence" id="seq_Alanine_443">A</text>
<text x="2288.8" y="5085.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(18.8,2288.8,5085.7)" id="seq_Threonine_445" class="sequence">T</text>
<text x="2267.5" y="5044.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(19.7,2267.5,5044.4)" class="sequence" id="seq_Valine_447">V</text>
<text x="2242.8" y="5063.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(20.2,2242.8,5063.1)" class="sequence" id="seq_Glycine_448">G</text>
<text x="2226.4" y="5018.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(21.0,2226.4,5018.5)" class="sequence" id="seq_Threonine_449">T</text>
<text x="2170.4" y="5016.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(22.4,2170.4,5016.7)" class="sequence" id="seq_Threonine_453">T</text>
<text x="2145.5" y="5032.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(22.8,2145.5,5032.3)" class="sequence" id="seq_Tyrosine_454">Y</text>
<text x="2092.8" y="4984.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(24.6,2092.8,4984.1)" class="sequence" id="seq_Lysine_458">K</text>
<text x="2015.2" y="4924.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(27.1,2015.2,4924.3)" class="sequence" id="seq_Valine_463">V</text>
<text x="1976.5" y="4952.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(27.7,1976.5,4952.7)" id="seq_Lysine_465" class="sequence">K</text>
<text x="1970.1" y="4902.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(28.4,1970.1,4902.8)" id="seq_Glycine_466" class="sequence">G</text>
<text x="1907.5" y="4902.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(29.9,1907.5,4902.2)" class="sequence" id="seq_Lysine_470">K</text>
<text x="1836.0" y="4857.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(32.1,1836.0,4857.0)" class="sequence" id="seq_Lysine_475">K</text>
<text x="1827.7" y="4816.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(32.8,1827.7,4816.1)" class="sequence" id="seq_Lysine_476">K</text>
<text x="1758.5" y="4769.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(35.1,1758.5,4769.6)" class="sequence" id="seq_Lysine_481">K</text>
<text x="1696.5" y="4761.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(36.5,1696.5,4761.9)" class="sequence" id="seq_Valine_485">V</text>
<text x="1690.1" y="4722.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(37.3,1690.1,4722.0)" class="sequence" id="seq_Glycine_486">G</text>
<text x="1673.1" y="4736.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(37.4,1673.1,4736.8)" class="sequence" id="seq_Valine_487">V</text>
<text x="1645.1" y="4745.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(37.8,1645.1,4745.5)" class="sequence" id="seq_Valine_488">V</text>
<text x="1608.8" y="4709.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(39.1,1608.8,4709.0)" class="sequence" id="seq_Valine_491">V</text>
<text x="1595.5" y="4672.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(40.0,1595.5,4672.1)" id="seq_Histidine_493" class="sequence">H</text>
<text x="1558.6" y="4637.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(41.4,1558.6,4637.6)" class="sequence" id="seq_Threonine_496">T</text>
<text x="1530.0" y="4644.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(41.8,1530.0,4644.4)" class="sequence" id="seq_Tyrosine_497">Y</text>
<text x="1495.1" y="4582.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(43.6,1495.1,4582.3)" class="sequence" id="seq_Alanine_501">A</text>
<text x="1454.2" y="4511.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(45.7,1454.2,4511.0)" id="seq_Histidine_505" class="sequence">H</text>
<text x="1433.8" y="4524.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(45.8,1433.8,4524.5)" id="seq_Valine_506" class="sequence">V</text>
<text x="1413.4" y="4497.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(46.7,1413.4,4497.5)" id="seq_Asparagine_508" class="sequence">N</text>
<text x="1397.1" y="4450.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(47.9,1397.1,4450.3)" class="sequence" id="seq_Tyrosine_510">Y</text>
<text x="1342.4" y="4387.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(50.1,1342.4,4387.5)" id="seq_Tyrosine_515" class="sequence">Y</text>
<text x="1321.1" y="4399.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(50.2,1321.1,4399.4)" id="seq_Tyrosine_516" class="sequence">Y</text>
<text x="1291.8" y="4401.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(50.6,1291.8,4401.6)" id="seq_Threonine_517" class="sequence">T</text>
<text x="1290.7" y="4359.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(51.5,1290.7,4359.0)" id="seq_Threonine_519" class="sequence">T</text>
<text x="1273.2" y="4330.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(52.4,1273.2,4330.0)" id="seq_Tyrosine_521" class="sequence">Y</text>
<text x="1202.3" y="4236.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(55.5,1202.3,4236.1)" id="seq_Alanine_528" class="sequence">A</text>
<text x="1174.2" y="4157.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(57.6,1174.2,4157.3)" class="sequence" id="seq_Alanine_532">A</text>
<text x="1152.6" y="4168.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(57.7,1152.6,4168.0)" class="sequence" id="seq_Alanine_533">A</text>
<text x="1123.3" y="4166.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(58.1,1123.3,4166.4)" class="sequence" id="seq_Lysine_534">K</text>
<text x="1149.0" y="4116.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(58.9,1149.0,4116.5)" class="sequence" id="seq_Histidine_535">H</text>
<text x="1098.5" y="4121.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(59.5,1098.5,4121.7)" id="seq_Glycine_537" class="sequence">G</text>
<text x="1078.3" y="4074.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(60.8,1078.3,4074.5)" class="sequence" id="seq_Histidine_540">H</text>
<text x="1099.4" y="4029.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(61.6,1099.4,4029.7)" id="seq_Lysine_541" class="sequence">K</text>
<text x="1039.7" y="3980.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(63.4,1039.7,3980.0)" id="seq_Asparagine_546" class="sequence">N</text>
<text x="1033.8" y="3945.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(64.3,1033.8,3945.3)" id="seq_Threonine_548" class="sequence">T</text>
<text x="1019.5" y="3914.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(65.2,1019.5,3914.9)" class="sequence" id="seq_Alanine_550">A</text>
<text x="988.8" y="3910.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(65.6,988.8,3910.3)" id="seq_Glycine_551" class="sequence">G</text>
<text x="993.3" y="3871.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(66.5,993.3,3871.3)" id="seq_Lysine_553" class="sequence">K</text>
<text x="957.0" y="3831.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(67.9,957.0,3831.4)" class="sequence" id="seq_Asparagine_556">N</text>
<text x="928.4" y="3751.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(70.1,928.4,3751.4)" id="seq_Glycine_561" class="sequence">G</text>
<text x="940.6" y="3713.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(70.9,940.6,3713.9)" class="sequence" id="seq_Lysine_562">K</text>
<text x="932.4" y="3630.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(73.0,932.4,3630.7)" class="sequence" id="seq_Threonine_567">T</text>
<text x="886.0" y="3622.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(73.6,886.0,3622.3)" class="sequence" id="seq_Alanine_569">A</text>
<text x="876.1" y="3572.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(74.9,876.1,3572.2)" id="seq_Asparagine_572" class="sequence">N</text>
<text x="905.5" y="3534.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(75.7,905.5,3534.4)" class="sequence" id="seq_Valine_573">V</text>
<text x="881.1" y="3535.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(75.8,881.1,3535.9)" id="seq_Valine_574" class="sequence">V</text>
<text x="851.8" y="3525.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(76.2,851.8,3525.8)" id="seq_Glycine_575" class="sequence">G</text>
<text x="893.7" y="3485.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(77.0,893.7,3485.9)" id="seq_Alanine_576" class="sequence">A</text>
<text x="869.3" y="3486.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(77.1,869.3,3486.8)" class="sequence" id="seq_Lysine_577">K</text>
<text x="842.1" y="3475.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(77.6,842.1,3475.5)" class="sequence" id="seq_Asparagine_578">N</text>
<text x="852.7" y="3438.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(78.5,852.7,3438.6)" id="seq_Asparagine_580" class="sequence">N</text>
<text x="876.5" y="3404.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(79.2,876.5,3404.3)" class="sequence" id="seq_Valine_581">V</text>
<text x="846.6" y="3337.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(81.1,846.6,3337.0)" id="seq_Asparagine_586" class="sequence">N</text>
<text x="820.3" y="3323.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(81.5,820.3,3323.9)" class="sequence" id="seq_Tyrosine_587">Y</text>
<text x="812.6" y="3222.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(84.2,812.6,3222.3)" id="seq_Threonine_593" class="sequence">T</text>
<text x="827.0" y="3170.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(85.5,827.0,3170.1)" id="seq_Lysine_596" class="sequence">K</text>
<text x="815.7" y="3120.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(86.8,815.7,3120.3)" id="seq_Asparagine_599" class="sequence">N</text>
<text x="840.2" y="3090.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(87.6,840.2,3090.1)" id="seq_Lysine_600" class="sequence">K</text>
<text x="816.1" y="3086.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(87.7,816.1,3086.5)" class="sequence" id="seq_Asparagine_601">N</text>
<text x="799.6" y="3036.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(89.1,799.6,3036.2)" id="seq_Valine_604" class="sequence">V</text>
<text x="836.4" y="3006.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(89.8,836.4,3006.8)" id="seq_Glycine_605" class="sequence">G</text>
<text x="845.6" y="2969.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-89.2,845.6,2969.1)" id="seq_Threonine_608" class="sequence">T</text>
<text x="846.4" y="2885.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-87.0,846.4,2885.9)" class="sequence" id="seq_Tyrosine_613">Y</text>
<text x="823.4" y="2867.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-86.5,823.4,2867.9)" class="sequence" id="seq_Alanine_614">A</text>
<text x="846.0" y="2785.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-84.3,846.0,2785.7)" id="seq_Lysine_619" class="sequence">K</text>
<text x="878.8" y="2760.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-83.6,878.8,2760.4)" class="sequence" id="seq_Valine_620">V</text>
<text x="840.4" y="2683.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-81.7,840.4,2683.7)" class="sequence" id="seq_Lysine_625">K</text>
<text x="873.2" y="2655.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-80.8,873.2,2655.0)" id="seq_Alanine_627" class="sequence">A</text>
<text x="880.7" y="2622.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-79.9,880.7,2622.6)" id="seq_Glycine_629" class="sequence">G</text>
<text x="906.8" y="2581.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-78.7,906.8,2581.6)" class="sequence" id="seq_Lysine_631">K</text>
<text x="884.1" y="2572.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-78.6,884.1,2572.5)" id="seq_Alanine_632" class="sequence">A</text>
<text x="864.0" y="2551.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-78.1,864.0,2551.2)" id="seq_Tyrosine_633" class="sequence">Y</text>
<text x="924.4" y="2501.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-76.5,924.4,2501.2)" id="seq_Asparagine_636" class="sequence">N</text>
<text x="932.4" y="2469.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-75.6,932.4,2469.3)" class="sequence" id="seq_Asparagine_638">N</text>
<text x="945.2" y="2421.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-74.3,945.2,2421.6)" id="seq_Tyrosine_641" class="sequence">Y</text>
<text x="932.4" y="2326.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-72.0,932.4,2326.2)" class="sequence" id="seq_Valine_647">V</text>
<text x="979.4" y="2311.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-71.2,979.4,2311.6)" class="sequence" id="seq_Alanine_648">A</text>
<text x="958.1" y="2299.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-71.1,958.1,2299.6)" id="seq_Tyrosine_649" class="sequence">Y</text>
<text x="940.9" y="2276.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-70.6,940.9,2276.0)" class="sequence" id="seq_Alanine_650">A</text>
<text x="1014.1" y="2217.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-68.5,1014.1,2217.1)" class="sequence" id="seq_Tyrosine_654">Y</text>
<text x="1010.7" y="2177.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-67.5,1010.7,2177.4)" id="seq_Lysine_657" class="sequence">K</text>
<text x="995.0" y="2152.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-67.1,995.0,2152.8)" id="seq_Valine_658" class="sequence">V</text>
<text x="1044.9" y="2143.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-66.3,1044.9,2143.0)" class="sequence" id="seq_Lysine_659">K</text>
<text x="1024.8" y="2129.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-66.2,1024.8,2129.2)" class="sequence" id="seq_Asparagine_660">N</text>
<text x="1062.7" y="2036.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-63.6,1062.7,2036.6)" class="sequence" id="seq_Glycine_666">G</text>
<text x="1124.6" y="1980.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-61.5,1124.6,1980.5)" id="seq_Valine_670" class="sequence">V</text>
<text x="1094.4" y="1939.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-60.9,1094.4,1939.8)" class="sequence" id="seq_Valine_672">V</text>
<text x="1148.6" y="1937.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-60.1,1148.6,1937.4)" id="seq_Alanine_673" class="sequence">A</text>
<text x="1130.1" y="1921.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-60.0,1130.1,1921.5)" class="sequence" id="seq_Asparagine_674">N</text>
<text x="1152.1" y="1895.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-59.1,1152.1,1895.9)" id="seq_Lysine_676" class="sequence">K</text>
<text x="1195.9" y="1805.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-56.5,1195.9,1805.6)" class="sequence" id="seq_Asparagine_682">N</text>
<text x="1216.6" y="1759.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-55.2,1216.6,1759.0)" id="seq_Valine_685" class="sequence">V</text>
<text x="1264.2" y="1757.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-54.4,1264.2,1757.5)" id="seq_Threonine_686" class="sequence">T</text>
<text x="1247.3" y="1739.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-54.3,1247.3,1739.8)" id="seq_Alanine_687" class="sequence">A</text>
<text x="1268.6" y="1714.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-53.4,1268.6,1714.2)" class="sequence" id="seq_Lysine_689">K</text>
<text x="1259.4" y="1686.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-53.0,1259.4,1686.4)" id="seq_Asparagine_690" class="sequence">N</text>
<text x="1313.4" y="1691.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-52.2,1313.4,1691.5)" class="sequence" id="seq_Valine_691">V</text>
<text x="1386.4" y="1602.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-49.1,1386.4,1602.5)" id="seq_Threonine_698" class="sequence">T</text>
<text x="1367.2" y="1557.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-48.5,1367.2,1557.6)" id="seq_Valine_700" class="sequence">V</text>
<text x="1407.4" y="1548.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-47.7,1407.4,1548.7)" id="seq_Lysine_702" class="sequence">K</text>
<text x="1401.0" y="1520.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-47.2,1401.0,1520.2)" class="sequence" id="seq_Alanine_703">A</text>
<text x="1530.7" y="1437.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-43.2,1530.7,1437.7)" id="seq_Asparagine_712" class="sequence">N</text>
<text x="1570.6" y="1414.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-42.0,1570.6,1414.6)" id="seq_Alanine_714" class="sequence">A</text>
<text x="1599.3" y="1365.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-40.6,1599.3,1365.4)" class="sequence" id="seq_Asparagine_718">N</text>
<text x="1645.5" y="1350.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-39.4,1645.5,1350.2)" class="sequence" id="seq_Asparagine_720">N</text>
<text x="1702.8" y="1282.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-37.1,1702.8,1282.1)" id="seq_Glycine_726" class="sequence">G</text>
<text x="1776.5" y="1250.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-35.0,1776.5,1250.7)" id="seq_Threonine_730" class="sequence">T</text>
<text x="1770.0" y="1204.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-34.4,1770.0,1204.2)" class="sequence" id="seq_Glycine_732">G</text>
<text x="1810.8" y="1174.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-33.1,1810.8,1174.6)" class="sequence" id="seq_Asparagine_735">N</text>
<text x="1879.1" y="1157.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-31.3,1879.1,1157.6)" id="seq_Valine_739" class="sequence">V</text>
<text x="1962.6" y="1102.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-28.7,1962.6,1102.4)" id="seq_Valine_745" class="sequence">V</text>
<text x="1996.1" y="1094.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-27.8,1996.1,1094.6)" id="seq_Glycine_747" class="sequence">G</text>
<text x="1999.8" y="1065.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-27.3,1999.8,1065.6)" id="seq_Valine_748" class="sequence">V</text>
<text x="2044.9" y="1090.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-26.6,2044.9,1090.9)" class="sequence" id="seq_Valine_749">V</text>
<text x="2076.3" y="1075.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-25.6,2076.3,1075.6)" class="sequence" id="seq_Glycine_751">G</text>
<text x="2068.1" y="1052.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-25.6,2068.1,1052.8)" id="seq_Valine_752" class="sequence">V</text>
<text x="2104.1" y="1051.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-24.7,2104.1,1051.4)" class="sequence" id="seq_Valine_754">V</text>
<text x="2109.3" y="1022.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-24.2,2109.3,1022.7)" id="seq_Valine_755" class="sequence">V</text>
<text x="2151.1" y="1041.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-23.4,2151.1,1041.4)" class="sequence" id="seq_Glycine_756">G</text>
<text x="2159.2" y="1011.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-22.9,2159.2,1011.8)" class="sequence" id="seq_Valine_758">V</text>
<text x="2234.6" y="976.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-20.7,2234.6,976.2)" id="seq_Threonine_763" class="sequence">T</text>
<text x="2271.6" y="993.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-20.0,2271.6,993.5)" id="seq_Glycine_764" class="sequence">G</text>
<text x="2331.2" y="949.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-18.1,2331.2,949.7)" class="sequence" id="seq_Lysine_769">K</text>
<text x="2339.8" y="921.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-17.6,2339.8,921.7)" class="sequence" id="seq_Lysine_770">K</text>
<text x="2380.9" y="957.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-16.9,2380.9,957.1)" id="seq_Lysine_771" class="sequence">K</text>
<text x="2378.2" y="932.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-16.7,2378.2,932.8)" class="sequence" id="seq_Asparagine_772">N</text>
<text x="2387.4" y="905.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-16.3,2387.4,905.1)" id="seq_Lysine_773" class="sequence">K</text>
<text x="2428.3" y="943.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-15.5,2428.3,943.3)" id="seq_Alanine_774" class="sequence">A</text>
<text x="2459.3" y="914.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-14.5,2459.3,914.3)" id="seq_Glycine_777" class="sequence">G</text>
<text x="2491.6" y="906.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-13.6,2491.6,906.2)" class="sequence" id="seq_Asparagine_779">N</text>
<text x="2540.0" y="915.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-12.4,2540.0,915.5)" id="seq_Tyrosine_781" class="sequence">Y</text>
<text x="2539.3" y="891.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-12.3,2539.3,891.1)" class="sequence" id="seq_Alanine_782">A</text>
<text x="2636.3" y="866.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-9.7,2636.3,866.1)" class="sequence" id="seq_Lysine_788">K</text>
<text x="2671.4" y="890.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-8.9,2671.4,890.8)" id="seq_Glycine_789" class="sequence">G</text>
<text x="2683.7" y="844.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-8.3,2683.7,844.4)" class="sequence" id="seq_Asparagine_791">N</text>
<text x="2718.2" y="884.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-7.6,2718.2,884.0)" id="seq_Asparagine_792" class="sequence">N</text>
<text x="2733.3" y="835.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-7.0,2733.3,835.7)" class="sequence" id="seq_Glycine_794">G</text>
<text x="2783.6" y="831.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-5.7,2783.6,831.1)" class="sequence" id="seq_Asparagine_797">N</text>
<text x="2816.4" y="873.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-4.9,2816.4,873.3)" id="seq_Threonine_798" class="sequence">T</text>
<text x="2865.6" y="869.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-3.6,2865.6,869.6)" class="sequence" id="seq_Valine_801">V</text>
<text x="2900.5" y="867.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-2.7,2900.5,867.7)" id="seq_Threonine_803" class="sequence">T</text>
<text x="4888.4" y="1954.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(421.0,4888.4,1954.2)" class="sequence" id="seq_Cysteine_133">C</text>
<text x="4945.7" y="2074.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(424.6,4945.7,2074.3)" class="sequence" id="seq_Cysteine_141">C</text>
<text x="4948.3" y="4016.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-62.4,4948.3,4016.8)" class="sequence" id="seq_Cysteine_261">C</text>
<text x="3930.1" y="4953.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-25.5,3930.1,4953.5)" class="sequence" id="seq_Cysteine_344">C</text>
<text x="3666.8" y="5058.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-18.0,3666.8,5058.3)" class="sequence" id="seq_Cysteine_361">C</text>
<text x="1535.1" y="4592.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(42.6,1535.1,4592.3)" class="sequence" id="seq_Cysteine_498">C</text>
<text x="1183.5" y="4208.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(56.4,1183.5,4208.2)" class="sequence" id="seq_Cysteine_530">C</text>
<text x="1074.3" y="4038.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(61.7,1074.3,4038.1)" class="sequence" id="seq_Cysteine_542">C</text>
<text x="4363.6" y="1357.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(399.7,4363.6,1357.7)" class="sequence" id="seq_Proline_84">P</text>
<text x="4741.6" y="1691.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(413.1,4741.6,1691.1)" class="sequence" id="seq_Arginine_115">R</text>
<text x="4888.8" y="2005.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(422.2,4888.8,2005.4)" class="sequence" id="seq_Proline_135">P</text>
<text x="4911.3" y="2049.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(423.6,4911.3,2049.3)" id="seq_Proline_138" class="sequence">P</text>
<text x="4979.9" y="2150.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(426.8,4979.9,2150.0)" id="seq_Proline_146" class="sequence">P</text>
<text x="5064.7" y="2384.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(433.4,5064.7,2384.1)" id="seq_Arginine_161" class="sequence">R</text>
<text x="5082.0" y="2528.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(437.2,5082.0,2528.7)" id="seq_Arginine_169" class="sequence">R</text>
<text x="5122.9" y="2643.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(440.5,5122.9,2643.1)" id="seq_Arginine_177" class="sequence">R</text>
<text x="5147.3" y="2656.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(440.9,5147.3,2656.0)" class="sequence" id="seq_Proline_178">P</text>
<text x="5155.9" y="2890.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(447.1,5155.9,2890.1)" class="sequence" id="seq_Arginine_192">R</text>
<text x="5159.2" y="3102.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-87.3,5159.2,3102.0)" class="sequence" id="seq_Arginine_204">R</text>
<text x="5178.4" y="3345.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-81.0,5178.4,3345.3)" class="sequence" id="seq_Arginine_219">R</text>
<text x="5109.8" y="3608.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-73.9,5109.8,3608.0)" id="seq_Proline_235" class="sequence">P</text>
<text x="5020.6" y="3768.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-69.2,5020.6,3768.1)" class="sequence" id="seq_Arginine_245">R</text>
<text x="4969.4" y="3891.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-65.7,4969.4,3891.2)" id="seq_Proline_253" class="sequence">P</text>
<text x="4965.9" y="3968.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-63.8,4965.9,3968.8)" class="sequence" id="seq_Proline_258">P</text>
<text x="4916.6" y="4038.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-61.6,4916.6,4038.1)" id="seq_Proline_263" class="sequence">P</text>
<text x="4836.0" y="4185.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-57.1,4836.0,4185.9)" class="sequence" id="seq_Arginine_273">R</text>
<text x="4728.9" y="4337.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-52.3,4728.9,4337.1)" id="seq_Proline_284" class="sequence">P</text>
<text x="4676.1" y="4402.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-50.1,4676.1,4402.7)" class="sequence" id="seq_Proline_289">P</text>
<text x="4451.7" y="4601.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-42.2,4451.7,4601.6)" id="seq_Arginine_306" class="sequence">R</text>
<text x="4279.3" y="4764.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-35.9,4279.3,4764.7)" id="seq_Proline_321" class="sequence">P</text>
<text x="4047.8" y="4890.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-29.0,4047.8,4890.8)" class="sequence" id="seq_Proline_336">P</text>
<text x="3899.0" y="4965.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-24.6,3899.0,4965.8)" id="seq_Proline_346" class="sequence">P</text>
<text x="3747.2" y="5048.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-20.0,3747.2,5048.6)" class="sequence" id="seq_Arginine_357">R</text>
<text x="3208.3" y="5151.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-5.5,3208.3,5151.6)" class="sequence" id="seq_Proline_389">P</text>
<text x="3158.6" y="5191.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-4.1,3158.6,5191.9)" class="sequence" id="seq_Arginine_393">R</text>
<text x="2777.8" y="5150.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(5.9,2777.8,5150.2)" id="seq_Proline_415" class="sequence">P</text>
<text x="2594.5" y="5123.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(10.8,2594.5,5123.3)" class="sequence" id="seq_Proline_426">P</text>
<text x="2193.1" y="5050.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(21.5,2193.1,5050.6)" id="seq_Proline_451" class="sequence">P</text>
<text x="2060.0" y="4946.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(25.8,2060.0,4946.6)" id="seq_Arginine_460" class="sequence">R</text>
<text x="1933.0" y="4891.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(29.4,1933.0,4891.4)" id="seq_Proline_469" class="sequence">P</text>
<text x="1741.0" y="4786.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(35.2,1741.0,4786.6)" class="sequence" id="seq_Arginine_482">R</text>
<text x="1635.8" y="4702.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(38.7,1635.8,4702.5)" id="seq_Proline_490" class="sequence">P</text>
<text x="1613.1" y="4658.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(39.9,1613.1,4658.1)" id="seq_Proline_492" class="sequence">P</text>
<text x="1513.6" y="4569.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(43.4,1513.6,4569.5)" class="sequence" id="seq_Proline_500">P</text>
<text x="1339.1" y="4428.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(49.3,1339.1,4428.4)" class="sequence" id="seq_Arginine_514">R</text>
<text x="1310.8" y="4348.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(51.4,1310.8,4348.8)" class="sequence" id="seq_Arginine_518">R</text>
<text x="1123.7" y="4073.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(60.2,1123.7,4073.4)" class="sequence" id="seq_Proline_538">P</text>
<text x="959.8" y="3767.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(69.4,959.8,3767.1)" class="sequence" id="seq_Arginine_559">R</text>
<text x="908.1" y="3686.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(71.8,908.1,3686.5)" class="sequence" id="seq_Proline_565">P</text>
<text x="852.1" y="3404.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(79.3,852.1,3404.3)" id="seq_Arginine_582" class="sequence">R</text>
<text x="870.5" y="3371.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(80.1,870.5,3371.5)" id="seq_Proline_583" class="sequence">P</text>
<text x="816.4" y="3273.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(82.9,816.4,3273.0)" class="sequence" id="seq_Proline_590">P</text>
<text x="868.2" y="2889.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-87.0,868.2,2889.6)" class="sequence" id="seq_Proline_612">P</text>
<text x="855.5" y="2753.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-83.4,855.5,2753.2)" id="seq_Arginine_621" class="sequence">R</text>
<text x="937.4" y="2380.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-73.3,937.4,2380.3)" class="sequence" id="seq_Arginine_644">R</text>
<text x="969.2" y="2250.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-69.7,969.2,2250.5)" class="sequence" id="seq_Arginine_652">R</text>
<text x="1105.6" y="1965.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-61.4,1105.6,1965.0)" id="seq_Arginine_671" class="sequence">R</text>
<text x="1140.1" y="1869.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-58.7,1140.1,1869.2)" class="sequence" id="seq_Proline_677">P</text>
<text x="1191.0" y="1866.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-57.9,1191.0,1866.8)" id="seq_Arginine_678" class="sequence">R</text>
<text x="1283.6" y="1730.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-53.5,1283.6,1730.9)" id="seq_Proline_688" class="sequence">P</text>
<text x="1342.0" y="1623.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-50.3,1342.0,1623.9)" class="sequence" id="seq_Proline_696">P</text>
<text x="1335.8" y="1597.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-49.9,1335.8,1597.0)" class="sequence" id="seq_Arginine_697">R</text>
<text x="1448.6" y="1519.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-46.3,1448.6,1519.2)" id="seq_Arginine_705" class="sequence">R</text>
<text x="1476.2" y="1476.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-45.0,1476.2,1476.7)" id="seq_Arginine_708" class="sequence">R</text>
<text x="1499.9" y="1453.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-44.1,1499.9,1453.4)" class="sequence" id="seq_Arginine_710">R</text>
<text x="1557.8" y="1368.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-41.5,1557.8,1368.4)" class="sequence" id="seq_Arginine_716">R</text>
<text x="1732.3" y="1238.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-35.7,1732.3,1238.0)" class="sequence" id="seq_Proline_729">P</text>
<text x="1819.0" y="1221.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-33.6,1819.0,1221.8)" class="sequence" id="seq_Proline_733">P</text>
<text x="1808.9" y="1202.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-33.5,1808.9,1202.1)" class="sequence" id="seq_Proline_734">P</text>
<text x="1848.6" y="1171.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-32.2,1848.6,1171.7)" id="seq_Proline_737" class="sequence">P</text>
<text x="1886.7" y="1178.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-31.4,1886.7,1178.7)" class="sequence" id="seq_Proline_738">P</text>
<text x="2283.3" y="963.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-19.4,2283.3,963.8)" class="sequence" id="seq_Arginine_766">R</text>
<text x="2333.8" y="972.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-18.2,2333.8,972.0)" id="seq_Arginine_768" class="sequence">R</text>
<text x="2426.2" y="919.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(203,24,29);" transform="rotate(-15.4,2426.2,919.0)" id="seq_Arginine_775" class="sequence">R</text>
<text x="2502.2" y="879.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-13.2,2502.2,879.0)" class="sequence" id="seq_Proline_780">P</text>
<text x="2719.5" y="859.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-7.5,2719.5,859.6)" class="sequence" id="seq_Proline_793">P</text>
<text x="3119.4" y="838.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(363.2,3119.4,838.6)" id="seq_Serine_2" class="sequence">S</text>
<text x="3148.2" y="870.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(364.0,3148.2,870.5)" id="seq_Serine_3" class="sequence">S</text>
<text x="3152.0" y="850.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(364.0,3152.0,850.7)" class="sequence" id="seq_Serine_4">S</text>
<text x="3170.2" y="832.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(364.5,3170.2,832.0)" id="seq_Serine_5" class="sequence">S</text>
<text x="3260.8" y="881.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(367.0,3260.8,881.3)" id="seq_Serine_10" class="sequence">S</text>
<text x="3411.0" y="905.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(371.1,3411.0,905.3)" class="sequence" id="seq_Serine_19">S</text>
<text x="3445.8" y="902.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(372.0,3445.8,902.2)" id="seq_Glutamic-Acid_22" class="sequence">E</text>
<text x="3466.2" y="886.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(372.4,3466.2,886.2)" class="sequence" id="seq_Glutamic-Acid_23">E</text>
<text x="3657.7" y="944.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(377.7,3657.7,944.0)" class="sequence" id="seq_Glutamic-Acid_35">E</text>
<text x="3693.0" y="981.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(378.9,3693.0,981.0)" id="seq_Glutamic-Acid_37" class="sequence">E</text>
<text x="3783.9" y="986.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(381.3,3783.9,986.6)" class="sequence" id="seq_Serine_43">S</text>
<text x="3802.7" y="1022.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(382.1,3802.7,1022.0)" class="sequence" id="seq_Serine_44">S</text>
<text x="3846.4" y="1040.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(383.4,3846.4,1040.3)" class="sequence" id="seq_Serine_47">S</text>
<text x="3985.0" y="1068.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(387.0,3985.0,1068.0)" id="seq_Glutamic-Acid_56" class="sequence">E</text>
<text x="3994.8" y="1111.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(387.8,3994.8,1111.3)" id="seq_Glutamic-Acid_57" class="sequence">E</text>
<text x="4180.5" y="1221.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(393.6,4180.5,1221.4)" class="sequence" id="seq_Serine_70">S</text>
<text x="4246.5" y="1267.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(395.7,4246.5,1267.1)" class="sequence" id="seq_Glutamic-Acid_75">E</text>
<text x="4276.3" y="1288.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(396.7,4276.3,1288.9)" class="sequence" id="seq_Serine_77">S</text>
<text x="4402.7" y="1391.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(401.1,4402.7,1391.0)" class="sequence" id="seq_Glutamic-Acid_87">E</text>
<text x="4611.8" y="1600.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(409.0,4611.8,1600.4)" class="sequence" id="seq_Serine_105">S</text>
<text x="4628.5" y="1589.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(409.1,4628.5,1589.2)" id="seq_Serine_106" class="sequence">S</text>
<text x="4659.2" y="1628.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(410.4,4659.2,1628.5)" id="seq_Serine_109" class="sequence">S</text>
<text x="4685.2" y="1628.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(410.9,4685.2,1628.7)" id="seq_Glutamic-Acid_110" class="sequence">E</text>
<text x="4695.0" y="1702.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(412.6,4695.0,1702.4)" class="sequence" id="seq_Serine_113">S</text>
<text x="4798.8" y="1850.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(417.4,4798.8,1850.7)" id="seq_Serine_124" class="sequence">S</text>
<text x="4855.3" y="1877.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(418.8,4855.3,1877.1)" id="seq_Serine_128" class="sequence">S</text>
<text x="4926.6" y="2080.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(424.5,4926.6,2080.7)" class="sequence" id="seq_Glutamic-Acid_140">E</text>
<text x="4959.8" y="2153.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(426.6,4959.8,2153.8)" id="seq_Glutamic-Acid_145" class="sequence">E</text>
<text x="4990.9" y="2229.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(428.9,4990.9,2229.9)" id="seq_Glutamic-Acid_150" class="sequence">E</text>
<text x="5019.1" y="2307.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(431.1,5019.1,2307.2)" id="seq_Serine_155" class="sequence">S</text>
<text x="5044.3" y="2385.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(433.3,5044.3,2385.5)" class="sequence" id="seq_Glutamic-Acid_160">E</text>
<text x="5070.5" y="2480.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(435.9,5070.5,2480.7)" class="sequence" id="seq_Glutamic-Acid_166">E</text>
<text x="5091.0" y="2480.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(436.0,5091.0,2480.2)" class="sequence" id="seq_Serine_167">S</text>
<text x="5104.4" y="2528.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(437.4,5104.4,2528.3)" id="seq_Serine_170" class="sequence">S</text>
<text x="5089.4" y="2562.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(438.2,5089.4,2562.8)" id="seq_Glutamic-Acid_171" class="sequence">E</text>
<text x="5116.6" y="2723.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(442.5,5116.6,2723.1)" class="sequence" id="seq_Glutamic-Acid_181">E</text>
<text x="5137.0" y="2724.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(442.7,5137.0,2724.9)" id="seq_Glutamic-Acid_182" class="sequence">E</text>
<text x="5129.7" y="2854.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(446.1,5129.7,2854.0)" class="sequence" id="seq_Glutamic-Acid_189">E</text>
<text x="5134.6" y="2985.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(449.6,5134.6,2985.6)" id="seq_Glutamic-Acid_197" class="sequence">E</text>
<text x="5179.9" y="3158.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-85.9,5179.9,3158.1)" class="sequence" id="seq_Glutamic-Acid_208">E</text>
<text x="5163.2" y="3325.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-81.4,5163.2,3325.9)" class="sequence" id="seq_Serine_218">S</text>
<text x="5147.8" y="3425.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-78.8,5147.8,3425.9)" id="seq_Glutamic-Acid_224" class="sequence">E</text>
<text x="5133.5" y="3474.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-77.5,5133.5,3474.6)" class="sequence" id="seq_Glutamic-Acid_227">E</text>
<text x="5091.6" y="3546.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-75.4,5091.6,3546.0)" id="seq_Glutamic-Acid_231" class="sequence">E</text>
<text x="5109.8" y="3555.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-75.3,5109.8,3555.4)" id="seq_Glutamic-Acid_232" class="sequence">E</text>
<text x="5059.1" y="3658.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-72.3,5059.1,3658.0)" class="sequence" id="seq_Glutamic-Acid_238">E</text>
<text x="4989.4" y="3905.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-65.5,4989.4,3905.2)" id="seq_Serine_254" class="sequence">S</text>
<text x="4957.1" y="3945.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-64.2,4957.1,3945.8)" class="sequence" id="seq_Serine_257">S</text>
<text x="4743.2" y="4281.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-53.7,4743.2,4281.7)" id="seq_Serine_280" class="sequence">S</text>
<text x="4403.2" y="4644.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-40.5,4403.2,4644.3)" id="seq_Glutamic-Acid_310" class="sequence">E</text>
<text x="4377.7" y="4665.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-39.6,4377.7,4665.7)" class="sequence" id="seq_Glutamic-Acid_312">E</text>
<text x="4313.7" y="4719.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-37.4,4313.7,4719.2)" class="sequence" id="seq_Serine_317">S</text>
<text x="4148.2" y="4831.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-32.1,4148.2,4831.5)" class="sequence" id="seq_Glutamic-Acid_329">E</text>
<text x="4119.1" y="4851.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-31.1,4119.1,4851.7)" class="sequence" id="seq_Serine_331">S</text>
<text x="3440.8" y="5116.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-11.8,3440.8,5116.2)" class="sequence" id="seq_Glutamic-Acid_375">E</text>
<text x="3073.6" y="5184.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-1.9,3073.6,5184.4)" id="seq_Glutamic-Acid_398" class="sequence">E</text>
<text x="2994.0" y="5161.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(0.2,2994.0,5161.6)" class="sequence" id="seq_Glutamic-Acid_402">E</text>
<text x="2938.9" y="5184.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(1.6,2938.9,5184.8)" class="sequence" id="seq_Glutamic-Acid_406">E</text>
<text x="2887.4" y="5200.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(2.9,2887.4,5200.8)" id="seq_Serine_409" class="sequence">S</text>
<text x="2855.0" y="5176.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(3.8,2855.0,5176.8)" class="sequence" id="seq_Serine_411">S</text>
<text x="2692.8" y="5141.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(8.2,2692.8,5141.7)" class="sequence" id="seq_Serine_420">S</text>
<text x="2618.2" y="5166.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(10.0,2618.2,5166.3)" id="seq_Serine_425" class="sequence">S</text>
<text x="2529.2" y="5109.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(12.6,2529.2,5109.8)" class="sequence" id="seq_Glutamic-Acid_430">E</text>
<text x="2482.5" y="5098.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(13.9,2482.5,5098.8)" id="seq_Glutamic-Acid_433" class="sequence">E</text>
<text x="2450.2" y="5090.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(14.7,2450.2,5090.6)" class="sequence" id="seq_Glutamic-Acid_435">E</text>
<text x="2105.3" y="4967.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(24.5,2105.3,4967.8)" id="seq_Glutamic-Acid_457" class="sequence">E</text>
<text x="1955.6" y="4920.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(28.5,1955.6,4920.0)" class="sequence" id="seq_Glutamic-Acid_467">E</text>
<text x="1786.0" y="4788.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(34.2,1786.0,4788.5)" id="seq_Glutamic-Acid_479" class="sequence">E</text>
<text x="1731.4" y="4750.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(35.9,1731.4,4750.3)" class="sequence" id="seq_Glutamic-Acid_483">E</text>
<text x="1651.8" y="4689.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(38.6,1651.8,4689.7)" id="seq_Glutamic-Acid_489" class="sequence">E</text>
<text x="1575.2" y="4625.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(41.2,1575.2,4625.6)" class="sequence" id="seq_Glutamic-Acid_495">E</text>
<text x="1486.7" y="4546.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(44.4,1486.7,4546.4)" class="sequence" id="seq_Serine_502">S</text>
<text x="1428.2" y="4486.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(46.6,1428.2,4486.9)" id="seq_Serine_507" class="sequence">S</text>
<text x="1374.8" y="4464.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(48.0,1374.8,4464.4)" class="sequence" id="seq_Serine_511">S</text>
<text x="1220.2" y="4226.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(55.4,1220.2,4226.8)" class="sequence" id="seq_Glutamic-Acid_527">E</text>
<text x="1126.1" y="4125.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(59.0,1126.1,4125.0)" class="sequence" id="seq_Glutamic-Acid_536">E</text>
<text x="1063.3" y="3986.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(63.0,1063.3,3986.9)" id="seq_Serine_545" class="sequence">S</text>
<text x="1051.1" y="3939.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(64.3,1051.1,3939.8)" class="sequence" id="seq_Serine_547">S</text>
<text x="1039.5" y="3910.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(65.1,1039.5,3910.6)" class="sequence" id="seq_Glutamic-Acid_549">E</text>
<text x="945.8" y="3679.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(71.7,945.8,3679.4)" id="seq_Serine_563" class="sequence">S</text>
<text x="929.2" y="3686.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(71.7,929.2,3686.6)" class="sequence" id="seq_Glutamic-Acid_564">E</text>
<text x="899.8" y="3583.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(74.5,899.8,3583.2)" class="sequence" id="seq_Glutamic-Acid_571">E</text>
<text x="838.4" y="3287.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(82.4,838.4,3287.2)" id="seq_Glutamic-Acid_589" class="sequence">E</text>
<text x="837.0" y="3054.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(88.5,837.0,3054.8)" id="seq_Serine_602" class="sequence">S</text>
<text x="865.5" y="2973.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-89.3,865.5,2973.8)" class="sequence" id="seq_Serine_607">S</text>
<text x="832.9" y="2918.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-87.9,832.9,2918.7)" id="seq_Serine_611" class="sequence">S</text>
<text x="874.2" y="2805.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-84.8,874.2,2805.5)" class="sequence" id="seq_Serine_617">S</text>
<text x="873.4" y="2722.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-82.6,873.4,2722.0)" id="seq_Serine_623" class="sequence">S</text>
<text x="892.5" y="2660.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-80.9,892.5,2660.6)" class="sequence" id="seq_Serine_626">S</text>
<text x="917.0" y="2533.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-77.4,917.0,2533.3)" class="sequence" id="seq_Glutamic-Acid_634">E</text>
<text x="910.3" y="2459.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-75.5,910.3,2459.0)" class="sequence" id="seq_Glutamic-Acid_639">E</text>
<text x="964.0" y="2358.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-72.5,964.0,2358.5)" class="sequence" id="seq_Serine_645">S</text>
<text x="946.3" y="2348.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-72.4,946.3,2348.2)" id="seq_Serine_646" class="sequence">S</text>
<text x="1102.4" y="2022.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-62.7,1102.4,2022.3)" id="seq_Glutamic-Acid_667" class="sequence">E</text>
<text x="1085.8" y="2011.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-62.7,1085.8,2011.0)" class="sequence" id="seq_Glutamic-Acid_668">E</text>
<text x="1183.6" y="1837.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-57.4,1183.6,1837.3)" id="seq_Serine_680" class="sequence">S</text>
<text x="1297.2" y="1673.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-52.1,1297.2,1673.2)" class="sequence" id="seq_Serine_692">S</text>
<text x="1371.2" y="1583.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-49.0,1371.2,1583.3)" class="sequence" id="seq_Glutamic-Acid_699">E</text>
<text x="1419.2" y="1565.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-47.8,1419.2,1565.5)" class="sequence" id="seq_Glutamic-Acid_701">E</text>
<text x="1488.6" y="1492.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-45.1,1488.6,1492.5)" id="seq_Serine_707" class="sequence">S</text>
<text x="1510.6" y="1470.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-44.2,1510.6,1470.8)" class="sequence" id="seq_Serine_709">S</text>
<text x="1633.7" y="1328.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-39.3,1633.7,1328.8)" id="seq_Serine_721" class="sequence">S</text>
<text x="1663.4" y="1312.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-38.4,1663.4,1312.6)" id="seq_Glutamic-Acid_723" class="sequence">E</text>
<text x="1914.9" y="1161.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-30.6,1914.9,1161.7)" id="seq_Serine_740" class="sequence">S</text>
<text x="2462.0" y="934.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-14.6,2462.0,934.3)" id="seq_Serine_776" class="sequence">S</text>
<text x="2491.9" y="926.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-13.8,2491.9,926.7)" id="seq_Glutamic-Acid_778" class="sequence">E</text>
<text x="2574.2" y="908.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-11.5,2574.2,908.3)" id="seq_Serine_783" class="sequence">S</text>
<text x="2623.3" y="888.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-10.1,2623.3,888.7)" id="seq_Serine_787" class="sequence">S</text>
<text x="2670.1" y="866.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(33,113,181);" transform="rotate(-8.8,2670.1,866.7)" id="seq_Glutamic-Acid_790" class="sequence">E</text>
<text x="2901.8" y="843.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(255,0,255);" transform="rotate(-2.6,2901.8,843.6)" class="sequence" id="seq_Serine_804">S</text>
<text x="3551.4" y="937.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(375.0,3551.4,937.8)" id="seq_Phenylalanine_28" class="sequence">F</text>
<text x="3609.9" y="929.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(376.4,3609.9,929.3)" id="seq_Phenylalanine_32" class="sequence">F</text>
<text x="3734.4" y="976.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(379.9,3734.4,976.5)" class="sequence" id="seq_Phenylalanine_40">F</text>
<text x="4206.1" y="1238.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(394.4,4206.1,1238.7)" class="sequence" id="seq_Phenylalanine_72">F</text>
<text x="5122.0" y="3523.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-76.1,5122.0,3523.8)" id="seq_Phenylalanine_230" class="sequence">F</text>
<text x="4800.0" y="4197.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-56.4,4800.0,4197.0)" id="seq_Phenylalanine_274" class="sequence">F</text>
<text x="4692.2" y="4345.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-51.5,4692.2,4345.1)" id="seq_Phenylalanine_285" class="sequence">F</text>
<text x="4452.1" y="4630.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-41.7,4452.1,4630.8)" id="seq_Phenylalanine_308" class="sequence">F</text>
<text x="4351.9" y="4686.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-38.7,4351.9,4686.8)" class="sequence" id="seq_Phenylalanine_314">F</text>
<text x="4360.2" y="4704.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-38.6,4360.2,4704.5)" class="sequence" id="seq_Phenylalanine_315">F</text>
<text x="4174.6" y="4814.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-32.9,4174.6,4814.7)" class="sequence" id="seq_Phenylalanine_327">F</text>
<text x="3745.0" y="5029.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-20.2,3745.0,5029.2)" id="seq_Phenylalanine_356" class="sequence">F</text>
<text x="3538.2" y="5093.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-14.4,3538.2,5093.6)" class="sequence" id="seq_Phenylalanine_369">F</text>
<text x="3207.9" y="5173.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-5.5,3207.9,5173.7)" id="seq_Phenylalanine_390" class="sequence">F</text>
<text x="3025.3" y="5161.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-0.7,3025.3,5161.5)" class="sequence" id="seq_Phenylalanine_400">F</text>
<text x="2563.8" y="5117.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(11.6,2563.8,5117.2)" id="seq_Phenylalanine_428" class="sequence">F</text>
<text x="2402.0" y="5077.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(16.1,2402.0,5077.3)" id="seq_Phenylalanine_438" class="sequence">F</text>
<text x="2181.8" y="5000.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(22.2,2181.8,5000.8)" id="seq_Phenylalanine_452" class="sequence">F</text>
<text x="2000.2" y="4943.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(27.2,2000.2,4943.6)" id="seq_Phenylalanine_464" class="sequence">F</text>
<text x="1447.7" y="4558.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(44.9,1447.7,4558.4)" id="seq_Phenylalanine_504" class="sequence">F</text>
<text x="1373.6" y="4423.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(48.8,1373.6,4423.9)" class="sequence" id="seq_Phenylalanine_512">F</text>
<text x="1258.9" y="4281.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(53.7,1258.9,4281.1)" class="sequence" id="seq_Phenylalanine_523">F</text>
<text x="1239.3" y="4254.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(54.5,1239.3,4254.1)" id="seq_Phenylalanine_525" class="sequence">F</text>
<text x="994.9" y="3807.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(68.1,994.9,3807.7)" id="seq_Phenylalanine_555" class="sequence">F</text>
<text x="857.8" y="3289.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(82.3,857.8,3289.2)" id="seq_Phenylalanine_588" class="sequence">F</text>
<text x="833.3" y="3237.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(83.8,833.3,3237.1)" id="seq_Phenylalanine_592" class="sequence">F</text>
<text x="819.0" y="3052.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(88.6,819.0,3052.7)" class="sequence" id="seq_Phenylalanine_603">F</text>
<text x="954.4" y="2390.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-73.4,954.4,2390.0)" id="seq_Phenylalanine_643" class="sequence">F</text>
<text x="992.7" y="2206.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-68.4,992.7,2206.0)" class="sequence" id="seq_Phenylalanine_655">F</text>
<text x="1077.7" y="2049.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-63.7,1077.7,2049.1)" class="sequence" id="seq_Phenylalanine_665">F</text>
<text x="1210.4" y="1818.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-56.6,1210.4,1818.1)" id="seq_Phenylalanine_681" class="sequence">F</text>
<text x="1236.0" y="1798.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-55.7,1236.0,1798.0)" class="sequence" id="seq_Phenylalanine_683">F</text>
<text x="1222.8" y="1783.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-55.6,1222.8,1783.5)" class="sequence" id="seq_Phenylalanine_684">F</text>
<text x="1557.9" y="1393.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-41.9,1557.9,1393.7)" class="sequence" id="seq_Phenylalanine_715">F</text>
<text x="1664.1" y="1286.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-37.9,1664.1,1286.6)" class="sequence" id="seq_Phenylalanine_724">F</text>
<text x="2001.0" y="1113.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-27.9,2001.0,1113.5)" id="seq_Phenylalanine_746" class="sequence">F</text>
<text x="2225.9" y="999.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-21.2,2225.9,999.9)" class="sequence" id="seq_Phenylalanine_762">F</text>
<text x="2767.2" y="878.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-6.3,2767.2,878.1)" id="seq_Phenylalanine_795" class="sequence">F</text>
<text x="2933.3" y="866.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(35,139,69);" transform="rotate(-1.8,2933.3,866.4)" id="seq_Phenylalanine_805" class="sequence">F</text>
<text x="3211.8" y="875.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(365.7,3211.8,875.9)" id="seq_Leucine_7" class="sequence">L</text>
<text x="3218.0" y="858.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(365.8,3218.0,858.4)" id="seq_Leucine_8" class="sequence">L</text>
<text x="3236.5" y="842.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(366.3,3236.5,842.3)" class="sequence" id="seq_Leucine_9">L</text>
<text x="3267.7" y="862.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(367.1,3267.7,862.0)" id="seq_Leucine_11" class="sequence">L</text>
<text x="3560.6" y="920.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(375.1,3560.6,920.6)" id="seq_Leucine_29" class="sequence">L</text>
<text x="3724.0" y="991.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(379.8,3724.0,991.9)" id="seq_Leucine_39" class="sequence">L</text>
<text x="3812.5" y="1004.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(382.2,3812.5,1004.4)" id="seq_Leucine_45" class="sequence">L</text>
<text x="4220.5" y="1225.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(394.5,4220.5,1225.6)" id="seq_Leucine_73" class="sequence">L</text>
<text x="4299.3" y="1306.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(397.5,4299.3,1306.3)" class="sequence" id="seq_Leucine_79">L</text>
<text x="4381.1" y="1343.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(399.8,4381.1,1343.6)" id="seq_Leucine_85" class="sequence">L</text>
<text x="4457.6" y="1407.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(402.5,4457.6,1407.8)" class="sequence" id="seq_Leucine_91">L</text>
<text x="4497.8" y="1479.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(404.6,4497.8,1479.1)" class="sequence" id="seq_Leucine_95">L</text>
<text x="4522.5" y="1503.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(405.5,4522.5,1503.8)" class="sequence" id="seq_Leucine_97">L</text>
<text x="4555.3" y="1537.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(406.8,4555.3,1537.9)" id="seq_Leucine_100" class="sequence">L</text>
<text x="4642.5" y="1636.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(410.3,4642.5,1636.5)" id="seq_Leucine_108" class="sequence">L</text>
<text x="4723.4" y="1740.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(413.8,4723.4,1740.4)" class="sequence" id="seq_Leucine_116">L</text>
<text x="4762.8" y="1778.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(415.3,4762.8,1778.5)" class="sequence" id="seq_Leucine_120">L</text>
<text x="4940.5" y="2110.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(425.4,4940.5,2110.5)" class="sequence" id="seq_Leucine_142">L</text>
<text x="4957.9" y="2105.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(425.4,4957.9,2105.3)" id="seq_Leucine_143" class="sequence">L</text>
<text x="4981.2" y="2113.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(425.9,4981.2,2113.0)" id="seq_Leucine_144" class="sequence">L</text>
<text x="4979.5" y="2201.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(428.0,4979.5,2201.2)" id="seq_Leucine_148" class="sequence">L</text>
<text x="5039.5" y="2305.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(431.2,5039.5,2305.0)" class="sequence" id="seq_Leucine_156">L</text>
<text x="5053.5" y="2417.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(434.2,5053.5,2417.1)" id="seq_Leucine_162" class="sequence">L</text>
<text x="5104.7" y="2643.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(440.4,5104.7,2643.7)" id="seq_Leucine_176" class="sequence">L</text>
<text x="5112.1" y="2690.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(441.7,5112.1,2690.5)" class="sequence" id="seq_Leucine_179">L</text>
<text x="5125.7" y="2804.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(444.8,5125.7,2804.8)" class="sequence" id="seq_Leucine_186">L</text>
<text x="5124.0" y="3401.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-79.3,5124.0,3401.7)" id="seq_Leucine_222" class="sequence">L</text>
<text x="5069.0" y="3626.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-73.2,5069.0,3626.2)" class="sequence" id="seq_Leucine_236">L</text>
<text x="5048.7" y="3689.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-71.4,5048.7,3689.7)" id="seq_Leucine_240" class="sequence">L</text>
<text x="5002.3" y="3814.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-67.9,5002.3,3814.6)" class="sequence" id="seq_Leucine_248">L</text>
<text x="4902.9" y="4025.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-61.7,4902.9,4025.6)" class="sequence" id="seq_Leucine_262">L</text>
<text x="4897.3" y="4085.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-60.2,4897.3,4085.1)" id="seq_Leucine_266" class="sequence">L</text>
<text x="4861.9" y="4098.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-59.5,4861.9,4098.1)" class="sequence" id="seq_Leucine_267">L</text>
<text x="4762.3" y="4251.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-54.6,4762.3,4251.9)" class="sequence" id="seq_Leucine_278">L</text>
<text x="4756.2" y="4294.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-53.6,4756.2,4294.4)" class="sequence" id="seq_Leucine_281">L</text>
<text x="4272.4" y="4747.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-36.1,4272.4,4747.5)" id="seq_Leucine_320" class="sequence">L</text>
<text x="4091.2" y="4866.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-30.3,4091.2,4866.0)" class="sequence" id="seq_Leucine_333">L</text>
<text x="3822.6" y="4999.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-22.4,3822.6,4999.0)" class="sequence" id="seq_Leucine_351">L</text>
<text x="3712.6" y="5051.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-19.2,3712.6,5051.4)" id="seq_Leucine_359" class="sequence">L</text>
<text x="3538.5" y="5113.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-14.3,3538.5,5113.1)" id="seq_Leucine_370" class="sequence">L</text>
<text x="3177.1" y="5154.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-4.7,3177.1,5154.4)" class="sequence" id="seq_Leucine_391">L</text>
<text x="3174.1" y="5172.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-4.6,3174.1,5172.7)" class="sequence" id="seq_Leucine_392">L</text>
<text x="2860.8" y="5157.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(3.7,2860.8,5157.2)" id="seq_Leucine_410" class="sequence">L</text>
<text x="2728.1" y="5144.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(7.2,2728.1,5144.5)" class="sequence" id="seq_Leucine_418">L</text>
<text x="2643.7" y="5132.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(9.5,2643.7,5132.1)" class="sequence" id="seq_Leucine_423">L</text>
<text x="2638.3" y="5149.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(9.6,2638.3,5149.4)" class="sequence" id="seq_Leucine_424">L</text>
<text x="2392.4" y="5094.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(16.2,2392.4,5094.3)" id="seq_Leucine_439" class="sequence">L</text>
<text x="2370.1" y="5067.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(16.9,2370.1,5067.8)" id="seq_Leucine_440" class="sequence">L</text>
<text x="2310.6" y="5074.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(18.4,2310.6,5074.1)" id="seq_Leucine_444" class="sequence">L</text>
<text x="2215.4" y="5040.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(21.0,2215.4,5040.0)" id="seq_Leucine_450" class="sequence">L</text>
<text x="2119.5" y="5007.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(23.7,2119.5,5007.0)" id="seq_Leucine_456" class="sequence">L</text>
<text x="1472.3" y="4557.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(44.4,1472.3,4557.5)" class="sequence" id="seq_Leucine_503">L</text>
<text x="1290.2" y="4322.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(52.3,1290.2,4322.6)" id="seq_Leucine_520" class="sequence">L</text>
<text x="1202.6" y="4200.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(56.3,1202.6,4200.9)" class="sequence" id="seq_Leucine_529">L</text>
<text x="1102.3" y="4080.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(60.3,1102.3,4080.4)" id="seq_Leucine_539" class="sequence">L</text>
<text x="981.9" y="3844.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(67.3,981.9,3844.4)" id="seq_Leucine_554" class="sequence">L</text>
<text x="976.8" y="3761.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(69.4,976.8,3761.2)" id="seq_Leucine_558" class="sequence">L</text>
<text x="966.7" y="3733.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(70.2,966.7,3733.7)" class="sequence" id="seq_Leucine_560">L</text>
<text x="908.1" y="3633.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(73.2,908.1,3633.3)" id="seq_Leucine_568" class="sequence">L</text>
<text x="918.4" y="3582.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(74.4,918.4,3582.7)" class="sequence" id="seq_Leucine_570">L</text>
<text x="848.1" y="3370.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(80.2,848.1,3370.8)" id="seq_Leucine_584" class="sequence">L</text>
<text x="865.0" y="3338.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(81.0,865.0,3338.7)" id="seq_Leucine_585" class="sequence">L</text>
<text x="851.7" y="3239.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(83.6,851.7,3239.6)" id="seq_Leucine_591" class="sequence">L</text>
<text x="845.3" y="3173.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(85.4,845.3,3173.2)" id="seq_Leucine_595" class="sequence">L</text>
<text x="855.8" y="2702.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-82.1,855.8,2702.9)" class="sequence" id="seq_Leucine_624">L</text>
<text x="897.6" y="2630.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-80.0,897.6,2630.1)" id="seq_Leucine_628" class="sequence">L</text>
<text x="923.3" y="2410.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-74.2,923.3,2410.8)" class="sequence" id="seq_Leucine_642">L</text>
<text x="1025.7" y="2188.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-67.7,1025.7,2188.4)" class="sequence" id="seq_Leucine_656">L</text>
<text x="1047.2" y="2066.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-64.4,1047.2,2066.1)" id="seq_Leucine_664" class="sequence">L</text>
<text x="1165.2" y="1909.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-59.3,1165.2,1909.0)" class="sequence" id="seq_Leucine_675">L</text>
<text x="1607.7" y="1381.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-40.7,1607.7,1381.9)" id="seq_Leucine_717" class="sequence">L</text>
<text x="1672.6" y="1328.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-38.4,1672.6,1328.2)" class="sequence" id="seq_Leucine_722">L</text>
<text x="1710.0" y="1299.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-37.2,1710.0,1299.2)" class="sequence" id="seq_Leucine_725">L</text>
<text x="1766.5" y="1228.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-34.8,1766.5,1228.5)" id="seq_Leucine_731" class="sequence">L</text>
<text x="1957.7" y="1137.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-29.2,1957.7,1137.1)" class="sequence" id="seq_Leucine_743">L</text>
<text x="2191.4" y="1002.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-22.0,2191.4,1002.8)" class="sequence" id="seq_Leucine_760">L</text>
<text x="3439.3" y="911.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(371.9,3439.3,911.0)" id="seq_Isoleucine_21" class="sequence">I</text>
<text x="3950.9" y="1088.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(386.5,3950.9,1088.8)" id="seq_Isoleucine_54" class="sequence">I</text>
<text x="4417.8" y="1377.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(401.1,4417.8,1377.5)" class="sequence" id="seq_Isoleucine_88">I</text>
<text x="4752.1" y="1780.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(415.2,4752.1,1780.6)" id="seq_Isoleucine_119" class="sequence">I</text>
<text x="4815.3" y="1876.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(418.3,4815.3,1876.8)" class="sequence" id="seq_Isoleucine_126">I</text>
<text x="5011.2" y="2226.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(429.0,5011.2,2226.9)" class="sequence" id="seq_Isoleucine_151">I</text>
<text x="5141.2" y="3407.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-79.2,5141.2,3407.5)" id="seq_Isoleucine_223" class="sequence">I</text>
<text x="5082.9" y="3578.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-74.5,5082.9,3578.2)" class="sequence" id="seq_Isoleucine_233">I</text>
<text x="4948.3" y="3936.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-64.3,4948.3,3936.5)" class="sequence" id="seq_Isoleucine_256">I</text>
<text x="4926.1" y="3981.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-63.0,4926.1,3981.3)" id="seq_Isoleucine_259" class="sequence">I</text>
<text x="4628.2" y="4421.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-48.9,4628.2,4421.9)" class="sequence" id="seq_Isoleucine_291">I</text>
<text x="4430.3" y="4620.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-41.4,4430.3,4620.8)" id="seq_Isoleucine_307" class="sequence">I</text>
<text x="3713.6" y="5040.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-19.3,3713.6,5040.5)" class="sequence" id="seq_Isoleucine_358">I</text>
<text x="3375.4" y="5128.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-10.0,3375.4,5128.8)" id="seq_Isoleucine_379" class="sequence">I</text>
<text x="2910.7" y="5159.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(2.4,2910.7,5159.8)" class="sequence" id="seq_Isoleucine_407">I</text>
<text x="2687.8" y="5159.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(8.2,2687.8,5159.2)" id="seq_Isoleucine_421" class="sequence">I</text>
<text x="2440.7" y="5108.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(14.9,2440.7,5108.8)" id="seq_Isoleucine_436" class="sequence">I</text>
<text x="2275.1" y="5036.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(19.6,2275.1,5036.5)" class="sequence" id="seq_Isoleucine_446">I</text>
<text x="1941.8" y="4884.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(29.3,1941.8,4884.9)" class="sequence" id="seq_Isoleucine_468">I</text>
<text x="1716.0" y="4763.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(36.1,1716.0,4763.8)" id="seq_Isoleucine_484" class="sequence">I</text>
<text x="1357.7" y="4434.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(48.9,1357.7,4434.6)" id="seq_Isoleucine_513" class="sequence">I</text>
<text x="1076.1" y="3985.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(62.9,1076.1,3985.5)" class="sequence" id="seq_Isoleucine_544">I</text>
<text x="854.4" y="2803.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-84.8,854.4,2803.2)" id="seq_Isoleucine_618" class="sequence">I</text>
<text x="882.8" y="2727.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-82.7,882.8,2727.7)" id="seq_Isoleucine_622" class="sequence">I</text>
<text x="1078.4" y="2070.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-64.2,1078.4,2070.5)" id="seq_Isoleucine_663" class="sequence">I</text>
<text x="1206.2" y="1842.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-57.2,1206.2,1842.8)" id="seq_Isoleucine_679" class="sequence">I</text>
<text x="1344.1" y="1652.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-50.9,1344.1,1652.9)" class="sequence" id="seq_Isoleucine_694">I</text>
<text x="1339.2" y="1643.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-50.8,1339.2,1643.1)" id="seq_Isoleucine_695" class="sequence">I</text>
<text x="1452.8" y="1529.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-46.5,1452.8,1529.3)" id="seq_Isoleucine_704" class="sequence">I</text>
<text x="1534.4" y="1448.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-43.4,1534.4,1448.0)" class="sequence" id="seq_Isoleucine_711">I</text>
<text x="1738.0" y="1278.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-36.2,1738.0,1278.3)" id="seq_Isoleucine_727" class="sequence">I</text>
<text x="1908.6" y="1142.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-30.4,1908.6,1142.2)" class="sequence" id="seq_Isoleucine_741">I</text>
<text x="1952.8" y="1119.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-29.1,1952.8,1119.2)" class="sequence" id="seq_Isoleucine_744">I</text>
<text x="2104.3" y="1062.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-24.8,2104.3,1062.4)" id="seq_Isoleucine_753" class="sequence">I</text>
<text x="2179.2" y="1029.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-22.6,2179.2,1029.5)" id="seq_Isoleucine_757" class="sequence">I</text>
<text x="2191.0" y="1013.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-22.2,2191.0,1013.8)" id="seq_Isoleucine_759" class="sequence">I</text>
<text x="2225.4" y="1010.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-21.3,2225.4,1010.9)" id="seq_Isoleucine_761" class="sequence">I</text>
<text x="2300.3" y="983.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-19.1,2300.3,983.3)" id="seq_Isoleucine_765" class="sequence">I</text>
<text x="2572.6" y="888.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-11.4,2572.6,888.2)" id="seq_Isoleucine_784" class="sequence">I</text>
<text x="2620.7" y="899.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(82,82,82);" transform="rotate(-10.2,2620.7,899.3)" class="sequence" id="seq_Isoleucine_786">I</text>
</g>
<g id="plot2">
<g id="plot2-axis">
</g>
<circle cx='3092.8' cy='1047.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_1" class="scatter"/>
<circle cx='3110.9' cy='992.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_2"/>
<circle cx='3130.0' cy='936.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_3"/>
<circle cx='3137.9' cy='1050.0' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_4" class="scatter"/>
<circle cx='3157.4' cy='995.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_5" class="scatter"/>
<polygon points="3193,941 3182,955 3165,949 3165,931 3183,926" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_6"/>
<circle cx='3183.0' cy='1053.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_7" class="scatter"/>
<circle cx='3203.7' cy='999.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_8" class="scatter"/>
<circle cx='3225.2' cy='945.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_9"/>
<circle cx='3227.9' cy='1058.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_10" class="scatter"/>
<circle cx='3249.9' cy='1004.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_11"/>
<circle cx='3272.7' cy='950.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_12"/>
<circle cx='3272.8' cy='1064.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_13" class="scatter"/>
<circle cx='3296.0' cy='1010.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_14" class="scatter"/>
<circle cx='3320.0' cy='957.7' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_15"/>
<circle cx='3317.5' cy='1071.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_16"/>
<circle cx='3341.9' cy='1018.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_17"/>
<circle cx='3367.1' cy='965.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_18"/>
<circle cx='3362.0' cy='1078.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_19"/>
<circle cx='3387.6' cy='1026.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_20" class="scatter"/>
<circle cx='3414.1' cy='974.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_21" class="scatter"/>
<polygon points="3409,1075 3419,1104 3389,1098" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_22"/>
<polygon points="3435,1023 3446,1052 3416,1047" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_23" class="scatter"/>
<circle cx='3460.8' cy='984.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_24"/>
<circle cx='3450.4' cy='1097.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_25"/>
<polygon points="3481,1034 3491,1063 3461,1057" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_26"/>
<circle cx='3507.3' cy='996.0' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_27" class="scatter"/>
<polygon points="3509,1112 3496,1124 3480,1115 3484,1097 3502,1095" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_28"/>
<circle cx='3523.5' cy='1058.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_29" class="scatter"/>
<polygon points="3557,995 3566,1025 3535,1018" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_30" class="scatter"/>
<polygon points="3541,1108 3550,1137 3520,1130" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_31"/>
<polygon points="3583,1075 3569,1086 3554,1077 3558,1059 3576,1058" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_32" class="scatter"/>
<circle cx='3599.4' cy='1021.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_33"/>
<polygon points="3585,1121 3593,1150 3563,1143" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_34"/>
<polygon points="3616,1072 3624,1102 3594,1093" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_35"/>
<circle cx='3645.0' cy='1036.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_36" class="scatter"/>
<polygon points="3628,1135 3635,1165 3606,1156" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_37"/>
<polygon points="3661,1086 3668,1117 3638,1108" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_38"/>
<circle cx='3690.2' cy='1051.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_39"/>
<polygon points="3682,1167 3667,1178 3652,1167 3658,1150 3676,1150" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_40"/>
<polygon points="3715,1120 3701,1130 3686,1120 3691,1102 3710,1102" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_41"/>
<circle cx='3735.1' cy='1067.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_42"/>
<circle cx='3709.2' cy='1178.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_43" class="scatter"/>
<circle cx='3744.0' cy='1131.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_44" class="scatter"/>
<circle cx='3779.6' cy='1085.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_45"/>
<circle cx='3751.1' cy='1195.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_46"/>
<circle cx='3787.0' cy='1149.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_47"/>
<polygon points="3838,1109 3823,1119 3809,1108 3815,1091 3833,1092" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_48"/>
<circle cx='3792.7' cy='1213.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_49"/>
<polygon points="3844,1174 3829,1183 3815,1172 3821,1155 3840,1156" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_50" class="scatter"/>
<circle cx='3867.3' cy='1123.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_51" class="scatter"/>
<circle cx='3833.8' cy='1231.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_52"/>
<circle cx='3871.7' cy='1187.7' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_53" class="scatter"/>
<circle cx='3910.4' cy='1144.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_54" class="scatter"/>
<circle cx='3874.5' cy='1251.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_55" class="scatter"/>
<polygon points="3919,1196 3922,1227 3894,1214" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_56" class="scatter"/>
<polygon points="3959,1153 3961,1184 3933,1171" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_57"/>
<circle cx='3914.7' cy='1272.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_58"/>
<circle cx='3954.6' cy='1229.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_59"/>
<circle cx='3995.3' cy='1188.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_60" class="scatter"/>
<circle cx='3954.4' cy='1293.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_61" class="scatter"/>
<circle cx='3995.3' cy='1252.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_62" class="scatter"/>
<circle cx='4036.9' cy='1211.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_63" class="scatter"/>
<circle cx='3993.6' cy='1316.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_64"/>
<circle cx='4035.4' cy='1276.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_65" class="scatter"/>
<circle cx='4078.0' cy='1236.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_66"/>
<polygon points="4039,1328 4039,1359 4012,1344" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_67" class="scatter"/>
<polygon points="4082,1289 4082,1320 4055,1304" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_68" class="scatter"/>
<polygon points="4132,1269 4115,1277 4103,1263 4112,1247 4130,1251" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_69"/>
<circle cx='4070.3' cy='1364.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_70"/>
<circle cx='4114.0' cy='1325.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_71"/>
<polygon points="4172,1296 4155,1303 4143,1289 4152,1273 4170,1278" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_72"/>
<circle cx='4107.9' cy='1389.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_73"/>
<polygon points="4160,1341 4158,1372 4132,1355" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_74" class="scatter"/>
<polygon points="4205,1304 4203,1335 4177,1318" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_75"/>
<circle cx='4144.8' cy='1415.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_76" class="scatter"/>
<circle cx='4190.3' cy='1379.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_77"/>
<circle cx='4236.3' cy='1343.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_78" class="scatter"/>
<circle cx='4181.2' cy='1442.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_79"/>
<circle cx='4227.4' cy='1407.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_80" class="scatter"/>
<circle cx='4274.3' cy='1372.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_81"/>
<circle cx='4216.9' cy='1470.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_82"/>
<polygon points="4276,1445 4259,1450 4248,1436 4259,1421 4277,1427" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_83"/>
<circle cx='4311.6' cy='1402.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_84"/>
<circle cx='4251.9' cy='1498.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_85"/>
<circle cx='4299.8' cy='1465.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_86"/>
<polygon points="4357,1422 4352,1453 4328,1434" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_87"/>
<circle cx='4286.3' cy='1527.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_88"/>
<circle cx='4334.9' cy='1495.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_89"/>
<circle cx='4384.1' cy='1464.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_90"/>
<circle cx='4320.0' cy='1558.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_91" class="scatter"/>
<circle cx='4369.3' cy='1527.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_92" class="scatter"/>
<circle cx='4419.2' cy='1496.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_93"/>
<polygon points="4362,1579 4356,1609 4332,1589" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_94"/>
<circle cx='4403.0' cy='1559.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_95"/>
<circle cx='4453.6' cy='1530.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_96" class="scatter"/>
<circle cx='4385.3' cy='1620.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_97"/>
<circle cx='4436.0' cy='1592.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_98"/>
<circle cx='4487.2' cy='1564.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_99" class="scatter"/>
<circle cx='4416.8' cy='1653.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_100" class="scatter"/>
<circle cx='4468.1' cy='1625.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_101"/>
<circle cx='4520.0' cy='1598.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_102" class="scatter"/>
<circle cx='4447.6' cy='1686.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_103" class="scatter"/>
<circle cx='4499.5' cy='1659.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_104" class="scatter"/>
<circle cx='4552.0' cy='1634.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_105"/>
<circle cx='4477.6' cy='1720.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_106"/>
<circle cx='4530.1' cy='1695.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_107"/>
<circle cx='4583.2' cy='1670.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_108" class="scatter"/>
<circle cx='4506.8' cy='1754.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_109"/>
<polygon points="4570,1722 4560,1751 4540,1728" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_110" class="scatter"/>
<polygon points="4624,1699 4614,1728 4593,1705" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_111" class="scatter"/>
<polygon points="4545,1781 4535,1810 4515,1787" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_112" class="scatter"/>
<circle cx='4588.8' cy='1767.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_113" class="scatter"/>
<polygon points="4653,1737 4643,1766 4623,1742" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_114"/>
<polygon points="4573,1817 4562,1846 4543,1822" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_115"/>
<circle cx='4616.9' cy='1804.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_116" class="scatter"/>
<circle cx='4671.5' cy='1783.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_117" class="scatter"/>
<circle cx='4589.5' cy='1862.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_118"/>
<circle cx='4644.1' cy='1841.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_119" class="scatter"/>
<circle cx='4699.2' cy='1822.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_120"/>
<circle cx='4615.4' cy='1899.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_121"/>
<circle cx='4670.5' cy='1880.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_122"/>
<circle cx='4726.0' cy='1862.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_123" class="scatter"/>
<circle cx='4640.4' cy='1936.7' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_124" class="scatter"/>
<circle cx='4695.9' cy='1919.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_125" class="scatter"/>
<circle cx='4751.8' cy='1902.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_126"/>
<polygon points="4673,1988 4655,1987 4650,1970 4665,1959 4679,1971" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_127"/>
<circle cx='4720.5' cy='1958.7' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_128" class="scatter"/>
<circle cx='4776.7' cy='1943.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_129"/>
<circle cx='4687.8' cy='2013.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_130"/>
<polygon points="4755,1992 4741,2019 4724,1993" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_131" class="scatter"/>
<circle cx='4800.7' cy='1984.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_132"/>
<circle cx='4710.2' cy='2052.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_133" class="scatter"/>
<circle cx='4766.8' cy='2039.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_134"/>
<circle cx='4823.7' cy='2026.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_135"/>
<polygon points="4743,2086 4728,2113 4712,2086" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_136"/>
<circle cx='4788.5' cy='2080.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_137"/>
<circle cx='4845.7' cy='2068.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_138"/>
<circle cx='4752.1' cy='2133.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_139"/>
<polygon points="4821,2116 4805,2142 4790,2115" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_140"/>
<circle cx='4866.7' cy='2111.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_141" class="scatter"/>
<circle cx='4771.7' cy='2173.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_142"/>
<circle cx='4829.1' cy='2164.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_143" class="scatter"/>
<circle cx='4886.8' cy='2155.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_144" class="scatter"/>
<polygon points="4802,2209 4785,2235 4771,2207" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_145" class="scatter"/>
<circle cx='4848.0' cy='2206.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_146"/>
<circle cx='4905.8' cy='2199.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_147" class="scatter"/>
<circle cx='4808.0' cy='2256.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_148" class="scatter"/>
<circle cx='4865.8' cy='2249.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_149"/>
<polygon points="4936,2238 4918,2263 4905,2235" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_150"/>
<circle cx='4824.7' cy='2298.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_151" class="scatter"/>
<circle cx='4882.7' cy='2292.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_152" class="scatter"/>
<circle cx='4940.8' cy='2288.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_153"/>
<circle cx='4840.5' cy='2341.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_154"/>
<circle cx='4898.5' cy='2336.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_155" class="scatter"/>
<circle cx='4956.7' cy='2333.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_156"/>
<polygon points="4868,2379 4848,2403 4837,2374" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_157" class="scatter"/>
<polygon points="4919,2395 4901,2390 4900,2372 4918,2366 4929,2380" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_158" class="scatter"/>
<circle cx='4971.6' cy='2378.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_159" class="scatter"/>
<polygon points="4882,2422 4861,2446 4851,2417" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_160"/>
<polygon points="4940,2421 4920,2444 4909,2415" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_161" class="scatter"/>
<circle cx='4985.5' cy='2424.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_162" class="scatter"/>
<polygon points="4887,2485 4869,2479 4869,2461 4886,2455 4897,2470" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_163"/>
<circle cx='4939.9' cy='2469.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_164"/>
<polygon points="5003,2485 4986,2479 4986,2461 5003,2456 5014,2471" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_165"/>
<polygon points="4906,2510 4885,2533 4876,2503" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_166" class="scatter"/>
<circle cx='4951.7' cy='2514.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_167"/>
<polygon points="5014,2532 4997,2525 4998,2507 5015,2502 5025,2517" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_168"/>
<polygon points="4917,2554 4895,2576 4887,2546" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_169"/>
<circle cx='4962.4' cy='2560.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_170" class="scatter"/>
<polygon points="5034,2560 5012,2582 5004,2552" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_171"/>
<circle cx='4913.9' cy='2601.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_172"/>
<circle cx='4972.0' cy='2605.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_173" class="scatter"/>
<polygon points="5043,2607 5021,2628 5014,2598" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_174" class="scatter"/>
<circle cx='4922.6' cy='2646.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_175" class="scatter"/>
<circle cx='4980.6' cy='2651.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_176"/>
<polygon points="5052,2654 5029,2675 5022,2645" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_177"/>
<circle cx='4930.3' cy='2690.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_178"/>
<circle cx='4988.1' cy='2697.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_179"/>
<polygon points="5049,2720 5032,2712 5035,2694 5053,2691 5061,2706" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_180"/>
<polygon points="4950,2733 4926,2753 4921,2723" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_181"/>
<polygon points="5008,2741 4984,2761 4979,2730" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_182" class="scatter"/>
<polygon points="5055,2767 5039,2759 5041,2741 5059,2738 5068,2754" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_183"/>
<circle cx='4942.5' cy='2780.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_184" class="scatter"/>
<circle cx='5000.0' cy='2789.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_185" class="scatter"/>
<circle cx='5057.5' cy='2799.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_186" class="scatter"/>
<polygon points="4960,2824 4936,2842 4932,2812" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_187"/>
<circle cx='5004.3' cy='2835.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_188" class="scatter"/>
<polygon points="5075,2845 5050,2864 5046,2833" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_189" class="scatter"/>
<circle cx='4950.6' cy='2870.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_190" class="scatter"/>
<circle cx='5007.6' cy='2882.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_191" class="scatter"/>
<polygon points="5078,2894 5053,2911 5050,2881" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_192"/>
<circle cx='4953.1' cy='2915.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_193"/>
<circle cx='5009.8' cy='2928.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_194"/>
<polygon points="5080,2942 5054,2959 5052,2928" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_195"/>
<polygon points="4955,2976 4940,2966 4945,2949 4963,2948 4970,2965" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_196"/>
<polygon points="5024,2974 4998,2991 4997,2960" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_197" class="scatter"/>
<polygon points="5081,2990 5055,3006 5053,2976" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_198" class="scatter"/>
<polygon points="4956,3021 4940,3011 4945,2994 4963,2993 4970,3010" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_199" class="scatter"/>
<circle cx='5010.9' cy='3021.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_200"/>
<polygon points="5080,3038 5054,3054 5053,3023" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_201" class="scatter"/>
<polygon points="4954,3067 4940,3056 4945,3039 4963,3038 4969,3056" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_202" class="scatter"/>
<polygon points="5010,3084 4995,3073 5001,3056 5019,3055 5025,3073" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_203" class="scatter"/>
<polygon points="5079,3086 5052,3101 5052,3070" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_204" class="scatter"/>
<circle cx='4952.5' cy='3096.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_205"/>
<polygon points="5021,3115 4994,3130 4995,3099" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_206" class="scatter"/>
<polygon points="5063,3149 5048,3138 5054,3121 5072,3121 5078,3139" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_207"/>
<polygon points="4963,3142 4936,3157 4937,3126" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_208"/>
<circle cx='5004.6' cy='3161.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_209"/>
<circle cx='5059.3' cy='3181.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_210" class="scatter"/>
<circle cx='4946.0' cy='3186.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_211"/>
<circle cx='5000.4' cy='3207.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_212"/>
<polygon points="5068,3230 5040,3243 5042,3213" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_213" class="scatter"/>
<circle cx='4941.1' cy='3231.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_214"/>
<polygon points="4994,3269 4980,3257 4987,3240 5005,3242 5009,3259" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_215" class="scatter"/>
<polygon points="5062,3278 5034,3291 5037,3260" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_216" class="scatter"/>
<polygon points="4934,3292 4920,3280 4927,3263 4946,3265 4949,3282" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_217" class="scatter"/>
<circle cx='4988.6' cy='3299.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_218"/>
<polygon points="5055,3325 5027,3338 5030,3307" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_219"/>
<circle cx='4928.4' cy='3321.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_220"/>
<circle cx='4981.2' cy='3345.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_221"/>
<circle cx='5033.7' cy='3370.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_222"/>
<circle cx='4920.4' cy='3365.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_223"/>
<polygon points="4986,3393 4957,3404 4962,3374" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_224" class="scatter"/>
<polygon points="5038,3420 5009,3431 5014,3400" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_225" class="scatter"/>
<circle cx='4911.5' cy='3409.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_226"/>
<polygon points="4976,3439 4947,3450 4953,3419" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_227"/>
<polygon points="5028,3467 4998,3477 5004,3447" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_228"/>
<circle cx='4901.5' cy='3453.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_229" class="scatter"/>
<polygon points="4949,3497 4937,3484 4946,3468 4964,3471 4966,3490" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_230" class="scatter"/>
<polygon points="5016,3514 4987,3523 4993,3493" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_231"/>
<polygon points="4904,3501 4874,3510 4881,3480" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_232" class="scatter"/>
<circle cx='4940.8' cy='3527.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_233"/>
<polygon points="5004,3560 4974,3569 4981,3539" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_234"/>
<circle cx='4878.5' cy='3541.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_235" class="scatter"/>
<circle cx='4928.1' cy='3571.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_236"/>
<polygon points="4973,3618 4962,3604 4972,3589 4989,3593 4990,3611" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_237"/>
<polygon points="4878,3588 4848,3596 4856,3566" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_238" class="scatter"/>
<polygon points="4927,3620 4897,3628 4906,3598" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_239" class="scatter"/>
<circle cx='4962.9' cy='3648.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_240"/>
<polygon points="4864,3631 4834,3639 4843,3609" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_241"/>
<circle cx='4899.6' cy='3660.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_242"/>
<polygon points="4943,3709 4932,3694 4942,3679 4960,3684 4960,3703" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_243" class="scatter"/>
<circle cx='4836.4' cy='3670.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_244"/>
<polygon points="4897,3708 4866,3715 4876,3685" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_245" class="scatter"/>
<circle cx='4930.8' cy='3738.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_246"/>
<polygon points="4833,3717 4803,3723 4813,3693" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_247" class="scatter"/>
<circle cx='4867.0' cy='3747.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_248"/>
<circle cx='4913.2' cy='3783.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_249"/>
<circle cx='4803.5' cy='3754.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_250"/>
<circle cx='4849.2' cy='3790.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_251" class="scatter"/>
<polygon points="4889,3842 4879,3826 4891,3812 4908,3819 4907,3837" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_252" class="scatter"/>
<circle cx='4785.5' cy='3795.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_253" class="scatter"/>
<circle cx='4830.5' cy='3832.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_254" class="scatter"/>
<polygon points="4869,3885 4859,3869 4871,3856 4888,3863 4887,3881" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_255" class="scatter"/>
<circle cx='4766.6' cy='3837.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_256" class="scatter"/>
<circle cx='4810.7' cy='3875.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_257"/>
<circle cx='4854.3' cy='3913.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_258"/>
<circle cx='4746.8' cy='3877.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_259"/>
<circle cx='4790.0' cy='3916.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_260"/>
<circle cx='4832.7' cy='3956.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_261"/>
<circle cx='4726.1' cy='3917.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_262" class="scatter"/>
<circle cx='4768.3' cy='3957.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_263"/>
<circle cx='4810.1' cy='3998.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_264"/>
<polygon points="4716,3964 4685,3965 4699,3938" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_265"/>
<circle cx='4745.7' cy='3998.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_266"/>
<circle cx='4786.5' cy='4040.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_267"/>
<circle cx='4681.8' cy='3996.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_268" class="scatter"/>
<polygon points="4734,4045 4703,4046 4718,4019" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_269" class="scatter"/>
<circle cx='4762.0' cy='4081.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_270" class="scatter"/>
<polygon points="4651,4049 4643,4032 4657,4020 4672,4029 4669,4047" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_271"/>
<circle cx='4697.7' cy='4078.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_272"/>
<polygon points="4748,4128 4717,4128 4733,4101" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_273" class="scatter"/>
<polygon points="4626,4087 4619,4070 4632,4058 4648,4067 4644,4085" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_274" class="scatter"/>
<polygon points="4664,4130 4657,4114 4671,4102 4687,4111 4682,4129" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_275" class="scatter"/>
<circle cx='4710.1' cy='4161.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_276" class="scatter"/>
<circle cx='4608.6' cy='4110.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_277"/>
<circle cx='4646.0' cy='4155.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_278" class="scatter"/>
<polygon points="4674,4214 4668,4197 4682,4185 4697,4195 4693,4213" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_279"/>
<circle cx='4582.5' cy='4147.7' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_280" class="scatter"/>
<circle cx='4618.9' cy='4193.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_281" class="scatter"/>
<circle cx='4654.6' cy='4239.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_282" class="scatter"/>
<circle cx='4555.6' cy='4184.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_283" class="scatter"/>
<circle cx='4590.8' cy='4230.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_284"/>
<polygon points="4616,4290 4611,4273 4625,4262 4640,4272 4635,4290" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_285" class="scatter"/>
<circle cx='4527.8' cy='4219.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_286" class="scatter"/>
<circle cx='4562.0' cy='4266.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_287"/>
<polygon points="4606,4323 4575,4319 4594,4294" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_288" class="scatter"/>
<circle cx='4499.2' cy='4254.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_289"/>
<circle cx='4532.2' cy='4302.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_290"/>
<circle cx='4564.7' cy='4351.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_291" class="scatter"/>
<polygon points="4480,4297 4450,4293 4469,4268" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_292"/>
<circle cx='4501.7' cy='4337.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_293"/>
<circle cx='4533.0' cy='4386.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_294"/>
<polygon points="4450,4331 4419,4326 4439,4302" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_295" class="scatter"/>
<circle cx='4470.4' cy='4372.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_296"/>
<circle cx='4500.5' cy='4421.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_297"/>
<circle cx='4408.6' cy='4355.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_298"/>
<polygon points="4448,4415 4418,4408 4439,4385" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_299" class="scatter"/>
<circle cx='4467.3' cy='4456.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_300" class="scatter"/>
<circle cx='4376.9' cy='4387.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_301" class="scatter"/>
<polygon points="4395,4450 4391,4432 4407,4423 4421,4436 4413,4452" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_302"/>
<polygon points="4443,4499 4413,4492 4434,4469" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_303"/>
<circle cx='4344.4' cy='4419.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_304"/>
<circle cx='4371.7' cy='4470.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_305" class="scatter"/>
<polygon points="4408,4532 4378,4524 4400,4502" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_306" class="scatter"/>
<circle cx='4311.2' cy='4449.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_307" class="scatter"/>
<polygon points="4326,4513 4324,4495 4340,4487 4353,4500 4344,4516" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_308"/>
<polygon points="4372,4564 4342,4555 4365,4534" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_309" class="scatter"/>
<polygon points="4287,4490 4257,4481 4279,4459" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_310"/>
<circle cx='4302.3' cy='4532.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_311"/>
<polygon points="4336,4595 4306,4586 4329,4565" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_312"/>
<polygon points="4252,4519 4222,4509 4245,4489" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_313" class="scatter"/>
<polygon points="4255,4572 4253,4554 4270,4547 4282,4561 4273,4576" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_314" class="scatter"/>
<polygon points="4278,4626 4276,4608 4293,4601 4305,4614 4296,4630" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_315" class="scatter"/>
<circle cx='4207.5' cy='4537.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_316"/>
<circle cx='4230.0' cy='4591.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_317" class="scatter"/>
<circle cx='4251.7' cy='4645.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_318" class="scatter"/>
<circle cx='4171.7' cy='4564.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_319" class="scatter"/>
<circle cx='4192.9' cy='4619.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_320"/>
<circle cx='4213.4' cy='4673.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_321" class="scatter"/>
<circle cx='4135.2' cy='4591.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_322" class="scatter"/>
<circle cx='4155.1' cy='4646.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_323" class="scatter"/>
<circle cx='4174.3' cy='4701.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_324"/>
<circle cx='4098.1' cy='4617.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_325" class="scatter"/>
<circle cx='4116.8' cy='4672.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_326" class="scatter"/>
<polygon points="4122,4737 4122,4719 4140,4713 4150,4728 4139,4743" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_327"/>
<polygon points="4048,4651 4048,4633 4065,4628 4076,4642 4065,4657" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_328" class="scatter"/>
<polygon points="4085,4709 4057,4696 4083,4678" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_329"/>
<circle cx='4094.4' cy='4753.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_330" class="scatter"/>
<circle cx='4022.1' cy='4666.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_331" class="scatter"/>
<circle cx='4038.2' cy='4722.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_332" class="scatter"/>
<circle cx='4053.6' cy='4778.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_333" class="scatter"/>
<circle cx='3983.3' cy='4689.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_334"/>
<polygon points="4005,4757 3978,4743 4004,4726" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_335"/>
<circle cx='4012.1' cy='4802.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_336"/>
<circle cx='3944.0' cy='4711.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_337" class="scatter"/>
<circle cx='3957.5' cy='4768.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_338"/>
<circle cx='3970.2' cy='4825.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_339"/>
<circle cx='3904.1' cy='4733.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_340"/>
<polygon points="3923,4802 3896,4786 3923,4771" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_341"/>
<circle cx='3927.7' cy='4847.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_342"/>
<circle cx='3863.8' cy='4753.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_343" class="scatter"/>
<circle cx='3874.7' cy='4810.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_344" class="scatter"/>
<polygon points="3891,4880 3865,4864 3892,4849" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_345"/>
<circle cx='3823.0' cy='4773.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_346"/>
<circle cx='3832.6' cy='4830.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_347" class="scatter"/>
<circle cx='3841.3' cy='4888.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_348" class="scatter"/>
<polygon points="3768,4799 3771,4781 3789,4778 3797,4794 3784,4807" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_349"/>
<polygon points="3796,4861 3770,4844 3798,4831" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_350"/>
<circle cx='3797.4' cy='4907.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_351" class="scatter"/>
<circle cx='3740.2' cy='4809.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_352" class="scatter"/>
<polygon points="3753,4879 3727,4861 3756,4849" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_353" class="scatter"/>
<circle cx='3753.1' cy='4925.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_354"/>
<polygon points="3703,4838 3679,4820 3707,4808" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_355" class="scatter"/>
<polygon points="3689,4890 3694,4872 3712,4871 3719,4887 3705,4899" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_356"/>
<polygon points="3714,4954 3689,4936 3718,4924" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_357"/>
<circle cx='3655.7' cy='4841.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_358"/>
<circle cx='3659.9' cy='4899.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_359"/>
<circle cx='3663.3' cy='4957.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_360"/>
<circle cx='3612.9' cy='4856.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_361"/>
<circle cx='3615.8' cy='4914.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_362"/>
<polygon points="3622,4985 3599,4965 3628,4955" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_363" class="scatter"/>
<circle cx='3569.9' cy='4870.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_364"/>
<circle cx='3571.4' cy='4928.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_365" class="scatter"/>
<circle cx='3572.0' cy='4986.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_366"/>
<polygon points="3531,4895 3508,4875 3537,4865" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_367" class="scatter"/>
<polygon points="3531,4954 3508,4933 3537,4923" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_368"/>
<polygon points="3511,5004 3517,4987 3535,4987 3541,5004 3526,5015" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_369"/>
<circle cx='3482.8' cy='4894.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_370" class="scatter"/>
<circle cx='3481.6' cy='4952.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_371"/>
<circle cx='3479.6' cy='5010.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_372" class="scatter"/>
<polygon points="3442,4918 3420,4896 3450,4888" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_373"/>
<polygon points="3440,4976 3418,4954 3448,4946" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_374" class="scatter"/>
<polygon points="3436,5034 3415,5012 3445,5004" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_375"/>
<circle cx='3394.7' cy='4914.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_376"/>
<circle cx='3390.8' cy='4972.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_377"/>
<polygon points="3389,5044 3368,5021 3398,5014" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_378" class="scatter"/>
<circle cx='3350.3' cy='4923.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_379" class="scatter"/>
<circle cx='3345.1' cy='4981.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_380"/>
<polygon points="3324,5042 3331,5026 3349,5028 3353,5046 3337,5055" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_381"/>
<polygon points="3308,4944 3288,4921 3318,4915" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_382" class="scatter"/>
<circle cx='3299.2' cy='4988.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_383" class="scatter"/>
<circle cx='3291.8' cy='5046.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_384"/>
<polygon points="3246,4940 3254,4924 3272,4926 3275,4944 3259,4953" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_385"/>
<circle cx='3253.1' cy='4995.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_386"/>
<circle cx='3244.4' cy='5052.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_387" class="scatter"/>
<circle cx='3216.1' cy='4942.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_388"/>
<circle cx='3206.9' cy='5000.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_389" class="scatter"/>
<polygon points="3181,5060 3190,5044 3208,5047 3211,5065 3194,5073" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_390" class="scatter"/>
<circle cx='3171.1' cy='4947.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_391" class="scatter"/>
<circle cx='3160.6' cy='5004.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_392" class="scatter"/>
<polygon points="3151,5075 3132,5050 3163,5047" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_393" class="scatter"/>
<circle cx='3126.1' cy='4950.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_394"/>
<circle cx='3114.2' cy='5007.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_395" class="scatter"/>
<circle cx='3101.5' cy='5064.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_396" class="scatter"/>
<circle cx='3080.9' cy='4953.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_397"/>
<polygon points="3069,5023 3051,4998 3082,4995" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_398"/>
<circle cx='3053.7' cy='5066.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_399"/>
<polygon points="3020,4956 3030,4940 3048,4945 3049,4963 3032,4970" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_400"/>
<polygon points="3022,5024 3005,4998 3036,4997" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_401"/>
<polygon points="3007,5081 2990,5055 3021,5053" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_402" class="scatter"/>
<circle cx='2990.5' cy='4954.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_403"/>
<circle cx='2974.7' cy='5010.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_404" class="scatter"/>
<circle cx='2958.1' cy='5066.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_405"/>
<polygon points="2946,4968 2930,4941 2961,4940" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_406"/>
<circle cx='2928.3' cy='5009.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_407"/>
<circle cx='2910.3' cy='5065.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_408"/>
<circle cx='2900.1' cy='4952.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_409"/>
<circle cx='2881.8' cy='5007.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_410" class="scatter"/>
<circle cx='2862.6' cy='5062.7' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_411"/>
<circle cx='2855.0' cy='4949.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_412" class="scatter"/>
<circle cx='2835.4' cy='5004.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_413"/>
<circle cx='2814.9' cy='5058.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_414"/>
<circle cx='2810.0' cy='4945.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_415" class="scatter"/>
<polygon points="2788,5013 2774,4986 2805,4988" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_416"/>
<polygon points="2766,5068 2753,5040 2784,5042" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_417" class="scatter"/>
<circle cx='2765.0' cy='4940.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_418"/>
<polygon points="2742,5008 2729,4980 2759,4982" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_419" class="scatter"/>
<circle cx='2719.9' cy='5048.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_420"/>
<circle cx='2720.2' cy='4934.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_421"/>
<circle cx='2696.9' cy='4988.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_422"/>
<circle cx='2672.6' cy='5041.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_423" class="scatter"/>
<circle cx='2675.6' cy='4927.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_424"/>
<circle cx='2651.0' cy='4980.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_425"/>
<circle cx='2625.5' cy='5033.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_426" class="scatter"/>
<polygon points="2629,4933 2618,4904 2648,4909" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_427" class="scatter"/>
<polygon points="2590,4970 2603,4957 2619,4965 2616,4983 2598,4986" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_428"/>
<circle cx='2578.6' cy='5023.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_429"/>
<polygon points="2585,4924 2574,4895 2604,4900" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_430" class="scatter"/>
<polygon points="2557,4976 2547,4946 2577,4952" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_431"/>
<circle cx='2531.9' cy='5013.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_432"/>
<polygon points="2540,4914 2530,4885 2560,4890" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_433" class="scatter"/>
<circle cx='2514.5' cy='4951.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_434" class="scatter"/>
<polygon points="2483,5015 2473,4986 2503,4992" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_435" class="scatter"/>
<circle cx='2498.9' cy='4889.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_436" class="scatter"/>
<circle cx='2469.5' cy='4939.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_437" class="scatter"/>
<polygon points="2424,4986 2438,4974 2454,4984 2449,5001 2431,5003" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_438"/>
<circle cx='2455.3' cy='4877.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_439"/>
<circle cx='2424.8' cy='4927.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_440"/>
<polygon points="2390,4989 2382,4959 2412,4967" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_441"/>
<circle cx='2412.0' cy='4864.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_442" class="scatter"/>
<circle cx='2380.4' cy='4913.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_443" class="scatter"/>
<circle cx='2347.9' cy='4961.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_444"/>
<circle cx='2369.1' cy='4850.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_445" class="scatter"/>
<circle cx='2336.3' cy='4898.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_446" class="scatter"/>
<circle cx='2302.7' cy='4946.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_447" class="scatter"/>
<circle cx='2326.5' cy='4835.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_448" class="scatter"/>
<circle cx='2292.6' cy='4882.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_449" class="scatter"/>
<circle cx='2257.9' cy='4929.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_450"/>
<circle cx='2284.2' cy='4819.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_451" class="scatter"/>
<polygon points="2235,4861 2250,4850 2264,4861 2258,4878 2240,4878" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_452"/>
<circle cx='2213.5' cy='4911.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_453"/>
<polygon points="2228,4797 2243,4787 2257,4798 2251,4815 2233,4814" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_454"/>
<circle cx='2206.3' cy='4847.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_455" class="scatter"/>
<circle cx='2169.5' cy='4893.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_456"/>
<polygon points="2196,4797 2191,4766 2220,4777" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_457"/>
<polygon points="2159,4841 2154,4811 2183,4822" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_458" class="scatter"/>
<polygon points="2112,4867 2127,4858 2141,4870 2134,4887 2116,4885" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_459"/>
<polygon points="2155,4777 2151,4747 2179,4759" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_460" class="scatter"/>
<polygon points="2107,4803 2123,4794 2137,4806 2130,4822 2111,4821" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_461"/>
<circle cx='2082.9' cy='4852.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_462" class="scatter"/>
<circle cx='2119.2' cy='4745.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_463"/>
<polygon points="2066,4782 2082,4773 2095,4785 2088,4802 2070,4800" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_464" class="scatter"/>
<polygon points="2035,4843 2032,4812 2060,4825" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_465" class="scatter"/>
<circle cx='2079.1' cy='4724.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_466" class="scatter"/>
<polygon points="2033,4779 2031,4748 2059,4761" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_467" class="scatter"/>
<circle cx='1998.2' cy='4808.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_468"/>
<circle cx='2039.5' cy='4702.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_469" class="scatter"/>
<polygon points="1992,4756 1991,4725 2018,4739" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_470"/>
<polygon points="1950,4796 1949,4766 1977,4780" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_471" class="scatter"/>
<circle cx='2000.4' cy='4680.0' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_472" class="scatter"/>
<polygon points="1945,4713 1961,4705 1974,4718 1965,4734 1947,4731" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_473"/>
<circle cx='1915.6' cy='4760.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_474" class="scatter"/>
<polygon points="1955,4668 1955,4637 1982,4652" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_475" class="scatter"/>
<polygon points="1912,4707 1912,4676 1939,4692" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_476"/>
<polygon points="1862,4727 1879,4719 1891,4733 1881,4749 1864,4745" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_477" class="scatter"/>
<polygon points="1910,4624 1927,4617 1939,4631 1930,4646 1912,4642" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_478"/>
<polygon points="1873,4682 1874,4651 1900,4667" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_479"/>
<circle cx='1835.4' cy='4708.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_480"/>
<polygon points="1879,4618 1880,4587 1907,4604" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_481" class="scatter"/>
<polygon points="1834,4655 1836,4624 1862,4641" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_482"/>
<polygon points="1789,4692 1791,4661 1817,4678" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_483" class="scatter"/>
<circle cx='1849.4' cy='4580.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_484" class="scatter"/>
<circle cx='1803.9' cy='4616.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_485" class="scatter"/>
<circle cx='1757.7' cy='4652.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_486"/>
<circle cx='1813.2' cy='4553.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_487"/>
<circle cx='1766.8' cy='4588.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_488" class="scatter"/>
<polygon points="1712,4634 1715,4603 1740,4621" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_489" class="scatter"/>
<circle cx='1777.6' cy='4525.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_490" class="scatter"/>
<circle cx='1730.4' cy='4559.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_491"/>
<circle cx='1682.6' cy='4593.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_492"/>
<polygon points="1734,4508 1739,4477 1763,4496" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_493" class="scatter"/>
<polygon points="1686,4540 1691,4510 1715,4529" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_494"/>
<polygon points="1638,4573 1642,4542 1667,4561" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_495" class="scatter"/>
<circle cx='1708.4' cy='4467.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_496" class="scatter"/>
<polygon points="1648,4489 1665,4485 1675,4500 1664,4514 1647,4508" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_497" class="scatter"/>
<circle cx='1610.4' cy='4530.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_498"/>
<polygon points="1666,4447 1672,4417 1695,4437" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_499" class="scatter"/>
<circle cx='1625.4' cy='4467.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_500" class="scatter"/>
<circle cx='1575.4' cy='4498.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_501" class="scatter"/>
<circle cx='1641.9' cy='4406.1' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_502"/>
<circle cx='1591.8' cy='4435.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_503"/>
<polygon points="1530,4454 1548,4451 1557,4466 1544,4480 1528,4472" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_504"/>
<polygon points="1601,4384 1608,4354 1630,4375" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_505" class="scatter"/>
<circle cx='1559.0' cy='4402.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_506"/>
<circle cx='1507.6' cy='4430.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_507"/>
<circle cx='1578.3' cy='4341.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_508" class="scatter"/>
<polygon points="1517,4379 1525,4349 1547,4370" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_509"/>
<polygon points="1464,4385 1482,4382 1490,4398 1477,4411 1461,4403" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_510"/>
<circle cx='1547.7' cy='4308.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_511"/>
<polygon points="1485,4324 1503,4321 1511,4337 1498,4350 1482,4341" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_512" class="scatter"/>
<circle cx='1443.1' cy='4360.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_513" class="scatter"/>
<polygon points="1508,4284 1517,4254 1538,4277" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_514" class="scatter"/>
<polygon points="1455,4288 1473,4286 1480,4303 1467,4315 1451,4306" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_515" class="scatter"/>
<polygon points="1402,4312 1420,4310 1427,4327 1414,4339 1398,4330" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_516"/>
<circle cx='1488.7' cy='4240.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_517"/>
<polygon points="1425,4273 1435,4243 1456,4266" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_518"/>
<circle cx='1381.9' cy='4286.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_519"/>
<circle cx='1460.5' cy='4204.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_520"/>
<polygon points="1397,4215 1415,4214 1422,4231 1408,4243 1392,4233" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_521"/>
<circle cx='1352.5' cy='4248.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_522" class="scatter"/>
<polygon points="1423,4157 1441,4156 1448,4173 1434,4184 1419,4174" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_523"/>
<circle cx='1378.8' cy='4190.0' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_524" class="scatter"/>
<polygon points="1314,4198 1333,4197 1339,4215 1325,4226 1310,4216" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_525" class="scatter"/>
<circle cx='1406.4' cy='4132.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_526" class="scatter"/>
<polygon points="1341,4160 1353,4132 1372,4156" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_527"/>
<circle cx='1296.6' cy='4171.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_528" class="scatter"/>
<circle cx='1380.7' cy='4095.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_529"/>
<circle cx='1325.5' cy='4113.7' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_530"/>
<circle cx='1269.9' cy='4131.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_531" class="scatter"/>
<circle cx='1355.8' cy='4057.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_532" class="scatter"/>
<circle cx='1300.2' cy='4074.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_533" class="scatter"/>
<polygon points="1233,4099 1247,4071 1264,4096" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_534"/>
<polygon points="1321,4027 1334,3999 1352,4024" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_535"/>
<polygon points="1265,4043 1278,4015 1296,4041" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_536" class="scatter"/>
<circle cx='1219.5' cy='4050.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_537"/>
<circle cx='1308.6' cy='3980.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_538"/>
<circle cx='1252.3' cy='3995.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_539" class="scatter"/>
<polygon points="1184,4016 1199,3989 1215,4015" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_540" class="scatter"/>
<polygon points="1275,3948 1290,3921 1306,3947" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_541" class="scatter"/>
<circle cx='1229.8' cy='3954.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_542"/>
<polygon points="1161,3974 1177,3947 1192,3973" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_543" class="scatter"/>
<circle cx='1265.1' cy='3901.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_544"/>
<circle cx='1208.2' cy='3913.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_545" class="scatter"/>
<circle cx='1150.9' cy='3924.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_546" class="scatter"/>
<circle cx='1244.8' cy='3860.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_547"/>
<circle cx='1187.5' cy='3871.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_548"/>
<polygon points="1118,3888 1135,3861 1149,3889" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_549"/>
<circle cx='1225.3' cy='3819.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_550"/>
<circle cx='1167.9' cy='3829.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_551"/>
<circle cx='1110.2' cy='3837.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_552"/>
<polygon points="1195,3784 1212,3759 1226,3787" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_553" class="scatter"/>
<circle cx='1149.2' cy='3786.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_554" class="scatter"/>
<polygon points="1085,3780 1103,3783 1105,3801 1088,3809 1076,3796" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_555"/>
<circle cx='1189.3' cy='3736.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_556"/>
<circle cx='1131.5' cy='3743.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_557"/>
<circle cx='1073.5' cy='3749.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_558" class="scatter"/>
<polygon points="1160,3700 1179,3675 1191,3704" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_559"/>
<circle cx='1114.8' cy='3700.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_560"/>
<circle cx='1056.6' cy='3704.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_561" class="scatter"/>
<polygon points="1145,3657 1164,3633 1175,3662" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_562"/>
<circle cx='1099.1' cy='3656.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_563"/>
<polygon points="1028,3665 1048,3640 1059,3669" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_564"/>
<circle cx='1142.6' cy='3609.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_565" class="scatter"/>
<polygon points="1079,3598 1097,3603 1097,3621 1080,3627 1069,3613" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_566" class="scatter"/>
<circle cx='1026.1' cy='3614.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_567" class="scatter"/>
<circle cx='1129.0' cy='3566.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_568" class="scatter"/>
<circle cx='1070.8' cy='3567.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_569"/>
<circle cx='1012.5' cy='3568.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_570"/>
<polygon points="1104,3527 1124,3504 1134,3534" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_571"/>
<circle cx='1058.2' cy='3523.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_572" class="scatter"/>
<circle cx='999.8' cy='3522.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_573"/>
<circle cx='1104.8' cy='3479.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_574" class="scatter"/>
<circle cx='1046.6' cy='3478.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_575" class="scatter"/>
<circle cx='988.3' cy='3476.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_576" class="scatter"/>
<polygon points="1081,3439 1103,3417 1111,3447" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_577" class="scatter"/>
<circle cx='1036.1' cy='3432.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_578"/>
<circle cx='977.8' cy='3429.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_579"/>
<circle cx='1084.7' cy='3391.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_580" class="scatter"/>
<circle cx='1026.6' cy='3387.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_581"/>
<polygon points="955,3385 978,3364 985,3394" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_582" class="scatter"/>
<circle cx='1076.1' cy='3346.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_583"/>
<circle cx='1018.1' cy='3341.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_584" class="scatter"/>
<circle cx='960.1' cy='3335.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_585" class="scatter"/>
<circle cx='1068.6' cy='3302.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_586" class="scatter"/>
<polygon points="1008,3280 1024,3288 1022,3306 1004,3310 995,3294" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_587"/>
<polygon points="950,3273 967,3281 964,3299 946,3302 938,3286" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_588"/>
<polygon points="1049,3260 1073,3240 1078,3270" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_589" class="scatter"/>
<circle cx='1004.5' cy='3249.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_590"/>
<circle cx='946.8' cy='3240.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_591" class="scatter"/>
<polygon points="1054,3197 1071,3206 1068,3224 1050,3226 1041,3210" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_592"/>
<circle cx='999.2' cy='3203.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_593"/>
<polygon points="940,3178 956,3186 953,3204 934,3207 927,3190" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_594"/>
<circle cx='1052.3' cy='3167.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_595" class="scatter"/>
<polygon points="982,3159 1007,3140 1010,3171" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_596"/>
<polygon points="925,3147 949,3129 953,3159" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_597"/>
<circle cx='1049.0' cy='3122.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_598" class="scatter"/>
<circle cx='992.0' cy='3110.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_599"/>
<polygon points="922,3099 947,3081 950,3112" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_600" class="scatter"/>
<circle cx='1046.6' cy='3077.4' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_601"/>
<circle cx='990.0' cy='3064.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_602" class="scatter"/>
<polygon points="932,3035 948,3044 943,3062 925,3063 918,3046" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_603"/>
<circle cx='1045.4' cy='3032.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_604" class="scatter"/>
<circle cx='989.0' cy='3017.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_605" class="scatter"/>
<polygon points="932,2987 947,2997 942,3014 924,3015 918,2998" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_606"/>
<circle cx='1045.2' cy='2987.0' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_607" class="scatter"/>
<circle cx='989.1' cy='2971.1' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_608" class="scatter"/>
<polygon points="920,2955 946,2939 947,2970" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_609" class="scatter"/>
<polygon points="1046,2926 1061,2937 1055,2954 1037,2954 1031,2937" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_610" class="scatter"/>
<circle cx='990.3' cy='2924.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_611"/>
<circle cx='934.9' cy='2906.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_612" class="scatter"/>
<polygon points="1048,2881 1063,2892 1057,2909 1039,2909 1033,2892" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_613" class="scatter"/>
<circle cx='992.6' cy='2878.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_614"/>
<polygon points="924,2859 951,2844 951,2875" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_615"/>
<circle cx='1050.8' cy='2851.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_616"/>
<circle cx='996.0' cy='2831.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_617" class="scatter"/>
<circle cx='941.4' cy='2811.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_618"/>
<polygon points="1041,2806 1069,2792 1067,2823" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_619"/>
<circle cx='1000.4' cy='2785.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_620" class="scatter"/>
<polygon points="933,2763 961,2749 959,2780" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_621" class="scatter"/>
<circle cx='1059.7' cy='2761.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_622" class="scatter"/>
<circle cx='1005.9' cy='2739.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_623" class="scatter"/>
<circle cx='952.3' cy='2716.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_624"/>
<polygon points="1052,2715 1081,2703 1078,2734" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_625"/>
<circle cx='1012.5' cy='2693.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_626"/>
<circle cx='959.4' cy='2669.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_627" class="scatter"/>
<circle cx='1072.8' cy='2672.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_628" class="scatter"/>
<circle cx='1020.1' cy='2647.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_629" class="scatter"/>
<polygon points="954,2620 983,2608 979,2639" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_630"/>
<polygon points="1068,2626 1096,2614 1092,2645" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_631"/>
<circle cx='1028.8' cy='2601.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_632" class="scatter"/>
<polygon points="979,2560 992,2573 984,2589 966,2586 963,2568" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_633"/>
<polygon points="1077,2581 1106,2570 1101,2601" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_634"/>
<polygon points="1041,2541 1054,2554 1045,2570 1027,2567 1025,2549" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_635" class="scatter"/>
<circle cx='987.3' cy='2528.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_636"/>
<polygon points="1087,2537 1116,2527 1110,2557" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_637" class="scatter"/>
<circle cx='1049.3' cy='2511.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_638"/>
<polygon points="986,2479 1015,2470 1009,2500" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_639" class="scatter"/>
<circle cx='1111.3' cy='2495.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_640" class="scatter"/>
<polygon points="1065,2451 1077,2465 1067,2480 1049,2476 1048,2458" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_641"/>
<circle cx='1011.3' cy='2435.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_642" class="scatter"/>
<polygon points="1127,2437 1139,2451 1129,2466 1112,2462 1110,2444" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_643"/>
<polygon points="1061,2418 1091,2410 1083,2440" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_644" class="scatter"/>
<circle cx='1024.8' cy='2389.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_645"/>
<circle cx='1136.7' cy='2408.7' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_646"/>
<circle cx='1087.9' cy='2376.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_647"/>
<circle cx='1039.5' cy='2344.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_648" class="scatter"/>
<polygon points="1155,2351 1166,2365 1156,2380 1139,2375 1138,2357" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_649"/>
<circle cx='1102.8' cy='2332.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_650"/>
<circle cx='1055.2' cy='2299.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_651"/>
<polygon points="1153,2319 1184,2312 1174,2342" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_652"/>
<circle cx='1118.7' cy='2289.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_653" class="scatter"/>
<polygon points="1077,2240 1087,2255 1077,2269 1059,2263 1059,2245" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_654" class="scatter"/>
<polygon points="1187,2266 1198,2281 1187,2296 1169,2290 1170,2272" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_655"/>
<circle cx='1135.7' cy='2245.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_656"/>
<polygon points="1077,2205 1108,2200 1097,2229" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_657"/>
<circle cx='1199.3' cy='2239.1' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_658"/>
<polygon points="1141,2198 1172,2193 1161,2222" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_659"/>
<circle cx='1108.4' cy='2166.1' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_660"/>
<circle cx='1217.4' cy='2197.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_661"/>
<circle cx='1172.5' cy='2160.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_662" class="scatter"/>
<circle cx='1128.2' cy='2122.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_663"/>
<circle cx='1236.4' cy='2156.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_664" class="scatter"/>
<polygon points="1199,2104 1208,2120 1196,2134 1179,2126 1181,2108" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_665" class="scatter"/>
<circle cx='1149.0' cy='2079.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_666"/>
<polygon points="1244,2111 1275,2108 1262,2136" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_667"/>
<polygon points="1201,2071 1232,2068 1219,2097" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_668" class="scatter"/>
<polygon points="1159,2031 1190,2029 1176,2057" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_669" class="scatter"/>
<circle cx='1277.3' cy='2076.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_670" class="scatter"/>
<polygon points="1223,2030 1254,2028 1240,2056" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_671" class="scatter"/>
<circle cx='1193.5' cy='1994.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_672" class="scatter"/>
<circle cx='1299.1' cy='2036.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_673"/>
<circle cx='1257.9' cy='1995.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_674" class="scatter"/>
<circle cx='1217.3' cy='1953.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_675"/>
<polygon points="1310,1991 1341,1990 1326,2017" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_676"/>
<circle cx='1281.6' cy='1955.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_677" class="scatter"/>
<polygon points="1230,1906 1261,1906 1246,1933" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_678"/>
<circle cx='1345.5' cy='1958.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_679" class="scatter"/>
<circle cx='1306.2' cy='1915.8' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_680"/>
<polygon points="1275,1859 1283,1875 1269,1888 1253,1878 1257,1860" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_681"/>
<circle cx='1370.0' cy='1920.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_682" class="scatter"/>
<polygon points="1340,1864 1347,1881 1333,1892 1317,1883 1322,1865" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_683"/>
<polygon points="1302,1819 1309,1836 1295,1848 1280,1838 1284,1820" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_684" class="scatter"/>
<circle cx='1395.4' cy='1883.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_685"/>
<circle cx='1358.2' cy='1838.6' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_686" class="scatter"/>
<circle cx='1321.6' cy='1793.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_687"/>
<circle cx='1421.6' cy='1846.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_688" class="scatter"/>
<polygon points="1374,1793 1405,1796 1388,1821" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_689"/>
<circle cx='1349.9' cy='1754.7' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_690"/>
<circle cx='1448.7' cy='1810.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_691"/>
<circle cx='1413.6' cy='1764.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_692"/>
<polygon points="1368,1709 1399,1712 1381,1737" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_693" class="scatter"/>
<circle cx='1476.6' cy='1774.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_694"/>
<circle cx='1442.6' cy='1727.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_695" class="scatter"/>
<circle cx='1409.3' cy='1679.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_696" class="scatter"/>
<polygon points="1495,1732 1525,1736 1507,1760" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_697" class="scatter"/>
<circle cx='1472.5' cy='1691.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_698"/>
<polygon points="1430,1635 1460,1640 1441,1664" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_699" class="scatter"/>
<circle cx='1534.9' cy='1705.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_700"/>
<polygon points="1493,1648 1523,1653 1504,1677" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_701" class="scatter"/>
<polygon points="1462,1599 1492,1604 1472,1628" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_702" class="scatter"/>
<circle cx='1565.2' cy='1672.2' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_703" class="scatter"/>
<circle cx='1534.6' cy='1622.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_704"/>
<polygon points="1495,1564 1525,1570 1505,1593" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_705" class="scatter"/>
<circle cx='1596.3' cy='1639.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_706"/>
<circle cx='1566.8' cy='1589.2' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_707" class="scatter"/>
<polygon points="1528,1529 1558,1536 1537,1559" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_708"/>
<circle cx='1628.2' cy='1607.3' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_709" class="scatter"/>
<polygon points="1590,1547 1620,1554 1599,1577" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_710"/>
<circle cx='1572.2' cy='1505.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_711"/>
<circle cx='1660.7' cy='1575.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_712"/>
<polygon points="1624,1515 1654,1523 1632,1545" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_713"/>
<circle cx='1607.2' cy='1472.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_714"/>
<polygon points="1705,1534 1708,1553 1691,1561 1679,1548 1687,1531" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_715" class="scatter"/>
<polygon points="1659,1484 1689,1492 1666,1514" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_716" class="scatter"/>
<circle cx='1642.9' cy='1440.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_717" class="scatter"/>
<circle cx='1728.0' cy='1515.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_718" class="scatter"/>
<polygon points="1694,1453 1724,1462 1701,1483" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_719" class="scatter"/>
<circle cx='1679.3' cy='1409.7' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_720" class="scatter"/>
<circle cx='1762.7' cy='1486.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_721"/>
<circle cx='1739.2' cy='1433.3' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_722"/>
<polygon points="1708,1369 1737,1380 1713,1400" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_723" class="scatter"/>
<polygon points="1810,1448 1811,1466 1794,1473 1783,1460 1792,1444" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_724" class="scatter"/>
<circle cx='1775.7' cy='1404.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_725"/>
<circle cx='1754.2' cy='1350.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_726" class="scatter"/>
<circle cx='1834.0' cy='1430.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_727"/>
<circle cx='1813.0' cy='1376.6' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_728"/>
<circle cx='1792.7' cy='1321.9' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_729"/>
<circle cx='1870.6' cy='1404.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_730" class="scatter"/>
<circle cx='1850.8' cy='1349.6' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_731"/>
<circle cx='1831.8' cy='1294.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_732" class="scatter"/>
<circle cx='1907.8' cy='1378.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_733" class="scatter"/>
<circle cx='1889.3' cy='1323.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_734" class="scatter"/>
<circle cx='1871.6' cy='1267.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_735" class="scatter"/>
<circle cx='1945.6' cy='1353.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_736"/>
<circle cx='1928.4' cy='1298.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_737"/>
<circle cx='1911.9' cy='1242.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_738" class="scatter"/>
<circle cx='1983.9' cy='1329.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_739" class="scatter"/>
<circle cx='1968.0' cy='1273.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_740" class="scatter"/>
<circle cx='1952.9' cy='1217.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_741" class="scatter"/>
<polygon points="2036,1299 2035,1317 2017,1321 2007,1306 2019,1292" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_742"/>
<circle cx='2008.2' cy='1250.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_743" class="scatter"/>
<circle cx='1994.4' cy='1193.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_744"/>
<circle cx='2062.2' cy='1284.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_745"/>
<polygon points="2062,1220 2061,1238 2043,1242 2033,1227 2045,1213" style="fill:rgb(65,171,93);" class="scatter" id="scat_Aromatic_Residue_746"/>
<circle cx='2036.4' cy='1171.1' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_747" class="scatter"/>
<circle cx='2102.1' cy='1263.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_748"/>
<circle cx='2090.1' cy='1206.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_749" class="scatter"/>
<circle cx='2079.0' cy='1149.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_750" class="scatter"/>
<circle cx='2142.5' cy='1243.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_751"/>
<circle cx='2131.9' cy='1186.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_752" class="scatter"/>
<circle cx='2122.0' cy='1128.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_753" class="scatter"/>
<circle cx='2183.4' cy='1223.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_754"/>
<circle cx='2174.0' cy='1166.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_755"/>
<circle cx='2165.5' cy='1108.7' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_756"/>
<circle cx='2224.7' cy='1205.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_757"/>
<circle cx='2216.7' cy='1147.8' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_758" class="scatter"/>
<circle cx='2209.5' cy='1089.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_759" class="scatter"/>
<circle cx='2266.4' cy='1188.0' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_760"/>
<circle cx='2259.7' cy='1130.2' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_761"/>
<polygon points="2268,1066 2264,1084 2246,1085 2239,1069 2252,1057" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_762" class="scatter"/>
<circle cx='2308.5' cy='1171.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_763"/>
<circle cx='2303.1' cy='1113.5' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_764"/>
<circle cx='2298.6' cy='1055.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_765"/>
<polygon points="2346,1144 2370,1163 2342,1174" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_766" class="scatter"/>
<polygon points="2342,1085 2366,1105 2337,1116" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_767"/>
<polygon points="2339,1027 2363,1047 2334,1058" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_768" class="scatter"/>
<polygon points="2389,1129 2413,1149 2384,1159" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_769"/>
<polygon points="2386,1071 2410,1091 2381,1101" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_770"/>
<polygon points="2385,1012 2408,1032 2379,1043" style="fill:rgb(239,59,44);" class="scatter" id="scat_Positive_Residue_771"/>
<circle cx='2436.9' cy='1128.0' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_772"/>
<polygon points="2431,1057 2455,1077 2425,1087" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_773" class="scatter"/>
<circle cx='2435.1' cy='1011.4' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_774" class="scatter"/>
<polygon points="2476,1103 2499,1123 2470,1133" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_775" class="scatter"/>
<circle cx='2480.4' cy='1057.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_776"/>
<circle cx='2481.3' cy='998.9' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_777" class="scatter"/>
<polygon points="2520,1091 2543,1112 2513,1121" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_778" class="scatter"/>
<circle cx='2525.4' cy='1045.7' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_779"/>
<circle cx='2527.7' cy='987.4' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_780"/>
<polygon points="2583,1089 2577,1106 2558,1106 2554,1088 2569,1078" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_781" class="scatter"/>
<circle cx='2570.8' cy='1035.3' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_782" class="scatter"/>
<circle cx='2574.4' cy='977.1' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_783"/>
<circle cx='2612.2' cy='1084.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_784" class="scatter"/>
<polygon points="2613,1013 2635,1035 2604,1043" style="fill:rgb(66,146,198);" class="scatter" id="scat_Negative_Residue_785"/>
<circle cx='2621.2' cy='967.8' r='15.5' style="fill:rgb(115,115,115);" class="scatter" id="scat_Nonpolar_Residue_786"/>
<circle cx='2656.7' cy='1075.5' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_787"/>
<polygon points="2659,1004 2680,1027 2650,1034" style="fill:rgb(239,59,44);" id="scat_Positive_Residue_788" class="scatter"/>
<circle cx='2668.3' cy='959.5' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_789" class="scatter"/>
<polygon points="2699,1055 2719,1078 2689,1084" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_790" class="scatter"/>
<circle cx='2708.0' cy='1010.2' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_791"/>
<circle cx='2715.6' cy='952.4' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_792" class="scatter"/>
<circle cx='2746.0' cy='1061.7' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_793" class="scatter"/>
<circle cx='2754.1' cy='1004.0' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_794" class="scatter"/>
<polygon points="2778,944 2770,960 2752,957 2749,939 2765,931" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_795" class="scatter"/>
<circle cx='2790.9' cy='1056.3' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_796"/>
<circle cx='2800.3' cy='998.9' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_797" class="scatter"/>
<circle cx='2810.6' cy='941.5' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_798" class="scatter"/>
<polygon points="2834,1039 2853,1063 2822,1067" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_799" class="scatter"/>
<polygon points="2845,981 2864,1006 2833,1010" style="fill:rgb(66,146,198);" id="scat_Negative_Residue_800" class="scatter"/>
<circle cx='2858.2' cy='937.6' r='15.5' style="fill:rgb(115,115,115);" id="scat_Nonpolar_Residue_801" class="scatter"/>
<circle cx='2881.0' cy='1048.7' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_802" class="scatter"/>
<circle cx='2893.0' cy='991.8' r='15.5' style="fill:rgb(255,0,255);" id="scat_Polar_Residue_803" class="scatter"/>
<circle cx='2906.0' cy='934.9' r='15.5' style="fill:rgb(255,0,255);" class="scatter" id="scat_Polar_Residue_804"/>
<polygon points="2942,1045 2932,1061 2914,1057 2913,1038 2930,1031" style="fill:rgb(65,171,93);" id="scat_Aromatic_Residue_805" class="scatter"/>
</g>
<g id="plot3">
<g id="plot3-axis">
</g>
<line x1='1765.1' y1='5312.4' x2='1763.7' y2='5315.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1763.7' y1='5315.1' x2='1749.5' y2='5341.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1749.5' y1='5341.5' x2='1748.1' y2='5344.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1762.7" y="5353.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-61.9,1762.7,5353.0)" id="G466W_rsID_rs774978137_1_194" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.997">p.G466W</text>
<line x1='1962.6' y1='5223.4' x2='1961.4' y2='5226.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1961.4' y1='5226.1' x2='1948.7' y2='5253.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1948.7' y1='5253.3' x2='1947.4' y2='5256.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1962.4" y="5264.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-65.0,1962.4,5264.1)" sift="0" id="W459C_rsID_rs11798104_1_80" polyphen2="0.999" class="mut" dbsource="dbSNP" ipvMAF="NA">p.W459C</text>
<line x1='2167.2' y1='512.2' x2='2166.3' y2='509.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2166.3' y1='509.3' x2='2156.7' y2='480.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2156.7' y1='480.9' x2='2155.8' y2='478.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2139.4" y="482.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(71.5,2139.4,482.5)" id="R768W_rsID_rs140016715_1_92" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.995">p.R768W</text>
<line x1='1146.0' y1='1146.6' x2='1143.9' y2='1144.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1143.9' y1='1144.5' x2='1122.7' y2='1123.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1122.7' y1='1123.3' x2='1120.6' y2='1121.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1107.9" y="1132.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(45.0,1107.9,1132.5)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.997" id="R708W_rsID_rs776995986_1_211" sift="0.01">p.R708W</text>
<line x1='5361.7' y1='2335.0' x2='5364.5' y2='2334.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5364.5' y1='2334.2' x2='5393.4' y2='2326.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5393.4' y1='2326.1' x2='5396.3' y2='2325.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5401.8" y="2341.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(344.3,5401.8,2341.3)" id="W163R_rsID_rs777568369_1_212" sift="0.04" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.821">p.W163R</text>
<line x1='5457.9' y1='4282.7' x2='5460.6' y2='4284.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5460.6' y1='4284.1' x2='5487.2' y2='4298.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5487.2' y1='4298.0' x2='5489.8' y2='4299.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5482.8" y="4314.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(27.6,5482.8,4314.9)" polyphen2="0.879" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0.18" id="C261W_rsID_rs1049125260_1_270">p.C261W</text>
<line x1='5226.7' y1='1326.5' x2='5229.1' y2='1324.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5229.1' y1='1324.7' x2='5253.1' y2='1306.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5253.1' y1='1306.6' x2='5255.5' y2='1304.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5266.5" y="1317.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(323.1,5266.5,1317.9)" sift="0" id="R115W_rsID_rs1292756480_1_338" polyphen2="0.848" dbsource="dbSNP" ipvMAF="NA" class="mut">p.R115W</text>
<line x1='1780.0' y1='5513.0' x2='1778.7' y2='5515.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1778.7' y1='5515.7' x2='1765.6' y2='5542.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1765.6' y1='5542.7' x2='1764.3' y2='5545.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1779.2" y="5553.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-64.1,1779.2,5553.7)" sift="0" id="W461R_rsID_rs1476137643_1_436" polyphen2="1" class="mut" ipvMAF="NA" dbsource="dbSNP">p.W461R</text>
<line x1='607.0' y1='2458.6' x2='604.1' y2='2457.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='604.1' y1='2457.9' x2='574.8' y2='2451.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='574.8' y1='2451.3' x2='571.9' y2='2450.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="567.2" y="2467.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(12.7,567.2,2467.0)" id="W635R_rsID_rs1569236210_1_443" sift="0.01" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.999">p.W635R</text>
<line x1='1451.1' y1='4902.8' x2='1449.2' y2='4905.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1449.2' y1='4905.1' x2='1430.3' y2='4928.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1430.3' y1='4928.4' x2='1428.4' y2='4930.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1441.0" y="4942.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-50.9,1441.0,4942.2)" polyphen2="0.591" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0.02" id="V491M_rsID_rs750415079_1_60">p.V491M</text>
<line x1='3495.3' y1='5403.0' x2='3496.0' y2='5405.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3496.0' y1='5405.9' x2='3488.1' y2='5438.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3488.1' y1='5438.1' x2='3488.7' y2='5441.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3472.2" y="5445.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(78.7,3472.2,5445.3)" id="M376T_rsID_rs754076967_1_76" sift="0" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.988">p.M376T</text>
<line x1='3678.9' y1='5357.7' x2='3679.8' y2='5360.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3679.8' y1='5360.6' x2='3688.1' y2='5389.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3688.1' y1='5389.4' x2='3688.9' y2='5392.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3672.8" y="5397.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(73.9,3672.8,5397.9)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.995" id="M366T_rsID_rs758568640_1_117" sift="0.01">p.M366T</text>
<line x1='2154.3' y1='5480.3' x2='2153.3' y2='5483.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2153.3' y1='5483.1' x2='2143.6' y2='5511.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2143.6' y1='5511.5' x2='2142.7' y2='5514.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2158.0" y="5520.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-71.2,2158.0,5520.6)" sift="0.02" id="T445M_rsID_rs764772589_1_148" polyphen2="0.949" class="mut" ipvMAF="NA" dbsource="dbSNP">p.T445M</text>
<line x1='5372.5' y1='4455.8' x2='5375.0' y2='4457.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5375.0' y1='4457.3' x2='5400.6' y2='4473.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5400.6' y1='4473.0' x2='5403.1' y2='4474.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5395.1" y="4489.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(31.5,5395.1,4489.6)" polyphen2="0.759" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="M270V_rsID_rs766319182_1_156">p.M270V</text>
<line x1='5020.4' y1='4914.6' x2='5022.6' y2='4916.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5022.6' y1='4916.7' x2='5044.4' y2='4937.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5044.4' y1='4937.3' x2='5046.6' y2='4939.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5035.6" y="4952.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(43.5,5035.6,4952.4)" sift="0.06" id="M297V_rsID_rs772143709_2_183" polyphen2="0.089" class="mut" ipvMAF="NA" dbsource="dbSNP">p.M297V</text>
<line x1='5448.1' y1='2837.4' x2='5451.1' y2='2837.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5451.1' y1='2837.2' x2='5481.0' y2='2835.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5481.0' y1='2835.2' x2='5484.0' y2='2835.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5486.1" y="2851.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(356.2,5486.1,2851.9)" sift="0.03" id="M190T_rsID_rs976723413_1_256" polyphen2="0.882" class="mut" ipvMAF="NA" dbsource="dbSNP">p.M190T</text>
<line x1='1902.6' y1='5554.8' x2='1901.4' y2='5557.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1901.4' y1='5557.5' x2='1889.6' y2='5585.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1889.6' y1='5585.1' x2='1888.4' y2='5587.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1903.2" y="5595.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-66.8,1903.2,5595.3)" sift="0.02" id="M455T_rsID_rs1171652794_1_279" polyphen2="0.622" dbsource="dbSNP" ipvMAF="NA" class="mut">p.M455T</text>
<line x1='1617.8' y1='5027.1' x2='1616.1' y2='5029.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1616.1' y1='5029.6' x2='1599.2' y2='5054.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1599.2' y1='5054.4' x2='1597.6' y2='5056.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1611.1" y="5067.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-55.7,1611.1,5067.2)" id="M480V_rsID_rs1382719890_1_381" sift="0.01" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.649">p.M480V</text>
<line x1='3365.0' y1='5426.2' x2='3365.5' y2='5429.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3365.5' y1='5429.2' x2='3369.9' y2='5458.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3369.9' y1='5458.8' x2='3370.4' y2='5461.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3353.7" y="5465.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(81.4,3353.7,5465.3)" id="M383T_rsID_rs1396769231_1_391" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.999">p.M383T</text>
<line x1='4234.1' y1='5120.5' x2='4235.6' y2='5123.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4235.6' y1='5123.1' x2='4208.4' y2='5173.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4208.4' y1='5173.1' x2='4209.9' y2='5175.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4195.5" y="5184.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(60.9,4195.5,5184.8)" id="T334M_rsID_rs1471486893_1_435" sift="0.06" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.288">p.T334M</text>
<line x1='1761.7' y1='5118.1' x2='1760.2' y2='5120.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1760.2' y1='5120.7' x2='1745.0' y2='5146.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1745.0' y1='5146.6' x2='1743.5' y2='5149.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1757.7" y="5158.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-59.7,1757.7,5158.5)" sift="NA" id="D471D_rsID_rs200499668_1_13" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.D471D</text>
<line x1='5493.9' y1='1766.0' x2='5496.6' y2='1764.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5496.6' y1='1764.7' x2='5523.5' y2='1751.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5523.5' y1='1751.4' x2='5526.2' y2='1750.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5534.6" y="1764.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(333.7,5534.6,1764.8)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA" id="Q139Q_rsID_rs370485974_1_23" sift="NA">p.Q139Q</text>
<line x1='2499.8' y1='426.7' x2='2499.3' y2='423.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2499.3' y1='423.7' x2='2508.4' y2='391.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2508.4' y1='391.4' x2='2507.9' y2='388.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2491.0" y="390.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(79.3,2491.0,390.7)" sift="0" id="D785N_rsID_rs373153165_2_29" polyphen2="0.838" dbsource="dbSNP" ipvMAF="NA" class="mut">p.D785N</text>
<line x1='2203.3' y1='679.5' x2='2202.3' y2='676.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2202.3' y1='676.6' x2='2192.6' y2='648.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2192.6' y1='648.3' x2='2191.6' y2='645.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2175.2" y="650.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(71.1,2175.2,650.0)" id="D767H_rsID_rs747516757_1_47" sift="0.07" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.717">p.D767H</text>
<line x1='547.1' y1='2945.8' x2='544.1' y2='2945.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='544.1' y1='2945.8' x2='514.5' y2='2930.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='514.5' y1='2930.9' x2='511.5' y2='2930.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="510.0" y="2947.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(1.6,510.0,2947.8)" sift="0.46" id="D609N_rsID_rs747988885_1_48" polyphen2="0.003" class="mut" ipvMAF="NA" dbsource="dbSNP">p.D609N</text>
<line x1='4701.0' y1='4768.2' x2='4703.1' y2='4770.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4703.1' y1='4770.3' x2='4723.9' y2='4791.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4723.9' y1='4791.9' x2='4725.9' y2='4794.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4714.3" y="4806.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(46.1,4714.3,4806.6)" sift="0.9" id="D303N_rsID_rs749750821_1_54" polyphen2="0.012" dbsource="dbSNP" ipvMAF="0.000265" class="mut">p.D303N</text>
<line x1='3707.6' y1='5530.4' x2='3708.4' y2='5533.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3708.4' y1='5533.3' x2='3716.5' y2='5562.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3716.5' y1='5562.2' x2='3717.3' y2='5565.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3701.2" y="5570.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(74.4,3701.2,5570.6)" sift="NA" id="D367D_rsID_rs750477605_1_59" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.D367D</text>
<line x1='1223.0' y1='860.2' x2='1221.0' y2='857.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1221.0' y1='857.9' x2='1201.9' y2='834.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1201.9' y1='834.8' x2='1200.0' y2='832.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1186.3" y="842.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(50.3,1186.3,842.6)" sift="0.1" id="N720D_rsID_rs41303171_1_82" polyphen2="0.02" ipvMAF="0.004503" dbsource="dbSNP" class="mut">p.N720D</text>
<line x1='424.7' y1='2520.8' x2='421.7' y2='2520.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='421.7' y1='2520.3' x2='392.3' y2='2514.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='392.3' y1='2514.8' x2='389.3' y2='2514.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="385.3" y="2530.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(10.5,385.3,2530.8)" polyphen2="0.717" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0" id="D630H_rsID_rs140312271_1_86">p.D630H</text>
<line x1='1675.9' y1='5264.8' x2='1674.4' y2='5267.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1674.4' y1='5267.4' x2='1659.2' y2='5293.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1659.2' y1='5293.3' x2='1657.7' y2='5295.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1671.9" y="5305.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-59.7,1671.9,5305.3)" id="D471N_rsID_rs759033741_1_116" sift="0.27" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.04">p.D471N</text>
<line x1='659.7' y1='4170.0' x2='657.0' y2='4171.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='657.0' y1='4171.3' x2='630.1' y2='4184.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='630.1' y1='4184.7' x2='627.5' y2='4186.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="634.2" y="4201.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-26.6,634.2,4201.7)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.609" id="N546D_rsID_rs761944150_1_140" sift="0.02">p.N546D</text>
<line x1='3289.4' y1='5601.5' x2='3289.7' y2='5604.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3289.7' y1='5604.4' x2='3293.0' y2='5634.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3293.0' y1='5634.3' x2='3293.4' y2='5637.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3276.6" y="5640.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(83.7,3276.6,5640.1)" polyphen2="NA" dbsource="dbSNP" ipvMAF="0.000265" class="mut" sift="NA" id="Q388Q_rsID_rs773676270_1_189">p.Q388Q</text>
<line x1='549.6' y1='2074.1' x2='546.8' y2='2073.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='546.8' y1='2073.1' x2='518.7' y2='2062.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='518.7' y1='2062.5' x2='515.9' y2='2061.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="509.0" y="2077.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(20.7,509.0,2077.0)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="Q653Q_rsID_rs774412370_1_191">p.Q653Q</text>
<line x1='3935.5' y1='5446.8' x2='3936.5' y2='5449.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3936.5' y1='5449.6' x2='3947.2' y2='5477.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3947.2' y1='5477.6' x2='3948.3' y2='5480.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3932.8" y="5487.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(69.1,3932.8,5487.4)" sift="0" id="D355N_rsID_rs961360700_1_252" polyphen2="0.999" dbsource="dbSNP" ipvMAF="NA" class="mut">p.D355N</text>
<line x1='1000.0' y1='4421.1' x2='997.5' y2='4422.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='997.5' y1='4422.8' x2='973.1' y2='4440.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='973.1' y1='4440.2' x2='970.6' y2='4441.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="979.7" y="4456.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-35.4,979.7,4456.4)" sift="NA" id="Q526Q_rsID_rs1176549305_1_285" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.Q526Q</text>
<line x1='831.4' y1='4147.6' x2='828.8' y2='4149.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='828.8' y1='4149.0' x2='802.2' y2='4163.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='802.2' y1='4163.0' x2='799.6' y2='4164.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="806.7" y="4179.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-27.9,806.7,4179.9)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="D543D_rsID_rs1178831057_1_286">p.D543D</text>
<line x1='4211.5' y1='5322.5' x2='4212.9' y2='5325.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4212.9' y1='5325.2' x2='4219.1' y2='5355.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4219.1' y1='5355.8' x2='4220.5' y2='5358.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4205.8" y="5367.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(62.6,4205.8,5367.1)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="Q340Q_rsID_rs1181373965_1_288">p.Q340Q</text>
<line x1='3732.6' y1='5699.9' x2='3733.4' y2='5702.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3733.4' y1='5702.8' x2='3741.2' y2='5731.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3741.2' y1='5731.7' x2='3742.0' y2='5734.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3725.9" y="5740.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(74.8,3725.9,5740.0)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.08" id="D368N_rsID_rs1228750646_1_308" sift="0.07">p.D368N</text>
<line x1='1336.8' y1='4803.7' x2='1334.7' y2='4805.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1334.7' y1='4805.9' x2='1314.4' y2='4828.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1314.4' y1='4828.0' x2='1312.4' y2='4830.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1324.2" y="4842.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-47.3,1324.2,4842.4)" sift="NA" id="D499D_rsID_rs1246309926_1_317" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.D499D</text>
<line x1='4844.6' y1='4617.7' x2='4846.9' y2='4619.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4846.9' y1='4619.7' x2='4860.0' y2='4650.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4860.0' y1='4650.1' x2='4862.3' y2='4652.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4851.7" y="4665.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(41.6,4851.7,4665.5)" sift="0" id="D292N_rsID_rs1248745003_1_319" polyphen2="0.995" dbsource="dbSNP" ipvMAF="NA" class="mut">p.D292N</text>
<line x1='5777.5' y1='2987.0' x2='5780.5' y2='2987.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5780.5' y1='2987.0' x2='5810.5' y2='2986.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5810.5' y1='2986.9' x2='5813.5' y2='2986.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5814.5" y="3003.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(359.7,5814.5,3003.9)" sift="0.02" id="D198N_rsID_rs1345857521_1_368" polyphen2="0.914" class="mut" ipvMAF="NA" dbsource="dbSNP">p.D198N</text>
<line x1='1095.0' y1='4798.0' x2='1092.8' y2='4800.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1092.8' y1='4800.1' x2='1071.0' y2='4820.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1071.0' y1='4820.7' x2='1068.8' y2='4822.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1079.8" y="4835.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-43.3,1079.8,4835.7)" polyphen2="0.382" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.23" id="N508D_rsID_rs1349942475_1_369">p.N508D</text>
<line x1='3101.6' y1='5451.4' x2='3101.7' y2='5454.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3101.7' y1='5454.4' x2='3102.9' y2='5484.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3102.9' y1='5484.4' x2='3103.0' y2='5487.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3086.1" y="5489.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(87.6,3086.1,5489.0)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="1" id="N397D_rsID_rs1365935088_1_376" sift="0">p.N397D</text>
<line x1='225.0' y1='2810.1' x2='222.0' y2='2809.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='222.0' y1='2809.9' x2='189.9' y2='2842.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='189.9' y1='2842.2' x2='186.9' y2='2842.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="185.0" y="2859.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(3.2,185.0,2859.0)" id="D615H_rsID_rs1408702726_1_398" sift="0.02" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.263">p.D615H</text>
<line x1='257.6' y1='2489.7' x2='254.6' y2='2489.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='254.6' y1='2489.2' x2='225.1' y2='2483.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='225.1' y1='2483.7' x2='222.2' y2='2483.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="218.1" y="2499.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(10.5,218.1,2499.7)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="D630D_rsID_rs1433836817_1_411">p.D630D</text>
<line x1='5335.5' y1='3751.7' x2='5338.4' y2='3752.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5338.4' y1='3752.6' x2='5366.9' y2='3761.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5366.9' y1='3761.8' x2='5369.8' y2='3762.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5365.5" y="3779.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(17.8,5365.5,3779.2)" polyphen2="0.006" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0.75" id="H239Q_rsID_rs1448326240_1_422">p.H239Q</text>
<line x1='1076.3' y1='1477.2' x2='1074.0' y2='1475.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1074.0' y1='1475.3' x2='1070.7' y2='1431.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1070.7' y1='1431.4' x2='1068.4' y2='1429.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1057.0" y="1442.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(39.1,1057.0,1442.1)" id="D693H_rsID_rs1462355609_1_429" sift="0.01" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.372">p.D693H</text>
<line x1='4266.6' y1='5101.3' x2='4268.2' y2='5103.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4268.2' y1='5103.8' x2='4283.7' y2='5129.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4283.7' y1='5129.5' x2='4285.2' y2='5132.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4271.2" y="5141.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(58.9,4271.2,5141.7)" sift="0.02" id="M332L_rsID_rs185525294_1_1" polyphen2="0.428" class="mut" dbsource="dbSNP" ipvMAF="0.000265">p.M332L</text>
<line x1='2352.8' y1='5366.6' x2='2352.0' y2='5369.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2352.0' y1='5369.5' x2='2344.1' y2='5398.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2344.1' y1='5398.4' x2='2343.3' y2='5401.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2359.4" y="5406.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-74.7,2359.4,5406.7)" dbsource="dbSNP" ipvMAF="0.000265" class="mut" polyphen2="NA" id="N437N_rsID_rs199569050_1_3" sift="NA">p.N437N</text>
<line x1='1041.6' y1='1522.0' x2='1039.2' y2='1520.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1039.2' y1='1520.2' x2='1023.8' y2='1490.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1023.8' y1='1490.9' x2='1021.5' y2='1489.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1010.4" y="1502.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(37.4,1010.4,1502.0)" dbsource="dbSNP" ipvMAF="0.02252" class="mut" polyphen2="NA" id="N690N_rsID_rs4646179_1_69" sift="NA">p.N690N</text>
<line x1='4940.4' y1='1238.8' x2='4942.7' y2='1236.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4942.7' y1='1236.8' x2='4964.9' y2='1216.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4964.9' y1='1216.6' x2='4967.1' y2='1214.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4979.2" y="1226.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(317.8,4979.2,1226.6)" id="N103H_rsID_rs143158922_1_97" sift="0.51" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.623">p.N103H</text>
<line x1='3532.3' y1='5395.1' x2='3533.0' y2='5398.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3533.0' y1='5398.0' x2='3539.5' y2='5427.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3539.5' y1='5427.3' x2='3540.1' y2='5430.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3523.8" y="5434.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(77.5,3523.8,5434.8)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="H374H_rsID_rs757578476_1_111" sift="NA">p.H374H</text>
<line x1='4994.3' y1='4695.3' x2='4996.6' y2='4697.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4996.6' y1='4697.3' x2='5019.4' y2='4716.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5019.4' y1='4716.7' x2='5021.7' y2='4718.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5011.4" y="4732.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(40.4,5011.4,4732.2)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.892" id="N290H_rsID_rs763994205_1_145" sift="0.02">p.N290H</text>
<line x1='5620.5' y1='2927.1' x2='5623.5' y2='2927.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5623.5' y1='2927.1' x2='5653.5' y2='2926.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5653.5' y1='2926.2' x2='5656.5' y2='2926.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5657.9" y="2943.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(358.4,5657.9,2943.1)" sift="0" id="H195N_rsID_rs764661406_2_149" polyphen2="0.33" class="mut" ipvMAF="NA" dbsource="dbSNP">p.H195N</text>
<line x1='4897.8' y1='4798.4' x2='4899.9' y2='4800.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4899.9' y1='4800.4' x2='4921.7' y2='4821.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4921.7' y1='4821.1' x2='4923.9' y2='4823.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4912.9" y="4836.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(43.5,4912.9,4836.1)" sift="0.06" id="M297L_rsID_rs772143709_1_183" polyphen2="0.089" class="mut" dbsource="dbSNP" ipvMAF="NA">p.M297L</text>
<line x1='480.9' y1='2285.3' x2='478.0' y2='2284.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='478.0' y1='2284.4' x2='449.2' y2='2276.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='449.2' y1='2276.3' x2='446.3' y2='2275.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="440.8" y="2291.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(15.8,440.8,2291.5)" id="L642M_rsID_rs868528474_1_232" sift="0.03" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.97">p.L642M</text>
<line x1='550.2' y1='3134.9' x2='547.2' y2='3135.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='547.2' y1='3135.1' x2='517.3' y2='3136.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='517.3' y1='3136.7' x2='514.3' y2='3136.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="514.3" y="3153.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-3.2,514.3,3153.9)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.998" id="N599K_rsID_rs1162138115_1_275" sift="0.01">p.N599K</text>
<line x1='5036.1' y1='4651.3' x2='5038.4' y2='4653.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5038.4' y1='4653.2' x2='5061.7' y2='4672.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5061.7' y1='4672.1' x2='5064.0' y2='4673.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5054.1" y="4687.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(39.0,5054.1,4687.7)" sift="0.58" id="Q287K_rsID_rs1165212018_1_276" polyphen2="0.003" dbsource="dbSNP" ipvMAF="NA" class="mut">p.Q287K</text>
<line x1='3787.2' y1='5323.8' x2='3788.2' y2='5326.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3788.2' y1='5326.6' x2='3797.8' y2='5355.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3797.8' y1='5355.0' x2='3798.8' y2='5357.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3783.0" y="5364.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(71.3,3783.0,5364.2)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.966" id="M360L_rsID_rs1205410066_1_298" sift="0.01">p.M360L</text>
<line x1='5390.8' y1='3551.2' x2='5393.7' y2='3551.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5393.7' y1='3551.9' x2='5422.9' y2='3558.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5422.9' y1='3558.6' x2='5425.9' y2='3559.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5423.0" y="3576.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(13.0,5423.0,3576.1)" sift="NA" id="H228H_rsID_rs1231367923_1_315" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.H228H</text>
<line x1='631.0' y1='3638.2' x2='628.1' y2='3639.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='628.1' y1='3639.0' x2='599.1' y2='3646.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='599.1' y1='3646.8' x2='596.2' y2='3647.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="599.7" y="3664.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-15.1,599.7,3664.2)" sift="NA" id="N572N_rsID_rs1266676599_1_329" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.N572N</text>
<line x1='2308.2' y1='5529.6' x2='2307.4' y2='5532.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2307.4' y1='5532.5' x2='2299.5' y2='5561.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2299.5' y1='5561.4' x2='2298.7' y2='5564.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2314.9" y="5569.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-74.7,2314.9,5569.7)" sift="0" id="N437H_rsID_rs1314469120_1_349" polyphen2="1" class="mut" ipvMAF="NA" dbsource="dbSNP">p.N437H</text>
<line x1='440.8' y1='2400.2' x2='437.9' y2='2399.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='437.9' y1='2399.5' x2='408.7' y2='2392.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='408.7' y1='2392.7' x2='405.8' y2='2392.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="401.0" y="2408.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(13.2,401.0,2408.3)" sift="NA" id="N636N_rsID_rs1315819425_1_351" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.N636N</text>
<line x1='5065.6' y1='1125.2' x2='5067.8' y2='1123.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5067.8' y1='1123.2' x2='5090.0' y2='1103.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5090.0' y1='1103.1' x2='5092.2' y2='1101.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5104.4" y="1113.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(317.8,5104.4,1113.0)" id="N103N_rsID_rs1338694035_1_359" sift="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA">p.N103N</text>
<line x1='1503.1' y1='5159.4' x2='1501.4' y2='5161.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1501.4' y1='5161.9' x2='1484.3' y2='5186.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1484.3' y1='5186.5' x2='1482.6' y2='5189.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1496.0" y="5199.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-55.3,1496.0,5199.5)" polyphen2="0.999" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.02" id="K481N_rsID_rs1411114707_1_400">p.K481N</text>
<line x1='5309.9' y1='2172.9' x2='5312.7' y2='2171.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5312.7' y1='2171.9' x2='5340.9' y2='2161.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5340.9' y1='2161.8' x2='5343.8' y2='2160.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5350.4" y="2176.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(340.3,5350.4,2176.4)" sift="0.32" id="N154K_rsID_rs1435872603_1_414" polyphen2="0.007" class="mut" dbsource="dbSNP" ipvMAF="NA">p.N154K</text>
<line x1='1572.9' y1='809.4' x2='1571.2' y2='806.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1571.2' y1='806.9' x2='1554.8' y2='781.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1554.8' y1='781.7' x2='1553.2' y2='779.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1538.4" y="787.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(56.9,1538.4,787.7)" id="N735K_rsID_rs1445361759_1_418" sift="0.05" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0">p.N735K</text>
<line x1='596.1' y1='3491.0' x2='593.2' y2='3491.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='593.2' y1='3491.6' x2='563.8' y2='3497.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='563.8' y1='3497.6' x2='560.9' y2='3498.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="563.3" y="3515.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-11.5,563.3,3515.1)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="N580N_rsID_rs1447811956_1_419">p.N580N</text>
<line x1='2499.9' y1='5402.0' x2='2499.3' y2='5404.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2499.3' y1='5404.9' x2='2493.2' y2='5434.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2493.2' y1='5434.3' x2='2492.5' y2='5437.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2509.0" y="5441.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-78.2,2509.0,5441.6)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.011" id="Q429K_rsID_rs1454617025_1_425" sift="0.8">p.Q429K</text>
<line x1='5092.4' y1='1427.4' x2='5094.8' y2='1425.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5094.8' y1='1425.6' x2='5118.8' y2='1407.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5118.8' y1='1407.6' x2='5121.2' y2='1405.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5132.2" y="1418.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(323.1,5132.2,1418.8)" sift="0.01" id="R115Q_rsID_rs201900069_2_16" polyphen2="0.743" dbsource="dbSNP" ipvMAF="0.000265" class="mut">p.R115Q</text>
<line x1='5400.7' y1='4048.0' x2='5403.5' y2='4049.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5403.5' y1='4049.2' x2='5431.0' y2='4061.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5431.0' y1='4061.2' x2='5433.7' y2='4062.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5427.8" y="4078.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(23.6,5427.8,4078.4)" sift="0" id="Y252N_rsID_rs371464495_1_21" polyphen2="1" ipvMAF="NA" dbsource="dbSNP" class="mut">p.Y252N</text>
<line x1='2531.9' y1='591.6' x2='2531.3' y2='588.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2531.3' y1='588.6' x2='2539.5' y2='556.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2539.5' y1='556.5' x2='2539.0' y2='553.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2522.1" y="555.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(79.3,2522.1,555.8)" polyphen2="0.838" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="D785Y_rsID_rs373153165_1_29">p.D785Y</text>
<line x1='1860.9' y1='5173.1' x2='1859.6' y2='5175.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1859.6' y1='5175.7' x2='1845.6' y2='5202.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1845.6' y1='5202.3' x2='1844.2' y2='5205.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1858.9" y="5213.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-62.3,1858.9,5213.7)" sift="NA" id="K465K_rsID_rs746405119_1_45" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.K465K</text>
<line x1='1389.2' y1='5286.0' x2='1387.4' y2='5288.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1387.4' y1='5288.4' x2='1370.2' y2='5312.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1370.2' y1='5312.9' x2='1368.4' y2='5315.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1381.8" y="5326.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-54.8,1381.8,5326.0)" id="R482Q_rsID_rs748359955_1_51" sift="0.27" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.969">p.R482Q</text>
<line x1='557.3' y1='1665.5' x2='554.6' y2='1664.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='554.6' y1='1664.0' x2='528.3' y2='1649.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='528.3' y1='1649.6' x2='525.7' y2='1648.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="516.7" y="1662.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(28.6,516.7,1662.7)" sift="0.2" id="R671Q_rsID_rs753705431_2_71" polyphen2="0.334" class="mut" ipvMAF="NA" dbsource="dbSNP">p.R671Q</text>
<line x1='605.3' y1='4061.7' x2='602.6' y2='4063.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='602.6' y1='4063.0' x2='575.2' y2='4075.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='575.2' y1='4075.1' x2='572.4' y2='4076.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="578.4" y="4092.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-23.9,578.4,4092.3)" sift="0.13" id="Q552R_rsID_rs112493570_1_85" polyphen2="0.105" dbsource="dbSNP" ipvMAF="NA" class="mut">p.Q552R</text>
<line x1='559.1' y1='3248.0' x2='556.1' y2='3248.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='556.1' y1='3248.3' x2='526.2' y2='3251.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='526.2' y1='3251.4' x2='523.3' y2='3251.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="524.0" y="3268.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-5.8,524.0,3268.7)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.006" id="T593N_rsID_rs140857723_1_93" sift="0.56">p.T593N</text>
<line x1='5449.5' y1='3139.8' x2='5452.5' y2='3140.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5452.5' y1='3140.0' x2='5482.5' y2='3141.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5482.5' y1='3141.7' x2='5485.5' y2='3141.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5485.4" y="3158.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(3.3,5485.4,3158.9)" polyphen2="0.027" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.43" id="D206G_rsID_rs142443432_1_94">p.D206G</text>
<line x1='924.7' y1='4598.4' x2='922.3' y2='4600.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='922.3' y1='4600.2' x2='898.6' y2='4618.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='898.6' y1='4618.5' x2='896.2' y2='4620.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="905.8" y="4634.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-37.6,905.8,4634.4)" sift="0" id="Y521H_rsID_rs759200680_1_120" polyphen2="0.973" dbsource="dbSNP" ipvMAF="NA" class="mut">p.Y521H</text>
<line x1='5595.0' y1='3350.1' x2='5598.0' y2='3350.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5598.0' y1='3350.5' x2='5627.7' y2='3354.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5627.7' y1='3354.5' x2='5630.7' y2='3354.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5629.3" y="3371.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(7.7,5629.3,3371.9)" id="D216Y_rsID_rs761269389_1_128" sift="0.03" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.298">p.D216Y</text>
<line x1='4905.6' y1='4545.4' x2='4907.9' y2='4547.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4907.9' y1='4547.3' x2='4931.2' y2='4566.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4931.2' y1='4566.2' x2='4933.5' y2='4568.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4923.6" y="4581.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(39.0,4923.6,4581.9)" sift="0.12" id="Q287R_rsID_rs763264372_1_141" polyphen2="0.105" class="mut" dbsource="dbSNP" ipvMAF="NA">p.Q287R</text>
<line x1='5452.6' y1='2931.8' x2='5455.6' y2='2931.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5455.6' y1='2931.7' x2='5485.5' y2='2930.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5485.5' y1='2930.9' x2='5488.5' y2='2930.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5490.0" y="2947.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(358.4,5490.0,2947.8)" polyphen2="0.33" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="H195Y_rsID_rs764661406_1_149">p.H195Y</text>
<line x1='1407.5' y1='4866.5' x2='1405.6' y2='4868.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1405.6' y1='4868.7' x2='1386.1' y2='4891.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1386.1' y1='4891.6' x2='1384.2' y2='4893.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1396.5" y="4905.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-49.5,1396.5,4905.6)" polyphen2="0.952" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.01" id="D494V_rsID_rs765152220_1_153">p.D494V</text>
<line x1='261.8' y1='3428.5' x2='258.9' y2='3429.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='258.9' y1='3429.0' x2='229.2' y2='3433.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='229.2' y1='3433.6' x2='226.3' y2='3434.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="227.9" y="3451.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-8.9,227.9,3451.0)" sift="0" id="N586Y_rsID_rs768685219_1_165" polyphen2="0.519" class="mut" dbsource="dbSNP" ipvMAF="NA">p.N586Y</text>
<line x1='1264.9' y1='1265.4' x2='1262.7' y2='1263.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1262.7' y1='1263.3' x2='1241.5' y2='1242.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1241.5' y1='1242.0' x2='1239.4' y2='1239.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1226.7" y="1251.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(45.0,1226.7,1251.3)" id="R708Q_rsID_rs769062069_1_169" sift="0" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.935">p.R708Q</text>
<line x1='225.0' y1='2810.1' x2='222.0' y2='2809.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='222.0' y1='2809.9' x2='192.1' y2='2807.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='192.1' y1='2807.8' x2='189.1' y2='2807.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="187.0" y="2824.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(3.9,187.0,2824.5)" sift="0.21" id="D615G_rsID_rs773083611_1_185" polyphen2="0.003" dbsource="dbSNP" ipvMAF="NA" class="mut">p.D615G</text>
<line x1='4973.5' y1='4958.7' x2='4975.6' y2='4960.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4975.6' y1='4960.8' x2='4996.9' y2='4981.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4996.9' y1='4981.9' x2='4999.0' y2='4984.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4987.7" y="4996.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(44.8,4987.7,4996.8)" sift="0" id="Q300R_rsID_rs773936807_1_193" polyphen2="0.904" ipvMAF="NA" dbsource="dbSNP" class="mut">p.Q300R</text>
<line x1='4664.0' y1='5020.5' x2='4665.9' y2='5022.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4665.9' y1='5022.8' x2='4685.0' y2='5046.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4685.0' y1='5046.0' x2='4686.9' y2='5048.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4674.4" y="5059.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(50.5,4674.4,5059.8)" sift="NA" id="K313K_rsID_rs775440758_1_200" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.K313K</text>
<line x1='4806.7' y1='4660.0' x2='4808.9' y2='4662.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4808.9' y1='4662.0' x2='4831.0' y2='4682.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4831.0' y1='4682.3' x2='4833.2' y2='4684.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4822.4" y="4697.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(42.6,4822.4,4697.5)" polyphen2="0.02" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.1" id="D295G_rsID_rs776226831_1_207">p.D295G</text>
<line x1='1190.0' y1='4656.4' x2='1187.8' y2='4658.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1187.8' y1='4658.4' x2='1165.6' y2='4678.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1165.6' y1='4678.6' x2='1163.4' y2='4680.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1174.2" y="4693.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-42.5,1174.2,4693.8)" class="mut" dbsource="dbSNP" ipvMAF="0.000265" polyphen2="0.979" id="Y510H_rsID_rs779199005_1_217" sift="0.01">p.Y510H</text>
<line x1='819.9' y1='1274.2' x2='817.6' y2='1272.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='817.6' y1='1272.3' x2='794.0' y2='1253.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='794.0' y1='1253.7' x2='791.7' y2='1251.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="780.4" y="1264.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(38.4,780.4,1264.6)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.055" id="D693G_rsID_rs781544129_1_225" sift="0.03">p.D693G</text>
<line x1='5727.5' y1='2454.5' x2='5730.4' y2='2453.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5730.4' y1='2453.9' x2='5762.5' y2='2461.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5762.5' y1='2461.6' x2='5765.5' y2='2461.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5769.6" y="2477.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(349.0,5769.6,2477.5)" id="G173D_rsID_rs865852627_1_228" sift="0" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.991">p.G173D</text>
<line x1='1139.8' y1='4599.8' x2='1137.5' y2='4601.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1137.5' y1='4601.7' x2='1114.8' y2='4621.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1114.8' y1='4621.3' x2='1112.5' y2='4623.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1122.9" y="4636.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-40.7,1122.9,4636.7)" id="R514Q_rsID_rs868506911_1_231" sift="0.01" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.995">p.R514Q</text>
<line x1='2457.9' y1='607.1' x2='2457.2' y2='604.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2457.2' y1='604.2' x2='2450.6' y2='575.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2450.6' y1='575.0' x2='2449.9' y2='572.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2433.1" y="574.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(77.2,2433.1,574.9)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.8" id="Y781H_rsID_rs902013280_1_241" sift="0.04">p.Y781H</text>
<line x1='1364.8' y1='4829.1' x2='1362.8' y2='4831.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1362.8' y1='4831.4' x2='1342.8' y2='4853.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1342.8' y1='4853.7' x2='1340.8' y2='4856.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1352.8" y="4868.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-48.2,1352.8,4868.0)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.874" id="Y497H_rsID_rs961921482_1_251" sift="0.29">p.Y497H</text>
<line x1='5334.3' y1='2244.5' x2='5337.1' y2='2243.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5337.1' y1='2243.6' x2='5365.7' y2='2234.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5365.7' y1='2234.3' x2='5368.5' y2='2233.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5374.7" y="2249.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(342.1,5374.7,2249.3)" sift="0.02" id="Y158H_rsID_rs984704647_1_258" polyphen2="0.996" class="mut" dbsource="dbSNP" ipvMAF="NA">p.Y158H</text>
<line x1='1753.1' y1='5470.7' x2='1751.8' y2='5473.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1751.8' y1='5473.4' x2='1738.2' y2='5500.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1738.2' y1='5500.2' x2='1736.9' y2='5502.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1751.6" y="5511.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-63.2,1751.6,5511.3)" polyphen2="0.991" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="V463D_rsID_rs1169303958_1_278">p.V463D</text>
<line x1='2467.4' y1='259.8' x2='2466.8' y2='256.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2466.8' y1='256.8' x2='2474.7' y2='224.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2474.7' y1='224.8' x2='2474.1' y2='221.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2457.2" y="224.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(79.3,2457.2,224.1)" sift="0" id="D785A_rsID_rs1248729689_1_318" polyphen2="0.017" class="mut" ipvMAF="NA" dbsource="dbSNP">p.D785A</text>
<line x1='5618.5' y1='3008.0' x2='5621.5' y2='3008.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5621.5' y1='3008.0' x2='5651.4' y2='3021.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5651.4' y1='3021.0' x2='5654.4' y2='3021.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5655.2" y="3038.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(0.5,5655.2,3038.1)" polyphen2="0.52" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.15" id="Y199H_rsID_rs1277079227_1_333">p.Y199H</text>
<line x1='2474.9' y1='5732.5' x2='2474.3' y2='5735.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2474.3' y1='5735.4' x2='2468.7' y2='5764.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2468.7' y1='5764.9' x2='2468.1' y2='5767.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2484.6" y="5772.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-79.1,2484.6,5772.0)" polyphen2="0.923" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="D427Y_rsID_rs1316056737_1_352">p.D427Y</text>
<line x1='2737.6' y1='560.6' x2='2737.2' y2='557.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2737.2' y1='557.6' x2='2734.0' y2='527.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2734.0' y1='527.8' x2='2733.7' y2='524.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2716.7" y="525.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(83.9,2716.7,525.7)" polyphen2="0.218" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0.05" id="Q796R_rsID_rs1355591379_1_373">p.Q796R</text>
<line x1='1571.5' y1='5400.7' x2='1570.0' y2='5403.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1570.0' y1='5403.2' x2='1554.7' y2='5429.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1554.7' y1='5429.0' x2='1553.1' y2='5431.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1567.3" y="5441.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-59.2,1567.3,5441.1)" id="Q472R_rsID_rs1366555470_1_378" sift="0.34" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.223">p.Q472R</text>
<line x1='1269.8' y1='1042.6' x2='1267.8' y2='1040.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1267.8' y1='1040.4' x2='1247.9' y2='1017.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1247.9' y1='1017.9' x2='1245.9' y2='1015.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1232.5" y="1026.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(48.5,1232.5,1026.2)" id="R716H_rsID_rs200540199_1_14" sift="0.08" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.277">p.R716H</text>
<line x1='1291.8' y1='1238.8' x2='1289.7' y2='1236.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1289.7' y1='1236.7' x2='1279.0' y2='1205.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1279.0' y1='1205.3' x2='1277.0' y2='1203.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1264.0" y="1214.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(46.2,1264.0,1214.2)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.999" id="R710H_rsID_rs370187012_1_20" sift="0">p.R710H</text>
<line x1='5126.6' y1='1477.4' x2='5129.0' y2='1475.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5129.0' y1='1475.6' x2='5158.5' y2='1465.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5158.5' y1='1465.2' x2='5160.9' y2='1463.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5171.5" y="1476.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(324.6,5171.5,1476.8)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="T118T_rsID_rs754488878_1_72">p.T118T</text>
<line x1='3521.2' y1='5741.4' x2='3521.7' y2='5744.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3521.7' y1='5744.3' x2='3527.3' y2='5773.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3527.3' y1='5773.8' x2='3527.9' y2='5776.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3511.4" y="5780.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(79.2,3511.4,5780.9)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="1" id="H378R_rsID_rs142984500_1_96" sift="0">p.H378R</text>
<line x1='5585.2' y1='3409.8' x2='5588.2' y2='3410.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5588.2' y1='3410.3' x2='5617.8' y2='3415.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5617.8' y1='3415.0' x2='5620.8' y2='3415.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5619.0" y="3432.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(9.0,5619.0,3432.4)" polyphen2="0.926" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="R219H_rsID_rs759590772_1_126">p.R219H</text>
<line x1='2208.2' y1='5322.2' x2='2207.2' y2='5325.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2207.2' y1='5325.0' x2='2197.5' y2='5353.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2197.5' y1='5353.4' x2='2196.5' y2='5356.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2211.9" y="5362.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-71.2,2211.9,5362.5)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="T445T_rsID_rs761297461_1_129" sift="NA">p.T445T</text>
<line x1='3286.8' y1='5772.7' x2='3287.1' y2='5775.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3287.1' y1='5775.7' x2='3290.2' y2='5805.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3290.2' y1='5805.5' x2='3290.5' y2='5808.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3273.7" y="5811.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(84.1,3273.7,5811.2)" polyphen2="0.827" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.02" id="P389H_rsID_rs762890235_1_143">p.P389H</text>
<line x1='443.1' y1='4110.2' x2='440.4' y2='4111.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='440.4' y1='4111.4' x2='412.8' y2='4123.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='412.8' y1='4123.3' x2='410.1' y2='4124.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="416.0" y="4140.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-23.5,416.0,4140.5)" sift="0.11" id="K553T_rsID_rs899455705_1_239" polyphen2="0.104" class="mut" ipvMAF="NA" dbsource="dbSNP">p.K553T</text>
<line x1='2407.7' y1='5380.9' x2='2407.0' y2='5383.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2407.0' y1='5383.8' x2='2399.7' y2='5413.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2399.7' y1='5413.0' x2='2399.0' y2='5415.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2415.3" y="5420.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-76.0,2415.3,5420.9)" sift="NA" id="T434T_rsID_rs918930523_1_243" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.T434T</text>
<line x1='1037.5' y1='4940.0' x2='1035.4' y2='4942.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1035.4' y1='4942.1' x2='1002.9' y2='4951.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1002.9' y1='4951.8' x2='1000.8' y2='4953.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1012.0" y="4966.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-44.3,1012.0,4966.8)" sift="0" id="H505R_rsID_rs1016409802_1_261" polyphen2="1" dbsource="dbSNP" ipvMAF="NA" class="mut">p.H505R</text>
<line x1='2646.2' y1='5744.8' x2='2645.8' y2='5747.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2645.8' y1='5747.8' x2='2642.0' y2='5777.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2642.0' y1='5777.5' x2='2641.6' y2='5780.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2658.3" y="5783.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-82.7,2658.3,5783.6)" sift="0.08" id="K419T_rsID_rs1209307377_1_301" polyphen2="0.74" ipvMAF="NA" dbsource="dbSNP" class="mut">p.K419T</text>
<line x1='4400.6' y1='5406.6' x2='4402.1' y2='5409.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4402.1' y1='5409.2' x2='4403.3' y2='5443.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4403.3' y1='5443.2' x2='4404.8' y2='5445.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4390.5" y="5455.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(60.1,4390.5,5455.1)" sift="NA" id="T334T_rsID_rs1306455142_1_346" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.T334T</text>
<line x1='3569.0' y1='5560.0' x2='3569.7' y2='5563.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3569.7' y1='5563.0' x2='3576.2' y2='5592.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3576.2' y1='5592.2' x2='3576.8' y2='5595.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3560.4" y="5599.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(77.5,3560.4,5599.8)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="1" id="H374R_rsID_rs1309363592_1_348" sift="0">p.H374R</text>
<line x1='4804.0' y1='1337.1' x2='4806.2' y2='1335.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4806.2' y1='1335.1' x2='4828.3' y2='1314.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4828.3' y1='1314.7' x2='4830.5' y2='1312.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4842.7" y="1324.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(317.3,4842.7,1324.6)" sift="0.04" id="Q102P_rsID_rs1395878099_1_390" polyphen2="0.024" class="mut" dbsource="dbSNP" ipvMAF="NA">p.Q102P</text>
<line x1='1103.3' y1='4556.3' x2='1101.0' y2='4558.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1101.0' y1='4558.2' x2='1071.4' y2='4569.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1071.4' y1='4569.4' x2='1069.0' y2='4571.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1079.0" y="4585.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-39.1,1079.0,4585.1)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="T517T_rsID_rs1406026054_1_395">p.T517T</text>
<line x1='1489.5' y1='866.0' x2='1487.8' y2='863.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1487.8' y1='863.5' x2='1470.4' y2='839.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1470.4' y1='839.1' x2='1468.7' y2='836.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1454.3" y="845.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(54.7,1454.3,845.7)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.999" id="T730K_rsID_rs1421749672_1_405" sift="0">p.T730K</text>
<line x1='1393.0' y1='729.7' x2='1391.3' y2='727.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1391.3' y1='727.2' x2='1374.0' y2='702.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1374.0' y1='702.7' x2='1372.2' y2='700.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1357.8" y="709.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(54.7,1357.8,709.3)" id="T730T_rsID_rs1444714998_1_416" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.T730T</text>
<line x1='389.3' y1='2841.6' x2='386.3' y2='2841.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='386.3' y1='2841.4' x2='356.4' y2='2839.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='356.4' y1='2839.6' x2='353.4' y2='2839.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="351.4" y="2856.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(3.5,351.4,2856.3)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0" id="A614T_rsID_rs201715513_2_7" sift="1">p.A614T</text>
<line x1='3893.8' y1='5284.9' x2='3894.9' y2='5287.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3894.9' y1='5287.7' x2='3905.8' y2='5315.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3905.8' y1='5315.6' x2='3906.9' y2='5318.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3891.4" y="5325.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(68.6,3891.4,5325.5)" id="G354G_rsID_rs200909433_1_8" sift="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA">p.G354G</text>
<line x1='1495.5' y1='4938.1' x2='1493.7' y2='4940.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1493.7' y1='4940.5' x2='1475.3' y2='4964.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1475.3' y1='4964.2' x2='1473.5' y2='4966.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1486.3" y="4977.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-52.2,1486.3,4977.7)" polyphen2="0.061" class="mut" dbsource="dbSNP" ipvMAF="0.000265" sift="0.18" id="V488A_rsID_rs200973492_1_9">p.V488A</text>
<line x1='1079.0' y1='5019.9' x2='1076.9' y2='5022.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1076.9' y1='5022.1' x2='1056.3' y2='5043.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1056.3' y1='5043.8' x2='1054.2' y2='5046.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1065.9" y="5058.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-46.4,1065.9,5058.4)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="A501A_rsID_rs368996871_1_19">p.A501A</text>
<line x1='4047.8' y1='5561.5' x2='4049.0' y2='5564.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4049.0' y1='5564.2' x2='4060.3' y2='5592.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4060.3' y1='5592.0' x2='4061.5' y2='5594.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4046.1" y="5602.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(67.8,4046.1,5602.1)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.997" id="G352V_rsID_rs370610075_1_24" sift="0.03">p.G352V</text>
<line x1='4693.0' y1='4992.3' x2='4695.0' y2='4994.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4695.0' y1='4994.6' x2='4714.4' y2='5017.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4714.4' y1='5017.5' x2='4716.3' y2='5019.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4704.0" y="5031.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(49.6,4704.0,5031.5)" id="A311A_rsID_rs373974232_1_32" sift="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA">p.A311A</text>
<line x1='4800.5' y1='5118.8' x2='4802.5' y2='5121.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4802.5' y1='5121.1' x2='4821.9' y2='5144.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4821.9' y1='5144.0' x2='4823.8' y2='5146.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4811.5" y="5158.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(49.6,4811.5,5158.0)" sift="NA" id="A311A_rsID_rs373974232_2_32" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.A311A</text>
<line x1='2343.9' y1='469.1' x2='2343.2' y2='466.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2343.2' y1='466.2' x2='2344.0' y2='435.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2344.0' y1='435.1' x2='2343.3' y2='432.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2326.6" y="435.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(75.7,2326.6,435.4)" sift="NA" id="G777G_rsID_rs375252585_1_34" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.G777G</text>
<line x1='5291.6' y1='3876.6' x2='5294.4' y2='3877.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5294.4' y1='3877.7' x2='5322.4' y2='3888.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5322.4' y1='3888.4' x2='5325.2' y2='3889.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5320.0" y="3905.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(20.9,5320.0,3905.7)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="A246A_rsID_rs563087491_1_39">p.A246A</text>
<line x1='422.2' y1='2581.8' x2='419.2' y2='2581.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='419.2' y1='2581.3' x2='389.6' y2='2576.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='389.6' y1='2576.5' x2='386.7' y2='2576.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="383.0" y="2592.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(9.2,383.0,2592.7)" id="A627V_rsID_rs748163894_1_50" sift="0" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.713">p.A627V</text>
<line x1='5405.9' y1='2518.8' x2='5408.8' y2='2518.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5408.8' y1='2518.3' x2='5441.0' y2='2526.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5441.0' y1='2526.3' x2='5443.9' y2='2525.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5448.1" y="2542.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(349.0,5448.1,2542.2)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="G173G_rsID_rs751083544_1_57">p.G173G</text>
<line x1='1056.2' y1='4497.1' x2='1053.8' y2='4498.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1053.8' y1='4498.9' x2='1030.1' y2='4517.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1030.1' y1='4517.2' x2='1027.7' y2='4519.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1037.3" y="4533.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-37.6,1037.3,4533.1)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="Y521Y_rsID_rs751987956_1_64" sift="NA">p.Y521Y</text>
<line x1='1521.5' y1='1042.1' x2='1519.6' y2='1039.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1519.6' y1='1039.7' x2='1501.6' y2='1015.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1501.6' y1='1015.7' x2='1499.8' y2='1013.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1485.6" y="1022.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(52.9,1485.6,1022.8)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="G726G_rsID_rs752452705_1_67" sift="NA">p.G726G</text>
<line x1='1816.7' y1='667.5' x2='1815.3' y2='664.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1815.3' y1='664.8' x2='1801.7' y2='638.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1801.7' y1='638.1' x2='1800.4' y2='635.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1784.8" y="642.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(63.1,1784.8,642.2)" sift="NA" id="V749V_rsID_rs35803318_1_81" polyphen2="NA" class="mut" ipvMAF="0.02093" dbsource="dbSNP">p.V749V</text>
<line x1='4829.4' y1='1365.1' x2='4831.7' y2='1363.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4831.7' y1='1363.1' x2='4863.5' y2='1353.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4863.5' y1='1353.7' x2='4865.7' y2='1351.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4877.7" y="1363.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(318.5,4877.7,1363.9)" sift="NA" id="G104G_rsID_rs111420317_1_84" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.G104G</text>
<line x1='1079.0' y1='5019.9' x2='1076.9' y2='5022.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1076.9' y1='5022.1' x2='1081.4' y2='5067.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1081.4' y1='5067.4' x2='1079.4' y2='5069.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1091.2" y="5081.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-47.1,1091.2,5081.9)" dbsource="dbSNP" ipvMAF="0.000265" class="mut" polyphen2="0.323" id="A501T_rsID_rs140473595_1_87" sift="0.03">p.A501T</text>
<line x1='3370.9' y1='5601.2' x2='3371.3' y2='5604.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3371.3' y1='5604.2' x2='3375.5' y2='5633.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3375.5' y1='5633.9' x2='3375.9' y2='5636.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3359.2" y="5640.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(81.9,3359.2,5640.2)" sift="NA" id="A384A_rsID_rs138689466_1_88" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.A384A</text>
<line x1='5112.5' y1='1198.3' x2='5114.8' y2='1196.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5114.8' y1='1196.3' x2='5137.6' y2='1176.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5137.6' y1='1176.8' x2='5139.9' y2='1174.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5151.6" y="1187.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(319.5,5151.6,1187.2)" id="V107A_rsID_rs139773121_1_90" sift="1" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.005">p.V107A</text>
<line x1='4271.0' y1='5483.1' x2='4272.4' y2='5485.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4272.4' y1='5485.8' x2='4286.1' y2='5512.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4286.1' y1='5512.5' x2='4287.4' y2='5515.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4272.7" y="5523.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(62.9,4272.7,5523.7)" sift="0.02" id="K341R_rsID_rs138390800_1_95" polyphen2="0.215" class="mut" ipvMAF="0.000795" dbsource="dbSNP">p.K341R</text>
<line x1='2405.0' y1='276.7' x2='2404.4' y2='273.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2404.4' y1='273.8' x2='2398.0' y2='244.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2398.0' y1='244.5' x2='2397.4' y2='241.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2380.5" y="244.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(77.7,2380.5,244.3)" sift="0.27" id="A782V_rsID_rs147487891_1_103" polyphen2="0.001" class="mut" ipvMAF="NA" dbsource="dbSNP">p.A782V</text>
<line x1='268.5' y1='3514.2' x2='265.5' y2='3514.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='265.5' y1='3514.7' x2='236.0' y2='3520.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='236.0' y1='3520.3' x2='233.1' y2='3520.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="235.3" y="3537.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-10.7,235.3,3537.7)" sift="1" id="R582K_rsID_rs150172355_1_108" polyphen2="0.001" dbsource="dbSNP" ipvMAF="NA" class="mut">p.R582K</text>
<line x1='5438.0' y1='2724.3' x2='5440.9' y2='2724.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5440.9' y1='2724.0' x2='5470.8' y2='2720.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5470.8' y1='2720.6' x2='5473.7' y2='2720.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5476.6" y="2737.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(353.5,5476.6,2737.1)" id="V184G_rsID_rs758142853_1_113" sift="0" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.996">p.V184G</text>
<line x1='5602.9' y1='2705.7' x2='5605.9' y2='2705.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5605.9' y1='2705.4' x2='5635.7' y2='2702.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5635.7' y1='2702.0' x2='5638.7' y2='2701.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5641.5" y="2718.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(353.5,5641.5,2718.4)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.996" id="V184A_rsID_rs758142853_2_113" sift="0">p.V184A</text>
<line x1='2284.5' y1='481.1' x2='2283.7' y2='478.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2283.7' y1='478.3' x2='2275.5' y2='449.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2275.5' y1='449.4' x2='2274.7' y2='446.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2258.5" y="450.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(74.1,2258.5,450.1)" polyphen2="0.001" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.11" id="A774T_rsID_rs761408882_2_131">p.A774T</text>
<line x1='2239.1' y1='321.5' x2='2238.3' y2='318.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2238.3' y1='318.6' x2='2230.1' y2='289.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2230.1' y1='289.7' x2='2229.3' y2='286.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2213.2" y="290.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(74.1,2213.2,290.4)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="A774A_rsID_rs764422604_1_146">p.A774A</text>
<line x1='2239.7' y1='323.4' x2='2238.9' y2='320.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2238.9' y1='320.5' x2='2197.6' y2='301.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2197.6' y1='301.3' x2='2196.8' y2='298.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2180.7" y="302.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(73.4,2180.7,302.2)" id="A774A_rsID_rs764422604_2_146" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.A774A</text>
<line x1='936.4' y1='4327.1' x2='933.9' y2='4328.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='933.9' y1='4328.7' x2='908.6' y2='4345.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='908.6' y1='4345.0' x2='906.1' y2='4346.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="914.5" y="4361.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-32.7,914.5,4361.4)" id="A532T_rsID_rs763593286_1_150" sift="0.08" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.067">p.A532T</text>
<line x1='978.3' y1='4390.1' x2='975.8' y2='4391.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='975.8' y1='4391.8' x2='951.1' y2='4408.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='951.1' y1='4408.8' x2='948.6' y2='4410.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="957.5" y="4425.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-34.5,957.5,4425.0)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="A528A_rsID_rs766808999_1_158" sift="NA">p.A528A</text>
<line x1='4515.5' y1='4929.5' x2='4517.4' y2='4931.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4517.4' y1='4931.8' x2='4535.9' y2='4955.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4535.9' y1='4955.4' x2='4537.8' y2='4957.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4525.0" y="4969.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(51.9,4525.0,4969.0)" id="V316V_rsID_rs767374564_1_160" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.V316V</text>
<line x1='598.9' y1='2495.5' x2='596.0' y2='2494.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='596.0' y1='2494.9' x2='566.6' y2='2488.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='566.6' y1='2488.8' x2='563.7' y2='2488.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="559.3" y="2504.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(11.9,559.3,2504.6)" sift="NA" id="Y633Y_rsID_rs767537469_1_163" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.Y633Y</text>
<line x1='5376.4' y1='2389.8' x2='5379.3' y2='2389.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5379.3' y1='2389.0' x2='5408.4' y2='2381.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5408.4' y1='2381.6' x2='5411.3' y2='2380.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5416.4" y="2397.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(345.6,5416.4,2397.1)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.172" id="E166Q_rsID_rs769593006_1_166" sift="0.26">p.E166Q</text>
<line x1='789.6' y1='1305.0' x2='787.2' y2='1303.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='787.2' y1='1303.1' x2='763.4' y2='1284.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='763.4' y1='1284.9' x2='761.0' y2='1283.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="749.9" y="1296.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(37.5,749.9,1296.0)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="V691V_rsID_rs770114482_1_167">p.V691V</text>
<line x1='1053.1' y1='1507.0' x2='1050.7' y2='1505.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1050.7' y1='1505.2' x2='1048.0' y2='1459.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1048.0' y1='1459.7' x2='1045.7' y2='1457.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1034.4" y="1470.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(38.3,1034.4,1470.6)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="V691V_rsID_rs770114482_2_167" sift="NA">p.V691V</text>
<line x1='2042.7' y1='5608.4' x2='2041.7' y2='5611.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2041.7' y1='5611.2' x2='2031.3' y2='5639.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2031.3' y1='5639.4' x2='2030.3' y2='5642.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2045.9" y="5648.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-69.8,2045.9,5648.9)" sift="NA" id="G448G_rsID_rs770297403_1_172" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.G448G</text>
<line x1='384.8' y1='2962.4' x2='381.8' y2='2962.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='381.8' y1='2962.4' x2='351.8' y2='2962.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='351.8' y1='2962.0' x2='348.8' y2='2961.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="347.6" y="2978.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(0.8,347.6,2978.9)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.04" id="T608A_rsID_rs769786221_1_173" sift="0.2">p.T608A</text>
<line x1='4151.5' y1='5166.5' x2='4152.9' y2='5169.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4152.9' y1='5169.2' x2='4141.8' y2='5208.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4141.8' y1='5208.8' x2='4143.2' y2='5211.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4128.5" y="5220.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(62.7,4128.5,5220.1)" sift="1" id="V339G_rsID_rs772710779_1_188" polyphen2="0" class="mut" ipvMAF="NA" dbsource="dbSNP">p.V339G</text>
<line x1='916.2' y1='4295.1' x2='913.6' y2='4296.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='913.6' y1='4296.7' x2='888.2' y2='4312.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='888.2' y1='4312.5' x2='885.6' y2='4314.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="893.8" y="4329.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-31.9,893.8,4329.1)" id="K534R_rsID_rs773746588_1_190" sift="0.01" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.048">p.K534R</text>
<line x1='1241.9' y1='4711.4' x2='1239.8' y2='4713.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1239.8' y1='4713.5' x2='1198.6' y2='4713.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1198.6' y1='4713.9' x2='1196.4' y2='4716.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1207.4" y="4729.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-43.6,1207.4,4729.0)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.999" id="V506A_rsID_rs775181355_1_203" sift="0">p.V506A</text>
<line x1='584.5' y1='2569.8' x2='581.6' y2='2569.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='581.6' y1='2569.3' x2='552.0' y2='2564.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='552.0' y1='2564.0' x2='549.1' y2='2563.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="545.2" y="2580.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(10.1,545.2,2580.1)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.985" id="G629V_rsID_rs776696484_1_205" sift="0">p.G629V</text>
<line x1='5451.4' y1='3102.0' x2='5454.4' y2='3102.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5454.4' y1='3102.1' x2='5484.4' y2='3103.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5484.4' y1='3103.4' x2='5487.3' y2='3103.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5487.6" y="3120.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(2.4,5487.6,3120.5)" id="R204T_rsID_rs779790336_1_219" sift="0" ipvMAF="0.000265" dbsource="dbSNP" class="mut" polyphen2="0.999">p.R204T</text>
<line x1='5723.2' y1='2433.5' x2='5726.1' y2='2432.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5726.1' y1='2432.9' x2='5755.5' y2='2426.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5755.5' y1='2426.8' x2='5758.4' y2='2426.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5762.8" y="2442.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(348.2,5762.8,2442.6)" sift="NA" id="V172V_rsID_rs781175759_1_226" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.V172V</text>
<line x1='5320.0' y1='4188.1' x2='5322.7' y2='4189.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5322.7' y1='4189.4' x2='5349.4' y2='4203.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5349.4' y1='4203.1' x2='5352.0' y2='4204.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5345.1" y="4220.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(27.1,5345.1,4220.0)" id="G260X_rsID_rs868599322_1_234" sift="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA">p.G260X</text>
<line x1='764.8' y1='4011.7' x2='762.1' y2='4013.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='762.1' y1='4013.0' x2='734.7' y2='4025.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='734.7' y1='4025.3' x2='732.0' y2='4026.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="738.2" y="4042.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-24.4,738.2,4042.4)" id="G551X_rsID_rs867060899_1_236" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.G551X</text>
<line x1='5256.1' y1='3964.2' x2='5258.8' y2='3965.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5258.8' y1='3965.4' x2='5286.4' y2='3977.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5286.4' y1='3977.2' x2='5289.2' y2='3978.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5283.4" y="3994.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(23.1,5283.4,3994.4)" id="A251T_rsID_rs886466413_1_237" sift="0.44" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0">p.A251T</text>
<line x1='4101.1' y1='5192.6' x2='4102.4' y2='5195.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4102.4' y1='5195.2' x2='4103.2' y2='5228.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4103.2' y1='5228.4' x2='4104.5' y2='5231.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4089.7" y="5239.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(63.7,4089.7,5239.5)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="A342A_rsID_rs956290521_1_249" sift="NA">p.A342A</text>
<line x1='1377.8' y1='5056.8' x2='1376.0' y2='5059.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1376.0' y1='5059.1' x2='1357.4' y2='5082.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1357.4' y1='5082.7' x2='1355.5' y2='5085.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1368.3" y="5096.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-51.7,1368.3,5096.3)" id="E489Q_rsID_rs962791083_1_255" sift="0.02" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.992">p.E489Q</text>
<line x1='2049.1' y1='5261.7' x2='2047.9' y2='5264.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2047.9' y1='5264.5' x2='2036.3' y2='5292.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2036.3' y1='5292.2' x2='2035.1' y2='5294.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2050.0" y="5302.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-67.2,2050.0,5302.2)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="Y454X_rsID_rs1009196459_1_260" sift="NA">p.Y454X</text>
<line x1='579.9' y1='1629.0' x2='577.3' y2='1627.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='577.3' y1='1627.5' x2='551.2' y2='1612.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='551.2' y1='1612.7' x2='548.6' y2='1611.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="539.4" y="1625.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(29.5,539.4,1625.5)" sift="0.46" id="A673V_rsID_rs1027571965_1_265" polyphen2="0.045" dbsource="dbSNP" ipvMAF="NA" class="mut">p.A673V</text>
<line x1='865.3' y1='1790.6' x2='862.7' y2='1789.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='862.7' y1='1789.2' x2='853.8' y2='1744.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='853.8' y1='1744.5' x2='851.2' y2='1743.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="841.8" y="1757.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(30.3,841.8,1757.2)" id="A673G_rsID_rs1027571965_2_265" sift="0.46" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.045">p.A673G</text>
<line x1='5786.3' y1='3030.0' x2='5789.3' y2='3030.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5789.3' y1='3030.0' x2='5819.3' y2='3030.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5819.3' y1='3030.3' x2='5822.3' y2='3030.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5823.1" y="3047.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(0.6,5823.1,3047.4)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="G200G_rsID_rs1039062494_1_269" sift="NA">p.G200G</text>
<line x1='5453.4' y1='3026.4' x2='5456.4' y2='3026.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5456.4' y1='3026.4' x2='5485.7' y2='3061.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5485.7' y1='3061.2' x2='5488.7' y2='3061.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5489.3" y="3078.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(1.4,5489.3,3078.3)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="G200G_rsID_rs1039062494_2_269">p.G200G</text>
<line x1='961.4' y1='4646.6' x2='959.1' y2='4648.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='959.1' y1='4648.5' x2='935.8' y2='4667.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='935.8' y1='4667.3' x2='933.4' y2='4669.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="943.4" y="4683.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-38.9,943.4,4683.0)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="1" id="R518T_rsID_rs1158307424_1_273" sift="0.02">p.R518T</text>
<line x1='657.3' y1='3729.0' x2='654.5' y2='3729.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='654.5' y1='3729.9' x2='625.8' y2='3738.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='625.8' y1='3738.8' x2='622.9' y2='3739.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="627.1" y="3756.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-17.3,627.1,3756.2)" polyphen2="0.915" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.2" id="T567A_rsID_rs1212751713_1_302">p.T567A</text>
<line x1='4470.5' y1='4964.0' x2='4472.3' y2='4966.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4472.3' y1='4966.4' x2='4490.3' y2='4990.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4490.3' y1='4990.4' x2='4492.1' y2='4992.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4479.0" y="5003.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(53.2,4479.0,5003.7)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="G319G_rsID_rs1221192598_1_306">p.G319G</text>
<line x1='5787.7' y1='2836.4' x2='5790.7' y2='2836.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5790.7' y1='2836.2' x2='5820.6' y2='2834.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5820.6' y1='2834.4' x2='5823.6' y2='2834.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5825.6" y="2851.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(356.6,5825.6,2851.2)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="A191A_rsID_rs1234885259_1_310">p.A191A</text>
<line x1='837.9' y1='1840.3' x2='835.2' y2='1838.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='835.2' y1='1838.9' x2='808.8' y2='1824.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='808.8' y1='1824.7' x2='806.1' y2='1823.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="797.3" y="1837.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(28.2,797.3,1837.8)" id="V670A_rsID_rs1250368104_1_320" sift="0" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.529">p.V670A</text>
<line x1='637.1' y1='1538.3' x2='634.5' y2='1536.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='634.5' y1='1536.7' x2='609.0' y2='1520.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='609.0' y1='1520.9' x2='606.4' y2='1519.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="596.7" y="1533.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(31.7,596.7,1533.3)" sift="0" id="R678T_rsID_rs1271264671_1_332" polyphen2="0.999" class="mut" ipvMAF="NA" dbsource="dbSNP">p.R678T</text>
<line x1='2420.7' y1='443.3' x2='2420.1' y2='440.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2420.1' y1='440.4' x2='2413.4' y2='411.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2413.4' y1='411.1' x2='2412.8' y2='408.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2396.0" y="411.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(77.2,2396.0,411.0)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="Y781Y_rsID_rs1277737097_1_334">p.Y781Y</text>
<line x1='5535.5' y1='2307.1' x2='5538.4' y2='2306.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5538.4' y1='2306.3' x2='5567.4' y2='2298.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5567.4' y1='2298.4' x2='5570.3' y2='2297.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5575.6" y="2313.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(344.7,5575.6,2313.7)" id="A164G_rsID_rs1303797112_1_342" sift="0" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.834">p.A164G</text>
<line x1='3569.2' y1='5386.6' x2='3569.9' y2='5389.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3569.9' y1='5389.5' x2='3576.9' y2='5418.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3576.9' y1='5418.7' x2='3577.5' y2='5421.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3561.2" y="5426.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(76.6,3561.2,5426.4)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA" id="A372A_rsID_rs1304733999_1_343" sift="NA">p.A372A</text>
<line x1='462.6' y1='3662.6' x2='459.7' y2='3663.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='459.7' y1='3663.4' x2='430.7' y2='3671.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='430.7' y1='3671.0' x2='427.8' y2='3671.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="431.1" y="3688.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-14.6,431.1,3688.4)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.174" id="V573A_rsID_rs1303528080_1_344" sift="0.08">p.V573A</text>
<line x1='2239.1' y1='321.5' x2='2238.3' y2='318.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2238.3' y1='318.6' x2='2265.6' y2='279.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2265.6' y1='279.9' x2='2264.8' y2='277.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2248.1" y="280.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(74.9,2248.1,280.5)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.001" id="A774G_rsID_rs1307986087_1_347" sift="0.17">p.A774G</text>
<line x1='2275.2' y1='656.0' x2='2274.3' y2='653.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2274.3' y1='653.1' x2='2265.4' y2='624.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2265.4' y1='624.5' x2='2264.6' y2='621.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2248.0" y="625.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(72.8,2248.0,625.7)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.001" id="K771R_rsID_rs1323382709_1_355" sift="0.47">p.K771R</text>
<line x1='698.3' y1='2150.5' x2='695.4' y2='2149.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='695.4' y1='2149.5' x2='667.3' y2='2139.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='667.3' y1='2139.1' x2='664.5' y2='2138.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="657.7" y="2153.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(20.3,657.7,2153.7)" sift="0.01" id="R652K_rsID_rs1334127098_1_357" polyphen2="0.718" class="mut" ipvMAF="NA" dbsource="dbSNP">p.R652K</text>
<line x1='5317.5' y1='3805.5' x2='5320.3' y2='3806.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5320.3' y1='3806.5' x2='5348.7' y2='3816.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5348.7' y1='3816.4' x2='5351.5' y2='3817.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5346.8" y="3833.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(19.2,5346.8,3833.7)" sift="0" id="A242V_rsID_rs1360329820_1_374" polyphen2="0.615" class="mut" dbsource="dbSNP" ipvMAF="NA">p.A242V</text>
<line x1='4883.9' y1='4812.9' x2='4886.0' y2='4815.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4886.0' y1='4815.0' x2='4897.1' y2='4846.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4897.1' y1='4846.7' x2='4899.3' y2='4848.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4888.1" y="4861.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(44.2,4888.1,4861.6)" sift="0.05" id="V298A_rsID_rs1362308420_1_375" polyphen2="0.051" class="mut" ipvMAF="NA" dbsource="dbSNP">p.V298A</text>
<line x1='5089.1' y1='1713.4' x2='5091.7' y2='1711.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5091.7' y1='1711.8' x2='5117.2' y2='1696.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5117.2' y1='1696.1' x2='5119.8' y2='1694.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5129.5" y="1708.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(328.4,5129.5,1708.5)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="Y127Y_rsID_rs1398027862_1_392">p.Y127Y</text>
<line x1='5789.9' y1='2944.0' x2='5792.9' y2='2943.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5792.9' y1='2943.9' x2='5822.9' y2='2943.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5822.9' y1='2943.3' x2='5825.9' y2='2943.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5827.2" y="2960.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(358.8,5827.2,2960.2)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA" id="Y196Y_rsID_rs1416468883_1_401" sift="NA">p.Y196Y</text>
<line x1='599.1' y1='1985.4' x2='596.3' y2='1984.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='596.3' y1='1984.3' x2='568.7' y2='1972.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='568.7' y1='1972.6' x2='565.9' y2='1971.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="558.4" y="1986.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(22.9,558.4,1986.7)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA" id="V658V_rsID_rs1418717992_1_403" sift="NA">p.V658V</text>
<line x1='573.1' y1='3360.6' x2='570.2' y2='3361.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='570.2' y1='3361.1' x2='538.5' y2='3351.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='538.5' y1='3351.4' x2='535.5' y2='3351.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="537.0" y="3368.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-8.1,537.0,3368.8)" id="Y587Y_rsID_rs1423623219_1_406" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.Y587Y</text>
<line x1='2831.8' y1='552.3' x2='2831.6' y2='549.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2831.6' y1='549.3' x2='2829.5' y2='519.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2829.5' y1='519.4' x2='2829.3' y2='516.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2812.3" y="516.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(86.1,2812.3,516.6)" id="V801V_rsID_rs1423362553_1_408" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.V801V</text>
<line x1='1008.0' y1='1567.7' x2='1005.5' y2='1566.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1005.5' y1='1566.0' x2='981.2' y2='1548.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='981.2' y1='1548.5' x2='978.7' y2='1546.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="968.0" y="1560.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(35.7,968.0,1560.0)" id="A687A_rsID_rs1430341453_1_409" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.A687A</text>
<line x1='2680.3' y1='405.1' x2='2679.9' y2='402.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2679.9' y1='402.1' x2='2676.3' y2='372.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2676.3' y1='372.4' x2='2675.9' y2='369.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2658.9" y="370.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(83.0,2658.9,370.5)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="G794X_rsID_rs1437492704_1_413" sift="NA">p.G794X</text>
<line x1='714.4' y1='1728.4' x2='711.8' y2='1726.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='711.8' y1='1726.9' x2='693.0' y2='1699.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='693.0' y1='1699.1' x2='690.4' y2='1697.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="681.2" y="1712.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(29.4,681.2,1712.0)" sift="0.07" id="V672A_rsID_rs1449878623_1_423" polyphen2="0.045" ipvMAF="NA" dbsource="dbSNP" class="mut">p.V672A</text>
<line x1='2820.4' y1='386.7' x2='2820.2' y2='383.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2820.2' y1='383.7' x2='2818.1' y2='353.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2818.1' y1='353.7' x2='2817.9' y2='350.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2800.9" y="351.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(86.1,2800.9,351.0)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.003" id="V801G_rsID_rs1464340051_1_432" sift="0.3">p.V801G</text>
<line x1='1525.6' y1='4961.1' x2='1523.8' y2='4963.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1523.8' y1='4963.5' x2='1505.8' y2='4987.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1505.8' y1='4987.4' x2='1503.9' y2='4989.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1517.0" y="5000.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-53.1,1517.0,5000.8)" id="G486G_rsID_rs1480725606_1_440" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.G486G</text>
<line x1='430.6' y1='3483.7' x2='427.7' y2='3484.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='427.7' y1='3484.2' x2='398.2' y2='3489.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='398.2' y1='3489.8' x2='395.2' y2='3490.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="397.5" y="3507.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-10.7,397.5,3507.2)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.024" id="R582R_rsID_rs372924787_2_26" sift="0.69">p.R582R</text>
<line x1='5453.5' y1='3007.5' x2='5456.5' y2='3007.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5456.5' y1='3007.5' x2='5486.4' y2='3021.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5486.4' y1='3021.8' x2='5489.4' y2='3021.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5490.2" y="3038.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(0.5,5490.2,3038.8)" sift="0.04" id="Y199C_rsID_rs750145841_1_56" polyphen2="0.99" dbsource="dbSNP" ipvMAF="NA" class="mut">p.Y199C</text>
<line x1='868.0' y1='1202.6' x2='865.8' y2='1200.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='865.8' y1='1200.7' x2='842.8' y2='1181.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='842.8' y1='1181.4' x2='840.5' y2='1179.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="828.8" y="1191.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(40.1,828.8,1191.8)" sift="0" id="R697G_rsID_rs751603885_1_63" polyphen2="0.357" class="mut" ipvMAF="NA" dbsource="dbSNP">p.R697G</text>
<line x1='5616.0' y1='3169.5' x2='5619.0' y2='3169.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5619.0' y1='3169.7' x2='5648.9' y2='3171.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5648.9' y1='3171.7' x2='5651.9' y2='3171.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5651.8" y="3188.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(3.7,5651.8,3188.9)" id="Y207C_rsID_rs754237613_1_70" sift="0" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="1">p.Y207C</text>
<line x1='5431.5' y1='3328.0' x2='5434.4' y2='3328.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5434.4' y1='3328.4' x2='5464.2' y2='3332.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5464.2' y1='3332.4' x2='5467.2' y2='3332.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5465.8" y="3349.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(7.7,5465.8,3349.8)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0" id="D216E_rsID_rs753164828_1_74" sift="0.84">p.D216E</text>
<line x1='981.2' y1='1324.5' x2='978.9' y2='1322.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='978.9' y1='1322.6' x2='955.8' y2='1303.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='955.8' y1='1303.4' x2='953.5' y2='1301.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="941.9" y="1314.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(39.7,941.9,1314.0)" polyphen2="0.874" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="P696T_rsID_rs755445931_1_75">p.P696T</text>
<line x1='1421.4' y1='909.6' x2='1419.6' y2='907.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1419.6' y1='907.2' x2='1401.5' y2='883.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1401.5' y1='883.2' x2='1399.7' y2='880.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1385.6" y="890.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(52.9,1385.6,890.3)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="1" id="G726R_rsID_rs139980377_1_91" sift="0">p.G726R</text>
<line x1='552.6' y1='3172.7' x2='549.6' y2='3172.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='549.6' y1='3172.9' x2='519.7' y2='3175.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='519.7' y1='3175.0' x2='516.7' y2='3175.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="516.9" y="3192.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-4.0,516.9,3192.2)" id="D597E_rsID_rs145437639_1_99" sift="1" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0">p.D597E</text>
<line x1='5442.3' y1='3234.1' x2='5445.3' y2='3234.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5445.3' y1='3234.4' x2='5475.2' y2='3237.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5475.2' y1='3237.2' x2='5478.1' y2='3237.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5477.5" y="3254.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(5.5,5477.5,3254.5)" sift="0.35" id="G211R_rsID_rs148771870_1_106" polyphen2="0.449" ipvMAF="NA" dbsource="dbSNP" class="mut">p.G211R</text>
<line x1='2329.6' y1='639.9' x2='2328.8' y2='637.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2328.8' y1='637.0' x2='2320.6' y2='608.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2320.6' y1='608.1' x2='2319.8' y2='605.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2303.6" y="608.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(74.1,2303.6,608.8)" polyphen2="0.001" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.11" id="A774P_rsID_rs761408882_1_131">p.A774P</text>
<line x1='2582.8' y1='5735.9' x2='2582.4' y2='5738.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2582.4' y1='5738.8' x2='2577.9' y2='5768.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2577.9' y1='5768.5' x2='2577.4' y2='5771.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2594.1" y="5775.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-81.3,2594.1,5775.0)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.995" id="G422C_rsID_rs761489852_1_132" sift="0">p.G422C</text>
<line x1='4268.8' y1='5300.9' x2='4270.2' y2='5303.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4270.2' y1='5303.5' x2='4284.7' y2='5329.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4284.7' y1='5329.8' x2='4286.1' y2='5332.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4271.7" y="5341.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(61.1,4271.7,5341.4)" sift="0.2" id="G337R_rsID_rs762357444_1_139" polyphen2="0.319" class="mut" dbsource="dbSNP" ipvMAF="NA">p.G337R</text>
<line x1='5623.0' y1='2846.0' x2='5626.0' y2='2845.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5626.0' y1='2845.9' x2='5655.9' y2='2844.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5655.9' y1='2844.1' x2='5658.9' y2='2843.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5660.9" y="2860.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(356.6,5660.9,2860.8)" polyphen2="0.991" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0" id="A191P_rsID_rs765733397_1_154">p.A191P</text>
<line x1='5190.6' y1='1895.0' x2='5193.2' y2='1893.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5193.2' y1='1893.6' x2='5220.0' y2='1880.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5220.0' y1='1880.1' x2='5222.7' y2='1878.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5231.2" y="1893.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(333.2,5231.2,1893.5)" polyphen2="0.009" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.04" id="P138A_rsID_rs766124365_1_155">p.P138A</text>
<line x1='5554.7' y1='4115.2' x2='5557.4' y2='4116.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5557.4' y1='4116.4' x2='5584.9' y2='4128.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5584.9' y1='4128.4' x2='5587.7' y2='4129.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5581.7" y="4145.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(23.6,5581.7,4145.6)" id="Y252C_rsID_rs771769548_1_180" sift="0" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.998">p.Y252C</text>
<line x1='1571.3' y1='4994.6' x2='1569.6' y2='4997.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1569.6' y1='4997.1' x2='1540.6' y2='5013.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1540.6' y1='5013.2' x2='1538.8' y2='5015.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1552.0" y="5026.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-54.1,1552.0,5026.3)" polyphen2="0.003" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.18" id="E483D_rsID_rs779752560_1_218">p.E483D</text>
<line x1='1870.3' y1='5373.4' x2='1869.0' y2='5376.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1869.0' y1='5376.1' x2='1856.1' y2='5403.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1856.1' y1='5403.2' x2='1854.8' y2='5405.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1869.8" y="5414.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-64.5,1869.8,5414.0)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="R460R_rsID_rs981162998_1_257">p.R460R</text>
<line x1='5389.9' y1='2444.9' x2='5392.8' y2='2444.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5392.8' y1='2444.2' x2='5422.0' y2='2437.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5422.0' y1='2437.4' x2='5424.9' y2='2436.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5429.7" y="2453.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(346.9,5429.7,2453.1)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="R169R_rsID_rs1165363168_1_277">p.R169R</text>
<line x1='2555.6' y1='5412.9' x2='2555.0' y2='5415.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2555.0' y1='5415.9' x2='2549.6' y2='5445.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2549.6' y1='5445.4' x2='2549.0' y2='5448.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2565.6" y="5452.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-79.6,2565.6,5452.3)" sift="0.2" id="P426A_rsID_rs1238146879_1_312" polyphen2="0.003" class="mut" ipvMAF="NA" dbsource="dbSNP">p.P426A</text>
<line x1='436.5' y1='2461.4' x2='433.5' y2='2460.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='433.5' y1='2460.8' x2='404.2' y2='2454.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='404.2' y1='2454.6' x2='401.2' y2='2454.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="396.8" y="2470.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(11.9,396.8,2470.5)" id="Y633C_rsID_rs1238269881_1_313" sift="0" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.999">p.Y633C</text>
<line x1='873.4' y1='4800.6' x2='871.1' y2='4802.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='871.1' y1='4802.5' x2='837.8' y2='4809.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='837.8' y1='4809.6' x2='835.5' y2='4811.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="845.7" y="4825.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-39.9,845.7,4825.1)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="1" id="Y515C_rsID_rs1263424292_1_328" sift="0">p.Y515C</text>
<line x1='5758.5' y1='3393.8' x2='5761.5' y2='3394.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5761.5' y1='3394.2' x2='5791.2' y2='3398.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5791.2' y1='3398.5' x2='5794.2' y2='3398.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5792.7" y="3415.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(8.1,5792.7,3415.9)" id="Y217C_rsID_rs1300152093_1_341" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.998">p.Y217C</text>
<line x1='634.6' y1='2348.5' x2='631.7' y2='2347.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='631.7' y1='2347.7' x2='602.8' y2='2339.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='602.8' y1='2339.8' x2='599.9' y2='2339.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="594.4" y="2355.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(15.4,594.4,2355.1)" sift="0" id="Y641C_rsID_rs1339201462_1_360" polyphen2="0.966" dbsource="dbSNP" ipvMAF="NA" class="mut">p.Y641C</text>
<line x1='3093.9' y1='5785.9' x2='3094.0' y2='5788.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3094.0' y1='5788.9' x2='3095.0' y2='5818.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3095.0' y1='5818.9' x2='3095.1' y2='5821.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3078.2" y="5823.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(88.1,3078.2,5823.4)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.406" id="E398D_rsID_rs1339365248_1_361" sift="0.29">p.E398D</text>
<line x1='5557.5' y1='2447.4' x2='5560.4' y2='2446.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5560.4' y1='2446.8' x2='5589.7' y2='2440.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5589.7' y1='2440.4' x2='5592.7' y2='2439.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5597.2" y="2456.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(347.8,5597.2,2456.2)" sift="0.53" id="E171D_rsID_rs1341206593_1_363" polyphen2="0" class="mut" ipvMAF="NA" dbsource="dbSNP">p.E171D</text>
<line x1='1418.0' y1='1124.6' x2='1416.1' y2='1122.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1416.1' y1='1122.4' x2='1396.7' y2='1099.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1396.7' y1='1099.4' x2='1394.8' y2='1097.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1381.2" y="1107.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(49.8,1381.2,1107.4)" polyphen2="0.999" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="D719E_rsID_rs1350774050_1_370">p.D719E</text>
<line x1='1012.4' y1='4709.3' x2='1010.1' y2='4711.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1010.1' y1='4711.3' x2='987.4' y2='4730.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='987.4' y1='4730.8' x2='985.1' y2='4732.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="995.5" y="4746.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-40.7,995.5,4746.3)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="R514X_rsID_rs1352194082_1_372">p.R514X</text>
<line x1='887.3' y1='4816.9' x2='885.0' y2='4818.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='885.0' y1='4818.9' x2='862.3' y2='4838.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='862.3' y1='4838.4' x2='860.0' y2='4840.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="870.4" y="4853.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-40.7,870.4,4853.9)" sift="NA" id="R514G_rsID_rs1352194082_2_372" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.R514G</text>
<line x1='5242.3' y1='4352.2' x2='5244.9' y2='4353.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5244.9' y1='4353.8' x2='5270.6' y2='4369.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5270.6' y1='4369.3' x2='5273.1' y2='4370.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5265.2" y="4385.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(31.1,5265.2,4385.9)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.997" id="D269E_rsID_rs1365337188_1_377" sift="0">p.D269E</text>
<line x1='616.8' y1='3583.3' x2='613.9' y2='3584.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='613.9' y1='3584.0' x2='581.4' y2='3577.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='581.4' y1='3577.3' x2='578.5' y2='3578.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="581.6" y="3594.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-13.4,581.6,3594.8)" id="G575R_rsID_rs1367658189_1_379" sift="0.01" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.98">p.G575R</text>
<line x1='5363.6' y1='1875.5' x2='5366.3' y2='1874.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5366.3' y1='1874.2' x2='5393.4' y2='1861.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5393.4' y1='1861.3' x2='5396.1' y2='1860.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5404.3" y="1874.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(334.6,5404.3,1874.9)" sift="0" id="C141Y_rsID_rs1391451327_1_386" polyphen2="0.998" dbsource="dbSNP" ipvMAF="NA" class="mut">p.C141Y</text>
<line x1='3584.2' y1='5727.6' x2='3584.9' y2='5730.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3584.9' y1='5730.6' x2='3591.1' y2='5759.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3591.1' y1='5759.9' x2='3591.8' y2='5762.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3575.3" y="5767.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(77.9,3575.3,5767.3)" sift="0" id="E375D_rsID_rs1395782023_1_389" polyphen2="1" ipvMAF="NA" dbsource="dbSNP" class="mut">p.E375D</text>
<line x1='5750.2' y1='3436.0' x2='5753.1' y2='3436.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5753.1' y1='3436.4' x2='5782.8' y2='3441.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5782.8' y1='3441.1' x2='5785.7' y2='3441.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5784.0" y="3458.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(9.0,5784.0,3458.5)" sift="NA" id="R219R_rsID_rs1399442625_1_393" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.R219R</text>
<line x1='5110.7' y1='4250.8' x2='5113.3' y2='4252.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5113.3' y1='4252.3' x2='5139.1' y2='4267.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5139.1' y1='4267.6' x2='5141.7' y2='4269.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5133.8" y="4284.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(30.7,5133.8,4284.2)" id="G268C_rsID_rs1407010163_1_396" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="1">p.G268C</text>
<line x1='1606.8' y1='787.6' x2='1605.2' y2='785.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1605.2' y1='785.1' x2='1589.2' y2='759.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1589.2' y1='759.7' x2='1587.6' y2='757.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1572.7" y="765.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(57.8,1572.7,765.4)" sift="0.14" id="P737A_rsID_rs1416534293_2_402" polyphen2="0.035" dbsource="dbSNP" ipvMAF="NA" class="mut">p.P737A</text>
<line x1='650.3' y1='2294.0' x2='647.4' y2='2293.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='647.4' y1='2293.1' x2='618.7' y2='2284.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='618.7' y1='2284.5' x2='615.8' y2='2283.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="610.0" y="2299.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(16.7,610.0,2299.6)" sift="NA" id="R644R_rsID_rs1431656720_1_410" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.R644R</text>
<line x1='675.4' y1='1799.0' x2='672.8' y2='1797.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='672.8' y1='1797.6' x2='646.1' y2='1783.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='646.1' y1='1783.8' x2='643.5' y2='1782.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="634.8" y="1797.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(27.3,634.8,1797.1)" sift="0.11" id="E668K_rsID_rs200180615_1_6" polyphen2="0.005" ipvMAF="0.00053" dbsource="dbSNP" class="mut">p.E668K</text>
<line x1='4961.3' y1='1525.9' x2='4963.7' y2='1524.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4963.7' y1='1524.1' x2='4987.7' y2='1506.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4987.7' y1='1506.1' x2='4990.1' y2='1504.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5001.1" y="1517.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(323.1,5001.1,1517.3)" polyphen2="0.743" dbsource="dbSNP" ipvMAF="0.000265" class="mut" sift="0.01" id="R115P_rsID_rs201900069_1_16">p.R115P</text>
<line x1='5423.2' y1='3384.1' x2='5426.2' y2='3384.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5426.2' y1='3384.6' x2='5455.8' y2='3389.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5455.8' y1='3389.3' x2='5458.8' y2='3389.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5457.1" y="3406.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(9.0,5457.1,3406.7)" polyphen2="0.976" class="mut" ipvMAF="0.000265" dbsource="dbSNP" sift="0" id="R219C_rsID_rs372272603_1_33">p.R219C</text>
<line x1='3271.3' y1='5438.5' x2='3271.6' y2='5441.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3271.6' y1='5441.4' x2='3274.9' y2='5471.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3274.9' y1='5471.3' x2='3275.2' y2='5474.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3258.4" y="5477.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(83.7,3258.4,5477.1)" polyphen2="0.111" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.7" id="Q388L_rsID_rs751572714_1_62">p.Q388L</text>
<line x1='701.2' y1='1744.1' x2='698.6' y2='1742.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='698.6' y1='1742.7' x2='672.2' y2='1728.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='672.2' y1='1728.3' x2='669.6' y2='1726.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="660.6" y="1741.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(28.6,660.6,1741.3)" sift="0.2" id="R671P_rsID_rs753705431_1_71" polyphen2="0.334" class="mut" dbsource="dbSNP" ipvMAF="NA">p.R671P</text>
<line x1='1159.2' y1='917.5' x2='1157.2' y2='915.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1157.2' y1='915.2' x2='1137.3' y2='892.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1137.3' y1='892.8' x2='1135.3' y2='890.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1121.9" y="901.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(48.5,1121.9,901.1)" sift="0.01" id="R716C_rsID_rs144869363_1_98" polyphen2="0.513" class="mut" ipvMAF="NA" dbsource="dbSNP">p.R716C</text>
<line x1='2761.5' y1='5441.9' x2='2761.2' y2='5444.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2761.2' y1='5444.9' x2='2758.3' y2='5474.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2758.3' y1='5474.7' x2='2758.0' y2='5477.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2774.8" y="5480.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-84.4,2774.8,5480.3)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="P415P_rsID_rs769251490_1_170" sift="NA">p.P415P</text>
<line x1='2132.2' y1='339.5' x2='2131.2' y2='336.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2131.2' y1='336.6' x2='2121.9' y2='308.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2121.9' y1='308.1' x2='2121.0' y2='305.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2104.5" y="309.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(71.9,2104.5,309.6)" id="K769E_rsID_rs772347875_1_182" sift="0" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.26">p.K769E</text>
<line x1='4881.5' y1='4574.6' x2='4883.8' y2='4576.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4883.8' y1='4576.6' x2='4906.8' y2='4595.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4906.8' y1='4595.8' x2='4909.1' y2='4597.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4899.0" y="4611.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(39.9,4899.0,4611.4)" id="P289P_rsID_rs773273611_1_184" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.P289P</text>
<line x1='3088.4' y1='5622.0' x2='3088.5' y2='5625.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3088.5' y1='5625.0' x2='3089.5' y2='5655.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3089.5' y1='5655.0' x2='3089.6' y2='5658.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3072.6" y="5659.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(88.1,3072.6,5659.5)" polyphen2="0.994" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0.1" id="E398K_rsID_rs772619843_1_186">p.E398K</text>
<line x1='766.0' y1='1641.7' x2='763.4' y2='1640.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='763.4' y1='1640.2' x2='737.8' y2='1624.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='737.8' y1='1624.6' x2='735.2' y2='1623.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="725.6" y="1637.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(31.3,725.6,1637.1)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="P677P_rsID_rs775548770_1_202" sift="NA">p.P677P</text>
<line x1='765.3' y1='1340.4' x2='762.9' y2='1338.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='762.9' y1='1338.6' x2='738.8' y2='1320.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='738.8' y1='1320.8' x2='736.4' y2='1319.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="725.5" y="1332.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(36.6,725.5,1332.1)" polyphen2="0" class="mut" ipvMAF="0.000265" dbsource="dbSNP" sift="0.53" id="K689E_rsID_rs777410473_1_216">p.K689E</text>
<line x1='4574.3' y1='4881.8' x2='4576.2' y2='4884.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4576.2' y1='4884.1' x2='4584.6' y2='4916.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4584.6' y1='4916.2' x2='4586.5' y2='4918.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4574.0" y="4930.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(50.4,4574.0,4930.1)" ipvMAF="0.000265" dbsource="dbSNP" class="mut" polyphen2="0.581" id="E312K_rsID_rs780574871_1_224" sift="0">p.E312K</text>
<line x1='1175.5' y1='1119.0' x2='1173.4' y2='1116.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1173.4' y1='1116.8' x2='1163.5' y2='1084.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1163.5' y1='1084.8' x2='1161.4' y2='1082.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1148.5" y="1093.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(46.2,1148.5,1093.7)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="1" id="R710C_rsID_rs901495523_1_240" sift="0">p.R710C</text>
<line x1='5215.5' y1='1945.9' x2='5218.2' y2='1944.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5218.2' y1='1944.6' x2='5245.3' y2='1931.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5245.3' y1='1931.8' x2='5248.0' y2='1930.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5256.2" y="1945.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(334.6,5256.2,1945.4)" id="C141C_rsID_rs1157386586_1_272" sift="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA">p.C141C</text>
<line x1='5357.6' y1='3679.4' x2='5360.5' y2='3680.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5360.5' y1='3680.2' x2='5389.3' y2='3688.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5389.3' y1='3688.5' x2='5392.2' y2='3689.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5388.4" y="3705.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(16.1,5388.4,3705.9)" polyphen2="0.99" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="P235R_rsID_rs1172580854_1_280">p.P235R</text>
<line x1='1206.7' y1='4914.9' x2='1204.7' y2='4917.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1204.7' y1='4917.1' x2='1184.2' y2='4939.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1184.2' y1='4939.0' x2='1182.1' y2='4941.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1193.9" y="4953.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-46.9,1193.9,4953.5)" sift="NA" id="P500P_rsID_rs1205522386_1_299" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.P500P</text>
<line x1='1663.2' y1='5457.4' x2='1661.8' y2='5460.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1661.8' y1='5460.1' x2='1647.4' y2='5486.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1647.4' y1='5486.4' x2='1646.0' y2='5489.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1660.5" y="5498.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-61.5,1660.5,5498.0)" sift="0.26" id="E467K_rsID_rs1270795706_1_330" polyphen2="0.019" dbsource="dbSNP" ipvMAF="NA" class="mut">p.E467K</text>
<line x1='885.0' y1='1454.5' x2='882.6' y2='1452.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='882.6' y1='1452.7' x2='858.4' y2='1435.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='858.4' y1='1435.0' x2='856.0' y2='1433.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="845.2" y="1446.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(36.2,845.2,1446.4)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.078" id="P688R_rsID_rs1284743203_1_336" sift="0.02">p.P688R</text>
<line x1='2525.7' y1='5575.2' x2='2525.1' y2='5578.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2525.1' y1='5578.1' x2='2519.7' y2='5607.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2519.7' y1='5607.6' x2='2519.1' y2='5610.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2535.7" y="5614.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-79.6,2535.7,5614.6)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="P426P_rsID_rs1335386721_1_358">p.P426P</text>
<line x1='5196.3' y1='4698.6' x2='5198.7' y2='4700.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5198.7' y1='4700.4' x2='5222.4' y2='4718.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5222.4' y1='4718.8' x2='5224.8' y2='4720.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5215.1" y="4734.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(37.7,5215.1,4734.6)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="P284P_rsID_rs1344315438_1_365">p.P284P</text>
<line x1='5337.9' y1='1820.7' x2='5340.6' y2='1819.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5340.6' y1='1819.3' x2='5367.3' y2='1805.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5367.3' y1='1805.8' x2='5370.0' y2='1804.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5378.5" y="1819.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(333.2,5378.5,1819.2)" sift="NA" id="P138P_rsID_rs1457896076_1_426" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.P138P</text>
<line x1='620.1' y1='2403.4' x2='617.2' y2='2402.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='617.2' y1='2402.7' x2='588.1' y2='2395.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='588.1' y1='2395.4' x2='585.2' y2='2394.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="580.2" y="2410.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(14.1,580.2,2410.9)" id="N638S_rsID_rs183135788_1_0" sift="0.33" dbsource="dbSNP" ipvMAF="0.00053" class="mut" polyphen2="0.054">p.N638S</text>
<line x1='5276.3' y1='2084.5' x2='5279.1' y2='2083.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5279.1' y1='2083.4' x2='5306.9' y2='2072.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5306.9' y1='2072.2' x2='5309.7' y2='2071.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5316.9" y="2086.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(338.1,5316.9,2086.5)" id="N149S_rsID_rs373252182_1_30" sift="0.19" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.015">p.N149S</text>
<line x1='5335.1' y1='4128.4' x2='5337.8' y2='4129.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5337.8' y1='4129.7' x2='5364.8' y2='4142.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5364.8' y1='4142.8' x2='5367.5' y2='4144.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5361.0" y="4159.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(25.8,5361.0,4159.8)" id="S257N_rsID_rs745514718_1_40" sift="0.93" class="mut" ipvMAF="0.000265" dbsource="dbSNP" polyphen2="0.006">p.S257N</text>
<line x1='5500.3' y1='2212.0' x2='5503.1' y2='2211.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5503.1' y1='2211.1' x2='5531.7' y2='2202.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5531.7' y1='2202.1' x2='5534.6' y2='2201.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5540.6" y="2217.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(342.5,5540.6,2217.1)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0" id="N159S_rsID_rs746034076_1_41" sift="0.79">p.N159S</text>
<line x1='1327.1' y1='985.6' x2='1325.2' y2='983.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1325.2' y1='983.3' x2='1306.0' y2='960.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1306.0' y1='960.2' x2='1304.1' y2='957.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1290.4" y="968.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(50.3,1290.4,968.0)" sift="0.11" id="N720S_rsID_rs746153383_1_42" polyphen2="0.014" ipvMAF="NA" dbsource="dbSNP" class="mut">p.N720S</text>
<line x1='5398.2' y1='2481.8' x2='5401.1' y2='2481.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5401.1' y1='2481.2' x2='5430.4' y2='2474.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5430.4' y1='2474.8' x2='5433.3' y2='2474.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5437.9" y="2490.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(347.8,5437.9,2490.6)" id="E171V_rsID_rs748076875_1_49" sift="0.26" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.003">p.E171V</text>
<line x1='4314.9' y1='5071.4' x2='4316.5' y2='5073.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4316.5' y1='5073.9' x2='4332.6' y2='5099.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4332.6' y1='5099.3' x2='4334.2' y2='5101.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4320.3" y="5111.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(57.6,4320.3,5111.7)" polyphen2="0.02" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.13" id="E329G_rsID_rs143936283_1_100">p.E329G</text>
<line x1='805.5' y1='4097.1' x2='802.8' y2='4098.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='802.8' y1='4098.4' x2='775.9' y2='4111.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='775.9' y1='4111.9' x2='773.3' y2='4113.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="780.0" y="4128.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-26.6,780.0,4128.8)" sift="0.04" id="N546S_rsID_rs756905974_1_109" polyphen2="0.029" ipvMAF="0.000265" dbsource="dbSNP" class="mut">p.N546S</text>
<line x1='1322.0' y1='777.9' x2='1320.2' y2='775.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1320.2' y1='775.5' x2='1302.1' y2='751.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1302.1' y1='751.6' x2='1300.3' y2='749.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1286.2" y="758.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(52.9,1286.2,758.7)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="1" id="G726E_rsID_rs757492005_1_110" sift="0">p.G726E</text>
<line x1='4362.4' y1='5040.4' x2='4364.1' y2='5042.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4364.1' y1='5042.9' x2='4380.8' y2='5067.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4380.8' y1='5067.9' x2='4382.4' y2='5070.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4368.8" y="5080.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(56.3,4368.8,5080.6)" sift="1" id="G326E_rsID_rs759579097_1_125" polyphen2="0.075" dbsource="dbSNP" ipvMAF="NA" class="mut">p.G326E</text>
<line x1='1923.8' y1='795.1' x2='1922.5' y2='792.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1922.5' y1='792.4' x2='1909.4' y2='765.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1909.4' y1='765.5' x2='1908.0' y2='762.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1892.4" y="769.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(64.0,1892.4,769.4)" sift="0" id="G751E_rsID_rs761405491_1_130" polyphen2="0.851" dbsource="dbSNP" ipvMAF="NA" class="mut">p.G751E</text>
<line x1='755.0' y1='2010.3' x2='752.2' y2='2009.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='752.2' y1='2009.1' x2='724.8' y2='1997.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='724.8' y1='1997.0' x2='722.0' y2='1995.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="714.3" y="2010.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(23.8,714.3,2010.9)" sift="0.11" id="N660S_rsID_rs761507256_1_133" polyphen2="0.118" class="mut" dbsource="dbSNP" ipvMAF="NA">p.N660S</text>
<line x1='5451.2' y1='2894.0' x2='5454.2' y2='2893.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5454.2' y1='2893.9' x2='5484.2' y2='2892.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5484.2' y1='2892.6' x2='5487.2' y2='2892.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5488.9" y="2909.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(357.5,5488.9,2909.4)" id="A193E_rsID_rs762219565_1_138" sift="0.07" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.149">p.A193E</text>
<line x1='2245.5' y1='491.5' x2='2244.6' y2='488.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2244.6' y1='488.6' x2='2236.0' y2='459.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2236.0' y1='459.9' x2='2235.1' y2='457.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2218.5" y="461.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(73.3,2218.5,461.0)" polyphen2="0" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.85" id="N772S_rsID_rs764682532_1_147">p.N772S</text>
<line x1='2098.9' y1='5455.4' x2='2097.8' y2='5458.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2097.8' y1='5458.2' x2='2087.5' y2='5486.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2087.5' y1='5486.3' x2='2086.5' y2='5489.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2102.1" y="5495.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-69.8,2102.1,5495.9)" sift="0" id="G448E_rsID_rs763655186_1_152" polyphen2="1" class="mut" ipvMAF="NA" dbsource="dbSNP">p.G448E</text>
<line x1='3510.6' y1='5577.4' x2='3511.2' y2='5580.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3511.2' y1='5580.3' x2='3517.0' y2='5609.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3517.0' y1='5609.8' x2='3517.6' y2='5612.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3501.1" y="5617.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(78.8,3501.1,5617.0)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="1" id="G377E_rsID_rs767462182_1_161" sift="0">p.G377E</text>
<line x1='4348.4' y1='5445.4' x2='4349.9' y2='5448.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4349.9' y1='5448.0' x2='4364.4' y2='5474.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4364.4' y1='5474.3' x2='4365.8' y2='5476.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4351.4" y="5485.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(61.1,4351.4,5485.9)" sift="0.43" id="G337E_rsID_rs865959788_1_235" polyphen2="0.023" class="mut" dbsource="dbSNP" ipvMAF="NA">p.G337E</text>
<line x1='4329.5' y1='5455.7' x2='4331.0' y2='5458.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4331.0' y1='5458.3' x2='4331.0' y2='5492.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4331.0' y1='5492.3' x2='4332.5' y2='5495.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4317.9" y="5503.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(61.9,4317.9,5503.8)" id="N338S_rsID_rs916715573_1_242" sift="0.01" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.01">p.N338S</text>
<line x1='5537.2' y1='2348.5' x2='5540.1' y2='2347.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5540.1' y1='2347.8' x2='5569.2' y2='2340.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5569.2' y1='2340.3' x2='5572.1' y2='2339.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5577.2" y="2355.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(345.6,5577.2,2355.8)" polyphen2="0.905" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="E166G_rsID_rs954282708_1_248">p.E166G</text>
<line x1='1092.4' y1='971.6' x2='1090.3' y2='969.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1090.3' y1='969.4' x2='1069.8' y2='947.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1069.8' y1='947.5' x2='1067.7' y2='945.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1054.7" y="956.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(46.8,1054.7,956.3)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.29" id="N712S_rsID_rs1173472683_1_282" sift="0.07">p.N712S</text>
<line x1='811.6' y1='1890.6' x2='809.0' y2='1889.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='809.0' y1='1889.3' x2='782.2' y2='1875.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='782.2' y1='1875.7' x2='779.5' y2='1874.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="771.0" y="1889.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(26.9,771.0,1889.1)" polyphen2="0.001" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.53" id="E667V_rsID_rs1192635576_1_294">p.E667V</text>
<line x1='5614.3' y1='2967.6' x2='5617.3' y2='2967.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5617.3' y1='2967.6' x2='5647.4' y2='2982.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5647.4' y1='2982.3' x2='5650.4' y2='2982.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5651.5" y="2999.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(359.6,5651.5,2999.3)" id="E197G_rsID_rs1271221183_1_331" sift="0.08" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.185">p.E197G</text>
<line x1='2950.3' y1='5453.0' x2='2950.2' y2='5456.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2950.2' y1='5456.0' x2='2949.6' y2='5486.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2949.6' y1='5486.0' x2='2949.6' y2='5489.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2966.5" y="5490.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-88.8,2966.5,5490.3)" sift="0" id="G405E_rsID_rs1418150776_1_404" polyphen2="0.999" dbsource="dbSNP" ipvMAF="NA" class="mut">p.G405E</text>
<line x1='567.9' y1='3323.2' x2='564.9' y2='3323.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='564.9' y1='3323.6' x2='530.9' y2='3293.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='530.9' y1='3293.3' x2='527.9' y2='3293.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="529.0" y="3310.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-6.8,529.0,3310.7)" sift="0.04" id="E589G_rsID_rs1481648983_1_439" polyphen2="0.386" dbsource="dbSNP" ipvMAF="NA" class="mut">p.E589G</text>
<line x1='906.7' y1='1420.2' x2='904.3' y2='1418.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='904.3' y1='1418.4' x2='888.2' y2='1390.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='888.2' y1='1390.0' x2='885.8' y2='1388.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="874.8" y="1401.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(37.3,874.8,1401.1)" polyphen2="0.059" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.09" id="N690S_rsID_rs1569235723_1_442">p.N690S</text>
<line x1='725.5' y1='2080.0' x2='722.8' y2='2078.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='722.8' y1='2078.8' x2='694.9' y2='2067.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='694.9' y1='2067.6' x2='692.2' y2='2066.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="684.9" y="2081.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(22.0,684.9,2081.9)" polyphen2="NA" class="mut" ipvMAF="0.000265" dbsource="dbSNP" sift="NA" id="L656X_rsID_rs199951323_1_5">p.L656X</text>
<line x1='551.0' y1='2851.4' x2='548.0' y2='2851.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='548.0' y1='2851.2' x2='518.1' y2='2849.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='518.1' y1='2849.4' x2='515.1' y2='2849.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="513.1" y="2866.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(3.5,513.1,2866.1)" sift="1" id="A614S_rsID_rs201715513_1_7" polyphen2="0" class="mut" dbsource="dbSNP" ipvMAF="NA">p.A614S</text>
<line x1='5241.0' y1='1643.6' x2='5243.5' y2='1642.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5243.5' y1='1642.0' x2='5269.2' y2='1626.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5269.2' y1='1626.5' x2='5271.8' y2='1625.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5281.4" y="1639.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(328.8,5281.4,1639.0)" polyphen2="0.427" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="S128T_rsID_rs751227277_1_66">p.S128T</text>
<line x1='5568.6' y1='2486.3' x2='5571.6' y2='2485.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5571.6' y1='2485.7' x2='5603.9' y2='2494.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5603.9' y1='2494.7' x2='5606.9' y2='2494.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5611.0" y="2510.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(349.0,5611.0,2510.6)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.876" id="G173S_rsID_rs754511501_1_73" sift="0.01">p.G173S</text>
<line x1='555.5' y1='3210.4' x2='552.5' y2='3210.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='552.5' y1='3210.6' x2='522.7' y2='3213.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='522.7' y1='3213.2' x2='519.7' y2='3213.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="520.2" y="3230.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-4.9,520.2,3230.5)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="1" id="L595V_rsID_rs148036434_1_104" sift="0">p.L595V</text>
<line x1='2119.3' y1='5290.0' x2='2118.2' y2='5292.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2118.2' y1='5292.8' x2='2107.4' y2='5320.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2107.4' y1='5320.8' x2='2106.3' y2='5323.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2121.9" y="5330.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-69.0,2121.9,5330.6)" polyphen2="0.864" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.04" id="L450V_rsID_rs760321012_1_122">p.L450V</text>
<line x1='856.0' y1='1807.1' x2='853.4' y2='1805.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='853.4' y1='1805.7' x2='834.1' y2='1778.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='834.1' y1='1778.7' x2='831.5' y2='1777.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="822.3" y="1791.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(29.4,822.3,1791.6)" sift="0.04" id="V672L_rsID_rs763939235_1_144" polyphen2="0.026" class="mut" ipvMAF="NA" dbsource="dbSNP">p.V672L</text>
<line x1='5582.0' y1='3429.7' x2='5584.9' y2='3430.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5584.9' y1='3430.2' x2='5612.0' y2='3450.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5612.0' y1='3450.1' x2='5615.0' y2='3450.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5613.0" y="3467.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(9.8,5613.0,3467.5)" polyphen2="0" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.26" id="G220S_rsID_rs774621083_1_197">p.G220S</text>
<line x1='5446.6' y1='3935.9' x2='5449.4' y2='3937.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5449.4' y1='3937.0' x2='5477.4' y2='3947.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5477.4' y1='3947.7' x2='5480.2' y2='3948.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5475.0" y="3965.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(20.9,5475.0,3965.0)" polyphen2="0.011" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.08" id="A246S_rsID_rs775542703_1_201">p.A246S</text>
<line x1='2172.5' y1='5309.7' x2='2171.4' y2='5312.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2171.4' y1='5312.6' x2='2148.0' y2='5336.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2148.0' y1='5336.0' x2='2147.0' y2='5338.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2162.1" y="5345.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-70.0,2162.1,5345.3)" sift="0" id="V447F_rsID_rs776328956_1_208" polyphen2="0.981" class="mut" dbsource="dbSNP" ipvMAF="NA">p.V447F</text>
<line x1='4336.5' y1='5256.4' x2='4338.1' y2='5258.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4338.1' y1='5258.9' x2='4353.4' y2='5284.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4353.4' y1='5284.8' x2='4354.9' y2='5287.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4340.7" y="5296.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(59.4,4340.7,5296.8)" polyphen2="0.839" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="L333V_rsID_rs777626602_1_213">p.L333V</text>
<line x1='1199.3' y1='1333.5' x2='1197.1' y2='1331.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1197.1' y1='1331.5' x2='1175.1' y2='1311.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1175.1' y1='1311.1' x2='1172.9' y2='1309.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1160.6" y="1320.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(42.8,1160.6,1320.9)" polyphen2="0.944" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.02" id="A703S_rsID_rs780128908_1_223">p.A703S</text>
<line x1='1873.1' y1='820.6' x2='1871.8' y2='817.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1871.8' y1='817.9' x2='1858.0' y2='791.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1858.0' y1='791.3' x2='1856.6' y2='788.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1841.1" y="795.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(62.7,1841.1,795.6)" id="V748F_rsID_rs947732783_1_247" sift="0.04" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.937">p.V748F</text>
<line x1='830.1' y1='4467.5' x2='827.6' y2='4469.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='827.6' y1='4469.1' x2='802.8' y2='4485.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='802.8' y1='4485.9' x2='800.3' y2='4487.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="809.0" y="4502.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-34.1,809.0,4502.2)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.984" id="L529V_rsID_rs956890785_1_250" sift="0.01">p.L529V</text>
<line x1='2775.2' y1='556.8' x2='2774.9' y2='553.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2774.9' y1='553.8' x2='2772.2' y2='524.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2772.2' y1='524.0' x2='2771.9' y2='521.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2754.9" y="521.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(84.7,2754.9,521.6)" polyphen2="0" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="1" id="T798S_rsID_rs1173491905_1_283">p.T798S</text>
<line x1='4952.3' y1='4486.0' x2='4954.7' y2='4487.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4954.7' y1='4487.8' x2='4978.6' y2='4506.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4978.6' y1='4506.0' x2='4981.0' y2='4507.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4971.4" y="4521.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(37.3,4971.4,4521.9)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.835" id="V283F_rsID_rs1203006090_1_295" sift="0">p.V283F</text>
<line x1='725.9' y1='1417.5' x2='723.4' y2='1415.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='723.4' y1='1415.8' x2='698.8' y2='1398.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='698.8' y1='1398.7' x2='696.4' y2='1397.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="685.9" y="1410.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(34.8,685.9,1410.4)" polyphen2="0.935" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="V685F_rsID_rs1262476548_1_327">p.V685F</text>
<line x1='5695.7' y1='2263.3' x2='5698.5' y2='2262.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5698.5' y1='2262.5' x2='5727.5' y2='2254.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5727.5' y1='2254.6' x2='5730.4' y2='2253.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5735.8" y="2270.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(344.7,5735.8,2270.0)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.595" id="A164S_rsID_rs1316799731_1_353" sift="0.01">p.A164S</text>
<line x1='4972.6' y1='1541.1' x2='4975.0' y2='1539.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4975.0' y1='1539.3' x2='5027.7' y2='1560.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5027.7' y1='1560.9' x2='5030.2' y2='1559.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5040.8" y="1572.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(324.6,5040.8,1572.5)" sift="NA" id="L116X_rsID_rs1340886951_1_362" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.L116X</text>
<line x1='687.4' y1='1494.4' x2='684.9' y2='1492.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='684.9' y1='1492.8' x2='659.8' y2='1476.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='659.8' y1='1476.4' x2='657.2' y2='1474.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="647.2" y="1488.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(33.1,647.2,1488.5)" polyphen2="0.766" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="F681V_rsID_rs1346564574_1_366">p.F681V</text>
<line x1='546.6' y1='2983.7' x2='543.6' y2='2983.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='543.6' y1='2983.7' x2='513.6' y2='2983.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='513.6' y1='2983.5' x2='510.6' y2='2983.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="509.5" y="3000.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(0.4,509.5,3000.4)" id="S607G_rsID_rs1402111758_1_394" sift="0.06" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.018">p.S607G</text>
<line x1='4986.2' y1='4440.4' x2='4988.6' y2='4442.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4988.6' y1='4442.2' x2='5012.9' y2='4459.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5012.9' y1='4459.8' x2='5015.3' y2='4461.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5006.1" y="4475.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(36.0,5006.1,4475.9)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.865" id="S280Y_rsID_rs1451564530_1_424" sift="0.03">p.S280Y</text>
<line x1='398.2' y1='1994.0' x2='395.4' y2='1992.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='395.4' y1='1992.9' x2='367.5' y2='1982.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='367.5' y1='1982.1' x2='364.7' y2='1981.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="357.6" y="1996.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(21.1,357.6,1996.5)" polyphen2="0.994" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="Y654S_rsID_rs1479485636_1_437">p.Y654S</text>
<line x1='5157.4' y1='4168.5' x2='5160.0' y2='4170.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5160.0' y1='4170.0' x2='5186.4' y2='4184.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5186.4' y1='4184.2' x2='5189.0' y2='4185.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5181.7" y="4201.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(28.4,5181.7,4201.1)" polyphen2="1" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="P263S_rsID_rs200745906_1_12">p.P263S</text>
<line x1='5069.0' y1='4600.1' x2='5071.3' y2='4601.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5071.3' y1='4601.9' x2='5095.1' y2='4620.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5095.1' y1='4620.3' x2='5097.4' y2='4622.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5087.8" y="4636.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(37.7,5087.8,4636.1)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.742" id="P284S_rsID_rs267606408_1_15" sift="0">p.P284S</text>
<line x1='588.8' y1='3453.9' x2='585.9' y2='3454.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='585.9' y1='3454.4' x2='556.4' y2='3460.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='556.4' y1='3460.0' x2='553.5' y2='3460.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="555.7" y="3477.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-10.7,555.7,3477.4)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.024" id="R582S_rsID_rs372924787_1_26" sift="0.69">p.R582S</text>
<line x1='1238.3' y1='1292.3' x2='1236.2' y2='1290.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1236.2' y1='1290.2' x2='1214.6' y2='1269.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1214.6' y1='1269.4' x2='1212.5' y2='1267.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1200.0" y="1278.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(44.1,1200.0,1278.8)" id="M706I_rsID_rs372986872_1_27" sift="0.07" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.003">p.M706I</text>
<line x1='498.1' y1='4226.8' x2='495.4' y2='4228.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='495.4' y1='4228.1' x2='483.8' y2='4272.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='483.8' y1='4272.2' x2='481.1' y2='4273.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="488.0" y="4289.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-26.8,488.0,4289.1)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="1" id="S547C_rsID_rs373025684_2_28" sift="0">p.S547C</text>
<line x1='1567.1' y1='1008.4' x2='1565.4' y2='1005.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1565.4' y1='1005.9' x2='1547.9' y2='981.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1547.9' y1='981.6' x2='1546.1' y2='979.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1531.8" y="988.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(54.3,1531.8,988.3)" polyphen2="0.06" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="P729L_rsID_rs375923132_1_36">p.P729L</text>
<line x1='4780.9' y1='4687.6' x2='4783.1' y2='4689.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4783.1' y1='4689.7' x2='4804.9' y2='4710.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4804.9' y1='4710.3' x2='4807.0' y2='4712.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4796.0" y="4725.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(43.5,4796.0,4725.4)" id="M297I_rsID_rs745744395_1_44" sift="0" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.685">p.M297I</text>
<line x1='668.8' y1='3765.1' x2='666.0' y2='3766.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='666.0' y1='3766.0' x2='637.5' y2='3775.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='637.5' y1='3775.4' x2='634.6' y2='3776.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="639.0" y="3792.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-18.2,639.0,3792.7)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.188" id="P565S_rsID_rs750955307_1_58" sift="0.19">p.P565S</text>
<line x1='1644.9' y1='954.6' x2='1643.3' y2='952.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1643.3' y1='952.1' x2='1626.7' y2='927.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1626.7' y1='927.1' x2='1625.1' y2='924.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1610.4" y="933.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(56.5,1610.4,933.2)" polyphen2="1" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="P734L_rsID_rs751484521_1_61">p.P734L</text>
<line x1='1148.8' y1='1389.8' x2='1146.5' y2='1387.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1146.5' y1='1387.9' x2='1123.9' y2='1368.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1123.9' y1='1368.2' x2='1121.6' y2='1366.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1109.7" y="1378.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(41.0,1109.7,1378.4)" sift="NA" id="E699E_rsID_rs113789216_1_89" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.E699E</text>
<line x1='933.7' y1='1390.0' x2='931.3' y2='1388.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='931.3' y1='1388.2' x2='917.0' y2='1357.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='917.0' y1='1357.8' x2='914.6' y2='1355.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="903.4" y="1368.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(38.3,903.4,1368.7)" id="S692P_rsID_rs149039346_1_107" sift="0" dbsource="dbSNP" ipvMAF="0.001325" class="mut" polyphen2="0.723">p.S692P</text>
<line x1='4603.1' y1='4857.3' x2='4605.1' y2='4859.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4605.1' y1='4859.6' x2='4624.7' y2='4882.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4624.7' y1='4882.3' x2='4626.7' y2='4884.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4614.4" y="4896.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(49.2,4614.4,4896.4)" id="E310E_rsID_rs758382603_1_112" sift="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA">p.E310E</text>
<line x1='903.6' y1='1725.4' x2='901.0' y2='1723.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='901.0' y1='1723.8' x2='875.4' y2='1708.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='875.4' y1='1708.2' x2='872.8' y2='1706.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="863.2" y="1720.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(31.3,863.2,1720.7)" polyphen2="0.434" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0" id="P677L_rsID_rs760732432_1_124">p.P677L</text>
<line x1='5372.6' y1='3624.7' x2='5375.6' y2='3625.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5375.6' y1='3625.4' x2='5404.6' y2='3633.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5404.6' y1='3633.1' x2='5407.5' y2='3633.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5404.0" y="3650.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(14.7,5404.0,3650.5)" id="E232E_rsID_rs771188220_1_177" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.E232E</text>
<line x1='246.7' y1='3365.9' x2='243.7' y2='3366.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='243.7' y1='3366.2' x2='214.0' y2='3370.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='214.0' y1='3370.2' x2='211.0' y2='3370.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="212.3" y="3387.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-7.6,212.3,3387.6)" sift="NA" id="E589E_rsID_rs775671955_1_198" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.E589E</text>
<line x1='1966.2' y1='5406.9' x2='1965.0' y2='5409.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1965.0' y1='5409.6' x2='1953.1' y2='5437.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1953.1' y1='5437.2' x2='1952.0' y2='5439.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1966.7" y="5447.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-66.8,1966.7,5447.3)" id="M455I_rsID_rs775744448_1_199" sift="0.01" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.424">p.M455I</text>
<line x1='1958.0' y1='778.8' x2='1956.7' y2='776.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1956.7' y1='776.1' x2='1943.9' y2='748.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1943.9' y1='748.9' x2='1942.7' y2='746.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1926.9" y="752.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(64.9,1926.9,752.6)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.352" id="I753M_rsID_rs776886768_1_210" sift="0">p.I753M</text>
<line x1='1475.2' y1='5128.8' x2='1473.5' y2='5131.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1473.5' y1='5131.2' x2='1445.5' y2='5148.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1445.5' y1='5148.0' x2='1443.7' y2='5150.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1457.0" y="5161.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-54.1,1457.0,5161.2)" sift="0.18" id="E483E_rsID_rs779752560_2_218" polyphen2="0.003" dbsource="dbSNP" ipvMAF="NA" class="mut">p.E483E</text>
<line x1='5422.6' y1='2611.9' x2='5425.6' y2='2611.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5425.6' y1='2611.4' x2='5455.2' y2='2606.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5455.2' y1='2606.7' x2='5458.2' y2='2606.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5461.8" y="2622.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(350.9,5461.8,2622.9)" sift="0" id="P178L_rsID_rs779651019_1_221" polyphen2="0.792" class="mut" dbsource="dbSNP" ipvMAF="NA">p.P178L</text>
<line x1='706.7' y1='3872.0' x2='703.9' y2='3873.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='703.9' y1='3873.1' x2='675.9' y2='3883.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='675.9' y1='3883.8' x2='673.1' y2='3884.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="678.2" y="3901.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-20.8,678.2,3901.1)" id="R559S_rsID_rs1016777825_1_262" sift="0.31" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.001">p.R559S</text>
<line x1='1037.6' y1='1007.7' x2='1035.5' y2='1005.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1035.5' y1='1005.5' x2='1014.4' y2='984.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1014.4' y1='984.2' x2='1012.3' y2='982.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="999.5" y="993.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(45.4,999.5,993.3)" polyphen2="0.372" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.02" id="S709R_rsID_rs1052746182_1_271">p.S709R</text>
<line x1='424.1' y1='3423.5' x2='421.1' y2='3424.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='421.1' y1='3424.0' x2='391.5' y2='3428.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='391.5' y1='3428.8' x2='388.6' y2='3429.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="390.4" y="3446.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-9.3,390.4,3446.2)" polyphen2="0.998" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="L585P_rsID_rs1173089368_1_281">p.L585P</text>
<line x1='2926.8' y1='5615.5' x2='2926.7' y2='5618.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2926.7' y1='5618.5' x2='2925.9' y2='5648.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2925.9' y1='5648.5' x2='2925.8' y2='5651.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2942.8" y="5652.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-88.4,2942.8,5652.9)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="E406E_rsID_rs1184887977_1_290">p.E406E</text>
<line x1='5453.3' y1='2969.6' x2='5456.3' y2='2969.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5456.3' y1='2969.6' x2='5486.4' y2='2983.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5486.4' y1='2983.4' x2='5489.4' y2='2983.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5490.5" y="3000.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(359.6,5490.5,3000.4)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="E197E_rsID_rs1214041216_1_303" sift="NA">p.E197E</text>
<line x1='1325.6' y1='5024.9' x2='1323.7' y2='5027.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1323.7' y1='5027.2' x2='1304.6' y2='5050.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1304.6' y1='5050.3' x2='1302.7' y2='5052.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1315.2" y="5064.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-50.4,1315.2,5064.2)" sift="0.06" id="P492S_rsID_rs1221577570_1_305" polyphen2="0.387" dbsource="dbSNP" ipvMAF="NA" class="mut">p.P492S</text>
<line x1='2366.1' y1='629.8' x2='2365.3' y2='626.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2365.3' y1='626.9' x2='2385.0' y2='590.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2385.0' y1='590.8' x2='2384.3' y2='587.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2367.6" y="591.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(75.7,2367.6,591.1)" polyphen2="0" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.58" id="S776R_rsID_rs1228927272_1_309">p.S776R</text>
<line x1='1741.0' y1='894.2' x2='1739.4' y2='891.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1739.4' y1='891.6' x2='1724.0' y2='865.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1724.0' y1='865.9' x2='1722.5' y2='863.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1707.4" y="871.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(59.1,1707.4,871.2)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0" id="S740P_rsID_rs1259850376_1_325" sift="0.01">p.S740P</text>
<line x1='2077.8' y1='5637.9' x2='2076.8' y2='5640.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2076.8' y1='5640.8' x2='2066.9' y2='5669.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2066.9' y1='5669.1' x2='2065.9' y2='5671.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2081.6" y="5678.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-70.7,2081.6,5678.4)" sift="0.12" id="I446M_rsID_rs1290769028_1_337" polyphen2="0.514" ipvMAF="NA" dbsource="dbSNP" class="mut">p.I446M</text>
<line x1='877.2' y1='4230.3' x2='874.6' y2='4231.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='874.6' y1='4231.8' x2='848.7' y2='4246.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='848.7' y1='4246.8' x2='846.1' y2='4248.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="853.8" y="4263.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-30.1,853.8,4263.5)" sift="0.02" id="P538L_rsID_rs1315545082_1_350" polyphen2="0.371" class="mut" dbsource="dbSNP" ipvMAF="NA">p.P538L</text>
<line x1='2667.6' y1='5430.9' x2='2667.2' y2='5433.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2667.2' y1='5433.9' x2='2649.1' y2='5461.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2649.1' y1='5461.6' x2='2648.6' y2='5464.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2665.3" y="5467.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-81.9,2665.3,5467.9)" sift="0.01" id="S420P_rsID_rs1384237654_1_382" polyphen2="0.022" class="mut" dbsource="dbSNP" ipvMAF="NA">p.S420P</text>
<line x1='1476.6' y1='1076.8' x2='1474.7' y2='1074.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1474.7' y1='1074.4' x2='1456.1' y2='1050.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1456.1' y1='1050.9' x2='1454.2' y2='1048.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1440.3" y="1058.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(51.6,1440.3,1058.4)" id="E723E_rsID_rs1384877595_1_383" sift="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="NA">p.E723E</text>
<line x1='5695.1' y1='2308.0' x2='5698.0' y2='2307.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5698.0' y1='2307.2' x2='5727.0' y2='2299.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5727.0' y1='2299.8' x2='5729.9' y2='2299.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5735.1" y="2315.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(345.6,5735.1,2315.2)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="E166E_rsID_rs1391829986_1_387" sift="NA">p.E166E</text>
<line x1='4032.9' y1='5225.5' x2='4034.2' y2='5228.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4034.2' y1='5228.2' x2='4046.8' y2='5255.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4046.8' y1='5255.4' x2='4048.1' y2='5258.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4033.1" y="5266.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(65.1,4033.1,5266.1)" polyphen2="0.975" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0.11" id="P346S_rsID_rs1410274315_1_399">p.P346S</text>
<line x1='1692.6' y1='923.9' x2='1691.0' y2='921.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1691.0' y1='921.3' x2='1675.0' y2='895.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1675.0' y1='895.9' x2='1673.4' y2='893.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1658.5" y="901.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(57.8,1658.5,901.7)" id="P737S_rsID_rs1416534293_1_402" sift="0.14" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.035">p.P737S</text>
<line x1='2445.7' y1='5563.2' x2='2445.0' y2='5566.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2445.0' y1='5566.2' x2='2438.7' y2='5595.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2438.7' y1='5595.5' x2='2438.0' y2='5598.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2454.5" y="5602.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-77.8,2454.5,5602.9)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="E430E_rsID_rs1448548701_1_421" sift="NA">p.E430E</text>
<line x1='2681.2' y1='567.3' x2='2680.8' y2='564.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2680.8' y1='564.3' x2='2676.9' y2='534.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2676.9' y1='534.6' x2='2676.5' y2='531.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2659.6" y="532.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(82.5,2659.6,532.9)" id="P793L_rsID_rs1457512583_1_427" sift="0.23" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.003">p.P793L</text>
<line x1='1911.5' y1='5198.8' x2='1910.2' y2='5201.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1910.2' y1='5201.5' x2='1884.2' y2='5222.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1884.2' y1='5222.1' x2='1882.8' y2='5224.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1897.6" y="5233.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-63.3,1897.6,5233.2)" sift="0.18" id="M462I_rsID_rs1463563888_1_430" polyphen2="0.739" ipvMAF="NA" dbsource="dbSNP" class="mut">p.M462I</text>
<line x1='5247.0' y1='2014.7' x2='5249.7' y2='2013.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5249.7' y1='2013.5' x2='5277.2' y2='2001.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5277.2' y1='2001.5' x2='5279.9' y2='2000.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5287.6" y="2015.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(336.3,5287.6,2015.5)" id="E145E_rsID_rs1469916451_1_434" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.E145E</text>
<line x1='845.0' y1='1524.9' x2='842.5' y2='1523.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='842.5' y1='1523.2' x2='817.8' y2='1506.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='817.8' y1='1506.3' x2='815.3' y2='1504.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="804.9" y="1518.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(34.4,804.9,1518.1)" id="F684F_rsID_rs770503198_1_171" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.F684F</text>
<line x1='2059.2' y1='569.2' x2='2058.1' y2='566.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2058.1' y1='566.4' x2='2047.3' y2='538.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2047.3' y1='538.4' x2='2046.2' y2='535.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2030.0" y="540.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(68.8,2030.0,540.9)" id="F762F_rsID_rs943387084_1_246" sift="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA">p.F762F</text>
<line x1='547.2' y1='3059.3' x2='544.2' y2='3059.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='544.2' y1='3059.4' x2='514.2' y2='3060.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='514.2' y1='3060.1' x2='511.2' y2='3060.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="510.7" y="3077.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-1.4,510.7,3077.2)" sift="NA" id="F603F_rsID_rs1005566006_1_259" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.F603F</text>
<line x1='1360.9' y1='1174.3' x2='1358.9' y2='1172.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1358.9' y1='1172.1' x2='1338.9' y2='1149.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1338.9' y1='1149.8' x2='1336.9' y2='1147.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1323.6" y="1158.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(48.1,1323.6,1158.2)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA" id="F715F_rsID_rs1174145055_1_284" sift="NA">p.F715F</text>
<line x1='498.1' y1='4226.8' x2='495.4' y2='4228.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='495.4' y1='4228.1' x2='468.4' y2='4241.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='468.4' y1='4241.3' x2='465.7' y2='4242.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="472.4" y="4258.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-26.1,472.4,4258.3)" sift="0" id="S547F_rsID_rs373025684_1_28" polyphen2="1" ipvMAF="NA" dbsource="dbSNP" class="mut">p.S547F</text>
<line x1='1410.6' y1='717.4' x2='1408.9' y2='714.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1408.9' y1='714.9' x2='1404.9' y2='681.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1404.9' y1='681.1' x2='1403.2' y2='678.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1388.7" y="687.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(55.5,1388.7,687.5)" dbsource="dbSNP" ipvMAF="0.004768" class="mut" polyphen2="0.941" id="L731F_rsID_rs147311723_1_101" sift="0">p.L731F</text>
<line x1='809.0' y1='1597.5' x2='806.4' y2='1595.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='806.4' y1='1595.8' x2='781.2' y2='1579.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='781.2' y1='1579.7' x2='778.6' y2='1578.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="768.7" y="1591.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(32.6,768.7,1591.9)" id="S680S_rsID_rs758968315_1_115" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.S680S</text>
<line x1='406.1' y1='3365.0' x2='403.1' y2='3365.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='403.1' y1='3365.5' x2='373.4' y2='3369.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='373.4' y1='3369.6' x2='370.4' y2='3370.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="371.8" y="3387.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-8.0,371.8,3387.0)" polyphen2="1" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="F588S_rsID_rs760929786_1_127">p.F588S</text>
<line x1='4631.6' y1='4832.4' x2='4633.6' y2='4834.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4633.6' y1='4834.6' x2='4653.5' y2='4857.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4653.5' y1='4857.0' x2='4655.5' y2='4859.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4643.4" y="4871.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(48.3,4643.4,4871.3)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.989" id="F308L_rsID_rs766518362_1_157" sift="0.01">p.F308L</text>
<line x1='575.2' y1='2625.8' x2='572.2' y2='2625.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='572.2' y1='2625.3' x2='542.6' y2='2620.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='542.6' y1='2620.7' x2='539.6' y2='2620.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="536.1" y="2636.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(8.8,536.1,2636.9)" sift="NA" id="S626S_rsID_rs769444182_1_175" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.S626S</text>
<line x1='2888.4' y1='549.0' x2='2888.3' y2='546.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2888.3' y1='546.0' x2='2886.9' y2='516.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2886.9' y1='516.1' x2='2886.8' y2='513.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2869.7" y="512.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(87.4,2869.7,512.9)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.962" id="S804F_rsID_rs771107251_1_176" sift="0">p.S804F</text>
<line x1='964.7' y1='1629.8' x2='962.3' y2='1628.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='962.3' y1='1628.1' x2='937.4' y2='1611.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='937.4' y1='1611.4' x2='934.9' y2='1609.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="924.6" y="1623.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(33.9,924.6,1623.3)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.026" id="F683L_rsID_rs773848804_1_192" sift="0.18">p.F683L</text>
<line x1='2001.8' y1='420.9' x2='2000.7' y2='418.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2000.7' y1='418.1' x2='1989.9' y2='390.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1989.9' y1='390.1' x2='1988.8' y2='387.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1972.6" y="392.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(68.8,1972.6,392.6)" sift="NA" id="F762L_rsID_rs943387084_2_246" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.F762L</text>
<line x1='734.7' y1='3942.3' x2='731.9' y2='3943.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='731.9' y1='3943.5' x2='704.2' y2='3955.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='704.2' y1='3955.0' x2='701.4' y2='3956.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="706.9" y="3971.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-22.6,706.9,3971.7)" id="F555L_rsID_rs961465783_1_253" sift="0.44" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0">p.F555L</text>
<line x1='1033.4' y1='4467.0' x2='1031.0' y2='4468.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1031.0' y1='4468.8' x2='1006.9' y2='4486.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1006.9' y1='4486.7' x2='1004.5' y2='4488.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1013.9" y="4502.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-36.7,1013.9,4502.7)" id="F523L_rsID_rs1019324840_1_263" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.997">p.F523L</text>
<line x1='3044.8' y1='5453.1' x2='3044.9' y2='5456.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3044.9' y1='5456.1' x2='3045.4' y2='5486.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3045.4' y1='5486.1' x2='3045.5' y2='5489.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3028.5" y="5490.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(89.0,3028.5,5490.3)" polyphen2="0.988" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="F400L_rsID_rs1214851578_1_304">p.F400L</text>
<line x1='2494.8' y1='599.1' x2='2494.2' y2='596.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2494.2' y1='596.1' x2='2501.9' y2='563.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2501.9' y1='563.9' x2='2501.3' y2='561.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2484.5" y="563.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(78.4,2484.5,563.4)" sift="0.07" id="S783F_rsID_rs1258561133_1_324" polyphen2="0.003" dbsource="dbSNP" ipvMAF="NA" class="mut">p.S783F</text>
<line x1='1052.6' y1='4955.1' x2='1050.4' y2='4957.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1050.4' y1='4957.2' x2='1029.3' y2='4978.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1029.3' y1='4978.5' x2='1027.2' y2='4980.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1038.5" y="4993.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-45.1,1038.5,4993.3)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.904" id="F504L_rsID_rs1285805675_1_335" sift="0">p.F504L</text>
<line x1='1658.3' y1='756.0' x2='1656.8' y2='753.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1656.8' y1='753.4' x2='1641.4' y2='727.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1641.4' y1='727.7' x2='1639.9' y2='725.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1624.8" y="733.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(59.1,1624.8,733.0)" sift="0" id="S740F_rsID_rs1371764870_1_380" polyphen2="0.082" class="mut" ipvMAF="NA" dbsource="dbSNP">p.S740F</text>
<line x1='1052.5' y1='4754.8' x2='1050.2' y2='4756.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1050.2' y1='4756.8' x2='1028.0' y2='4776.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1028.0' y1='4776.9' x2='1025.7' y2='4778.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1036.4" y="4792.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-42.0,1036.4,4792.2)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="S511S_rsID_rs1443937359_1_415">p.S511S</text>
<line x1='2705.1' y1='5435.7' x2='2704.8' y2='5438.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2704.8' y1='5438.7' x2='2701.1' y2='5468.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2701.1' y1='5468.5' x2='2700.8' y2='5471.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2717.6" y="5474.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-83.1,2717.6,5474.4)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="L418L_rsID_rs200995847_1_10">p.L418L</text>
<line x1='5105.4' y1='4551.8' x2='5107.8' y2='4553.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5107.8' y1='4553.6' x2='5132.0' y2='4571.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5132.0' y1='4571.4' x2='5134.4' y2='4573.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5125.1" y="4587.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(36.4,5125.1,4587.4)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA" id="L281L_rsID_rs202032109_1_17" sift="NA">p.L281L</text>
<line x1='680.9' y1='3800.9' x2='678.1' y2='3801.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='678.1' y1='3801.9' x2='649.7' y2='3811.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='649.7' y1='3811.7' x2='646.9' y2='3812.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="651.5" y="3829.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-19.1,651.5,3829.0)" id="S563L_rsID_rs375352455_1_35" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.997">p.S563L</text>
<line x1='1282.0' y1='4751.6' x2='1279.9' y2='4753.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1279.9' y1='4753.7' x2='1258.9' y2='4775.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1258.9' y1='4775.1' x2='1256.8' y2='4777.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1268.2" y="4789.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-45.6,1268.2,4789.9)" sift="NA" id="L503L_rsID_rs748701949_1_52" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="0.000265">p.L503L</text>
<line x1='5441.9' y1='2762.0' x2='5444.9' y2='2761.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5444.9' y1='2761.7' x2='5474.8' y2='2758.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5474.8' y1='2758.8' x2='5477.8' y2='2758.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5480.3" y="2775.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(354.4,5480.3,2775.3)" sift="0" id="L186S_rsID_rs750052167_1_55" polyphen2="0.996" class="mut" dbsource="dbSNP" ipvMAF="NA">p.L186S</text>
<line x1='3946.4' y1='5263.6' x2='3947.6' y2='5266.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3947.6' y1='5266.4' x2='3959.1' y2='5294.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3959.1' y1='5294.1' x2='3960.3' y2='5296.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3945.0" y="5304.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(67.3,3945.0,5304.3)" id="L351L_rsID_rs147464721_1_102" sift="NA" class="mut" ipvMAF="0.001589" dbsource="dbSNP" polyphen2="NA">p.L351L</text>
<line x1='1790.0' y1='865.6' x2='1788.5' y2='863.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1788.5' y1='863.0' x2='1773.7' y2='836.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1773.7' y1='836.9' x2='1772.2' y2='834.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1757.0" y="841.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(60.5,1757.0,841.9)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="L743L_rsID_rs762444602_1_137">p.L743L</text>
<line x1='401.3' y1='3304.6' x2='398.3' y2='3305.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='398.3' y1='3305.0' x2='368.5' y2='3308.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='368.5' y1='3308.5' x2='365.5' y2='3308.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="366.6" y="3325.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-6.7,366.6,3325.8)" id="L591L_rsID_rs776189364_1_206" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.L591L</text>
<line x1='582.1' y1='3416.7' x2='579.2' y2='3417.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='579.2' y1='3417.2' x2='549.6' y2='3422.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='549.6' y1='3422.3' x2='546.7' y2='3422.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="548.6" y="3439.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-9.8,548.6,3439.7)" id="L584L_rsID_rs776791252_1_209" sift="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="NA">p.L584L</text>
<line x1='3605.9' y1='5377.5' x2='3606.7' y2='5380.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3606.7' y1='5380.4' x2='3614.1' y2='5409.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3614.1' y1='5409.5' x2='3614.8' y2='5412.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3598.6" y="5417.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(75.7,3598.6,5417.5)" sift="NA" id="L370L_rsID_rs779083203_1_215" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.L370L</text>
<line x1='2316.4' y1='5356.3' x2='2315.5' y2='5359.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2315.5' y1='5359.2' x2='2307.2' y2='5388.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2307.2' y1='5388.0' x2='2306.4' y2='5390.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2322.4" y="5396.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-73.8,2322.4,5396.6)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="L439L_rsID_rs964898848_1_254" sift="NA">p.L439L</text>
<line x1='2253.3' y1='5501.4' x2='2252.5' y2='5504.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2252.5' y1='5504.3' x2='2243.9' y2='5533.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2243.9' y1='5533.1' x2='2243.0' y2='5535.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2259.1" y="5541.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-73.4,2259.1,5541.7)" sift="NA" id="L440L_rsID_rs1017439564_1_264" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.L440L</text>
<line x1='492.9' y1='3759.1' x2='490.0' y2='3759.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='490.0' y1='3759.9' x2='461.3' y2='3768.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='461.3' y1='3768.6' x2='458.4' y2='3769.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="462.5" y="3786.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-16.8,462.5,3786.0)" sift="NA" id="L568L_rsID_rs1029163828_1_266" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.L568L</text>
<line x1='4007.0' y1='5408.5' x2='4008.1' y2='5411.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4008.1' y1='5411.2' x2='4019.7' y2='5438.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4019.7' y1='5438.9' x2='4020.9' y2='5441.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4005.5" y="5449.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(67.3,4005.5,5449.1)" sift="NA" id="L351L_rsID_rs1035663418_1_267" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.L351L</text>
<line x1='4979.9' y1='1284.8' x2='4982.2' y2='1282.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4982.2' y1='1282.9' x2='5004.8' y2='1263.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5004.8' y1='1263.2' x2='5007.1' y2='1261.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5018.9" y="1273.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(319.1,5018.9,1273.5)" polyphen2="0.101" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.02" id="S106L_rsID_rs1038445507_1_268">p.S106L</text>
<line x1='394.1' y1='3224.3' x2='391.1' y2='3224.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='391.1' y1='3224.5' x2='361.3' y2='3227.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='361.3' y1='3227.1' x2='358.3' y2='3227.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="358.8" y="3244.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-4.9,358.8,3244.4)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="L595L_rsID_rs1184569811_1_289">p.L595L</text>
<line x1='5584.7' y1='2606.4' x2='5587.7' y2='2605.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5587.7' y1='2605.9' x2='5617.3' y2='2601.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5617.3' y1='2601.4' x2='5620.3' y2='2600.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5623.8" y="2617.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(351.3,5623.8,2617.6)" id="L179L_rsID_rs1192307729_1_292" sift="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA">p.L179L</text>
<line x1='5239.6' y1='1343.7' x2='5242.0' y2='1341.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5242.0' y1='1341.9' x2='5275.6' y2='1337.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5275.6' y1='1337.0' x2='5278.0' y2='1335.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5288.8" y="1348.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(323.8,5288.8,1348.4)" id="L116L_rsID_rs1209189779_1_300" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.L116L</text>
<line x1='4419.1' y1='5395.7' x2='4420.6' y2='5398.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4420.6' y1='5398.3' x2='4435.9' y2='5424.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4435.9' y1='5424.1' x2='4437.4' y2='5426.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4423.3" y="5436.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(59.4,4423.3,5436.2)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="L333L_rsID_rs1253786077_1_321">p.L333L</text>
<line x1='641.1' y1='3674.7' x2='638.2' y2='3675.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='638.2' y1='3675.5' x2='609.4' y2='3683.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='609.4' y1='3683.7' x2='606.5' y2='3684.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="610.2" y="3701.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-16.0,610.2,3701.2)" polyphen2="0.999" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0" id="L570S_rsID_rs1305384714_1_345">p.L570S</text>
<line x1='4778.2' y1='1309.5' x2='4780.3' y2='1307.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4780.3' y1='1307.4' x2='4802.1' y2='1286.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4802.1' y1='1286.8' x2='4804.3' y2='1284.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4816.6" y="1296.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(316.4,4816.6,1296.4)" sift="NA" id="L100L_rsID_rs1390680136_1_385" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.L100L</text>
<line x1='2686.2' y1='5591.6' x2='2685.9' y2='5594.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2685.9' y1='5594.6' x2='2682.3' y2='5624.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2682.3' y1='5624.3' x2='2681.9' y2='5627.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2698.7" y="5630.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-83.1,2698.7,5630.3)" id="L418S_rsID_rs1466701781_1_433" sift="0" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.999">p.L418S</text>
<line x1='5734.4' y1='3498.6' x2='5737.4' y2='3499.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5737.4' y1='3499.1' x2='5766.9' y2='3504.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5766.9' y1='3504.5' x2='5769.8' y2='3505.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5767.7" y="3521.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(10.3,5767.7,3521.9)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="L222L_rsID_rs1479566186_1_438">p.L222L</text>
<line x1='4214.3' y1='868.0' x2='4215.7' y2='865.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4215.7' y1='865.4' x2='4230.6' y2='839.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4230.6' y1='839.4' x2='4232.1' y2='836.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4247.3" y="844.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(299.7,4247.3,844.4)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.104" id="M62V_rsID_rs1325542104_1_354" sift="0.08">p.M62V</text>
<line x1='5109.1' y1='4821.1' x2='5111.3' y2='4823.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5111.3' y1='4823.1' x2='5134.1' y2='4842.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5134.1' y1='4842.7' x2='5136.3' y2='4844.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5125.9" y="4858.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(40.8,5125.9,4858.1)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.993" id="I291K_rsID_rs756358940_1_79" sift="0.01">p.I291K</text>
<line x1='671.8' y1='4209.2' x2='669.1' y2='4210.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='669.1' y1='4210.5' x2='642.5' y2='4224.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='642.5' y1='4224.4' x2='639.8' y2='4225.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="646.6" y="4240.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-27.4,646.6,4240.8)" id="I544N_rsID_rs769821600_1_174" sift="0" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="1">p.I544N</text>
<line x1='5523.1' y1='3685.1' x2='5526.0' y2='3685.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5526.0' y1='3685.9' x2='5555.0' y2='3693.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5555.0' y1='3693.8' x2='5557.9' y2='3694.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5554.3" y="3711.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(15.2,5554.3,3711.2)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.993" id="I233N_rsID_rs868538858_1_233" sift="0">p.I233N</text>
<line x1='849.4' y1='4180.9' x2='846.7' y2='4182.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='846.7' y1='4182.3' x2='820.4' y2='4196.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='820.4' y1='4196.7' x2='817.8' y2='4198.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="825.2" y="4213.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-28.8,825.2,4213.5)" polyphen2="0.958" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="K541I_rsID_rs889263894_1_238">p.K541I</text>
<line x1='381.5' y1='3144.2' x2='378.5' y2='3144.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='378.5' y1='3144.4' x2='348.5' y2='3146.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='348.5' y1='3146.0' x2='345.5' y2='3146.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="345.5" y="3163.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-3.2,345.5,3163.2)" polyphen2="0.987" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0" id="N599I_rsID_rs1423289421_1_407">p.N599I</text>
<line x1='1811.0' y1='5146.1' x2='1809.5' y2='5148.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1809.5' y1='5148.8' x2='1782.6' y2='5168.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1782.6' y1='5168.1' x2='1781.1' y2='5170.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1795.5" y="5179.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-60.7,1795.5,5179.9)" sift="0.02" id="I468V_rsID_rs191860450_1_2" polyphen2="0.747" class="mut" dbsource="dbSNP" ipvMAF="0.00053">p.I468V</text>
<line x1='1595.6' y1='609.5' x2='1594.1' y2='606.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1594.1' y1='606.9' x2='1578.9' y2='581.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1578.9' y1='581.0' x2='1577.4' y2='578.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1562.3" y="586.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(59.6,1562.3,586.2)" sift="0.64" id="I741V_rsID_rs372923812_1_25" polyphen2="0.003" class="mut" ipvMAF="NA" dbsource="dbSNP">p.I741V</text>
<line x1='2096.8' y1='718.8' x2='2095.7' y2='716.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2095.7' y1='716.0' x2='2084.7' y2='688.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2084.7' y1='688.1' x2='2083.6' y2='685.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2067.4" y="690.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(68.4,2067.4,690.7)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.024" id="I761V_rsID_rs769030917_1_168" sift="0.21">p.I761V</text>
<line x1='1822.0' y1='5334.1' x2='1820.7' y2='5336.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1820.7' y1='5336.8' x2='1807.2' y2='5363.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1807.2' y1='5363.6' x2='1805.8' y2='5366.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1820.6" y="5374.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-63.2,1820.6,5374.7)" polyphen2="0.503" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="0.03" id="V463I_rsID_rs772445388_1_181">p.V463I</text>
<line x1='1823.0' y1='847.2' x2='1821.6' y2='844.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1821.6' y1='844.6' x2='1807.2' y2='818.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1807.2' y1='818.3' x2='1805.8' y2='815.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1790.8" y="822.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(61.3,1790.8,822.7)" polyphen2="0.007" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="0.33" id="V745I_rsID_rs772641644_1_187">p.V745I</text>
<line x1='4253.5' y1='718.1' x2='4254.9' y2='715.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4254.9' y1='715.5' x2='4269.3' y2='689.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4269.3' y1='689.2' x2='4270.8' y2='686.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4286.1" y="693.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(298.8,4286.1,693.9)" sift="NA" id="Q60Q_rsID_rs774593309_1_196" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.Q60Q</text>
<line x1='5029.6' y1='4378.5' x2='5032.1' y2='4380.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5032.1' y1='4380.2' x2='5056.9' y2='4397.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5056.9' y1='4397.0' x2='5059.4' y2='4398.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5050.6" y="4413.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(34.2,5050.6,4413.3)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.311" id="T276I_rsID_rs866821244_1_229" sift="0.06">p.T276I</text>
<line x1='2026.9' y1='747.7' x2='2025.7' y2='745.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2025.7' y1='745.0' x2='2013.8' y2='717.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2013.8' y1='717.4' x2='2012.7' y2='714.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1997.1" y="720.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(66.6,1997.1,720.3)" sift="0.02" id="I757T_rsID_rs931448406_1_245" polyphen2="0.164" dbsource="dbSNP" ipvMAF="NA" class="mut">p.I757T</text>
<line x1='5192.4' y1='4101.5' x2='5195.0' y2='4102.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5195.0' y1='4102.8' x2='5221.8' y2='4116.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5221.8' y1='4116.3' x2='5224.5' y2='4117.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5217.7" y="4133.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(26.7,5217.7,4133.2)" polyphen2="0" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.99" id="I259T_rsID_rs1161338919_1_274">p.I259T</text>
<line x1='218.8' y1='2960.0' x2='215.8' y2='2960.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='215.8' y1='2960.0' x2='185.8' y2='2959.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='185.8' y1='2959.6' x2='182.8' y2='2959.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="181.6" y="2976.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(0.8,181.6,2976.5)" id="T608I_rsID_rs1201908212_1_296" sift="0.05" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.474">p.T608I</text>
<line x1='5550.8' y1='3608.9' x2='5553.8' y2='3609.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5553.8' y1='3609.6' x2='5582.9' y2='3616.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5582.9' y1='3616.5' x2='5585.9' y2='3617.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5582.8" y="3634.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(13.4,5582.8,3634.0)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.182" id="T229I_rsID_rs1204132218_1_297" sift="0.37">p.T229I</text>
<line x1='1889.6' y1='633.0' x2='1888.3' y2='630.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1888.3' y1='630.3' x2='1875.6' y2='603.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1875.6' y1='603.2' x2='1874.3' y2='600.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1858.5" y="606.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(64.9,1858.5,606.8)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0" id="I753V_rsID_rs1260616687_1_326" sift="1">p.I753V</text>
<line x1='740.0' y1='2045.0' x2='737.2' y2='2043.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='737.2' y1='2043.8' x2='709.6' y2='2032.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='709.6' y1='2032.2' x2='706.8' y2='2031.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="699.3" y="2046.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(22.9,699.3,2046.3)" id="V658I_rsID_rs1295899858_1_339" sift="0.33" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.003">p.V658I</text>
<line x1='5445.6' y1='3196.4' x2='5448.6' y2='3196.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5448.6' y1='3196.6' x2='5478.5' y2='3199.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5478.5' y1='3199.0' x2='5481.5' y2='3199.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5481.1" y="3216.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(4.6,5481.1,3216.3)" id="V209I_rsID_rs1327824339_1_356" sift="0.07" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.055">p.V209I</text>
<line x1='5410.2' y1='3458.7' x2='5413.2' y2='3459.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5413.2' y1='3459.2' x2='5440.0' y2='3478.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5440.0' y1='3478.8' x2='5442.9' y2='3479.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5440.6" y="3496.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(11.1,5440.6,3496.2)" id="I223V_rsID_rs1342472374_1_364" sift="0.35" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.003">p.I223V</text>
<line x1='2625.8' y1='5587.6' x2='2625.4' y2='5590.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2625.4' y1='5590.6' x2='2621.1' y2='5620.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2621.1' y1='5620.2' x2='2620.7' y2='5623.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2637.4" y="5626.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-81.8,2637.4,5626.6)" id="I421T_rsID_rs1352508510_1_371" sift="0.05" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.807">p.I421T</text>
<line x1='4522.3' y1='892.9' x2='4524.1' y2='890.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4524.1' y1='890.5' x2='4541.7' y2='866.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4541.7' y1='866.1' x2='4543.4' y2='863.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4557.7" y="872.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(305.8,4557.7,872.9)" sift="NA" id="Q76Q_rsID_rs1388651717_1_384" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP">p.Q76Q</text>
<line x1='1040.6' y1='1269.0' x2='1038.3' y2='1267.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1038.3' y1='1267.0' x2='1015.9' y2='1247.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1015.9' y1='1247.2' x2='1013.6' y2='1245.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1001.6" y="1257.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(41.5,1001.6,1257.3)" polyphen2="0.906" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="V700I_rsID_rs1392981937_1_388">p.V700I</text>
<line x1='296.6' y1='3683.8' x2='293.7' y2='3684.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='293.7' y1='3684.5' x2='264.6' y2='3691.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='264.6' y1='3691.9' x2='261.7' y2='3692.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="264.9" y="3708.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-14.2,264.9,3708.8)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.021" id="V574I_rsID_rs1406604641_1_397" sift="0.05">p.V574I</text>
<line x1='818.9' y1='4734.1' x2='816.5' y2='4736.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='816.5' y1='4736.0' x2='793.0' y2='4754.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='793.0' y1='4754.7' x2='790.7' y2='4756.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="800.5" y="4770.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-38.5,800.5,4770.4)" polyphen2="0.997" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0.41" id="T519I_rsID_rs1445263977_1_417">p.T519I</text>
<line x1='3729.5' y1='657.4' x2='3730.4' y2='654.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3730.4' y1='654.6' x2='3739.3' y2='625.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3739.3' y1='625.9' x2='3740.2' y2='623.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3756.7" y="627.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(287.3,3756.7,627.2)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="H34H_rsID_rs368655410_1_18">p.H34H</text>
<line x1='4090.2' y1='641.2' x2='4091.4' y2='638.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4091.4' y1='638.5' x2='4104.0' y2='611.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4104.0' y1='611.3' x2='4105.3' y2='608.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4121.1" y="614.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(294.8,4121.1,614.8)" polyphen2="0.599" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.03" id="N51D_rsID_rs760159085_1_136">p.N51D</text>
<line x1='4218.6' y1='698.2' x2='4220.0' y2='695.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4220.0' y1='695.5' x2='4234.0' y2='669.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4234.0' y1='669.0' x2='4235.4' y2='666.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4250.9" y="673.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(297.9,4250.9,673.5)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.984" id="N58D_rsID_rs1222417695_1_307" sift="0">p.N58D</text>
<line x1='4289.7' y1='563.8' x2='4291.1' y2='561.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4291.1' y1='561.2' x2='4305.2' y2='534.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4305.2' y1='534.7' x2='4306.6' y2='532.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4322.0" y="539.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(297.9,4322.0,539.1)" id="N58H_rsID_rs1222417695_2_307" sift="0" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.984">p.N58H</text>
<line x1='4373.7' y1='790.7' x2='4375.2' y2='788.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4375.2' y1='788.2' x2='4391.1' y2='762.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4391.1' y1='762.7' x2='4392.7' y2='760.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4407.6" y="768.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(301.9,4407.6,768.3)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="D67D_rsID_rs1254567742_1_322" sift="NA">p.D67D</text>
<line x1='4147.9' y1='831.6' x2='4149.3' y2='829.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4149.3' y1='829.0' x2='4163.4' y2='802.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4163.4' y1='802.5' x2='4164.8' y2='799.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4180.3" y="806.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(297.9,4180.3,806.9)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.996" id="N58K_rsID_rs771621249_1_178" sift="0">p.N58K</text>
<line x1='4247.0' y1='887.0' x2='4248.5' y2='884.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4248.5' y1='884.4' x2='4263.7' y2='858.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4263.7' y1='858.6' x2='4265.3' y2='856.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4280.4" y="863.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(300.5,4280.4,863.8)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.001" id="N64K_rsID_rs1199100713_1_293" sift="0.15">p.N64K</text>
<line x1='4771.2' y1='908.8' x2='4773.2' y2='906.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4773.2' y1='906.5' x2='4792.5' y2='883.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4792.5' y1='883.6' x2='4794.5' y2='881.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4808.1" y="891.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(310.3,4808.1,891.6)" sift="0.38" id="Q86R_rsID_rs746808776_1_46" polyphen2="0.017" class="mut" ipvMAF="NA" dbsource="dbSNP">p.Q86R</text>
<line x1='3675.1' y1='641.2' x2='3675.9' y2='638.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3675.9' y1='638.3' x2='3684.2' y2='609.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3684.2' y1='609.5' x2='3685.0' y2='606.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3701.6" y="610.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(286.0,3701.6,610.4)" sift="NA" id="K31K_rsID_rs758278442_1_114" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut">p.K31K</text>
<line x1='4181.2' y1='849.6' x2='4182.7' y2='846.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4182.7' y1='846.9' x2='4197.1' y2='820.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4197.1' y1='820.6' x2='4198.6' y2='818.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4213.9" y="825.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(298.8,4213.9,825.4)" id="Q60R_rsID_rs759162332_1_119" sift="0.24" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.014">p.Q60R</text>
<line x1='3500.5' y1='452.2' x2='3501.0' y2='449.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3501.0' y1='449.2' x2='3506.8' y2='419.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3506.8' y1='419.8' x2='3507.4' y2='416.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3524.3" y="419.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(281.1,3524.3,419.2)" polyphen2="NA" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="NA" id="T20T_rsID_rs372345059_1_31">p.T20T</text>
<line x1='2901.3' y1='390.4' x2='2901.2' y2='387.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2901.2' y1='387.4' x2='2900.1' y2='357.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2900.1' y1='357.4' x2='2900.0' y2='354.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2882.9" y="354.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(87.8,2882.9,354.1)" polyphen2="0.172" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0" id="F805I_rsID_rs749525058_1_53">p.F805I</text>
<line x1='3654.4' y1='328.5' x2='3655.1' y2='325.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3655.1' y1='325.6' x2='3662.2' y2='296.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3662.2' y1='296.4' x2='3662.9' y2='293.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3679.7" y="296.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(283.8,3679.7,296.6)" polyphen2="0.001" class="mut" ipvMAF="0.002119" dbsource="dbSNP" sift="0.41" id="K26R_rsID_rs4646116_1_68">p.K26R</text>
<line x1='1157.7' y1='4849.5' x2='1155.6' y2='4851.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1155.6' y1='4851.6' x2='1134.4' y2='4872.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='1134.4' y1='4872.9' x2='1132.3' y2='4875.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="1143.7" y="4887.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(-45.1,1143.7,4887.7)" id="F504I_rsID_rs760281053_1_121" sift="0" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.98">p.F504I</text>
<line x1='4097.5' y1='805.7' x2='4098.8' y2='803.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4098.8' y1='803.0' x2='4112.3' y2='776.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4112.3' y1='776.1' x2='4113.6' y2='773.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4128.8" y="780.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(296.6,4128.8,780.0)" polyphen2="0.555" dbsource="dbSNP" ipvMAF="NA" class="mut" sift="0" id="T55A_rsID_rs775273812_1_204">p.T55A</text>
<line x1='3602.1' y1='621.5' x2='3602.8' y2='618.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3602.8' y1='618.6' x2='3623.9' y2='593.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3623.9' y1='593.0' x2='3624.7' y2='590.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3641.3" y="593.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(284.5,3641.3,593.5)" polyphen2="0.003" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.78" id="T27A_rsID_rs781255386_1_227">p.T27A</text>
<line x1='3599.4' y1='468.5' x2='3600.1' y2='465.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3600.1' y1='465.6' x2='3607.0' y2='436.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3607.0' y1='436.4' x2='3607.7' y2='433.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3624.5" y="436.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(283.3,3624.5,436.5)" polyphen2="0.825" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.02" id="A25T_rsID_rs1434130600_1_412">p.A25T</text>
<line x1='4279.4' y1='906.5' x2='4281.0' y2='903.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4281.0' y1='903.9' x2='4296.6' y2='878.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4296.6' y1='878.3' x2='4298.2' y2='875.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4313.2" y="883.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(301.4,4313.2,883.8)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="G66G_rsID_rs370473130_1_22">p.G66G</text>
<line x1='4359.1' y1='957.3' x2='4360.8' y2='954.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4360.8' y1='954.8' x2='4377.4' y2='929.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4377.4' y1='929.9' x2='4379.1' y2='927.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4393.7" y="936.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(303.6,4393.7,936.0)" id="A71A_rsID_rs752154414_1_65" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.A71A</text>
<line x1='4556.7' y1='1103.6' x2='4558.6' y2='1101.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4558.6' y1='1101.3' x2='4577.6' y2='1078.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4577.6' y1='1078.1' x2='4579.5' y2='1075.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4593.2" y="1085.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(309.4,4593.2,1085.8)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.109" id="P84T_rsID_rs759134032_1_118" sift="0.14">p.P84T</text>
<line x1='3565.3' y1='612.5' x2='3566.0' y2='609.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3566.0' y1='609.6' x2='3572.9' y2='580.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3572.9' y1='580.4' x2='3573.6' y2='577.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3590.4" y="580.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(283.3,3590.4,580.5)" sift="NA" id="A25A_rsID_rs761614932_1_134" polyphen2="NA" ipvMAF="0.000265" dbsource="dbSNP" class="mut">p.A25A</text>
<line x1='3765.5' y1='669.0' x2='3766.4' y2='666.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3766.4' y1='666.1' x2='3789.3' y2='642.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3789.3' y1='642.1' x2='3790.2' y2='639.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3806.6" y="643.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(288.5,3806.6,643.7)" id="A36A_rsID_rs768558803_1_164" sift="NA" ipvMAF="0.00053" dbsource="dbSNP" class="mut" polyphen2="NA">p.A36A</text>
<line x1='923.5' y1='1693.2' x2='920.9' y2='1691.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='920.9' y1='1691.6' x2='903.1' y2='1663.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='903.1' y1='1663.7' x2='900.6' y2='1662.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="890.7" y="1675.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(203,24,29);" transform="rotate(32.5,890.7,1675.9)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.125" id="I679L_rsID_rs771673051_1_179" sift="0">p.I679L</text>
<line x1='3793.8' y1='518.4' x2='3794.7' y2='515.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3794.7' y1='515.5' x2='3803.9' y2='486.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3803.9' y1='486.9' x2='3804.8' y2='484.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3821.3" y="488.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(287.7,3821.3,488.4)" sift="0.48" id="E35D_rsID_rs778500138_1_214" polyphen2="0.015" dbsource="dbSNP" ipvMAF="NA" class="mut">p.E35D</text>
<line x1='3342.4' y1='570.5' x2='3342.8' y2='567.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3342.8' y1='567.5' x2='3347.0' y2='537.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3347.0' y1='537.8' x2='3347.4' y2='534.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3364.3" y="536.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(278.0,3364.3,536.3)" sift="NA" id="A13A_rsID_rs779538833_1_220" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.A13A</text>
<line x1='4471.9' y1='672.9' x2='4473.5' y2='670.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4473.5' y1='670.4' x2='4489.5' y2='645.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4489.5' y1='645.0' x2='4491.1' y2='642.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4506.0" y="650.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(302.3,4506.0,650.8)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.015" id="K68E_rsID_rs755691167_1_77" sift="0.65">p.K68E</text>
<line x1='3557.5' y1='472.3' x2='3558.2' y2='469.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3558.2' y1='469.3' x2='3564.6' y2='440.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3564.6' y1='440.0' x2='3565.3' y2='437.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3582.1" y="439.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(282.4,3582.1,439.8)" id="E23K_rsID_rs756231991_1_78" sift="0.32" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.159">p.E23K</text>
<line x1='3830.7' y1='534.7' x2='3831.7' y2='531.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3831.7' y1='531.8' x2='3841.2' y2='503.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3841.2' y1='503.4' x2='3842.2' y2='500.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3858.6" y="505.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(288.6,3858.6,505.1)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.523" id="E37K_rsID_rs146676783_1_105" sift="0.04">p.E37K</text>
<line x1='3654.4' y1='328.5' x2='3655.1' y2='325.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3655.1' y1='325.6' x2='3626.9' y2='288.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3626.9' y1='288.0' x2='3627.6' y2='285.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3644.3" y="288.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(283.0,3644.3,288.0)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.003" id="K26E_rsID_rs1299103394_1_340" sift="0.17">p.K26E</text>
<line x1='3838.9' y1='377.4' x2='3839.8' y2='374.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3839.8' y1='374.5' x2='3849.0' y2='346.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3849.0' y1='346.0' x2='3849.9' y2='343.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3866.3" y="347.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(287.7,3866.3,347.4)" polyphen2="0.013" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.72" id="E35K_rsID_rs1348114695_1_367">p.E35K</text>
<line x1='4421.5' y1='1000.2' x2='4423.2' y2='997.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4423.2' y1='997.8' x2='4440.6' y2='973.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4440.6' y1='973.3' x2='4442.3' y2='970.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4456.7" y="980.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(305.4,4456.7,980.0)" sift="0.05" id="E75G_rsID_rs867318181_1_230" polyphen2="0.386" ipvMAF="NA" dbsource="dbSNP" class="mut">p.E75G</text>
<line x1='4153.9' y1='503.3' x2='4155.2' y2='500.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4155.2' y1='500.5' x2='4167.8' y2='473.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4167.8' y1='473.3' x2='4169.0' y2='470.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4184.9" y="476.9" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(294.8,4184.9,476.9)" sift="0.06" id="N51S_rsID_rs1569243690_1_444" polyphen2="0.48" class="mut" ipvMAF="NA" dbsource="dbSNP">p.N51S</text>
<line x1='4012.1' y1='765.0' x2='4013.4' y2='762.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4013.4' y1='762.3' x2='4025.7' y2='734.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4025.7' y1='734.9' x2='4027.0' y2='732.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4042.8" y="738.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(294.4,4042.8,738.4)" id="Y50F_rsID_rs1192192618_1_291" sift="0.02" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.337">p.Y50F</text>
<line x1='4457.8' y1='845.3' x2='4459.4' y2='842.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4459.4' y1='842.8' x2='4476.3' y2='818.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4476.3' y1='818.0' x2='4477.9' y2='815.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4492.5" y="824.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(304.1,4492.5,824.2)" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.771" id="F72V_rsID_rs1256007252_1_323" sift="0.01">p.F72V</text>
<line x1='3417.1' y1='582.2' x2='3417.6' y2='579.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3417.6' y1='579.3' x2='3422.7' y2='549.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3422.7' y1='549.7' x2='3423.2' y2='546.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3440.1" y="548.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(279.8,3440.1,548.7)" id="A17S_rsID_rs1238916402_1_314" sift="0.08" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.622">p.A17S</text>
<line x1='3890.1' y1='713.7' x2='3891.2' y2='710.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3891.2' y1='710.9' x2='3902.1' y2='682.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3902.1' y1='682.9' x2='3903.2' y2='680.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3919.3" y="685.4" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(291.3,3919.3,685.4)" sift="0.3" id="S43R_rsID_rs1447927937_1_420" polyphen2="0.898" dbsource="dbSNP" ipvMAF="NA" class="mut">p.S43R</text>
<line x1='3363.0' y1='424.0' x2='3363.4' y2='421.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3363.4' y1='421.0' x2='3367.6' y2='391.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3367.6' y1='391.3' x2='3368.0' y2='388.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3385.0" y="389.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(278.0,3385.0,389.7)" id="A13S_rsID_rs1482922566_1_441" sift="0.15" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.582">p.A13S</text>
<line x1='3454.3' y1='588.9' x2='3454.9' y2='586.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3454.9' y1='586.0' x2='3460.4' y2='556.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3460.4' y1='556.5' x2='3461.0' y2='553.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3477.9" y="555.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(280.7,3477.9,555.8)" id="S19P_rsID_rs73635825_1_83" sift="0.19" class="mut" ipvMAF="0.000795" dbsource="dbSNP" polyphen2="0.74">p.S19P</text>
<line x1='4527.2' y1='1079.8' x2='4529.1' y2='1077.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4529.1' y1='1077.4' x2='4547.8' y2='1054.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4547.8' y1='1054.0' x2='4549.7' y2='1051.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4563.5" y="1061.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(308.5,4563.5,1061.5)" polyphen2="0.001" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.21" id="M82I_rsID_rs766996587_1_159">p.M82I</text>
<line x1='4616.3' y1='967.9' x2='4618.1' y2='965.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4618.1' y1='965.5' x2='4636.8' y2='942.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4636.8' y1='942.1' x2='4638.7' y2='939.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4652.6" y="949.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(308.5,4652.6,949.5)" sift="0.21" id="M82I_rsID_rs766996587_2_159" polyphen2="0.001" dbsource="dbSNP" ipvMAF="NA" class="mut">p.M82I</text>
<line x1='4629.1' y1='781.4' x2='4630.9' y2='778.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4630.9' y1='778.9' x2='4648.6' y2='754.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4648.6' y1='754.8' x2='4650.4' y2='752.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4664.7" y="761.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(306.3,4664.7,761.6)" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.952" id="S77F_rsID_rs1234981462_1_311" sift="0.15">p.S77F</text>
<line x1='5217.2' y1='4050.5' x2='5220.0' y2='4051.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5220.0' y1='4051.8' x2='5247.1' y2='4064.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='5247.1' y1='4064.6' x2='5249.8' y2='4065.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="5243.4" y="4081.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(25.4,5243.4,4081.6)" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA" sift="NA" id="I256I_rsID_rs377035576_1_38">p.I256I</text>
<line x1='2482.0' y1='440.4' x2='2481.4' y2='437.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2481.4' y1='437.4' x2='2475.5' y2='408.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2475.5' y1='408.0' x2='2474.9' y2='405.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2458.0" y="407.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(78.6,2458.0,407.5)" sift="NA" id="I784I_rsID_rs760076142_1_135" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut">p.I784I</text>
<line x1='2454.2' y1='303.2' x2='2453.6' y2='300.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2453.6' y1='300.2' x2='2447.7' y2='270.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2447.7' y1='270.8' x2='2447.1' y2='267.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2430.2" y="270.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(78.6,2430.2,270.3)" polyphen2="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="NA" id="I784I_rsID_rs760076142_2_135">p.I784I</text>
<line x1='3961.0' y1='586.8' x2='3962.1' y2='584.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3962.1' y1='584.0' x2='3973.2' y2='556.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3973.2' y1='556.1' x2='3974.3' y2='553.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3990.4" y="558.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(291.7,3990.4,558.8)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA" id="S44S_rsID_rs763637942_1_151" sift="NA">p.S44S</text>
<line x1='3884.4' y1='563.0' x2='3885.4' y2='560.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3885.4' y1='560.2' x2='3895.7' y2='532.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3895.7' y1='532.0' x2='3896.7' y2='529.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3913.0" y="534.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(289.9,3913.0,534.1)" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="0.005" id="F40L_rsID_rs924799658_1_244" sift="0.65">p.F40L</text>
<line x1='3932.2' y1='431.4' x2='3933.2' y2='428.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3933.2' y1='428.6' x2='3943.4' y2='400.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3943.4' y1='400.4' x2='3944.5' y2='397.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3960.8" y="402.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(289.9,3960.8,402.5)" id="F40L_rsID_rs924799658_2_244" sift="0.65" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.005">p.F40L</text>
<line x1='2912.5' y1='5451.9' x2='2912.4' y2='5454.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2912.4' y1='5454.9' x2='2897.1' y2='5484.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='2897.1' y1='5484.4' x2='2897.0' y2='5487.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="2913.9" y="5489.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:end;fill:rgb(35,139,69);" transform="rotate(-87.6,2913.9,5489.0)" polyphen2="NA" ipvMAF="NA" dbsource="dbSNP" class="mut" sift="NA" id="I407I_rsID_rs1459623504_1_428">p.I407I</text>
<line x1='3819.2' y1='687.3' x2='3820.2' y2='684.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3820.2' y1='684.5' x2='3830.2' y2='656.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3830.2' y1='656.2' x2='3831.2' y2='653.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3847.5" y="658.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(289.5,3847.5,658.2)" polyphen2="NA" dbsource="dbSNP" ipvMAF="0.000265" class="mut" sift="NA" id="L39L_rsID_rs199804629_1_4">p.L39L</text>
<line x1='4666.0' y1='1002.0' x2='4667.9' y2='999.7' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4667.9' y1='999.7' x2='4687.2' y2='976.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4687.2' y1='976.6' x2='4689.1' y2='974.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4702.7" y="984.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(309.8,4702.7,984.5)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="NA" id="L85L_rsID_rs376392863_1_37" sift="NA">p.L85L</text>
<line x1='4670.6' y1='1203.1' x2='4672.6' y2='1200.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4672.6' y1='1200.9' x2='4693.1' y2='1178.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='4693.1' y1='1178.9' x2='4695.1' y2='1176.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="4708.2" y="1187.6" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(312.9,4708.2,1187.6)" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.007" id="T92I_rsID_rs763395248_1_142" sift="0.24">p.T92I</text>
<line x1='3549.9' y1='310.1' x2='3550.5' y2='307.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3550.5' y1='307.2' x2='3556.5' y2='277.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3556.5' y1='277.8' x2='3557.1' y2='274.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3574.0" y="277.3" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(281.6,3574.0,277.3)" id="I21T_rsID_rs1244687367_1_316" sift="1" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0.003">p.I21T</text>
<line x1='3491.4' y1='596.2' x2='3492.0' y2='593.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3492.0' y1='593.3' x2='3513.9' y2='567.2' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3513.9' y1='567.2' x2='3514.5' y2='564.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3531.4" y="566.8" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(281.9,3531.4,566.8)" id="I21V_rsID_rs778030746_1_222" sift="0.84" dbsource="dbSNP" ipvMAF="NA" class="mut" polyphen2="0">p.I21V</text>
<line x1='3170.0' y1='300.8' x2='3170.2' y2='297.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3170.2' y1='297.9' x2='3172.1' y2='267.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3172.1' y1='267.9' x2='3172.3' y2='264.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3189.3" y="265.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(273.6,3189.3,265.0)" polyphen2="0.006" class="mut" ipvMAF="NA" dbsource="dbSNP" sift="0.01" id="S3N_rsID_rs1180242786_1_287">p.S3N</text>
<line x1='3142.3' y1='425.4' x2='3142.4' y2='422.4' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3142.4' y1='422.4' x2='3144.1' y2='392.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3144.1' y1='392.5' x2='3144.2' y2='389.5' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3161.3" y="389.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(273.2,3161.3,389.5)" id="S2P_rsID_rs760347219_1_123" sift="0.03" class="mut" dbsource="dbSNP" ipvMAF="NA" polyphen2="0.003">p.S2P</text>
<line x1='3280.7' y1='438.8' x2='3281.0' y2='435.9' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3281.0' y1='435.9' x2='3284.3' y2='406.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3284.3' y1='406.0' x2='3284.6' y2='403.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3301.6" y="404.0" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(276.3,3301.6,404.0)" id="L9P_rsID_rs746202722_1_43" sift="0.01" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.459">p.L9P</text>
<line x1='3116.5' y1='549.3' x2='3116.6' y2='546.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3116.6' y1='546.3' x2='3118.0' y2='516.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3118.0' y1='516.3' x2='3118.2' y2='513.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3135.2" y="513.2" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(272.7,3135.2,513.2)" id="M1I_rsID_rs768110251_1_162" sift="0.01" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.541">p.M1I</text>
<line x1='3248.5' y1='559.1' x2='3248.8' y2='556.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3248.8' y1='556.1' x2='3251.8' y2='526.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3251.8' y1='526.3' x2='3252.1' y2='523.3' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3269.1" y="524.1" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(203,24,29);" transform="rotate(275.8,3269.1,524.1)" id="L8F_rsID_rs201035388_1_11" sift="0.27" ipvMAF="NA" dbsource="dbSNP" class="mut" polyphen2="0.003">p.L8F</text>
<line x1='3192.0' y1='554.0' x2='3192.2' y2='551.0' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3192.2' y1='551.0' x2='3194.6' y2='521.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3194.6' y1='521.1' x2='3194.8' y2='518.1' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3211.8" y="518.5" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(274.5,3211.8,518.5)" id="S5S_rsID_rs775089013_1_195" sift="NA" class="mut" ipvMAF="NA" dbsource="dbSNP" polyphen2="NA">p.S5S</text>
<line x1='3294.3' y1='314.6' x2='3294.6' y2='311.6' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3294.6' y1='311.6' x2='3297.9' y2='281.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<line x1='3297.9' y1='281.8' x2='3298.2' y2='278.8' style="stroke-width:4.0;stroke:rgb(203,24,29);stroke-linecap:round;fill:none;" />
<text x="3315.2" y="279.7" font-size="36.4px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:start;fill:rgb(35,139,69);" transform="rotate(276.3,3315.2,279.7)" sift="NA" id="L9L_rsID_rs1463669655_1_431" polyphen2="NA" class="mut" dbsource="dbSNP" ipvMAF="NA">p.L9L</text>
</g>
<g id="plot4">
<g id="plot4-axis">
</g>
<line x1='3370.5' y1='4667.0' x2='3380.3' y2='4710.9' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3380.3' y1='4710.9' x2='3407.4' y2='4760.4' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3407.4' y1='4760.4' x2='3416.4' y2='4776.4' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3416.4' y1='4776.4' x2='3422.6' y2='4802.7' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3357.7' y1='4669.8' x2='3367.1' y2='4713.8' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3367.1' y1='4713.8' x2='3393.8' y2='4763.5' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3393.8' y1='4763.5' x2='3402.7' y2='4779.6' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3402.7' y1='4779.6' x2='3408.7' y2='4805.9' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3370.5' y1='4667.0' x2='3380.3' y2='4710.9' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3380.3' y1='4710.9' x2='3376.6' y2='4767.2' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3376.6' y1='4767.2' x2='3375.3' y2='4785.6' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3375.3' y1='4785.6' x2='3380.8' y2='4811.9' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3357.7' y1='4669.8' x2='3367.1' y2='4713.8' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3367.1' y1='4713.8' x2='3363.0' y2='4770.1' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3363.0' y1='4770.1' x2='3361.5' y2='4788.4' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3361.5' y1='4788.4' x2='3366.8' y2='4814.8' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='3319.0' y1='4677.7' x2='3327.3' y2='4721.8' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3327.3' y1='4721.8' x2='3353.0' y2='4772.1' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3353.0' y1='4772.1' x2='3361.5' y2='4788.4' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3361.5' y1='4788.4' x2='3366.8' y2='4814.8' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3319.0' y1='4677.7' x2='3327.3' y2='4721.8' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3327.3' y1='4721.8' x2='3322.0' y2='4778.0' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3322.0' y1='4778.0' x2='3320.0' y2='4796.3' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3320.0' y1='4796.3' x2='3324.8' y2='4822.8' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3004.9' y1='4707.7' x2='3005.0' y2='4752.7' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3005.0' y1='4752.7' x2='3020.9' y2='4806.8' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3020.9' y1='4806.8' x2='3026.3' y2='4824.4' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3026.3' y1='4824.4' x2='3026.7' y2='4851.3' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3004.9' y1='4707.7' x2='3005.0' y2='4752.7' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='3005.0' y1='4752.7' x2='2989.4' y2='4806.9' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='2989.4' y1='4806.9' x2='2984.1' y2='4824.5' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='2984.1' y1='4824.5' x2='2983.9' y2='4851.5' style="stroke-width:8.0;stroke:rgb(198,219,239);stroke-linecap:round;fill:none;" />
<line x1='1785.5' y1='4200.6' x2='1753.6' y2='4232.2' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1753.6' y1='4232.2' x2='1726.1' y2='4281.5' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1726.1' y1='4281.5' x2='1717.4' y2='4297.6' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1717.4' y1='4297.6' x2='1698.4' y2='4316.8' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1785.5' y1='4200.6' x2='1753.6' y2='4232.2' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1753.6' y1='4232.2' x2='1703.9' y2='4259.1' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1703.9' y1='4259.1' x2='1687.7' y2='4267.6' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
<line x1='1687.7' y1='4267.6' x2='1668.3' y2='4286.4' style="stroke-width:8.0;stroke:rgb(251,106,74);stroke-linecap:round;fill:none;" />
</g>
<g id="plot5">
<g id="plot5-axis">
</g>
<text x="3361.5" y="4687.6" font-size="58.5px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(251,106,74);" transform="rotate(-12.1,3361.5,4687.6)" id="Connector_374-376" class="connector">Active Site</text>
<text x="1817.5" y="4169.0" font-size="58.5px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(251,106,74);" transform="rotate(45.3,1817.5,4169.0)" id="Connector_504-506" class="connector">Active Site</text>
<text x="3360.4" y="4621.3" font-size="58.5px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(198,219,239);" transform="rotate(-12.5,3360.4,4621.3)" id="Connector_373-375" class="connector">Zn</text>
<text x="3306.2" y="4632.4" font-size="58.5px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(198,219,239);" transform="rotate(-10.6,3306.2,4632.4)" class="connector" id="Connector_377-379">Zn</text>
<text x="3004.8" y="4660.8" font-size="58.5px" font-family="CMUSansSerif-DemiCondensed" style="text-anchor:middle;fill:rgb(198,219,239);" transform="rotate(-0.2,3004.8,4660.8)" class="connector" id="Connector_401-403">Zn</text>
</g>
<g id="plot6">
<g id="plot6-axis">
</g>
<path d="M3055.074,1738.589 A1262.613,1262.613 40.000 0,1 3059.936,1738.811 L3062.309,1688.867 A1312.613,1312.613 0.000 0,0 3057.255,1688.637 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1132_3_1_substitution_" tilersid="rs768110251" class="tile" dbsource="dbSNP"/>
<path d="M3063.022,1673.884 A1327.613,1327.613 40.000 0,1 3073.242,1674.409 L3076.001,1624.486 A1377.613,1377.613 0.000 0,0 3065.395,1623.941 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs760347219" id="tile952_4_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3069.656,1739.310 A1262.613,1262.613 40.000 0,1 3079.373,1739.885 L3082.516,1689.984 A1312.613,1312.613 0.000 0,0 3072.415,1689.387 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1180242786" id="tile3235_8_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3089.084,1740.534 A1262.613,1262.613 40.000 0,1 3098.791,1741.258 L3102.703,1691.412 A1312.613,1312.613 0.000 0,0 3092.612,1690.659 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1314_15_1_substitution_" tilersid="rs775089013" class="tile" dbsource="dbSNP"/>
<path d="M3118.185,1742.931 A1262.613,1262.613 40.000 0,1 3127.872,1743.879 L3132.936,1694.136 A1312.613,1312.613 0.000 0,0 3122.865,1693.150 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs201035388" id="tile164_22_1_substitution_"/>
<path d="M3134.455,1679.214 A1327.613,1327.613 40.000 0,1 3144.632,1680.289 L3150.079,1630.587 A1377.613,1377.613 0.000 0,0 3139.519,1629.471 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile347_26_1_substitution_" tilersid="rs746202722" class="tile" dbsource="dbSNP"/>
<path d="M3121.289,1808.545 A1197.613,1197.613 40.000 0,1 3130.470,1809.516 L3135.917,1759.813 A1247.613,1247.613 0.000 0,0 3126.353,1758.802 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1463669655" id="tile5616_27_1_substitution_"/>
<path d="M3166.538,1748.419 A1262.613,1262.613 40.000 0,1 3176.181,1749.740 L3183.158,1700.229 A1312.613,1312.613 0.000 0,0 3173.133,1698.856 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs779538833" id="tile1434_39_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3175.111,1683.987 A1327.613,1327.613 40.000 0,1 3185.251,1685.376 L3192.228,1635.865 A1377.613,1377.613 0.000 0,0 3181.706,1634.424 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5789_37_1_substitution_" tilersid="rs1482922566"/>
<path d="M3205.045,1754.148 A1262.613,1262.613 40.000 0,1 3214.643,1755.766 L3223.143,1706.494 A1312.613,1312.613 0.000 0,0 3213.165,1704.812 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3711_49_1_substitution_" tilersid="rs1238916402" class="tile" dbsource="dbSNP"/>
<path d="M3224.229,1757.457 A1262.613,1262.613 40.000 0,1 3233.800,1759.223 L3243.059,1710.088 A1312.613,1312.613 0.000 0,0 3233.108,1708.252 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile769_55_1_substitution_" tilersid="rs73635825" class="tile" dbsource="dbSNP"/>
<path d="M3245.836,1695.347 A1327.613,1327.613 40.000 0,1 3255.886,1697.281 L3265.524,1648.218 A1377.613,1377.613 0.000 0,0 3255.095,1646.212 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile243_60_1_substitution_" tilersid="rs372345059"/>
<path d="M3243.358,1761.062 A1262.613,1262.613 40.000 0,1 3252.902,1762.975 L3262.917,1713.988 A1312.613,1312.613 0.000 0,0 3252.995,1712.000 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs778030746" id="tile1442_61_1_substitution_"/>
<path d="M3230.830,1824.843 A1197.613,1197.613 40.000 0,1 3239.882,1826.658 L3249.897,1777.671 A1247.613,1247.613 0.000 0,0 3240.467,1775.781 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1244687367" id="tile3757_62_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3262.430,1764.961 A1262.613,1262.613 40.000 0,1 3271.943,1767.021 L3282.712,1718.194 A1312.613,1312.613 0.000 0,0 3272.822,1716.053 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile705_67_1_substitution_" tilersid="rs756231991" class="tile" dbsource="dbSNP"/>
<path d="M3281.440,1769.154 A1262.613,1262.613 40.000 0,1 3290.920,1771.360 L3302.440,1722.705 A1312.613,1312.613 0.000 0,0 3292.585,1720.412 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs761614932" id="tile993_75_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3295.928,1705.789 A1327.613,1327.613 40.000 0,1 3305.896,1708.109 L3317.417,1659.454 A1377.613,1377.613 0.000 0,0 3307.073,1657.047 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5361_73_1_substitution_" tilersid="rs1434130600"/>
<path d="M3275.943,1834.611 A1197.613,1197.613 40.000 0,1 3284.918,1836.773 L3296.814,1788.208 A1247.613,1247.613 0.000 0,0 3287.463,1785.956 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile547_77_1_substitution_" tilersid="rs4646116" class="tile" dbsource="dbSNP"/>
<path d="M3320.873,1644.858 A1392.613,1392.613 40.000 0,1 3331.310,1647.372 L3343.205,1598.807 A1442.613,1442.613 0.000 0,0 3332.393,1596.203 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4245_76_1_substitution_" tilersid="rs1299103394" class="tile" dbsource="dbSNP"/>
<path d="M3300.382,1773.639 A1262.613,1262.613 40.000 0,1 3309.827,1775.991 L3322.096,1727.520 A1312.613,1312.613 0.000 0,0 3312.277,1725.075 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs781255386" id="tile1487_79_1_substitution_"/>
<path d="M3338.049,1783.483 A1262.613,1262.613 40.000 0,1 3347.416,1786.125 L3361.174,1738.055 A1312.613,1312.613 0.000 0,0 3351.436,1735.308 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile914_93_1_substitution_" tilersid="rs758278442" class="tile" dbsource="dbSNP"/>
<path d="M3366.090,1791.626 A1262.613,1262.613 40.000 0,1 3375.394,1794.484 L3390.259,1746.745 A1312.613,1312.613 0.000 0,0 3380.587,1743.773 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs368655410" id="tile209_102_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3394.719,1732.423 A1327.613,1327.613 40.000 0,1 3404.479,1735.503 L3419.712,1687.880 A1377.613,1377.613 0.000 0,0 3409.585,1684.684 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1386_105_1_substitution_" tilersid="rs778500138"/>
<path d="M3356.068,1856.544 A1197.613,1197.613 40.000 0,1 3364.872,1859.323 L3380.106,1811.700 A1247.613,1247.613 0.000 0,0 3370.934,1808.805 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4654_103_1_substitution_" tilersid="rs1348114695"/>
<path d="M3384.676,1797.413 A1262.613,1262.613 40.000 0,1 3393.935,1800.414 L3409.535,1752.910 A1312.613,1312.613 0.000 0,0 3399.909,1749.790 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs768558803" id="tile1156_108_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3414.215,1738.659 A1327.613,1327.613 40.000 0,1 3423.926,1741.890 L3439.891,1694.507 A1377.613,1377.613 0.000 0,0 3429.815,1691.155 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs146676783" id="tile836_109_1_substitution_"/>
<path d="M3412.382,1806.630 A1262.613,1262.613 40.000 0,1 3421.569,1809.845 L3438.263,1762.714 A1312.613,1312.613 0.000 0,0 3428.712,1759.372 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs199804629" id="tile144_117_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3443.272,1748.575 A1327.613,1327.613 40.000 0,1 3452.905,1752.029 L3469.963,1705.028 A1377.613,1377.613 0.000 0,0 3459.966,1701.444 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs924799658" id="tile1868_120_1_substitution_"/>
<path d="M3448.978,1819.911 A1262.613,1262.613 40.000 0,1 3458.062,1823.408 L3476.201,1776.814 A1312.613,1312.613 0.000 0,0 3466.758,1773.179 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1447927937" id="tile5486_129_1_substitution_"/>
<path d="M3481.643,1762.836 A1327.613,1327.613 40.000 0,1 3491.166,1766.586 L3509.664,1720.133 A1377.613,1377.613 0.000 0,0 3499.782,1716.242 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1071_132_1_substitution_" tilersid="rs763637942" class="tile" dbsource="dbSNP"/>
<path d="M3511.973,1845.845 A1262.613,1262.613 40.000 0,1 3520.855,1849.826 L3541.481,1804.279 A1312.613,1312.613 0.000 0,0 3532.248,1800.140 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1192192618" id="tile3340_149_1_substitution_"/>
<path d="M3547.669,1790.614 A1327.613,1327.613 40.000 0,1 3556.976,1794.872 L3577.952,1749.485 A1377.613,1377.613 0.000 0,0 3568.295,1745.067 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1000_151_1_substitution_" tilersid="rs760159085"/>
<path d="M3494.041,1909.038 A1197.613,1197.613 40.000 0,1 3502.437,1912.879 L3523.413,1867.491 A1247.613,1247.613 0.000 0,0 3514.667,1863.490 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1569243690" id="tile5929_152_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3556.068,1866.431 A1262.613,1262.613 40.000 0,1 3564.790,1870.751 L3587.156,1826.033 A1312.613,1312.613 0.000 0,0 3578.089,1821.541 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1345_163_1_substitution_" tilersid="rs775273812" class="tile" dbsource="dbSNP"/>
<path d="M3582.133,1879.593 A1262.613,1262.613 40.000 0,1 3590.752,1884.114 L3614.146,1839.924 A1312.613,1312.613 0.000 0,0 3605.185,1835.224 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1245_174_1_substitution_" tilersid="rs771621249" class="tile" dbsource="dbSNP"/>
<path d="M3612.101,1821.914 A1327.613,1327.613 40.000 0,1 3621.164,1826.667 L3644.559,1782.478 A1377.613,1377.613 0.000 0,0 3635.154,1777.545 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3578_172_1_substitution_" tilersid="rs1222417695"/>
<path d="M3599.337,1888.701 A1262.613,1262.613 40.000 0,1 3607.886,1893.354 L3631.958,1849.530 A1312.613,1312.613 0.000 0,0 3623.071,1844.693 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile934_179_1_substitution_" tilersid="rs759162332"/>
<path d="M3630.191,1831.491 A1327.613,1327.613 40.000 0,1 3639.180,1836.383 L3663.253,1792.560 A1377.613,1377.613 0.000 0,0 3653.925,1787.483 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1322_180_1_substitution_" tilersid="rs774593309"/>
<path d="M3616.398,1898.073 A1262.613,1262.613 40.000 0,1 3624.875,1902.857 L3649.620,1859.410 A1312.613,1312.613 0.000 0,0 3640.808,1854.436 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1325542104" id="tile4473_184_1_substitution_"/>
<path d="M3633.314,1907.707 A1262.613,1262.613 40.000 0,1 3641.715,1912.621 L3667.127,1869.561 A1312.613,1312.613 0.000 0,0 3658.393,1864.452 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1199100713" id="tile3350_192_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3650.078,1917.601 A1262.613,1262.613 40.000 0,1 3658.403,1922.644 L3684.476,1879.980 A1312.613,1312.613 0.000 0,0 3675.822,1874.737 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs370473130" id="tile225_198_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3692.298,1867.181 A1327.613,1327.613 40.000 0,1 3701.010,1872.552 L3727.411,1830.090 A1377.613,1377.613 0.000 0,0 3718.371,1824.517 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1254567742" id="tile3881_201_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3666.689,1927.752 A1262.613,1262.613 40.000 0,1 3674.934,1932.923 L3701.662,1890.666 A1312.613,1312.613 0.000 0,0 3693.090,1885.290 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile696_202_1_substitution_" tilersid="rs755691167"/>
<path d="M3691.305,1943.455 A1262.613,1262.613 40.000 0,1 3699.430,1948.816 L3727.127,1907.188 A1312.613,1312.613 0.000 0,0 3718.681,1901.615 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile502_213_1_substitution_" tilersid="rs752154414"/>
<path d="M3735.437,1894.700 A1327.613,1327.613 40.000 0,1 3743.935,1900.402 L3771.953,1858.990 A1377.613,1377.613 0.000 0,0 3763.134,1853.073 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1256007252" id="tile3890_214_1_substitution_"/>
<path d="M3723.551,1965.271 A1262.613,1262.613 40.000 0,1 3731.506,1970.879 L3760.474,1930.125 A1312.613,1312.613 0.000 0,0 3752.204,1924.295 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs867318181" id="tile1504_224_1_substitution_"/>
<path d="M3769.164,1917.899 A1327.613,1327.613 40.000 0,1 3777.483,1923.861 L3806.764,1883.332 A1377.613,1377.613 0.000 0,0 3798.132,1877.146 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1388651717" id="tile4990_228_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3739.417,1976.549 A1262.613,1262.613 40.000 0,1 3747.285,1982.279 L3776.877,1941.977 A1312.613,1312.613 0.000 0,0 3768.698,1936.020 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3682_230_1_substitution_" tilersid="rs1234981462" class="tile" dbsource="dbSNP"/>
<path d="M3778.306,2005.802 A1262.613,1262.613 40.000 0,1 3785.947,2011.831 L3817.071,1972.699 A1312.613,1312.613 0.000 0,0 3809.128,1966.431 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1124_246_1_substitution_" tilersid="rs766996587" class="tile" dbsource="dbSNP"/>
<path d="M3793.541,2017.919 A1262.613,1262.613 40.000 0,1 3801.088,2024.066 L3832.812,1985.418 A1312.613,1312.613 0.000 0,0 3824.966,1979.029 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs759134032" id="tile933_250_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3842.329,1973.824 A1327.613,1327.613 40.000 0,1 3850.214,1980.348 L3882.235,1941.946 A1377.613,1377.613 0.000 0,0 3874.052,1935.177 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile286_253_1_substitution_" tilersid="rs376392863" class="tile" dbsource="dbSNP"/>
<path d="M3808.588,2030.270 A1262.613,1262.613 40.000 0,1 3816.039,2036.532 L3848.355,1998.378 A1312.613,1312.613 0.000 0,0 3840.608,1991.868 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile364_257_1_substitution_" tilersid="rs746808776"/>
<path d="M3852.560,2068.694 A1262.613,1262.613 40.000 0,1 3859.714,2075.293 L3893.759,2038.675 A1312.613,1312.613 0.000 0,0 3886.322,2031.813 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1040_275_1_substitution_" tilersid="rs763395248"/>
<path d="M3908.337,2123.009 A1262.613,1262.613 40.000 0,1 3915.071,2130.037 L3951.308,2095.586 A1312.613,1312.613 0.000 0,0 3944.308,2088.279 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4991_300_1_substitution_" tilersid="rs1390680136" class="tile" dbsource="dbSNP"/>
<path d="M3921.750,2137.117 A1262.613,1262.613 40.000 0,1 3928.374,2144.248 L3965.138,2110.360 A1312.613,1312.613 0.000 0,0 3958.252,2102.946 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1395878099" id="tile5034_305_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3976.167,2100.193 A1327.613,1327.613 40.000 0,1 3983.075,2107.745 L4020.099,2074.141 A1377.613,1377.613 0.000 0,0 4012.932,2066.305 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile812_307_1_substitution_" tilersid="rs143158922"/>
<path d="M3880.581,2188.303 A1197.613,1197.613 40.000 0,1 3886.812,2195.115 L3923.836,2161.511 A1247.613,1247.613 0.000 0,0 3917.345,2154.414 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4581_309_1_substitution_" tilersid="rs1338694035"/>
<path d="M3934.943,2151.430 A1262.613,1262.613 40.000 0,1 3941.457,2158.662 L3978.739,2125.345 A1312.613,1312.613 0.000 0,0 3971.968,2117.826 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile779_312_1_substitution_" tilersid="rs111420317" class="tile" dbsource="dbSNP"/>
<path d="M3947.915,2165.945 A1262.613,1262.613 40.000 0,1 3954.316,2173.277 L3992.108,2140.538 A1312.613,1312.613 0.000 0,0 3985.453,2132.916 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2849_317_1_substitution_" tilersid="rs1038445507"/>
<path d="M4003.445,2130.717 A1327.613,1327.613 40.000 0,1 4010.116,2138.478 L4048.159,2106.032 A1377.613,1377.613 0.000 0,0 4041.236,2097.978 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile796_320_1_substitution_" tilersid="rs139773121"/>
<path d="M4003.454,2233.665 A1262.613,1262.613 40.000 0,1 4009.332,2241.423 L4049.302,2211.383 A1312.613,1312.613 0.000 0,0 4043.191,2203.317 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile188_344_1_substitution_" tilersid="rs201900069"/>
<path d="M4055.113,2194.213 A1327.613,1327.613 40.000 0,1 4061.293,2202.371 L4101.263,2172.331 A1377.613,1377.613 0.000 0,0 4094.850,2163.866 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4198_343_1_substitution_" tilersid="rs1292756480"/>
<path d="M3957.371,2280.475 A1197.613,1197.613 40.000 0,1 3962.889,2287.876 L4003.090,2258.145 A1247.613,1247.613 0.000 0,0 3997.341,2250.435 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1209189779" id="tile3467_346_1_substitution_"/>
<path d="M4113.254,2163.319 A1392.613,1392.613 40.000 0,1 4119.671,2171.926 L4159.871,2142.195 A1442.613,1442.613 0.000 0,0 4153.224,2133.279 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1340886951" id="tile4605_347_1_substitution_"/>
<path d="M4020.907,2257.074 A1262.613,1262.613 40.000 0,1 4026.604,2264.966 L4067.258,2235.858 A1312.613,1312.613 0.000 0,0 4061.335,2227.654 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile647_354_1_substitution_" tilersid="rs754488878" class="tile" dbsource="dbSNP"/>
<path d="M4069.953,2329.635 A1262.613,1262.613 40.000 0,1 4075.089,2337.902 L4117.663,2311.683 A1312.613,1312.613 0.000 0,0 4112.324,2303.088 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1398027862" id="tile5068_381_1_substitution_"/>
<path d="M4130.436,2303.817 A1327.613,1327.613 40.000 0,1 4135.769,2312.552 L4178.544,2286.662 A1377.613,1377.613 0.000 0,0 4173.010,2277.598 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile506_383_1_substitution_" tilersid="rs751227277" class="tile" dbsource="dbSNP"/>
<path d="M4122.886,2422.664 A1262.613,1262.613 40.000 0,1 4127.303,2431.337 L4171.945,2408.818 A1312.613,1312.613 0.000 0,0 4167.353,2399.801 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1102_412_1_substitution_" tilersid="rs766124365"/>
<path d="M4180.693,2392.942 A1327.613,1327.613 40.000 0,1 4185.337,2402.062 L4229.979,2379.542 A1377.613,1377.613 0.000 0,0 4225.160,2370.079 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1457896076" id="tile5558_414_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4069.269,2460.612 A1197.613,1197.613 40.000 0,1 4073.395,2468.871 L4118.209,2446.696 A1247.613,1247.613 0.000 0,0 4113.911,2438.093 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs370485974" id="tile226_417_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4135.936,2448.784 A1262.613,1262.613 40.000 0,1 4140.152,2457.557 L4185.302,2436.076 A1312.613,1312.613 0.000 0,0 4180.920,2426.956 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3035_423_1_substitution_" tilersid="rs1157386586" class="tile" dbsource="dbSNP"/>
<path d="M4194.415,2420.407 A1327.613,1327.613 40.000 0,1 4198.847,2429.632 L4243.998,2408.151 A1377.613,1377.613 0.000 0,0 4239.399,2398.579 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1391451327" id="tile4995_422_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4152.391,2484.068 A1262.613,1262.613 40.000 0,1 4156.334,2492.966 L4202.125,2472.888 A1312.613,1312.613 0.000 0,0 4198.026,2463.636 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1469916451" id="tile5692_435_1_substitution_"/>
<path d="M4167.749,2519.842 A1262.613,1262.613 40.000 0,1 4171.416,2528.858 L4217.805,2510.200 A1312.613,1312.613 0.000 0,0 4213.993,2500.827 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs373252182" id="tile240_446_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4185.385,2565.197 A1262.613,1262.613 40.000 0,1 4188.701,2574.348 L4235.774,2557.492 A1312.613,1312.613 0.000 0,0 4232.326,2547.979 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1435872603" id="tile5389_462_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4198.226,2601.950 A1262.613,1262.613 40.000 0,1 4201.259,2611.198 L4248.830,2595.802 A1312.613,1312.613 0.000 0,0 4245.677,2586.187 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs984704647" id="tile2383_472_1_substitution_"/>
<path d="M4263.101,2591.183 A1327.613,1327.613 40.000 0,1 4266.215,2600.932 L4313.902,2585.902 A1377.613,1377.613 0.000 0,0 4310.671,2575.786 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile338_476_1_substitution_" tilersid="rs746034076" class="tile" dbsource="dbSNP"/>
<path d="M4212.675,2648.419 A1262.613,1262.613 40.000 0,1 4215.349,2657.777 L4263.478,2644.225 A1312.613,1312.613 0.000 0,0 4260.698,2634.496 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs777568369" id="tile1371_487_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4277.916,2640.159 A1327.613,1327.613 40.000 0,1 4280.652,2650.021 L4328.884,2636.841 A1377.613,1377.613 0.000 0,0 4326.045,2626.607 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1303797112" id="tile4284_491_1_substitution_"/>
<path d="M4152.782,2675.395 A1197.613,1197.613 40.000 0,1 4155.250,2684.291 L4203.482,2671.110 A1247.613,1247.613 0.000 0,0 4200.911,2661.843 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1316799731" id="tile4405_490_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4220.481,2676.555 A1262.613,1262.613 40.000 0,1 4222.938,2685.973 L4271.367,2673.537 A1312.613,1312.613 0.000 0,0 4268.812,2663.746 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1177_496_1_substitution_" tilersid="rs769593006" class="tile" dbsource="dbSNP"/>
<path d="M4283.312,2659.904 A1327.613,1327.613 40.000 0,1 4285.896,2669.807 L4334.324,2657.371 A1377.613,1377.613 0.000 0,0 4331.644,2647.095 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs954282708" id="tile2128_497_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4157.650,2693.206 A1197.613,1197.613 40.000 0,1 4159.980,2702.139 L4208.409,2689.704 A1247.613,1247.613 0.000 0,0 4205.981,2680.398 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1391829986" id="tile5003_498_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4227.634,2704.864 A1262.613,1262.613 40.000 0,1 4229.873,2714.337 L4278.576,2703.024 A1312.613,1312.613 0.000 0,0 4276.249,2693.177 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3102_507_1_substitution_" tilersid="rs1165363168"/>
<path d="M4232.038,2723.826 A1262.613,1262.613 40.000 0,1 4234.131,2733.332 L4283.003,2722.772 A1312.613,1312.613 0.000 0,0 4280.828,2712.889 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile394_512_1_substitution_" tilersid="rs748076875"/>
<path d="M4295.464,2709.608 A1327.613,1327.613 40.000 0,1 4297.664,2719.604 L4346.536,2709.043 A1377.613,1377.613 0.000 0,0 4344.254,2698.672 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1341206593" id="tile4610_513_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4170.597,2747.060 A1197.613,1197.613 40.000 0,1 4172.512,2756.091 L4221.464,2745.908 A1247.613,1247.613 0.000 0,0 4219.469,2736.500 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1485_516_1_substitution_" tilersid="rs781175759"/>
<path d="M4236.150,2742.853 A1262.613,1262.613 40.000 0,1 4238.095,2752.390 L4287.124,2742.585 A1312.613,1312.613 0.000 0,0 4285.102,2732.670 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs751083544" id="tile454_519_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4299.787,2729.615 A1327.613,1327.613 40.000 0,1 4301.833,2739.643 L4350.862,2729.838 A1377.613,1377.613 0.000 0,0 4348.739,2719.432 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile653_517_1_substitution_" tilersid="rs754511501"/>
<path d="M4363.425,2716.377 A1392.613,1392.613 40.000 0,1 4365.571,2726.896 L4414.600,2717.091 A1442.613,1442.613 0.000 0,0 4412.377,2706.194 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1493_518_1_substitution_" tilersid="rs865852627" class="tile" dbsource="dbSNP"/>
<path d="M4245.141,2790.679 A1262.613,1262.613 40.000 0,1 4246.717,2800.284 L4296.088,2792.375 A1312.613,1312.613 0.000 0,0 4294.449,2782.390 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1437_533_1_substitution_" tilersid="rs779651019" class="tile" dbsource="dbSNP"/>
<path d="M4310.899,2790.002 A1327.613,1327.613 40.000 0,1 4312.479,2800.114 L4361.909,2792.586 A1377.613,1377.613 0.000 0,0 4360.269,2782.093 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1192307729" id="tile3341_537_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4253.487,2848.474 A1262.613,1262.613 40.000 0,1 4254.618,2858.141 L4304.301,2852.523 A1312.613,1312.613 0.000 0,0 4303.126,2842.473 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs758142853" id="tile910_551_1_substitution_"/>
<path d="M4255.674,2867.817 A1262.613,1262.613 40.000 0,1 4256.656,2877.500 L4306.420,2872.649 A1312.613,1312.613 0.000 0,0 4305.400,2862.582 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile445_557_1_substitution_" tilersid="rs750052167"/>
<path d="M4259.153,2906.593 A1262.613,1262.613 40.000 0,1 4259.835,2916.302 L4309.725,2912.988 A1312.613,1312.613 0.000 0,0 4309.016,2902.894 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2325_569_1_substitution_" tilersid="rs976723413" class="tile" dbsource="dbSNP"/>
<path d="M4324.692,2911.993 A1327.613,1327.613 40.000 0,1 4325.331,2922.208 L4375.245,2919.278 A1377.613,1377.613 0.000 0,0 4374.582,2908.679 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs765733397" id="tile1095_571_1_substitution_"/>
<path d="M4194.978,2920.611 A1197.613,1197.613 40.000 0,1 4195.555,2929.825 L4245.469,2926.895 A1247.613,1247.613 0.000 0,0 4244.868,2917.296 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1234885259" id="tile3680_573_1_substitution_"/>
<path d="M4260.976,2935.735 A1262.613,1262.613 40.000 0,1 4261.434,2945.457 L4311.387,2943.297 A1312.613,1312.613 0.000 0,0 4310.911,2933.190 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs762219565" id="tile1020_578_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4261.817,2955.183 A1262.613,1262.613 40.000 0,1 4262.125,2964.911 L4312.106,2963.522 A1312.613,1312.613 0.000 0,0 4311.785,2953.408 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1064_583_1_substitution_" tilersid="rs764661406" class="tile" dbsource="dbSNP"/>
<path d="M4327.100,2963.105 A1327.613,1327.613 40.000 0,1 4327.345,2973.337 L4377.335,2972.332 A1377.613,1377.613 0.000 0,0 4377.080,2961.716 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5201_588_1_substitution_" tilersid="rs1416468883" class="tile" dbsource="dbSNP"/>
<path d="M4262.358,2974.642 A1262.613,1262.613 40.000 0,1 4262.516,2984.374 L4312.512,2983.755 A1312.613,1312.613 0.000 0,0 4312.348,2973.638 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1214041216" id="tile3512_591_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4197.371,2975.947 A1197.613,1197.613 40.000 0,1 4197.521,2985.178 L4247.517,2984.560 A1247.613,1247.613 0.000 0,0 4247.361,2974.943 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4001_590_1_substitution_" tilersid="rs1271221183"/>
<path d="M4327.511,2983.569 A1327.613,1327.613 40.000 0,1 4327.598,2993.803 L4377.597,2993.570 A1377.613,1377.613 0.000 0,0 4377.507,2982.951 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1345857521" id="tile4656_592_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4262.599,2994.107 A1262.613,1262.613 40.000 0,1 4262.607,3003.840 L4312.606,3003.992 A1312.613,1312.613 0.000 0,0 4312.598,2993.873 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs750145841" id="tile451_596_1_substitution_"/>
<path d="M4197.599,2994.410 A1197.613,1197.613 40.000 0,1 4197.607,3003.642 L4247.607,3003.794 A1247.613,1247.613 0.000 0,0 4247.599,2994.177 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1277079227" id="tile4054_595_1_substitution_"/>
<path d="M4327.606,3004.038 A1327.613,1327.613 40.000 0,1 4327.536,3014.272 L4377.533,3014.809 A1377.613,1377.613 0.000 0,0 4377.606,3004.190 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1039062494" id="tile2871_600_1_substitution_"/>
<path d="M4261.888,3042.765 A1262.613,1262.613 40.000 0,1 4261.521,3052.491 L4311.478,3054.570 A1312.613,1312.613 0.000 0,0 4311.859,3044.459 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs779790336" id="tile1431_611_1_substitution_"/>
<path d="M4261.079,3062.215 A1262.613,1262.613 40.000 0,1 4260.562,3071.934 L4310.480,3074.783 A1312.613,1312.613 0.000 0,0 4311.018,3064.678 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile805_617_1_substitution_" tilersid="rs142443432"/>
<path d="M4325.456,3075.637 A1327.613,1327.613 40.000 0,1 4324.834,3085.853 L4374.729,3089.086 A1377.613,1377.613 0.000 0,0 4375.375,3078.486 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile633_620_1_substitution_" tilersid="rs754237613"/>
<path d="M4259.303,3091.360 A1262.613,1262.613 40.000 0,1 4258.561,3101.065 L4308.401,3105.067 A1312.613,1312.613 0.000 0,0 4309.172,3094.978 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4499_625_1_substitution_" tilersid="rs1327824339" class="tile" dbsource="dbSNP"/>
<path d="M4257.745,3110.764 A1262.613,1262.613 40.000 0,1 4256.853,3120.456 L4306.625,3125.226 A1312.613,1312.613 0.000 0,0 4307.552,3115.150 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile838_631_1_substitution_" tilersid="rs148771870" class="tile" dbsource="dbSNP"/>
<path d="M4252.542,3159.148 A1262.613,1262.613 40.000 0,1 4251.278,3168.799 L4300.829,3175.483 A1312.613,1312.613 0.000 0,0 4302.144,3165.450 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile666_648_1_substitution_" tilersid="rs753164828"/>
<path d="M4317.024,3167.341 A1327.613,1327.613 40.000 0,1 4315.695,3177.489 L4365.246,3184.173 A1377.613,1377.613 0.000 0,0 4366.625,3173.643 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile978_646_1_substitution_" tilersid="rs761269389" class="tile" dbsource="dbSNP"/>
<path d="M4186.862,3160.109 A1197.613,1197.613 40.000 0,1 4185.592,3169.253 L4235.090,3176.320 A1247.613,1247.613 0.000 0,0 4236.413,3166.794 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1300152093" id="tile4261_650_1_substitution_"/>
<path d="M4248.527,3188.070 A1262.613,1262.613 40.000 0,1 4247.040,3197.689 L4296.424,3205.517 A1312.613,1312.613 0.000 0,0 4297.969,3195.517 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile253_655_1_substitution_" tilersid="rs372272603" class="tile" dbsource="dbSNP"/>
<path d="M4312.802,3197.752 A1327.613,1327.613 40.000 0,1 4311.239,3207.866 L4360.622,3215.695 A1377.613,1377.613 0.000 0,0 4362.244,3205.199 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile959_656_1_substitution_" tilersid="rs759590772" class="tile" dbsource="dbSNP"/>
<path d="M4184.252,3178.388 A1197.613,1197.613 40.000 0,1 4182.842,3187.512 L4232.225,3195.340 A1247.613,1247.613 0.000 0,0 4233.694,3185.836 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5076_657_1_substitution_" tilersid="rs1399442625"/>
<path d="M4375.437,3218.043 A1392.613,1392.613 40.000 0,1 4373.715,3228.640 L4423.037,3236.849 A1442.613,1442.613 0.000 0,0 4424.820,3225.872 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1323_658_1_substitution_" tilersid="rs774621083"/>
<path d="M4243.844,3216.891 A1262.613,1262.613 40.000 0,1 4242.135,3226.473 L4291.324,3235.442 A1312.613,1312.613 0.000 0,0 4293.101,3225.480 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1479566186" id="tile5763_664_1_substitution_"/>
<path d="M4306.081,3238.132 A1327.613,1327.613 40.000 0,1 4304.207,3248.193 L4353.325,3257.541 A1377.613,1377.613 0.000 0,0 4355.270,3247.101 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4624_667_1_substitution_" tilersid="rs1342472374" class="tile" dbsource="dbSNP"/>
<path d="M4232.486,3274.170 A1262.613,1262.613 40.000 0,1 4230.336,3283.663 L4279.057,3294.896 A1312.613,1312.613 0.000 0,0 4281.293,3285.027 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1231367923" id="tile3752_684_1_substitution_"/>
<path d="M4293.674,3298.266 A1327.613,1327.613 40.000 0,1 4291.336,3308.230 L4339.970,3319.838 A1377.613,1377.613 0.000 0,0 4342.396,3309.499 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1204132218" id="tile3422_686_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4223.447,3312.038 A1262.613,1262.613 40.000 0,1 4221.005,3321.460 L4269.358,3334.190 A1312.613,1312.613 0.000 0,0 4271.896,3324.395 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1239_696_1_substitution_" tilersid="rs771188220" class="tile" dbsource="dbSNP"/>
<path d="M4283.863,3338.009 A1327.613,1327.613 40.000 0,1 4281.220,3347.896 L4329.472,3360.998 A1377.613,1377.613 0.000 0,0 4332.216,3350.739 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1528_698_1_substitution_" tilersid="rs868538858" class="tile" dbsource="dbSNP"/>
<path d="M4215.904,3340.246 A1262.613,1262.613 40.000 0,1 4213.245,3349.609 L4261.290,3363.454 A1312.613,1312.613 0.000 0,0 4264.055,3353.720 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1172580854" id="tile3164_704_1_substitution_"/>
<path d="M4204.836,3377.571 A1262.613,1262.613 40.000 0,1 4201.890,3386.848 L4249.485,3402.167 A1312.613,1312.613 0.000 0,0 4252.548,3392.523 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1448326240" id="tile5494_717_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4195.783,3405.331 A1262.613,1262.613 40.000 0,1 4192.623,3414.537 L4239.851,3430.953 A1312.613,1312.613 0.000 0,0 4243.136,3421.383 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4745_725_1_substitution_" tilersid="rs1360329820"/>
<path d="M4182.718,3442.005 A1262.613,1262.613 40.000 0,1 4179.275,3451.109 L4225.975,3468.974 A1312.613,1312.613 0.000 0,0 4229.554,3459.509 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile315_738_1_substitution_" tilersid="rs563087491" class="tile" dbsource="dbSNP"/>
<path d="M4243.605,3464.760 A1327.613,1327.613 40.000 0,1 4239.985,3474.333 L4286.685,3492.197 A1377.613,1377.613 0.000 0,0 4290.441,3482.264 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs775542703" id="tile1339_736_1_substitution_"/>
<path d="M4164.807,3487.253 A1262.613,1262.613 40.000 0,1 4161.016,3496.217 L4206.993,3515.868 A1312.613,1312.613 0.000 0,0 4210.934,3506.548 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs886466413" id="tile1549_751_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4220.786,3521.763 A1327.613,1327.613 40.000 0,1 4216.728,3531.158 L4262.551,3551.162 A1377.613,1377.613 0.000 0,0 4266.763,3541.413 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs371464495" id="tile223_754_1_substitution_"/>
<path d="M4101.246,3470.672 A1197.613,1197.613 40.000 0,1 4097.585,3479.147 L4143.409,3499.151 A1247.613,1247.613 0.000 0,0 4147.223,3490.322 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1251_755_1_substitution_" tilersid="rs771769548"/>
<path d="M4145.166,3531.776 A1262.613,1262.613 40.000 0,1 4141.032,3540.588 L4186.218,3561.996 A1312.613,1312.613 0.000 0,0 4190.515,3552.835 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile289_768_1_substitution_" tilersid="rs377035576"/>
<path d="M4199.773,3568.418 A1327.613,1327.613 40.000 0,1 4195.356,3577.650 L4240.375,3599.405 A1377.613,1377.613 0.000 0,0 4244.959,3589.825 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs745514718" id="tile334_770_1_substitution_"/>
<path d="M4132.562,3558.115 A1262.613,1262.613 40.000 0,1 4128.226,3566.829 L4172.905,3589.276 A1312.613,1312.613 0.000 0,0 4177.412,3580.217 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3071_776_1_substitution_" tilersid="rs1161338919"/>
<path d="M4186.308,3596.010 A1327.613,1327.613 40.000 0,1 4181.678,3605.137 L4226.182,3627.928 A1377.613,1377.613 0.000 0,0 4230.986,3618.457 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs868599322" id="tile1529_778_1_substitution_"/>
<path d="M4123.823,3575.510 A1262.613,1262.613 40.000 0,1 4119.353,3584.156 L4163.680,3607.289 A1312.613,1312.613 0.000 0,0 4168.327,3598.300 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2940_783_1_substitution_" tilersid="rs1049125260"/>
<path d="M4114.817,3592.767 A1262.613,1262.613 40.000 0,1 4110.214,3601.344 L4154.179,3625.157 A1312.613,1312.613 0.000 0,0 4158.964,3616.241 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile171_787_1_substitution_" tilersid="rs200745906" class="tile" dbsource="dbSNP"/>
<path d="M4091.147,3635.286 A1262.613,1262.613 40.000 0,1 4086.217,3643.679 L4129.232,3669.169 A1312.613,1312.613 0.000 0,0 4134.357,3660.444 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1407010163" id="tile5123_802_1_substitution_"/>
<path d="M4142.136,3676.816 A1327.613,1327.613 40.000 0,1 4136.885,3685.600 L4179.702,3711.421 A1377.613,1377.613 0.000 0,0 4185.151,3702.306 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4799_807_1_substitution_" tilersid="rs1365337188" class="tile" dbsource="dbSNP"/>
<path d="M4081.223,3652.033 A1262.613,1262.613 40.000 0,1 4076.165,3660.348 L4118.781,3686.499 A1312.613,1312.613 0.000 0,0 4124.040,3677.854 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs766319182" id="tile1113_808_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4049.919,3701.328 A1262.613,1262.613 40.000 0,1 4044.481,3709.400 L4085.843,3737.493 A1312.613,1312.613 0.000 0,0 4091.496,3729.101 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1495_827_1_substitution_" tilersid="rs866821244" class="tile" dbsource="dbSNP"/>
<path d="M4027.798,3733.364 A1262.613,1262.613 40.000 0,1 4022.114,3741.265 L4062.590,3770.619 A1312.613,1312.613 0.000 0,0 4068.499,3762.405 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1451564530" id="tile5510_839_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4074.733,3779.426 A1327.613,1327.613 40.000 0,1 4068.692,3787.687 L4108.941,3817.353 A1377.613,1377.613 0.000 0,0 4115.209,3808.780 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs202032109" id="tile192_841_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4010.564,3756.935 A1262.613,1262.613 40.000 0,1 4004.699,3764.703 L4044.486,3794.985 A1312.613,1312.613 0.000 0,0 4050.583,3786.910 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1203006090" id="tile3413_847_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4056.422,3804.070 A1327.613,1327.613 40.000 0,1 4050.192,3812.190 L4089.744,3842.778 A1377.613,1377.613 0.000 0,0 4096.208,3834.352 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs267606408" id="tile184_850_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3952.977,3725.335 A1197.613,1197.613 40.000 0,1 3947.357,3732.660 L3986.909,3763.248 A1247.613,1247.613 0.000 0,0 3992.763,3755.618 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1344315438" id="tile4633_852_1_substitution_"/>
<path d="M3986.747,3787.731 A1262.613,1262.613 40.000 0,1 3980.645,3795.314 L4019.479,3826.809 A1312.613,1312.613 0.000 0,0 4025.823,3818.926 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1035_860_1_substitution_" tilersid="rs763264372" class="tile" dbsource="dbSNP"/>
<path d="M4037.545,3828.284 A1327.613,1327.613 40.000 0,1 4031.130,3836.258 L4069.963,3867.752 A1377.613,1377.613 0.000 0,0 4076.621,3859.479 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1165212018" id="tile3100_859_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3974.485,3802.850 A1262.613,1262.613 40.000 0,1 3968.267,3810.339 L4006.611,3842.428 A1312.613,1312.613 0.000 0,0 4013.075,3834.644 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs773273611" id="tile1273_867_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M4018.114,3852.055 A1327.613,1327.613 40.000 0,1 4011.516,3859.878 L4049.611,3892.263 A1377.613,1377.613 0.000 0,0 4056.458,3884.145 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1046_868_1_substitution_" tilersid="rs763994205"/>
<path d="M3961.992,3817.779 A1262.613,1262.613 40.000 0,1 3955.659,3825.170 L3993.504,3857.847 A1312.613,1312.613 0.000 0,0 4000.087,3850.163 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile707_872_1_substitution_" tilersid="rs756358940"/>
<path d="M4004.857,3867.650 A1327.613,1327.613 40.000 0,1 3998.139,3875.371 L4035.730,3908.339 A1377.613,1377.613 0.000 0,0 4042.702,3900.327 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3807_874_1_substitution_" tilersid="rs1248745003" class="tile" dbsource="dbSNP"/>
<path d="M3936.322,3847.049 A1262.613,1262.613 40.000 0,1 3929.765,3854.241 L3966.584,3888.070 A1312.613,1312.613 0.000 0,0 3973.401,3880.592 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs776226831" id="tile1353_884_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3923.152,3861.383 A1262.613,1262.613 40.000 0,1 3916.484,3868.474 L3952.777,3902.866 A1312.613,1312.613 0.000 0,0 3959.709,3895.494 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs745744395" id="tile352_891_1_substitution_"/>
<path d="M3970.676,3905.728 A1327.613,1327.613 40.000 0,1 3963.665,3913.184 L3999.958,3947.575 A1377.613,1377.613 0.000 0,0 4007.233,3939.839 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1264_889_1_substitution_" tilersid="rs772143709" class="tile" dbsource="dbSNP"/>
<path d="M3869.303,3823.764 A1197.613,1197.613 40.000 0,1 3862.927,3830.441 L3898.954,3865.112 A1247.613,1247.613 0.000 0,0 3905.596,3858.156 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4766_893_1_substitution_" tilersid="rs1362308420"/>
<path d="M3902.986,3882.500 A1262.613,1262.613 40.000 0,1 3896.156,3889.435 L3931.644,3924.657 A1312.613,1312.613 0.000 0,0 3938.745,3917.448 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs773936807" id="tile1308_899_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3882.337,3903.145 A1262.613,1262.613 40.000 0,1 3875.349,3909.920 L3910.013,3945.953 A1312.613,1312.613 0.000 0,0 3917.278,3938.910 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile430_907_1_substitution_" tilersid="rs749750821"/>
<path d="M3846.879,3936.475 A1262.613,1262.613 40.000 0,1 3839.635,3942.976 L3872.885,3980.318 A1312.613,1312.613 0.000 0,0 3880.416,3973.560 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs766518362" id="tile1116_924_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3832.341,3949.420 A1262.613,1262.613 40.000 0,1 3824.997,3955.808 L3857.668,3993.659 A1312.613,1312.613 0.000 0,0 3865.302,3987.018 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile905_930_1_substitution_" tilersid="rs758382603" class="tile" dbsource="dbSNP"/>
<path d="M3867.469,4005.014 A1327.613,1327.613 40.000 0,1 3859.696,4011.671 L3892.073,4049.772 A1377.613,1377.613 0.000 0,0 3900.139,4042.864 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs373974232" id="tile247_933_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3817.605,3962.140 A1262.613,1262.613 40.000 0,1 3810.164,3968.414 L3842.246,4006.763 A1312.613,1312.613 0.000 0,0 3849.982,4000.241 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs780574871" id="tile1464_934_1_substitution_"/>
<path d="M3855.790,4014.977 A1327.613,1327.613 40.000 0,1 3840.040,4028.050 L3871.677,4066.768 A1377.613,1377.613 0.000 0,0 3888.020,4053.203 Z" style="stroke-linecap:round;fill:rgb(255,0,255);" tilersid="rs1490929895" id="tile5857_935_2_deletion_" dbsource="dbSNP" class="tile"/>
<path d="M3768.456,3918.559 A1197.613,1197.613 40.000 0,1 3761.352,3924.456 L3793.138,3963.052 A1247.613,1247.613 0.000 0,0 3800.539,3956.909 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1336_939_1_substitution_" tilersid="rs775440758" class="tile" dbsource="dbSNP"/>
<path d="M3787.553,3986.889 A1262.613,1262.613 40.000 0,1 3779.922,3992.931 L3810.807,4032.252 A1312.613,1312.613 0.000 0,0 3818.740,4025.971 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs767374564" id="tile1130_948_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3764.521,4004.837 A1262.613,1262.613 40.000 0,1 3756.752,4010.701 L3786.720,4050.725 A1312.613,1312.613 0.000 0,0 3794.796,4044.629 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1221192598" id="tile3571_957_1_substitution_"/>
<path d="M3709.212,4044.610 A1262.613,1262.613 40.000 0,1 3701.138,4050.046 L3728.903,4091.628 A1312.613,1312.613 0.000 0,0 3737.297,4085.977 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs759579097" id="tile958_977_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3684.866,4060.730 A1262.613,1262.613 40.000 0,1 3676.669,4065.978 L3703.465,4108.192 A1312.613,1312.613 0.000 0,0 3711.987,4102.736 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile822_986_1_substitution_" tilersid="rs143936283" class="tile" dbsource="dbSNP"/>
<path d="M3660.154,4076.284 A1262.613,1262.613 40.000 0,1 3651.838,4081.341 L3677.651,4124.162 A1312.613,1312.613 0.000 0,0 3686.296,4118.905 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile43_994_1_substitution_" tilersid="rs185525294"/>
<path d="M3685.395,4137.009 A1327.613,1327.613 40.000 0,1 3676.609,4142.259 L3702.091,4185.278 A1377.613,1377.613 0.000 0,0 3711.208,4179.830 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1372_997_1_substitution_" tilersid="rs777626602" class="tile" dbsource="dbSNP"/>
<path d="M3618.281,4025.673 A1197.613,1197.613 40.000 0,1 3610.356,4030.409 L3635.838,4073.428 A1247.613,1247.613 0.000 0,0 3644.094,4068.494 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1253786077" id="tile3870_999_1_substitution_"/>
<path d="M3643.482,4086.334 A1262.613,1262.613 40.000 0,1 3635.089,4091.262 L3660.239,4134.476 A1312.613,1312.613 0.000 0,0 3668.965,4129.353 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1306455142" id="tile4322_1002_1_substitution_"/>
<path d="M3709.736,4198.184 A1392.613,1392.613 40.000 0,1 3700.479,4203.619 L3725.628,4246.834 A1442.613,1442.613 0.000 0,0 3735.218,4241.203 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5694_1001_1_substitution_" tilersid="rs1471486893"/>
<path d="M3618.190,4100.923 A1262.613,1262.613 40.000 0,1 3609.684,4105.656 L3633.828,4149.440 A1312.613,1312.613 0.000 0,0 3642.670,4144.520 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs762357444" id="tile1022_1009_1_substitution_"/>
<path d="M3650.014,4157.599 A1327.613,1327.613 40.000 0,1 3641.071,4162.576 L3665.215,4206.360 A1377.613,1377.613 0.000 0,0 3674.495,4201.196 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs865959788" id="tile1533_1010_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3578.297,4048.736 A1197.613,1197.613 40.000 0,1 3570.196,4053.163 L3594.001,4097.132 A1247.613,1247.613 0.000 0,0 3602.441,4092.521 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1800_1013_1_substitution_" tilersid="rs916715573" class="tile" dbsource="dbSNP"/>
<path d="M3601.143,4110.323 A1262.613,1262.613 40.000 0,1 3592.566,4114.924 L3616.032,4159.076 A1312.613,1312.613 0.000 0,0 3624.949,4154.292 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1286_1016_1_substitution_" tilersid="rs772710779"/>
<path d="M3623.072,4172.321 A1327.613,1327.613 40.000 0,1 3614.016,4177.089 L3637.141,4221.420 A1377.613,1377.613 0.000 0,0 3646.537,4216.473 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1181373965" id="tile3249_1020_1_substitution_"/>
<path d="M3583.954,4119.459 A1262.613,1262.613 40.000 0,1 3575.307,4123.927 L3598.089,4168.435 A1312.613,1312.613 0.000 0,0 3607.078,4163.790 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile807_1022_1_substitution_" tilersid="rs138390800" class="tile" dbsource="dbSNP"/>
<path d="M3604.924,4181.788 A1327.613,1327.613 40.000 0,1 3595.796,4186.416 L3618.234,4231.098 A1377.613,1377.613 0.000 0,0 3627.706,4226.296 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2144_1026_1_substitution_" tilersid="rs956290521" class="tile" dbsource="dbSNP"/>
<path d="M3540.382,4141.130 A1262.613,1262.613 40.000 0,1 3531.569,4145.262 L3552.620,4190.615 A1312.613,1312.613 0.000 0,0 3561.781,4186.319 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1410274315" id="tile5162_1036_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3496.008,4161.106 A1262.613,1262.613 40.000 0,1 3487.042,4164.895 L3506.329,4211.025 A1312.613,1312.613 0.000 0,0 3515.650,4207.086 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs147464721" id="tile831_1051_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3521.542,4220.880 A1327.613,1327.613 40.000 0,1 3512.115,4224.864 L3531.402,4270.995 A1377.613,1377.613 0.000 0,0 3541.184,4266.861 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2828_1053_1_substitution_" tilersid="rs1035663418"/>
<path d="M3461.969,4104.926 A1197.613,1197.613 40.000 0,1 3453.438,4108.454 L3472.369,4154.732 A1247.613,1247.613 0.000 0,0 3481.256,4151.056 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs370610075" id="tile228_1055_1_substitution_"/>
<path d="M3469.025,4172.265 A1262.613,1262.613 40.000 0,1 3459.974,4175.846 L3478.190,4222.410 A1312.613,1312.613 0.000 0,0 3487.599,4218.687 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs200909433" id="tile161_1062_1_substitution_"/>
<path d="M3483.654,4236.379 A1327.613,1327.613 40.000 0,1 3474.109,4240.071 L3491.964,4286.774 A1377.613,1377.613 0.000 0,0 3501.869,4282.943 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2205_1063_1_substitution_" tilersid="rs961360700" class="tile" dbsource="dbSNP"/>
<path d="M3414.322,4192.698 A1262.613,1262.613 40.000 0,1 3405.115,4195.856 L3421.158,4243.213 A1312.613,1312.613 0.000 0,0 3430.729,4239.929 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3441_1078_1_substitution_" tilersid="rs1205410066" class="tile" dbsource="dbSNP"/>
<path d="M3358.733,4210.579 A1262.613,1262.613 40.000 0,1 3349.390,4213.308 L3363.226,4261.356 A1312.613,1312.613 0.000 0,0 3372.939,4258.518 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs758568640" id="tile931_1097_1_substitution_"/>
<path d="M3367.377,4275.770 A1327.613,1327.613 40.000 0,1 3357.531,4278.564 L3370.996,4326.717 A1377.613,1377.613 0.000 0,0 3381.213,4323.818 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs750477605" id="tile462_1101_1_substitution_"/>
<path d="M3340.026,4215.966 A1262.613,1262.613 40.000 0,1 3330.643,4218.551 L3343.736,4266.806 A1312.613,1312.613 0.000 0,0 3353.492,4264.118 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1228750646" id="tile3634_1102_1_substitution_"/>
<path d="M3321.239,4221.063 A1262.613,1262.613 40.000 0,1 3311.817,4223.503 L3324.165,4271.955 A1312.613,1312.613 0.000 0,0 3333.961,4269.418 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1407_1110_1_substitution_" tilersid="rs779083203" class="tile" dbsource="dbSNP"/>
<path d="M3302.376,4225.871 A1262.613,1262.613 40.000 0,1 3292.917,4228.165 L3304.517,4276.801 A1312.613,1312.613 0.000 0,0 3314.350,4274.416 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1304733999" id="tile4296_1116_1_substitution_"/>
<path d="M3283.441,4230.387 A1262.613,1262.613 40.000 0,1 3273.947,4232.535 L3284.796,4281.344 A1312.613,1312.613 0.000 0,0 3294.665,4279.111 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile888_1122_1_substitution_" tilersid="rs757578476"/>
<path d="M3298.032,4293.728 A1327.613,1327.613 40.000 0,1 3288.050,4295.987 L3298.899,4344.796 A1377.613,1377.613 0.000 0,0 3309.257,4342.452 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1309363592" id="tile4338_1121_1_substitution_"/>
<path d="M3259.845,4169.084 A1197.613,1197.613 40.000 0,1 3250.825,4171.052 L3261.296,4219.943 A1247.613,1247.613 0.000 0,0 3270.693,4217.893 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1395782023" id="tile5033_1125_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M3264.438,4234.610 A1262.613,1262.613 40.000 0,1 3254.913,4236.612 L3265.007,4285.583 A1312.613,1312.613 0.000 0,0 3274.910,4283.502 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile689_1127_1_substitution_" tilersid="rs754076967" class="tile" dbsource="dbSNP"/>
<path d="M3268.036,4300.274 A1327.613,1327.613 40.000 0,1 3258.004,4302.301 L3267.721,4351.348 A1377.613,1377.613 0.000 0,0 3278.131,4349.244 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs767462182" id="tile1131_1130_1_substitution_"/>
<path d="M3245.373,4238.541 A1262.613,1262.613 40.000 0,1 3235.818,4240.395 L3245.156,4289.515 A1312.613,1312.613 0.000 0,0 3255.089,4287.587 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs142984500" id="tile809_1133_1_substitution_"/>
<path d="M3197.464,4247.076 A1262.613,1262.613 40.000 0,1 3187.844,4248.561 L3195.283,4298.005 A1312.613,1312.613 0.000 0,0 3205.283,4296.461 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5056_1148_1_substitution_" tilersid="rs1396769231" class="tile" dbsource="dbSNP"/>
<path d="M3197.515,4312.838 A1327.613,1327.613 40.000 0,1 3187.388,4314.321 L3194.446,4363.821 A1377.613,1377.613 0.000 0,0 3204.953,4362.281 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile791_1152_1_substitution_" tilersid="rs138689466" class="tile" dbsource="dbSNP"/>
<path d="M3149.261,4253.759 A1262.613,1262.613 40.000 0,1 3139.592,4254.872 L3145.120,4304.566 A1312.613,1312.613 0.000 0,0 3155.172,4303.408 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile480_1163_1_substitution_" tilersid="rs751572714" class="tile" dbsource="dbSNP"/>
<path d="M3156.945,4318.303 A1327.613,1327.613 40.000 0,1 3146.778,4319.474 L3152.306,4369.167 A1377.613,1377.613 0.000 0,0 3162.856,4367.953 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs773676270" id="tile1292_1164_1_substitution_"/>
<path d="M3132.406,4190.271 A1197.613,1197.613 40.000 0,1 3123.226,4191.256 L3128.371,4240.991 A1247.613,1247.613 0.000 0,0 3137.934,4239.964 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1043_1166_1_substitution_" tilersid="rs762890235"/>
<path d="M3061.987,4261.090 A1262.613,1262.613 40.000 0,1 3052.263,4261.530 L3054.333,4311.488 A1312.613,1312.613 0.000 0,0 3064.441,4311.030 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1365935088" id="tile4793_1189_1_substitution_"/>
<path d="M3054.954,4326.475 A1327.613,1327.613 40.000 0,1 3044.727,4326.859 L3046.411,4376.830 A1377.613,1377.613 0.000 0,0 3057.024,4376.432 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs772619843" id="tile1278_1192_1_substitution_"/>
<path d="M3049.573,4196.586 A1197.613,1197.613 40.000 0,1 3040.347,4196.933 L3042.032,4246.904 A1247.613,1247.613 0.000 0,0 3051.643,4246.543 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4598_1194_1_substitution_" tilersid="rs1339365248"/>
<path d="M3032.808,4262.186 A1262.613,1262.613 40.000 0,1 3023.077,4262.402 L3023.991,4312.393 A1312.613,1312.613 0.000 0,0 3034.107,4312.169 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1214851578" id="tile3522_1198_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2984.146,4262.513 A1262.613,1262.613 40.000 0,1 2974.414,4262.353 L2973.401,4312.343 A1312.613,1312.613 0.000 0,0 2983.518,4312.509 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1418150776" id="tile5221_1214_1_substitution_"/>
<path d="M2978.213,4327.434 A1327.613,1327.613 40.000 0,1 2957.750,4326.940 L2956.159,4376.915 A1377.613,1377.613 0.000 0,0 2977.392,4377.427 Z" style="stroke-linecap:round;fill:rgb(255,0,255);" dbsource="dbSNP" class="tile" tilersid="rs746336281" id="tile349_1213_2_deletion_"/>
<path d="M2975.731,4197.367 A1197.613,1197.613 40.000 0,1 2966.502,4197.144 L2965.103,4247.124 A1247.613,1247.613 0.000 0,0 2974.718,4247.356 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1184887977" id="tile3282_1218_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2964.683,4262.118 A1262.613,1262.613 40.000 0,1 2954.955,4261.809 L2953.171,4311.777 A1312.613,1312.613 0.000 0,0 2963.285,4312.099 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5582_1221_1_substitution_" tilersid="rs1459623504"/>
<path d="M2886.964,4257.543 A1262.613,1262.613 40.000 0,1 2877.273,4256.634 L2872.413,4306.397 A1312.613,1312.613 0.000 0,0 2882.488,4307.342 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1193_1245_1_substitution_" tilersid="rs769251490"/>
<path d="M2857.914,4254.592 A1262.613,1262.613 40.000 0,1 2848.247,4253.460 L2842.238,4303.097 A1312.613,1312.613 0.000 0,0 2852.288,4304.275 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile163_1252_1_substitution_" tilersid="rs200995847" class="tile" dbsource="dbSNP"/>
<path d="M2850.600,4319.179 A1327.613,1327.613 40.000 0,1 2840.435,4317.989 L2834.426,4367.626 A1377.613,1377.613 0.000 0,0 2844.973,4368.862 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5653_1253_1_substitution_" tilersid="rs1466701781"/>
<path d="M2856.060,4188.931 A1197.613,1197.613 40.000 0,1 2846.899,4187.786 L2840.507,4237.376 A1247.613,1247.613 0.000 0,0 2850.050,4238.569 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1209307377" id="tile3469_1256_1_substitution_"/>
<path d="M2838.589,4252.253 A1262.613,1262.613 40.000 0,1 2828.941,4250.971 L2822.167,4300.510 A1312.613,1312.613 0.000 0,0 2832.197,4301.842 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1384237654" id="tile4946_1258_1_substitution_"/>
<path d="M2820.134,4315.372 A1327.613,1327.613 40.000 0,1 2810.000,4313.946 L2802.844,4363.432 A1377.613,1377.613 0.000 0,0 2813.360,4364.911 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4696_1262_1_substitution_" tilersid="rs1352508510"/>
<path d="M2819.302,4249.615 A1262.613,1262.613 40.000 0,1 2809.675,4248.185 L2802.138,4297.614 A1312.613,1312.613 0.000 0,0 2812.147,4299.101 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile988_1264_1_substitution_" tilersid="rs761489852"/>
<path d="M2804.937,4313.204 A1327.613,1327.613 40.000 0,1 2794.819,4311.661 L2787.092,4361.061 A1377.613,1377.613 0.000 0,0 2797.590,4362.662 Z" style="stroke-linecap:round;fill:rgb(255,0,255);" class="tile" dbsource="dbSNP" id="tile3905_1264_1_deletion_frameshift" tilersid="rs1258744122"/>
<path d="M2780.862,4243.450 A1262.613,1262.613 40.000 0,1 2771.283,4241.724 L2762.226,4290.897 A1312.613,1312.613 0.000 0,0 2772.184,4292.692 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3703_1276_1_substitution_" tilersid="rs1238146879"/>
<path d="M2769.581,4307.464 A1327.613,1327.613 40.000 0,1 2759.509,4305.649 L2750.451,4354.822 A1377.613,1377.613 0.000 0,0 2760.903,4356.705 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4568_1278_1_substitution_" tilersid="rs1335386721"/>
<path d="M2783.057,4177.799 A1197.613,1197.613 40.000 0,1 2773.985,4176.092 L2764.548,4225.194 A1247.613,1247.613 0.000 0,0 2774.000,4226.972 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1316056737" id="tile4404_1279_1_substitution_"/>
<path d="M2752.166,4238.050 A1262.613,1262.613 40.000 0,1 2742.630,4236.103 L2732.438,4285.053 A1312.613,1312.613 0.000 0,0 2742.352,4287.078 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5535_1285_1_substitution_" tilersid="rs1454617025" class="tile" dbsource="dbSNP"/>
<path d="M2729.380,4299.738 A1327.613,1327.613 40.000 0,1 2719.369,4297.614 L2708.800,4346.484 A1377.613,1377.613 0.000 0,0 2719.188,4348.689 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1448548701" id="tile5487_1290_1_substitution_"/>
<path d="M2704.643,4227.581 A1262.613,1262.613 40.000 0,1 2695.188,4225.267 L2683.118,4273.789 A1312.613,1312.613 0.000 0,0 2692.946,4276.193 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1829_1302_1_substitution_" tilersid="rs918930523" class="tile" dbsource="dbSNP"/>
<path d="M2676.335,4220.422 A1262.613,1262.613 40.000 0,1 2666.936,4217.891 L2653.747,4266.120 A1312.613,1312.613 0.000 0,0 2663.517,4268.752 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs199569050" id="tile138_1311_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2659.672,4283.250 A1327.613,1327.613 40.000 0,1 2649.790,4280.589 L2636.600,4328.818 A1377.613,1377.613 0.000 0,0 2646.855,4331.580 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4373_1309_1_substitution_" tilersid="rs1314469120"/>
<path d="M2657.558,4215.287 A1262.613,1262.613 40.000 0,1 2648.199,4212.612 L2634.268,4260.631 A1312.613,1312.613 0.000 0,0 2643.997,4263.413 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2221_1315_1_substitution_" tilersid="rs964898848"/>
<path d="M2630.089,4275.037 A1327.613,1327.613 40.000 0,1 2620.271,4272.148 L2605.969,4320.059 A1377.613,1377.613 0.000 0,0 2616.157,4323.057 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2679_1320_1_substitution_" tilersid="rs1017439564" class="tile" dbsource="dbSNP"/>
<path d="M2601.733,4198.154 A1262.613,1262.613 40.000 0,1 2592.509,4195.049 L2576.372,4242.373 A1312.613,1312.613 0.000 0,0 2585.962,4245.602 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile979_1335_1_substitution_" tilersid="rs761297461" class="tile" dbsource="dbSNP"/>
<path d="M2581.230,4259.836 A1327.613,1327.613 40.000 0,1 2571.531,4256.570 L2555.394,4303.895 A1377.613,1377.613 0.000 0,0 2565.459,4307.283 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs764772589" id="tile1058_1334_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2613.487,4133.527 A1197.613,1197.613 40.000 0,1 2604.760,4130.514 L2588.259,4177.712 A1247.613,1247.613 0.000 0,0 2597.350,4180.851 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4183_1338_1_substitution_" tilersid="rs1290769028" class="tile" dbsource="dbSNP"/>
<path d="M2583.309,4191.872 A1262.613,1262.613 40.000 0,1 2574.133,4188.624 L2557.269,4235.694 A1312.613,1312.613 0.000 0,0 2566.807,4239.071 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1356_1339_1_substitution_" tilersid="rs776328956"/>
<path d="M2552.209,4249.815 A1327.613,1327.613 40.000 0,1 2542.588,4246.326 L2525.361,4293.265 A1377.613,1377.613 0.000 0,0 2535.345,4296.885 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1073_1343_1_substitution_" tilersid="rs763655186" class="tile" dbsource="dbSNP"/>
<path d="M2596.057,4127.433 A1197.613,1197.613 40.000 0,1 2587.378,4124.286 L2570.151,4171.224 A1247.613,1247.613 0.000 0,0 2579.192,4174.503 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1201_1344_1_substitution_" tilersid="rs770297403"/>
<path d="M2555.859,4181.917 A1262.613,1262.613 40.000 0,1 2546.761,4178.458 L2528.812,4225.126 A1312.613,1312.613 0.000 0,0 2538.270,4228.722 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs760321012" id="tile951_1348_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2528.646,4171.331 A1262.613,1262.613 40.000 0,1 2519.631,4167.662 L2500.608,4213.902 A1312.613,1312.613 0.000 0,0 2509.980,4217.716 Z" style="stroke-linecap:round;fill:rgb(255,0,255);" id="tile736_1359_1_insertion_frameshift" tilersid="rs34998679" class="tile" dbsource="dbSNP"/>
<path d="M2494.901,4227.774 A1327.613,1327.613 40.000 0,1 2485.451,4223.844 L2466.073,4269.936 A1377.613,1377.613 0.000 0,0 2475.878,4274.014 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2592_1362_1_substitution_" tilersid="rs1009196459"/>
<path d="M2510.644,4163.925 A1262.613,1262.613 40.000 0,1 2501.686,4160.118 L2481.952,4206.059 A1312.613,1312.613 0.000 0,0 2491.265,4210.017 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs775744448" id="tile1332_1365_1_substitution_"/>
<path d="M2535.836,4104.005 A1197.613,1197.613 40.000 0,1 2527.339,4100.394 L2507.606,4146.335 A1247.613,1247.613 0.000 0,0 2516.457,4150.097 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3160_1364_1_substitution_" tilersid="rs1171652794"/>
<path d="M2474.992,4148.284 A1262.613,1262.613 40.000 0,1 2466.156,4144.203 L2445.015,4189.514 A1312.613,1312.613 0.000 0,0 2454.201,4193.757 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs11798104" id="tile724_1377_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2438.673,4203.107 A1327.613,1327.613 40.000 0,1 2429.415,4198.744 L2407.926,4243.891 A1377.613,1377.613 0.000 0,0 2417.533,4248.418 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2363_1380_1_substitution_" tilersid="rs981162998"/>
<path d="M2457.351,4140.054 A1262.613,1262.613 40.000 0,1 2448.579,4135.837 L2426.742,4180.816 A1312.613,1312.613 0.000 0,0 2435.862,4185.200 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1476137643" id="tile5735_1381_1_substitution_"/>
<path d="M2420.191,4194.310 A1327.613,1327.613 40.000 0,1 2411.002,4189.805 L2388.819,4234.615 A1377.613,1377.613 0.000 0,0 2398.355,4239.290 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1463563888" id="tile5612_1386_1_substitution_"/>
<path d="M2439.839,4131.552 A1262.613,1262.613 40.000 0,1 2431.133,4127.200 L2408.606,4171.838 A1312.613,1312.613 0.000 0,0 2417.657,4176.362 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs772445388" id="tile1256_1387_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2468.677,4073.299 A1197.613,1197.613 40.000 0,1 2460.419,4069.172 L2437.891,4113.809 A1247.613,1247.613 0.000 0,0 2446.494,4118.109 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1169303958" id="tile3129_1388_1_substitution_"/>
<path d="M2422.461,4122.782 A1262.613,1262.613 40.000 0,1 2413.823,4118.296 L2390.610,4162.581 A1312.613,1312.613 0.000 0,0 2399.590,4167.244 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile354_1395_1_substitution_" tilersid="rs746405119"/>
<path d="M2383.646,4175.867 A1327.613,1327.613 40.000 0,1 2374.600,4171.080 L2351.046,4215.185 A1377.613,1377.613 0.000 0,0 2360.433,4220.152 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs774978137" id="tile1311_1396_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2405.219,4113.744 A1262.613,1262.613 40.000 0,1 2396.651,4109.126 L2372.759,4153.048 A1312.613,1312.613 0.000 0,0 2381.666,4157.849 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3997_1399_1_substitution_" tilersid="rs1270795706" class="tile" dbsource="dbSNP"/>
<path d="M2365.591,4166.225 A1327.613,1327.613 40.000 0,1 2356.619,4161.299 L2332.389,4205.036 A1377.613,1377.613 0.000 0,0 2341.698,4210.146 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs191860450" id="tile119_1402_1_substitution_"/>
<path d="M2371.165,4094.877 A1262.613,1262.613 40.000 0,1 2362.743,4089.997 L2337.508,4133.162 A1312.613,1312.613 0.000 0,0 2346.263,4138.235 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile176_1413_1_substitution_" tilersid="rs200499668"/>
<path d="M2338.792,4151.242 A1327.613,1327.613 40.000 0,1 2329.937,4146.111 L2304.701,4189.275 A1377.613,1377.613 0.000 0,0 2313.890,4194.600 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile923_1411_1_substitution_" tilersid="rs759033741" class="tile" dbsource="dbSNP"/>
<path d="M2395.550,4033.884 A1197.613,1197.613 40.000 0,1 2387.598,4029.193 L2362.030,4072.162 A1247.613,1247.613 0.000 0,0 2370.314,4077.048 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4808_1415_1_substitution_" tilersid="rs1366555470" class="tile" dbsource="dbSNP"/>
<path d="M2296.777,4048.650 A1262.613,1262.613 40.000 0,1 2288.714,4043.198 L2260.546,4084.509 A1312.613,1312.613 0.000 0,0 2268.929,4090.177 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1382719890" id="tile4928_1438_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2252.096,4096.902 A1327.613,1327.613 40.000 0,1 2243.663,4091.104 L2215.178,4132.197 A1377.613,1377.613 0.000 0,0 2223.929,4138.213 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5183_1443_1_substitution_" tilersid="rs1411114707"/>
<path d="M2280.693,4037.684 A1262.613,1262.613 40.000 0,1 2272.715,4032.108 L2243.914,4072.980 A1312.613,1312.613 0.000 0,0 2252.208,4078.777 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs748359955" id="tile402_1445_1_substitution_"/>
<path d="M2235.274,4085.242 A1327.613,1327.613 40.000 0,1 2226.931,4079.314 L2197.816,4119.963 A1377.613,1377.613 0.000 0,0 2206.473,4126.113 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1429_1449_1_substitution_" tilersid="rs779752560"/>
<path d="M2249.043,4015.014 A1262.613,1262.613 40.000 0,1 2241.240,4009.195 L2211.193,4049.159 A1312.613,1312.613 0.000 0,0 2219.304,4055.209 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5781_1458_1_substitution_" tilersid="rs1480725606"/>
<path d="M2233.483,4003.316 A1262.613,1262.613 40.000 0,1 2225.772,3997.377 L2195.112,4036.874 A1312.613,1312.613 0.000 0,0 2203.129,4043.048 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile162_1463_1_substitution_" tilersid="rs200973492"/>
<path d="M2185.914,4048.723 A1327.613,1327.613 40.000 0,1 2177.854,4042.416 L2146.891,4081.675 A1377.613,1377.613 0.000 0,0 2155.254,4088.219 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2283_1465_1_substitution_" tilersid="rs962791083" class="tile" dbsource="dbSNP"/>
<path d="M2210.487,3985.322 A1262.613,1262.613 40.000 0,1 2202.915,3979.207 L2171.350,4017.984 A1312.613,1312.613 0.000 0,0 2179.222,4024.341 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs750415079" id="tile470_1471_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2161.881,4029.617 A1327.613,1327.613 40.000 0,1 2153.969,4023.125 L2122.106,4061.658 A1377.613,1377.613 0.000 0,0 2130.316,4068.394 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3567_1474_1_substitution_" tilersid="rs1221577570"/>
<path d="M2187.913,3966.802 A1262.613,1262.613 40.000 0,1 2180.485,3960.513 L2148.031,3998.550 A1312.613,1312.613 0.000 0,0 2155.754,4005.087 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs765152220" id="tile1078_1481_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2165.774,3947.764 A1262.613,1262.613 40.000 0,1 2158.492,3941.305 L2125.168,3978.581 A1312.613,1312.613 0.000 0,0 2132.738,3985.296 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2202_1489_1_substitution_" tilersid="rs961921482" class="tile" dbsource="dbSNP"/>
<path d="M2151.261,3934.790 A1262.613,1262.613 40.000 0,1 2144.080,3928.220 L2110.185,3964.978 A1312.613,1312.613 0.000 0,0 2117.651,3971.808 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3786_1497_1_substitution_" tilersid="rs1246309926" class="tile" dbsource="dbSNP"/>
<path d="M2100.017,3976.005 A1327.613,1327.613 40.000 0,1 2092.520,3969.038 L2058.343,4005.534 A1377.613,1377.613 0.000 0,0 2066.122,4012.763 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1205522386" id="tile3443_1500_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2136.950,3921.594 A1262.613,1262.613 40.000 0,1 2129.872,3914.914 L2095.414,3951.145 A1312.613,1312.613 0.000 0,0 2102.773,3958.089 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs368996871" id="tile212_1503_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2181.381,3874.150 A1197.613,1197.613 40.000 0,1 2174.666,3867.813 L2140.209,3904.044 A1247.613,1247.613 0.000 0,0 2147.203,3910.645 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile790_1501_1_substitution_" tilersid="rs140473595"/>
<path d="M2122.845,3908.179 A1262.613,1262.613 40.000 0,1 2115.870,3901.390 L2080.858,3937.085 A1312.613,1312.613 0.000 0,0 2088.109,3944.143 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile418_1509_1_substitution_" tilersid="rs748701949" class="tile" dbsource="dbSNP"/>
<path d="M2070.354,3947.794 A1327.613,1327.613 40.000 0,1 2063.075,3940.599 L2027.789,3976.024 A1377.613,1377.613 0.000 0,0 2035.342,3983.489 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile949_1510_1_substitution_" tilersid="rs760281053"/>
<path d="M2161.385,3854.986 A1197.613,1197.613 40.000 0,1 2154.819,3848.496 L2119.533,3883.920 A1247.613,1247.613 0.000 0,0 2126.373,3890.681 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1285805675" id="tile4131_1512_1_substitution_"/>
<path d="M2108.947,3894.548 A1262.613,1262.613 40.000 0,1 2102.078,3887.652 L2066.520,3922.804 A1312.613,1312.613 0.000 0,0 2073.661,3929.972 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2653_1514_1_substitution_" tilersid="rs1016409802"/>
<path d="M2055.852,3933.349 A1327.613,1327.613 40.000 0,1 2048.686,3926.043 L2012.858,3960.919 A1377.613,1377.613 0.000 0,0 2020.294,3968.500 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1344_1517_1_substitution_" tilersid="rs775181355"/>
<path d="M2088.500,3873.703 A1262.613,1262.613 40.000 0,1 2081.792,3866.651 L2045.430,3900.971 A1312.613,1312.613 0.000 0,0 2052.404,3908.302 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4669_1522_1_substitution_" tilersid="rs1349942475"/>
<path d="M2075.138,3859.547 A1262.613,1262.613 40.000 0,1 2068.540,3852.392 L2031.653,3886.147 A1312.613,1312.613 0.000 0,0 2038.513,3893.585 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs779199005" id="tile1425_1528_1_substitution_"/>
<path d="M2020.587,3896.273 A1327.613,1327.613 40.000 0,1 2013.707,3888.697 L1976.562,3922.166 A1377.613,1377.613 0.000 0,0 1983.701,3930.028 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5444_1533_1_substitution_" tilersid="rs1443937359" class="tile" dbsource="dbSNP"/>
<path d="M2049.078,3830.624 A1262.613,1262.613 40.000 0,1 2042.703,3823.269 L2004.793,3855.871 A1312.613,1312.613 0.000 0,0 2011.421,3863.517 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs868506911" id="tile1526_1541_1_substitution_"/>
<path d="M2000.123,3873.385 A1327.613,1327.613 40.000 0,1 1993.420,3865.652 L1955.511,3898.253 A1377.613,1377.613 0.000 0,0 1962.467,3906.278 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4705_1540_1_substitution_" tilersid="rs1352194082"/>
<path d="M2091.985,3780.887 A1197.613,1197.613 40.000 0,1 2085.992,3773.864 L2047.833,3806.173 A1247.613,1247.613 0.000 0,0 2054.075,3813.489 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3949_1544_1_substitution_" tilersid="rs1263424292" class="tile" dbsource="dbSNP"/>
<path d="M2030.124,3808.413 A1262.613,1262.613 40.000 0,1 2023.921,3800.912 L1985.268,3832.629 A1312.613,1312.613 0.000 0,0 1991.717,3840.426 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1406026054" id="tile5119_1551_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1973.672,3842.143 A1327.613,1327.613 40.000 0,1 1967.211,3834.207 L1928.314,3865.624 A1377.613,1377.613 0.000 0,0 1935.019,3873.860 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1158307424" id="tile3047_1553_1_substitution_"/>
<path d="M2017.776,3793.364 A1262.613,1262.613 40.000 0,1 2011.689,3785.769 L1972.552,3816.885 A1312.613,1312.613 0.000 0,0 1978.879,3824.781 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5458_1556_1_substitution_" tilersid="rs1445263977"/>
<path d="M2005.661,3778.127 A1262.613,1262.613 40.000 0,1 1999.693,3770.438 L1960.080,3800.948 A1312.613,1312.613 0.000 0,0 1966.285,3808.941 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs751987956" id="tile494_1563_1_substitution_"/>
<path d="M1954.472,3818.185 A1327.613,1327.613 40.000 0,1 1948.196,3810.101 L1908.584,3840.611 A1377.613,1377.613 0.000 0,0 1915.096,3848.999 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile935_1561_1_substitution_" tilersid="rs759200680" class="tile" dbsource="dbSNP"/>
<path d="M1993.783,3762.704 A1262.613,1262.613 40.000 0,1 1987.934,3754.925 L1947.855,3784.820 A1312.613,1312.613 0.000 0,0 1953.936,3792.908 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2676_1569_1_substitution_" tilersid="rs1019324840" class="tile" dbsource="dbSNP"/>
<path d="M1976.415,3739.232 A1262.613,1262.613 40.000 0,1 1970.747,3731.320 L1929.988,3760.280 A1312.613,1312.613 0.000 0,0 1935.881,3768.506 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3201_1578_1_substitution_" tilersid="rs1176549305" class="tile" dbsource="dbSNP"/>
<path d="M1965.140,3723.364 A1262.613,1262.613 40.000 0,1 1959.594,3715.365 L1918.394,3743.693 A1312.613,1312.613 0.000 0,0 1924.159,3752.009 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1120_1584_1_substitution_" tilersid="rs766808999"/>
<path d="M1906.034,3752.192 A1327.613,1327.613 40.000 0,1 1900.268,3743.737 L1858.850,3771.747 A1377.613,1377.613 0.000 0,0 1864.833,3780.521 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs956890785" id="tile2152_1585_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1943.330,3691.115 A1262.613,1262.613 40.000 0,1 1938.034,3682.948 L1895.980,3709.993 A1312.613,1312.613 0.000 0,0 1901.486,3718.483 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1070_1594_1_substitution_" tilersid="rs763593286" class="tile" dbsource="dbSNP"/>
<path d="M1932.801,3674.742 A1262.613,1262.613 40.000 0,1 1927.631,3666.495 L1885.165,3692.888 A1312.613,1312.613 0.000 0,0 1890.539,3701.462 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1294_1601_1_substitution_" tilersid="rs773746588"/>
<path d="M1912.506,3641.519 A1262.613,1262.613 40.000 0,1 1907.593,3633.116 L1864.333,3658.188 A1312.613,1312.613 0.000 0,0 1869.440,3666.923 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4385_1613_1_substitution_" tilersid="rs1315545082"/>
<path d="M1897.962,3616.199 A1262.613,1262.613 40.000 0,1 1893.244,3607.686 L1849.416,3631.750 A1312.613,1312.613 0.000 0,0 1854.320,3640.601 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1563_1622_1_substitution_" tilersid="rs889263894" class="tile" dbsource="dbSNP"/>
<path d="M1888.593,3599.136 A1262.613,1262.613 40.000 0,1 1884.007,3590.551 L1839.813,3613.937 A1312.613,1312.613 0.000 0,0 1844.580,3622.862 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3220_1629_1_substitution_" tilersid="rs1178831057"/>
<path d="M1826.555,3620.952 A1327.613,1327.613 40.000 0,1 1821.803,3611.888 L1777.430,3634.933 A1377.613,1377.613 0.000 0,0 1782.361,3644.339 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1208_1631_1_substitution_" tilersid="rs769821600" class="tile" dbsource="dbSNP"/>
<path d="M1875.035,3573.275 A1262.613,1262.613 40.000 0,1 1870.649,3564.586 L1825.927,3586.944 A1312.613,1312.613 0.000 0,0 1830.486,3595.977 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs756905974" id="tile876_1637_1_substitution_"/>
<path d="M1817.121,3602.788 A1327.613,1327.613 40.000 0,1 1812.510,3593.651 L1767.787,3616.009 A1377.613,1377.613 0.000 0,0 1772.572,3625.490 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs761944150" id="tile1028_1636_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1928.789,3535.521 A1197.613,1197.613 40.000 0,1 1924.693,3527.247 L1879.799,3549.260 A1247.613,1247.613 0.000 0,0 1884.066,3557.879 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs373025684" id="tile237_1640_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1853.780,3529.499 A1262.613,1262.613 40.000 0,1 1849.732,3520.647 L1804.181,3541.265 A1312.613,1312.613 0.000 0,0 1808.389,3550.468 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1543_1651_1_substitution_" tilersid="rs867060899"/>
<path d="M1790.516,3547.451 A1327.613,1327.613 40.000 0,1 1786.331,3538.111 L1740.623,3558.377 A1377.613,1377.613 0.000 0,0 1744.964,3568.069 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile782_1655_1_substitution_" tilersid="rs112493570" class="tile" dbsource="dbSNP"/>
<path d="M1845.753,3511.765 A1262.613,1262.613 40.000 0,1 1841.842,3502.852 L1795.978,3522.765 A1312.613,1312.613 0.000 0,0 1800.044,3532.031 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1667_1658_1_substitution_" tilersid="rs899455705"/>
<path d="M1838.000,3493.909 A1262.613,1262.613 40.000 0,1 1834.227,3484.937 L1788.062,3504.140 A1312.613,1312.613 0.000 0,0 1791.984,3513.468 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs961465783" id="tile2207_1665_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1823.325,3457.849 A1262.613,1262.613 40.000 0,1 1819.830,3448.765 L1773.095,3466.536 A1312.613,1312.613 0.000 0,0 1776.728,3475.980 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2656_1677_1_substitution_" tilersid="rs1016777825" class="tile" dbsource="dbSNP"/>
<path d="M1818.109,3444.213 A1262.613,1262.613 40.000 0,1 1811.401,3425.939 L1764.332,3442.806 A1312.613,1312.613 0.000 0,0 1771.306,3461.804 Z" style="stroke-linecap:round;fill:rgb(255,0,255);" class="tile" dbsource="dbSNP" id="tile4210_1683_2_insertion_frameshift" tilersid="rs1293919180"/>
<path d="M1809.768,3421.354 A1262.613,1262.613 40.000 0,1 1806.556,3412.166 L1759.295,3428.488 A1312.613,1312.613 0.000 0,0 1762.635,3438.040 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs375352455" id="tile263_1688_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1803.414,3402.954 A1262.613,1262.613 40.000 0,1 1800.343,3393.718 L1752.836,3409.309 A1312.613,1312.613 0.000 0,0 1756.029,3418.911 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs750955307" id="tile460_1693_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1797.344,3384.458 A1262.613,1262.613 40.000 0,1 1794.416,3375.176 L1746.674,3390.033 A1312.613,1312.613 0.000 0,0 1749.718,3399.683 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3501_1699_1_substitution_" tilersid="rs1212751713" class="tile" dbsource="dbSNP"/>
<path d="M1732.352,3394.490 A1327.613,1327.613 40.000 0,1 1729.348,3384.706 L1681.493,3399.195 A1377.613,1377.613 0.000 0,0 1684.610,3409.347 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1029163828" id="tile2765_1704_1_substitution_"/>
<path d="M1788.775,3356.545 A1262.613,1262.613 40.000 0,1 1786.062,3347.197 L1737.990,3360.946 A1312.613,1312.613 0.000 0,0 1740.810,3370.664 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1305384714" id="tile4310_1709_1_substitution_"/>
<path d="M1783.422,3337.829 A1262.613,1262.613 40.000 0,1 1780.854,3328.440 L1732.575,3341.447 A1312.613,1312.613 0.000 0,0 1735.245,3351.207 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1266676599" id="tile3974_1716_1_substitution_"/>
<path d="M1718.092,3345.349 A1327.613,1327.613 40.000 0,1 1715.467,3335.457 L1667.090,3348.090 A1377.613,1377.613 0.000 0,0 1669.813,3358.355 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1303528080" id="tile4298_1718_1_substitution_"/>
<path d="M1778.358,3319.033 A1262.613,1262.613 40.000 0,1 1775.935,3309.606 L1727.462,3321.866 A1312.613,1312.613 0.000 0,0 1729.981,3331.666 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1406604641" id="tile5129_1720_1_substitution_"/>
<path d="M1712.920,3325.544 A1327.613,1327.613 40.000 0,1 1710.448,3315.613 L1661.882,3327.500 A1377.613,1377.613 0.000 0,0 1664.446,3337.805 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4818_1723_1_substitution_" tilersid="rs1367658189" class="tile" dbsource="dbSNP"/>
<path d="M1764.914,3262.207 A1262.613,1262.613 40.000 0,1 1762.929,3252.678 L1713.941,3262.684 A1312.613,1312.613 0.000 0,0 1716.004,3272.590 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1447811956" id="tile5484_1740_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1761.018,3243.134 A1262.613,1262.613 40.000 0,1 1759.181,3233.576 L1710.044,3242.826 A1312.613,1312.613 0.000 0,0 1711.954,3252.763 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs372924787" id="tile235_1746_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1697.235,3255.651 A1327.613,1327.613 40.000 0,1 1695.303,3245.601 L1646.166,3254.850 A1377.613,1377.613 0.000 0,0 1648.170,3265.279 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile852_1745_1_substitution_" tilersid="rs150172355"/>
<path d="M1757.417,3224.004 A1262.613,1262.613 40.000 0,1 1755.727,3214.419 L1706.453,3222.910 A1312.613,1312.613 0.000 0,0 1708.210,3232.875 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1362_1752_1_substitution_" tilersid="rs776791252" class="tile" dbsource="dbSNP"/>
<path d="M1691.671,3225.457 A1327.613,1327.613 40.000 0,1 1689.972,3215.365 L1640.634,3223.476 A1377.613,1377.613 0.000 0,0 1642.398,3233.948 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3169_1754_1_substitution_" tilersid="rs1173089368" class="tile" dbsource="dbSNP"/>
<path d="M1754.111,3204.820 A1262.613,1262.613 40.000 0,1 1752.569,3195.210 L1703.171,3202.940 A1312.613,1312.613 0.000 0,0 1704.773,3212.931 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1160_1756_1_substitution_" tilersid="rs768685219" class="tile" dbsource="dbSNP"/>
<path d="M1688.351,3205.260 A1327.613,1327.613 40.000 0,1 1686.808,3195.142 L1637.351,3202.492 A1377.613,1377.613 0.000 0,0 1638.952,3212.990 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1423623219" id="tile5265_1761_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1751.102,3185.588 A1262.613,1262.613 40.000 0,1 1749.708,3175.955 L1700.196,3182.923 A1312.613,1312.613 0.000 0,0 1701.645,3192.937 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile969_1763_1_substitution_" tilersid="rs760929786"/>
<path d="M1685.342,3185.013 A1327.613,1327.613 40.000 0,1 1683.955,3174.874 L1634.391,3181.460 A1377.613,1377.613 0.000 0,0 1635.830,3191.981 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1328_1767_1_substitution_" tilersid="rs775671955" class="tile" dbsource="dbSNP"/>
<path d="M1814.074,3166.897 A1197.613,1197.613 40.000 0,1 1812.822,3157.750 L1763.258,3164.336 A1247.613,1247.613 0.000 0,0 1764.562,3173.865 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5775_1766_1_substitution_" tilersid="rs1481648983"/>
<path d="M1747.144,3156.658 A1262.613,1262.613 40.000 0,1 1745.973,3146.996 L1696.313,3152.817 A1312.613,1312.613 0.000 0,0 1697.530,3162.862 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs776189364" id="tile1352_1771_1_substitution_"/>
<path d="M1744.878,3137.324 A1262.613,1262.613 40.000 0,1 1743.856,3127.645 L1694.112,3132.700 A1312.613,1312.613 0.000 0,0 1695.174,3142.763 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile801_1778_1_substitution_" tilersid="rs140857723"/>
<path d="M1742.910,3117.958 A1262.613,1262.613 40.000 0,1 1742.038,3108.264 L1692.222,3112.551 A1312.613,1312.613 0.000 0,0 1693.128,3122.629 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs148036434" id="tile834_1783_1_substitution_"/>
<path d="M1678.194,3124.030 A1327.613,1327.613 40.000 0,1 1677.277,3113.837 L1627.461,3118.124 A1377.613,1377.613 0.000 0,0 1628.413,3128.701 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3273_1785_1_substitution_" tilersid="rs1184569811"/>
<path d="M1741.240,3098.563 A1262.613,1262.613 40.000 0,1 1740.518,3088.857 L1690.642,3092.375 A1312.613,1312.613 0.000 0,0 1691.393,3102.466 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs145437639" id="tile821_1791_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1739.870,3079.145 A1262.613,1262.613 40.000 0,1 1739.298,3069.429 L1689.373,3072.178 A1312.613,1312.613 0.000 0,0 1689.969,3082.279 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3078_1797_1_substitution_" tilersid="rs1162138115" class="tile" dbsource="dbSNP"/>
<path d="M1674.998,3083.219 A1327.613,1327.613 40.000 0,1 1674.396,3073.003 L1624.472,3075.752 A1377.613,1377.613 0.000 0,0 1625.097,3086.354 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1423289421" id="tile5274_1796_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1738.029,3040.257 A1262.613,1262.613 40.000 0,1 1737.757,3030.528 L1687.771,3031.736 A1312.613,1312.613 0.000 0,0 1688.055,3041.851 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2579_1809_1_substitution_" tilersid="rs1005566006"/>
<path d="M1737.388,3001.331 A1262.613,1262.613 40.000 0,1 1737.415,2991.598 L1687.417,2991.265 A1312.613,1312.613 0.000 0,0 1687.388,3001.383 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5092_1819_1_substitution_" tilersid="rs1402111758" class="tile" dbsource="dbSNP"/>
<path d="M1672.417,2991.165 A1327.613,1327.613 40.000 0,1 1672.524,2980.931 L1622.530,2980.213 A1377.613,1377.613 0.000 0,0 1622.418,2990.832 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs769786221" id="tile1205_1822_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1802.414,2992.030 A1197.613,1197.613 40.000 0,1 1802.511,2982.798 L1752.516,2982.080 A1247.613,1247.613 0.000 0,0 1752.415,2991.697 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1201908212" id="tile3415_1823_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1737.518,2981.865 A1262.613,1262.613 40.000 0,1 1737.695,2972.133 L1687.707,2971.030 A1312.613,1312.613 0.000 0,0 1687.523,2981.147 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs747988885" id="tile393_1825_1_substitution_"/>
<path d="M1739.154,2933.229 A1262.613,1262.613 40.000 0,1 1739.706,2923.511 L1689.798,2920.482 A1312.613,1312.613 0.000 0,0 1689.224,2930.585 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs201715513" id="tile159_1840_1_substitution_"/>
<path d="M1674.826,2919.574 A1327.613,1327.613 40.000 0,1 1675.485,2909.361 L1625.602,2905.947 A1377.613,1377.613 0.000 0,0 1624.918,2916.545 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs773083611" id="tile1275_1844_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1804.587,2927.449 A1197.613,1197.613 40.000 0,1 1805.182,2918.236 L1755.299,2914.822 A1247.613,1247.613 0.000 0,0 1754.679,2924.420 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1408702726" id="tile5141_1843_1_substitution_"/>
<path d="M1750.713,2817.045 A1262.613,1262.613 40.000 0,1 1752.161,2807.420 L1702.746,2799.794 A1312.613,1312.613 0.000 0,0 1701.241,2809.800 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1216_1878_1_substitution_" tilersid="rs769444182" class="tile" dbsource="dbSNP"/>
<path d="M1687.921,2797.506 A1327.613,1327.613 40.000 0,1 1689.521,2787.397 L1640.166,2779.390 A1377.613,1377.613 0.000 0,0 1638.506,2789.879 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs748163894" id="tile396_1880_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1755.278,2788.205 A1262.613,1262.613 40.000 0,1 1756.948,2778.616 L1707.722,2769.849 A1312.613,1312.613 0.000 0,0 1705.986,2779.818 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs776696484" id="tile1349_1886_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1692.955,2767.219 A1327.613,1327.613 40.000 0,1 1694.788,2757.150 L1645.631,2748.004 A1377.613,1377.613 0.000 0,0 1643.729,2758.452 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs140312271" id="tile789_1888_1_substitution_"/>
<path d="M1820.941,2790.013 A1197.613,1197.613 40.000 0,1 1822.594,2780.930 L1773.438,2771.784 A1247.613,1247.613 0.000 0,0 1771.715,2781.246 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5356_1890_1_substitution_" tilersid="rs1433836817"/>
<path d="M1762.399,2749.930 A1262.613,1262.613 40.000 0,1 1764.364,2740.397 L1715.432,2730.117 A1312.613,1312.613 0.000 0,0 1713.390,2740.027 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1144_1899_1_substitution_" tilersid="rs767537469"/>
<path d="M1698.687,2737.056 A1327.613,1327.613 40.000 0,1 1700.753,2727.033 L1651.821,2716.752 A1377.613,1377.613 0.000 0,0 1649.677,2727.153 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3704_1898_1_substitution_" tilersid="rs1238269881"/>
<path d="M1766.402,2730.880 A1262.613,1262.613 40.000 0,1 1768.513,2721.378 L1719.746,2710.344 A1312.613,1312.613 0.000 0,0 1717.551,2720.222 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1569236210" id="tile5877_1903_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1705.115,2707.034 A1327.613,1327.613 40.000 0,1 1707.412,2697.061 L1658.731,2685.652 A1377.613,1377.613 0.000 0,0 1656.348,2696.001 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4400_1908_1_substitution_" tilersid="rs1315819425" class="tile" dbsource="dbSNP"/>
<path d="M1772.955,2702.425 A1262.613,1262.613 40.000 0,1 1775.285,2692.975 L1726.786,2680.817 A1312.613,1312.613 0.000 0,0 1724.363,2690.641 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs183135788" id="tile23_1913_1_substitution_"/>
<path d="M1780.164,2674.130 A1262.613,1262.613 40.000 0,1 1782.713,2664.736 L1734.508,2651.460 A1312.613,1312.613 0.000 0,0 1731.858,2661.225 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4585_1922_1_substitution_" tilersid="rs1339201462" class="tile" dbsource="dbSNP"/>
<path d="M1720.046,2647.477 A1327.613,1327.613 40.000 0,1 1722.802,2637.620 L1674.700,2623.973 A1377.613,1377.613 0.000 0,0 1671.841,2634.200 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1527_1924_1_substitution_" tilersid="rs868528474"/>
<path d="M1788.026,2646.009 A1262.613,1262.613 40.000 0,1 1790.791,2636.677 L1742.906,2622.289 A1312.613,1312.613 0.000 0,0 1740.031,2631.991 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5327_1932_1_substitution_" tilersid="rs1431656720"/>
<path d="M1812.147,2571.986 A1262.613,1262.613 40.000 0,1 1815.482,2562.842 L1768.574,2545.530 A1312.613,1312.613 0.000 0,0 1765.108,2555.037 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4547_1955_1_substitution_" tilersid="rs1334127098" class="tile" dbsource="dbSNP"/>
<path d="M1754.502,2540.337 A1327.613,1327.613 40.000 0,1 1758.083,2530.749 L1711.310,2513.077 A1377.613,1377.613 0.000 0,0 1707.595,2523.025 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1304_1959_1_substitution_" tilersid="rs774412370"/>
<path d="M1818.887,2553.724 A1262.613,1262.613 40.000 0,1 1822.362,2544.632 L1775.727,2526.599 A1312.613,1312.613 0.000 0,0 1772.114,2536.051 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1479485636" id="tile5762_1961_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1825.908,2535.568 A1262.613,1262.613 40.000 0,1 1829.523,2526.531 L1783.171,2507.781 A1312.613,1312.613 0.000 0,0 1779.413,2517.176 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs199951323" id="tile147_1967_1_substitution_"/>
<path d="M1833.207,2517.522 A1262.613,1262.613 40.000 0,1 1836.961,2508.542 L1790.905,2489.080 A1312.613,1312.613 0.000 0,0 1787.002,2498.415 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4216_1972_1_substitution_" tilersid="rs1295899858"/>
<path d="M1773.140,2492.683 A1327.613,1327.613 40.000 0,1 1777.087,2483.241 L1731.031,2463.779 A1377.613,1377.613 0.000 0,0 1726.935,2473.577 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1418717992" id="tile5220_1974_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1840.784,2499.591 A1262.613,1262.613 40.000 0,1 1844.676,2490.669 L1798.925,2470.500 A1312.613,1312.613 0.000 0,0 1794.879,2479.774 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile989_1979_1_substitution_" tilersid="rs761507256" class="tile" dbsource="dbSNP"/>
<path d="M1869.462,2437.796 A1262.613,1262.613 40.000 0,1 1873.829,2429.098 L1829.232,2406.490 A1312.613,1312.613 0.000 0,0 1824.692,2415.532 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1192635576" id="tile3379_2000_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1815.853,2399.707 A1327.613,1327.613 40.000 0,1 1820.516,2390.597 L1776.095,2367.646 A1377.613,1377.613 0.000 0,0 1771.256,2377.099 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile151_2002_1_substitution_" tilersid="rs200180615" class="tile" dbsource="dbSNP"/>
<path d="M1882.765,2411.803 A1262.613,1262.613 40.000 0,1 1887.332,2403.208 L1843.270,2379.575 A1312.613,1312.613 0.000 0,0 1838.522,2388.510 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1250368104" id="tile3834_2009_1_substitution_"/>
<path d="M1830.051,2372.485 A1327.613,1327.613 40.000 0,1 1834.924,2363.485 L1791.045,2339.513 A1377.613,1377.613 0.000 0,0 1785.989,2348.852 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile634_2012_1_substitution_" tilersid="rs753705431" class="tile" dbsource="dbSNP"/>
<path d="M1891.966,2394.649 A1262.613,1262.613 40.000 0,1 1896.665,2386.125 L1852.973,2361.815 A1312.613,1312.613 0.000 0,0 1848.087,2370.676 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs763939235" id="tile1045_2014_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1949.008,2425.812 A1197.613,1197.613 40.000 0,1 1953.465,2417.728 L1909.773,2393.418 A1247.613,1247.613 0.000 0,0 1905.129,2401.840 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1449878623" id="tile5501_2015_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1839.865,2354.522 A1327.613,1327.613 40.000 0,1 1844.875,2345.598 L1801.371,2320.952 A1377.613,1377.613 0.000 0,0 1796.172,2330.213 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1027571965" id="tile2751_2018_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1916.116,2352.400 A1262.613,1262.613 40.000 0,1 1921.140,2344.064 L1878.417,2318.089 A1312.613,1312.613 0.000 0,0 1873.193,2326.755 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs760732432" id="tile955_2030_1_substitution_"/>
<path d="M1860.317,2319.062 A1327.613,1327.613 40.000 0,1 1865.600,2310.296 L1822.876,2284.321 A1377.613,1377.613 0.000 0,0 1817.394,2293.416 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1340_2031_1_substitution_" tilersid="rs775548770"/>
<path d="M1976.680,2377.832 A1197.613,1197.613 40.000 0,1 1981.507,2369.962 L1938.985,2343.658 A1247.613,1247.613 0.000 0,0 1933.957,2351.857 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1271264671" id="tile4002_2033_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1926.229,2335.767 A1262.613,1262.613 40.000 0,1 1931.381,2327.509 L1889.063,2300.878 A1312.613,1312.613 0.000 0,0 1883.707,2309.463 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs771673051" id="tile1247_2035_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1876.368,2292.889 A1327.613,1327.613 40.000 0,1 1881.852,2284.248 L1839.741,2257.292 A1377.613,1377.613 0.000 0,0 1834.050,2266.258 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs758968315" id="tile922_2040_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1936.597,2319.292 A1262.613,1262.613 40.000 0,1 1941.876,2311.114 L1899.974,2283.834 A1312.613,1312.613 0.000 0,0 1894.486,2292.335 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1346564574" id="tile4648_2041_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1947.218,2302.978 A1262.613,1262.613 40.000 0,1 1952.622,2294.883 L1911.146,2266.960 A1312.613,1312.613 0.000 0,0 1905.527,2275.376 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1307_2049_1_substitution_" tilersid="rs773848804" class="tile" dbsource="dbSNP"/>
<path d="M1898.703,2258.583 A1327.613,1327.613 40.000 0,1 1904.451,2250.116 L1863.191,2221.874 A1377.613,1377.613 0.000 0,0 1857.226,2230.660 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs770503198" id="tile1197_2052_1_substitution_"/>
<path d="M1958.089,2286.830 A1262.613,1262.613 40.000 0,1 1963.617,2278.819 L1922.576,2250.260 A1312.613,1312.613 0.000 0,0 1916.829,2258.588 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1262476548" id="tile3933_2053_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1969.208,2270.852 A1262.613,1262.613 40.000 0,1 1974.859,2262.927 L1934.263,2233.739 A1312.613,1312.613 0.000 0,0 1928.388,2241.977 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1430341453" id="tile5323_2061_1_substitution_"/>
<path d="M1922.084,2224.982 A1327.613,1327.613 40.000 0,1 1928.091,2216.696 L1887.721,2187.195 A1377.613,1377.613 0.000 0,0 1881.488,2195.794 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4134_2063_1_substitution_" tilersid="rs1284743203"/>
<path d="M1980.571,2255.046 A1262.613,1262.613 40.000 0,1 1986.344,2247.210 L1946.203,2217.399 A1312.613,1312.613 0.000 0,0 1940.202,2225.546 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs777410473" id="tile1420_2065_1_substitution_"/>
<path d="M1934.161,2208.456 A1327.613,1327.613 40.000 0,1 1940.294,2200.263 L1900.384,2170.144 A1377.613,1377.613 0.000 0,0 1894.020,2178.645 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs4646179" id="tile608_2070_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2038.528,2285.964 A1197.613,1197.613 40.000 0,1 2044.061,2278.574 L2004.151,2248.454 A1247.613,1247.613 0.000 0,0 1998.387,2256.153 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5870_2069_1_substitution_" tilersid="rs1569235723" class="tile" dbsource="dbSNP"/>
<path d="M1992.178,2239.418 A1262.613,1262.613 40.000 0,1 1998.071,2231.672 L1958.394,2201.246 A1312.613,1312.613 0.000 0,0 1952.267,2209.299 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs770114482" id="tile1185_2073_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M1946.491,2192.118 A1327.613,1327.613 40.000 0,1 1952.750,2184.021 L1913.309,2153.290 A1377.613,1377.613 0.000 0,0 1906.814,2161.692 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs149039346" id="tile841_2074_1_substitution_"/>
<path d="M2004.023,2223.971 A1262.613,1262.613 40.000 0,1 2010.035,2216.316 L1970.832,2185.282 A1312.613,1312.613 0.000 0,0 1964.582,2193.240 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1481_2078_1_substitution_" tilersid="rs781544129" class="tile" dbsource="dbSNP"/>
<path d="M2055.297,2263.921 A1197.613,1197.613 40.000 0,1 2060.999,2256.661 L2021.796,2225.627 A1247.613,1247.613 0.000 0,0 2015.856,2233.190 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5597_2077_1_substitution_" tilersid="rs1462355609"/>
<path d="M2022.235,2201.147 A1262.613,1262.613 40.000 0,1 2028.422,2193.634 L1989.947,2161.701 A1312.613,1312.613 0.000 0,0 1983.515,2169.512 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs755445931" id="tile681_2086_1_substitution_"/>
<path d="M1978.405,2152.121 A1327.613,1327.613 40.000 0,1 1984.971,2144.271 L1946.744,2112.043 A1377.613,1377.613 0.000 0,0 1939.930,2120.189 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs751603885" id="tile481_2089_1_substitution_"/>
<path d="M2040.969,2178.751 A1262.613,1262.613 40.000 0,1 2047.329,2171.382 L2009.603,2138.568 A1312.613,1312.613 0.000 0,0 2002.991,2146.229 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile795_2097_1_substitution_" tilersid="rs113789216" class="tile" dbsource="dbSNP"/>
<path d="M1998.285,2128.724 A1327.613,1327.613 40.000 0,1 2005.031,2121.028 L1967.559,2087.925 A1377.613,1377.613 0.000 0,0 1960.559,2095.911 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5021_2098_1_substitution_" tilersid="rs1392981937"/>
<path d="M2056.974,2160.422 A1262.613,1262.613 40.000 0,1 2070.030,2145.983 L2033.202,2112.163 A1312.613,1312.613 0.000 0,0 2019.630,2127.174 Z" style="stroke-linecap:round;fill:rgb(255,0,255);" dbsource="dbSNP" class="tile" tilersid="rs1431172217" id="tile5353_2102_2_deletion_frameshift"/>
<path d="M2018.700,2105.793 A1327.613,1327.613 40.000 0,1 2025.623,2098.255 L1988.926,2064.294 A1377.613,1377.613 0.000 0,0 1981.743,2072.116 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1458_2107_1_substitution_" tilersid="rs780128908" class="tile" dbsource="dbSNP"/>
<path d="M2086.660,2128.220 A1262.613,1262.613 40.000 0,1 2093.408,2121.205 L2057.506,2086.404 A1312.613,1312.613 0.000 0,0 2050.491,2093.697 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs372986872" id="tile236_2118_1_substitution_"/>
<path d="M2100.209,2114.243 A1262.613,1262.613 40.000 0,1 2107.064,2107.333 L2071.703,2071.983 A1312.613,1312.613 0.000 0,0 2064.577,2079.166 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1189_2123_1_substitution_" tilersid="rs769062069" class="tile" dbsource="dbSNP"/>
<path d="M2053.887,2068.643 A1327.613,1327.613 40.000 0,1 2061.095,2061.378 L2025.734,2026.028 A1377.613,1377.613 0.000 0,0 2018.255,2033.567 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs776995986" id="tile1365_2122_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2153.033,2153.288 A1197.613,1197.613 40.000 0,1 2159.585,2146.784 L2124.498,2111.162 A1247.613,1247.613 0.000 0,0 2117.672,2117.938 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1052746182" id="tile2975_2125_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2113.972,2100.476 A1262.613,1262.613 40.000 0,1 2120.932,2093.672 L2086.121,2057.781 A1312.613,1312.613 0.000 0,0 2078.885,2064.854 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs370187012" id="tile216_2129_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2068.358,2054.168 A1327.613,1327.613 40.000 0,1 2075.677,2047.014 L2040.866,2011.123 A1377.613,1377.613 0.000 0,0 2033.271,2018.546 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs901495523" id="tile1684_2128_1_substitution_"/>
<path d="M2127.945,2086.923 A1262.613,1262.613 40.000 0,1 2135.010,2080.227 L2100.756,2043.804 A1312.613,1312.613 0.000 0,0 2093.411,2050.764 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1173472683" id="tile3175_2135_1_substitution_"/>
<path d="M2149.293,2067.001 A1262.613,1262.613 40.000 0,1 2156.510,2060.471 L2123.108,2023.265 A1312.613,1312.613 0.000 0,0 2115.604,2030.054 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3191_2145_1_substitution_" tilersid="rs1174145055"/>
<path d="M2113.087,2012.103 A1327.613,1327.613 40.000 0,1 2120.729,2005.296 L2087.614,1967.834 A1377.613,1377.613 0.000 0,0 2079.684,1974.898 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs200540199" id="tile178_2147_1_substitution_"/>
<path d="M2199.933,2108.838 A1197.613,1197.613 40.000 0,1 2206.827,2102.697 L2173.712,2065.235 A1247.613,1247.613 0.000 0,0 2166.531,2071.633 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile820_2146_1_substitution_" tilersid="rs144869363" class="tile" dbsource="dbSNP"/>
<path d="M2178.462,2041.217 A1262.613,1262.613 40.000 0,1 2185.877,2034.912 L2153.638,1996.694 A1312.613,1312.613 0.000 0,0 2145.928,2003.249 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4676_2157_1_substitution_" tilersid="rs1350774050" class="tile" dbsource="dbSNP"/>
<path d="M2143.966,1985.229 A1327.613,1327.613 40.000 0,1 2151.814,1978.660 L2119.870,1940.195 A1377.613,1377.613 0.000 0,0 2111.726,1947.011 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs746153383" id="tile340_2159_1_substitution_"/>
<path d="M2227.789,2084.595 A1197.613,1197.613 40.000 0,1 2234.868,2078.670 L2202.924,2040.205 A1247.613,1247.613 0.000 0,0 2195.549,2046.378 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs41303171" id="tile747_2158_1_substitution_"/>
<path d="M2208.412,2016.344 A1262.613,1262.613 40.000 0,1 2216.018,2010.271 L2184.972,1971.078 A1312.613,1312.613 0.000 0,0 2177.065,1977.391 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1384877595" id="tile4947_2169_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2231.370,1998.302 A1262.613,1262.613 40.000 0,1 2239.115,1992.407 L2208.984,1952.506 A1312.613,1312.613 0.000 0,0 2200.932,1958.634 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs752452705" id="tile527_2178_1_substitution_"/>
<path d="M2191.801,1946.734 A1327.613,1327.613 40.000 0,1 2199.944,1940.535 L2169.813,1900.634 A1377.613,1377.613 0.000 0,0 2161.363,1907.067 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile798_2176_1_substitution_" tilersid="rs139980377" class="tile" dbsource="dbSNP"/>
<path d="M2270.940,2049.870 A1197.613,1197.613 40.000 0,1 2278.286,2044.278 L2248.154,2004.377 A1247.613,1247.613 0.000 0,0 2240.502,2010.202 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile884_2177_1_substitution_" tilersid="rs757492005" class="tile" dbsource="dbSNP"/>
<path d="M2254.739,1980.796 A1262.613,1262.613 40.000 0,1 2262.618,1975.081 L2233.418,1934.494 A1312.613,1312.613 0.000 0,0 2225.227,1940.435 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs375923132" id="tile273_2186_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2224.658,1922.318 A1327.613,1327.613 40.000 0,1 2232.988,1916.373 L2204.101,1875.562 A1377.613,1377.613 0.000 0,0 2195.457,1881.730 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5250_2189_1_substitution_" tilersid="rs1421749672" class="tile" dbsource="dbSNP"/>
<path d="M2300.579,2027.845 A1197.613,1197.613 40.000 0,1 2308.094,2022.482 L2279.207,1981.671 A1247.613,1247.613 0.000 0,0 2271.379,1987.257 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1444714998" id="tile5449_2190_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2270.541,1969.427 A1262.613,1262.613 40.000 0,1 2278.507,1963.835 L2249.936,1922.802 A1312.613,1312.613 0.000 0,0 2241.654,1928.616 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile828_2191_1_substitution_" tilersid="rs147311723"/>
<path d="M2294.568,1952.835 A1262.613,1262.613 40.000 0,1 2302.661,1947.428 L2275.046,1905.745 A1312.613,1312.613 0.000 0,0 2266.632,1911.366 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile475_2201_1_substitution_" tilersid="rs751484521"/>
<path d="M2266.762,1893.241 A1327.613,1327.613 40.000 0,1 2275.315,1887.621 L2248.022,1845.727 A1377.613,1377.613 0.000 0,0 2239.147,1851.558 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1445361759" id="tile5461_2205_1_substitution_"/>
<path d="M2318.971,1936.802 A1262.613,1262.613 40.000 0,1 2327.188,1931.584 L2300.544,1889.274 A1312.613,1312.613 0.000 0,0 2292.002,1894.699 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs1416534293" id="tile5202_2209_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2343.739,1921.338 A1262.613,1262.613 40.000 0,1 2352.074,1916.311 L2326.416,1873.396 A1312.613,1312.613 0.000 0,0 2317.751,1878.622 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3914_2218_1_substitution_" tilersid="rs1259850376"/>
<path d="M2309.955,1865.808 A1327.613,1327.613 40.000 0,1 2318.718,1860.522 L2293.060,1817.607 A1377.613,1377.613 0.000 0,0 2283.967,1823.092 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4851_2219_1_substitution_" tilersid="rs1371764870"/>
<path d="M2385.430,1972.100 A1197.613,1197.613 40.000 0,1 2393.372,1967.393 L2368.045,1924.282 A1247.613,1247.613 0.000 0,0 2359.772,1929.185 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs372923812" id="tile234_2221_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2368.858,1906.450 A1262.613,1262.613 40.000 0,1 2377.307,1901.618 L2352.648,1858.121 A1312.613,1312.613 0.000 0,0 2343.865,1863.145 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs762444602" id="tile1007_2229_1_substitution_"/>
<path d="M2385.793,1896.850 A1262.613,1262.613 40.000 0,1 2394.315,1892.148 L2370.330,1848.277 A1312.613,1312.613 0.000 0,0 2361.470,1853.165 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs772641644" id="tile1280_2233_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2411.467,1882.942 A1262.613,1262.613 40.000 0,1 2420.095,1878.438 L2397.131,1834.024 A1312.613,1312.613 0.000 0,0 2388.161,1838.706 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile2067_2242_1_substitution_" tilersid="rs947732783"/>
<path d="M2390.242,1820.700 A1327.613,1327.613 40.000 0,1 2399.351,1816.034 L2376.729,1771.444 A1377.613,1377.613 0.000 0,0 2367.277,1776.285 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs35803318" id="tile743_2247_1_substitution_"/>
<path d="M2437.455,1869.631 A1262.613,1262.613 40.000 0,1 2446.186,1865.328 L2424.255,1820.395 A1312.613,1312.613 0.000 0,0 2415.178,1824.868 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile983_2252_1_substitution_" tilersid="rs761405491"/>
<path d="M2454.949,1861.093 A1262.613,1262.613 40.000 0,1 2463.745,1856.925 L2442.509,1811.659 A1312.613,1312.613 0.000 0,0 2433.365,1815.991 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1364_2259_1_substitution_" tilersid="rs776886768" class="tile" dbsource="dbSNP"/>
<path d="M2426.890,1802.461 A1327.613,1327.613 40.000 0,1 2436.138,1798.079 L2414.902,1752.812 A1377.613,1377.613 0.000 0,0 2405.306,1757.360 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3919_2257_1_substitution_" tilersid="rs1260616687" class="tile" dbsource="dbSNP"/>
<path d="M2490.321,1844.830 A1262.613,1262.613 40.000 0,1 2499.242,1840.935 L2479.411,1795.036 A1312.613,1312.613 0.000 0,0 2470.138,1799.085 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs931448406" id="tile1927_2270_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2526.178,1829.665 A1262.613,1262.613 40.000 0,1 2535.214,1826.048 L2516.808,1779.559 A1312.613,1312.613 0.000 0,0 2507.415,1783.320 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile1188_2281_1_substitution_" tilersid="rs769030917" class="tile" dbsource="dbSNP"/>
<path d="M2511.287,1765.612 A1327.613,1327.613 40.000 0,1 2520.817,1761.881 L2502.770,1715.252 A1377.613,1377.613 0.000 0,0 2492.881,1719.123 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile2018_2286_1_substitution_" tilersid="rs943387084" class="tile" dbsource="dbSNP"/>
<path d="M2580.797,1809.009 A1262.613,1262.613 40.000 0,1 2589.991,1805.813 L2573.754,1758.523 A1312.613,1312.613 0.000 0,0 2564.197,1761.845 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs747516757" id="tile385_2299_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2568.883,1744.336 A1327.613,1327.613 40.000 0,1 2578.576,1741.049 L2562.704,1693.635 A1377.613,1377.613 0.000 0,0 2552.647,1697.045 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile799_2302_1_substitution_" tilersid="rs140016715" class="tile" dbsource="dbSNP"/>
<path d="M2599.209,1802.688 A1262.613,1262.613 40.000 0,1 2608.450,1799.634 L2592.945,1752.099 A1312.613,1312.613 0.000 0,0 2583.337,1755.274 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs772347875" id="tile1261_2305_1_substitution_"/>
<path d="M2617.715,1796.651 A1262.613,1262.613 40.000 0,1 2627.003,1793.740 L2612.232,1745.971 A1312.613,1312.613 0.000 0,0 2602.577,1748.998 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs1323382709" id="tile4478_2312_1_substitution_"/>
<path d="M2607.801,1731.641 A1327.613,1327.613 40.000 0,1 2617.590,1728.655 L2603.188,1680.774 A1377.613,1377.613 0.000 0,0 2593.030,1683.873 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" dbsource="dbSNP" class="tile" tilersid="rs764682532" id="tile1057_2315_1_substitution_"/>
<path d="M2645.644,1788.133 A1262.613,1262.613 40.000 0,1 2654.997,1785.437 L2641.334,1737.340 A1312.613,1312.613 0.000 0,0 2631.612,1740.142 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile984_2320_1_substitution_" tilersid="rs761408882" class="tile" dbsource="dbSNP"/>
<path d="M2627.402,1725.745 A1327.613,1327.613 40.000 0,1 2637.236,1722.911 L2623.574,1674.813 A1377.613,1377.613 0.000 0,0 2613.369,1677.755 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile1052_2322_1_substitution_" tilersid="rs764422604"/>
<path d="M2663.887,1850.520 A1197.613,1197.613 40.000 0,1 2672.758,1847.963 L2659.095,1799.866 A1247.613,1247.613 0.000 0,0 2649.854,1802.530 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4326_2321_1_substitution_" tilersid="rs1307986087" class="tile" dbsource="dbSNP"/>
<path d="M2664.370,1782.814 A1262.613,1262.613 40.000 0,1 2673.763,1780.262 L2660.844,1731.960 A1312.613,1312.613 0.000 0,0 2651.079,1734.613 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3639_2328_1_substitution_" tilersid="rs1228927272"/>
<path d="M2656.968,1717.470 A1327.613,1327.613 40.000 0,1 2666.865,1714.863 L2654.318,1666.463 A1377.613,1377.613 0.000 0,0 2644.049,1669.168 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile261_2331_1_substitution_" tilersid="rs375252585" class="tile" dbsource="dbSNP"/>
<path d="M2711.523,1770.784 A1262.613,1262.613 40.000 0,1 2721.007,1768.597 L2709.959,1719.833 A1312.613,1312.613 0.000 0,0 2700.099,1722.107 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs902013280" id="tile1687_2341_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2696.672,1707.504 A1327.613,1327.613 40.000 0,1 2706.645,1705.204 L2695.596,1656.440 A1377.613,1377.613 0.000 0,0 2685.248,1658.826 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile4072_2343_1_substitution_" tilersid="rs1277737097"/>
<path d="M2735.370,1831.990 A1197.613,1197.613 40.000 0,1 2744.382,1829.985 L2733.710,1781.137 A1247.613,1247.613 0.000 0,0 2724.322,1783.226 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile832_2345_1_substitution_" tilersid="rs147487891" class="tile" dbsource="dbSNP"/>
<path d="M2730.508,1766.483 A1262.613,1262.613 40.000 0,1 2740.025,1764.442 L2729.730,1715.513 A1312.613,1312.613 0.000 0,0 2719.836,1717.635 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3903_2348_1_substitution_" tilersid="rs1258561133" class="tile" dbsource="dbSNP"/>
<path d="M2726.641,1700.835 A1327.613,1327.613 40.000 0,1 2736.664,1698.766 L2726.747,1649.760 A1377.613,1377.613 0.000 0,0 2716.346,1651.906 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile998_2352_1_substitution_" tilersid="rs760076142"/>
<path d="M2749.557,1762.475 A1262.613,1262.613 40.000 0,1 2759.105,1760.581 L2749.565,1711.499 A1312.613,1312.613 0.000 0,0 2739.640,1713.468 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile239_2353_1_substitution_" tilersid="rs373153165"/>
<path d="M2762.450,1826.183 A1197.613,1197.613 40.000 0,1 2771.506,1824.387 L2761.966,1775.305 A1247.613,1247.613 0.000 0,0 2752.533,1777.177 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile3806_2354_1_substitution_" tilersid="rs1248729689"/>
<path d="M2826.304,1749.392 A1262.613,1262.613 40.000 0,1 2835.950,1748.090 L2829.453,1698.514 A1312.613,1312.613 0.000 0,0 2819.426,1699.868 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5570_2378_1_substitution_" tilersid="rs1457512583" class="tile" dbsource="dbSNP"/>
<path d="M2827.505,1683.641 A1327.613,1327.613 40.000 0,1 2837.657,1682.351 L2831.543,1632.726 A1377.613,1377.613 0.000 0,0 2821.008,1634.065 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5388_2380_1_substitution_" tilersid="rs1437492704"/>
<path d="M2855.270,1745.710 A1262.613,1262.613 40.000 0,1 2864.944,1744.631 L2859.595,1694.918 A1312.613,1312.613 0.000 0,0 2849.539,1696.039 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile4724_2387_1_substitution_" tilersid="rs1355591379" class="tile" dbsource="dbSNP"/>
<path d="M2874.625,1743.628 A1262.613,1262.613 40.000 0,1 2884.314,1742.699 L2879.732,1692.909 A1312.613,1312.613 0.000 0,0 2869.660,1693.875 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile3176_2392_1_substitution_" tilersid="rs1173491905" class="tile" dbsource="dbSNP"/>
<path d="M2903.711,1741.064 A1262.613,1262.613 40.000 0,1 2913.419,1740.360 L2909.990,1690.477 A1312.613,1312.613 0.000 0,0 2899.898,1691.210 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile5276_2403_1_substitution_" tilersid="rs1423362553" class="tile" dbsource="dbSNP"/>
<path d="M2898.754,1676.254 A1327.613,1327.613 40.000 0,1 2908.962,1675.513 L2905.533,1625.630 A1377.613,1377.613 0.000 0,0 2894.941,1626.399 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" class="tile" dbsource="dbSNP" id="tile5626_2402_1_substitution_" tilersid="rs1464340051"/>
<path d="M2932.849,1739.174 A1262.613,1262.613 40.000 0,1 2942.571,1738.694 L2940.296,1688.746 A1312.613,1312.613 0.000 0,0 2930.190,1689.245 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" tilersid="rs771107251" id="tile1229_2411_1_substitution_" dbsource="dbSNP" class="tile"/>
<path d="M2939.614,1673.762 A1327.613,1327.613 40.000 0,1 2949.840,1673.335 L2947.951,1623.371 A1377.613,1377.613 0.000 0,0 2937.340,1623.813 Z" style="stroke-linecap:round;fill:rgb(203,24,29);" id="tile422_2413_1_substitution_" tilersid="rs749525058" class="tile" dbsource="dbSNP"/>
</g>
<defs>
<pattern id="vline-sparse" width="10" height="10" patternTransform="rotate(0 0 0)" patternUnits="userSpaceOnUse"><line x1="0" y1="0" x2="0" y2="10" style="stroke:black;stroke-width:2" /></pattern>
<pattern id="hline" width="10" height="10" patternTransform="rotate(0 0 0)" patternUnits="userSpaceOnUse"><line x1="0" y1="0" x2="10" y2="0" style="stroke:black;stroke-width:5" /></pattern>
<pattern id="vline" width="10" height="10" patternTransform="rotate(0 0 0)" patternUnits="userSpaceOnUse"><line x1="0" y1="0" x2="0" y2="10" style="stroke:black;stroke-width:5" /></pattern>
<pattern id="checker" width="10" height="10" patternTransform="rotate(45 0 0)" patternUnits="userSpaceOnUse"><line x1="0" y1="0" x2="10" y2="0" style="stroke:black;stroke-width:2" /><line x1="0" y1="0" x2="0" y2="10" style="stroke:black;stroke-width:2" /></pattern>
<pattern id="checker" width="10" height="10" patternTransform="rotate(45 0 0)" patternUnits="userSpaceOnUse"><line x1="0" y1="0" x2="10" y2="0" style="stroke:black;stroke-width:5" /><line x1="0" y1="0" x2="0" y2="10" style="stroke:black;stroke-width:4" /></pattern>
<pattern id="hline-sparse" width="10" height="10" patternTransform="rotate(0 0 0)" patternUnits="userSpaceOnUse"><line x1="0" y1="0" x2="10" y2="0" style="stroke:black;stroke-width:2" /></pattern>
</defs>
</svg>
<script type="text/javascript">
var svg = d3.select("#master").append("svg:g").attr("id","annotation");
svg;
//***Filters***
d3.select("#master").append("svg:defs").attr("id","ExtraS");
d3.select("#ExtraS").append("defs:filter").attr("id","NeonGlow").attr("x",0).attr("y",0);
d3.select("#NeonGlow").append("filter:feColorMatrix").attr("in","SourceGraphic").attr("type","matrix").attr("values","1 0 0 0 0.33, 0 1 0 0 0.33, 0 0 1 0 0.33, 0.5 0.5 0.5 0.5 0.05").attr("result","feColorMatrixOut");
d3.select("#NeonGlow").append("filter:feGaussianBlur").attr("in","feColorMatrixOut").attr("stdDeviation",10).attr("result","feGaussianBlurOut");
d3.select("#NeonGlow").append("filter:feBlend").attr("in","SourceGraphic").attr("in2","feGaussianBlurOut").attr("result","feBlendOut").attr("mode","screen");
//***Filters***
//***Markers***
d3.select("#ExtraS").append("defs:marker").attr("id","markerTriangle").attr("markerWidth",6).attr("markerHeight",6).attr("refX",1).attr("refY",3).attr("orient","auto");
d3.select("#markerTriangle").append("marker:path").attr("d","M1,1 L4,3 L1,5 L1,1 Z").attr("fill","Orange").attr("stroke-width",2).attr("stroke","Orange").attr("stroke-linejoin","round");
//***Markers***
//***Global Variables for Graphpad
var GoldenRatio = 1.618;
var Relocate = 0;
var MouseOut = 1;
var GraphWdefault = 2000;
var GraphHdefault = GraphWdefault/GoldenRatio;
var GraphHnew = GraphHdefault;
var GraphWnew = GraphWdefault;
var GraphNewLocation = [2000,2375];
var GraphOpen = "no";
var GraphWindowSize = 50;
var GraphData = [];
//***Global Variables for Graphpad
var cdna = ["A","T","G","T","C","A","A","G","C","T","C","T","T","C","C","T","G","G","C","T","C","C","T","T","C","T","C","A","G","C","C","T","T","G","T","T","G","C","T","G","T","A","A","C","T","G","C","T","G","C","T","C","A","G","T","C","C","A","C","C","A","T","T","G","A","G","G","A","A","C","A","G","G","C","C","A","A","G","A","C","A","T","T","T","T","T","G","G","A","C","A","A","G","T","T","T","A","A","C","C",
"A","C","G","A","A","G","C","C","G","A","A","G","A","C","C","T","G","T","T","C","T","A","T","C","A","A","A","G","T","T","C","A","C","T","T","G","C","T","T","C","T","T","G","G","A","A","T","T","A","T","A","A","C","A","C","C","A","A","T","A","T","T","A","C","T","G","A","A","G","A","G","A","A","T","G","T","C","C","A","A","A","A","C","A","T","G","A","A","T","A","A","T","G","C","T","G","G","G","G","A",
"C","A","A","A","T","G","G","T","C","T","G","C","C","T","T","T","T","T","A","A","A","G","G","A","A","C","A","G","T","C","C","A","C","A","C","T","T","G","C","C","C","A","A","A","T","G","T","A","T","C","C","A","C","T","A","C","A","A","G","A","A","A","T","T","C","A","G","A","A","T","C","T","C","A","C","A","G","T","C","A","A","G","C","T","T","C","A","G","C","T","G","C","A","G","G","C","T","C","T","T",
"C","A","G","C","A","A","A","A","T","G","G","G","T","C","T","T","C","A","G","T","G","C","T","C","T","C","A","G","A","A","G","A","C","A","A","G","A","G","C","A","A","A","C","G","G","T","T","G","A","A","C","A","C","A","A","T","T","C","T","A","A","A","T","A","C","A","A","T","G","A","G","C","A","C","C","A","T","C","T","A","C","A","G","T","A","C","T","G","G","A","A","A","A","G","T","T","T","G","T","A",
"A","C","C","C","A","G","A","T","A","A","T","C","C","A","C","A","A","G","A","A","T","G","C","T","T","A","T","T","A","C","T","T","G","A","A","C","C","A","G","G","T","T","T","G","A","A","T","G","A","A","A","T","A","A","T","G","G","C","A","A","A","C","A","G","T","T","T","A","G","A","C","T","A","C","A","A","T","G","A","G","A","G","G","C","T","C","T","G","G","G","C","T","T","G","G","G","A","A","A","G",
"C","T","G","G","A","G","A","T","C","T","G","A","G","G","T","C","G","G","C","A","A","G","C","A","G","C","T","G","A","G","G","C","C","A","T","T","A","T","A","T","G","A","A","G","A","G","T","A","T","G","T","G","G","T","C","T","T","G","A","A","A","A","A","T","G","A","G","A","T","G","G","C","A","A","G","A","G","C","A","A","A","T","C","A","T","T","A","T","G","A","G","G","A","C","T","A","T","G","G","G",
"G","A","T","T","A","T","T","G","G","A","G","A","G","G","A","G","A","C","T","A","T","G","A","A","G","T","A","A","A","T","G","G","G","G","T","A","G","A","T","G","G","C","T","A","T","G","A","C","T","A","C","A","G","C","C","G","C","G","G","C","C","A","G","T","T","G","A","T","T","G","A","A","G","A","T","G","T","G","G","A","A","C","A","T","A","C","C","T","T","T","G","A","A","G","A","G","A","T","T","A",
"A","A","C","C","A","T","T","A","T","A","T","G","A","A","C","A","T","C","T","T","C","A","T","G","C","C","T","A","T","G","T","G","A","G","G","G","C","A","A","A","G","T","T","G","A","T","G","A","A","T","G","C","C","T","A","T","C","C","T","T","C","C","T","A","T","A","T","C","A","G","T","C","C","A","A","T","T","G","G","A","T","G","C","C","T","C","C","C","T","G","C","T","C","A","T","T","T","G","C","T",
"T","G","G","T","G","A","T","A","T","G","T","G","G","G","G","T","A","G","A","T","T","T","T","G","G","A","C","A","A","A","T","C","T","G","T","A","C","T","C","T","T","T","G","A","C","A","G","T","T","C","C","C","T","T","T","G","G","A","C","A","G","A","A","A","C","C","A","A","A","C","A","T","A","G","A","T","G","T","T","A","C","T","G","A","T","G","C","A","A","T","G","G","T","G","G","A","C","C","A","G",
"G","C","C","T","G","G","G","A","T","G","C","A","C","A","G","A","G","A","A","T","A","T","T","C","A","A","G","G","A","G","G","C","C","G","A","G","A","A","G","T","T","C","T","T","T","G","T","A","T","C","T","G","T","T","G","G","T","C","T","T","C","C","T","A","A","T","A","T","G","A","C","T","C","A","A","G","G","A","T","T","C","T","G","G","G","A","A","A","A","T","T","C","C","A","T","G","C","T","A","A",
"C","G","G","A","C","C","C","A","G","G","A","A","A","T","G","T","T","C","A","G","A","A","A","G","C","A","G","T","C","T","G","C","C","A","T","C","C","C","A","C","A","G","C","T","T","G","G","G","A","C","C","T","G","G","G","G","A","A","G","G","G","C","G","A","C","T","T","C","A","G","G","A","T","C","C","T","T","A","T","G","T","G","C","A","C","A","A","A","G","G","T","G","A","C","A","A","T","G","G","A",
"C","G","A","C","T","T","C","C","T","G","A","C","A","G","C","T","C","A","T","C","A","T","G","A","G","A","T","G","G","G","G","C","A","T","A","T","C","C","A","G","T","A","T","G","A","T","A","T","G","G","C","A","T","A","T","G","C","T","G","C","A","C","A","A","C","C","T","T","T","T","C","T","G","C","T","A","A","G","A","A","A","T","G","G","A","G","C","T","A","A","T","G","A","A","G","G","A","T","T","C",
"C","A","T","G","A","A","G","C","T","G","T","T","G","G","G","G","A","A","A","T","C","A","T","G","T","C","A","C","T","T","T","C","T","G","C","A","G","C","C","A","C","A","C","C","T","A","A","G","C","A","T","T","T","A","A","A","A","T","C","C","A","T","T","G","G","T","C","T","T","C","T","G","T","C","A","C","C","C","G","A","T","T","T","T","C","A","A","G","A","A","G","A","C","A","A","T","G","A","A","A",
"C","A","G","A","A","A","T","A","A","A","C","T","T","C","C","T","G","C","T","C","A","A","A","C","A","A","G","C","A","C","T","C","A","C","G","A","T","T","G","T","T","G","G","G","A","C","T","C","T","G","C","C","A","T","T","T","A","C","T","T","A","C","A","T","G","T","T","A","G","A","G","A","A","G","T","G","G","A","G","G","T","G","G","A","T","G","G","T","C","T","T","T","A","A","A","G","G","G","G","A",
"A","A","T","T","C","C","C","A","A","A","G","A","C","C","A","G","T","G","G","A","T","G","A","A","A","A","A","G","T","G","G","T","G","G","G","A","G","A","T","G","A","A","G","C","G","A","G","A","G","A","T","A","G","T","T","G","G","G","G","T","G","G","T","G","G","A","A","C","C","T","G","T","G","C","C","C","C","A","T","G","A","T","G","A","A","A","C","A","T","A","C","T","G","T","G","A","C","C","C","C",
"G","C","A","T","C","T","C","T","G","T","T","C","C","A","T","G","T","T","T","C","T","A","A","T","G","A","T","T","A","C","T","C","A","T","T","C","A","T","T","C","G","A","T","A","T","T","A","C","A","C","A","A","G","G","A","C","C","C","T","T","T","A","C","C","A","A","T","T","C","C","A","G","T","T","T","C","A","A","G","A","A","G","C","A","C","T","T","T","G","T","C","A","A","G","C","A","G","C","T","A",
"A","A","C","A","T","G","A","A","G","G","C","C","C","T","C","T","G","C","A","C","A","A","A","T","G","T","G","A","C","A","T","C","T","C","A","A","A","C","T","C","T","A","C","A","G","A","A","G","C","T","G","G","A","C","A","G","A","A","A","C","T","G","T","T","C","A","A","T","A","T","G","C","T","G","A","G","G","C","T","T","G","G","A","A","A","A","T","C","A","G","A","A","C","C","C","T","G","G","A","C",
"C","C","T","A","G","C","A","T","T","G","G","A","A","A","A","T","G","T","T","G","T","A","G","G","A","G","C","A","A","A","G","A","A","C","A","T","G","A","A","T","G","T","A","A","G","G","C","C","A","C","T","G","C","T","C","A","A","C","T","A","C","T","T","T","G","A","G","C","C","C","T","T","A","T","T","T","A","C","C","T","G","G","C","T","G","A","A","A","G","A","C","C","A","G","A","A","C","A","A","G",
"A","A","T","T","C","T","T","T","T","G","T","G","G","G","A","T","G","G","A","G","T","A","C","C","G","A","C","T","G","G","A","G","T","C","C","A","T","A","T","G","C","A","G","A","C","C","A","A","A","G","C","A","T","C","A","A","A","G","T","G","A","G","G","A","T","A","A","G","C","C","T","A","A","A","A","T","C","A","G","C","T","C","T","T","G","G","A","G","A","T","A","A","A","G","C","A","T","A","T","G",
"A","A","T","G","G","A","A","C","G","A","C","A","A","T","G","A","A","A","T","G","T","A","C","C","T","G","T","T","C","C","G","A","T","C","A","T","C","T","G","T","T","G","C","A","T","A","T","G","C","T","A","T","G","A","G","G","C","A","G","T","A","C","T","T","T","T","T","A","A","A","A","G","T","A","A","A","A","A","A","T","C","A","G","A","T","G","A","T","T","C","T","T","T","T","T","G","G","G","G","A",
"G","G","A","G","G","A","T","G","T","G","C","G","A","G","T","G","G","C","T","A","A","T","T","T","G","A","A","A","C","C","A","A","G","A","A","T","C","T","C","C","T","T","T","A","A","T","T","T","C","T","T","T","G","T","C","A","C","T","G","C","A","C","C","T","A","A","A","A","A","T","G","T","G","T","C","T","G","A","T","A","T","C","A","T","T","C","C","T","A","G","A","A","C","T","G","A","A","G","T","T",
"G","A","A","A","A","G","G","C","C","A","T","C","A","G","G","A","T","G","T","C","C","C","G","G","A","G","C","C","G","T","A","T","C","A","A","T","G","A","T","G","C","T","T","T","C","C","G","T","C","T","G","A","A","T","G","A","C","A","A","C","A","G","C","C","T","A","G","A","G","T","T","T","C","T","G","G","G","G","A","T","A","C","A","G","C","C","A","A","C","A","C","T","T","G","G","A","C","C","T","C",
"C","T","A","A","C","C","A","G","C","C","C","C","C","T","G","T","T","T","C","C","A","T","A","T","G","G","C","T","G","A","T","T","G","T","T","T","T","T","G","G","A","G","T","T","G","T","G","A","T","G","G","G","A","G","T","G","A","T","A","G","T","G","G","T","T","G","G","C","A","T","T","G","T","C","A","T","C","C","T","G","A","T","C","T","T","C","A","C","T","G","G","G","A","T","C","A","G","A","G","A",
"T","C","G","G","A","A","G","A","A","G","A","A","A","A","A","T","A","A","A","G","C","A","A","G","A","A","G","T","G","G","A","G","A","A","A","A","T","C","C","T","T","A","T","G","C","C","T","C","C","A","T","C","G","A","T","A","T","T","A","G","C","A","A","A","G","G","A","G","A","A","A","A","T","A","A","T","C","C","A","G","G","A","T","T","C","C","A","A","A","A","C","A","C","T","G","A","T","G","A","T",
"G","T","T","C","A","G","A","C","C","T","C","C","T","T","T"];
var aminoacids_degenerateCode = {"A":["GCT","GCC","GCA","GCG"], "R":["CGT","CGC","CGA","CGG","AGA","AGG"], "N":["AAT","AAC"], "D":["GAT","GAC"], "C":["TGT","TGC"], "Q":["CAA","CAG"], "E":["GAA","GAG"], "G":["GGT","GGC","GGA","GGG"], "H":["CAT","CAC"], "I":["ATT","ATC","ATA"], "L":["TTA","TTG","CTT","CTC","CTA","CTG"], "K":["AAA","AAG"], "M":["ATG"], "F":["TTT","TTC"], "P":["CCT","CCC","CCA","CCG"], "S":["TCT","TCC","TCA","TCG","AGT","AGC"], "T":["ACT","ACC","ACA","ACG"], "W":["TGG"], "Y":["TAT","TAC"], "V":["GTT","GTC","GTA","GTG"], "X":["TAA","TGA","TAG"]};
var fasta = [];
var fasta_sorted = [];
var aminoacids = {"A":["Alanine","Nonpolar"],"R":["Arginine","Positive"],"N":["Asparagine","Polar"],"D":["Aspartic-Acid","Negative"],"C":["Cysteine","Polar"],"Q":["Glutamine","Polar"],"E":["Glutamic-Acid","Negative"],"G":["Glycine","Nonpolar"],"H":["Histidine","Positive"],"I":["Isoleucine","Nonpolar"],"L":["Leucine","Nonpolar"],"K":["Lysine","Positive"],"M":["Methionine","Nonpolar"],"F":["Phenylalanine","Aromatic"],"P":["Proline","Nonpolar"],"S":["Serine","Polar"],"T":["Threonine","Polar"],"W":["Tryptophan","Aromatic"],"Y":["Tyrosine","Aromatic"],"V":["Valine","Nonpolar"]};
var aminoacids_OtherProperties = {"A":["Hydrophobic","Aliphatic"],"R":["Hydrophilic","H-bonding","Basic","Ionizable"],"N":["Hydrophilic"],"D":["Hydrophilic","H-bonding","Acidic","Ionizable"],"C":["Hydrophilic","H-bonding","Sulfur-containing","Acidic","Ionizable","Disulfide-bond"],"Q":["Hydrophilic","H-bonding"],"E":["Hydrophilic","H-bonding","Acidic","Ionizable"],"G":["Hydrophobic","Aliphatic"],"H":["Hydrophilic","H-bonding","Basic","Ionizable","All-aromatic"],"I":["Hydrophobic","Aliphatic"],"L":["Hydrophobic","Aliphatic"],"K":["Hydrophilic","H-bonding","Basic","Ionizable"],"M":["Hydrophobic","Sulfur-containing"],"F":["Hydrophobic","All-aromatic"],"P":["Hydrophobic","Aliphatic","Cyclic"],"S":["Hydrophilic","H-bonding"],"T":["Hydrophilic","H-bonding"],"W":["Hydrophobic","H-bonding","All-aromatic"],"Y":["Hydrophobic","H-bonding","Ionizable","All-aromatic"],"V":["Hydrophobic","Aliphatic"]};
var screen_aspect = 16/9;
var R_Click = 0;
var coordinates = [0,0];
var coordinates_time = [];
d3.select("#master")
.attr("onmouseup",function(){return "enlargeEndMU(evt)"})
.on("mousemove", function(){
coordinates = d3.mouse(this);
if (R_Click == 1) {
if (coordinates_time.length >= 4) {
coordinates_time.shift();
coordinates_time.shift();
coordinates_time.push(coordinates[0]);
coordinates_time.push(coordinates[1]);
} else {
coordinates_time.push(coordinates[0]);
coordinates_time.push(coordinates[1]);
}
var distance = Math.sqrt(Math.pow((coordinates_time[2]-coordinates_time[0]),2)+Math.pow((coordinates_time[3]-coordinates_time[1]),2));
var distance_origin = Math.sqrt(Math.pow((coordinates[0]-3000),2)+Math.pow((coordinates[1]-3000),2));
var sensitivity = 0.01;
var radius_max = 3000*Math.sqrt(2);
var factorX = 0.2+0.5*Math.pow((distance_origin/radius_max),2);
var factorY = screen_aspect*factorX;
var Xdiff = (coordinates_time[2]-coordinates_time[0]);
var Ydiff = (coordinates_time[3]-coordinates_time[1]);
var sine = Math.abs(Ydiff/Math.sqrt(Math.pow(Xdiff,2)+Math.pow(Ydiff,2)));
var cosine = Math.abs(Xdiff/Math.sqrt(Math.pow(Xdiff,2)+Math.pow(Ydiff,2)));
var constantX = factorX*Math.pow(cosine,4/7);
var constantY = factorY*Math.pow(sine,4/7);
var Xpos = constantX*Xdiff;
var Ypos = constantY*Ydiff;
if (distance >= sensitivity) {
window.scrollBy(Xpos/4,Ypos/4);
}
}
})
.on("contextmenu", function (){
d3.select("#rightclick1").remove();
d3.select("#rightclick2").remove();
if (R_Click == 0) {
R_Click = 1;
} else {
R_Click = 0;
//hide or show overview tabs to prevent overlap
hideOrshowhtmlElements("1",true);
}
if (R_Click == 1) {
d3.select("#annotation").append("text").text("Use the outer region to scroll.").attr("id","rightclick1").attr("text-anchor","middle").attr("x", 3000).attr("y", 3200).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("Right-click to cancel autoscroll.").attr("id","rightclick2").attr("text-anchor","middle").attr("x", 3000).attr("y", 3000).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#rightclick1").transition().attr("fill-opacity",0.9).delay(500).duration(500);
d3.select("#rightclick2").transition().attr("fill-opacity",0.9).delay(500).duration(500);
//hide or show overview tabs to prevent overlap
hideOrshowhtmlElements("0",true);
}
})
.on("click", function () {
if ((Relocate == 1)&&(MouseOut == 1)) {
d3.select("#GraphSvg").transition().attr("x",function () {return coordinates[0]-50;}).attr("y",function () {return coordinates[1]-50;}).delay(0).duration(500);
GraphNewLocation = [];
GraphNewLocation.push(coordinates[0]-50);
GraphNewLocation.push(coordinates[1]-50);
Relocate = 0;
}
if (relocateWindow !== "") {
d3.select(relocateWindow).transition().attr("x",function(){return coordinates[0]-50;}).attr("y",function(){return coordinates[1]-50;}).delay(0).duration(500);
relocateWindow = "";
}
});
//***Tile and SNV databases***
//default = "dbSNP","ClinVar","HGMD"
var TileDB = ["All","None","dbSNP","ClinVar","HGMD","substitution","deletion","insertion","frameshift"];
var MutDB = ["All","Stop","Synonymous","Nonsynonymous","pXtoY","None","dbSNP","ClinVar","HGMD"];
//***Tile and SNV databases***
var list_seq = d3.select(document.body).select("#master").selectAll(".sequence");
var list_scat = d3.select(document.body).select("#master").selectAll(".scatter");
var list_con = d3.select(document.body).select("#master").select("#plot0").selectAll("*");
var domainList = ["All","Coil"];
var list_mut = d3.select(document.body).select("#master").selectAll(".mut");
var list_connector = d3.select(document.body).select("#master").selectAll(".connector");
var list_tile = d3.select(document.body).select("#master").selectAll(".tile");
var ids = {"seq":[],"scat":[],"con":[],"mut":[],"connector":[],"tile":[]};
for (var i = 0;i<list_seq[0].length;i++) {
var individual_id = d3.select(list_seq[0][i]).attr("id");
ids["seq"].push("#"+individual_id);
}
for (var i = 0;i<list_scat[0].length;i++) {
var individual_id = d3.select(list_scat[0][i]).attr("id");
ids["scat"].push("#"+individual_id);
}
(function () {for (var i = 1;i<list_con[0].length;i++) {
var individual_id = d3.select(list_con[0][i]).attr("id");
ids["con"].push("#"+individual_id);
if(d3.select("#"+individual_id).attr("class") !== null && d3.select("#"+individual_id).attr("class") !== undefined) {
var clss = d3.select("#"+individual_id).attr("class");
if (!(domainList.some(function(d){return d===clss}))) {
domainList.push(clss);
}
clss = clss+" allCons";
d3.select("#"+individual_id).attr("class",clss);
} else {
d3.select("#"+individual_id).attr("class","allCons");
}
}})();
for (var i = 0;i<list_mut[0].length;i++) {
var individual_id = d3.select(list_mut[0][i]).attr("id");
ids["mut"].push("#"+individual_id);
var database_source = d3.select(list_mut[0][i]).attr("dbsource");
var regexp = new RegExp(database_source,"i");
if ((MutDB.some(function(x){return x.match(regexp);})) || MutDB.length >= 20){
} else {
MutDB.push(database_source);
}
}
for (var i = 0;i<list_connector[0].length;i++) {
var individual_id = d3.select(list_connector[0][i]).attr("id");
ids["connector"].push("#"+individual_id);
}
//Original Tile Properties
var Or_Tile_Stroke_Color = [];
var Or_Tile_Stroke_Width = [];
var Or_Tile_Coordinates = [];
var Or_Tile_FrameCharacter = [];
var Or_Tile_Fill_Color = [];
//Original Tile Properties
for (var i = 0;i<list_tile[0].length;i++) {
var individual_id = d3.select(list_tile[0][i]).attr("id");
var stroke_color = d3.select(list_tile[0][i]).style("stroke");
if (stroke_color == null | stroke_color === 'undefined') {
stroke_color = d3.select(list_tile[0][i]).style("fill");
}
var stroke_width = d3.select(list_tile[0][i]).style("stroke-width");
if (stroke_width == null | stroke_color === 'undefined') {
stroke_width = 0;
}
ids["tile"].push("#"+individual_id);
Or_Tile_Stroke_Color.push(stroke_color);
Or_Tile_Stroke_Width.push(stroke_width);
var TileHash = {};
var TilePathElements = d3.select(ids["tile"][i]).attr("d").split(/[MLAZ,]|\s+/);
TileHash["TopLeftCornerx"] = TilePathElements[20];
TileHash["TopLeftCornery"] = TilePathElements[21];
TileHash["TopRightCornerx"] = TilePathElements[12];
TileHash["TopRightCornery"] = TilePathElements[13];
Or_Tile_Coordinates.push(TileHash);
var frameshift;
if (individual_id.match(/frameshift/)) {
frameshift = " with frameshift";
} else {
frameshift = "";
}
Or_Tile_FrameCharacter.push(frameshift);
Or_Tile_Fill_Color.push(d3.select(list_tile[0][i]).style("fill"));
var database_source = d3.select(ids["tile"][i]).attr("dbsource");
var regexp = new RegExp(database_source,"i");
if ((TileDB.some(function(x){return x.match(regexp);})) || TileDB.length >= 20){
} else {
TileDB.push(database_source);
}
}
//***Fasta***
for (var i = 0;i<list_seq[0].length;i++) {
var individual_id = d3.select(list_seq[0][i]).attr("id");
fasta.push(individual_id);
}
for (var i = 0;i<fasta.length;i++) {
fasta[i] = fasta[i].replace(/^seq_/,"");
fasta[i] = fasta[i].split("_");
}
for (var i = 0;i<fasta.length;i++) {
for (var j = 0;j<fasta.length;j++) {
if (fasta[j][1]==i+1) {
fasta_sorted.push(fasta[j]);
}
}
}
for (var i = 0;i<fasta_sorted.length;i++) {
fasta_sorted[i] = fasta_sorted[i][0];
for (var j in aminoacids) {
if (aminoacids[j][0] == fasta_sorted[i])
fasta_sorted[i] = j;
}
}
//***Fasta***
//***Original Radial Positioning of Conservation Elements***
var HalfTheWidthAngleOfElement = 355/(2*fasta_sorted.length);
//***There is a linearly increasing angle mistake that is maximized towards the end to approximately 1 degrees.
//***I calibrated this using CALR and BRCA1 and seems to work well. Some elements in the formula below is redundant however I will keep it explicit.
var CorrectionFactor = 1.25*fasta_sorted.length/417*HalfTheWidthAngleOfElement/fasta_sorted.length;
//***Original Radial Positioning of Conservation Elements***
//***Original Properties of Drawing elements***
var Or_Seq_Font_Size = d3.select(ids["seq"][0]).attr("font-size");
var Or_Scat_Stroke_Width = d3.select(ids["scat"][0]).attr("stroke-width");
var Or_Scat_Stroke_Color = d3.select(ids["scat"][0]).attr("stroke");
var Or_Scat_Size = 45;
var Or_Con_Stroke_Width = d3.select(ids["con"][0]).style("stroke-width");
var Or_Con_Stroke_Color = [];
(function (){
for (var i = 0;i<ids["con"].length;i++) {
Or_Con_Stroke_Color.push(d3.select(ids["con"][i]).style("stroke"));
}
})();
var Or_Con_Fill_Color = [];
(function (){
for (var i = 0;i<ids["con"].length;i++) {
Or_Con_Fill_Color.push(d3.select(ids["con"][i]).style("fill"));
}
})();
var Or_Mut_Font_Size = d3.select(ids["mut"][0]).attr("font-size");
var Or_Mut_Fill_Color = [];
(function (){
for (var i = 0;i<ids["mut"].length;i++) {
Or_Mut_Fill_Color.push(d3.select(ids["mut"][i]).style("fill"));
}
})();
var Or_Connector_Font_Size = d3.select(ids["connector"][0]).attr("font-size");
//***Original Properties of Drawing elements***
window.code = "";
var w = 6000;
var h = 6000;
var padding = 200;
d3.select("body").style("background-color", "white");
//***Options Control***
var optionStatus = "open";
d3.select("#annotation").append("text").text("Hide Options").attr("id","HideOptions").attr("text-anchor","middle").attr("x", 200).attr("y", 200).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#HideOptions")
.on("mouseover",function() {
d3.select("#HideOptions").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#HideOptions").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
d3.selectAll(".Options").transition().attr("fill-opacity",0.0).delay(0).duration(500);
d3.selectAll(".Options_Circle").data(function () {return d3.keys(aminoacids);}).each(function(d,i) {d3.select("#AminoacidsChoiceCircle_"+String(d)).transition().attr("stroke-opacity",function(d,i) {if (aminoacids[d][2]=="Clicked"){return 0.0;}else{return 0.0}}).delay(0).duration(500);});
d3.select("#LHlight").transition().attr("stroke-opacity",0.0).delay(0).duration(500);
//d3.select("#LEbulb").transition().attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#RHlight").transition().attr("stroke-opacity",0.0).delay(0).duration(500);
//d3.select("#REbulb").transition().attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#LHtext").transition().attr("fill-opacity",0.0).attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#RHtext").transition().attr("fill-opacity",0.0).attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#LHtext2").transition().attr("fill-opacity",0.0).attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#RHtext2").transition().attr("fill-opacity",0.0).attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#LIbulb").transition().attr("stroke-opacity",0.0).delay(0).duration(500);
d3.select("#RIbulb").transition().attr("stroke-opacity",0.0).delay(0).duration(500);
d3.selectAll(".DropDownRect").transition().attr("fill-opacity",0.0).delay(0).duration(500);
d3.selectAll(".DropDownText").transition().attr("fill-opacity",0.0).delay(0).duration(500);
d3.selectAll(".DropDownRectSnv").transition().attr("fill-opacity",0.0).delay(0).duration(500);
d3.selectAll(".DropDownTextSnv").transition().attr("fill-opacity",0.0).delay(0).duration(500);
d3.selectAll(".DropDownRectTile").transition().attr("fill-opacity",0.0).delay(0).duration(500);
d3.selectAll(".DropDownTextTile").transition().attr("fill-opacity",0.0).delay(0).duration(500);
//d3.selectAll(".DropDownRectExtract").transition().attr("fill-opacity",0.0).delay(0).duration(500);-->passed to hideOrshow function..
d3.select("#HideOptions").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#ShowOptions").transition().attr("visibility","visible").delay(0).duration(0);
//#ipvWatchIcon
d3.select("#ipvWatchIcon").style("opacity",0).style("visibility","hidden");
//#ipvWatchIcon
//#colorCoding
d3.select("#colorCoding").style("opacity",0).style("visibility","hidden");
//#colorCoding
//#neonEffect
d3.select("#neonEffect").style("opacity",0).style("visibility","hidden");
//#neonEffect
//#htmlElements and Input boxes
hideOrshowhtmlElements("0",false,false,true);
//#htmlElements and Input boxes
//overview tabs
d3.selectAll(".overviews").style("opacity",0).style("visibility","hidden");
//overview tabs
//Update option status
optionStatus = "closed";
//Update option status
//File Upload Elements
d3.selectAll(".actionOptions").transition().attr("fill-opacity",0.0).attr("visibility","hidden").delay(0).duration(500);
d3.select("#fileUploadIcon").style("opacity",0).attr("visibility","hidden");
//File Upload Elements
//IndorilLogo
d3.selectAll(".indorilLogo").style("opacity",0).style("visibility","hidden");
//IndorilLogo
});
d3.select("#annotation").append("text").text("Show Options").attr("id","ShowOptions").attr("text-anchor","middle").attr("x", 200).attr("y", 200).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","hidden");
d3.select("#ShowOptions")
.on("mouseover",function() {
d3.select("#ShowOptions").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#ShowOptions").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
d3.selectAll(".Options").transition().attr("fill-opacity", 0.9).delay(0).duration(500);
d3.selectAll(".Options_Circle").data(function () {return d3.keys(aminoacids);}).each(function(d,i) {d3.select("#AminoacidsChoiceCircle_"+String(d)).transition().attr("stroke-opacity",function(d,i) {if (aminoacids[d][2]=="Clicked"){return 0.9;}else{return 0.0}}).delay(0).duration(500);});
d3.select("#LHlight").transition().attr("stroke-opacity",0.5).delay(0).duration(500);
//d3.select("#LEbulb").transition().attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#RHlight").transition().attr("stroke-opacity",0.5).delay(0).duration(500);
//d3.select("#REbulb").transition().attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#LHtext").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#RHtext").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#LHtext2").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#RHtext2").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#LIbulb").transition().attr("stroke-opacity",0.5).delay(0).duration(500);
d3.select("#RIbulb").transition().attr("stroke-opacity",0.5).delay(0).duration(500);
d3.selectAll(".DropDownRect").transition().attr("fill-opacity",0.9).delay(0).duration(500);
d3.selectAll(".DropDownText").transition().attr("fill-opacity",0.9).delay(0).duration(500);
d3.selectAll(".DropDownRectSnv").transition().attr("fill-opacity",0.9).delay(0).duration(500);
d3.selectAll(".DropDownTextSnv").transition().attr("fill-opacity",0.9).delay(0).duration(500);
d3.selectAll(".DropDownRectTile").transition().attr("fill-opacity",0.9).delay(0).duration(500);
d3.selectAll(".DropDownTextTile").transition().attr("fill-opacity",0.9).delay(0).duration(500);
//d3.selectAll(".DropDownRectExtract").transition().attr("fill-opacity",0.9).delay(0).duration(500);-->passed to hideOrshow function..
d3.select("#ShowOptions").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#HideOptions").transition().attr("visibility","visible").delay(0).duration(0);
//#ipvWatchIcon
d3.select("#ipvWatchIcon").style("opacity",0.62).style("visibility","visible");
//#ipvWatchIcon
//#colorCoding
d3.select("#colorCoding").style("opacity",1.0).style("visibility","visible");
//#colorCoding
//#neonEffect
d3.select("#neonEffect").style("opacity",1.0).style("visibility","visible");
//#neonEffect
//#htmlElements and Input boxes
hideOrshowhtmlElements("1",false,false,true);
//#htmlElements and Input boxes
//overview tabs
d3.selectAll(".overviews").style("opacity",1.0).style("visibility","visible");
//overview tabs
//Update option status
optionStatus = "open";
//Update option status
//File Upload Elements
d3.selectAll(".actionOptions").transition().attr("fill-opacity",0.9).attr("visibility","visible").delay(0).duration(500);
d3.select("#fileUploadIcon").style("opacity",0.62).attr("visibility","visible");
//File Upload Elements
//IndorilLogo
d3.selectAll(".indorilLogo").style("opacity",1.0).style("visibility","visible");
//IndorilLogo
});
//***Options Control***
//***background***
d3.select("#annotation").append("text").text("background:black").attr("class","Options").attr("id","backgroundblack").attr("text-anchor","middle").attr("x", 3000).attr("y", 2000).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("background:white").attr("class","Options").attr("id","backgroundwhite").attr("text-anchor","middle").attr("x", 3000).attr("y", 2000).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","hidden");
d3.select("#backgroundblack").on("mouseover", function (){
d3.select("#backgroundblack").transition().attr("fill","Orange").delay(0).duration(100);
})
.on("mouseout", function(){
d3.select("#backgroundblack").transition().attr("fill","DimGray").delay(0).duration(100);
})
.on("click", function (){
d3.select("#backgroundblack").transition("backgroundControlChangeFadeout").attr("visibility","hidden").delay(0).duration(100);
d3.select("body").transition("backgroundBodyChange").style("background-color", "black").delay(100).duration(100);
d3.select("html").transition("backgroundHtmlChange").style("background-color", "black").delay(100).duration(100);
d3.select("#backgroundwhite").transition("backgroundControlChangeFadein").attr("visibility","visible").delay(200).duration(100);
d3.selectAll(".Options_Lights").transition("backgroundLightsChange").attr("fill","DodgerBlue").attr("stroke","DodgerBlue").delay(300).duration(250);
//Html Input Background
d3.selectAll(".htmlElementsInputs").style("background","rgba(30,144,255,0.4)");
//Html Input Background
});
d3.select("#backgroundwhite").on("mouseover", function (){
d3.select("#backgroundwhite").transition().attr("fill","Orange").delay(0).duration(100);
})
.on("mouseout", function(){
d3.select("#backgroundwhite").transition().attr("fill","DimGray").delay(0).duration(100);
})
.on("click", function (){
d3.select("#backgroundwhite").transition("backgroundControlChangeFadeout").attr("visibility","hidden").delay(0).duration(100);
d3.select("body").transition("backgroundBodyChange").style("background-color", "white").delay(100).duration(100);
d3.select("html").transition("backgroundHtmlChange").style("background-color", "white").delay(100).duration(100);
d3.select("#backgroundblack").transition("backgroundControlChangeFadein").attr("visibility","visible").delay(200).duration(100);
d3.selectAll(".Options_Lights").transition("backgroundLightsChange").attr("fill","Orange").attr("stroke","Orange").delay(300).duration(250);
//Html Input Background
d3.selectAll(".htmlElementsInputs").style("background","rgba(255,165,0,0.4)");
//Html Input Background
});
//***background***
//***Aminoacid Properties***
var AminoAcidProperties = ["Nonpolar","Polar","Positive","Negative","Aromatic","All-aromatic","Aliphatic","Cyclic","Hydrophobic","Hydrophilic","Acidic","Basic","Ionizable","H-bonding","Disulfide-bond","Sulfur-containing","All","None","Sequence Display"];
var AminoAcidPropertiesCount = 16;
var DropDownClick = 0;
var WhatsClicked = [];
d3.select("#annotation").append("text").text(function() {return AminoAcidProperties[AminoAcidPropertiesCount];}).attr("class","Options").attr("id","PropChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2275).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible")//.transition().attr("fill-opacity",0.9).delay(0).duration(750)
.on("click",function() {
if (DropDownClick == 0) {
d3.select("#annotation").call(DropDown);
} else {
d3.selectAll(".DropDownRect").remove();
d3.selectAll(".DropDownText").remove();
}
if (DropDownClick == 0) {
DropDownClick = 1;
} else {
DropDownClick = 0;
}
});
d3.select("#PropChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.select("#annotation").append("path").attr("d","M 2700,2200 L 2675,2250 L 2700,2300 Z").attr("class","Options").attr("id","Ltriangle").attr("fill","DimGray").attr("fill-opacity", 0.8)
.on("mouseover",function() {
d3.select("#Ltriangle").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#Ltriangle").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
if (AminoAcidPropertiesCount == 0) {
AminoAcidPropertiesCount = 18;
} else {
AminoAcidPropertiesCount = AminoAcidPropertiesCount - 1;
}
d3.select("#PropChoice").remove();
d3.select("#annotation").append("text").text(function(){return AminoAcidProperties[AminoAcidPropertiesCount];}).attr("class","Options").attr("id","PropChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2275).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("click",function() {
if (DropDownClick == 0) {
d3.select("#annotation").call(DropDown);
} else {
d3.selectAll(".DropDownRect").remove();
d3.selectAll(".DropDownText").remove();
}
if (DropDownClick == 0) {
DropDownClick = 1;
} else {
DropDownClick = 0;
}
});
d3.select("#PropChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.selectAll(".scatter").data(ids["scat"]).each(function(d,i) {var ResidueNumber = d.replace(/^.*scat_.*_/,"");d3.select(d).transition().attr("fill-opacity",function (){var aminoacid = fasta_sorted[ResidueNumber-1];if(AminoAcidProperties[AminoAcidPropertiesCount] == "All" || d.match(AminoAcidProperties[AminoAcidPropertiesCount]) || aminoacids_OtherProperties[fasta_sorted[ResidueNumber-1]].some(function(x){return x.match(AminoAcidProperties[AminoAcidPropertiesCount]);}) || (AminoAcidProperties[AminoAcidPropertiesCount] == "Sequence Display" && aminoacids[aminoacid][2] == "Clicked")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
WhatsClicked = [];
for (i=0;i<d3.keys(aminoacids).length;i++) {
if(aminoacids[d3.keys(aminoacids)[i]][2]=="Clicked") {
WhatsClicked.push(d3.keys(aminoacids)[i]);
}
}
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
});
d3.select("#annotation").append("path").attr("d","M 3300,2200 L 3325,2250 L 3300,2300 Z").attr("class","Options").attr("id","Rtriangle").attr("fill","DimGray").attr("fill-opacity", 0.8)
.on("mouseover",function() {
d3.select("#Rtriangle").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#Rtriangle").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
if (AminoAcidPropertiesCount == 18) {
AminoAcidPropertiesCount = 0;
} else {
AminoAcidPropertiesCount = AminoAcidPropertiesCount + 1;
}
d3.select("#PropChoice").remove();
d3.select("#annotation").append("text").text(function(){return AminoAcidProperties[AminoAcidPropertiesCount];}).attr("class","Options").attr("id","PropChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2275).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("click",function() {
if (DropDownClick == 0) {
d3.select("#annotation").call(DropDown);
} else {
d3.selectAll(".DropDownRect").remove();
d3.selectAll(".DropDownText").remove();
}
if (DropDownClick == 0) {
DropDownClick = 1;
} else {
DropDownClick = 0;
}
});
d3.select("#PropChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.selectAll(".scatter").data(ids["scat"]).each(function(d,i) {var ResidueNumber = d.replace(/^.*scat_.*_/,"");d3.select(d).transition().attr("fill-opacity",function (){var aminoacid = fasta_sorted[ResidueNumber-1];if(AminoAcidProperties[AminoAcidPropertiesCount] == "All" || d.match(AminoAcidProperties[AminoAcidPropertiesCount]) || aminoacids_OtherProperties[fasta_sorted[ResidueNumber-1]].some(function(x){return x.match(AminoAcidProperties[AminoAcidPropertiesCount]);}) || (AminoAcidProperties[AminoAcidPropertiesCount] == "Sequence Display" && aminoacids[aminoacid][2] == "Clicked")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
WhatsClicked = [];
for (i=0;i<d3.keys(aminoacids).length;i++) {
if(aminoacids[d3.keys(aminoacids)[i]][2]=="Clicked") {
WhatsClicked.push(d3.keys(aminoacids)[i]);
}
}
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
});
//***Aminoacid Properties***
//***Aminoacid Choice
//***letters
d3.select("#annotation")
.selectAll("letters")
.data(function () {return d3.keys(aminoacids);})
.enter()
.append("text")
.text(function (d,i) {return d;})
.attr("text-anchor","middle")
.attr("x",function (d,i) {return 2400+(i%10)*133;})
.attr("y",function (d,i) {return 2550+parseInt((i+1)/11)*100;})
.attr("font-size","60px")
.attr("fill","DimGray")
.attr("stroke","DimGray")
.attr("fill-opacity",0.9)
.attr("stroke-opacity",0.0)
.attr("id",function(d,i) {return "AminoacidsChoice_"+String(d);})
.attr("class","Options");
//***letter;
//***circles***
d3.select("#annotation")
.selectAll("circles")
.data(function () {return d3.keys(aminoacids);})
.enter()
.append("circle")
.attr("r","42px")
.attr("cx",function (d,i) {return 2400+(i%10)*133;})
.attr("cy",function (d,i) {return 2525+parseInt((i+1)/11)*100;})
.attr("fill","DimGray")
.attr("stroke","DimGray")
.attr("stroke-width", "13px")
.attr("fill-opacity",0.0)
.attr("stroke-opacity",function(d,i) {if (aminoacids[d][2]=="Clicked"){return 0.9;}else{return 0.0;}})
.attr("id",function(d,i) {return "AminoacidsChoiceCircle_"+String(d);})
.attr("class","Options_Circle")
.on("mouseover",function(d,i) {
if (optionStatus === "open") {
d3.select(this).transition().attr("stroke","Orange").attr("r","100px").delay(0).duration(250);
d3.select("#AminoacidsChoice_"+String(d)).transition().attr("fill","Orange").attr("font-size","150px").delay(0).duration(250);
}
})
.on("mouseout",function(d,i) {
if (optionStatus === "open") {
d3.select(this).transition().attr("stroke",function(d,i) {if (aminoacids[d][2]=="Clicked"){return "Orange";}else{return "DimGray";}}).attr("stroke-opacity",function(d,i) {if (aminoacids[d][2]=="Clicked"){return 0.9;}else{return 0.0;}}).attr("r","42px").delay(0).duration(250);
d3.select("#AminoacidsChoice_"+String(d)).transition().attr("fill",function(d,i) {if (aminoacids[d][2]=="Clicked"){return "Orange";}else{return "DimGray";}}).attr("font-size","60px").delay(0).duration(250);
}
})
.on("click",function(d,i) {
if (optionStatus === "open") {
var LetterOfSubject = d;
d3.select(this).transition().attr("stroke",function(d,i) {if (aminoacids[d][2]=="Clicked"){return "DimGray";}else{return "Orange";}}).attr("stroke-opacity",function(d,i) {if (aminoacids[d][2]=="Clicked"){return 0.0;}else{return 0.9;}}).attr("r","42px").delay(0).duration(250);
d3.select("#AminoacidsChoice_"+String(d)).transition().attr("fill",function(d,i) {if (aminoacids[d][2]=="Clicked"){return "DimGray";}else{return "Orange";}}).attr("font-size","60px").delay(0).duration(250);
if (aminoacids[d][2]=="Clicked") {
d3.selectAll(".sequence").data(ids["seq"]).each(function(d,i) {var IdOfSubject = d3.select(d).attr("id"); if(IdOfSubject.match(aminoacids[LetterOfSubject][0])){d3.select(d).transition().attr("fill-opacity",0.0).attr("visibility","hidden").delay(0).duration(750);}});
} else {
d3.selectAll(".sequence").data(ids["seq"]).each(function(d,i) {var IdOfSubject = d3.select(d).attr("id"); if(IdOfSubject.match(aminoacids[LetterOfSubject][0])){d3.select(d).transition().attr("fill-opacity",1.0).attr("visibility","visible").delay(0).duration(750);}});
}
if (aminoacids[d][2]=="Clicked") {
aminoacids[d].pop();
} else {
aminoacids[d][2] = "Clicked";
}
}
});
//***circles***
//***Mass Selection***
d3.select("#annotation").append("path").attr("d","M 1900,2500 L 2300,2550 L 2350,2650").attr("class","Options_Lights").attr("id","LHlight").attr("fill","Orange").attr("fill-opacity", 0.0).attr("stroke","Orange").attr("stroke-opacity",0.5).attr("stroke-width","10px");
//d3.select("#annotation").append("path").attr("d","M 1920,2595, Q 1950,2620, 1980,2595").attr("class","Options_Lights").attr("id","LEbulb").attr("fill","Orange").attr("fill-opacity", 0.0).attr("stroke","Orange").attr("stroke-opacity",0.5).attr("stroke-width","10px");
d3.select("#annotation").append("path").attr("d","M 4100,2500 L 3700,2550 L 3650,2650").attr("class","Options_Lights").attr("id","RHlight").attr("fill","Orange").attr("fill-opacity", 0.0).attr("stroke","Orange").attr("stroke-opacity",0.5).attr("stroke-width","10px");
//d3.select("#annotation").append("path").attr("d","M 4080,2595, Q 4050,2620, 4020,2595").attr("class","Options_Lights").attr("id","REbulb").attr("fill","Orange").attr("fill-opacity", 0.0).attr("stroke","Orange").attr("stroke-opacity",0.5).attr("stroke-width","10px");
d3.select("#annotation").append("text").text("Clear").attr("class","Options_Lights").attr("id","LHtext").attr("text-anchor","middle").attr("x", 2000).attr("y", 2575).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.5).attr("stroke-opacity",0.5).attr("visibility","visible")
.on("mouseover",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#LHtext").transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);
d3.select("#LHlight").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").attr("filter",function() {if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)){return "url(#NeonGlow)";}else{return null;}}).delay(0).duration(750);
//d3.select("#LEbulb").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("mouseout",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#LHtext").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(750);
d3.select("#LHlight").transition().attr("stroke-opacity",0.5).attr("stroke-width","10px").attr("filter",null).delay(0).duration(750);
//d3.select("#LEbulb").transition().attr("stroke-opacity",0.5).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("click",function() {
d3.selectAll(".Options_Circle").transition().attr("stroke","DimGray").attr("stroke-opacity",0.0).attr("r","42px").delay(0).duration(250);
d3.selectAll(".sequence").transition().attr("fill-opacity",0.0).attr("visibility","hidden").delay(0).duration(750);
for (var key in aminoacids) {
d3.select("#AminoacidsChoice_"+String(key)).transition().attr("fill","DimGray").attr("font-size","60px").delay(0).duration(250);
if (aminoacids[key][2] == "Clicked") {
aminoacids[key].pop();
} else {
}
}
});
d3.select("#annotation").append("text").text("entirE").attr("class","Options_Lights").attr("id","RHtext").attr("text-anchor","middle").attr("x", 4000).attr("y", 2575).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.5).attr("stroke-opacity",0.5).attr("visibility","visible")
.on("mouseover",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#RHtext").transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);
d3.select("#RHlight").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").attr("filter",function() {if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)){return "url(#NeonGlow)";}else{return null;}}).delay(0).duration(750);
//d3.select("#REbulb").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("mouseout",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#RHtext").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(750);
d3.select("#RHlight").transition().attr("stroke-opacity",0.5).attr("stroke-width","10px").attr("filter",null).delay(0).duration(750);
//d3.select("#REbulb").transition().attr("stroke-opacity",0.5).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("click",function() {
d3.selectAll(".Options_Circle").transition().attr("stroke","Orange").attr("stroke-opacity",0.9).attr("r","42px").delay(0).duration(250);
d3.selectAll(".sequence").transition().attr("fill-opacity",1.0).attr("visibility","visible").delay(0).duration(750);
for (var key in aminoacids) {
d3.select("#AminoacidsChoice_"+String(key)).transition().attr("fill","Orange").attr("font-size","60px").delay(0).duration(250);
if (aminoacids[key][2] == "Clicked") {
} else {
aminoacids[key][2] = "Clicked";
}
}
});
//***Mass Selection***
//***Aminoacid Choice
//***FontControl***
var FontSpectrum = ["1.0x","1.5x","2x","2.5x","3x","3.5x","4.0x","4.5x","5.0x"];
var FontSpectrumCount = 0;
d3.select("#annotation").append("text").text(function() {return "Font-Size: "+String(FontSpectrum[FontSpectrumCount]);}).attr("class","Options").attr("id","FontChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2425).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.select("#annotation").append("path").attr("d","M 2600,2350 L 2575,2400 L 2600,2450 Z").attr("class","Options").attr("id","Ltriangle2").attr("fill","DimGray").attr("fill-opacity", 0.8)
.on("mouseover",function() {
d3.select("#Ltriangle2").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#Ltriangle2").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
if (FontSpectrumCount == 0) {
FontSpectrumCount = 8;
} else {
FontSpectrumCount = FontSpectrumCount - 1;
}
d3.select("#FontChoice").remove();
d3.select("#annotation").append("text").text(function() {return "Font-Size: "+String(FontSpectrum[FontSpectrumCount]);}).attr("class","Options").attr("id","FontChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2425).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.selectAll(".sequence").transition().attr("font-size",function() {return parseFloat(Or_Seq_Font_Size)*parseFloat(FontSpectrum[FontSpectrumCount]);}).delay(0).duration(500);
});
d3.select("#annotation").append("path").attr("d","M 3400,2350 L 3425,2400 L 3400,2450 Z").attr("class","Options").attr("id","Rtriangle2").attr("fill","DimGray").attr("fill-opacity", 0.8)
.on("mouseover",function() {
d3.select("#Rtriangle2").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#Rtriangle2").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
if (FontSpectrumCount == 8) {
FontSpectrumCount = 0;
} else {
FontSpectrumCount = FontSpectrumCount + 1;
}
d3.select("#FontChoice").remove();
d3.select("#annotation").append("text").text(function() {return "Font-Size: "+String(FontSpectrum[FontSpectrumCount]);}).attr("class","Options").attr("id","FontChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2425).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.selectAll(".sequence").transition().attr("font-size",function() {return parseFloat(Or_Seq_Font_Size)*parseFloat(FontSpectrum[FontSpectrumCount]);}).delay(0).duration(500);
});
//***FontControl***
//***ConservationControl***
var ConservationSpectrum = ["10","20","30","40","50","60","70","80","90","100"];
var ConservationSpectrumCount = 9;
var ConservationValues = [];
for (var i = 0;i<ids["con"].length;i++) {
var value = d3.select(ids["con"][i]).attr("id");
value = value.replace(/^.*_Conservation-Score_/,"");
value = parseFloat(value);
ConservationValues.push(value);
}
var Max_Con_Value = d3.max(ConservationValues);
d3.select("#annotation").append("text").text(function() {if (ConservationSpectrum[ConservationSpectrumCount] == "100") {return "All";} else {return "%"+String(100-ConservationSpectrum[ConservationSpectrumCount])+" max";}}).attr("class","Options").attr("id","ConsChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2137).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.select("#annotation").append("path").attr("d","M 2800,2075 L 2775,2125 L 2800,2175 Z").attr("class","Options").attr("id","Ltriangle3").attr("fill","DimGray").attr("fill-opacity", 0.8)
.on("mouseover",function() {
d3.select("#Ltriangle3").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#Ltriangle3").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
if (ConservationSpectrumCount == 9) {
ConservationSpectrumCount = 0;
} else {
ConservationSpectrumCount = ConservationSpectrumCount + 1;
}
d3.select("#ConsChoice").remove();
d3.select("#annotation").append("text").text(function() {if (ConservationSpectrum[ConservationSpectrumCount] == "100") {return "All";} else {return "%"+String(100-ConservationSpectrum[ConservationSpectrumCount])+" max";}}).attr("class","Options").attr("id","ConsChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2137).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible").transition().attr("fill-opacity",0.9).delay(0).duration(750);
var Cons_code = "";
for (var i=0;i<ids["con"].length;i++) {
var Cons_code_piece = 'd3.select(ids["con"]['+i+']).transition().attr("fill-opacity",function() {var value = ConservationValues['+i+']; var threshold = (100 - parseFloat(ConservationSpectrum[ConservationSpectrumCount]))/100*Max_Con_Value; if(value < threshold){return 0.0;}else{return 1.0;}}).attr("stroke-opacity",function() {var value = ConservationValues['+i+']; var threshold = (100 - parseFloat(ConservationSpectrum[ConservationSpectrumCount]))/100*Max_Con_Value; if(value < threshold){return 0.0;}else{return 1.0;}}).delay(0).duration(500);';
Cons_code = Cons_code+Cons_code_piece+" ";
}
eval(Cons_code);
});
d3.select("#annotation").append("path").attr("d","M 3200,2075 L 3225,2125 L 3200,2175 Z").attr("class","Options").attr("id","Rtriangle3").attr("fill","DimGray").attr("fill-opacity", 0.8)
.on("mouseover",function() {
d3.select("#Rtriangle3").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#Rtriangle3").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function() {
if (ConservationSpectrumCount == 0) {
ConservationSpectrumCount = 9;
} else {
ConservationSpectrumCount = ConservationSpectrumCount - 1;
}
d3.select("#ConsChoice").remove();
d3.select("#annotation").append("text").text(function() {if (ConservationSpectrum[ConservationSpectrumCount] == "100") {return "All";} else {return "%"+String(100-ConservationSpectrum[ConservationSpectrumCount])+" max";}}).attr("class","Options").attr("id","ConsChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2137).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible").transition().attr("fill-opacity",0.9).delay(0).duration(750);
var Cons_code = "";
for (var i=0;i<ids["con"].length;i++) {
var Cons_code_piece = 'd3.select(ids["con"]['+i+']).transition().attr("fill-opacity",function() {var value = ConservationValues['+i+']; var threshold = (100 - parseFloat(ConservationSpectrum[ConservationSpectrumCount]))/100*Max_Con_Value; if(value < threshold){return 0.0;}else{return 1.0;}}).attr("stroke-opacity",function() {var value = ConservationValues['+i+']; var threshold = (100 - parseFloat(ConservationSpectrum[ConservationSpectrumCount]))/100*Max_Con_Value; if(value < threshold){return 0.0;}else{return 1.0;}}).delay(0).duration(500);';
Cons_code = Cons_code+Cons_code_piece+" ";
}
eval(Cons_code);
});
//***ConservationControl***
//***Database Control***
var DropDownClickSnv = 0;
var DropDownClickTile = 0;
d3.select("#annotation").append("text").text("Snv").attr("class","Options_Lights").attr("id","LHtext2").attr("text-anchor","middle").attr("x", 2175).attr("y", 2600).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.5).attr("stroke-opacity",0.5).attr("visibility","visible")
.on("mouseover",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#LHtext2").transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);
d3.select("#LIbulb").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("mouseout",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#LHtext2").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(750);
d3.select("#LIbulb").transition().attr("stroke-opacity",0.5).attr("stroke-width","12px").delay(0).duration(750);
}
});
d3.select("#annotation").append("path").attr("d","M 2110,2615 Q 2140,2640, 2170,2615 L 2140,2640 Z").attr("class","Options_Lights").attr("id","LIbulb").attr("fill","Orange").attr("fill-opacity", 0.0).attr("stroke","Orange").attr("stroke-opacity",0.5).attr("stroke-width","10px")
.on("mouseover",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#LHtext2").transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);
d3.select("#LIbulb").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("mouseout",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#LHtext2").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(750);
d3.select("#LIbulb").transition().attr("stroke-opacity",0.5).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("click",function() {
if (DropDownClickSnv == 0) {
d3.select("#annotation").call(DropDownSnv);
} else {
d3.selectAll(".DropDownRectSnv").remove();
d3.selectAll(".DropDownTextSnv").remove();
}
if (DropDownClickSnv == 0) {
DropDownClickSnv = 1;
} else {
DropDownClickSnv = 0;
}
});
d3.select("#annotation").append("text").text("tilE").attr("class","Options_Lights").attr("id","RHtext2").attr("text-anchor","middle").attr("x", 3825).attr("y", 2600).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.5).attr("stroke-opacity",0.5).attr("visibility","visible")
.on("mouseover",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#RHtext2").transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);
d3.select("#RIbulb").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("mouseout",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#RHtext2").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(750);
d3.select("#RIbulb").transition().attr("stroke-opacity",0.5).attr("stroke-width","12px").delay(0).duration(750);
}
});
d3.select("#annotation").append("path").attr("d","M 3880,2615 Q 3850,2640, 3820,2615 L 3850,2640 Z").attr("class","Options_Lights").attr("id","RIbulb").attr("fill","Orange").attr("fill-opacity", 0.0).attr("stroke","Orange").attr("stroke-opacity",0.5).attr("stroke-width","10px")
.on("mouseover",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#RHtext2").transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);
d3.select("#RIbulb").transition().attr("stroke-opacity",1.0).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("mouseout",function() {
var HideMode = d3.select("#ShowOptions").attr("visibility");
if (HideMode == "hidden") {
d3.select("#RHtext2").transition().attr("fill-opacity",0.5).attr("stroke-opacity",0.5).delay(0).duration(750);
d3.select("#RIbulb").transition().attr("stroke-opacity",0.5).attr("stroke-width","12px").delay(0).duration(750);
}
})
.on("click",function() {
if (DropDownClickTile == 0) {
d3.select("#annotation").call(DropDownTile);
} else {
d3.selectAll(".DropDownRectTile").remove();
d3.selectAll(".DropDownTextTile").remove();
}
if (DropDownClickTile == 0) {
DropDownClickTile = 1;
} else {
DropDownClickTile = 0;
}
});
//***Database Control***
//***Conceal All Sequence***
d3.selectAll(".sequence").transition().attr("fill-opacity",0.0).attr("visibility","hidden").delay(0).duration(0);
//***Conceal All Sequence***
for (var i=0;i<ids["seq"].length;i++) {
var code_piece = 'd3.select(ids["seq"]['+i+']).on("mouseover", function () {d3.select("#annotation").append("text").text(function () {return d3.select(ids["seq"]['+i+']).attr("id").replace("seq_","").replace(/_/g," ");}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","200px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);d3.select(ids["seq"]['+i+']).transition().attr("font-size", function() {return parseFloat(Or_Seq_Font_Size)*9;}).style("text-shadow",Neonizer(ids["seq"]['+i+'])).delay(100).duration(300);lotusFadein(ids["seq"]['+i+']);}).on("mouseout", function () {d3.select(".text2").remove();d3.select(ids["seq"]['+i+']).transition().attr("font-size",function() {return parseFloat(Or_Seq_Font_Size)*parseFloat(FontSpectrum[FontSpectrumCount]);}).style("text-shadow","none").delay(50).duration(300);lotusFadeout();});';
code = code+code_piece+" ";
}
for (var i=0;i<ids["scat"].length;i++) {
var code_piece = 'd3.select(ids["scat"]['+i+']).on("mouseover", function () {d3.select("#annotation").append("text").text(function () {return d3.select(ids["scat"]['+i+']).attr("id").replace("scat_","").replace(/_/g," ");}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","200px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select("#annotation").append("text").text(function () {var ResidueNumber = ids["scat"]['+i+'].replace(/^.*scat_.*_/,"");return "identity: "+aminoacids[fasta_sorted[ResidueNumber-1]][0];}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-125;} else {return coordinates[1]+375;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.selectAll(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);d3.select(ids["scat"]['+i+']).transition().attr("stroke-width",Or_Scat_Size/4).attr("stroke","Orange").delay(0).duration(500);}).on("mouseout", function () {d3.selectAll(".text2").remove();d3.select(ids["scat"]['+i+']).transition().attr("stroke-width",Or_Scat_Stroke_Width).attr("stroke",Or_Scat_Stroke_Color).delay(50).duration(300);});';
code = code+code_piece+" ";
}
for (var i=0;i<ids["con"].length;i++) {
var code_piece = 'd3.select(ids["con"]['+i+']).on("mouseover", function () {d3.select("#annotation").append("text").text(function () {return d3.select(ids["con"]['+i+']).attr("id").replace("_Con",", Con").replace(/_/g," ");}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-425;} else {return coordinates[0]+425;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select("#annotation").append("text").text(function () {var ClassOfSubject = d3.select(ids["con"]['+i+']).attr("class").split(" ")[0]; if (ClassOfSubject == null || ClassOfSubject==="allCons"){return "";}else{return "domain: "+String(ClassOfSubject.replace(/_/g," "));}}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-425;} else {return coordinates[0]+425;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-125;} else {return coordinates[1]+375;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");showNewHistogramValue(ids["con"]['+i+']);d3.selectAll(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);d3.select(ids["con"]['+i+']).transition().style("stroke-width","20px").delay(0).duration(500);var ClassOfSubject = d3.select(ids["con"]['+i+']).attr("class").split(" ")[0];ClassOfSubject = "."+String(ClassOfSubject); if ((ClassOfSubject !== ".") && (ClassOfSubject !== ".allCons") && (ClassOfSubject != null)){d3.selectAll(ClassOfSubject).filter(function(){if("#"+String(d3.select(this).attr("id")) == ids["con"]['+i+']){return false;}else{return true;}}).attr("filter","url(#NeonGlow)");}}).on("mouseout", function () {var ClassOfSubject = d3.select(ids["con"]['+i+']).attr("class").split(" ")[0];ClassOfSubject = "."+String(ClassOfSubject); if ((ClassOfSubject !== ".") && (ClassOfSubject !== ".allCons") && (ClassOfSubject != null)){d3.selectAll(ClassOfSubject).attr("filter",null);}d3.selectAll(".text2").remove();d3.select(ids["con"]['+i+']).transition().style("stroke-width",Or_Con_Stroke_Width).delay(50).duration(300);}).on("click", function() { if ((ExtractionPane == "open") && (SetWhichPos != "none")){var Pos = parseInt(d3.select(ids["con"]['+i+']).attr("id").replace(/Residue_/i,"")); eval(SetWhichPos+" = "+String(Pos)); var selection = "#"+SetWhichPos; d3.select(selection).remove(); d3.select("#annotation").append("text").text(function () {return String(eval(SetWhichPos));}).attr("class","DropDownRectExtract").attr("id",SetWhichPos).attr("text-anchor","middle").attr("x", function() {if (SetWhichPos == "ExtractPosX"){return 2450;}else{return 2750;}}).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible").on("mouseover",function(){d3.select(selection).transition().attr("fill","Orange").attr("font-size",80).delay(0).duration(250);}).on("mouseout",function(){d3.select(selection).transition().attr("fill","LightGray").attr("font-size",60).delay(0).duration(250);}).on("click",function() {SetWhichPos = d3.select(this).attr("id");d3.select("#ExtractPosMessage").remove();d3.select("#annotation").append("text").text(function () {if (SetWhichPos == "ExtractPosX"){return "Select from the conservation track a start residue";}else{return "Select from the conservation track an end residue";}}).attr("class","DropDownRectExtract").attr("id","ExtractPosMessage").attr("text-anchor","middle").attr("x", 3000).attr("y", 3400).attr("font-family","Arial").attr("font-size","100px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select("#ExtractPosMessage").transition().attr("fill-opacity",0.5).delay(0).duration(750);}); d3.select("#ExtractPosMessage").remove(); SetWhichPos ="none";}});';
code = code+code_piece+" ";
}
for (var i=0;i<ids["mut"].length;i++) {
var code_piece = 'd3.select(ids["mut"]['+i+']).on("mouseover", function () {d3.select("#annotation").append("text").text(function () {return d3.select(ids["mut"]['+i+']).attr("id").replace(/_rsID.*/g,"").replace(/[A-Z]/,function() {var id = d3.select(ids["mut"]['+i+']).attr("id"); var first =id.substring(0,1); return aminoacids[first][0]+" ";}).replace(/[A-Z]$/,function () {var id = d3.select(ids["mut"]['+i+']).attr("id"); var id = id.replace(/_rsID.*/,"");var last = id.slice(-1);if (last != "X"){return " to "+aminoacids[last][0];}else{return " to Stop codon";}}) ;}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-500;} else {return coordinates[0]+500;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-200;} else {return coordinates[1]+200;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");returnPredictionScores(predictionDatabase,ids["mut"]['+i+']);d3.selectAll(".text2").transition().attr("fill-opacity",0.9).style("opacity",0.9).delay(500).duration(500);d3.select(ids["mut"]['+i+']).transition().attr("font-size", function () {return parseFloat(Or_Mut_Font_Size)*3;}).style("text-shadow",Neonizer(ids["mut"]['+i+'])).delay(100).duration(300);}).on("mouseout", function () {d3.selectAll(".text2").remove();d3.select(ids["mut"]['+i+']).transition().attr("font-size",Or_Mut_Font_Size).style("text-shadow","none").delay(50).duration(300);}).on("click",function() {var rsID = d3.select(ids["mut"]['+i+']).attr("id"); rsID = rsID.replace(/.*_rsID_rs/,"").replace(/_[1-9]+[0-9]*_[0-9]+$/,""); var link = String("http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=")+ String(rsID); window.open(link);});';
code = code+code_piece+" ";
}
for (var i=0;i<ids["connector"].length;i++) {
var code_piece = 'd3.select(ids["connector"]['+i+']).on("mouseover", function () {d3.select("#annotation").append("text").text(function () {var IdOfConnectorText = d3.select(ids["connector"]['+i+']).attr("id"); IdOfConnectorText=IdOfConnectorText.replace("Connector_","").split("-"); if(IdOfConnectorText[0] == IdOfConnectorText[1]){return "Residue "+String(IdOfConnectorText[0]);}else{return "Residues "+String(IdOfConnectorText[0])+" to "+String(IdOfConnectorText[1]);}}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","200px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);d3.select(ids["connector"]['+i+']).transition().attr("font-size", function() {return parseFloat(Or_Connector_Font_Size)*3;}).style("text-shadow",Neonizer(ids["connector"]['+i+'])).delay(100).duration(300);}).on("mouseout", function () {d3.select(".text2").remove();d3.select(ids["connector"]['+i+']).transition().attr("font-size",function() {return parseFloat(Or_Connector_Font_Size);}).style("text-shadow","none").delay(50).duration(300);});';
code = code+code_piece+" ";
}
for (var i=0;i<ids["tile"].length;i++) {
var id = d3.select(ids["tile"][i]).attr("id");
if (id.match(/sub/)) {
var code_piece = 'd3.select(ids["tile"]['+i+']).on("mouseover",function() {d3.select(ids["tile"]['+i+']).transition().style("stroke","Orange").style("stroke-width","10px").delay(0).duration(500); var cDNA_pos = parseFloat(d3.select(ids["tile"]['+i+']).attr("id").replace(/tile[0-9]*_/,"")); var protein_pos; if (cDNA_pos % 3 != 0) {protein_pos = parseInt(cDNA_pos/3);} else {protein_pos = parseInt(cDNA_pos/3)-1;} d3.select("#annotation").append("path").attr("d",function () {return "M "+String((parseFloat(Or_Tile_Coordinates['+i+']["TopLeftCornerx"])+parseFloat(Or_Tile_Coordinates['+i+']["TopRightCornerx"]))/2)+","+String((parseFloat(Or_Tile_Coordinates['+i+']["TopLeftCornery"])+parseFloat(Or_Tile_Coordinates['+i+']["TopRightCornery"]))/2)+" L "+String((parseFloat(Or_Tile_Coordinates['+i+']["TopLeftCornerx"])+parseFloat(Or_Tile_Coordinates['+i+']["TopRightCornerx"]))/2)+","+String((parseFloat(Or_Tile_Coordinates['+i+']["TopLeftCornery"])+parseFloat(Or_Tile_Coordinates['+i+']["TopRightCornery"]))/2);}).attr("id","TileLineToDestination").attr("class","TileLines").attr("stroke","Orange").attr("stroke-width","8px").attr("stroke-opacity",0.75); d3.select("#TileLineToDestination").transition().attr("d",function () {return "M "+String((parseFloat(Or_Tile_Coordinates['+i+']["TopLeftCornerx"])+parseFloat(Or_Tile_Coordinates['+i+']["TopRightCornerx"]))/2)+","+String((parseFloat(Or_Tile_Coordinates['+i+']["TopLeftCornery"])+parseFloat(Or_Tile_Coordinates['+i+']["TopRightCornery"]))/2)+" L "+String(3000+2250*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180))+","+String(3000-2250*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180));}).delay(0).duration(500); d3.select("#annotation").append("text").text(function () {return "Substitution at position "+String(protein_pos+1);}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);}).on("mouseout",function() {d3.select(ids["tile"]['+i+']).transition().style("stroke",Or_Tile_Stroke_Color['+i+']).style("stroke-width",Or_Tile_Stroke_Width['+i+']).delay(0).duration(500); d3.selectAll(".TileLines").remove(); d3.selectAll(".text2").remove();}).on("click",function() {var rsID = d3.select(ids["tile"]['+i+']).attr("tilersid"); rsID = rsID.replace(/^rs/,""); var link = String("http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=")+ String(rsID); window.open(link);});';
code = code+code_piece+" ";
} else if (id.match(/in/)) {
var code_piece = 'd3.select(ids["tile"]['+i+']).on("mouseover",function() {d3.select(ids["tile"]['+i+']).transition().style("stroke","Orange").style("stroke-width","10px").delay(0).duration(500); var cDNA_pos = parseFloat(d3.select(ids["tile"]['+i+']).attr("id").replace(/tile[0-9]*_/,"")); var protein_pos; if (cDNA_pos % 3 != 0) {protein_pos = parseInt(cDNA_pos/3);} else {protein_pos = parseInt(cDNA_pos/3)-1;} var ChangeLength = parseInt(d3.select(ids["tile"]['+i+']).attr("id").replace(/tile[0-9]*_[0-9]*_/,"")); d3.select("#annotation").append("path").attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopLeftCornerx"]+","+Or_Tile_Coordinates['+i+']["TopLeftCornery"]+" L "+Or_Tile_Coordinates['+i+']["TopLeftCornerx"]+","+Or_Tile_Coordinates['+i+']["TopLeftCornery"];}).attr("id","TileLineToDestination1").attr("class","TileLines").attr("stroke","Orange").attr("stroke-width","8px").attr("stroke-opacity",0.75); d3.select("#annotation").append("path").attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopRightCornerx"]+","+Or_Tile_Coordinates['+i+']["TopRightCornery"]+" L "+Or_Tile_Coordinates['+i+']["TopRightCornerx"]+","+Or_Tile_Coordinates['+i+']["TopRightCornery"];}).attr("id","TileLineToDestination2").attr("class","TileLines").attr("stroke","Orange").attr("stroke-width","8px").attr("stroke-opacity",0.75);d3.select("#TileLineToDestination1").transition().attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopLeftCornerx"]+","+Or_Tile_Coordinates['+i+']["TopLeftCornery"]+" L "+String(3000+2250*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180))+","+String(3000-2250*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180));}).delay(0).duration(500); d3.select("#TileLineToDestination2").transition().attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopRightCornerx"]+","+Or_Tile_Coordinates['+i+']["TopRightCornery"]+" L "+String(3000+2250*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180))+","+String(3000-2250*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180));}).delay(0).duration(500); d3.select("#annotation").append("text").text(function () {return "Insertion of "+ChangeLength+" aa "+"at position "+String(protein_pos+1)+String(Or_Tile_FrameCharacter['+i+']);}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);}).on("mouseout",function() {d3.select(ids["tile"]['+i+']).transition().style("stroke",Or_Tile_Stroke_Color['+i+']).style("stroke-width",Or_Tile_Stroke_Width['+i+']).delay(0).duration(500); d3.selectAll(".TileLines").remove(); d3.selectAll(".text2").remove();}).on("click",function() {var rsID = d3.select(ids["tile"]['+i+']).attr("tilersid"); rsID = rsID.replace(/^rs/,""); var link = String("http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=")+ String(rsID); window.open(link);});';
code = code+code_piece+" ";
} else if (id.match(/del/)) {
var code_piece = 'd3.select(ids["tile"]['+i+']).on("mouseover",function() {d3.select(ids["tile"]['+i+']).transition().style("stroke","Orange").style("stroke-width","10px").delay(0).duration(500); var cDNA_pos = parseFloat(d3.select(ids["tile"]['+i+']).attr("id").replace(/tile[0-9]*_/,"")); var protein_pos; if (cDNA_pos % 3 != 0) {protein_pos = parseInt(cDNA_pos/3);} else {protein_pos = parseInt(cDNA_pos/3)-1;} var ChangeLength = parseInt(d3.select(ids["tile"]['+i+']).attr("id").replace(/tile[0-9]*_[0-9]*_/,"")); d3.select("#annotation").append("path").attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopLeftCornerx"]+","+Or_Tile_Coordinates['+i+']["TopLeftCornery"]+" L "+Or_Tile_Coordinates['+i+']["TopLeftCornerx"]+","+Or_Tile_Coordinates['+i+']["TopLeftCornery"];}).attr("id","TileLineToDestination1").attr("class","TileLines").attr("stroke","Orange").attr("stroke-width","8px").attr("stroke-opacity",0.75); d3.select("#annotation").append("path").attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopRightCornerx"]+","+Or_Tile_Coordinates['+i+']["TopRightCornery"]+" L "+Or_Tile_Coordinates['+i+']["TopRightCornerx"]+","+Or_Tile_Coordinates['+i+']["TopRightCornery"];}).attr("id","TileLineToDestination2").attr("class","TileLines").attr("stroke","Orange").attr("stroke-width","8px").attr("stroke-opacity",0.75);d3.select("#TileLineToDestination1").transition().attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopLeftCornerx"]+","+Or_Tile_Coordinates['+i+']["TopLeftCornery"]+" L "+String(3000+2250*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180))+","+String(3000-2250*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*protein_pos))-CorrectionFactor*protein_pos)/180));}).delay(0).duration(500); d3.select("#TileLineToDestination2").transition().attr("d",function () {return "M "+Or_Tile_Coordinates['+i+']["TopRightCornerx"]+","+Or_Tile_Coordinates['+i+']["TopRightCornery"]+" L "+String(3000+2250*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(protein_pos+ChangeLength)))-CorrectionFactor*protein_pos)/180))+","+String(3000-2250*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(protein_pos+ChangeLength)))-CorrectionFactor*protein_pos)/180));}).delay(0).duration(500); d3.select("#annotation").append("text").text(function () {return "Deletion of "+ChangeLength+" aa "+"at position "+String(protein_pos+1)+String(Or_Tile_FrameCharacter['+i+']);}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-250;} else {return coordinates[0]+250;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-250;} else {return coordinates[1]+250;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");d3.select(".text2").transition().attr("fill-opacity",0.9).delay(500).duration(500);}).on("mouseout",function() {d3.select(ids["tile"]['+i+']).transition().style("stroke",Or_Tile_Stroke_Color['+i+']).style("stroke-width",Or_Tile_Stroke_Width['+i+']).delay(0).duration(500); d3.selectAll(".TileLines").remove(); d3.selectAll(".text2").remove();}).on("click",function() {var rsID = d3.select(ids["tile"]['+i+']).attr("tilersid"); rsID = rsID.replace(/^rs/,""); var link = String("http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=")+ String(rsID); window.open(link);});';
code = code+code_piece+" ";
}
}
eval(code);
code = "completed";
//***Email and Logo***
var logo = "data:image/png;base64,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";
d3.select("#master").append("svg:image").attr("xlink:href",logo).attr("title","contact").attr("alt","contact").attr("x",25).attr("y",700).attr("width","500px").attr("height","282px").attr("id","logo").attr("style","opacity:0.4")
.on("mouseover",function() {
if(flash == 0) {
d3.select(this).transition().attr("style","outline:6px solid rgba(255,165,0,0.5); opacity:1.0;").delay(0).duration(250);
}
})
.on("mouseout",function() {
if(flash == 0) {
d3.select(this).transition().attr("style","outline:none; opacity:0.4;").delay(0).duration(250);
}
})
.on("click",function() {
if(flash == 0) {
window.open("mailto:ibrahim.tanyalcin@i-pv.org?subject= &body=");
}
});
//***Email and Logo***
//***Missense Link Control***
d3.select("#annotation").append("text").text("Hide missense links").attr("class","LinkControl").attr("id","MissenseLinkControl").attr("text-anchor","middle").attr("x", 290).attr("y", 400).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover",function() {
d3.select("#MissenseLinkControl").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#MissenseLinkControl").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click", function () {
d3.select("#MissenseLinkControl").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#MissenseLinkControl2").transition().attr("visibility","visible").delay(0).duration(0);
d3.select(document.body).select("#master").select("#plot3").selectAll("*").filter(function () {if (d3.select(this).attr("id")){return 0;}else{return 1;}}).each(function () {d3.select(this).transition().attr("fill-opacity",0.0).attr("stroke-opacity",0.0).delay(0).duration(750);});
});
d3.select("#annotation").append("text").text("Show missense links").attr("class","LinkControl").attr("id","MissenseLinkControl2").attr("text-anchor","middle").attr("x", 290).attr("y", 400).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","hidden")
.on("mouseover",function() {
d3.select("#MissenseLinkControl2").transition().attr("fill","Orange").delay(0).duration(0);
})
.on("mouseout",function() {
d3.select("#MissenseLinkControl2").transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click", function () {
d3.select("#MissenseLinkControl").transition().attr("visibility","visible").delay(0).duration(0);
d3.select("#MissenseLinkControl2").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select(document.body).select("#master").select("#plot3").selectAll("*").filter(function () {if (d3.select(this).attr("id")){return 0;}else{return 1;}}).each(function () {d3.select(this).transition().attr("fill-opacity",1.0).attr("stroke-opacity",1.0).delay(0).duration(750);});
});
//***Missense Link Control***
//***AminoAcidLength and Extract***
var ExtractionPane = "closed";
var ExtractPosX = 1;
var ExtractPosY = parseInt(fasta_sorted.length);
var ItemsPerLine = 50;
var SetWhichPos = "none";
var DropDownClickExtract = 0;
var ExtractRectCount = ["1","2","3"];
d3.select("#annotation").append("text").text(function() {return "length: "+String(fasta_sorted.length)+" aa";}).attr("class","Options").attr("id","OverviewLength").attr("text-anchor","middle").attr("x", 3000).attr("y", 2800).attr("font-family","Arial").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover",function() {
d3.select("#OverviewLength").transition().attr("font-size","120px").attr("fill","Orange").delay(0).duration(500);
d3.selectAll(".overviews").style("opacity",0);
})
.on("mouseout",function() {
d3.select("#OverviewLength").transition().attr("font-size","60px").attr("fill","DimGray").delay(0).duration(500);
d3.selectAll(".overviews").style("opacity",1);
})
.on("click",function() {
if (DropDownClickExtract == 0) {
//Close other open overview tabs
if (MarkPane === "open") {
d3.selectAll(".htmlElements").remove();
d3.selectAll(".DropDownRectMark").remove();
DropDownClickMark = 0;
MarkPane = "closed";
}
//Close other open overview tabs
d3.select("#annotation").call(DropDownExtract);
} else {
d3.selectAll(".DropDownRectExtract").remove();
ExtractionPane = "closed";
}
if (DropDownClickExtract == 0) {
DropDownClickExtract = 1;
} else {
DropDownClickExtract = 0;
}
});
//***AminoAcidLength and Extract***
//***Print***
var flash = 0;
d3.select("#annotation").append("text").text("Snapshot").attr("class","Print").attr("id","Snapshot").attr("text-anchor","middle").attr("x", 175).attr("y", 600).attr("font-family","Arial").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover",function() {
d3.selectAll(".Cell").remove();
d3.select("#annotation").append("path").attr("d", "M 550,450 L 550,450 L 550,450 L 550,450 L 550,450 L 550,450 L 550,450 L 550,450 L 550,450 L 550,450 L 550,450 Z").attr("class","Cell").attr("id","CellPhone").attr("fill-opacity",0.0).attr("stroke-width",10).attr("stroke","Orange");
d3.select("#CellPhone").transition().attr("d","M 550,450 L 500,450 Q 450,450, 450,500 L 450,700 Q 450,750, 500,750 L 550,750 L 600,750 Q 650,750, 650,700 L 650,500 Q 650,450 600,450 L 550,450 Z").delay(0).duration(500);
d3.select("#annotation").append("circle").attr("class","Cell").attr("id","CellPhoneCam").attr("cx",600).attr("cy",500).attr("r",10).attr("fill","DodgerBlue").attr("fill-opacity",0).attr("stroke","Orange").attr("stroke-opacity",0).attr("stroke-width",6);
d3.select("#CellPhoneCam").transition().attr("stroke-opacity",0.9).delay(500).duration(250);
d3.select("#Snapshot").transition().attr("font-size","80px").attr("fill","Orange").delay(0).duration(500);
})
.on("mouseout",function() {
d3.select("#Snapshot").transition().attr("font-size","60px").attr("fill","DimGray").delay(0).duration(500);
if (flash == 0) {
d3.selectAll(".Cell").remove();
} else {
d3.select("#logo").transition().attr("style","opacity:0.75;").delay(2000).duration(0);
var SetTimeOut = function () {
d3.selectAll(".Cell").remove();
flash = 0;
return true;
};
d3.timer(SetTimeOut,2000);
}
})
.on("click", function () {
d3.select("#logo").transition().attr("style","opacity:0;").delay(0).duration(0);
d3.select("#print_script").remove();
d3.select("#annotation").append("circle").attr("class","Cell").attr("id","CellPhoneFlash").attr("cx",350).attr("cy",450).attr("r",450).attr("fill","White").attr("fill-opacity",1).attr("stroke","Orange").attr("stroke-opacity",0).attr("stroke-width",6);
flash = 1;
var SetTimeOut = function() {
d3.select(document.head).append("head:script").attr("id","print_script").attr("type","text/javascript").attr("src","https://nytimes.github.io/svg-crowbar/svg-crowbar.js").attr("integrity","sha384-1inWUU7B2uXOPXdF+Jb2MzKQhEbzk277psmlvjiioy5z/iIJ6gqxfnvJKRhS8SKM").attr("crossorigin","anonymous");
return true;
};
d3.timer(SetTimeOut,250);
});
//***Print***
//***Subs***
//***This is for Aminoacid Property selection
function DropDown(selection) {
selection
.selectAll("rectanglesDropDown")
.data(AminoAcidProperties)
.enter()
.append("rect")
.attr("x",2700)
.attr("y",function (d,i) {return 2350+i*101;})
.attr("height",100)
.attr("width",600)
.attr("fill","DimGray")
.attr("fill-opacity",0.0)
.attr("stroke","DimGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownRect"+String(i);})
.attr("class","DropDownRect")
.on("mouseover",function(d,i) {
d3.select("#DropDownRect"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRect"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function (d,i){
var selected = i;
AminoAcidPropertiesCount = i;
d3.select("#PropChoice").remove();
d3.select("#annotation").append("text").text(function(){return AminoAcidProperties[AminoAcidPropertiesCount];}).attr("class","Options").attr("id","PropChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2275).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("click",function() {
if (DropDownClick == 0) {
d3.select("#annotation").call(DropDown);
} else {
d3.selectAll(".DropDownRect").remove();
d3.selectAll(".DropDownText").remove();
}
if (DropDownClick == 0) {
DropDownClick = 1;
} else {
DropDownClick = 0;
}
});
d3.select("#PropChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.selectAll(".scatter").data(ids["scat"]).each(function(d,i) {var ResidueNumber = d.replace(/^.*scat_.*_/,"");d3.select(d).transition().attr("fill-opacity",function (){var aminoacid = fasta_sorted[ResidueNumber-1];if(AminoAcidProperties[selected] == "All" || d.match(AminoAcidProperties[selected]) || aminoacids_OtherProperties[fasta_sorted[ResidueNumber-1]].some(function(x){return x.match(AminoAcidProperties[selected]);}) || (AminoAcidProperties[AminoAcidPropertiesCount] == "Sequence Display" && aminoacids[aminoacid][2] == "Clicked")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
WhatsClicked = [];
for (i=0;i<d3.keys(aminoacids).length;i++) {
if(aminoacids[d3.keys(aminoacids)[i]][2]=="Clicked") {
WhatsClicked.push(d3.keys(aminoacids)[i]);
}
}
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
});
d3.selectAll(".DropDownRect").data(AminoAcidProperties).each(function(d,i) {d3.select("#DropDownRect"+String(i)).transition("fadein").attr("fill-opacity",0.7).delay(function() {return (500/(AminoAcidProperties.length-1))*i;}).duration(500);});
selection
.selectAll("textsDropDown")
.data(AminoAcidProperties)
.enter()
.append("text")
.attr("x",3000)
.attr("y",function (d,i) {return 2425+i*100;})
.text(function(d,i) {return AminoAcidProperties[i];})
.attr("text-anchor","middle")
.attr("font-family","sans-serif")
.attr("font-size","55px")
.attr("fill","LightGray")
.attr("fill-opacity",0.0)
.attr("stroke","LightGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownText"+String(i);})
.attr("class","DropDownText")
.on("mouseover",function(d,i) {
d3.select("#DropDownRect"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRect"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function (d,i){
var selected = i;
AminoAcidPropertiesCount = i;
d3.select("#PropChoice").remove();
d3.select("#annotation").append("text").text(function(){return AminoAcidProperties[AminoAcidPropertiesCount];}).attr("class","Options").attr("id","PropChoice").attr("text-anchor","middle").attr("x", 3000).attr("y", 2275).attr("font-family","sans-serif").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("click",function() {
if (DropDownClick == 0) {
d3.select("#annotation").call(DropDown);
} else {
d3.selectAll(".DropDownRect").remove();
d3.selectAll(".DropDownText").remove();
}
if (DropDownClick == 0) {
DropDownClick = 1;
} else {
DropDownClick = 0;
}
});
d3.select("#PropChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
d3.selectAll(".scatter").data(ids["scat"]).each(function(d,i) {var ResidueNumber = d.replace(/^.*scat_.*_/,"");d3.select(d).transition().attr("fill-opacity",function (){var aminoacid = fasta_sorted[ResidueNumber-1];if(AminoAcidProperties[selected] == "All" || d.match(AminoAcidProperties[selected]) || aminoacids_OtherProperties[fasta_sorted[ResidueNumber-1]].some(function(x){return x.match(AminoAcidProperties[selected]);}) || (AminoAcidProperties[AminoAcidPropertiesCount] == "Sequence Display" && aminoacids[aminoacid][2] == "Clicked")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
WhatsClicked = [];
for (i=0;i<d3.keys(aminoacids).length;i++) {
if(aminoacids[d3.keys(aminoacids)[i]][2]=="Clicked") {
WhatsClicked.push(d3.keys(aminoacids)[i]);
}
}
//+++Dynamically Keeps Track of Clicked aminoacids AT THE TIME OF FEATURE SELECTION (either by clicking arrows or the dropdown) which changes the scatter track+++
});
d3.selectAll(".DropDownText").data(AminoAcidProperties).each(function(d,i) {d3.select("#DropDownText"+String(i)).transition("fadein").attr("fill-opacity",0.9).delay(function() {return (500/(AminoAcidProperties.length-1))*i;}).duration(500);});
}
//***This is for SNVs***
function DropDownSnv(selection) {
selection
.selectAll("rectanglesDropDownSnv")
.data(MutDB)
.enter()
.append("rect")
.attr("x",2100)
.attr("y",function (d,i) {return 2700+i*101;})
.attr("height",100)
.attr("width",600)
.attr("fill","DimGray")
.attr("fill-opacity",0.0)
.attr("stroke","DimGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownRectSnv"+String(i);})
.attr("class","DropDownRectSnv")
.on("mouseover",function(d,i) {
d3.select("#DropDownRectSnv"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRectSnv"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function (d,i){
var selected = MutDB[i];
d3.selectAll(".mut").data(ids["mut"]).each(function(d,i) {var database_source = d3.select(ids["mut"][i]).attr("dbsource");var regexp = new RegExp(selected,"i");d3.select(d).transition().attr("fill-opacity",function (){if((database_source.match(regexp) || (selected == "All") || ((selected == "Stop")&&(d3.select(ids["mut"][i]).attr("id").match(/x/i))) || (selected.match(/synonymous/gi)&&(selected===synOrNonsyn(d))) || (selected==="pXtoY" && pXtoY(d)))&&(selected != "None")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
});
d3.selectAll(".DropDownRectSnv").data(MutDB).each(function(d,i) {d3.select("#DropDownRectSnv"+String(i)).transition("fadein").attr("fill-opacity",0.7).delay(function() {return (500/(MutDB.length))*i;}).duration(500);});
selection
.selectAll("textsDropDownSnv")
.data(MutDB)
.enter()
.append("text")
.attr("x",2400)
.attr("y",function (d,i) {return 2775+i*100;})
.text(function(d,i) {return MutDB[i];})
.attr("text-anchor","middle")
.attr("font-family","sans-serif")
.attr("font-size","55px")
.attr("fill","LightGray")
.attr("fill-opacity",0.0)
.attr("stroke","LightGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownTextSnv"+String(i);})
.attr("class","DropDownTextSnv")
.on("mouseover",function(d,i) {
d3.select("#DropDownRectSnv"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRectSnv"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function (d,i){
var selected = MutDB[i];
d3.selectAll(".mut").data(ids["mut"]).each(function(d,i) {var database_source = d3.select(ids["mut"][i]).attr("dbsource");var regexp = new RegExp(selected,"i");d3.select(d).transition().attr("fill-opacity",function (){if((database_source.match(regexp) || (selected == "All") || ((selected == "Stop")&&(d3.select(ids["mut"][i]).attr("id").match(/x/i))) || (selected.match(/synonymous/gi)&&(selected===synOrNonsyn(d))) || (selected==="pXtoY" && pXtoY(d)))&&(selected != "None")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
});
d3.selectAll(".DropDownTextSnv").data(MutDB).each(function(d,i) {d3.select("#DropDownTextSnv"+String(i)).transition("fadein").attr("fill-opacity",0.9).delay(function() {return (500/(MutDB.length))*i;}).duration(500);});
}
//***This is for tiles***
function DropDownTile(selection) {
selection
.selectAll("rectanglesDropDownTile")
.data(TileDB)
.enter()
.append("rect")
.attr("x",3300)
.attr("y",function (d,i) {return 2700+i*101;})
.attr("height",100)
.attr("width",600)
.attr("fill","DimGray")
.attr("fill-opacity",0.0)
.attr("stroke","DimGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownRectTile"+String(i);})
.attr("class","DropDownRectTile")
.on("mouseover",function(d,i) {
d3.select("#DropDownRectTile"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRectTile"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function (d,i){
var selected = TileDB[i];
d3.selectAll(".tile").data(ids["tile"]).each(function(d,i) {var database_source = d3.select(ids["tile"][i]).attr("dbsource");var id = d3.select(ids["tile"][i]).attr("id");var regexp = new RegExp(selected,"i");d3.select(d).transition().attr("fill-opacity",function (){if((database_source.match(regexp) || id.match(regexp) || (selected == "All"))&&(selected != "None")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
});
d3.selectAll(".DropDownRectTile").data(TileDB).each(function(d,i) {d3.select("#DropDownRectTile"+String(i)).transition("fadein").attr("fill-opacity",0.7).delay(function() {return (500/(TileDB.length))*i;}).duration(500);});
selection
.selectAll("textsDropDownTile")
.data(TileDB)
.enter()
.append("text")
.attr("x",3600)
.attr("y",function (d,i) {return 2775+i*100;})
.text(function(d,i) {return TileDB[i];})
.attr("text-anchor","middle")
.attr("font-family","sans-serif")
.attr("font-size","55px")
.attr("fill","LightGray")
.attr("fill-opacity",0.0)
.attr("stroke","LightGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownTextTile"+String(i);})
.attr("class","DropDownTextTile")
.on("mouseover",function(d,i) {
d3.select("#DropDownRectTile"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRectTile"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})
.on("click",function (d,i){
var selected = TileDB[i];
d3.selectAll(".tile").data(ids["tile"]).each(function(d,i) {var database_source = d3.select(ids["tile"][i]).attr("dbsource");var id = d3.select(ids["tile"][i]).attr("id");var regexp = new RegExp(selected,"i");d3.select(d).transition().attr("fill-opacity",function (){if((database_source.match(regexp) || id.match(regexp) || (selected == "All"))&&(selected != "None")){return 1.0;} else {return 0.0;}}).delay(0).duration(750);});
});
d3.selectAll(".DropDownTextTile").data(TileDB).each(function(d,i) {d3.select("#DropDownTextTile"+String(i)).transition("fadein").attr("fill-opacity",0.9).delay(function() {return (500/(TileDB.length))*i;}).duration(500);});
}
//***This is for sequence extraction***
function DropDownExtract(selection) {
ExtractionPane = "open";
var FeatureHash = {"Fasta":'fasta_sorted',"Conservation":'ids["con"]',"SNVs":'ids["mut"]',"Feature":'ids["scat"]',"cDNA":'cdna',"bases":'cdna'};
var SelectedFeatureNumber = 0;
selection
.selectAll("rectanglesDropDownExtract")
.data(ExtractRectCount)
.enter()
.append("rect")
.attr("width",function(d,i) {return 1300-i*1300/Math.pow(GoldenRatio,2)})
.attr("height",100)
.attr("x",function(d,i) {return 3000-(1300-i*1300/Math.pow(GoldenRatio,2))/2;})
.attr("y",function (d,i) {return 2850+i*101;})
//here I add some attr to make the corners rounded
.attr("rx",15)
.attr("ry",15)
//here I add some attr to make the corners rounded
.attr("fill","DimGray")
.attr("fill-opacity",0.0)
.attr("stroke","DimGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownRectExtract"+String(i);})
.attr("class","DropDownRectExtract")
/*.on("mouseover",function(d,i) {
d3.select("#DropDownRectExtract"+String(i)).transition().attr("fill","Gray").delay(0).duration(0);
})
.on("mouseout",function(d,i){
d3.select("#DropDownRectExtract"+String(i)).transition().attr("fill","DimGray").delay(0).duration(0);
})*/;
d3.selectAll(".DropDownRectExtract").data(ExtractRectCount).each(function(d,i) {d3.select("#DropDownRectExtract"+String(i)).transition().attr("fill-opacity",0.9).delay(0).duration(100);});
d3.select("#annotation").append("text").text("Extract").attr("class","DropDownRectExtract").attr("id","Extract").attr("text-anchor","start").attr("x", 2600).attr("y", 3025).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover", function() {
d3.select(this).transition().attr("fill","Orange").attr("font-size",80).delay(0).duration(250);
})
.on("mouseout", function() {
d3.select(this).transition().attr("fill","LightGray").attr("font-size",60).delay(0).duration(250);
})
.on("click",function() {
if (ExtractPosX < ExtractPosY) {
var TheOutput = "";
var SelectedFeature = eval(FeatureHash[d3.keys(FeatureHash)[SelectedFeatureNumber]]);
var FileName = String(d3.keys(FeatureHash)[SelectedFeatureNumber])+".txt";
var HeaderExtract = "";
if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "Feature") {
if (String(AminoAcidProperties[AminoAcidPropertiesCount]) == "Sequence Display") {
var WhatsOnDisplay = "("+WhatsClicked.join()+")";
HeaderExtract = HeaderExtract + ">Start: "+String(ExtractPosX)+",End: "+String(ExtractPosY)+",Feature: "+String(AminoAcidProperties[AminoAcidPropertiesCount])+WhatsOnDisplay+",+ = match,- = no_match,:\n";
} else {
HeaderExtract = HeaderExtract + ">Start: "+String(ExtractPosX)+",End: "+String(ExtractPosY)+",Feature: "+String(AminoAcidProperties[AminoAcidPropertiesCount])+",+ = match,- = no_match,:\n";
}
} else {
HeaderExtract = HeaderExtract + ">Start: "+String(ExtractPosX)+",End: "+String(ExtractPosY)+","+String(d3.keys(FeatureHash)[SelectedFeatureNumber])+":\n";
}
TheOutput = TheOutput+HeaderExtract;
if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "Fasta") {
for (var i = ExtractPosX;i<=ExtractPosY;i++) {
TheOutput = TheOutput + fasta_sorted[i-1];
if ((i-ExtractPosX+1) % ItemsPerLine == 0) {
TheOutput = TheOutput + "\n";
}
}
} else if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "Conservation") {
for (var i = ExtractPosX;i<=ExtractPosY;i++) {
var MatchedElement;
for (var j = 0;j<ids["con"].length;j++) {
var ResidueNumber = d3.select(ids["con"][j]).attr("id");
ResidueNumber = parseInt(ResidueNumber.replace(/Residue_/i,""));
if (ResidueNumber == i) {
MatchedElement = j;
break;
}
}
TheOutput = TheOutput + String(parseInt(d3.select(ids["con"][MatchedElement]).attr("id").replace(/.*Conservation-Score_/i,""))) + ",";
if ((i-ExtractPosX+1) % ItemsPerLine == 0) {
TheOutput = TheOutput + "\n";
}
}
} else if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "SNVs") {
var MatchedElements = [];
for (var i = ExtractPosX;i<=ExtractPosY;i++) {
for (var j = 0;j<ids["mut"].length;j++) {
var ResidueNumber = d3.select(ids["mut"][j]).attr("id");
var Mutation = String(ResidueNumber.replace(/_.*$/ig,""));
ResidueNumber = parseInt(ResidueNumber.replace(/[A-Z]/i,""));
if (ResidueNumber == i) {
MatchedElements.push(Mutation);
}
}
}
for (var k = 1;k<=MatchedElements.length;k++) {
TheOutput = TheOutput + String(MatchedElements[k-1]) + ",";
if (k % ItemsPerLine == 0) {
TheOutput = TheOutput + "\n";
}
}
} else if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "Feature") {
for (var i = ExtractPosX;i<=ExtractPosY;i++) {
var MatchedElement;
for (var j = 0;j<ids["scat"].length;j++) {
var ResidueNumber = d3.select(ids["scat"][j]).attr("id");
ResidueNumber = parseInt(ResidueNumber.replace(/.*_/ig,""));
if (ResidueNumber == i) {
MatchedElement = j;
break;
}
}
var PlusOrMinus = parseInt(d3.select(ids["scat"][MatchedElement]).attr("fill-opacity"));
if (PlusOrMinus == 0) {
PlusOrMinus = "-";
} else {
PlusOrMinus = "+";
}
TheOutput = TheOutput + PlusOrMinus;
if ((i-ExtractPosX+1) % ItemsPerLine == 0) {
TheOutput = TheOutput + "\n";
}
}
} else if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "cDNA") {
for (var i = ExtractPosX;i<=ExtractPosY;i++) {
TheOutput = TheOutput + cdna[(i-1)*3] + cdna[(i-1)*3+1] + cdna[(i-1)*3+2];
if ((i-ExtractPosX+1)*3 % (ItemsPerLine*3) == 0) {
TheOutput = TheOutput + "\n";
}
}
} else if (String(d3.keys(FeatureHash)[SelectedFeatureNumber]) == "bases") {
for (var i = ExtractPosX,baseCounter = 1,AAcap = ExtractPosX;AAcap<=ExtractPosY;baseCounter++) {
TheOutput = TheOutput + cdna[(i-1)*3+baseCounter-1];
if (baseCounter % ItemsPerLine == 0) {
TheOutput = TheOutput + "\n";
}
if (baseCounter % 3 == 0) {
AAcap++;
}
}
}
download(TheOutput,FileName,"text/plain");
}
});
d3.select("#annotation").append("path").attr("d","M 2900,2975 L 2850,3000 L 2900,3025 Z").attr("class","DropDownRectExtract").attr("id","LExtractChoiceTriangle").attr("fill","LightGray").attr("fill-opacity", 0.9)
.on("mouseover", function() {
d3.select("#LExtractChoiceTriangle").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout",function() {
d3.select("#LExtractChoiceTriangle").transition().attr("fill","LightGray").delay(0).duration(250);
})
.on("click", function () {
d3.select("#ExtractChoice").remove();
if (SelectedFeatureNumber == 0) {
SelectedFeatureNumber = 5;
} else {
SelectedFeatureNumber = SelectedFeatureNumber - 1;
}
d3.select("#annotation").append("text").text(function () {return d3.keys(FeatureHash)[SelectedFeatureNumber];}).attr("class","DropDownRectExtract").attr("id","ExtractChoice").attr("text-anchor","middle").attr("x", 3113).attr("y", 3025).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ExtractChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
});
d3.select("#annotation").append("path").attr("d","M 3325,2975 L 3375,3000 L 3325,3025 Z").attr("class","DropDownRectExtract").attr("id","RExtractChoiceTriangle").attr("fill","LightGray").attr("fill-opacity", 0.9)
.on("mouseover", function() {
d3.select("#RExtractChoiceTriangle").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout",function() {
d3.select("#RExtractChoiceTriangle").transition().attr("fill","LightGray").delay(0).duration(250);
})
.on("click", function () {
d3.select("#ExtractChoice").remove();
if (SelectedFeatureNumber == 5) {
SelectedFeatureNumber = 0;
} else {
SelectedFeatureNumber = SelectedFeatureNumber + 1;
}
d3.select("#annotation").append("text").text(function () {return d3.keys(FeatureHash)[SelectedFeatureNumber];}).attr("class","DropDownRectExtract").attr("id","ExtractChoice").attr("text-anchor","middle").attr("x", 3113).attr("y", 3025).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ExtractChoice").transition().attr("fill-opacity",0.9).delay(0).duration(750);
});
d3.select("#annotation").append("text").text(function () {return d3.keys(FeatureHash)[SelectedFeatureNumber];}).attr("class","DropDownRectExtract").attr("id","ExtractChoice").attr("text-anchor","middle").attr("x", 3113).attr("y", 3025).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
//d3.select("#annotation").append("text").text("pos").attr("class","DropDownRectExtract").attr("text-anchor","middle").attr("x", 2400).attr("y", 2925).attr("font-family","Arial").attr("font-size","30px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text(function () {return String(ExtractPosX);}).attr("class","DropDownRectExtract").attr("id","ExtractPosX").attr("text-anchor","middle").attr("x", 2450).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover", function () {
d3.select("#ExtractPosX").transition().attr("fill","Orange").attr("font-size", 80).delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#ExtractPosX").transition().attr("fill","LightGray").attr("font-size", 60).delay(0).duration(250);
})
.on("click", function () {
SetWhichPos = 'ExtractPosX';
d3.select("#ExtractPosMessage").remove();
d3.select("#annotation").append("text").text("Select from the conservation track a start residue").attr("class","DropDownRectExtract").attr("id","ExtractPosMessage").attr("text-anchor","middle").attr("x", 3000).attr("y", 3400).attr("font-family","Arial").attr("font-size","100px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ExtractPosMessage").transition().attr("fill-opacity",0.9).delay(0).duration(750);
});
d3.select("#annotation").append("text").text("to").attr("class","DropDownRectExtract").attr("text-anchor","middle").attr("x", 2600).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text(function () {return String(ExtractPosY);}).attr("class","DropDownRectExtract").attr("id","ExtractPosY").attr("text-anchor","middle").attr("x", 2750).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover", function () {
d3.select("#ExtractPosY").transition().attr("fill","Orange").attr("font-size", 80).delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#ExtractPosY").transition().attr("fill","LightGray").attr("font-size", 60).delay(0).duration(250);
})
.on("click", function () {
SetWhichPos = 'ExtractPosY';
d3.select("#ExtractPosMessage").remove();
d3.select("#annotation").append("text").text("Select from the conservation track an end residue").attr("class","DropDownRectExtract").attr("id","ExtractPosMessage").attr("text-anchor","middle").attr("x", 3000).attr("y", 3400).attr("font-family","Arial").attr("font-size","100px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ExtractPosMessage").transition().attr("fill-opacity",0.9).delay(0).duration(750);
});
d3.select("#annotation").append("path").attr("d","M 2975,2875 L 2925,2900 L 2975,2925 Z").attr("class","DropDownRectExtract").attr("id","LItemPerLineTriangle1").attr("fill","LightGray").attr("fill-opacity", 0.9)
.on("mouseover", function () {
d3.select("#LItemPerLineTriangle1").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#LItemPerLineTriangle1").transition().attr("fill","LightGray").delay(0).duration(250);
})
.on("click",function () {
if (ItemsPerLine -1 < 1) {
ItemsPerLine = 100;
} else {
ItemsPerLine = ItemsPerLine -1;
}
d3.select("#ItemsPerLine").remove();
d3.select("#annotation").append("text").text(function () {return String(ItemsPerLine);}).attr("class","DropDownRectExtract").attr("id","ItemsPerLine").attr("text-anchor","middle").attr("x", 3050).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ItemsPerLine").transition().attr("fill-opacity",0.9).delay(0).duration(250);
});
d3.select("#annotation").append("path").attr("d","M 2925,2875 L 2875,2900 L 2925,2925 Z").attr("class","DropDownRectExtract").attr("id","LItemPerLineTriangle2").attr("fill","LightGray").attr("fill-opacity", 0.9)
.on("mouseover", function () {
d3.select("#LItemPerLineTriangle2").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#LItemPerLineTriangle2").transition().attr("fill","LightGray").delay(0).duration(250);
})
.on("click",function () {
if (ItemsPerLine - 10 < 1) {
ItemsPerLine = 100;
} else {
ItemsPerLine = ItemsPerLine -10;
}
d3.select("#ItemsPerLine").remove();
d3.select("#annotation").append("text").text(function () {return String(ItemsPerLine);}).attr("class","DropDownRectExtract").attr("id","ItemsPerLine").attr("text-anchor","middle").attr("x", 3050).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ItemsPerLine").transition().attr("fill-opacity",0.9).delay(0).duration(250);
});
d3.select("#annotation").append("text").text(function () {return String(ItemsPerLine);}).attr("class","DropDownRectExtract").attr("id","ItemsPerLine").attr("text-anchor","middle").attr("x", 3050).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("path").attr("d","M 3125,2875 L 3175,2900 L 3125,2925 Z").attr("class","DropDownRectExtract").attr("id","RItemPerLineTriangle1").attr("fill","LightGray").attr("fill-opacity", 0.9)
.on("mouseover", function () {
d3.select("#RItemPerLineTriangle1").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#RItemPerLineTriangle1").transition().attr("fill","LightGray").delay(0).duration(250);
})
.on("click",function () {
if (ItemsPerLine + 1 > 100) {
ItemsPerLine = 1;
} else {
ItemsPerLine = ItemsPerLine +1;
}
d3.select("#ItemsPerLine").remove();
d3.select("#annotation").append("text").text(function () {return String(ItemsPerLine);}).attr("class","DropDownRectExtract").attr("id","ItemsPerLine").attr("text-anchor","middle").attr("x", 3050).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ItemsPerLine").transition().attr("fill-opacity",0.9).delay(0).duration(250);
});
d3.select("#annotation").append("path").attr("d","M 3175,2875 L 3225,2900 L 3175,2925 Z").attr("class","DropDownRectExtract").attr("id","RItemPerLineTriangle2").attr("fill","LightGray").attr("fill-opacity", 0.9)
.on("mouseover", function () {
d3.select("#RItemPerLineTriangle2").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#RItemPerLineTriangle2").transition().attr("fill","LightGray").delay(0).duration(250);
})
.on("click",function () {
if (ItemsPerLine + 10 > 100) {
ItemsPerLine = 1;
} else {
ItemsPerLine = ItemsPerLine +10;
}
d3.select("#ItemsPerLine").remove();
d3.select("#annotation").append("text").text(function () {return String(ItemsPerLine);}).attr("class","DropDownRectExtract").attr("id","ItemsPerLine").attr("text-anchor","middle").attr("x", 3050).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#ItemsPerLine").transition().attr("fill-opacity",0.9).delay(0).duration(250);
});
d3.select("#annotation").append("text").text("items per line").attr("class","DropDownRectExtract").attr("text-anchor","middle").attr("x", 3450).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("Graph").attr("class","DropDownRectExtract").attr("id","Graph").attr("text-anchor","start").attr("x", 2900).attr("y", 3126).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible")
.on("mouseover", function () {
d3.select(this).transition().attr("font-size",80).attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select(this).transition().attr("font-size",60).attr("fill","LightGray").delay(0).duration(250);
})
.on("click", function () {
if (GraphOpen == "no") {
d3.select("annotation").call(InsertGraph,[GraphWdefault,GraphHdefault,2000,2375]);
} else {
d3.select("#GraphSvg").remove();
GraphOpen = "no";
GraphHnew = GraphHdefault;
GraphWnew = GraphWdefault;
GraphNewLocation = [2000,2375];
}
});
}
//***Function for Graphpad
function InsertGraph() {
GraphData = [];
var Parameters = String(arguments[1]);
Parameters = Parameters.split(",");
GraphOpen = "yes";
var GraphPadding = Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50;
var GraphW = parseInt(eval(Parameters[0]));
var GraphH = parseInt(eval(Parameters[1]));
d3.select("#annotation").append("svg").attr("id","GraphSvg").attr("x",function () {return parseInt(Parameters[2]);}).attr("y",function() {return parseInt(Parameters[3]);}).attr("width",GraphW).attr("height",GraphH).attr("draggable","true").attr("ondragstart","dragStart(event,'#GraphSvg')").attr("ondrag","dragMe(event,'#GraphSvg')").attr("ondragend","dragEnd(event,'#GraphSvg')").attr("onmouseover","hideOrshowhtmlElements('0')").attr("onmouseout","hideOrshowhtmlElements('1')");
d3.select("#GraphSvg").append("rect").attr("id","GraphBackgroundRect").attr("x",0).attr("y",0).attr("width",GraphW).attr("height",GraphH).attr("fill","DimGray").attr("fill-opacity",0.5);
d3.select("#GraphSvg").append("rect").attr("id","GraphInnerRect").attr("x",GraphPadding).attr("y",GraphPadding).attr("width",GraphW-2*GraphPadding).attr("height",GraphH-2*GraphPadding).attr("fill","LightGray").attr("fill-opacity",0.5);
d3.select("#GraphSvg").append("path").attr("id","GraphVerticalLine").attr("d",function() {return "M "+String(2*GraphPadding)+","+String(GraphPadding)+" L "+String(2*GraphPadding)+","+String(GraphH-GraphPadding);}).attr("stroke","DimGray").attr("stroke-width",6);
d3.select("#GraphSvg").append("path").attr("id","GraphHorizontalLine").attr("d",function() {return "M "+String(2*GraphPadding)+","+String(GraphH/2)+" L "+String(GraphW-GraphPadding)+","+String(GraphH/2);}).attr("stroke","DimGray").attr("stroke-width",6);
d3.select("#GraphSvg").append("path").attr("id","GraphQuattro").attr("d",function() {return "M "+String(2*GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*1)+" L "+String(GraphW-GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*1);}).attr("stroke","DimGray").attr("stroke-width",4).attr("stroke-dasharray","10,10");
d3.select("#GraphSvg").append("path").attr("id","GraphDouble").attr("d",function() {return "M "+String(2*GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*2)+" L "+String(GraphW-GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*2);}).attr("stroke","DimGray").attr("stroke-width",4).attr("stroke-dasharray","10,10");
d3.select("#GraphSvg").append("path").attr("id","GraphHalf").attr("d",function() {return "M "+String(2*GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*4)+" L "+String(GraphW-GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*4);}).attr("stroke","DimGray").attr("stroke-width",4).attr("stroke-dasharray","10,10");
d3.select("#GraphSvg").append("path").attr("id","GraphQuarter").attr("d",function() {return "M "+String(2*GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*5)+" L "+String(GraphW-GraphPadding)+","+String(GraphPadding+(GraphH/2-GraphPadding)/3*5);}).attr("stroke","DimGray").attr("stroke-width",4).attr("stroke-dasharray","10,10");
d3.select("#GraphSvg").append("text").text("x").attr("id","GraphClose").attr("x",GraphW*0.98).attr("y",GraphPadding*0.9).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*60;}).attr("fill","DodgerBlue")
.on("mouseover", function () {
d3.select("#GraphClose").transition().attr("fill", "Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#GraphClose").transition().attr("fill", "DodgerBlue").delay(0).duration(250);
})
.on("click", function () {
d3.select("#GraphSvg").remove();
GraphOpen = "no";
GraphHnew = GraphHdefault;
GraphWnew = GraphWdefault;
GraphNewLocation = [2000,2375];
//Reveal the Tabs when graph closed
hideOrshowhtmlElements ("1");
//Reveal the Tabs when graph closed
});
d3.select("#GraphSvg").append("text").text("relocate").attr("id","GraphRelocate").attr("x",GraphW*0.05).attr("y",GraphPadding*0.9).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*40;}).attr("fill","DodgerBlue")
.on("mouseover", function () {
MouseOut = 0;
d3.select("#GraphRelocate").transition().attr("fill", "Orange").delay(0).duration(250);
})
.on("mouseout", function () {
MouseOut = 1;
d3.select("#GraphRelocate").transition().attr("fill", "DodgerBlue").delay(0).duration(250);
})
.on("click", function () {
Relocate = 1;
});
d3.select("#GraphSvg").append("text").text("refresh").attr("id","GraphRefresh").attr("x",GraphW*0.15).attr("y",GraphPadding*0.9).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*40;}).attr("fill","DodgerBlue")
.on("mouseover", function () {
d3.select("#GraphRefresh").transition().attr("fill", "Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#GraphRefresh").transition().attr("fill", "DodgerBlue").delay(0).duration(250);
})
.on("click", function () {
d3.select("#GraphSvg").remove();
d3.select("annotation").call(InsertGraph,[GraphWnew,GraphHnew,GraphNewLocation[0],GraphNewLocation[1]]);
});
d3.select("#GraphSvg").append("text").text("+").attr("id","GraphEnlarge").attr("x",GraphW*0.95).attr("y",GraphPadding*0.9).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*60;}).attr("fill","DodgerBlue")
.on("mouseover", function () {
d3.select("#GraphEnlarge").transition().attr("fill", "Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#GraphEnlarge").transition().attr("fill", "DodgerBlue").delay(0).duration(250);
})
.on("click", function () {
GraphWnew = GraphWnew*1.25;
GraphHnew = GraphHnew*1.25;
d3.select("#GraphSvg").remove();
d3.select("annotation").call(InsertGraph,[GraphWnew,GraphHnew,GraphNewLocation[0],GraphNewLocation[1]]);
});
d3.select("#GraphSvg").append("text").text("-").attr("id","GraphMinimize").attr("x",GraphW*0.92).attr("y",GraphPadding*0.9).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*60;}).attr("fill","DodgerBlue")
.on("mouseover", function () {
d3.select("#GraphMinimize").transition().attr("fill", "Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select("#GraphMinimize").transition().attr("fill", "DodgerBlue").delay(0).duration(250);
})
.on("click", function () {
GraphWnew = GraphWnew*0.8;
GraphHnew = GraphHnew*0.8;
d3.select("#GraphSvg").remove();
d3.select("annotation").call(InsertGraph,[GraphWnew,GraphHnew,GraphNewLocation[0],GraphNewLocation[1]]);
});
d3.select("#GraphSvg").append("text").text(function () {return String(GraphWindowSize)+"AA";}).attr("id","GraphWindowSizeIndicator").attr("x",GraphWnew*0.5).attr("y",GraphPadding*0.8).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50;}).attr("fill","DodgerBlue");
d3.select("#GraphSvg").append("path").attr("id","GraphWindowSizeLTriangle").attr("d",function() {return "M "+String(GraphWnew*0.5-Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*100)+","+String(GraphPadding*0.2)+" L "+String(GraphWnew*0.5-Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*125)+","+String(GraphPadding*0.5)+" L"+String(GraphWnew*0.5-Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*100)+","+String(GraphPadding*0.8)+" Z";}).attr("stroke","DodgerBlue").attr("stroke-width",0).attr("fill","DodgerBlue").attr("fill-opacity",0.9)
.on("mouseover", function() {
d3.select(this).transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function() {
d3.select(this).transition().attr("fill","DodgerBlue").delay(0).duration(250);
})
.on("click", function() {
if (GraphWindowSize > 10) {
GraphWindowSize = GraphWindowSize-10;
} else {
GraphWindowSize = 100;
}
d3.select("#GraphSvg").remove();
d3.select("annotation").call(InsertGraph,[GraphWnew,GraphHnew,GraphNewLocation[0],GraphNewLocation[1]]);
});
d3.select("#GraphSvg").append("path").attr("id","GraphWindowSizeRTriangle").attr("d",function() {return "M "+String(GraphWnew*0.5+Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*100)+","+String(GraphPadding*0.2)+" L "+String(GraphWnew*0.5+Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*125)+","+String(GraphPadding*0.5)+" L"+String(GraphWnew*0.5+Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*100)+","+String(GraphPadding*0.8)+" Z";}).attr("stroke","DodgerBlue").attr("stroke-width",0).attr("fill","DodgerBlue").attr("fill-opacity",0.9)
.on("mouseover", function() {
d3.select(this).transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function() {
d3.select(this).transition().attr("fill","DodgerBlue").delay(0).duration(250);
})
.on("click", function () {
if (GraphWindowSize < 100) {
GraphWindowSize = GraphWindowSize+10;
} else {
GraphWindowSize = 10;
}
d3.select("#GraphSvg").remove();
d3.select("annotation").call(InsertGraph,[GraphWnew,GraphHnew,GraphNewLocation[0],GraphNewLocation[1]]);
});
//***When you click on Graph, what is clicked on the sequence is noted. If nothing is chosen, there is nothing to show. This is necessary due to the fact that when "Clicked" items are 0 and the feature count is 0, that graph point will be 0 instead of -3 (nothing on sequence, but feature != 0) which makes a spike.
var WhatsClickedSequence = [];
for (i=0;i<d3.keys(aminoacids).length;i++) {
if(aminoacids[d3.keys(aminoacids)[i]][2]=="Clicked") {
WhatsClickedSequence.push(d3.keys(aminoacids)[i]);
}
}
//***When you click on Graph, what is clicked on the sequence is noted. If nothing is chosen, there is nothing to show. This is necessary due to the fact that when "Clicked" items are 0 and the feature count is 0, that graph point will be 0 instead of -3 (nothing on sequence, but feature != 0) which makes a spike.
//***Crating Data Points
if (!(AminoAcidProperties[AminoAcidPropertiesCount].match(/^All$|^None$/)) && (WhatsClickedSequence.length != 0)) {
for (var i = 0; i < fasta_sorted.length/GraphWindowSize;i++) {
var AAscore = 0;
var FeatureScore = 0;
for (var j = i*GraphWindowSize;j<i*GraphWindowSize+GraphWindowSize;j++) {
if (fasta_sorted[j] !== undefined) {
if (aminoacids[fasta_sorted[j]][2] == "Clicked") {
AAscore++;
}
}
}
if(!(AminoAcidProperties[AminoAcidPropertiesCount].match(/^Sequence Display$/))) {
for (var k = i*GraphWindowSize;k<i*GraphWindowSize+GraphWindowSize;k++) {
if (fasta_sorted[k] !== undefined) {
if ((aminoacids[fasta_sorted[k]].some(function(x){return x.match(AminoAcidProperties[AminoAcidPropertiesCount]);})) || (aminoacids_OtherProperties[fasta_sorted[k]].some(function(x){return x.match(AminoAcidProperties[AminoAcidPropertiesCount]);}))) {
FeatureScore++;
}
}
}
} else {
for (var k = i*GraphWindowSize;k<i*GraphWindowSize+GraphWindowSize;k++) {
var MatchedElement;
for (var iPrime = 0;iPrime<ids["scat"].length;iPrime++) {
if(parseInt(ids["scat"][iPrime].replace(/.*_/,""))-1 == k) {
MatchedElement = iPrime;
break;
}
}
if (fasta_sorted[k] !== undefined) {
if (d3.select(ids["scat"][MatchedElement]).attr("fill-opacity") != 0) {
FeatureScore++;
}
}
}
}
var point;
if ((AAscore != 0) && (FeatureScore == 0)) {
point = 3;
} else if ((AAscore == 0) && (FeatureScore != 0)) {
point = -3;
} else if ((AAscore == 0) && (FeatureScore == 0)) {
point = 0;
} else {
point = Math.log(AAscore/FeatureScore)/Math.log(2);
point = parseFloat(point.toFixed(2));
if (point > 3) {
point = 3;
} else if (point < -3) {
point = -3;
}
}
GraphData.push(point);
}
}
if (GraphData.length != 0) {
d3.select("#GraphSvg")
.selectAll("GraphLineElements")
.data(GraphData)
.enter()
.append("path")
.attr("d",function (d,i) {
var x = 2*GraphPadding+((GraphW-3*GraphPadding)/GraphData.length)/2+i*((GraphW-3*GraphPadding)/GraphData.length);
var y = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(d-3);
return "M "+String(x)+","+String(y)+" L "+String(x)+","+String(y);
})
.attr("stroke","Orange")
.attr("stroke-width",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*12;})
.attr("class","GraphLines")
.on("mouseover", function (d,i) {
var x = 2*GraphPadding+((GraphW-3*GraphPadding)/GraphData.length)/2+i*((GraphW-3*GraphPadding)/GraphData.length);
var y = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(d-3);
d3.select(this).transition().attr("stroke-width",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*18;}).attr("stroke","DarkSalmon").delay(0).duration(250);
d3.select("#GraphSvg").append("circle").attr("id","GraphLinesStartPoint").attr("cx",function() {return x;}).attr("cy",function () {return y;}).attr("r", function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*30;}).attr("fill","DarkSalmon").attr("fill-opacity",0.75).attr("stroke","DarkSalmon").attr("stroke-opacity",0).attr("stroke-width",0);
d3.select("#GraphSvg").append("text").text(function() {return "log2 value = "+String(GraphData[i]);}).attr("id","GraphLinesLog2Value").attr("x",function() {var radius = parseFloat(d3.select("#GraphLinesStartPoint").attr("r"));if (i <= GraphData.length/2){return x+1*radius;}else {return x-15*radius;}}).attr("y",function() {var radius = parseFloat(d3.select("#GraphLinesStartPoint").attr("r"));if (GraphData[i] <= 0){return y-3*radius;}else{return y+3*radius;}}).attr("text-anchor",function() {if (i <= GraphData.length/2){return "start";}else {return "end";}}).attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*70;}).attr("fill","Black");
d3.select("#GraphSvg").append("text").text(function() {return "Aminoacids "+String(1+i*GraphWindowSize)+" to "+String(GraphWindowSize+i*GraphWindowSize);}).attr("id","GraphLinesAAindicator").attr("x",function() {return GraphWnew/2;}).attr("y",function() {if (d >= 0) {return GraphHnew*4/5;} else {return GraphHnew*1/5;}}).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*200;}).attr("fill","DarkSalmon").attr("fill-opacity",0.8);
})
.on("mouseout",function() {
d3.select(this).transition().attr("stroke-width",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*12;}).attr("stroke","Orange").delay(0).duration(250);
d3.select("#GraphLinesStartPoint").remove();
d3.select("#GraphLinesLog2Value").remove();
d3.select("#GraphLinesAAindicator").remove();
});
d3.selectAll(".GraphLines").data(GraphData).each(function(d,i) {
d3.select(this)
.transition()
.attr("d", function (){
if (i != GraphData.length-1) {
var x = 2*GraphPadding+((GraphW-3*GraphPadding)/GraphData.length)/2+i*((GraphW-3*GraphPadding)/GraphData.length);
var y = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(d-3);
var x_prime = 2*GraphPadding+((GraphW-3*GraphPadding)/GraphData.length)/2+(i+1)*((GraphW-3*GraphPadding)/GraphData.length);
var y_prime = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(GraphData[i+1]-3);
return "M "+String(x)+","+String(y)+" L "+String(x_prime)+","+String(y_prime);
}
})
.delay(function () {
var RenderLength = parseFloat((2500/(GraphData.length-1)).toFixed(0));
return i*RenderLength;
})
.duration(function () {
var RenderLength = parseFloat((2500/(GraphData.length-1)).toFixed(0));
return RenderLength;
});
});
}
//***Crating Data Points
//***blosum62squarematrix
var AminoacidsSquareMatrixNumber = {"A":["1"],"R":["2"],"N":["3"],"D":["4"],"C":["5"],"Q":["6"],"E":["7"],"G":["8"],"H":["9"],"I":["10"],"L":["11"],"K":["12"],"M":["13"],"F":["14"],"P":["15"],"S":["16"],"T":["17"],"W":["18"],"Y":["19"],"V":["20"]};
blosum62 = [
[ 4, -1, -2, -2, 0, -1, -1, 0, -2, -1, -1, -1, -1, -2, -1, 1, 0, -3, -2, 0],
[-1, 5, 0, -2, -3, 1, 0, -2, 0, -3, -2, 2, -1, -3, -2, -1, -1, -3, -2, -3],
[-2, 0, 6, 1, -3, 0, 0, 0, 1, -3, -3, 0, -2, -3, -2, 1, 0, -4, -2, -3],
[-2, -2, 1, 6, -3, 0, 2, -1, -1, -3, -4, -1, -3, -3, -1, 0, -1, -4, -3, -3],
[ 0, -3, -3, -3, 9, -3, -4, -3, -3, -1, -1, -3, -1, -2, -3, -1, -1, -2, -2, -1],
[-1, 1, 0, 0, -3, 5, 2, -2, 0, -3, -2, 1, 0, -3, -1, 0, -1, -2, -1, -2],
[-1, 0, 0, 2, -4, 2, 5, -2, 0, -3, -3, 1, -2, -3, -1, 0, -1, -3, -2, -2],
[ 0, -2, 0, -1, -3, -2, -2, 6, -2, -4, -4, -2, -3, -3, -2, 0, -2, -2, -3, -3],
[-2, 0, 1, -1, -3, 0, 0, -2, 8, -3, -3, -1, -2, -1, -2, -1, -2, -2, 2, -3],
[-1, -3, -3, -3, -1, -3, -3, -4, -3, 4, 2, -3, 1, 0, -3, -2, -1, -3, -1, 3],
[-1, -2, -3, -4, -1, -2, -3, -4, -3, 2, 4, -2, 2, 0, -3, -2, -1, -2, -1, 1],
[-1, 2, 0, -1, -3, 1, 1, -2, -1, -3, -2, 5, -1, -3, -1, 0, -1, -3, -2, -2],
[-1, -1, -2, -3, -1, 0, -2, -3, -2, 1, 2, -1, 5, 0, -2, -1, -1, -1, -1, 1],
[-2, -3, -3, -3, -2, -3, -3, -3, -1, 0, 0, -3, 0, 6, -4, -2, -2, 1, 3, -1],
[-1, -2, -2, -1, -3, -1, -1, -2, -2, -3, -3, -1, -2, -4, 7, -1, -1, -4, -3, -2],
[ 1, -1, 1, 0, -1, 0, 0, 0, -1, -2, -2, 0, -1, -2, -1, 4, 1, -3, -2, -2],
[ 0, -1, 0, -1, -1, -1, -1, -2, -2, -1, -1, -1, -1, -2, -1, 1, 5, -2, -2, 0],
[-3, -3, -4, -4, -2, -2, -3, -2, -2, -3, -2, -3, -1, 1, -4, -3, -2, 11, 2, -3],
[-2, -2, -2, -3, -2, -1, -2, -3, 2, -1, -1, -2, -1, 3, -3, -2, -2, 2, 7, -1],
[ 0, -3, -3, -3, -1, -2, -2, -3, -3, 3, 1, -2, 1, -1, -2, -2, 0, -3, -1, 4]];
//***blosum62squarematrix
//***Axes***
if ((WhatsClickedSequence.length != 0) && !(AminoAcidProperties[AminoAcidPropertiesCount].match(/^All$|^None$/))) {
//***Y-axis labels
d3.select("#GraphSvg").append("text").text(function() {var array = WhatsClickedSequence; return "More "+array.toString();}).attr("id","YaxisSequence").attr("x",GraphPadding*0.8).attr("y",GraphH*0.25).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {if (WhatsClickedSequence.length <= 5) {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50;}else{return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50*1/Math.sqrt(WhatsClickedSequence.length/5);}}).attr("fill","DodgerBlue").attr("transform",function () {return "rotate(-90 "+String(GraphPadding*0.8)+","+String(GraphH*0.25)+")";});
d3.select("#GraphSvg").append("text").text(function() {if(!(AminoAcidProperties[AminoAcidPropertiesCount].match(/^All$|^None$|^Sequence Display$/))){return "More "+String(AminoAcidProperties[AminoAcidPropertiesCount]);}else if (AminoAcidProperties[AminoAcidPropertiesCount].match(/^Sequence Display$/)){var array = WhatsClicked; return "More "+array.toString();} else {return "";}}).attr("id","YaxisFeature").attr("x",GraphPadding*0.8).attr("y",GraphH*0.75).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {if (!(AminoAcidProperties[AminoAcidPropertiesCount].match(/^Sequence Display$/))) {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50;} else if (WhatsClicked.length <= 5) {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50;} else {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*50*1/Math.sqrt(WhatsClicked.length/5);}}).attr("fill","DodgerBlue").attr("transform",function () {return "rotate(-90 "+String(GraphPadding*0.8)+","+String(GraphH*0.75)+")";});
//***Y-axis labels
//***X-axis scale
d3.select("#GraphSvg")
.selectAll("GraphTickElements")
.data(GraphData)
.enter()
.append("rect")
.attr("x",function(d,i) {
var TickWidth = GraphPadding/10;
return 2*GraphPadding+((GraphW-3*GraphPadding)/GraphData.length)/2+i*((GraphW-3*GraphPadding)/GraphData.length)-TickWidth/2;
})
.attr("y",GraphH/2)
.attr("width",function (d,i) {
var TickWidth = GraphPadding/10;
if (i % 5 == 0) {
return 2*TickWidth;
} else {
return TickWidth;
}
})
.attr("height",function (d,i) {
if (i % 5 == 0) {
return 2*GraphHnew*12/GraphHdefault;
} else {
return GraphHnew*12/GraphHdefault;
}
})
.attr("fill","DimGray");
//***X-axis scale
}
//***Axes***
//***If only one aminoacid is clicked on the sequence and the feature track than this part calculates possible aggreement between graph and blosum62 scores.
if ((WhatsClickedSequence.length == 1) && (WhatsClicked.length == 1) && (String(AminoAcidProperties[AminoAcidPropertiesCount]) == "Sequence Display")) {
//***Score of the single AA->AA substitution from blosum62 matrix***
var Blosum62Value = blosum62[parseInt(AminoacidsSquareMatrixNumber[WhatsClickedSequence[0]])-1][parseInt(AminoacidsSquareMatrixNumber[WhatsClicked[0]])-1];
//***Score of the single AA->AA substitution from blosum62 matrix***
var ColorScale = {"0":"rgb(255,255,204)","1":"rgb(194,230,153)","2":"rgb(120,198,121)","3":"rgb(35,132,67)"};
//***below is agreement value. It is 1 minus the p value times two. 1.65 p value is around 0.05 so it is 1-0.1 = 0.9.
var Zthresholds = {"1.65":"90","1.29":"80","1.04":"70","0.85":"60","0.68":"50","0.53":"40","0.39":"30","0.26":"20","0.13":"10"};
//***Dynamically calculate max and min of the square matrix and linearly map absolute values of log ratios to this range***
var blosum62MinMax = [0,0];
for (var i = 0;i<blosum62.length;i++){
var min = d3.min(blosum62[i]);
var max = d3.max(blosum62[i]);
if (min < blosum62MinMax[0]) {
blosum62MinMax[0] = min;
}
if(max > blosum62MinMax[1]) {
blosum62MinMax[1] = max;
}
}
var LinearMapStep = (blosum62MinMax[1]-blosum62MinMax[0])/3;
var Blosum62AgreementData = [];
for (var i = 0;i<GraphData.length;i++) {
var LinearProjectionLogValue = blosum62MinMax[1] - LinearMapStep*Math.abs(GraphData[i]);
var AgreementQuotient = 3 - Math.abs(LinearProjectionLogValue - Blosum62Value)/LinearMapStep;
//***If the value is smaller than a threshold set by random similarity (7.5(scale of 0 to 15 which corresponds to 1.5 of scale of 0 to 3) in this case, midpoint of 0(no difference) and 15 (max difference)), than the quotient is 0***
if (AgreementQuotient < 3/2) {
AgreementQuotient = 0;
}
//***If the value is smaller than a threshold set by random similarity (7.5(scale of 0 to 15 which corresponds to 1.5 of scale of 0 to 3) in this case, midpoint of 0(no difference) and 15 (max difference)), than the quotient is 0***
Blosum62AgreementData.push(AgreementQuotient);
}
//***Dynamically calculate max and min of the square matrix and linearly map absolute values of log ratios to this range***
//***Draw Agreement Graph***
d3.select("#GraphSvg")
.selectAll("GraphLineBlosum62Elements")
.data(Blosum62AgreementData)
.enter()
.append("path")
.attr("d",function (d,i) {
var x = 2*GraphPadding+((GraphW-3*GraphPadding)/Blosum62AgreementData.length)/2+i*((GraphW-3*GraphPadding)/Blosum62AgreementData.length);
var y = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(d-3);
return "M "+String(x)+","+String(y)+" L "+String(x)+","+String(y);
})
.attr("stroke",function(d,i) {return ColorScale[String(parseInt(d))];})
.attr("stroke-width",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*12;})
.attr("class","GraphBlosum62Lines")
.on("mouseover",function(d,i) {
d3.select("#Blosum62Window").remove();
d3.select("#Blosum62PvalueIndicator").remove();
d3.select("#GraphSvg")
.append("rect")
.attr("x",function() {return 2*GraphPadding+((GraphW-3*GraphPadding)/Blosum62AgreementData.length)/2+i*((GraphW-3*GraphPadding)/Blosum62AgreementData.length);})
.attr("y",GraphPadding)
.attr("width",function() {return ((GraphW-3*GraphPadding)/Blosum62AgreementData.length);})
.attr("height",function() {return GraphH-2*GraphPadding;})
.attr("fill",function() {return ColorScale[String(parseInt(d))];})
.attr("fill-opacity",0.5)
.attr("id","Blosum62Window")
.on("mouseover",function() {
var thresholds = d3.keys(Zthresholds).sort(d3.descending);
var p_value;
for (var i = 0;i<thresholds.length;i++) {
var StandardDeviation = 0.5;
var Mean = 1.5;
var DistanceToMean =(d-Mean)/StandardDeviation;
if (parseFloat(thresholds[i])<DistanceToMean) {
p_value = (100-Zthresholds[thresholds[i]])/200;
break;
}
if((i == thresholds.length - 1) && (p_value === undefined)) {
p_value = "insignificant";
}
}
d3.select("#GraphSvg").append("text").text(function() {return "Blosum62 agreement score: "+String(d.toFixed(2))+",p-value<="+String(p_value);}).attr("id","Blosum62PvalueIndicator").attr("x",function() {return GraphWnew/2;}).attr("y",function() {if (d >= 0) {return GraphHnew*4/5;} else {return GraphHnew*1/5;}}).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*80;}).attr("fill","DarkSalmon").attr("fill-opacity",0.8);
})
.on("mouseout",function() {
d3.select("#Blosum62Window").remove();
d3.select("#Blosum62PvalueIndicator").remove();
});
});
d3.selectAll(".GraphBlosum62Lines").data(Blosum62AgreementData).each(function(d,i) {
d3.select(this)
.transition()
.attr("d", function (){
if (i != Blosum62AgreementData.length-1) {
var x = 2*GraphPadding+((GraphW-3*GraphPadding)/Blosum62AgreementData.length)/2+i*((GraphW-3*GraphPadding)/Blosum62AgreementData.length);
var y = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(d-3);
var x_prime = 2*GraphPadding+((GraphW-3*GraphPadding)/Blosum62AgreementData.length)/2+(i+1)*((GraphW-3*GraphPadding)/Blosum62AgreementData.length);
var y_prime = GraphPadding+(GraphH-2*GraphPadding)/6*Math.abs(Blosum62AgreementData[i+1]-3);
return "M "+String(x)+","+String(y)+" L "+String(x_prime)+","+String(y_prime);
}
})
.delay(function () {
var RenderLength = parseFloat((2500/(Blosum62AgreementData.length-1)).toFixed(0));
return i*RenderLength;
})
.duration(function () {
var RenderLength = parseFloat((2500/(Blosum62AgreementData.length-1)).toFixed(0));
return RenderLength;
});
});
//***Draw Agreement Graph***
//***Incase of AA->AA change give options to hide either of two graphs
d3.select("#GraphSvg").append("text").text("hide Blosum62").attr("id","hideBlosum62").attr("x",GraphW*0.33).attr("y",GraphH-GraphPadding*0.2).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*45;}).attr("fill","DodgerBlue")
.on("mouseover", function() {
d3.select("#hideBlosum62").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function() {
d3.select("#hideBlosum62").transition().attr("fill","DodgerBlue").delay(0).duration(250);
})
.on("click", function() {
d3.select("#hideBlosum62").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#showBlosum62").transition().attr("visibility","visible").delay(0).duration(0);
d3.selectAll(".GraphBlosum62Lines").transition().attr("visibility","hidden").delay(0).duration(0);
});
d3.select("#GraphSvg").append("text").text("show Blosum62").attr("id","showBlosum62").attr("x",GraphW*0.33).attr("y",GraphH-GraphPadding*0.2).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*45;}).attr("fill","DodgerBlue").attr("visibility","hidden")
.on("mouseover", function() {
d3.select("#showBlosum62").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function() {
d3.select("#showBlosum62").transition().attr("fill","DodgerBlue").delay(0).duration(250);
})
.on("click", function() {
d3.select("#showBlosum62").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#hideBlosum62").transition().attr("visibility","visible").delay(0).duration(0);
d3.selectAll(".GraphBlosum62Lines").transition().attr("visibility","visible").delay(0).duration(0);
});
d3.select("#GraphSvg").append("text").text("hide LogPlot").attr("id","hideLogPlot").attr("x",GraphW*0.66).attr("y",GraphH-GraphPadding*0.2).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*45;}).attr("fill","DodgerBlue")
.on("mouseover", function() {
d3.select("#hideLogPlot").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function() {
d3.select("#hideLogPlot").transition().attr("fill","DodgerBlue").delay(0).duration(250);
})
.on("click", function() {
d3.select("#hideLogPlot").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#showLogPlot").transition().attr("visibility","visible").delay(0).duration(0);
d3.selectAll(".GraphLines").transition().attr("visibility","hidden").delay(0).duration(0);
});
d3.select("#GraphSvg").append("text").text("show LogPlot").attr("id","showLogPlot").attr("x",GraphW*0.66).attr("y",GraphH-GraphPadding*0.2).attr("text-anchor","middle").attr("font-family","Arial").attr("font-size",function () {return Math.sqrt((GraphWnew*GraphHnew)/(GraphWdefault*GraphWdefault))*45;}).attr("fill","DodgerBlue").attr("visibility","hidden")
.on("mouseover", function() {
d3.select("#showLogPlot").transition().attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function() {
d3.select("#showLogPlot").transition().attr("fill","DodgerBlue").delay(0).duration(250);
})
.on("click", function() {
d3.select("#showLogPlot").transition().attr("visibility","hidden").delay(0).duration(0);
d3.select("#hideLogPlot").transition().attr("visibility","visible").delay(0).duration(0);
d3.selectAll(".GraphLines").transition().attr("visibility","visible").delay(0).duration(0);
});
//***Incase of AA->AA change give options to hide either of two graphs
}
//***If only one aminoacid is clicked on the sequence and the feature track than this part calculates possible aggreement between graph and blosum62 scores.
}
//This one is for sequence/SNV/connector neon affect.
//The function below is called (not from d3, that makes the arguments complicated) for ids["seq"], ids["mut"] and ids["connector"]. You give 1 argument, the id of the element and it return what kind of text shadow it shall get.
//declare a global variable that I will later design some illustration for user control:
var NeonizeMe = 1;
//***Add a global controller where the user can choose to turn on/off Neon Effect***
var neonEffect= "On";
d3.select("#annotation").append("text").text(function() {return "Neon "+neonEffect;}).attr("x",5950).attr("y",375).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","middle").style("fill","DimGray").attr("id","neonEffect")
.on("mouseover",function () {
d3.select("#neonEffect").style("fill","Orange");
})
.on("mouseout",function () {
d3.select("#neonEffect").style("fill","DimGray");
})
.on("click",function () {
d3.select("#neonEffect").transition().attr("fill-opacity",0).each("end",function() {
if (neonEffect == "On") {
neonEffect = "Off";
NeonizeMe = 0;
} else {
neonEffect = "On";
NeonizeMe = 1;
}
document.getElementById("neonEffect").textContent = "Neon "+neonEffect;
d3.select("#neonEffect").transition().attr("fill-opacity",1.0).delay(0).duration(500);
}).delay(0).duration(500);
});
//***Add a global controller above where the user can choose to turn on/off Neon Effect***
function Neonizer() {
if ((NeonizeMe == 1) && !(d3.select(arguments[0]).style("fill") === "none")) {
if(String(arguments[0]).match(/rsID|connector/ig)) {
var rgb = d3.select(arguments[0]).style("fill");
rgb = !(rgb.match(/#/g)) ? rgb : convertHexToRgb(rgb);
rgb = rgb.replace(/rgb\(|\)/ig,"");
return "0px 0px 15px "+String("rgba("+rgb+", 1)")+",0px 0px 2px rgba(255,250,250,0.6),0 0 10px "+String("rgba("+rgb+", 1)")+",0px 0px 16px "+String("rgba("+rgb+", 1)")+",0px 0px 43px "+String("rgba("+rgb+", 1)")+",0px 0px 69px "+String("rgba("+rgb+", 1)")+",0px 0px 111px "+String("rgba("+rgb+", 1)");
} else {
var rgb = d3.select(arguments[0]).style("fill");
rgb = !(rgb.match(/#/g)) ? rgb : convertHexToRgb(rgb);
rgb = rgb.replace(/rgb\(|\)/ig,"");
return "0px 0px 10px "+String("rgba("+rgb+", 0.8)")+",0px 0px 3px white,0px 0px 5px white,0px 0px 8px white,0px 0px 10px "+String("rgba("+rgb+", 1)")+",0px 0px 18px "+String("rgba("+rgb+", 0.9)")+",0px 0px 25px "+String("rgba("+rgb+", 0.7)")+",0px 0px 38px "+String("rgba("+rgb+", 0.6)");
}
} else {
return "none";
}
}
function convertHexToRgb (hex) {
hex = hex.replace("#","");
var r = parseInt(hex.slice(0,2),16);
var g = parseInt(hex.slice(2,4),16);
var b = parseInt(hex.slice(4,6),16);
return "rgb("+r+", "+g+", "+b+")";
}
//The function above is called (not from d3, that makes the arguments complicated) for ids["seq"], ids["mut"] and ids["connector"]. You give 1 argument, the id of the element and it return what kind of text shadow it shall get.
<!--Prediction Related Stuff-->
//***Add a global controller where the user can choose to color/figure code SNV predictions***
var colorCoding= "On";
d3.select("#annotation").append("text").text(function() {return "Color-coding "+colorCoding;}).attr("x",5950).attr("y",275).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","middle").style("fill","DimGray").attr("id","colorCoding")
.on("mouseover",function () {
d3.select("#colorCoding").style("fill","Orange");
})
.on("mouseout",function () {
d3.select("#colorCoding").style("fill","DimGray");
})
.on("click",function () {
d3.select("#colorCoding").transition().attr("fill-opacity",0).each("end",function() {
if (colorCoding == "On") {
colorCoding = "Color-blind";
} else {
colorCoding = "On";
}
document.getElementById("colorCoding").textContent = "Color-coding "+colorCoding;
d3.select("#colorCoding").transition().attr("fill-opacity",1.0).delay(0).duration(500);
}).delay(0).duration(500);
});
//***Add a global controller above where the user can choose to color/figure code SNV predictions***
//***this is the database hash: the array has the keyword and the threshold for deleteriousness***
var predictionDatabase = {"1":["polyphen2","0.85"],"2":["sift","0.05","inverse"]};
var logoAngelAltCb = "data:image/png;base64,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";
var logoAngelAlt ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAGgAAAAeCAYAAADAZ1t9AAAABHNCSVQICAgIfAhkiAAAAAlwSFlzAAADEwAAAxMBPWaDxwAAABl0RVh0U29mdHdhcmUAd3d3Lmlua3NjYXBlLm9yZ5vuPBoAAAbGSURBVGiB7Zp5jFRFEIe/wl1RDhHFAySoRDEeiKhgxOgqSlA0isaYeICBmOAdRRA0atNGooHgFaMJIQjGg3groiSCRhGDcogXh3igogFWEUauFdbyj36DPb39Zt/Ozrqo+0s6ma6urq559bq6qvoJ49hI/dgB5Ly2HJisRpdkmLtbQazcDdzmkb5Woyc3lz71oQLokJG3k/f7DGCEWJkDDFajW8quWdNhLwr/8z7NpUgWtGrk/HOAl8RKZTmUaUFdxAz0B7ApaTlgC1AD1KbIGAiMaRLtWkBFhPasGh0WYxYr3YHRwLXB0BDgvjLr1lR4DHjB629vLkWyQBiHBrRpaQbaNcnKIuAkj1QL7K1Gd5Rbwf87YjsoC96m0EA7SXeBAIiVi3HBxYlAD2AjsAx4DXguzbhiZV9grEfarkbHJWP9gGuAPkBH4AtgMTBVjX6TIm8gcJZHqlajk4ro3R+4IFmjO7AGeBN4Qo2uFyvnA6d7U95To2958zsAd3jjNWrUJGOnJvr3TdO/1B20EPBD04VqtG8Kb0dgCnBJEZFfAVeq0UWR+d2A7z1SDtgfeBS4LkXeJmC4Gn05Im88cKdHWqVGe0T4KoH7gZGARNZYB1wGXJTw5DFRjd7uyekK/OiNb8YZ42HghhT9c4n+LzUoihMr+4iVsRQaB9zDivF3B5ZS3DjgdtRcsZIlHxFgOunGARdGvyBWjsggr+4CVvYA3sLlSzHjABwEzAJ6N1Q88CTpxgEX+j8vVnrEXNwAsTLb61ckrRI4lrp504vAM3W0cH9yBtAtGJoHzAe6Apfi8pK8Us+KlRPU6NYiyrcHrkh+rwHeSOYOAvb1+FrhApoRRWSlYRRwdkDbkay1HDgaOB9oR6G7zIK2wFXJ75+Ambj/NAi3s/JoBYyOGeiQpNWHWmACcK8aDd0kwGCc3/YxUo0+lO+IlQeAD/j7wR6ZKD85w/oPqdFdrkWs9AI+Alp7PKdkkFOAxLXdEpBzwAVqdJ7Hdxru4XakNDwC3Jp/dmLleOBjAv0bk6juAVTh8qAYwnNsvm8cADX6Jc7IPoZmWHsJQe6lRj/FBRw+DsggK0Q/4OCANsk3TrLefGB8CfIBPgFG+y+2Gv0MeCXgO6CxlYR+wKti5R6fKFYEOC3gnZMiI6T3yVCZmJMS9a0P+qUYKBbspO3oJ6gnek3B3Iz6d4q5uFcojHIEd/60BjoDZwI343ZQHlasLFWjryf9Ayk8DwD6i5XwzQTYO+jvCRyFCznTsC6FXh30K8WKpLjgNHQN+tvU6NoYoxrdKlbWku1I8JFV/4qYgTap0RVFhL8uVmYC7wR0A+QNFBoHXK5weoQeQ6d6xtP+4K8Z5RdDWDwNH1pMl3IZqI7+Jbk4Nfou8HlA7i1W8rthWylyPbSpZzztoZWjkvFb0K/vZSnFjWbWv9RKAsA3QE+vL7iQeiUu/N2Bc415jAGezyg79MUhmrKk9H3QbyNW9lejdd5usdKahu8eaID+JRko2SkDIkPVAGr0T7HyI640ksd+anR1RFYlsLOB50RTYnWENgSX+YcYRuOvbIqiwcLFyoHA47iEy8cqNbrB688LxoeKlfYRkdOBnFhZIFamiJWbkiiwuTAH2BDQxoqVgnKQWDkOd+42KWI7qEqszAhorXHZbjtcNaFdZN60oD8Bl9PkH3ZnYIZYGZp3F2LlQuDyZPyUpD3VnLtJjW4RK48Dd3nkg4AFYmUqrm7YExhO/WdloxEz0OFJawhWAg/6BDW6TKy8ClzskQcBP4iVpTjffWggpwawDVy7KfAozgBdPFpHCr9lABcM1RCPWsuCcvjPb4Hz1Gjs4ms4rljqow0uwY0ZZ7Aa/bYMOjUKarQauBD4pQhbDW73/xxOL6cupRpIgRU4H9xbjX4XZTK6EXcHNAl3lZ6GD4EBanR2EZ5/FGp0MdALeJrCtEFx92F91GhYWgL3iUDZUEHxaqziLuO2496YfNuoRnNZFlCjvwOjxMq9wLnAMTifvhkXMS1WowuKiFgX0THclXnMxJ0R/vrhGz0F94DzSK2cq9GfgSFiZQRwGO7sXa1G/TQgTGw3B/1qsus/K+QV3W2i290DYqUtMBH38uxqgVHyvK1wnsEve12uRsMgq2Q0JlH9r2Ib7sqjICUQK33V6MKA91oKjQPpu6MktOygCMTKXKB/QP4Bd2G3FDgC921FFYXVkvfVaFU5dWnZQXHcCbxH4eVZN+D6InNqgRvLrUiTlin+rVCjHwFXk706vha4Wo2GBeRGo8XFFYFYaYPL5S7CJdZd+PubjBzuzmo27vo9jN7Kgr8AMsYdgqYmRIYAAAAASUVORK5CYII=";
var logoDemonAlt ="data:image/png;base64,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";
//Supply 2 arguments, 1: the database hash, 2: the id of the element
function returnPredictionScores() {
var argument0 = arguments[0];
var argument1 = arguments[1];
//alert (arguments[0][String(1)][0]+","+arguments[1]+","+String(argument0)+","+String(argument1)+","+argument0[String(1)][0]);
for (var i = 1;i <= d3.keys(argument0).length;i++) {
d3.select("#annotation")
.append("text")
.text(function(){
var prediction = "";
var keyword = argument0[String(i)][0];
if(d3.select(argument1).attr(keyword).match(/^\s*[0-9]+[.]?[0-9]*\s*$/)) {
var predictionScore = parseFloat(d3.select(argument1).attr(keyword));
var benignOrDeleterious ;
if((argument0[String(i)][2] !== undefined)&&(argument0[String(i)][2].match(/inverse/i))) {
if (predictionScore > parseFloat(argument0[String(i)][1])) {
angelOrDemon("angel",i);
} else {
angelOrDemon("demon",i);
}
} else {
if (predictionScore < parseFloat(argument0[String(i)][1])) {
angelOrDemon("angel",i);
} else {
angelOrDemon("demon",i);
}
}
prediction = String(prediction)+argument0[String(i)][0]+" score: "+predictionScore.toFixed(2);
}
return prediction;
})
.attr("class","text2")
.attr("text-anchor","middle")
.attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-500;} else {return coordinates[0]+500;}})
.attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-200+i*250;} else {return coordinates[1]+200+i*250;}})
.attr("font-family","sans-serif")
.attr("font-size","100px")
.attr("fill","Orange")
.attr("stroke","Orange")
.attr("fill-opacity",0.0)
.attr("stroke-opacity",0.0)
.attr("visibility","visible")
}
}
//Supply 1:angel or demon, 2: the number of the prediction algorithm
//The logos has to be placed a bit right of the normal x coordinate and at the same y coordinate of the prediction text
function angelOrDemon () {
//alert(arguments[0]+","+arguments[1]);
var argument1 = arguments[1];
if (arguments[0].match(/angel/i)) {
d3.select("#annotation").append("svg:image").attr("xlink:href",function(){if(colorCoding.match(/on/i)){return logoAngelAlt;}else{return logoAngelAltCb;}}).attr("title","benign").attr("alt","benign").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]+50;} else {return coordinates[0]+1050;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-75+(parseInt(argument1)-1)*250;} else {return coordinates[1]+325+(parseInt(argument1)-1)*250;}}).attr("width","300px").attr("height","200px").attr("fill-opacity",0).style("opacity",0).attr("class","text2");
} else {
d3.select("#annotation").append("svg:image").attr("xlink:href",logoDemonAlt).attr("title","deleterious").attr("alt","deleterious").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]+50;} else {return coordinates[0]+1050;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-145+(parseInt(argument1)-1)*255;} else {return coordinates[1]+255+(parseInt(argument1)-1)*255;}}).attr("width","480px").attr("height","320px").attr("fill-opacity",0).style("opacity",0).attr("class","text2");
}
}
<!--Prediction Related Stuff-->
<!--Some unnecessary geek stuff -->
var ipvWatchOnOff = 0;
var currentTime;
var currentHourDial;
var currentSecondDial;
var ipvWatch = "data:image/png;base64,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";
d3.select("#annotation").append("svg:image").attr("xlink:href",ipvWatch).attr("title","ipvWatch").attr("alt","ipvWatch").attr("x",5550).attr("y",200).attr("width","100px").attr("height","100px").style("opacity",0.62).attr("id","ipvWatchIcon");
d3.select("#ipvWatchIcon")
.on("mouseover", function () {
d3.select(this).style("opacity",1);
})
.on("mouseout", function () {
d3.select(this).style("opacity",0.62);
})
.on("click",function () {
if (ipvWatchOnOff == 0) {
openWatch();
ipvWatchOnOff = 1;
//hide overview tabs
hideOrshowhtmlElements("0",false,true);
} else {
clearInterval(currentTime);
clearInterval(currentHourDial);
clearInterval(currentSecondDial);
d3.selectAll(".geekWatch").remove();
ipvWatchOnOff = 0;
//hide overview tabs
hideOrshowhtmlElements("1",false,true);
}
});
function openWatch() {
var date;
var time;
currentTime = setInterval(function () {
d3.select("#ipvWatch").remove();
d3.select("#annotation").append("text").text(timeFunction()).attr("x",3000).attr("y",3350).style("font-family","Consolas,Monaco,Lucida Console,Liberation Mono,DejaVu Sans Mono,Bitstream Vera Sans Mono,Courier New").style("font-size","90px").attr("text-anchor","middle").attr("fill","Lime").attr("id","ipvWatch").attr("class","geekWatch");
},1000);
d3.select("#annotation").append("circle").attr("r",424).attr("cx",3000).attr("cy",3350).attr("fill-opacity",0).attr("fill","DeepPink").attr("stroke","DeepPink").attr("stroke-opacity",0.62).attr("stroke-width","28px").attr("class","geekWatch");
d3.select("#annotation").append("path").attr("d","M 3000,2926 L 3000,1600").attr("stroke-width","14px").attr("stroke","DeepPink").attr("stroke-opacity",0.62).attr("id","ipvHourDial").attr("class","geekWatch");
d3.select("#annotation").append("circle").attr("r",400).attr("cx",3000).attr("cy",3350).attr("fill-opacity",0).attr("fill","Orange").attr("stroke","Orange").attr("stroke-opacity",0.62).attr("stroke-width","20px").attr("class","geekWatch");
d3.select("#annotation").append("path").attr("d","M 3000,2950 L 3000,750").attr("stroke-width","10px").attr("stroke","Orange").attr("stroke-opacity",0.62).attr("id","ipvSecondDial").attr("class","geekWatch");
currentHourDial = setInterval(function () {
d3.select("#ipvHourDial").transition().attr("d",function() {var xPrime = 3000+(424+28/2-1)*Math.cos(watch("hour")); var yPrime = 3350-(424+28/2-1)*Math.sin(watch("hour")); var x = 3000+1400*Math.cos(watch("hour")); var y = 3000-1400*Math.sin(watch("hour")); return "M "+String(xPrime)+","+String(yPrime)+" L "+String(x)+","+String(y);}).delay(0).duration(618);
},1000);
currentSecondDial = setInterval(function () {
d3.select("#ipvSecondDial").transition().attr("d",function() {var xPrime = 3000+(400+20/2-1)*Math.cos(watch("default")); var yPrime = 3350-(400+20/2-1)*Math.sin(watch("default")); var x = 3000+2250*Math.cos(watch("default")); var y = 3000-2250*Math.sin(watch("default")); return "M "+String(xPrime)+","+String(yPrime)+" L "+String(x)+","+String(y);}).delay(0).duration(618);
},1000);
function timeFunction() {
date = new Date();
time = date.toLocaleTimeString();
return time;
}
function watch() {
var angle = parseInt(time.split(/:|\s/)[2]);
/*if (angle == 0) {
angle = 60;
}*/
if (arguments[0].match(/seconds/)){
return angle;
} else {
if (arguments[0].match(/hour/)) {
var minutes = parseInt(time.split(/:|\s/)[1]);
var hours = parseInt(time.split(/:|\s/)[0]);
var totalSeconds = minutes*60+angle;
var angleHour = totalSeconds/3600*30+hours*30;
angleHour = angleHour/360*2*Math.PI;
angleHour = Math.PI/2-angleHour;
return angleHour;
} else {
angle = 6*angle;
angle = angle/360*2*Math.PI;
angle = Math.PI/2-angle;
return angle;
}
}
}
}
<!--Some unnecessary geek stuff -->
<!--Drag mechanism -->
//Global Drag variables that will be automatically refreshed for each new draggable element
var dragOffsetX = 0;
var dragOffsetY = 0;
var dragX = 0;
var dragY = 0;
//Global Drag variables that will be automatically refreshed for each new draggable element
//Supply the drag event handler and also the id of the element to be operated on.
function dragStart(event) {
//alert(event.target.id);--> Check for bubbling
dragX = parseFloat(event.pageX)*4.67-500;
dragY = parseFloat(event.pageY)*4;
dragOffsetX = dragX-parseFloat(d3.select(arguments[1]).attr("x"));
dragOffsetY = dragY-parseFloat(d3.select(arguments[1]).attr("y"));
}
//Supply the drag event handler and also the id of the element to be operated on.
function dragMe(event) {
dragX = parseFloat(event.pageX)*4.67-500;
dragY = parseFloat(event.pageY)*4;
d3.select(arguments[1]).attr("x",function () {return dragX-dragOffsetX}).attr("y",function() {return dragY-dragOffsetY});
}
//Supply the drag event handler and also the id of the element to be operated on.
//below function will have to be modified at some point if I add new draggable elements since it also sets GrapNewLocation array.
function dragEnd(event) {
dragX = parseFloat(event.pageX)*4.67-500;
dragY = parseFloat(event.pageY)*4;
d3.select(arguments[1]).attr("x",function () {GraphNewLocation[0] = dragX-dragOffsetX; return dragX-dragOffsetX}).attr("y",function() {GraphNewLocation[1] = dragY-dragOffsetY; return dragY-dragOffsetY});
}
<!--Drag mechanism -->
<!--A new Tab #2: Mark Tab -->
var htmlDivIdCounter = -1;
var markCounter = 0;
var inputBackgroundColor = "rgba(255,165,0,0.4)";
var overviewTabArray = [{"id":"OverviewLength"},{"id":"OverviewMark"}];
var markHash = {};
//Inserts a single input box at the specified left and top style values. The center of the input box is aligned with the style value.
function insertInput() {
var inputHash;
eval('inputHash = '+ arguments[0]);
if((inputHash["flushCounter"] !== undefined)&&(inputHash["flushCounter"].match(/yes/i))) {
htmlDivIdCounter = -1;
}
if(inputHash["prefix"] === undefined) {
inputHash["prefix"] = "default";
}
htmlDivIdCounter++;
d3.select(document.body).append("div").attr("id",function() {return inputHash["prefix"]+"htmlDiv"+htmlDivIdCounter;}).attr("class",inputHash["class"]).attr("style",function () {return 'position:absolute;'+'top:'+(parseFloat(inputHash["top"])-parseFloat(inputHash["height"])/2)+'px;left:'+(parseFloat(inputHash["left"])-parseFloat(inputHash["width"])/2)+'px;height:'+inputHash["height"]+';width:'+inputHash["width"]+';background:transparent;'});
d3.select("#"+inputHash["prefix"]+"htmlDiv"+htmlDivIdCounter).append("div:form").attr("style",function() {return 'position:absolute;top:0px;left:0px;height:'+inputHash["height"]+';width:'+inputHash["width"]+';background:transparent';}).attr("id",function() {return inputHash["prefix"]+"htmlForm"+htmlDivIdCounter;}).attr("class",inputHash["class"]);
if(inputHash["check"] === "number") {
d3.select("#"+inputHash["prefix"]+"htmlForm"+htmlDivIdCounter).append("form:input").attr("id",function() {return inputHash["prefix"]+"htmlInput"+htmlDivIdCounter;}).attr("class",function () {return inputHash["class"]+"Inputs";}).attr("type","text").attr("style",function () {if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)) {inputBackgroundColor = "rgba(30,144,255,0.4)";} else {inputBackgroundColor = "rgba(255,165,0,0.4)";};return 'position:absolute;margin:0px;top:'+(parseFloat(inputHash["height"])*0.1)+'px;left:0px;height:'+(parseFloat(inputHash["height"])*0.8-4)+'px;padding:0px;width:'+(parseFloat(inputHash["width"])-4)+'px;background:'+inputBackgroundColor+';border-radius:5px;border-width:2px;border-color:rgba(105,105,105,0.6);border-style:solid;color:NavajoWhite;outline:none;font-family:Consolas,Monaco,Lucida Console,Liberation Mono,DejaVu Sans Mono,Bitstream Vera Sans Mono,Courier New;font-weight:bold;'}).attr("onfocus",function () {return "inputFocus('"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"')"}).attr("onblur",function () {return "inputCheckNumber("+"'"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"'"+",'number'"+")";});
} else if(inputHash["check"] === "radius") {
d3.select("#"+inputHash["prefix"]+"htmlForm"+htmlDivIdCounter).append("form:input").attr("id",function() {return inputHash["prefix"]+"htmlInput"+htmlDivIdCounter;}).attr("class",function () {return inputHash["class"]+"Inputs";}).attr("type","text").attr("style",function () {if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)) {inputBackgroundColor = "rgba(30,144,255,0.4)";} else {inputBackgroundColor = "rgba(255,165,0,0.4)";};return 'position:absolute;margin:0px;top:'+(parseFloat(inputHash["height"])*0.1)+'px;left:0px;height:'+(parseFloat(inputHash["height"])*0.8-4)+'px;padding:0px;width:'+(parseFloat(inputHash["width"])-4)+'px;background:'+inputBackgroundColor+';border-radius:5px;border-width:2px;border-color:rgba(105,105,105,0.6);border-style:solid;color:NavajoWhite;outline:none;font-family:Consolas,Monaco,Lucida Console,Liberation Mono,DejaVu Sans Mono,Bitstream Vera Sans Mono,Courier New;font-weight:bold;'}).attr("onfocus",function () {return "inputFocus('"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"')"}).attr("onblur",function () {return "inputCheckNumber("+"'"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"'"+",'radius'"+")";});
} else if (inputHash["check"] === "color"){
d3.select("#"+inputHash["prefix"]+"htmlForm"+htmlDivIdCounter).append("form:input").attr("id",function() {return inputHash["prefix"]+"htmlInput"+htmlDivIdCounter;}).attr("class",function () {return inputHash["class"]+"Inputs";}).attr("type","text").attr("style",function () {if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)) {inputBackgroundColor = "rgba(30,144,255,0.4)";} else {inputBackgroundColor = "rgba(255,165,0,0.4)";};return 'position:absolute;margin:0px;top:'+(parseFloat(inputHash["height"])*0.1)+'px;left:0px;height:'+(parseFloat(inputHash["height"])*0.8-4)+'px;padding:0px;width:'+(parseFloat(inputHash["width"])-4)+'px;background:'+inputBackgroundColor+';border-radius:5px;border-width:2px;border-color:rgba(105,105,105,0.6);border-style:solid;color:NavajoWhite;outline:none;font-family:Consolas,Monaco,Lucida Console,Liberation Mono,DejaVu Sans Mono,Bitstream Vera Sans Mono,Courier New;font-weight:bold;'}).attr("onfocus",function () {return "inputFocus('"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"')"}).attr("onblur",function () {return "inputCheckColor("+"'"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"'"+")";});
} else {
d3.select("#"+inputHash["prefix"]+"htmlForm"+htmlDivIdCounter).append("form:input").attr("id",function() {return inputHash["prefix"]+"htmlInput"+htmlDivIdCounter;}).attr("class",function () {return inputHash["class"]+"Inputs";}).attr("type","text").attr("style",function () {if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)) {inputBackgroundColor = "rgba(30,144,255,0.4)";} else {inputBackgroundColor = "rgba(255,165,0,0.4)";};return 'position:absolute;margin:0px;top:'+(parseFloat(inputHash["height"])*0.1)+'px;left:0px;height:'+(parseFloat(inputHash["height"])*0.8-4)+'px;padding:0px;width:'+(parseFloat(inputHash["width"])-4)+'px;background:'+inputBackgroundColor+';border-radius:5px;border-width:2px;border-color:rgba(105,105,105,0.6);border-style:solid;color:NavajoWhite;outline:none;font-family:Consolas,Monaco,Lucida Console,Liberation Mono,DejaVu Sans Mono,Bitstream Vera Sans Mono,Courier New;font-weight:bold;'}).attr("onfocus",function () {return "inputFocus('"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"')"}).attr("onblur",function () {return "inputBlur('"+inputHash["prefix"]+"htmlInput"+htmlDivIdCounter+"')"});
}
}
//Inserts a single input box at the specified left and top style values. The center of the input box is aligned with the style value.
//Check number
function inputCheckNumber() {
var ID = arguments[0];
inputBlur(ID);
if (!(isNaN(parseFloat(document.getElementById(ID).value)))) {
if (arguments[1].match(/number/i)) {
if(document.getElementById(ID).value.match(/[a-z]+/i)) {
document.getElementById(ID).value = "";
alert ("no letters!");
return 0;
} else if (parseFloat(document.getElementById(ID).value) < 0.5) {
document.getElementById(ID).value = "0.5";
alert ("minimum value is 0.5!");
return 0;
} else if (parseInt(document.getElementById(ID).value) > fasta_sorted.length) {
document.getElementById(ID).value = String(fasta_sorted.length);
alert ("maximum is protein length!");
return 0;
} else {
return 1;
}
} else if (arguments[1].match(/radius/i)) {
if ((parseFloat(document.getElementById(ID).value).toFixed(3)) < 0.38) {
document.getElementById(ID).value = "0.38";
alert ("radius can't be smaller than 0.38!");
return 0;
} else if ((parseFloat(document.getElementById(ID).value).toFixed(3)) > 1.07) {
document.getElementById(ID).value = "1.070";
alert ("maximum is 1.07 radius!");
return 0;
} else {
return 1;
}
}
} else if (document.getElementById(ID).value !== "") {
document.getElementById(ID).value = "";
alert ("numbers only!");
return 0;
}
}
//Check number
//Check color
function inputCheckColor() {
var ID = arguments[0];
inputBlur(ID);
if(document.getElementById(ID).value.match(/^\s*[a-z]+\s*$|^\s*[a-z]+\s*[,;]\s*(1|1[.]0|0[.][0-9]+|0)\s*$|^\s*rgb[a]?\s*\(\s*[1-9]?[0-9]?[0-9]{1}\s*[,]\s*[1-9]?[0-9]?[0-9]{1}\s*[,]\s*[1-9]?[0-9]?[0-9]{1}\s*([,]1|[,]1[.]0|[,]0[.][0-9]+)?\)\s*$/i)) {
return 1;
} else if (document.getElementById(ID).value !== "") {
document.getElementById(ID).value = "";
alert ("I don't get this color :(");
return 0;
}
}
//Check color
//***GLOBAL TAB CONTROLLER***
//The conditional in this function is very important. Argument0 designates either show or hide. Argument1 is master control that bypasses other conditionals, provide anything that translates to true for immunity. Argument2 is sub-master control that bypasses all conditions except the rightmost one, usage same as the previous one.
function hideOrshowhtmlElements () {
if (arguments[0].match(/0/ig)) {
if (arguments[1] || ((arguments[2] || ((arguments[3]||(((ExtractionPane == "open")||(MarkPane == "open"))&& (optionStatus == "open")))&&(ipvWatchOnOff == 0)))&&(R_Click == 0))) {
d3.selectAll(".htmlElements").style("opacity",0).style("visibility","hidden");
d3.selectAll(".DropDownRectMark").style("opacity",0).style("visibility","hidden");
d3.selectAll(".DropDownRectExtract").style("opacity",0).style("visibility","hidden");
}
} else {
if (arguments[1] || ((arguments[2] || ((arguments[3]||(((ExtractionPane == "open")||(MarkPane == "open"))&& (optionStatus == "open")))&&(ipvWatchOnOff == 0)))&&(R_Click == 0))) {
d3.selectAll(".htmlElements").style("opacity",1).style("visibility","visible");
d3.selectAll(".DropDownRectMark").style("opacity",1).style("visibility","visible");
d3.selectAll(".DropDownRectExtract").style("opacity",1).style("visibility","visible");
}
}
}
//***GLOBAL TAB CONTROLLER***
//This is the actual function that inserts a highlight element. Provide an object from the markHash with name,start,end,r1,r2 and color
var minimizeHighlightIcon = "data:image/png;base64,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";
var closeHighlightIcon = "data:image/png;base64,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";
var minimizeHighlightIconOrange = "data:image/png;base64,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";
var closeHighlightIconOrange = "data:image/png;base64,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";
var highlightGradualFade;
var lastMouseoverMarkElementID;
var highlightTopRound = false;
var highlightBottomRound = false;
//refer to File API section to see how below value is changed.
var captureClass = "";
function residuesToHighlight () {
var textDescription = String(arguments[0][0]);
var start = parseFloat(arguments[0][1])-1;
var end = parseFloat(arguments[0][2])-1;
var r1 = parseFloat(arguments[0][3])*3000;
var r2 = parseFloat(arguments[0][4])*3000;
var color = String(arguments[0][5]);
var opacity;
if (color.split(/[,;]/g).length > 3) {
opacity = parseFloat(color.split(/[,;]/g)[3]);
} else if (color.split(/[,;]/g).length === 2) {
opacity = parseFloat(color.split(/[,;]/g)[1]);
color = String(color.split(/[,;]/g)[0]);
} else {
opacity = 0.5;
}
//***Minimize/Close Icon coordinates***
var startMinimize = ((start+end)/2-(5/360*fasta_sorted.length)/2);
var rotationMinimize = startMinimize/fasta_sorted.length*360;
var startClose = ((start+end)/2+(5/360*fasta_sorted.length)/2);
var rotationClose = startClose/fasta_sorted.length*360;
var rMinMaxIcon = (r1+r2)/2;
var PointMinimize = [parseInt(3000+rMinMaxIcon*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*startMinimize))-CorrectionFactor*startMinimize)/180)),parseInt(3000-rMinMaxIcon*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*startMinimize))-CorrectionFactor*startMinimize)/180))];
var PointClose = [parseInt(3000+rMinMaxIcon*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*startClose))-CorrectionFactor*startClose)/180)),parseInt(3000-rMinMaxIcon*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*startClose))-CorrectionFactor*startClose)/180))];
//***Minimize/Close Icon coordinates***
d3.select("#annotation").append("path").attr("d", function() {return highlightPathGenerator((start+end)/2,(start+end)/2,r1,r2);}).attr("stroke-width",5).attr("stroke",function() {return color;}).attr("stroke-opacity",function() {if (opacity*GoldenRatio > 1.0) {return 1.0;} else if (opacity*GoldenRatio == 0) {return 0.5*GoldenRatio;} else {return opacity*GoldenRatio;}}).attr("fill",function() {return color;}).attr("fill-opacity",function() {if (color.match(/rgba/ig)) {return 1.0} else {return opacity;} }).attr("stroke-linejoin","round").attr("id",function () {return "mark"+markCounter;}).attr("class",function(){if (captureClass !== ""){return "markElements"+" "+captureClass;} else {return "markElements";}}).style("opacity",0)
.on("mouseover",function () {
hideOrshowhtmlElements("0");
clearTimeout(highlightGradualFade);
d3.select(this).transition().attr("stroke-width",25).delay(0).duration(250);
d3.select("#annotation").append("text").text(function () {return textDescription;}).attr("class","text2").attr("text-anchor","middle").attr("x",function() {if (coordinates[0]>3000) {return coordinates[0]-500;} else {return coordinates[0]+500;}}).attr("y",function() {if (coordinates[1]>3000) {return coordinates[1]-200;} else {return coordinates[1]+200;}}).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.selectAll(".text2").transition().attr("fill-opacity",0.9).style("opacity",0.9).delay(500).duration(500);
//***Minimize/Close***
if (lastMouseoverMarkElementID !== d3.select(this).attr("id")) {
d3.selectAll(".highlightIcons").remove();
lastMouseoverMarkElementID = d3.select(this).attr("id");
d3.select("#annotation").append("svg:image").attr("xlink:href",minimizeHighlightIcon).attr("title","minimize").attr("alt","minimize").attr("x",function() {return PointMinimize[0]-50;}).attr("y",function() {return PointMinimize[1]-50;}).attr("width","100px").attr("height","100px").style("opacity",0).attr("class","highlightIcons").attr("transform",function () {var x= parseFloat(d3.select(this).attr("x"));var y = parseFloat(d3.select(this).attr("y"));return "rotate("+rotationMinimize+","+(x+50)+","+(y+50)+")";});
d3.select("#annotation").append("svg:image").attr("xlink:href",closeHighlightIcon).attr("title","close").attr("alt","close").attr("x",function() {return PointClose[0]-50;}).attr("y",function() {return PointClose[1]-50;}).attr("width","100px").attr("height","100px").style("opacity",0).attr("class","highlightIcons").attr("transform",function () {var x= parseFloat(d3.select(this).attr("x"));var y = parseFloat(d3.select(this).attr("y"));return "rotate("+rotationClose+","+(x+50)+","+(y+50)+")";});
}
//***I had to add the hideOrshowhtmlElements(1) at the beginning of onclick event below because when you click on the x icon, mouseout event does not fire in firefox. This is not true for Chrome.
d3.selectAll(".highlightIcons").transition().style("opacity",0.9).each("end",function() {d3.select(this).on("mouseover",function(){hideOrshowhtmlElements("0");clearTimeout(highlightGradualFade);d3.selectAll(".highlightIcons").transition().style("opacity",0.9).delay(0).duration(0);d3.select(this).attr("xlink:href",function() {return eval(String(d3.select(this).attr("title"))+"HighlightIconOrange");});}).on("mouseout",function(){hideOrshowhtmlElements("1"); highlightGradualFade = setTimeout(function() {d3.selectAll(".highlightIcons").transition().style("opacity",0).delay(0).duration(0);},2000);d3.select(this).attr("xlink:href",function() {return eval(String(d3.select(this).attr("title"))+"HighlightIcon");});}).on("click",function(){hideOrshowhtmlElements("1"); var type = d3.select(this).attr("title"); highlightIconsOnClick(type);});}).delay(0).duration(0);
//***Minimize/Close***
})
.on("mouseout",function() {
hideOrshowhtmlElements("1");
d3.select(this).transition().attr("stroke-width",5).delay(0).duration(250);
d3.selectAll(".text2").remove();
highlightGradualFade = setTimeout(function() {d3.selectAll(".highlightIcons").transition().style("opacity",0).delay(0).duration(0);},2000);
});
//Fade in/out effect
d3.select("#mark"+markCounter).transition("numberOneFanBrush").attrTween("d",function () {var interpolator = d3.interpolateArray([(start+end)/2,(start+end)/2,r1,r2],[start,end,r1,r2]); return function(t){return highlightPathGenerator(interpolator(t)[0],interpolator(t)[1],interpolator(t)[2],interpolator(t)[3]);}}).delay(0).duration(1500);
d3.select("#mark"+markCounter).transition("fadeInOut").style("opacity",1).delay(0).duration(1500);
function highlightIconsOnClick() {
var highlightSelected = d3.select("#"+lastMouseoverMarkElementID);
if (arguments[0].match(/min/ig)) {
if (highlightSelected.attr("class").split(/\s/).length === 1) {
if (parseFloat(highlightSelected.style("opacity")) > 0) {
highlightSelected.transition("minSingleFadeout").style("opacity",0).delay(0).duration(1500);
} else {
highlightSelected.transition("minSingleFadein").style("opacity",1).delay(0).duration(1500);
}
} else {
var classSelected = d3.selectAll("."+highlightSelected.attr("class").split(/\s/)[1]);
if (parseFloat(highlightSelected.style("opacity")) > 0) {
classSelected.transition("minMultiFadeout").style("opacity",0).delay(0).duration(1500);
} else {
classSelected.transition("minMultiFadein").style("opacity",1).delay(0).duration(1500);
}
}
} else {
if (highlightSelected.attr("class").split(/\s/).length === 1) {
d3.selectAll(".highlightIcons").remove();
highlightSelected.remove();
delete markHash[lastMouseoverMarkElementID];
}
else {
d3.selectAll(".highlightIcons").remove();
var classOfSubject = highlightSelected.attr("class").split(/\s/)[1];
for (var key in markHash) {
if (d3.select("#"+key).attr("class").split(/\s/)[1] === classOfSubject) {
delete markHash[key];
}
}
d3.selectAll("."+classOfSubject).remove();
}
}
}
}
//This is the actual function that inserts a highlight element. Provide an object from the markHash with name,start,end,r1,r2 and color
//***Highlight Path Generator used by above function***
var lineBasis = d3.svg.line().interpolate("basis");
function highlightPathGenerator(start,end,r1,r2) {
//horizontalRoundness parameter is the amount of degrees between the start and end of the horizontal (paralel to the axis of the highlight) b-spline, measure from the center of the figure.
//don't touch too much to this parameter, as seven is a heavenly number. You will be stricken by Tyriel.
var horizontalRoundness;
var horizontalRoundnessParameter = 7;
//***Below if clause is calibrated using tuba1a (451aa) and brca2 (3418aa). The right side of the test condition changes based on the length of the protein. ..*fasta_sorted.length/451 and its powers are the calibration factors. Minimum threshold is 16.***
if ((Math.abs(start-end) > 2*(Math.pow((fasta_sorted.length/451),3/2) + horizontalRoundnessParameter*(fasta_sorted.length/451) + 1)) && (Math.abs(start-end) > 16)) {
horizontalRoundness = parseInt(fasta_sorted.length/355*horizontalRoundnessParameter);
} else {
horizontalRoundness = (end-start)*(GoldenRatio-1)/2;
}
//Similar to above, verticalRoundness is the 'ratio' of the vertical distance between start and end of the vertical b-spline to the height of the highlight.
var verticalRoundness = (GoldenRatio-1)/2;
var Point1 = [parseInt(3000+r1*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180)),parseInt(3000-r1*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180))];
var Point2 = [parseInt(3000+r2*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180)),parseInt(3000-r2*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180))];
var Point3 = [parseInt(3000+r2*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180)),parseInt(3000-r2*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180))];
var Point4 = [parseInt(3000+r1*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180)),parseInt(3000-r1*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180))];
var Point1Inner = [parseInt(3000+r1*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(start+horizontalRoundness)))-CorrectionFactor*(start+horizontalRoundness))/180)),parseInt(3000-r1*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(start+horizontalRoundness)))-CorrectionFactor*(start+horizontalRoundness))/180))];
var Point2Inner = [parseInt(3000+r2*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(start+horizontalRoundness)))-CorrectionFactor*(start+horizontalRoundness))/180)),parseInt(3000-r2*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(start+horizontalRoundness)))-CorrectionFactor*(start+horizontalRoundness))/180))];
var Point3Inner = [parseInt(3000+r2*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(end-horizontalRoundness)))-CorrectionFactor*(end-horizontalRoundness))/180)),parseInt(3000-r2*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(end-horizontalRoundness)))-CorrectionFactor*(end-horizontalRoundness))/180))];
var Point4Inner = [parseInt(3000+r1*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(end-horizontalRoundness)))-CorrectionFactor*(end-horizontalRoundness))/180)),parseInt(3000-r1*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*(end-horizontalRoundness)))-CorrectionFactor*(end-horizontalRoundness))/180))];
var Point1Outer = [parseInt(3000+(r1-(r1-r2)*verticalRoundness)*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180)),parseInt(3000-(r1-(r1-r2)*verticalRoundness)*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180))];
var Point2Outer = [parseInt(3000+(r2+(r1-r2)*verticalRoundness)*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180)),parseInt(3000-(r2+(r1-r2)*verticalRoundness)*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*start))-CorrectionFactor*start)/180))];
var Point3Outer = [parseInt(3000+(r2+(r1-r2)*verticalRoundness)*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180)),parseInt(3000-(r2+(r1-r2)*verticalRoundness)*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180))];
var Point4Outer = [parseInt(3000+(r1-(r1-r2)*verticalRoundness)*Math.cos(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180)),parseInt(3000-(r1-(r1-r2)*verticalRoundness)*Math.sin(Math.PI*(90-(2.5+(HalfTheWidthAngleOfElement+2*HalfTheWidthAngleOfElement*end))-CorrectionFactor*end)/180))];
if (Math.abs(start-end) <= fasta_sorted.length*360/355/2) {
if(highlightTopRound && highlightBottomRound) {
return lineBasis([Point1Inner,Point1,Point1Outer])+"L"+Point2Outer+lineBasis([Point2Outer,Point2,Point2Inner]).replace(/^M/,"L")+"A"+r2+","+r2+" 0 0,1 "+Point3Inner+lineBasis([Point3Inner,Point3,Point3Outer]).replace(/^M/,"L")+"L"+Point4Outer+lineBasis([Point4Outer,Point4,Point4Inner]).replace(/^M/,"L")+"A"+r1+","+r1+" 0 0,0 "+Point1Inner+"Z";
} else if (highlightTopRound) {
return lineBasis([Point1Inner,Point1,Point1Outer])+"L"+Point2+"A"+r2+","+r2+" 0 0,1 "+Point3+"L"+Point4Outer+lineBasis([Point4Outer,Point4,Point4Inner]).replace(/^M/,"L")+"A"+r1+","+r1+" 0 0,0 "+Point1Inner+"Z";
} else if (highlightBottomRound) {
return "M"+Point1+"L"+Point2Outer+lineBasis([Point2Outer,Point2,Point2Inner]).replace(/^M/,"L")+"A"+r2+","+r2+" 0 0,1 "+Point3Inner+lineBasis([Point3Inner,Point3,Point3Outer]).replace(/^M/,"L")+"L"+Point4+"A"+r1+","+r1+" 0 0,0 "+Point1+"Z";
} else {
return "M"+Point1+"L"+Point2+"A"+r2+","+r2+" 0 0,1 "+Point3+"L"+Point4+"A"+r1+","+r1+" 0 0,0 "+Point1+"Z";
}
} else {
if(highlightTopRound && highlightBottomRound) {
return lineBasis([Point1Inner,Point1,Point1Outer])+"L"+Point2Outer+lineBasis([Point2Outer,Point2,Point2Inner]).replace(/^M/,"L")+"A"+r2+","+r2+" 0 1,1 "+Point3Inner+lineBasis([Point3Inner,Point3,Point3Outer]).replace(/^M/,"L")+"L"+Point4Outer+lineBasis([Point4Outer,Point4,Point4Inner]).replace(/^M/,"L")+"A"+r1+","+r1+" 0 1,0 "+Point1Inner+"Z";
} else if (highlightTopRound) {
return lineBasis([Point1Inner,Point1,Point1Outer])+"L"+Point2+"A"+r2+","+r2+" 0 1,1 "+Point3+"L"+Point4Outer+lineBasis([Point4Outer,Point4,Point4Inner]).replace(/^M/,"L")+"A"+r1+","+r1+" 0 1,0 "+Point1Inner+"Z";
} else if (highlightBottomRound) {
return "M"+Point1+"L"+Point2Outer+lineBasis([Point2Outer,Point2,Point2Inner]).replace(/^M/,"L")+"A"+r2+","+r2+" 0 1,1 "+Point3Inner+lineBasis([Point3Inner,Point3,Point3Outer]).replace(/^M/,"L")+"L"+Point4+"A"+r1+","+r1+" 0 1,0 "+Point1+"Z";
} else {
return "M"+Point1+"L"+Point2+"A"+r2+","+r2+" 0 1,1 "+Point3+"L"+Point4+"A"+r1+","+r1+" 0 1,0 "+Point1+"Z";
}
}
}
//***Highlight Path Generator used by above function***
//Global controller, similar to ExtractionPane
var MarkPane = "closed";
//Similar to DropDownExtract
function DropDownMark(selection) {
MarkPane = "open";
selection
.selectAll("rectanglesDropDownMark")
.data([0,1,2,3])
.enter()
.append("rect")
//i*(i-1)* == All will have the same x and width values, but the third will be similar to its correspondent in DropDownExtract
.attr("width",function(d,i) {if (i < 3) {return 1300;} else {return 1300-2*1300/Math.pow(GoldenRatio,2);} })
.attr("height", 100)
//i*(i-1)* == All will have the same x and width values, but the third will be similar to its correspondent in DropDownExtract
.attr("x",function(d,i) {if (i < 3) {return 3000-(1300)/2;} else {return 3000-(1300-2*1300/Math.pow(GoldenRatio,2))/2;}})
.attr("y",function (d,i) {return 2850+i*101;})
//here I add some attr to make the corners rounded
.attr("rx",15)
.attr("ry",15)
//here I add some attr to make the corners rounded
.attr("fill","DimGray")
.attr("fill-opacity",0.9)
.attr("stroke","DimGray")
.attr("stroke-opacity",0.0)
.attr("stroke-width",0.0)
.attr("id",function (d,i) {return "DropDownRectMark"+String(i);})
.attr("class","DropDownRectMark");
//***Input boxes
insertInput('{"left":"641","top":"751","height":"25px","width":"40px","class":"htmlElements","check":"number","flushCounter":"yes"}');
insertInput('{"left":"714","top":"751","height":"25px","width":"40px","class":"htmlElements","check":"number"}');
insertInput('{"left":"787","top":"751","height":"25px","width":"40px","class":"htmlElements","check":"radius"}');
insertInput('{"left":"860","top":"751","height":"25px","width":"40px","class":"htmlElements","check":"radius"}');
insertInput('{"left":"697","top":"772","height":"25px","width":"73px","class":"htmlElements","check":"color"}');
insertInput('{"left":"843","top":"772","height":"25px","width":"73px","class":"htmlElements","check":"none"}');
//***Input boxes
//***Descriptions of Inputs and the Mark Button***
d3.select("#annotation").append("text").text("Start").attr("class","DropDownRectMark").attr("text-anchor","middle").attr("x", 2475).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("End").attr("class","DropDownRectMark").attr("text-anchor","middle").attr("x", 2825).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("outer-R").attr("class","DropDownRectMark").attr("text-anchor","middle").attr("x", 3175).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("inner-R").attr("class","DropDownRectMark").attr("text-anchor","middle").attr("x", 3525).attr("y", 2925).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
//control the roundness of the generated highlights
d3.select("#annotation").append("circle").attr("class","DropDownRectMark higlightRoundnessControls").attr("id","highlightRoundnessTopControl").attr("r",20).attr("cx",3035).attr("cy",3010).style("fill",function () {if (highlightTopRound){return "Orange";}else{return "DimGray";}}).attr("fill-opacity",0.9).style("stroke","Orange").attr("stroke-opacity",0.6).attr("stroke-width",10).on("click",function() {d3.select("#highlightRoundnessTopControl").style("fill",function () {if (highlightTopRound){highlightTopRound = false; return "DimGray";}else{highlightTopRound = true; return "Orange";}});});
d3.select("#annotation").append("circle").attr("class","DropDownRectMark higlightRoundnessControls").attr("id","highlightRoundnessBottomControl").attr("r",20).attr("cx",3377).attr("cy",3010).style("fill",function () {if (highlightBottomRound){return "Orange";}else{return "DimGray";}}).attr("fill-opacity",0.9).style("stroke","Orange").attr("stroke-opacity",0.6).attr("stroke-width",10).on("click",function() {d3.select("#highlightRoundnessBottomControl").style("fill",function () {if (highlightBottomRound){highlightBottomRound = false; return "DimGray";}else{highlightBottomRound = true; return "Orange";}});});
//control the roundness of the generated highlights
d3.select("#annotation").append("text").text("Color:").attr("class","DropDownRectMark").attr("text-anchor","middle").attr("x", 2475).attr("y", 3126).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("Name:").attr("class","DropDownRectMark").attr("text-anchor","middle").attr("x", 3175).attr("y", 3126).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible");
d3.select("#annotation").append("text").text("Mark").attr("class","DropDownRectMark").attr("id","Mark").attr("text-anchor","middle").attr("x", 3000).attr("y", 3227).attr("font-family","Arial").attr("font-size","60px").attr("fill","LightGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).attr("visibility","visible").attr("font-weight","bold")
.on("mouseover", function () {
d3.select(this).transition().attr("font-size",80).attr("fill","Orange").delay(0).duration(250);
})
.on("mouseout", function () {
d3.select(this).transition().attr("font-size",60).attr("fill","LightGray").delay(0).duration(250);
})
.on("click", function () {
if (d3.selectAll(".htmlElementsInputs")[0].some(function(x){
if ((x.value === "")||(x.value === undefined)) {
return true;
}
})) {
alert ("Check your input values!\nStart: Start amino acid number (1-max length),\nEnd: End aminoacid number (1-max length),\nOuter-R: Outer radius of the highlight (0.38-1.07),\nInner-R: Inner radius of the highlight (0.38-1.07),\nColor: Enter a html color name with optional opacity value between 0-1.0 separated by comma such as->Green,0.5. Default opacity is 0.5,\nName: Indicate what you want to be displayed when you move your cursor over the highlight area.");
} else {
var name = document.getElementById("defaulthtmlInput5").value;
var start = document.getElementById("defaulthtmlInput0").value;
var end = document.getElementById("defaulthtmlInput1").value;
var r1 = document.getElementById("defaulthtmlInput2").value;
var r2 = document.getElementById("defaulthtmlInput3").value;
var color = document.getElementById("defaulthtmlInput4").value;
if (parseFloat(start) > parseFloat(end)){
alert ("Start cannot be bigger than end!");
} else if (parseFloat(r1) === parseFloat(r2)) {
alert ("Outer and inner radii cannot be the same!");
} else {
markHash[("mark"+markCounter)] = [name,start,end,r1,r2,color];
residuesToHighlight(markHash[("mark"+markCounter)]);
markCounter++;
}
}
});
//***Descriptions of Inputs and the Mark Button***
}
//Similar to DropDownExtract
//Calculate domain percentage
function calculateDomainPercentage () {
var count = 0;
for (var i = 0; i < ids["con"].length;i++) {
if(!(d3.select(ids["con"][i]).attr("class") === null) && !(d3.select(ids["con"][i]).attr("class") === "allCons")) {
count++;
}
}
var percentage = parseFloat(count/fasta_sorted.length*100).toFixed(1);
//alert (percentage+"percent of your protein is made up of domains!");
return percentage;
}
//Calculate domain percentage
//***Mark Tab***
var DropDownClickMark = 0;
d3.select("#annotation").append("text").text(function() {return "domain percentage: "+ calculateDomainPercentage();}).attr("class","Options").attr("id","OverviewMark").attr("text-anchor","middle").attr("x", 3000).attr("y", 2800).attr("font-family","Arial").attr("font-size","60px").attr("fill","DimGray").attr("stroke","DimGray").attr("fill-opacity",0.9).attr("stroke-opacity",0.0).style("visibility","hidden").style("opacity",0)
.on("mouseover",function() {
d3.select("#OverviewMark").transition().attr("font-size","120px").attr("fill","Orange").delay(0).duration(500);
d3.selectAll(".overviews").style("opacity",0);
})
.on("mouseout",function() {
d3.select("#OverviewMark").transition().attr("font-size","60px").attr("fill","DimGray").delay(0).duration(500);
d3.selectAll(".overviews").style("opacity",1);
})
.on("click",function() {
if (DropDownClickMark == 0) {
//Close other open overview tabs
if (ExtractionPane === "open") {
d3.selectAll(".DropDownRectExtract").remove();
DropDownClickExtract = 0;
ExtractionPane = "closed";
}
//Close other open overview tabs
d3.select("#annotation").call(DropDownMark);
} else {
d3.selectAll(".htmlElements").remove();
d3.selectAll(".DropDownRectMark").remove();
MarkPane = "closed";
}
if (DropDownClickMark == 0) {
DropDownClickMark = 1;
} else {
DropDownClickMark = 0;
}
});
//***Mark Tab***
//***Overview Tabs***
d3.select("#annotation").selectAll("overviewRects").data(overviewTabArray).enter()
.append("path")
.attr("d",function(d,i) {return "M"+(2320+(i+1)*1300/(overviewTabArray.length+1))+",2690L"+(2320+(i+1)*1300/(overviewTabArray.length+1)+45)+",2690A15,15 0 1,1 "+(2320+(i+1)*1300/(overviewTabArray.length+1)+45)+",2720L"+(2320+(i+1)*1300/(overviewTabArray.length+1))+",2720A15,15 0 1,1 "+(2320+(i+1)*1300/(overviewTabArray.length+1))+",2690Z"})
.attr("fill",function(d,i) {if (i == 0) {return "Orange";} else {return "DimGray";}})
.attr("fill-opacity",0.6)
.attr("stroke",function(d,i) {if (i == 0) {return "Orange";} else {return "DimGray";}})
.attr("stroke-opacity",1.0)
.attr("stroke-width",6)
.attr("stroke-linejoin","round")
.attr("class","overviews")
.attr("id",function (d,i) {return d.id+"Button";})
.on("click",function (d,i) {
var ID = d3.select(this).attr("id");
d3.selectAll(".overviews").filter(function() {if (d3.select(this).attr("id") == ID) {return 0;} else {return 1}}).each(function () {d3.select(this).style("fill","DimGray").style("stroke","DimGray");});
d3.select(this).style("fill","Orange").style("stroke","Orange");
for (var i =0;i<overviewTabArray.length;i++) {
if (overviewTabArray[i].id == (ID.replace("Button",""))) {
d3.select("#"+overviewTabArray[i].id).style("visibility","visible").style("opacity",1);
} else {
d3.select("#"+overviewTabArray[i].id).style("visibility","hidden").style("opacity",0);
}
}
});
//***Overview Tabs***
//***Input Focus and Blur***
function inputFocus() {
var ID = arguments[0];
ID = "#"+ID;
if (NeonizeMe == 1) {
if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)) {
d3.select(ID).style("border-width","4px").style("border-color","rgba(30,144,255,0.6)")
.style("box-shadow","0px 0px 10px DodgerBlue,0px 0px 16px DodgerBlue,0px 0px 26px DodgerBlue,0px 0px 42px DodgerBlue,0px 0px 68px DodgerBlue,0px 0px 110px DodgerBlue");
} else {
d3.select(ID).style("border-width","4px").style("border-color","rgba(255,165,0,0.6)")
.style("box-shadow","0px 0px 10px Orange,0px 0px 16px Orange,0px 0px 26px Orange,0px 0px 42px Orange,0px 0px 68px Orange,0px 0px 110px Orange");
}
} else {
if (d3.select("body").style("background-color").match(/rgb\s*\(\s*0\s*,\s*0\s*,\s*0\s*\)/i)) {
d3.select(ID).style("border-width","4px").style("border-color","rgba(30,144,255,0.6)");
} else {
d3.select(ID).style("border-width","4px").style("border-color","rgba(255,165,0,0.6)");
}
}
}
function inputBlur () {
var ID = arguments[0];
ID = "#"+ID;
d3.select(ID).style("border-width","2px").style("border-color","rgba(105,105,105,0.6)").style("box-shadow","none");
}
//***Input Focus and Blur***
<!--A new Tab #2: Mark Tab -->
<!--File API -->
insertInput('{"left":"1383","top":"1362","height":"25px","width":"25px","class":"htmlFileUploadElements","check":"none","prefix":"fileUpload"}');
fileUploadIcon = "data:image/png;base64,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";
//File Input
d3.select("#fileUploadhtmlDiv0").style("visibility","hidden");
d3.select("#fileUploadhtmlForm0").style("visibility","hidden");
d3.select("#fileUploadhtmlInput0").attr("type","file").attr("onchange","readFunc(event)").attr("accept","text/plain").attr("name","fileUploadArea").style("visibility","hidden");
//File Input
//Action Tab Lower Right Corner
d3.select("#annotation").append("text").text("Action:").attr("x",5800).attr("y",5975).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","start").style("fill","DimGray").attr("fill-opacity",0.9).attr("id","fileUploadActionOpts").attr("class","Options");
var actionHash = [{"action":"Mark","control":"MarkPane,fileLoadedStatus","function":pacedMarkPlacerFunc},{"action":"Hist","control":"HistogramPane,fileLoadedStatus","function":registerNewHistogram}];
d3.select("#annotation")
.selectAll("actionOptions")
.data(actionHash)
.enter()
.append("text")
.text(function(d,i){return d.action})
.attr("x",function(d,i) {return 6000+200*i;})
.attr("y",5975)
.attr("font-family","sans-serif")
.attr("font-size", 45)
.attr("text-anchor","start")
.style("fill","DimGray")
.style("opacity",0.2)
.attr("fill-opacity",0.9)
.attr("stroke-opacity",0)
.attr("id",function (d,i) {return "actionOption"+i;})
.attr("class","actionOptions")
.on("click",function (d,i) {
var controlElements = d.control.split(/,/);
if (controlElements.every(actionHashControlFunc)) {
d.function();
} else {
alert("Either the required pane is not open or the file is not loaded. Check if these conditions are met..");
}
});
//Action Tab Lower Right Corner
d3.select("#annotation").append("svg:image").attr("xlink:href",fileUploadIcon).attr("title","fileUploadIcon").attr("alt","fileUploadIcon").attr("x",5900).attr("y",5800).attr("width","100px").attr("height","100px").style("opacity",0.62).attr("id","fileUploadIcon");
d3.select("#fileUploadIcon")
.on("mouseover", function () {
d3.select(this).style("opacity",1);
})
.on("mouseout", function () {
d3.select(this).style("opacity",0.62);
})
.on("click", function () {
if (navigator.userAgent.match(/iphone|ipad|ipod/i)) {
alert("Unfortunately your device does not have file browsing system. You won't be able to use this option..");
}
else if (window.FileReader) {
document.getElementById("fileUploadhtmlInput0").click();
} else {
alert("Unfortunately your browser does not support FileReader, consider upgrading or switching to another browser..");
}
});
d3.select("#annotation").append("text").text("No files loaded").attr("x",6050).attr("y",5875).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","start").style("fill","DimGray").attr("fill-opacity",0.9).attr("id","fileUploadStatus").attr("class","Options");
var fileOutput;
var pace;
var fileLoadedStatus = 0;
function readFunc(event) {
var inputID = event.target.id;
var fileReader = new FileReader();
fileReader.onload = function () {
if (event.target.files[0].name.length > 15) {
document.getElementById("fileUploadStatus").textContent = event.target.files[0].name.substring(0,11)+"...";
} else {
document.getElementById("fileUploadStatus").textContent = event.target.files[0].name;
}
fileOutput = fileReader.result;
fileOutput = fileOutput.split(/\n/);
for (var i = fileOutput.length-1;i>=0;i--) {
if (fileOutput[i].match(/^\s*\t*\n*\r*$/)) {
fileOutput.pop()
} else {
break;
}
}
if (fileOutput[0].match(/pace/)) {
var firstLine = fileOutput.shift();
pace = parseInt(firstLine.replace(/^\s*\t*pace\s*\t*=\s*\t*/,""));
captureClass = firstLine.replace(/^\s*\t*pace\s*\t*=\s*\t*[0-9]+/,"").replace(/.*;?\t*\s*bind\s*\t*=\s*\t*/,"").trim();
}
fileLoadedStatus = 1;
d3.selectAll(".actionOptions").style("fill","Orange").style("opacity",0.9);
}
fileReader.readAsText(event.target.files[0]);
}
function pacedMarkPlacerFunc() {
if (pace === undefined || pace === null || typeof pace !== "number" || isNaN(pace)) {
alert ("You should explicity set 'pace' value in your file..\nSomething like: pace = 300")
} else {
d3.select("#fileUploadIcon").style("opacity",0).style("visibility","hidden");
d3.selectAll(".actionOptions").style("visibility","hidden");
d3.select(document.body).append("div").attr("style","width:280px;position:absolute;background:transparent;height:123px;left:610px;top:682px").attr("id","blockUserInteractionDiv");
var i = 0;
var pacedMarkPlacer = setInterval(function () {
var fields = fileOutput[i].split(/\t/);
var checkStatus = 0;
document.getElementById("defaulthtmlInput5").value = fields[5];
//nothing to check here
document.getElementById("defaulthtmlInput0").value = fields[0];
checkStatus += inputCheckNumber("defaulthtmlInput0","number");
document.getElementById("defaulthtmlInput1").value = fields[1];
checkStatus += inputCheckNumber("defaulthtmlInput1","number");
document.getElementById("defaulthtmlInput2").value = fields[2];
checkStatus += inputCheckNumber("defaulthtmlInput2","radius");
document.getElementById("defaulthtmlInput3").value = fields[3];
checkStatus += inputCheckNumber("defaulthtmlInput3","radius");
document.getElementById("defaulthtmlInput4").value = fields[4];
checkStatus += inputCheckColor("defaulthtmlInput4");
if(fields[6] !== undefined && fields[6].match(/round/i)) {
if (!highlightTopRound) {
d3.select("#highlightRoundnessTopControl").on("click")();
}
} else {
if (highlightTopRound) {
d3.select("#highlightRoundnessTopControl").on("click")();
}
}
if(fields[7] !== undefined && fields[7].match(/round/i)) {
if (!highlightBottomRound) {
d3.select("#highlightRoundnessBottomControl").on("click")();
}
} else {
if (highlightBottomRound) {
d3.select("#highlightRoundnessBottomControl").on("click")();
}
}
if (checkStatus === 5) {
d3.select("#Mark").on("click")();
}
i++;
if (i == fileOutput.length) {
clearInterval(pacedMarkPlacer);
pace = null;
captureClass = "";
fileOutput = null;
fileLoadedStatus = 0;
d3.select("#blockUserInteractionDiv").remove();
document.getElementById("fileUploadhtmlInput0").value = null;
document.getElementById("fileUploadStatus").textContent = "No files loaded";
d3.select("#fileUploadIcon").style("opacity",0.62).style("visibility","visible");
d3.selectAll(".actionOptions").style("fill","DimGray").style("opacity",0.2).style("visibility","visible");
}
},pace);
}
}
function actionHashControlFunc(value,index) {
if (value.match(/pane/i)) {
if (eval(value) === "open") {
return true;
} else {
return false;
}
} else if (typeof eval(value) === "number") {
if (eval(value) === 1) {
return true;
} else {
return false;
}
} else {
alert("Control function fails to check for conditions to trigger action..");
return false;
}
}
<!--File API -->
<!--Histogram-->
//HistogramPane is always open
var HistogramPane = "open";
var histogramMinAbsoluteHeight;
var histogramMaxAbsoluteHeight;
var histogramStepDistance;
var conservationScores = ids["con"].map(function(d,i){return parseInt(d.replace(/^.*Conservation-Score_/,""));});
var Or_Hist_Path_Data = {};
for (var i = 0;i< ids["con"].length;i++) {
var pathData = d3.select(ids["con"][i]).attr("d");
Or_Hist_Path_Data[ids["con"][i]] = pathData;
}
calculateHistogramStepDistance();
function calculateHistogramStepDistance() {
histogramMinAbsoluteHeight = d3.min(conservationScores);
histogramMaxAbsoluteHeight = d3.max(conservationScores);
var firstTopRightCornerX = extractHistCorners(ids["con"][0]).tRx;
var firstTopRightCornerY = extractHistCorners(ids["con"][0]).tRy;
var firstBottomRightCornerX = extractHistCorners(ids["con"][0]).bRx;
var firstBottomRightCornerY = extractHistCorners(ids["con"][0]).bRy;
if (histogramMinAbsoluteHeight === histogramMaxAbsoluteHeight) {
histogramStepDistance = Math.sqrt(Math.pow((firstTopRightCornerX- firstBottomRightCornerX),2)+Math.pow((firstTopRightCornerY-firstBottomRightCornerY),2));
} else {
histogramStepDistance = Math.sqrt(Math.pow((firstTopRightCornerX- firstBottomRightCornerX),2)+Math.pow((firstTopRightCornerY-firstBottomRightCornerY),2))/Math.round(1+(conservationScores[0]-histogramMinAbsoluteHeight)/(histogramMaxAbsoluteHeight-histogramMinAbsoluteHeight)*9);
}
}
function changeBarHeight(id,stepSize){
if (stepSize > 10) {
alert ("Maximum step size is 10!");
stepSize = 10;
}
var angleLeft = Math.atan(Math.abs((extractHistCorners(id).tLy-extractHistCorners(id).bLy)/(extractHistCorners(id).tLx-extractHistCorners(id).bLx)));
var angleRight = Math.atan(Math.abs((extractHistCorners(id).tRy-extractHistCorners(id).bRy)/(extractHistCorners(id).tRx-extractHistCorners(id).bRx)));
var neWtLx = extractHistCorners(id).bLx+(stepSize*histogramStepDistance*Math.cos(angleLeft))*Math.sign(extractHistCorners(id).tLx-extractHistCorners(id).bLx);
var neWtLy = extractHistCorners(id).bLy+(stepSize*histogramStepDistance*Math.sin(angleLeft))*Math.sign(extractHistCorners(id).tLy-extractHistCorners(id).bLy);
var neWtRx = extractHistCorners(id).bRx+(stepSize*histogramStepDistance*Math.cos(angleRight))*Math.sign(extractHistCorners(id).tRx-extractHistCorners(id).bRx);
var neWtRy = extractHistCorners(id).bRy+(stepSize*histogramStepDistance*Math.sin(angleRight))*Math.sign(extractHistCorners(id).tRy-extractHistCorners(id).bRy);
var neWpath = histPathRecompile (id,neWtLx,neWtLy,neWtRx,neWtRy);
d3.select(id).transition("histUpdate").attr("d",neWpath).delay(0).duration(1000);
}
function extractHistCorners(id) {
var hash = {};
hash.bLx = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[1]);
hash.bLy = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[2]);
hash.tLx = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[20]);
hash.tLy = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[21]);
hash.tRx = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[12]);
hash.tRy = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[13]);
hash.bRx = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[9]);
hash.bRy = parseFloat(Or_Hist_Path_Data[id].split(/[MLAZ,]|\s+/)[10]);
return hash;
}
function histPathRecompile (id,tLx,tLy,tRx,tRy) {
return "M"+extractHistCorners(id).bLx+","+extractHistCorners(id).bLy+" A2250.000,2250.000 40.000 0,1 "+extractHistCorners(id).bRx+","+extractHistCorners(id).bRy+" L"+tRx+","+tRy+" A2430.000,2430.000 0.000 0,0 "+tLx+","+tLy+" Z";
}
function histogramUpdate (array) {
var arraySign = array.map(function(x){if(Math.sign(parseFloat(x))===0){return 1;}else{return Math.sign(parseFloat(x));}});
array = array.map(function(x){return Math.abs(parseFloat(x));});
var min = d3.min(array);
var max = d3.max(array);
if (array.length === ids["con"].length) {
for (var i = 0;i<ids["con"].length;i++) {
var stepSize = Math.round(arraySign[i]*(1+(array[i]-min)/(max-min)*9));
changeBarHeight(ids["con"][i],stepSize);
}
} else {
alert("Input file has different number of entries compared to conservation track..");
}
}
var registeredHistograms = [];
var registeredHistogramID = -1;
var activeHistogram = [];
var histogramGradualFade;
function registerNewHistogram () {
var array = fileOutput;
if (registeredHistogramID === 2) {
registeredHistogramID = 0;
} else {
registeredHistogramID++;
}
if (registeredHistograms.length === 3) {
registeredHistograms.pop();
registeredHistograms.unshift([array,registeredHistogramID]);
} else {
registeredHistograms.unshift([array,registeredHistogramID]);
}
render();
function render() {
d3.selectAll(".registeredHistogramCircles").remove();
if (registeredHistograms.length === 0) {
activeHistogram = [];
histogramUpdate(conservationScores);
} else {
d3.select("#annotation").selectAll("registeredHistograms").data(registeredHistograms).enter().append("circle").attr("cx",3000).attr("cy",function(d,i){return 550+i*70}).attr("r",20).attr("fill-opacity",0).attr("fill","DimGray").attr("stroke-width",15).attr("stroke",function(d,i){return ["#1b9e77","#d95f02","#7570b3"][d[1]];}).attr("stroke-opacity",0.9).attr("class","registeredHistogramCircles").attr("id",function(d,i){return "registeredHistogramCircles"+i;}).style("opacity",0)
.on("mouseover",function(d,i){
d3.selectAll(".registeredHistogramCircles").transition().style("opacity",1).delay(0).duration(500);
var cx = parseFloat(d3.select(this).attr("cx"));
var cy = parseFloat(d3.select(this).attr("cy"));
var ID = d[1];
clearTimeout(histogramGradualFade);
d3.selectAll(".histogramIcons").remove();
d3.select("#annotation").append("svg:image").attr("xlink:href",closeHighlightIcon).attr("title","close").attr("alt","close").attr("x",function() {return cx+30;}).attr("y",function() {return cy-60;}).attr("width","50px").attr("height","50px").style("opacity",0).attr("class","histogramIcons");
d3.selectAll(".histogramIcons").transition().style("opacity",0.9).each("end",function() {d3.select(this).on("mouseover",function(){clearTimeout(histogramGradualFade);d3.select(this).attr("xlink:href",function() {return eval(String(d3.select(this).attr("title"))+"HighlightIconOrange");});}).on("mouseout",function(){histogramGradualFade = setTimeout(function() {d3.selectAll(".histogramIcons").remove();d3.selectAll(".registeredHistogramCircles").transition().style("opacity",0).delay(0).duration(0);},2000);d3.select(this).attr("xlink:href",function() {return eval(String(d3.select(this).attr("title"))+"HighlightIcon");});}).on("click",function(){clearTimeout(histogramGradualFade); d3.selectAll(".histogramIcons").remove(); var array = []; for (var i = 0;i<registeredHistograms.length;i++){if(registeredHistograms[i][1] !== ID){array.push(registeredHistograms[i]);}}; registeredHistograms = array; render();});}).delay(0).duration(0);
})
.on("mouseout",function(d,i){
histogramGradualFade = setTimeout(function() {d3.selectAll(".histogramIcons").remove();d3.selectAll(".registeredHistogramCircles").transition().style("opacity",0).delay(0).duration(0);},2000);
})
.on("click",function(d,i){
//alert ("My data:"+d[0]+","+"My index:"+d[1]);
d3.selectAll(".registeredHistogramCircles").transition().each("end",function(){if(d3.select(this).attr("id") === "registeredHistogramCircles"+i){d3.select(this).transition().attr("fill-opacity",0.9).delay(0).duration(500);}}).attr("fill-opacity",0).delay(0).duration(0);
activeHistogram = [d];
histogramUpdate(d[0]);
});
}
pace = null;
captureClass = "";
fileOutput = null;
fileLoadedStatus = 0;
document.getElementById("fileUploadhtmlInput0").value = null;
document.getElementById("fileUploadStatus").textContent = "No files loaded";
d3.selectAll(".actionOptions").style("fill","DimGray").style("opacity",0.2).style("visibility","visible");
}
}
function showNewHistogramValue(id) {
if (activeHistogram.length !== 0) {
var index = ids["con"].indexOf(id);
var XY = computeHypotheticalBarDistance(id);
d3.select("#annotation").append("text").text(function () {return activeHistogram[0][0][index];}).attr("class","text2").attr("text-anchor","middle").attr("x",XY[0]).attr("y",XY[1]).attr("font-family","sans-serif").attr("font-size","100px").attr("fill","DodgerBlue").attr("stroke","DodgerBlue").attr("fill-opacity",0.0).attr("stroke-opacity",0.0).attr("visibility","visible");
}
function computeHypotheticalBarDistance(id) {
var stepSize = 20;
var angleLeft = Math.atan(Math.abs((extractHistCorners(id).tLy-extractHistCorners(id).bLy)/(extractHistCorners(id).tLx-extractHistCorners(id).bLx)));
var angleRight = Math.atan(Math.abs((extractHistCorners(id).tRy-extractHistCorners(id).bRy)/(extractHistCorners(id).tRx-extractHistCorners(id).bRx)));
var neWtLy = extractHistCorners(id).bLy+(stepSize*histogramStepDistance*Math.sin(angleLeft))*Math.sign(extractHistCorners(id).tLy-extractHistCorners(id).bLy);
var neWtRx = extractHistCorners(id).bRx+(stepSize*histogramStepDistance*Math.cos(angleRight))*Math.sign(extractHistCorners(id).tRx-extractHistCorners(id).bRx);
var newX = (extractHistCorners(id).bLx+neWtRx)/2;
var newY = (neWtLy+extractHistCorners(id).bRy)/2;
return [newX,newY];
}
}
<!--Histogram-->
<!--WindowInterface-->
var sampleLoc = {"x":1500,"y":1500,"width":1500,"height":2000,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":2000,"maxWidth":5000,"maxHeight":5000};
//global window icons base64
var closeWindowIcon = "data:image/png;base64,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";
var enlargeWindowIcon = "data:image/png;base64,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";
var relocateWindowIcon = "data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAH4AAACbCAYAAACkqi+5AAAABHNCSVQICAgIfAhkiAAAAAlwSFlzAAAAJwAAACcBKgmRTwAAABl0RVh0U29mdHdhcmUAd3d3Lmlua3NjYXBlLm9yZ5vuPBoAAA/WSURBVHic7Z17mFT1ecc/72+GYRfCZRVURKrxgsCIt0qfaA3GJ6aEGNPi48pTqS2h7KyKJK1aL20a17Rpmj55nmggXkBtDDEWR3NTY6xpEoPXiqTArlwUxUs2iLoiIOzszpy3f8wu7C5zn3N+5+zM+TwPfyxzzu99Z77ze+c9v8v7E+oMbcNs7WBS2uEIR5ioMFGECSijRGgQaFRlFIDCfiOoI6SNshvlA0f5AMMHBn4PvBlPstfnt1QR4rcDXtPRTEwMUx3l40Y53lGOBWKuGTB0KWxXZVNsDO3T7mWPa217SE0Kv3kRY3p3M9PATDVMw2GEFcOCKrxpIqwjwwtBjgY1I7y2YTo2MZMMf4owHfX3vSlkMKzPCE+fvpqtfvqSi2EvvIK0z+dCo5ytDuP89icXIrzWa3g0SF+AYS88QPsl3ABMKfc+NTg4dBlDF0q3wP600g1gDFFRRAyj1GEscJgjjBUHU6mfYtiaTvOj037E25W24RY1IXzHJcxVuLDgRUJKDNvF4TUMb3Q7vPMqdF2aJFOqnbY2THMHR6Qdjo0apqhyPMKUcn5W1OAY5Zf7m3j8rBX0lnqf29SE8Fuamdyr3JTjpR0ZYUOslw2rT+fNtjYct22/soCx+3uIR2AmSlwhUsp9jrBTYdVpSV5326dSqAnhAdqbuQXlcIUPifBcg8MLJyV5t5R7n/4CY5pG0pRxGCUxYqaHSAb2jzTsMTH2nHQ/u0tp55UFjE2n+IRjOEcdJhS7XiFjhGQ8ydOltO8mNSP8y/P5hDHsO/lk2iVPz9Y2zMsdTEOJAzOAExEmKXysUNsCex3oFHhdlHaEjg7Yku9noq0NM28js6IR5pbyBRB4bud7rD7/N6RLea9uUDPC50MTjOjYxbniMFuFc8CdzF9hj8CzjrBmr/LMOUn2D73mwWYicTgb+EL/aGBeDJtEWRlP0uOGf8WoWeG3NDM5rVyswoXAeC9tCex1lF8Y4SfxJK8OfX3zIsakdzMP+JNC7TiGbe/v5I7zf5N9svCSmhV+4yVcLML1Pph+UeCOeJKXh76wfj5nRhwWoIzMe7dhW/d4lnud8Vf8TBp03vqIx4BdPpie5Qj3tF/Cv3c0c9TAF05bzTqN8h/Ajrx3O5zQ0MXfqMedsmZ7PED7fBbjsDjXawKOo7yFYRuwwzj8QQ3d4rAPwECjA40IRzrC0QLHiXKcltdZ9ivcuwl+ODARfLaZxjGQEOWkfDca5eczHubnZdgqi5oWfsOFNEVG8RPlQGjdocoaJ8IzXQ7t55c5ibL+ckZHu4kLnO0osxEml3SjsFGUf44nD/b0jmZiQEKVaXnuUQx3n7Ka9eX4WCo1LTxARzPXKIwT+HE8yf+53PYMhL9Q5TNAY6FrFfYYuGXgM/vaBCMaumgh+2iZi727evj6uT9zf6q35oW3wSsLGNvdy2WiNAOj810n4KB8O/4QyQP3zmVkzxiuUSd39HBg46kPcZfbPofCu8i2ZsbtE5YAF0mB8XtR7p/xEMsFFGDTPA53olynyphc1zvK8lMfZrObvobCe8CmZmZm4KsUmDEU+EE8yfID98xnasZh6aAJHyEl8OMZSZ7p/5K4RSj8EDTBJISLUP4YmAQcAaSAt4G3cXgCwxop8pzdeRGjuhq4AZiT1xasnJnknv6/Oy6hWeE8yM7hx2BVqfMN5RIK34e2MBfhK2SHWIt9LrtQVqF8Xe7mnUIXbpjPAlGuzhf6I8LN0x/kCejL9IXrHOXFh+P8jxezif3UvfB6JSeT4S76elqZ7EX4Jl18QwrM62+4lAuM0gZEh74mkIpAYlqSLZCdSMo3yeQmNTtyVwqa4M/I8DyViQ7wMZR/oYlHdWH++YBTH+SXEuFm4VBBHSHWK8zq/9uG6FDHPV5b+UuUVZS4cKIE2unhk/K9/MPE7ZdyEco/DfivXcbQNmM1z7vkQ8nUZY/XBGei3I17ogOcwgge1Ob8bZ7yII8YeABAYN2IKH/lh+jg7hsfFuhCxhNhDXC4640LJ9CI3PISv853yXlx1h4JnTPifGfCcj5y3YcSqbtQrwm+AdzooYluokyV23nLQxtVU1ehXhNMApZ6bKaBNF/12EbV1JXwwOUUGEt3045eVXgdn9/Um/AXWbIzkgyftmSrIupGeE0wjuyonCWDzLVmqwLqRniE47D5FKMcb81WBdSP8M7g9W+eI0yyaq9M6kd4Yaxli4HcudtP/Qiv7LRsseCsnd/Uj/DwB8v2Oi3bK4v6Eb6BN8BifRqhw5qtCqgb4WUZKeC/rRnM8DNrtiqgboQHQPmpJUs7OIb/tWSrIupL+F2sBl6zYOlbthZUVEpdCS/ZLchf89jM7xnN7R7bqJq6Eh6AD/gBwq88at1BuUq+fehe+aBRd8JLkgxpmuHQfewu0CYrg53U9VN3wgPIPXQh/Dm4ulhiBSv4Vxfb85S6FB5A7uJl4EzgqSqbyiDcKCtodXu3i5fUrfAAsoL3GMkc4Hqgq4ImnsJwjtzFN112zXPqbs1dPnQh44mxBLgYOIP8n81u4AmEe+UufmHNQZcJhc+BXsUUejkDOAbDkcA+smP92+niebFUmSokJCQkJCTEP3QpY7WFm7TZxeNOLFDXj3OukCKG8G800aGtfM5vd0olFL5anAMrd09EeUxbeUQX83FffSqBUPhqiQ4pdqB8HkOHJmjThTT45FVRQuGrxcm5Vr8RuJkYW7WVv7btUimEwldLbuH7mYJynyZ4Uhcz3ZpPJRAKXy1a0u6cCzCs1wS3BWUzZSh8tcRK3pY1AvgSaTYHIfyHwldL4VCfi8l94f9X2kLcE59KIBS+WjKHljArkfMRfqcJbtNFuUuZekkofLVEq9qBmw3/0Wz49/pwgoGEwldLacldMY5GuY8Ev9YEM11oryih8NXijvD9nAes0wS39RVy8IxQ+GpxV3jIlj39Engb/kPhq8VUnNwV46i+8P+CXlH42LJKKNlp/RRRZtJEikaUBjIIMVIYutnHLvme92elBRL3e/xQZuHwnCa4H7hGVvCeG40WDCMKwiImEeMYlAkUOkJb+RBDJ1t5Qywelek32sIFCE9aMteF8jUms6zavXl5hdcvMpEY03HKLCFiSJHhVVayXWT4rDOvFG1hDmJ5ta3wEhmulrsrr4ObU3htYSowtWLHsi2/C6wrdpLDcEdb+RzKYz6YdoD76eVa+c/yT7EYFLpVEW3lLKoVHUCZCJyriSKH6Q5//CoEbYDLGcEWbeHLhapm57v5IK2c4mpZMGU0yixt8yzz9R/H9/fWhHArTbyoLZxT6k0HhNclHItyrAeOjeEdTvOg3WBgAlP6/QyEpzXB93UxRxa72ABoMzHSHi4USDNJr+AIz9r3l6AID9mc7XIMm7WFLxeKtNkefxgneh6yMky3OQlhDe+f4ythPMKtdLJWF/PJXBcY/RRRHE9C/FDGsJQJFuzYJZjC93Maht9qK4/oVYMPPzRMZSK2wlXKcj1ZOwRZ+CzK50mzSRO09W/8MIjF314tnnQMO8T3rL5URgM308RGbWFOlAxjLf7yNmgbUWmroSFdwZQwPvkUOmSUTfgIOWS79QeD/lJSZLdoD7xvD86Az0/I4LB7SDv7GEFq0P/0sIvYQU+jCCOLuu0mO2kA9lq16SUO0aIdx3C13Em7FX9KxGAsb/bba/mL5jXFn+PXBk10AINaDrvjamzsvnhWv8qKH2ViEMvz6DtqbN5eCyZ3aRxWW/OlDAxDkwdvraVJ1liPLxzqHy92zLhfGKsnNyg7h1MtuJIoHOoDGeYBDCMtfiNNML/9VZJP+A8ZzaNWPSkDI8tIYdjhvSVSbK4r4VcHuZhxdpImwma8XiYlvFKTa/Hyh/rAhnnoE15uZy+GNzy0s4ejeNPD9v0jd3K3nRU8Y92XMji4AucOOqisnmsxeulmbdBPbKiY3I9z9wU9iT0gvAhKAy+hLj7eGRzSrJNVfORam0EjV6hXfuiDJ2UxaM2dLCPFhzxN1JVF+9008mwlK0CHFYeG+mdlJVt98aUMDtkgIUl6uJ0XEF4FMhW2uoMG1sit7KrWwcAztMdLsJO6fnION/ZthNisC9lOjJMQJhddmiUohndpYGtdCH6QgcL3ECXpmydlUFDMvv1wG1Vpp5XDcZiI0kCUBhyEKCnSdBNhFw475c4aG44tjYHCPyLf5X3fPCmDklaP9EWA9/r+hQzm4Gc4TMI8hNuk3aC/x79PF4/76kkZhMJXT7/wDwynkytC4aulP6s3wyfMQyh89WSf47fKncE+RHgoofDVkh2yvc9vN8rFmvD6RaZoczDquLqMweEBv50oF3s9PsJJHMY/aiuzta2GIo2wRu7mdb/dKBebwgtKI8o8OrlWF3G8Ndte0st/+e1CJVjbQ6OL+Qxm0JktCqxnFD+tsyHeQGCvx8shtgQ4nX3cpK18ttxSHiHVYU94kze6xFDmMJ7r9UpOtuZPnWMzySpsSziCDFdogsV6JU2WfKpb7AlfqDjiYOJkuFFb+WxNF03ymeD0+MFkw38n1wftEJ9awc/krhQmYkhogsX6txzmuk91TBCSu1KIEwnDv5vYEz5Tta0RfeH/Bm1lhis+1TFBD/W5mIDSogkW6xIOd6nNusNe2DSIy1sq4vQyVVv4LQ08KcuG1HwJKYi9Hp/2ZGRuBMKnSXGjtjDLg/ZrluGS3BVjPMJlmuDKUuq4hgzP3/hCTMXwD3oF83RpjRVZcpmgDuBUQwSH2aS4KQz/+bEnvFovYDyuL/wv0atqspRqVdgU3q9p1xNJc51ewTxdSINPPgSOWknuipEN/yOz4b8my6eXSRBn57xDGYtwGQmW6CKO9tsdP6m1rL5UTiDCtfUc/ms5uSuMYHCYTYyvaCuzNWj+eYzN3/gg9fiBjEaZR4K/1wR/5LcztrDZ44MqfBZhCvB32sICvZzRfrvjNbU4gFMNgnAWjTW48WMI9mbnFCnhV7QTIYPiwJDZNocezJACiTqkcqQhjTNkq7KSIjJgXlBxclTs7h106gNAhP10Mgb4sKjXwxB7whfP6rtYwbeCXh+uVghOqBdeDEW3R3CE7+ElS36EEJwBnNdrvhBiwAjGkG2Utdb8CAHs9vh8OX2GPay35kcIEIQBHEN7TRc5DihBSO7CMO8Dfid3H/E+m6z5EHIAf3u8sE6SFVbIDqkKf5M7DcO8X/iZ3L0rK2r0nJphgH+hXodXJchaw68VOEqK31mzHXIINlfgDFxevU2+PzwK+tcq/vR4w4vW7IbkxI/f+F662WDRbkgOrAjft4FB+v7Y2HfWTYiP2OnxbQPCvIRhPgjYCvX9dvZwdPAP46sH7Ajf0WfH4aWaPWN2mGFH+KP6Qn1DGOaDgh3hd2AQdshyOq3YCymKHeEbMOEQbbCw+Ry/zqKtkCL8P6SypVbyNVdSAAAAAElFTkSuQmCC";
var dragWindowIcon = "data:image/png;base64,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";
var magnifyWindowIcon ="data:image/png;base64,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";
var minifyWindowIcon ="data:image/png;base64,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";
//global window icons base64
var relocateWindow = "";
function renderWindow(type,ID,location,funcToCall,arg) {
var internalCoordinates;
var dragTransparency = d3.behavior.drag().origin(function(){var x = parseFloat(d3.select(this).attr("x"));var y = parseFloat(d3.select(this).attr("y"));return {"x":x,"y":y};}).on("drag", dragTransparencyFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragTransparencyFunc() {
//console.log(d3.event.x);
//console.log(d3.event.y);
//d3.select(this).attr("x",internalCoordinates[0]).attr("y",internalCoordinates[1]);
//d3.select(this).attr("x",d3.event.x).attr("y",d3.event.y);
var minX = location.iconPadding;
var maxX = location.iconSize*2+location.iconPadding*3;
d3.select(this).attr("x",Math.max(minX,Math.min(d3.event.x,maxX)));
d3.select("#"+ID+"rect").attr("fill-opacity",function(){return (Math.max(minX,Math.min(d3.event.x,maxX))-minX)/(maxX-minX);});
}
//main svg
d3.select("#annotation").append(type).attr("id",ID).attr("x",function(){return parseInt(location.x);}).attr("y",function (){return parseInt(location.y);}).attr("width",function(){return parseInt(location.width);}).attr("height",function(){return parseInt(location.height);}).on("mousemove",function (){internalCoordinates = getInternalCoordinates("#"+ID)});
//background rect
d3.select("#"+ID).append("rect").attr("id",function(){return ID+"rect";}).attr("x",function(){return parseInt(location.width)/2;}).attr("y",function(){return parseInt(location.height)/2;}).attr("width",0).attr("height",0).attr("rx",function(){if(!(location.rx === undefined)){return parseInt(location.rx);}else{return 15;}}).attr("ry",function(){if(!(location.ry === undefined)){return parseInt(location.ry);}else{return 15;}}).attr("fill-opacity",0.25).attr("fill","DimGray");
warp(ID+"rect",location.width,location.height);
//add icons
d3.select("#"+ID).append("svg:image").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"enlarge";}).attr("xlink:href",enlargeWindowIcon).attr("title","enlargeWindowIcon").attr("alt","enlarge").attr("x",function() {return location.iconPadding;}).attr("y",function() {return location.iconPadding;}).attr("width",location.iconSize).attr("height",location.iconSize).style("opacity",0).attr("onmousedown",function(){return "enlargeStartMD(evt,'#"+ID+"')";}).attr("onmousemove",function(){var addionalArguments= ","+JSON.stringify(location);return "enlargeMeMM(evt,'#"+ID+"'"+addionalArguments+")";}).attr("onmouseout",function(){var addionalArguments= ","+JSON.stringify(location)+","+funcToCall+","+JSON.stringify(arg); return "enlargeEndMO(evt,'#"+ID+"'"+addionalArguments+")";}).attr("onmouseup",function(){return "enlargeEndMU(evt,'"+ID+"',"+funcToCall+","+JSON.stringify(arg)+")"}).on("mouseover",function(){iconMagify("enlarge")}).on("mouseout",function(){iconMagify("reset")});
d3.select("#"+ID).append("svg:image").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"relocate";}).attr("xlink:href",relocateWindowIcon).attr("title","relocateWindowIcon").attr("alt","relocate").attr("x",function() {return 2*(location.iconPadding)+location.iconSize;}).attr("y",function() {return location.iconPadding;}).attr("width",location.iconSize).attr("height",location.iconSize).style("opacity",0).on("mouseover",function(){iconMagify("relocate")}).on("mouseout",function(){iconMagify("reset")}).on("click",function(){d3.event.stopPropagation(); relocateWindow = "#"+ID;});
d3.select("#"+ID).append("svg:image").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"drag";}).attr("xlink:href",dragWindowIcon).attr("title","dragWindowIcon").attr("alt","drag").attr("x",function() {return 3*(location.iconPadding)+2*(location.iconSize);}).attr("y",function() {return location.iconPadding;}).attr("width",location.iconSize).attr("height",location.iconSize).style("opacity",0).attr("onmousedown",function(){return "dragStartMD(evt,'#"+ID+"')"}).attr("onmousemove",function(){return "dragMeMM(evt,'#"+ID+"')"}).attr("onmouseout",function(){return "dragEndMO(evt,'#"+ID+"')"}).attr("onmouseup",function(){return "dragEndMU(evt)"}).on("mouseover",function(){iconMagify("drag");}).on("mouseout",function(){iconMagify("reset");});
d3.select("#"+ID).append("svg:image").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"magnify";}).attr("xlink:href",magnifyWindowIcon).attr("title","magnifyWindowIcon").attr("alt","magnify").attr("x",function() {return 4*(location.iconPadding)+3*(location.iconSize);}).attr("y",function() {return location.iconPadding;}).attr("width",location.iconSize).attr("height",location.iconSize).style("opacity",0).on("mouseover",function(){iconMagify("magnify");}).on("mouseout",function(){iconMagify("reset");}).attr("onclick",function(){var addionalArguments= ","+JSON.stringify(location)+",1.1,"+funcToCall+","+JSON.stringify(arg); return "magnifyClick(evt,'#"+ID+"'"+addionalArguments+")";});
d3.select("#"+ID).append("svg:image").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"minify";}).attr("xlink:href",minifyWindowIcon).attr("title","minifyWindowIcon").attr("alt","minify").attr("x",function() {return 5*(location.iconPadding)+4*(location.iconSize);}).attr("y",function() {return location.iconPadding;}).attr("width",location.iconSize).attr("height",location.iconSize).style("opacity",0).on("mouseover",function(){iconMagify("minify");}).on("mouseout",function(){iconMagify("reset");}).attr("onclick",function(){var addionalArguments= ","+JSON.stringify(location)+",0.9,"+funcToCall+","+JSON.stringify(arg); return "magnifyClick(evt,'#"+ID+"'"+addionalArguments+")";});
d3.select("#"+ID).append("svg:image").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"close";}).attr("xlink:href",closeWindowIcon).attr("title","closeWindowIcon").attr("alt","closeWindow").attr("x",function() {return location.width-location.iconPadding-location.iconSize;}).attr("y",function() {return location.iconPadding;}).attr("width",location.iconSize).attr("height",location.iconSize).style("opacity",0).on("mouseover",function(){iconMagify("close")}).on("mouseout",function(){iconMagify("reset")}).on("click",function(){d3.select("#"+ID).remove();});
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"knobTrail";}).attr("x",location.iconPadding).attr("y",function(){return location.height-location.iconPadding+location.iconSize/4-7.5;}).attr("width",location.iconSize*2.5+location.iconPadding*2).attr("height",15).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").style("opacity",0);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"icons";}).attr("id",function(){return ID+"knob";}).attr("x",function(){return (location.iconPadding*11+location.iconSize*6)/5;}).attr("y",function(){return location.height-location.iconPadding;}).attr("width",location.iconSize/2).attr("height",location.iconSize/2).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").style("opacity",0).call(dragTransparency);
d3.select("#"+ID).selectAll(ID+"colorBoxes").data(["DimGray","Black","Red","LightSeaGreen","DodgerBlue","DeepPink"]).enter().append("rect").attr("class",function(){return ID+"icons "+ID+"colorBoxes";}).attr("id",function(d){return ID+d;}).attr("x",function (d,i){return location.width-((6-i)*(location.iconPadding/4+location.iconSize/2))-location.iconPadding*3/4;}).attr("y",function(){return location.height-location.iconPadding;}).attr("width",location.iconSize/2).attr("height",location.iconSize/2).attr("rx",15).attr("ry",15).attr("fill-opacity",0.65).attr("fill",function(d){return d;}).style("opacity",0).on("mouseover",function(d){d3.selectAll("."+ID+"colorBoxes").filter(function(){if (d3.select(this).datum() === d){return 0;}else{return 1;}}).call(generalMinifyRect,location.iconSize/2,location.iconSize/2);d3.select(this).call(generalMagnifyRect,location.iconSize/2,location.iconSize/2);}).on("mouseout",function(){d3.selectAll("."+ID+"colorBoxes").call(generalMinifyRect,location.iconSize,location.iconSize);}).on("click",function(d){d3.select("#"+ID+"rect").transition().attr("fill",function(){return d;}).delay(0).duration(1000);});
//initiate icon fade-in or magnify on mouseover
d3.selectAll("."+ID+"icons").data(["enlarge","relocate","drag","magnify","minify","close","knobTrail","knob","DimGray","Black","Red","LightSeaGreen","DodgerBlue","DeepPink"]).each(function(d,i){d3.select("#"+ID+d).transition().style("opacity",1).delay(i*150+100).duration(i*400+250);});
function iconMagify (iconName) {
d3.selectAll("."+ID+"icons").data(["enlarge","relocate","drag","magnify","minify","close"]).each(function(d,i){
d3.select("#"+ID+d).transition("iconMagnifyWidth").attr("width",function(){if(iconName.match(d)){return 1.5*location.iconSize;}else if(iconName.match("reset")){return location.iconSize;}else{return 0.5*location.iconSize;}}).ease("elastic").delay(0).duration(1000);
d3.select("#"+ID+d).transition("iconMagnifyHeight").attr("height",function(){if(iconName.match(d)){return 1.5*location.iconSize;}else if(iconName.match("reset")){return location.iconSize;}else{return 0.5*location.iconSize;}}).ease("elastic").delay(0).duration(1000);
});
}
function generalMinifyRect(selection,width,height) {
selection.transition("width").attr("width",width/2).ease("elastic").delay(0).duration(1000);
selection.transition("height").attr("height",height/2).ease("elastic").delay(0).duration(1000);
}
function generalMagnifyRect(selection,width,height) {
selection.transition("width").attr("width",width*1.5).ease("elastic").delay(0).duration(1000);
selection.transition("height").attr("height",height*1.5).ease("elastic").delay(0).duration(1000);
}
//call a function
if (funcToCall) {
funcToCall.apply(this,[ID,arg]);
}
}
//",[adjustWindowIcon,"+JSON.stringify(location)+",'#"+ID+"','close']"
//more gateways needed sire! xD..
function warp (ID,width,height) {
//console.log(ID+" "+width+" "+height+" !");
d3.select("#"+ID).transition("adjustX").attr("x",function(){var x = parseInt(d3.select(this).attr("x"));return x-width/2;}).delay(0).duration(500);
d3.select("#"+ID).transition("adjustY").attr("y",function(){var y = parseInt(d3.select(this).attr("y"));return y-height/2;}).delay(0).duration(500);
d3.select("#"+ID).transition("adjustW").attr("width",width).delay(0).duration(500);
d3.select("#"+ID).transition("adjustH").attr("height",height).delay(0).duration(500);
d3.select("#"+ID).transition("adjustFO").attr("fill-opacity",0.6).delay(0).duration(1000);
}
//adjust icon position
function adjustWindowIcon (location,ID,iconName) {
var p = location.iconPadding;
var s = location.iconSize;
var w = location.width;
var iconPlacement = {"enlarge":"p","relocate":"2p+s","drag":"3p+2s","close":"w-s-p"};
d3.select(ID+iconName).attr("x",function() {var x = eval(iconPlacement[iconName]);console.log(x);return x;});
console.log(p+" "+s+" "+w+" "+ID+iconName);
}
//get internal coordinates
function getInternalCoordinates (ID) {
var x = d3.select(ID).attr("x");
var y = d3.select(ID).attr("y");
return [coordinates[0]-x,coordinates[1]-y];
}
<!--Drag mechanism 2 -->
//Global Drag 2 variables that will be automatically refreshed for each new draggable element
var dragOffsetX_2 = 0;
var dragOffsetY_2 = 0;
var dragX_2 = 0;
var dragY_2 = 0;
var mousedown_2 = false;
//Global Drag 2 variables that will be automatically refreshed for each new draggable element
//Supply the drag event handler and also the id of the element to be operated on. stopPropagation() and preventDefault() will cancel accidental text selection if pointer/finger leaves the dragged element area.
function dragStartMD(event,ID) {
//alert(event.target.id);--> Check for id
//alert(event.pageX+","+event.pageY);
event.stopPropagation();
event.preventDefault();
dragX_2 = parseFloat(event.pageX)*4.67-500;
dragY_2 = parseFloat(event.pageY)*4.67-500;
dragOffsetX_2 = dragX_2-parseFloat(d3.select(arguments[1]).attr("x"));
dragOffsetY_2 = dragY_2-parseFloat(d3.select(arguments[1]).attr("y"));
mousedown_2 = true;
}
//Supply the drag event handler and also the id of the element to be operated on.
function dragMeMM(event,ID) {
event.stopPropagation();
event.preventDefault();
if(mousedown_2) {
dragX_2 = parseFloat(event.pageX)*4.67-500;
dragY_2 = parseFloat(event.pageY)*4.67-500;
d3.select(arguments[1]).attr("x",function () {return dragX_2-dragOffsetX_2}).attr("y",function() {return dragY_2-dragOffsetY_2});
}
}
function dragEndMO(event) {
event.stopPropagation();
event.preventDefault();
//mousedown_2 = false;
if(mousedown_2) {
dragX_2 = parseFloat(event.pageX)*4.67-500;
dragY_2 = parseFloat(event.pageY)*4.67-500;
d3.select(arguments[1]).attr("x",function () {return dragX_2-dragOffsetX_2}).attr("y",function() {return dragY_2-dragOffsetY_2});
}
}
function dragEndMU(event) {
event.stopPropagation();
event.preventDefault();
mousedown_2 = false;
}
<!--Drag mechanism 2-->
<!--Enlarge mechanism-->
//shares mostly same global variables with drag mechanism 2
var enlargeFixedDimensions ={"x1":0,"y1":0};
function enlargeStartMD(event,ID) {
event.stopPropagation();
event.preventDefault();
dragX_2 = parseFloat(event.pageX)*4.67-500;
dragY_2 = parseFloat(event.pageY)*4.67-500;
dragOffsetX_2 = dragX_2-parseFloat(d3.select(arguments[1]).attr("x"));
dragOffsetY_2 = dragY_2-parseFloat(d3.select(arguments[1]).attr("y"));
enlargeFixedDimensions.x1 = parseFloat(d3.select(arguments[1]).attr("x"))+parseFloat(d3.select(arguments[1]).attr("width"));
enlargeFixedDimensions.y1 = parseFloat(d3.select(arguments[1]).attr("y"))+parseFloat(d3.select(arguments[1]).attr("height"));
mousedown_2 = true;
}
function enlargeMeMM(event,ID,location,funcToCall,arg) {
event.stopPropagation();
event.preventDefault();
if(mousedown_2) {
var minWidth = location.minWidth;
var minHeight = location.minHeight;
var width = Math.abs(dragX_2-dragOffsetX_2-enlargeFixedDimensions.x1);
var height = Math.abs(dragY_2-dragOffsetY_2-enlargeFixedDimensions.y1);
dragX_2 = parseFloat(event.pageX)*4.67-500;
dragY_2 = parseFloat(event.pageY)*4.67-500;
d3.select(arguments[1]).attr("width",function () {return Math.max(minWidth,width);}).attr("height",function() {return Math.max(minHeight,height);}).attr("x",function () {return Math.min(dragX_2-dragOffsetX_2,enlargeFixedDimensions.x1-minWidth);}).attr("y",function() {return Math.min(dragY_2-dragOffsetY_2,enlargeFixedDimensions.y1-minHeight);});
d3.select(arguments[1]+"rect").attr("width",function () {return Math.max(minWidth,width);}).attr("height",function() {return Math.max(minHeight,height);});
d3.select(arguments[1]+"close").attr("x",function(){return Math.max(minWidth,width)-location.iconPadding-location.iconSize;});
d3.select(arguments[1]+"knob").attr("y",function(){return Math.max(minHeight,height)-location.iconPadding;});
d3.select(arguments[1]+"knobTrail").attr("y",function(){return Math.max(minHeight,height)-location.iconPadding+location.iconSize/4-7.5;});
d3.selectAll(arguments[1].replace("#",".")+"colorBoxes").data(["DimGray","Black","Red","LightSeaGreen","DodgerBlue","DeepPink"]).attr("x",function(d,i){return Math.max(minWidth,width)-((6-i)*(location.iconPadding/4+location.iconSize/2))-location.iconPadding*3/4;}).attr("y",function(){return Math.max(minHeight,height)-location.iconPadding;});
}
}
function enlargeEndMO(event,ID,location,funcToCall,arg) {
event.stopPropagation();
event.preventDefault();
//mousedown_2 = false;
if(mousedown_2) {
var minWidth = location.minWidth;
var minHeight = location.minHeight;
var width = Math.abs(dragX_2-dragOffsetX_2-enlargeFixedDimensions.x1);
var height = Math.abs(dragY_2-dragOffsetY_2-enlargeFixedDimensions.y1);
dragX_2 = parseFloat(event.pageX)*4.67-500;
dragY_2 = parseFloat(event.pageY)*4.67-500;
d3.select(arguments[1]).attr("width",function () {return Math.max(minWidth,width);}).attr("height",function() {return Math.max(minHeight,height);}).attr("x",function () {return Math.min(dragX_2-dragOffsetX_2,enlargeFixedDimensions.x1-minWidth);}).attr("y",function() {return Math.min(dragY_2-dragOffsetY_2,enlargeFixedDimensions.y1-minHeight);});
d3.select(arguments[1]+"rect").attr("width",function () {return Math.max(minWidth,width);}).attr("height",function() {return Math.max(minHeight,height);});
d3.select(arguments[1]+"close").attr("x",function(){return Math.max(minWidth,width)-location.iconPadding-location.iconSize;});
d3.select(arguments[1]+"knob").attr("y",function(){return Math.max(minHeight,height)-location.iconPadding;});
d3.select(arguments[1]+"knobTrail").attr("y",function(){return Math.max(minHeight,height)-location.iconPadding+location.iconSize/4-7.5;});
d3.selectAll(arguments[1].replace("#",".")+"colorBoxes").data(["DimGray","Black","Red","LightSeaGreen","DodgerBlue","DeepPink"]).attr("x",function(d,i){return Math.max(minWidth,width)-((6-i)*(location.iconPadding/4+location.iconSize/2))-location.iconPadding*3/4;}).attr("y",function(){return Math.max(minHeight,height)-location.iconPadding;});
if (funcToCall) {
funcToCall.apply(this,[ID.replace("#",""),arg]);
}
}
}
function enlargeEndMU(event,ID,funcToCall,arg) {
//I comment out propagation because master svg also fires this function on mouse up. This causes the machine to not properly fire mouseup event as a result dragged elements get stuck in mousedown mode.
//event.stopPropagation();
event.preventDefault();
mousedown_2 = false;
//sometimes it gets the object itself rather than the id.
if((ID)&&(funcToCall)) {
if (typeof ID === "object") {
ID = d3.select(ID).attr("id");
funcToCall.apply(this,[ID,arg]);
} else if (typeof ID === "string") {
funcToCall.apply(this,[ID,arg]);
} else {
}
}
}
<!--Enlarge mechanism-->
<!--Magnify/Minify mechanism-->
function magnifyClick(event,ID,location,magnificationRate,funcToCall,arg) {
event.stopPropagation();
event.preventDefault();
var minWidth = location.minWidth;
var minHeight = location.minHeight;
var maxHeight = location.maxHeight;
var maxWidth = location.maxWidth;
//10 percent magnification
var width = parseFloat(d3.select(ID).attr("width"))*magnificationRate;
var height = parseFloat(d3.select(ID).attr("height"))*magnificationRate;
d3.select(arguments[1]).attr("width",function () {return Math.max(minWidth,Math.min(width,maxWidth));}).attr("height",function() {return Math.max(minHeight,Math.min(height,maxHeight));});
d3.select(arguments[1]+"rect").attr("width",function () {return Math.max(minWidth,Math.min(width,maxWidth));}).attr("height",function() {return Math.max(minHeight,Math.min(height,maxHeight));});
d3.select(arguments[1]+"close").attr("x",function(){return Math.max(minWidth,Math.min(width,maxWidth))-location.iconPadding-location.iconSize;});
d3.select(arguments[1]+"knob").attr("y",function(){return Math.max(minHeight,Math.min(height,maxHeight))-location.iconPadding;});
d3.select(arguments[1]+"knobTrail").attr("y",function(){return Math.max(minHeight,Math.min(height,maxHeight))-location.iconPadding+location.iconSize/4-7.5;});
d3.selectAll(arguments[1].replace("#",".")+"colorBoxes").data(["DimGray","Black","Red","LightSeaGreen","DodgerBlue","DeepPink"]).attr("x",function(d,i){return Math.max(minWidth,Math.min(width,maxWidth))-((6-i)*(location.iconPadding/4+location.iconSize/2))-location.iconPadding*3/4;}).attr("y",function(){return Math.max(minHeight,Math.min(height,maxHeight))-location.iconPadding;});
if (funcToCall) {
funcToCall.apply(this,[ID.replace("#",""),arg]);
}
}
<!--Magnify/Minify mechanism-->
<!--WindowInterface-->
<!--Drawing Interface-->
<!--Draw equilateral triangle with given radius measured as the distance from center of gravity to one corner-->
//the x,y and r values are between 0 and 1, they represent the full width and the height of whatever container they are drawn in
function drawEqTriangle (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
currentRadius = Math.min(currentWidth,currentHeight);
d3.select(IDtoDrawOn).append("polygon").attr("points",function(){return (objectHash.x*currentWidth)+","+(objectHash.y*currentHeight-objectHash.radius*currentRadius)+" "+(objectHash.x*currentWidth+objectHash.radius*currentRadius/2*Math.sqrt(3))+","+(objectHash.y*currentHeight+objectHash.radius*currentRadius/2)+" "+(objectHash.x*currentWidth-objectHash.radius*currentRadius/2*Math.sqrt(3))+","+(objectHash.y*currentHeight+objectHash.radius*currentRadius/2);}).attr("filter",function(){if(objectHash.filter){return "url(#NeonGlow)";}else{return null;}}).attr("stroke-linejoin","round").attr("fill",function(){if (objectHash.fill){return objectHash.fill;}else{return "DimGray";}}).attr("fill-opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).attr("stroke",function(){if (objectHash.stroke){return objectHash.stroke;}else{return "DimGray";}}).attr("stroke-opacity",function(){if (objectHash.strokeOpacity){return Math.sqrt(objectHash.strokeOpacity);}else{return 0.71;}}).attr("stroke-width",function(){if (objectHash.width){return objectHash.width;}else{return 2;}}).attr("id",function(){if (objectHash.id){return objectHash.id;}}).attr("class",function(){if (objectHash.class){return objectHash.class;}}).attr("onmouseover",function(){if(objectHash.mouseover){return objectHash.mouseover;}}).attr("onmouseout",function(){if(objectHash.mouseout){return objectHash.mouseout;}}).style("opacity",0).transition().style("opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).delay(function(){if(objectHash.delay){return objectHash.delay;}else{return 0;}}).duration(function(){if(objectHash.duration){return objectHash.duration;}else{return 0;}});
}
<!--Draw equilateral triangle with given radius measured as the distance from center of gravity to one corner-->
<!--Draw hexagon-->
function drawHexagon (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
currentRadius = Math.min(currentWidth,currentHeight);
d3.select(IDtoDrawOn).append("polygon").attr("points",function(){return (objectHash.x*currentWidth+objectHash.radius*currentRadius/2)+","+(objectHash.y*currentHeight-objectHash.radius*currentRadius/2*Math.sqrt(3))+" "+(objectHash.x*currentWidth+objectHash.radius*currentRadius)+","+(objectHash.y*currentHeight)+" "+(objectHash.x*currentWidth+objectHash.radius*currentRadius/2)+","+(objectHash.y*currentHeight+objectHash.radius*currentRadius/2*Math.sqrt(3))+" "+(objectHash.x*currentWidth-objectHash.radius*currentRadius/2)+","+(objectHash.y*currentHeight+objectHash.radius*currentRadius/2*Math.sqrt(3))+" "+(objectHash.x*currentWidth-objectHash.radius*currentRadius)+","+(objectHash.y*currentHeight)+" "+(objectHash.x*currentWidth-objectHash.radius*currentRadius/2)+","+(objectHash.y*currentHeight-objectHash.radius*currentRadius/2*Math.sqrt(3));}).attr("filter",function(){if(objectHash.filter){return "url(#NeonGlow)";}else{return null;}}).attr("stroke-linejoin","round").attr("fill",function(){if (objectHash.fill){return objectHash.fill;}else{return "DimGray";}}).attr("fill-opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).attr("stroke",function(){if (objectHash.stroke){return objectHash.stroke;}else{return "DimGray";}}).attr("stroke-opacity",function(){if (objectHash.strokeOpacity){return Math.sqrt(objectHash.strokeOpacity);}else{return 0.71;}}).attr("stroke-width",function(){if (objectHash.width){return objectHash.width;}else{return 2;}}).attr("id",function(){if (objectHash.id){return objectHash.id;}}).attr("class",function(){if (objectHash.class){return objectHash.class;}}).attr("onmouseover",function(){if(objectHash.mouseover){return objectHash.mouseover;}}).attr("onmouseout",function(){if(objectHash.mouseout){return objectHash.mouseout;}}).style("opacity",0).transition().style("opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).delay(function(){if(objectHash.delay){return objectHash.delay;}else{return 0;}}).duration(function(){if(objectHash.duration){return objectHash.duration;}else{return 0;}});
}
<!--Draw hexagon-->
<!--Draw polygon-->
//within the object hash there will be a points array. All the points in this array are returned with the given offsets. The offsets are between 0 and 1.
function drawPolygon (IDtoDrawOn,objectHash,currentWidth,currentHeight,offsetX,offsetY) {
offsetX = offsetX || 0;
offsetY = offsetY || 0;
d3.select(IDtoDrawOn).append("polygon").attr("points",function(){
var points = "";
for (var i = 0;i < objectHash.points.length;i++) {
points = points+((objectHash.points[i][0]+offsetX)*currentWidth)+","+((objectHash.points[i][1]+offsetY)*currentHeight)+" ";
}
return points;
}).attr("filter",function(){if(objectHash.filter){return "url(#NeonGlow)";}else{return null;}}).attr("stroke-linejoin","round").attr("fill",function(){if (objectHash.fill){return objectHash.fill;}else{return "DimGray";}}).attr("fill-opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).attr("stroke",function(){if (objectHash.stroke){return objectHash.stroke;}else{return "DimGray";}}).attr("stroke-opacity",function(){if (objectHash.strokeOpacity){return Math.sqrt(objectHash.strokeOpacity);}else{return 0.71;}}).attr("stroke-width",function(){if (objectHash.width){return objectHash.width;}else{return 2;}}).attr("id",function(){if (objectHash.id){return objectHash.id;}}).attr("class",function(){if (objectHash.class){return objectHash.class;}}).style("opacity",0).transition().style("opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).delay(function(){if(objectHash.delay){return objectHash.delay;}else{return 0;}}).duration(function(){if(objectHash.duration){return objectHash.duration;}else{return 0;}});
}
<!--Draw polygon-->
<!--Draw circle-->
function drawCircle (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
currentRadius = Math.min(currentWidth,currentHeight);
d3.select(IDtoDrawOn).append("circle").attr("cx",function(){return objectHash.x*currentWidth;}).attr("cy",function(){return objectHash.y*currentHeight;}).attr("r",function(){return objectHash.radius*currentRadius;}).attr("filter",function(){if(objectHash.filter){return "url(#NeonGlow)";}else{return null;}}).attr("fill",function(){if (objectHash.fill){return objectHash.fill;}else{return "DimGray";}}).attr("fill-opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).attr("stroke",function(){if (objectHash.stroke){return objectHash.stroke;}else{return "DimGray";}}).attr("stroke-opacity",function(){if (objectHash.strokeOpacity){return Math.sqrt(objectHash.strokeOpacity);}else{return 0.71;}}).attr("stroke-width",function(){if (objectHash.width){return objectHash.width;}else{return 2;}}).attr("id",function(){if (objectHash.id){return objectHash.id;}}).attr("class",function(){if (objectHash.class){return objectHash.class;}}).attr("onmouseover",function(){if(objectHash.mouseover){return objectHash.mouseover;}}).attr("onmouseout",function(){if(objectHash.mouseout){return objectHash.mouseout;}}).style("opacity",0).transition().style("opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).delay(function(){if(objectHash.delay){return objectHash.delay;}else{return 0;}}).duration(function(){if(objectHash.duration){return objectHash.duration;}else{return 0;}});
}
<!--Draw circle-->
<!--Draw text-->
function drawText (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
currentRadius = Math.min(currentWidth,currentHeight);
d3.select(IDtoDrawOn).append("text").text(function(){if(objectHash.text){return objectHash.text;}else{return "undefined";}}).attr("x",function(){return objectHash.x*currentWidth;}).attr("y",function(){return objectHash.y*currentHeight;}).attr("font-size",function(){if(objectHash.fontSize){return objectHash.fontSize;}else{return "100px";}}).attr("font-family","sans-serif").attr("text-anchor","middle").attr("filter",function(){if(objectHash.filter){return "url(#NeonGlow)";}else{return null;}}).attr("fill",function(){if (objectHash.fill){return objectHash.fill;}else{return "DimGray";}}).attr("fill-opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).attr("stroke",function(){if (objectHash.stroke){return objectHash.stroke;}else{return "DimGray";}}).attr("stroke-opacity",function(){if (objectHash.strokeOpacity){return Math.sqrt(objectHash.strokeOpacity);}else{return 0.71;}}).attr("stroke-width",function(){if (objectHash.width){return objectHash.width;}else{return 2;}}).attr("transform",function(){if(objectHash.transform){return objectHash.transform;}}).attr("id",function(){if (objectHash.id){return objectHash.id;}}).attr("class",function(){if (objectHash.class){return objectHash.class;}}).attr("onmouseover",function(){if(objectHash.mouseover){return objectHash.mouseover;}}).attr("onmouseout",function(){if(objectHash.mouseout){return objectHash.mouseout;}}).style("opacity",0).transition().style("opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).delay(function(){if(objectHash.delay){return objectHash.delay;}else{return 0;}}).duration(function(){if(objectHash.duration){return objectHash.duration;}else{return 0;}});
}
<!--Draw text-->
<!--Draw path-->
function drawPath (IDtoDrawOn,objectHash,currentWidth,currentHeight,funcToCall,args) {
d3.select(IDtoDrawOn).append("path").attr("d",function(){return pathStringGenerator(objectHash,currentWidth,currentHeight);}).attr("filter",function(){if(objectHash.filter){return "url(#NeonGlow)";}else{return null;}}).attr("stroke-linejoin","round").attr("stroke-linecap","round").attr("fill",function(){if (objectHash.fill){return objectHash.fill;}else{return "DimGray";}}).attr("fill-opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).attr("stroke",function(){if (objectHash.stroke){return objectHash.stroke;}else{return "DimGray";}}).attr("stroke-opacity",function(){if (objectHash.strokeOpacity){return Math.sqrt(objectHash.strokeOpacity);}else{return 0.71;}}).attr("stroke-width",function(){if (objectHash.width){return objectHash.width;}else{return 2;}}).attr("id",function(){if (objectHash.id){return objectHash.id;}}).attr("class",function(){if (objectHash.class){return objectHash.class;}}).style("opacity",0).transition("fadein").style("opacity",function(){if (objectHash.opacity){return Math.sqrt(objectHash.opacity);}else{return 0.71;}}).each(function(){if(funcToCall){funcToCall.apply(this,args);}}).delay(function(){if(objectHash.delay){return objectHash.delay;}else{return 0;}}).duration(function(){if(objectHash.duration){return objectHash.duration;}else{return 0;}});
}
function pathStringGenerator(objectHash,currentWidth,currentHeight) {
return "M"+(objectHash.x0*currentWidth)+","+(objectHash.y0*currentHeight)+"L"+(objectHash.x1*currentWidth)+","+(objectHash.y1*currentHeight);
}
function extendPath(ID,objectHash,currentWidth,currentHeight,funcToCall,args) {
d3.select(ID).transition("extend").attrTween("d",function(){var interpolator = d3.interpolateString(pathStringGenerator({x0:objectHash.x0,y0:objectHash.y0,x1:objectHash.x1,y1:objectHash.y1},currentWidth,currentHeight),pathStringGenerator({x0:objectHash.x1,y0:objectHash.y1,x1:objectHash.x2,y1:objectHash.y2},currentWidth,currentHeight));return function(t){return interpolator(t)};}).each("end",function(){if(funcToCall){funcToCall.apply(this,args);}}).delay(function(){if(objectHash.extensionDelay){return objectHash.extensionDelay;}else{return 0;}}).duration(function(){if(objectHash.extensionDuration){return objectHash.extensionDuration;}else{return 0;}});
}
//let the inception begin..
function extendTrailPath(IDtoDrawOn,IDarray,objectHash,trailArray,currentWidth,currentHeight,clear) {
if(clear) {
d3.selectAll(".lotusPathLines").remove();
}
if (IDarray.length !== 0) {
var currentID = IDarray.shift();
var objectHashMirror = objectHash;
var IDarrayMirror = IDarray;
objectHashMirror.x0 = trailArray[0][0];
objectHashMirror.y0 = trailArray[0][1];
objectHashMirror.x1 = trailArray[0][0];
objectHashMirror.y1 = trailArray[0][1];
objectHashMirror.x2 = trailArray[1][0];
objectHashMirror.y2 = trailArray[1][1];
objectHashMirror.id = currentID;
var trailArrayMirror = trailArray;
trailArrayMirror.shift();
drawPath(IDtoDrawOn,objectHashMirror,currentWidth,currentHeight,extendPath,["#"+currentID,objectHashMirror,currentWidth,currentHeight,extendTrailPath,[IDtoDrawOn,IDarrayMirror,objectHashMirror,trailArrayMirror,currentWidth,currentHeight]]);
}
if((IDarray.length < 1)&&(lotusMouseOut)) {
d3.selectAll(".lotusPathLines").remove();
}
}
//the dream collapses..
function collapseTrailPath (IDarray,objectHash,trailArray,currentWidth,currentHeight) {
if ((IDarray.length !== 0)&&(lotusMouseOut)) {
var currentID = IDarray.pop();
var objectHashMirror = objectHash;
var IDarrayMirror = IDarray;
objectHashMirror.x0 = trailArray[trailArray.length-2][0];
objectHashMirror.y0 = trailArray[trailArray.length-2][1];
objectHashMirror.x1 = trailArray[trailArray.length-2][0];
objectHashMirror.y1 = trailArray[trailArray.length-2][1];
var trailArrayMirror = trailArray;
trailArrayMirror.pop();
d3.select("#"+currentID).transition("collapse").attr("d",function(){return pathStringGenerator(objectHash,currentWidth,currentHeight);}).each("end",function(){d3.select(this).remove();if((IDarray.length < 1)&&(lotusMouseOut)){d3.selectAll(".lotusPathLines").remove();};collapseTrailPath(IDarrayMirror,objectHashMirror,trailArrayMirror,currentWidth,currentHeight);}).delay(function(){if(objectHash.extensionDelay){return objectHash.extensionDelay;}else{return 0;}}).duration(function(){if(objectHash.extensionDuration){return objectHash.extensionDuration;}else{return 0;}});
}
}
<!--Draw path-->
<!--Drawing Interface-->
<!--Lotus-->
var lotusMouseOut = false;
//I had to come up with the below function, d3s mouse events fire too late to capture this the way I want..
function lotusMouseOutFunc(status){
status === "1" ? lotusMouseOut = true : lotusMouseOut = false;
}
//clockwise numbering starting from the smallest angle taking 12 o'clock position as 0 degrees. keys mean renderingOrder_number.
var lotusData = {r1n0:{x0:"0.5",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5"},r1n1:{x0:"0.5",y0:"0.5",x1:"0.5-radius/Math.sqrt(7)/2",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r1n2:{x0:"0.5",y0:"0.5",x1:"0.5-radius/Math.sqrt(7)/2",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},
r2n0:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)*1.5",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n1:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)*2",y1:"0.5"},r2n2:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)*1.5",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n3:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n4:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},
r2n5:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n6:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},r2n7:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},r2n8:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*1.5",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n9:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)",y1:"0.5"},
r2n10:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},r2n11:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n12:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)",y1:"0.5"},r2n13:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*1.5",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},r2n14:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},
r3n0:{x0:"0.5",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},r3n1:{x0:"0.5+radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},r3n2:{x0:"0.5+radius/Math.sqrt(7)*1.5",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},
r3n3:{x0:"0.5+radius/Math.sqrt(7)*2",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)*2.5",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},r3n4:{x0:"0.5+radius/Math.sqrt(7)*2",y0:"0.5",x1:"0.5+radius/Math.sqrt(7)*2.5",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},
r3n5:{x0:"0.5+radius/Math.sqrt(7)*1.5",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},r3n6:{x0:"0.5+radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},r3n7:{x0:"0.5",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},
r3n8:{x0:"0.5-radius/Math.sqrt(7)",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)/2",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)*1.5"},r3n9:{x0:"0.5-radius/Math.sqrt(7)",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*2",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},
r3n10:{x0:"0.5-radius/Math.sqrt(7)*1.5",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*2",y1:"0.5"},r3n11:{x0:"0.5-radius/Math.sqrt(7)",y0:"0.5",x1:"0.5-radius/Math.sqrt(7)*2",y1:"0.5"},r3n12:{x0:"0.5-radius/Math.sqrt(7)*1.5",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*2",y1:"0.5"},
r3n13:{x0:"0.5-radius/Math.sqrt(7)",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*2",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},r3n14:{x0:"0.5-radius/Math.sqrt(7)",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)/2",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)*1.5"},
r4n0:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)*1.5"},r4n1:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)*2",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},r4n2:{x0:"0.5+radius/Math.sqrt(7)*2.5",y0:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)*2",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)"},
r4n3:{x0:"0.5+radius/Math.sqrt(7)*2.5",y0:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)*2",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},r4n4:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)*2",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)"},r4n5:{x0:"0.5+radius/Math.sqrt(7)",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)*1.5"},r4n6:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)*1.5",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)*1.5"},
r4n7:{x0:"0.5-radius/Math.sqrt(7)*2",y0:"0.5+radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*2.5",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r4n8:{x0:"0.5-radius/Math.sqrt(7)*2",y0:"0.5",x1:"0.5-radius/Math.sqrt(7)*2.5",y1:"0.5+radius/Math.sqrt(7)/2*Math.sqrt(3)"},r4n9:{x0:"0.5-radius/Math.sqrt(7)*2",y0:"0.5",x1:"0.5-radius/Math.sqrt(7)*2.5",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},r4n10:{x0:"0.5-radius/Math.sqrt(7)*2",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)",x1:"0.5-radius/Math.sqrt(7)*2.5",y1:"0.5-radius/Math.sqrt(7)/2*Math.sqrt(3)"},
r4n11:{x0:"0.5-radius/Math.sqrt(7)/2",y0:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)*1.5",x1:"0.5+radius/Math.sqrt(7)/2",y1:"0.5-radius/Math.sqrt(7)*Math.sqrt(3)*1.5"},
}
//var codonData = {aa:"A",seq:{full:"GCC",base1:{original:"G",alt1:"A",alt2:"T",alt3:"C"},base2:{original:"C",alt4:"G",alt5:"A",alt6:"T"},base3:{original:"C",alt7:"G",alt8:"A",alt9:"T"}},p:100};
//var codonData = {aa:"Y",seq:{full:"TAC",base1:{original:"T",alt1:"C",alt2:"G",alt3:"A"},base2:{original:"A",alt4:"T",alt5:"C",alt6:"G"},base3:{original:"C",alt7:"G",alt8:"A",alt9:"T"}},p:100};
function Lotus(ID,codonData){
d3.selectAll("."+arguments[0]+"drawnElements").remove();
var hashID = "#"+arguments[0];
var currentWidth = parseFloat(d3.select("#"+arguments[0]).attr("width"));
var currentHeight = parseFloat(d3.select("#"+arguments[0]).attr("height"));
var currentDims = Math.min(currentWidth,currentHeight);
var currentOffsetX = currentWidth<=currentHeight ? 0 : (currentWidth-currentHeight)/currentHeight/2;
var currentOffsetY = currentHeight<=currentWidth ? 0 : (currentHeight-currentWidth)/currentWidth/2;
//start the animation
var radius = 0.45;
d3.select("#"+arguments[0])
.selectAll("lotusAnimationElements")
.data(d3.keys(lotusData))
.enter()
.append("path")
.attr("d",function(d,i){
var objectHash = {};
objectHash.x0 = eval(lotusData[d].x0)+currentOffsetX;
objectHash.y0 = eval(lotusData[d].y0)+currentOffsetY;
objectHash.x1 = eval(lotusData[d].x0)+currentOffsetX;
objectHash.y1 = eval(lotusData[d].y0)+currentOffsetY;
return pathStringGenerator(objectHash,currentDims,currentDims);
})
.attr("stroke-width",10)
.attr("stroke","DodgerBlue")
.attr("stroke-opacity",0.85)
.attr("id",function(d){return ID+d;})
.attr("class",function(d){return ID+"drawnElements "+ID+"lotusAnimationLines";})
.transition("extend")
.attr("d",function(d){
var objectHash = {};
objectHash.x0 = eval(lotusData[d].x0)+currentOffsetX;
objectHash.y0 = eval(lotusData[d].y0)+currentOffsetY;
objectHash.x1 = eval(lotusData[d].x1)+currentOffsetX;
objectHash.y1 = eval(lotusData[d].y1)+currentOffsetY;
return pathStringGenerator(objectHash,currentDims,currentDims);
})
.each("end",function(d){
d3.select(this)
.transition("shrink")
.attr("d",function(){
var objectHash = {};
objectHash.x0 = eval(lotusData[d].x1)+currentOffsetX;
objectHash.y0 = eval(lotusData[d].y1)+currentOffsetY;
objectHash.x1 = eval(lotusData[d].x1)+currentOffsetX;
objectHash.y1 = eval(lotusData[d].y1)+currentOffsetY;
return pathStringGenerator(objectHash,currentDims,currentDims);
})
.each("end",function(){
d3.select(this).remove();
})
.delay(function(){
var renderOrder = parseInt(d.replace(/r|n.*/,""));
return (renderOrder-1)*0;
})
.duration(500);
})
.delay(function(d){
var renderOrder = parseInt(d.replace(/r|n.*/,""));
return (renderOrder-1)*250;
})
.duration(1000);
//end the animation
//some common variables
var aaPositions = ["r2n13","r2n14","r2n10","r2n0","r2n1","r2n2","r2n6","r2n7","r2n8"];
var aaSymbols = {Nonpolar:[drawCircle,"Gray"],Polar:[drawCircle,"DeepPink"],Positive:[drawEqTriangle,"Red"],Negative:[drawEqTriangle,"Blue"],Aromatic:[drawHexagon,"Green"]};
var standartObject = {filter:false,radius:0.025,"class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01};//this object is constantly changed by the aa element for-loop.
var standartPolygonObject = {filter:false,radius:0.025,"class":arguments[0]+"drawnElements",opacity:0.5,strokeOpacity:0.8,width:10};//this one as well by the polygon for-loop.
var trailPaths = [["r2n13","r1n2"],["r2n14","r1n2"],["r2n10","r1n2"],["r2n0","r1n0"],["r2n1","r1n0"],["r2n2","r1n0"],["r2n6","r1n1"],["r2n7","r1n1"],["r2n8","r1n1"]];
var polygonPositions = [["r2n12","r3n11","r3n11","r3n12","r2n13"],["r2n13","r3n12","r4n9","r4n9","r4n10","r3n13","r3n14","r4n11","r4n0","r3n0","r2n10"],["r2n10","r3n0","r3n0","r3n1","r2n11"],
["r2n4","r3n1","r3n1","r3n2","r2n0"],["r2n0","r3n2","r4n1","r4n1","r4n2","r3n3","r3n4","r4n3","r4n4","r3n5","r2n2"],["r2n2","r3n5","r3n5","r3n6","r2n3"],
["r2n5","r3n6","r3n6","r3n7","r2n6"],["r2n7","r3n7","r4n5","r4n5","r4n6","r3n8","r3n9","r4n7","r4n8","r3n10","r2n8"],["r2n8","r3n10","r3n10","r3n11","r2n9"]
];
//some common variables
//insert polygons
//first insert the center piece
drawPolygon(hashID,{filter:false,points:segmentToPoints(["r2n4","r2n3","r2n5","r2n9","r2n12","r2n11"]),radius:0.025,id:arguments[0]+"_r1n0_polygon","class":arguments[0]+"drawnElements",opacity:0.5,strokeOpacity:0.8,width:10,fill:aaSymbols[aminoacids[codonData["aa"]][1]][1],stroke:aaSymbols[aminoacids[codonData["aa"]][1]][1],delay:2000,duration:2000},currentDims,currentDims,currentOffsetX,currentOffsetY);
d3.select(hashID+"_r1n0_polygon").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n0"].x0)+currentOffsetX,y:eval(lotusData["r1n0"].y1)+currentOffsetY-standartObject.radius*4,fontSize:(50*currentDims/1200),fill:"Orange",stroke:"Orange",id:"lotusExplanation","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:"original aa: "+aminoacids[codonData["aa"]][1]},currentDims,currentDims);}).on("mouseout",function(){d3.select("#lotusExplanation").remove();d3.select(this).attr("filter",null);});
//first insert the center piece
for (var i = 0; i< aaPositions.length; i++) {
var data = codonData;
var base = "base"+(parseInt(i/3)+1);
var newSeq = calculateNewCodon(i);
var newAA;
var obj = standartPolygonObject;
for (var key in aminoacids_degenerateCode) {
if (aminoacids_degenerateCode[key].some(function(x){return x === newSeq;})){
newAA = key;
break;
}
}
obj.id = ID+"_"+aaPositions[i]+"_polygon";
obj.opacity = 0.5;
obj.strokeOpacity = 0.8;
obj.points = segmentToPoints(polygonPositions[i]);
obj.width = 10;
obj.delay = 2000;
obj.duration = 2000;
//render the polygon
if (newAA !== "X") {
obj.fill = aaSymbols[aminoacids[newAA][1]][1];
obj.stroke = aaSymbols[aminoacids[newAA][1]][1];
drawPolygon(hashID,obj,currentDims,currentDims,currentOffsetX,currentOffsetY);
} else {
obj.fill = "transparent";
obj.stroke = "Brown";
drawPolygon(hashID,obj,currentDims,currentDims,currentOffsetX,currentOffsetY);
}
//render the polygon
d3.select("#"+obj.id).attr("onmouseover",function(){
obj.fill = "Orange";
obj.stroke = "Orange";
obj.opacity = 0.9;
obj.strokeOpacity = 0.01;
if (newAA !== "X") {
obj.text = aminoacids[newAA][1]+" change";
} else {
obj.text = "stop codon";
}
obj.id = "lotusExplanation";
obj.fontSize = 50*currentDims/1200;
obj.width = 2;
obj.x = eval(lotusData[aaPositions[i]].x1)+currentOffsetX;
obj.y = eval(lotusData[aaPositions[i]].y1)+currentOffsetY-standartObject.radius*3;
obj.delay = 0;
obj.duration = 500;
var func1 = "drawText('"+hashID+"',"+JSON.stringify(obj)+","+currentDims+","+currentDims+")";
return func1;
})
.on("mouseout",function(){
d3.select("#lotusExplanation").remove();
d3.select(this).attr("filter",null);
})
.on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");});
}
//each array contains the names of the line segments from lotusData that circumvent the polygon. The order of these segments are clockwise starting from their birth point like in the animation. The polygons themselves are ordered like the aminoacids. First one starting around 10 o'clock position.
function segmentToPoints(array) {
var points = [];
for (var i = 0;i < array.length;i++){
if (checkEquality(points,[eval(lotusData[array[i]].x0),eval(lotusData[array[i]].y0)])) {
points.push([eval(lotusData[array[i]].x1),eval(lotusData[array[i]].y1)]);
} else {
points.push([eval(lotusData[array[i]].x0),eval(lotusData[array[i]].y0)]);
}
}
return points;
function checkEquality(ref,test) {
return ref.some(function(d,i,a){return ((d[0]===test[0])&&(d[1]===test[1]));});
}
}
//insert polygons
//insert aa elements
//first insert the center piece
aaSymbols[aminoacids[codonData["aa"]][1]][0](hashID,{filter:false,radius:0.025*GoldenRatio,x:eval(lotusData["r1n0"].x0)+currentOffsetX,y:eval(lotusData["r1n0"].y1)+currentOffsetY,fill:aaSymbols[aminoacids[codonData["aa"]][1]][1],stroke:aaSymbols[aminoacids[codonData["aa"]][1]][1],id:arguments[0]+"_r1n0","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:1,delay:0,duration:500},currentDims,currentDims);
d3.select(hashID+"_r1n0").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n0"].x0)+currentOffsetX,y:eval(lotusData["r1n0"].y1)+currentOffsetY+standartObject.radius*4,fontSize:(50*currentDims/1200),fill:"Orange",stroke:"Orange",id:"lotusExplanation","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:"original aa: "+codonData["aa"]+" ("+aminoacids[codonData["aa"]][0]+")"},currentDims,currentDims);}).on("mouseout",function(){d3.select("#lotusExplanation").remove();d3.select(this).attr("filter",null);});
//the amino acid number is static
drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n0"].x0)+currentOffsetX,y:eval(lotusData["r1n0"].y1)+currentOffsetY-standartObject.radius*2.5,fontSize:(35*currentDims/1200),fill:"Orange",stroke:"Orange","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:"p."+codonData["p"]},currentDims,currentDims);
drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n0"].x0)+currentOffsetX,y:eval(lotusData["r1n0"].y1)+currentOffsetY+standartObject.radius*0.5,fontSize:(40*currentDims/1200),fill:"Orange",stroke:"Orange","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:"..."+codonData["seq"]["full"]+"..."},currentDims,currentDims);
//first insert the center piece
for (var i = 0; i< aaPositions.length; i++) {
var data = codonData;
var base = "base"+(parseInt(i/3)+1);
var newSeq = calculateNewCodon(i);
var newAA;
var obj = standartObject;
for (var key in aminoacids_degenerateCode) {
if (aminoacids_degenerateCode[key].some(function(x){return x === newSeq;})){
newAA = key;
break;
}
}
obj.x = eval(lotusData[aaPositions[i]].x1)+currentOffsetX;
obj.y = eval(lotusData[aaPositions[i]].y1)+currentOffsetY;
obj.id = ID+"_"+aaPositions[i];
obj.delay = 1000;
obj.duration = 2000;
//render the symbol
if (newAA !== "X") {
obj.fill = aaSymbols[aminoacids[newAA][1]][1];
obj.stroke = aaSymbols[aminoacids[newAA][1]][1];
aaSymbols[aminoacids[newAA][1]][0].call(this,hashID,obj,currentDims,currentDims);
} else {
obj.fill = "Orange";
obj.stroke = "Orange";
obj.fontSize = 75*currentDims/1200;
obj.y = eval(lotusData[aaPositions[i]].y1)+currentOffsetY+standartObject.radius;
obj.text = "X";
drawText.call(this,hashID,obj,currentDims,currentDims);
}
//render the symbol
//define some variables before starting animations with the rendered symbol.
var trailPath = [[eval(lotusData[trailPaths[i][0]].x1)+currentOffsetX,eval(lotusData[trailPaths[i][0]].y1)+currentOffsetY],[eval(lotusData[trailPaths[i][0]].x0)+currentOffsetX,eval(lotusData[trailPaths[i][0]].y0)+currentOffsetY],[eval(lotusData[trailPaths[i][1]].x0)+currentOffsetX,eval(lotusData[trailPaths[i][1]].y0)+currentOffsetY]];
var objPath = {fill:"Orange",stroke:"Orange",strokeOpacity:1,filter:false,"class":ID+"drawnElements lotusPathLines",opacity:1,delay:0,duration:1000,width:20,extensionDuration:150};
d3.select("#"+obj.id).attr("onmouseover",function(){
obj.fill = "Orange";
obj.stroke = "Orange";
if (newAA !== "X") {
obj.text = newAA+" ("+aminoacids[newAA][0]+"): c."+((data["p"]-1)*3+1+Math.floor(i/3))+data["seq"][base]["original"]+">"+data["seq"][base]["alt"+(i+1)];
} else {
obj.text = "stop codon: c."+((data["p"]-1)*3+1+Math.floor(i/3))+data["seq"][base]["original"]+">"+data["seq"][base]["alt"+(i+1)];
}
obj.id = "lotusExplanation";
obj.fontSize = 50*currentDims/1200;
obj.y = eval(lotusData[aaPositions[i]].y1)+currentOffsetY-standartObject.radius*3;
obj.delay = 0;
obj.duration = 500;
var func1 = "drawText('"+hashID+"',"+JSON.stringify(obj)+","+currentDims+","+currentDims+")";
var func2 = "extendTrailPath('"+hashID+"',['lotusPath1','lotusPath2'],"+JSON.stringify(objPath)+","+JSON.stringify(trailPath)+","+currentDims+","+currentDims+","+true+")";
return "lotusMouseOutFunc('0');"+func1+";"+func2;
})
.attr("onmouseout",function(){
var func1 = "collapseTrailPath(['lotusPath1','lotusPath2'],"+JSON.stringify(objPath)+","+JSON.stringify(trailPath)+","+currentDims+","+currentDims+")";
return "lotusMouseOutFunc('1');"+func1;
})
.on("mouseout",function(){
d3.select("#lotusExplanation").remove();
d3.select(this).attr("filter",null);
})
.on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");});
}
//insert aa elements
//insert alt bases
//first insert the original bases
drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n2"].x1)+currentOffsetX,y:eval(lotusData["r1n2"].y1)+currentOffsetY+standartObject.radius,fontSize:(60*currentDims/1200),fill:"Orange",stroke:"Orange","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:codonData["seq"]["base1"]["original"]},currentDims,currentDims);
drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n0"].x1)+currentOffsetX,y:eval(lotusData["r1n0"].y1)+currentOffsetY+standartObject.radius,fontSize:(60*currentDims/1200),fill:"Orange",stroke:"Orange","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:codonData["seq"]["base2"]["original"]},currentDims,currentDims);
drawText(hashID,{filter:false,radius:0.025,x:eval(lotusData["r1n1"].x1)+currentOffsetX,y:eval(lotusData["r1n1"].y1)+currentOffsetY+standartObject.radius,fontSize:(60*currentDims/1200),fill:"Orange",stroke:"Orange","class":arguments[0]+"drawnElements",opacity:0.9,strokeOpacity:0.01,delay:0,duration:500,text:codonData["seq"]["base3"]["original"]},currentDims,currentDims);
//first insert the original bases
for (var i = 0; i< aaPositions.length; i++) {
var data = codonData;
var base = "base"+(parseInt(i/3)+1);
var obj = standartObject;
obj.x = (eval(lotusData[aaPositions[i]].x1)+eval(lotusData[aaPositions[i]].x0))/2+currentOffsetX;
obj.y = (eval(lotusData[aaPositions[i]].y1)+eval(lotusData[aaPositions[i]].y0))/2+currentOffsetY;
obj.id = ID+"_"+aaPositions[i]+"_bases";
obj.delay = 1000;
obj.duration = 2000;
obj.fill = "Orange";
obj.stroke = "Orange";
obj.opacity = 0.9;
obj.strokeOpacity = 0.01;
obj.fontSize = 30*currentDims/1200;
obj.text = data["seq"][base]["alt"+(i+1)];
drawText.call(this,hashID,obj,currentDims,currentDims);
}
//insert alt bases
//var someTestObject = {filter:false,points:[[0.4,0.4],[0.45,0.35],[0.5,0.4],[0.45,0.45],[0.4,0.7]],"class":arguments[0]+"drawnElements",id:"thePolygon",fill:"Orange",stroke:"Orange",opacity:0.9,strokeOpacity:1,delay:0,duration:2000};
//drawPolygon(hashID,someTestObject,currentDims,currentDims,currentOffsetX,currentOffsetY);
function calculateNewCodon(count) {
var base = "base"+(parseInt(count/3)+1);
var baseNumber = (parseInt(count/3));
var codonArray = data["seq"]["full"].split("");
codonArray[baseNumber] = data["seq"][base]["alt"+(count+1)];
var newSeq = codonArray.join("");
return newSeq;
}
//Keep text selection process minimal by disabling selection on lotus elements.
d3.selectAll("."+arguments[0]+"drawnElements").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
}
<!--Lotus-->
<!--Lotus Icon-->
var seqGradualFade;
var lastMouseoverSeqElementID;
var lotusIcon = "data:image/png;base64,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";
function lotusFadein(ID){
if ((lastMouseoverSeqElementID !== ID)||!(d3.select("#lotusIcon").node())) {
clearTimeout(seqGradualFade);
d3.select("#lotusIcon").remove();
var angle = Math.atan(Math.abs((parseFloat(d3.select(ID).attr("y"))-3000)/(parseFloat(d3.select(ID).attr("x"))-3000)));
var x = parseFloat(d3.select(ID).attr("x"))-500*Math.cos(angle)*Math.sign(parseFloat(d3.select(ID).attr("x"))-3000);
var y = parseFloat(d3.select(ID).attr("y"))-500*Math.sin(angle)*Math.sign(parseFloat(d3.select(ID).attr("y"))-3000);
d3.select("#annotation").append("svg:image").attr("xlink:href",lotusIcon).attr("title","lotusIcon").attr("alt","lotusIcon").attr("x",function() {return x;}).attr("y",function() {return y;}).attr("width","100px").attr("height","100px").style("opacity",0).attr("id","lotusIcon").transition("fade").style("opacity",0.9).delay(0).duration(1000);
d3.select("#lotusIcon").on("mouseover",function(){
clearTimeout(seqGradualFade);
d3.select(this).transition("fade").style("opacity",0.9).delay(0).duration(1000);
})
.on("mouseout",function(){
seqGradualFade = setTimeout(function(){d3.select("#lotusIcon").remove();},3000);
d3.select("#lotusIcon").transition("fade").style("opacity",0).delay(0).duration(3000);
})
.on("click",function(){
initiateLotus(ID,x,y);
});
lastMouseoverSeqElementID = ID;
}
clearTimeout(seqGradualFade);
d3.select("#lotusIcon").transition("fade").style("opacity",0.9).delay(0).duration(1000);
}
function lotusFadeout(){
seqGradualFade = setTimeout(function(){d3.select("#lotusIcon").remove();},3000);
d3.select("#lotusIcon").transition("fade").style("opacity",0).delay(0).duration(3000);
}
<!--Lotus Icon-->
<!--Lotus initiator-->
function initiateLotus(ID,x,y){
var location = {"x":x,"y":y,"width":2500,"height":2000,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":1200,"maxWidth":5000,"maxHeight":4000};
var aaNumber = Math.floor(ID.replace(/.*_/i,""));
var codonData = {};
codonData.p = aaNumber;
codonData.aa = d3.select(ID).node().textContent || d3.select(ID).node().innerHTML;
codonData.seq = {};
codonData.seq["full"] = cdna[(aaNumber-1)*3] + cdna[(aaNumber-1)*3+1] + cdna[(aaNumber-1)*3+2];
if (aminoacids_degenerateCode[codonData.aa].some(function(x){return x === codonData.seq["full"];})) {
for (var i = 0;i < 3;i++) {
var iterator = ["A","T","C","G"];
codonData.seq["base"+(i+1)] = {};
codonData.seq["base"+(i+1)]["original"] = cdna[(aaNumber-1)*3+i];
Innermost:
for (var k =0;k<1;) {
var regexp = new RegExp(codonData.seq["base"+(i+1)]["original"],"i");
if (iterator[k].match(regexp)) {
iterator.shift();
break Innermost;
} else {
var x = iterator.shift();
iterator.push(x);
}
//console.log(iterator);
}
for(var j=0;j< 3;j++) {
codonData.seq["base"+(i+1)]["alt"+((i*3)+j+1)] = iterator[j];
}
}
d3.select(ID+"_lotusWindow_").remove();
renderWindow.apply(this,["svg",ID.replace("#","")+"_lotusWindow_",location,Lotus,codonData]);
} else {
alert ("The cdna data does not match with the plotted aminoacid.\nPlease check the integrity of the html file.");
}
}
<!--Lotus initiator-->
<!--Change SNV/tile colors-->
var lastTileSNVcolor = {r:255,g:0,b:0};
var tileDBcolorCounter = 0;
var mutDBcolorCounter = 0;
var domainColorCounter = 0;
d3.select("#annotation").append("text").text("Change SNV colors").attr("x",5950).attr("y",475).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","middle").style("fill","DimGray").attr("id","changeSNVcolorText").attr("class","Options")
.on("mouseover",function () {
d3.select("#changeSNVcolorText").style("fill","Orange");
})
.on("mouseout",function () {
d3.select("#changeSNVcolorText").style("fill","DimGray");
})
.on("click",function() {
var ID = d3.select(this).attr("id")+"_SNVcolorWindow";
var location = {"x":4400,"y":475,"width":2000,"height":1500,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":1500,"maxWidth":4000,"maxHeight":4000};
d3.select("#"+d3.select(this).attr("id")+"_SNVcolorWindow").remove();
renderWindow.apply(this,["svg",ID,location,tileSNVcolorChanger]);
});
d3.select("#annotation").append("text").text("Change Tile colors").attr("x",5950).attr("y",575).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","middle").style("fill","DimGray").attr("id","changeTileColorText").attr("class","Options")
.on("mouseover",function () {
d3.select("#changeTileColorText").style("fill","Orange");
})
.on("mouseout",function () {
d3.select("#changeTileColorText").style("fill","DimGray");
})
.on("click",function() {
var ID = d3.select(this).attr("id")+"_TileColorWindow";
var location = {"x":4400,"y":575,"width":2000,"height":1500,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":1500,"maxWidth":4000,"maxHeight":4000};
d3.select("#"+d3.select(this).attr("id")+"_TileColorWindow").remove();
renderWindow.apply(this,["svg",ID,location,tileSNVcolorChanger]);
});
d3.select("#annotation").append("text").text("Change Domain colors").attr("x",5950).attr("y",675).style("font-family","sans-serif").style("font-size","45px").attr("text-anchor","middle").style("fill","DimGray").attr("id","changeDomainColorText").attr("class","Options")
.on("mouseover",function () {
d3.select("#changeDomainColorText").style("fill","Orange");
})
.on("mouseout",function () {
d3.select("#changeDomainColorText").style("fill","DimGray");
})
.on("click",function() {
var ID = d3.select(this).attr("id")+"_DomainColorWindow";
var location = {"x":4400,"y":675,"width":2000,"height":1500,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":1500,"maxWidth":4000,"maxHeight":4000};
d3.select("#"+d3.select(this).attr("id")+"_DomainColorWindow").remove();
renderWindow.apply(this,["svg",ID,location,tileSNVcolorChanger]);
});
function tileSNVcolorChanger (ID) {
d3.selectAll("."+arguments[0]+"drawnElements").remove();
var knobTrailData = {k1:["0.5-r/Math.sqrt(2)","0.5-ry/Math.sqrt(2)"],k2:["0.5-r/Math.sqrt(2)","0.5"],k3:["0.5-r/Math.sqrt(2)","0.5+ry/Math.sqrt(2)"]};
var currentWidth = parseFloat(d3.select("#"+arguments[0]).attr("width"));
var currentHeight = parseFloat(d3.select("#"+arguments[0]).attr("height"));
var currentDims = Math.min(currentWidth,currentHeight);
var currentOffsetX = currentWidth<=currentHeight ? 0 : (currentWidth-currentHeight)/currentHeight/2;
var currentOffsetY = currentHeight<=currentWidth ? 0 : (currentHeight-currentWidth)/currentWidth/2;
var r = 0.45;
var ry = 0.175;
d3.select("#"+arguments[0])
.selectAll("colorChangersKnobTrails")
.data(d3.keys(knobTrailData))
.enter()
.append("path")
.attr("d",function(d,i){
var objectHash = {};
objectHash.x0 = eval(knobTrailData[d][0]);
objectHash.y0 = eval(knobTrailData[d][1])+currentOffsetY;
objectHash.x1 = eval(knobTrailData[d][0]);
objectHash.y1 = eval(knobTrailData[d][1])+currentOffsetY;
return pathStringGenerator(objectHash,currentDims,currentDims);
})
.attr("stroke-width",10)
.attr("stroke","Orange")
.attr("stroke-opacity",0.85)
.attr("id",function(d){return ID+d;})
.attr("class",function(d){return ID+"drawnElements "+ID+"colorChangerAnimationLines";})
.transition("extend")
.attr("d",function(d,i){
var objectHash = {};
objectHash.x0 = eval(knobTrailData[d][0]);
objectHash.y0 = eval(knobTrailData[d][1])+currentOffsetY;
objectHash.x1 = eval(knobTrailData[d][0])+r/Math.sqrt(2);
objectHash.y1 = eval(knobTrailData[d][1])+currentOffsetY;
return pathStringGenerator(objectHash,currentDims,currentDims);
})
.delay(0)
.duration(1000);
drawPolygon("#"+ID,{filter:false,points:[[0.7,0.3],[0.9,0.3],[0.9,0.7],[0.7,0.7]],id:arguments[0]+"displayWhichColor","class":arguments[0]+"drawnElements",opacity:0.75,strokeOpacity:0.8,width:40,fill:compileCurrentColor(),stroke:compileCurrentColor(),delay:0,duration:1000},currentWidth,currentHeight,0,0);
drawPolygon("#"+ID,{filter:false,points:[[0.4,0.175],[0.4,0.225],[0.35,0.2]],id:arguments[0]+"leftSelector","class":arguments[0]+"drawnElements",opacity:0.75,strokeOpacity:0.8,width:0,fill:"Orange",stroke:"Orange",delay:0,duration:1000},currentWidth,currentHeight,0,0);
drawPolygon("#"+ID,{filter:false,points:[[0.9,0.175],[0.9,0.225],[0.95,0.2]],id:arguments[0]+"rightSelector","class":arguments[0]+"drawnElements",opacity:0.75,strokeOpacity:0.8,width:0,fill:"Orange",stroke:"Orange",delay:0,duration:1000},currentWidth,currentHeight,0,0);
drawText("#"+ID,{filter:false,x:0.8,y:0.5,id:arguments[0]+"applyColor","class":arguments[0]+"drawnElements",fontSize:currentDims/20,opacity:0.75,strokeOpacity:0.8,width:1,fill:"Orange",stroke:"Orange",delay:0,duration:1000,text:"Apply"},currentWidth,currentHeight);
d3.select("#"+arguments[0]+"applyColor").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
drawText("#"+ID,{filter:false,x:0.2,y:0.2,id:arguments[0]+"explanation","class":arguments[0]+"drawnElements",fontSize:currentDims/30,opacity:0.75,strokeOpacity:0.8,width:1,fill:"Orange",stroke:"Orange",delay:0,duration:1000,text:(function(){if(ID.match(/tile/gi)){return "Tile database"}else if (ID.match(/SNV/gi)){return "SNV database"}else{return "Domains"}})()},currentWidth,currentHeight);
d3.select("#"+arguments[0]+"explanation").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
drawText("#"+ID,{filter:false,x:0.65,y:0.2,id:arguments[0]+"displayWhichDB","class":arguments[0]+"drawnElements",fontSize:currentDims/30,opacity:0.75,strokeOpacity:0.8,width:1,fill:"Orange",stroke:"Orange",delay:0,duration:1000,text:(function(){if(ID.match(/tile/gi)){return TileDB[tileDBcolorCounter].slice(0,20)}else if (ID.match(/SNV/gi)){return MutDB[mutDBcolorCounter].slice(0,20)} else {return domainList[domainColorCounter].slice(0,20)}})()},currentWidth,currentHeight);
d3.select("#"+arguments[0]+"displayWhichDB").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
drawText("#"+ID,{filter:false,x:0.1,y:0.9,id:arguments[0]+"reset","class":arguments[0]+"drawnElements",fontSize:currentDims/25,opacity:0.75,strokeOpacity:0.8,width:1,fill:"Orange",stroke:"Orange",delay:0,duration:1000,text:"Reset"},currentWidth,currentHeight);
d3.select("#"+arguments[0]+"reset").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
drawPolygon("#"+ID,{filter:false,points:[[currentX(lastTileSNVcolor.r),0.45-ry/Math.sqrt(2)],[currentX(lastTileSNVcolor.r)+0.01,0.45-ry/Math.sqrt(2)],[currentX(lastTileSNVcolor.r)+0.01,0.55-ry/Math.sqrt(2)],[currentX(lastTileSNVcolor.r),0.55-ry/Math.sqrt(2)]],id:arguments[0]+"redKnob","class":arguments[0]+"drawnElements",opacity:1,strokeOpacity:0.7,width:30,fill:"Red",stroke:"Red",delay:0,duration:1000},currentDims,currentDims,0,currentOffsetY);
drawPolygon("#"+ID,{filter:false,points:[[currentX(lastTileSNVcolor.g),0.45],[currentX(lastTileSNVcolor.g)+0.01,0.45],[currentX(lastTileSNVcolor.g)+0.01,0.55],[currentX(lastTileSNVcolor.g),0.55]],id:arguments[0]+"greenKnob","class":arguments[0]+"drawnElements",opacity:1,strokeOpacity:0.7,width:30,fill:"Green",stroke:"Green",delay:0,duration:1000},currentDims,currentDims,0,currentOffsetY);
drawPolygon("#"+ID,{filter:false,points:[[currentX(lastTileSNVcolor.b),0.45+ry/Math.sqrt(2)],[currentX(lastTileSNVcolor.b)+0.01,0.45+ry/Math.sqrt(2)],[currentX(lastTileSNVcolor.b)+0.01,0.55+ry/Math.sqrt(2)],[currentX(lastTileSNVcolor.b),0.55+ry/Math.sqrt(2)]],id:arguments[0]+"blueKnob","class":arguments[0]+"drawnElements",opacity:1,strokeOpacity:0.7,width:30,fill:"Blue",stroke:"Blue",delay:0,duration:1000},currentDims,currentDims,0,currentOffsetY);
var drag = d3.behavior.drag().origin(function(){var x = Number(d3.select(this).attr("points").split(/\s+/).slice(0,1)[0].split(/,/)[0]);var y = Number(d3.select(this).attr("points").split(/\s+/).slice(0,1)[0].split(/,/)[1]);return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function compileCurrentColor(type) {
if (type !== "stroke") {
return "rgb("+lastTileSNVcolor.r+","+lastTileSNVcolor.g+","+lastTileSNVcolor.b+")";
} else {
var total = lastTileSNVcolor.r+lastTileSNVcolor.g+lastTileSNVcolor.b;
var squareSum = Math.pow(lastTileSNVcolor.r,2)+Math.pow(lastTileSNVcolor.g,2)+Math.pow(lastTileSNVcolor.b,2);
var k = total*1.2/squareSum;
return "rgb("+Math.min(Math.floor(Math.pow(lastTileSNVcolor.r,2)*k),255)+","+Math.min(Math.floor(Math.pow(lastTileSNVcolor.g,2)*k),255)+","+Math.min(Math.floor(Math.pow(lastTileSNVcolor.b,2)*k),255)+")";
}
}
function dragFunc() {
var minX = currentDims*(0.495-r/Math.sqrt(2));
var maxX = currentDims*(0.495);
var point = Math.max(minX,Math.min(d3.event.x,maxX));
var yUpper = Number(d3.select(this).attr("points").split(/\s+/).slice(0,1)[0].split(/,/)[1]);
d3.select(this).attr("points",function(){return point+","+yUpper+" "+(point+0.01*currentDims)+","+yUpper+" "+(point+0.01*currentDims)+","+(yUpper+0.1*currentDims)+" "+point+","+(yUpper+0.1*currentDims)});
lastTileSNVcolor[d3.select(this).attr("id").match(/red|blue|green/ig)[0].slice(0,1)] = Math.floor((point/currentDims-0.495+r/Math.sqrt(2))*255/(r/Math.sqrt(2)));
d3.select("#"+ID+"displayWhichColor").attr("fill",function () {return compileCurrentColor();}).attr("stroke", function () {return compileCurrentColor();});
}
function currentX(value){
return r/Math.sqrt(2)*(value/255-1)+0.495;
}
d3.select("#"+arguments[0]+"redKnob").call(drag);
d3.select("#"+arguments[0]+"redKnob").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);});
d3.select("#"+arguments[0]+"greenKnob").call(drag);
d3.select("#"+arguments[0]+"greenKnob").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);});
d3.select("#"+arguments[0]+"blueKnob").call(drag);
d3.select("#"+arguments[0]+"blueKnob").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);});
d3.select("#"+arguments[0]+"displayWhichColor").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);}).on("click",function(){colorFilter(ID);});
d3.select("#"+arguments[0]+"applyColor").on("mouseover",function(){d3.select("#"+ID+"displayWhichColor").attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select("#"+ID+"displayWhichColor").attr("filter",null);}).on("click",function(){colorFilter(ID);});
d3.select("#"+arguments[0]+"leftSelector").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);}).on("click",function(){selector(ID,"left");});
d3.select("#"+arguments[0]+"rightSelector").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);}).on("click",function(){selector(ID,"right");});
d3.select("#"+arguments[0]+"reset").on("mouseover",function(){d3.select(this).attr("filter","url(#NeonGlow)");}).on("mouseout",function(){d3.select(this).attr("filter",null);}).on("click",function(){colorFilter(ID,"reset");});
function colorFilter(ID,reset){
var selected;
if (reset !== "reset") {
if(ID.match(/tile/gi)) {
selected = TileDB[tileDBcolorCounter];
d3.selectAll(".tile").data(ids["tile"]).each(function(d,i) {var database_source = d3.select(ids["tile"][i]).attr("dbsource");var id = d3.select(ids["tile"][i]).attr("id");var regexp = new RegExp(selected,"i");d3.select(d).transition("changeColor").style("fill",function (){if((database_source.match(regexp) || id.match(regexp) || (selected == "All"))&&(selected != "None")){return compileCurrentColor();} else {return d3.select(this).style("fill");}}).delay(0).duration(750);});
} else if (ID.match(/SNV/gi)) {
selected = MutDB[mutDBcolorCounter];
d3.selectAll(".mut").data(ids["mut"]).each(function(d,i) {var database_source = d3.select(ids["mut"][i]).attr("dbsource");var regexp = new RegExp(selected,"i");d3.select(d).transition("changeColor").style("fill",function (){if((database_source.match(regexp) || (selected == "All") || ((selected == "Stop")&&(d3.select(ids["mut"][i]).attr("id").match(/x/i))) || (selected.match(/synonymous/gi)&&(selected===synOrNonsyn(d))) || (selected==="pXtoY" && pXtoY(d)))&&(selected != "None")){return compileCurrentColor();} else {return d3.select(this).style("fill");}}).delay(0).duration(750);});
} else {
selected = domainList[domainColorCounter]==="Coil"?"allCons":domainList[domainColorCounter];
d3.selectAll(".allCons").data(ids["con"]).each(function(d,i) {var clss = d3.select(ids["con"][i]).attr("class").split(" ")[0];var regexp = new RegExp(selected,"i");d3.select(d).transition("changeColor").style("fill",function (){if(clss.match(regexp) || selected==="All"){return compileCurrentColor();} else {return d3.select(this).style("fill");}}).delay(0).duration(750);d3.select(d).transition("changeStrokeColor").style("stroke",function (){if(clss.match(regexp) || selected==="All"){return compileCurrentColor("stroke");} else {return d3.select(this).style("stroke");}}).delay(0).duration(750);});
}
} else {
if(ID.match(/tile/gi)) {
selected = TileDB[tileDBcolorCounter];
d3.selectAll(".tile").data(ids["tile"]).each(function(d,i) {var database_source = d3.select(ids["tile"][i]).attr("dbsource");var id = d3.select(ids["tile"][i]).attr("id");var regexp = new RegExp(selected,"i");d3.select(d).transition("changeColor").style("fill",function (){if((database_source.match(regexp) || id.match(regexp) || (selected == "All"))&&(selected != "None")){return Or_Tile_Fill_Color[i];} else {return d3.select(this).style("fill");}}).delay(0).duration(750);});
} else if (ID.match(/SNV/gi)) {
selected = MutDB[mutDBcolorCounter];
d3.selectAll(".mut").data(ids["mut"]).each(function(d,i) {var database_source = d3.select(ids["mut"][i]).attr("dbsource");var regexp = new RegExp(selected,"i");d3.select(d).transition("changeColor").style("fill",function (){if((database_source.match(regexp) || (selected == "All") || ((selected == "Stop")&&(d3.select(ids["mut"][i]).attr("id").match(/x/i))) || (selected.match(/synonymous/gi)&&(selected===synOrNonsyn(d))) || (selected==="pXtoY" && pXtoY(d)))&&(selected != "None")){return Or_Mut_Fill_Color[i];} else {return d3.select(this).style("fill");}}).delay(0).duration(750);});
} else {
selected = domainList[domainColorCounter]==="Coil"?"allCons":domainList[domainColorCounter];
d3.selectAll(".allCons").data(ids["con"]).each(function(d,i) {var clss = d3.select(ids["con"][i]).attr("class").split(" ")[0];var regexp = new RegExp(selected,"i");d3.select(d).transition("changeColor").style("fill",function (){if(clss.match(regexp) || selected==="All"){return Or_Con_Fill_Color[i];} else {return d3.select(this).style("fill");}}).delay(0).duration(750);d3.select(d).transition("changeStrokeColor").style("stroke",function (){if(clss.match(regexp) || selected==="All"){return Or_Con_Stroke_Color[i];} else {return d3.select(this).style("stroke");}}).delay(0).duration(750);});
}
}
}
function selector(ID,direction) {
if (direction==="left") {
if(ID.match(/tile/gi)){
tileDBcolorCounter = tileDBcolorCounter === 0?TileDB.length-1:tileDBcolorCounter-1;
d3.select("#"+ID+"displayWhichDB").transition("textShuffle").tween("text",function(){var start = lexicalInterpolate(d3.select("#"+ID+"displayWhichDB").text(),1);var end = lexicalInterpolate(TileDB[tileDBcolorCounter],1);var interpolator = d3.interpolateString(start,end);return function(t){this.textContent=lexicalInterpolate(interpolator(t),0)};}).delay(0).duration(500);
}else if (ID.match(/SNV/gi)) {
mutDBcolorCounter = mutDBcolorCounter === 0?MutDB.length-1:mutDBcolorCounter-1;
d3.select("#"+ID+"displayWhichDB").transition("textShuffle").tween("text",function(){var start = lexicalInterpolate(d3.select("#"+ID+"displayWhichDB").text(),1);var end = lexicalInterpolate(MutDB[mutDBcolorCounter],1);var interpolator = d3.interpolateString(start,end);return function(t){this.textContent=lexicalInterpolate(interpolator(t),0)};}).delay(0).duration(500);
} else {
domainColorCounter = domainColorCounter === 0?domainList.length-1:domainColorCounter-1;
d3.select("#"+ID+"displayWhichDB").transition("textShuffle").tween("text",function(){var start = lexicalInterpolate(d3.select("#"+ID+"displayWhichDB").text(),1);var end = lexicalInterpolate(domainList[domainColorCounter],1);var interpolator = d3.interpolateString(start,end);return function(t){this.textContent=lexicalInterpolate(interpolator(t),0)};}).delay(0).duration(500);
}
} else {
if(ID.match(/tile/gi)){
tileDBcolorCounter = tileDBcolorCounter === TileDB.length-1?0:tileDBcolorCounter+1;
d3.select("#"+ID+"displayWhichDB").transition("textShuffle").tween("text",function(){var start = lexicalInterpolate(d3.select("#"+ID+"displayWhichDB").text(),1);var end = lexicalInterpolate(TileDB[tileDBcolorCounter],1);var interpolator = d3.interpolateString(start,end);return function(t){this.textContent=lexicalInterpolate(interpolator(t),0)};}).delay(0).duration(500);
}else if (ID.match(/SNV/gi)) {
mutDBcolorCounter = mutDBcolorCounter === MutDB.length-1?0:mutDBcolorCounter+1;
d3.select("#"+ID+"displayWhichDB").transition("textShuffle").tween("text",function(){var start = lexicalInterpolate(d3.select("#"+ID+"displayWhichDB").text(),1);var end = lexicalInterpolate(MutDB[mutDBcolorCounter],1);var interpolator = d3.interpolateString(start,end);return function(t){this.textContent=lexicalInterpolate(interpolator(t),0)};}).delay(0).duration(500);
} else {
domainColorCounter = domainColorCounter === domainList.length-1?0:domainColorCounter+1;
d3.select("#"+ID+"displayWhichDB").transition("textShuffle").tween("text",function(){var start = lexicalInterpolate(d3.select("#"+ID+"displayWhichDB").text(),1);var end = lexicalInterpolate(domainList[domainColorCounter],1);var interpolator = d3.interpolateString(start,end);return function(t){this.textContent=lexicalInterpolate(interpolator(t),0)};}).delay(0).duration(500);
}
}
}
}
function lexicalInterpolate(given,direction){
var alphabet = {A:1,a:1,B:2,b:2,C:3,c:3,D:4,d:4,E:5,e:5,F:6,f:6,G:7,g:7,H:8,h:8,I:9,i:9,J:10,j:10,K:11,k:11,L:12,l:12,M:13,m:13,N:14,n:14,O:15,o:15,P:16,p:16,Q:17,q:17,R:18,r:18,S:19,s:19,T:20,t:20,U:21,u:21,V:22,v:22,W:23,w:23,X:24,x:24,Y:25,y:25,Z:26,z:26,_:27,"-":28,"(":29,")":30,"[":31,"]":32,"*":33,"&":34,"#":35,"<":36,">":37,"0":38,"1":39,"2":40,"3":41,"4":42,"5":43,"6":44,"7":45,"8":46,"9":47};
var alphabetReverse = {0:"a",1:"a",2:"b",3:"c",4:"d",5:"e",6:"f",7:"g",8:"h",9:"i",10:"j",11:"k",12:"l",13:"m",14:"n",15:"o",16:"p",17:"q",18:"r",19:"s",20:"t",21:"u",22:"v",23:"w",24:"x",25:"y",26:"z",27:"_",28:"-",29:"(",30:")",31:"[",32:"]",33:"*",34:"&",35:"#",36:"<",37:">",38:"0",39:"1",40:"2",41:"3",42:"4",43:"5",44:"6",45:"7",46:"8",47:"9"};
var result;
if (direction===1) {
result = "";
var a = given.split("");
for (var i=0;i<a.length;i++){
if (i !== a.length-1) {
result += alphabet[a[i]]+",";
} else {
result += alphabet[a[i]];
}
}
return result;
} else {
result = "";
given = given.split(",");
for (var i=0;i<given.length;i++){
result += alphabetReverse[Math.floor(given[i])];
}
return result;
}
}
<!--Change SNV/tile colors-->
<!--New Modes for SNV db (MutDB)-->
function synOrNonsyn (d){
var text = d3.select(d).text();
text = text.replace("p.","");
var X = text.slice(0,1);
var Y = text.slice(-1);
if (X === Y) {
return "Synonymous";
} else {
return "Nonsynonymous";
}
}
function pXtoY (d) {
var text = d3.select(d).text();
text = text.replace(/\s*p\./,"");
var X = text.slice(0,1);
var Y = text.slice(-1);
var WhatsClickedSequence = [];
for (var i=0;i<d3.keys(aminoacids).length;i++) {
if(aminoacids[d3.keys(aminoacids)[i]][2]=="Clicked") {
WhatsClickedSequence.push(d3.keys(aminoacids)[i]);
}
}
return WhatsClickedSequence.some(function(x){return x===X;}) && queryAA(AminoAcidProperties[AminoAcidPropertiesCount]).some(function(y){return y===Y});
}
function queryAA (property) {
var result = [];
if (property !== "Sequence Display" && property !== "All") {
d3.keys(aminoacids).forEach(function(d,i){if(aminoacids[d].some(function(x){return x === property && !(result.some(function(x){return x===d;}))})){result.push(d);}});
d3.keys(aminoacids_OtherProperties).forEach(function(d,i){if(aminoacids_OtherProperties[d].some(function(x){return x === property && !(result.some(function(x){return x===d;}))})){result.push(d);}});
} else if (property === "All") {
result = d3.keys(aminoacids);
} else {
for (var i=0;i<WhatsClicked.length;i++) {
result.push(WhatsClicked[i]);
}
}
return result;
}
<!--New Modes for SNV db (MutDB)-->
<!--Ordinator-->
function ordinatorRotate (pointArray,angleArray) {
var sin = Math.sin;
var cos = Math.cos;
var angleToRadian = Math.PI*2/360;
var zeta = angleArray[0]*angleToRadian;
var beta = angleArray[1]*angleToRadian;
var theta = angleArray[2]*angleToRadian;
var x = pointArray[0];
var y = pointArray[1];
var z = pointArray[2];
var xPrime =(x*cos(theta)*cos(beta)+y*cos(beta)*sin(theta)-z*sin(beta));
var yPrime = (x*(cos(theta)*sin(beta)*sin(zeta)-sin(theta)*cos(zeta))+y*(cos(theta)*cos(zeta)+sin(theta)*sin(beta)*sin(zeta))+z*cos(beta)*sin(zeta));
var zPrime = (x*(sin(theta)*sin(zeta)+cos(theta)*cos(zeta)*sin(beta))+y*(cos(zeta)*sin(theta)*sin(beta)-cos(theta)*sin(zeta))+z*cos(beta)*cos(zeta));
var resultArray = [0,0,0,0];
resultArray[0] = xPrime;
resultArray[1] = yPrime;
resultArray[2] = zPrime;
resultArray[3] = pointArray[3];
return resultArray;
}
function ordinatorMap2D(pointArray) {
var sin = Math.sin;
var cos = Math.cos;
zAngle = Math.PI/2;
var z = pointArray[2];
var x = (pointArray[0]-z*cos(zAngle));
var y = (pointArray[1]+z*sin(zAngle));
var resultArray = [0,0,0];
resultArray[0] = x;
resultArray[1] = y;
resultArray[2] = pointArray[3];
return resultArray;
}
function ordinatorFetchData (X,Y,Z) {
//The below hash has a duplicate in the ordinator function.
var aminoacidsX = {"A":["Alanine","Nonpolar"],"R":["Arginine","Positive"],"N":["Asparagine","Polar"],"D":["Aspartic-Acid","Negative"],"C":["Cysteine","Polar"],"Q":["Glutamine","Polar"],"E":["Glutamic-Acid","Negative"],"G":["Glycine","Nonpolar"],"H":["Histidine","Positive"],"I":["Isoleucine","Nonpolar"],"L":["Leucine","Nonpolar"],"K":["Lysine","Positive"],"M":["Methionine","Nonpolar"],"F":["Phenylalanine","Aromatic"],"P":["Proline","Nonpolar"],"S":["Serine","Polar"],"T":["Threonine","Polar"],"W":["Tryptophan","Aromatic"],"Y":["Tyrosine","Aromatic"],"V":["Valine","Nonpolar"],"X":["Stop","Stop"]};
//has a copy in the global scope as well
var aminoacids_OtherProperties = {"A":["Hydrophobic","Aliphatic"],"R":["Hydrophilic","H-bonding","Basic","Ionizable"],"N":["Hydrophilic"],"D":["Hydrophilic","H-bonding","Acidic","Ionizable"],"C":["Hydrophilic","H-bonding","Sulfur-containing","Acidic","Ionizable","Disulfide-bond"],"Q":["Hydrophilic","H-bonding"],"E":["Hydrophilic","H-bonding","Acidic","Ionizable"],"G":["Hydrophobic","Aliphatic"],"H":["Hydrophilic","H-bonding","Basic","Ionizable","All-aromatic"],"I":["Hydrophobic","Aliphatic"],"L":["Hydrophobic","Aliphatic"],"K":["Hydrophilic","H-bonding","Basic","Ionizable"],"M":["Hydrophobic","Sulfur-containing"],"F":["Hydrophobic","All-aromatic"],"P":["Hydrophobic","Aliphatic","Cyclic"],"S":["Hydrophilic","H-bonding"],"T":["Hydrophilic","H-bonding"],"W":["Hydrophobic","H-bonding","All-aromatic"],"Y":["Hydrophobic","H-bonding","Ionizable","All-aromatic"],"V":["Hydrophobic","Aliphatic"]};
//store precomputed values
!ordinatorFetchData.preComputed ? ordinatorFetchData.preComputed = {} : void(0);
//options for different functions to choose from
var options = {
polyphen2:polyphen2,
sift:sift,
position:getPos,
chemicalType:getType,
altType:getAltType,
AAtype:getAAtype,
altAAtype:getAltAAtype,
hydro:hydro,
altHydro:altHydro,
avgPrediction:getAvgScore,
aaChange:getAAchangeScore,
domain:getDomainType,
customdb:getCustomDB,
MAF:getMAF,
conservation:getConservation,
aggregateFeature:aggregateFeature,
hist1:hist1,
hist2:hist2,
hist3:hist3
};
//conservation
var minMaxCons = [0,0];
for (var i =0;i<ids["con"].length;i++){
minMaxCons[0] = +ids["con"][i].replace(/.*_/,"") < minMaxCons[0]? +ids["con"][i].replace(/.*_/,""):minMaxCons[0];
minMaxCons[1] = +ids["con"][i].replace(/.*_/,"") > minMaxCons[1]? +ids["con"][i].replace(/.*_/,""):minMaxCons[1];
}
//for uploaded files. The registeredHistograms look like this: [[[ArrayOfPoints],ID],..]. New files are unshifted, old ones are popped. Max array length is 3.
var hist1 =[];
var hist2 =[];
var hist3 =[];
var offset = registeredHistogramID-registeredHistograms.length;
for (var i = 1;i<4;i++) {
if(registeredHistograms.filter(function(d){return d[1]===((i+offset+3)%3)})[0] !== undefined) {
//console.log("passed");
eval("hist"+i+" = registeredHistograms.filter(function(d){return d[1]==="+((i+offset+3)%3)+"})[0][0]");
}
}
var checkSum = (hist1.length+hist2.length+hist3.length-(ids["con"].length*3))%(ids["con"].length);
if (checkSum !== 0) {
alert("Some of your histogram(s) may have different number of rows than the residue count. Please correct the files and reupload them.");
}
var minMaxHist1 = [0,0];
var minMaxHist2 = [0,0];
var minMaxHist3 = [0,0];
for (var i =0;i<ids["con"].length;i++){
minMaxHist1[0] = +hist1[i] < minMaxHist1[0]? +hist1[i] : minMaxHist1[0];
minMaxHist1[1] = +hist1[i] > minMaxHist1[1]? +hist1[i] : minMaxHist1[1];
minMaxHist2[0] = +hist2[i] < minMaxHist2[0]? +hist2[i] : minMaxHist2[0];
minMaxHist2[1] = +hist2[i] > minMaxHist2[1]? +hist2[i] : minMaxHist2[1];
minMaxHist3[0] = +hist3[i] < minMaxHist3[0]? +hist3[i] : minMaxHist3[0];
minMaxHist3[1] = +hist3[i] > minMaxHist3[1]? +hist3[i] : minMaxHist3[1];
}
//populate points
var args = {points:[],labels:[],labelNames:[]};
ids["mut"].forEach(function(d,i){
args.points.push([options[X](d),-options[Y](d),options[Z](d),i]);
});
//populate labels
for (var i=0;i<3;i++) {
args.labels.push(options[arguments[i]](0,"label"));
args.labelNames.push(arguments[i]);
}
return args;
//different functions below, retreived from the options hash
function polyphen2(element,type) {
if (type !== "label" && (Number(d3.select(element).attr("polyphen2"))>=0)) {
return Number(d3.select(element).attr("polyphen2"));
} else if (type !== "label") {
return -0.5;
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function sift(element,type) {
if (type !== "label" && (Number(d3.select(element).attr("sift"))>=0)) {
return Math.round((1-Number(d3.select(element).attr("sift")))*1000)/1000;
} else if (type !== "label") {
return -0.5;
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function getPos(element,type) {
if (type !== "label") {
return Math.round(parseInt(d3.select(element).attr("id").slice(1))/fasta_sorted.length*1000)/1000;
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function getType(element,type) {
if (type !== "label") {
return ({"Nonpolar":0.167,"Polar":0.334,"Negative":0.501,"Positive":0.668,"Aromatic":0.835})[aminoacids[d3.select(element).attr("id").slice(0,1)][1]];
} else {
return ["Nonpolar","Polar","Negative","Positive","Aromatic","Stop"];
}
}
function getAltType(element,type) {
if (type !== "label" && d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1) !== "X") {
return ({"Nonpolar":0.167,"Polar":0.334,"Negative":0.501,"Positive":0.668,"Aromatic":0.835})[aminoacids[d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1)][1]];
} else if (type !== "label") {
return 1.0;
} else {
return ["Nonpolar","Polar","Negative","Positive","Aromatic","Stop"];
}
}
function getAAtype(element,type) {
if (type !== "label") {
return Math.round((1/d3.keys(aminoacids).length*(d3.keys(aminoacids).sort().indexOf(d3.select(element).attr("id").slice(0,1))+1))*1000)/1000;
} else {
return d3.keys(aminoacids).sort();
}
}
function getAltAAtype(element,type) {
//I had a copy of aminoacidsX hash but X comes before Y, so I decided to put the nonsense muts in the end. But the length of aminoacidsX will be the same as array so no need to replace that.
var array = d3.keys(aminoacids).sort();
array.push("X");
if (type !== "label") {
return Math.round((1/d3.keys(aminoacidsX).length*(array.indexOf(d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1))+1))*1000)/1000;
} else {
return array;
}
}
function getAvgScore(element,type) {
var totalScore = 0;
var count = 0;
if (type !== "label") {
d3.keys(predictionDatabase).forEach(function(d,i){
if(predictionDatabase[d][2] !== "inverse") {
if (Number(d3.select(element).attr(predictionDatabase[d][0]))-predictionDatabase[d][1] >= 0) {
totalScore+= (Number(d3.select(element).attr(predictionDatabase[d][0]))-predictionDatabase[d][1])/(1-predictionDatabase[d][1]);
count++;
} else if (d3.select(element).attr(predictionDatabase[d][0]) !== "NA") {
count++;
}
} else {
if (predictionDatabase[d][1]-Number(d3.select(element).attr(predictionDatabase[d][0])) >= 0) {
totalScore+= (predictionDatabase[d][1]-Number(d3.select(element).attr(predictionDatabase[d][0])))/(predictionDatabase[d][1]);
count++;
} else if (d3.select(element).attr(predictionDatabase[d][0]) !== "NA") {
count++;
}
}
});
if (totalScore >= 0 && count !== 0) {
return Math.round(totalScore/count*1000)/1000;
} else {
return -0.5;
}
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function getAAchangeScore(element,type) {
//The below matrix is arbitrarily set with intention to create least number of classes based on coarse chemical property. It is a diagonal matrix with the row reading: Nonpolar-Polar-Negative-Positive-Aromatic. Use it with caution.
var substitutionMatrix =
[[0,0.25,0.5,0.5,0.25],
[0.25,0,0.5,0.5,0.25],
[0.5,0.5,0,0.75,0.5],
[0.5,0.5,0.75,0,0.5],
[0.25,0.25,0.5,0.5,0]];
var types = {"Nonpolar":0,"Polar":1,"Negative":2,"Positive":3,"Aromatic":4};
if (type !== "label" && d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1) !== "X") {
return substitutionMatrix[types[aminoacids[d3.select(element).attr("id").replace(/_rsID.*/,"").slice(0,1)][1]]][types[aminoacids[d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1)][1]]];
} else if (type !== "label") {
return 1;
} else {
return [0.25,0.5,0.75,1];
}
}
function getDomainType(element,type) {
var array = domainList.filter(function(d,i){return d !=="All"}).sort();
if (type !== "label" && d3.select(ids["con"][parseInt(d3.select(element).attr("id").slice(1))-1]).attr("class").split(" ")[0] !== "allCons") {
return 1/(domainList.length-1)*(array.indexOf(d3.select(ids["con"][parseInt(d3.select(element).attr("id").slice(1))-1]).attr("class").split(" ")[0])+1);
} else if (type !== "label") {
if (domainList.length > 1) {
return 1/(domainList.length-1)*(array.indexOf("Coil")+1);
} else {
return 1;
}
} else {
return array;
}
}
function getCustomDB (element,type) {
var array = MutDB.filter(function(d,i){return d.match(/customdb/i)}).sort();
if (type !== "label" && MutDB.some(function(d,i){return d.match(/customdb/i)})) {
if (array.indexOf(d3.select(element).attr("dbsource")) !== -1) {
return 1/array.length*(array.indexOf(d3.select(element).attr("dbsource"))+1);
} else {
return -0.5;
}
} else if (type !== "label") {
//alert("Non of your variants have a database source ('dbsource') attribute starting with the 'customdb' keyword.\nTherefore all points on this axis will receive a score of -0.5.");
return -0.5;
} else {
if (array.length <= 0) {
return [" "];
} else {
return array;
}
}
}
function getMAF (element,type) {
if (type !== "label") {
var frequency = +d3.select(element).attr("ipvMAF") || +d3.select(element).attr("ipvmaf");
if (frequency < 0) {
frequency = 0;
} else if (frequency > 1) {
frequency = 1;
} else if (String(frequency).match(/na/gi)) {
frequency = -0.5;
}
return frequency;
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function getConservation (element,type) {
if (type !== "label") {
var score = +ids["con"][parseInt(d3.select(element).attr("id").slice(1))-1].replace(/.*_/,"");
return Math.round((score-minMaxCons[0])/(minMaxCons[1]-minMaxCons[0])*1000)/1000;
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function hist1 (element,type) {
if(type !== "label") {
if (hist1.length === ids["con"].length) {
var score = hist1[parseInt(d3.select(element).attr("id").slice(1))-1];
return Math.round((score-minMaxHist1[0])/(minMaxHist1[1]-minMaxHist1[0])*1000)/1000;
} else {
return -0.5;
}
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function hist2 (element,type) {
if(type !== "label") {
if (hist2.length === ids["con"].length) {
var score = hist2[parseInt(d3.select(element).attr("id").slice(1))-1];
return Math.round((score-minMaxHist2[0])/(minMaxHist2[1]-minMaxHist2[0])*1000)/1000;
} else {
return -0.5;
}
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function hist3 (element,type) {
if(type !== "label") {
if (hist3.length === ids["con"].length) {
var score = hist3[parseInt(d3.select(element).attr("id").slice(1))-1];
return Math.round((score-minMaxHist3[0])/(minMaxHist3[1]-minMaxHist3[0])*1000)/1000;
} else {
return -0.5;
}
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function hydro (element,type) {
if (type !== "label") {
if(aminoacids_OtherProperties[d3.select(element).attr("id").slice(0,1)].some(function(x){return x==="Hydrophilic"})) {
return 1;
} else if (aminoacids_OtherProperties[d3.select(element).attr("id").slice(0,1)].some(function(x){return x==="Hydrophobic"})) {
return 0.5;
} else {
return -0.5;
}
} else {
return ["Hydrophobic","Hydrophilic"];
}
}
function altHydro (element,type) {
if (type !== "label") {
if (d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1)==="X") {
return -0.5;
}else if(aminoacids_OtherProperties[d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1)].some(function(x){return x==="Hydrophilic"})) {
return 1;
} else if (aminoacids_OtherProperties[d3.select(element).attr("id").replace(/_rsID.*/,"").slice(-1)].some(function(x){return x==="Hydrophobic"})) {
return 0.5;
} else {
return -0.5;
}
} else {
return ["Hydrophobic","Hydrophilic"];
}
}
function aggregateFeature (element,type) {
if (type !== "label") {
return (ordinatorFetchData.preComputed.segmentVector || initAggregation())[parseInt(d3.select(element).attr("id").slice(1))-1];
} else {
return [0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1.0];
}
}
function initAggregation () {
var matrixColumns = ["Nonpolar","Polar","Positive","Negative","Aromatic","All-aromatic","Aliphatic","Cyclic","Hydrophobic","Hydrophilic","Acidic","Basic","Ionizable","H-bonding","Disulfide-bond","Sulfur-containing"].sort();
(function(){
var array = d3.keys(aminoacidsX).sort();
array.splice(-2,1);
for (var i =array.length-1;i>=0;i--){
matrixColumns.unshift(array[i]);
}
})();
var segmentVector = [];
var _ceiling_ = Math.PI*Math.PI/3;
for (var i=0,total=_ceiling_;i<fasta_sorted.length;i++) {
total=_ceiling_;
for (var j=1;j<11;j++) {
if(i-j>=0) {
total -= vecDist(calculateRow(fasta_sorted[i]),calculateRow(fasta_sorted[i-j]))/13/Math.pow(j,2);
}
if(i+j<fasta_sorted.length) {
total -= vecDist(calculateRow(fasta_sorted[i]),calculateRow(fasta_sorted[i+j]))/13/Math.pow(j,2);
}
}
segmentVector[i] = +(total/_ceiling_).toFixed(2);
}
return ordinatorFetchData.preComputed.segmentVector = segmentVector;
function calculateRow(a){
var vector = [];
for (var i=0;i<matrixColumns.length;i++){
if (a===matrixColumns[i] || aminoacidsX[a].some(function(d){return d===matrixColumns[i]}) || aminoacids_OtherProperties[a].some(function(d){return d===matrixColumns[i]})) {
vector.push(1);
} else {
vector.push(0);
}
}
return vector;
}
function vecDist(vec1,vec2) {
var result = 0;
for (var i=0;i<vec1.length;i++) {
result += Math.abs(vec1[i]-vec2[i]);
}
return result;
}
}
}
//keep a reference to update setInterval functions
var intervalButtons;
var intervalHighlight;
function ordinator(ID,args){
var labels = args.labels;
var labelNames = args.labelNames;
var points = args.points;
//Just keep reference to show x,y,z values when mouseover, also correct the y axis
var pointsRef = [];
points.forEach(function(d,i){pointsRef[i]= [d[0],-d[1],d[2]];});
//get rid of any trace lines if any
d3.select("#"+ID+"_traceLine").remove();
//get rid of any previoulsy opened function windows
d3.select("#"+ID+"_func").remove();
//get rid of any previously initiated setIntervals and registerLinkBoxes
d3.selectAll(".ordinator_"+ID+"_registerLinkBoxes").remove();
clearInterval(intervalButtons);
clearInterval(intervalHighlight);
//below, same as in Lotus function.
var aaSymbols = {Nonpolar:[_drawCircle_,"Gray"],Polar:[_drawCircle_,"DeepPink"],Positive:[_drawEqTriangle_,"Red"],Negative:[_drawEqTriangle_,"Blue"],Aromatic:[_drawHexagon_,"Green"],Stop:[_drawText_,"Orange"]};
//a copy of the aminoacids hash, it has X
var aminoacidsX = {"A":["Alanine","Nonpolar"],"R":["Arginine","Positive"],"N":["Asparagine","Polar"],"D":["Aspartic-Acid","Negative"],"C":["Cysteine","Polar"],"Q":["Glutamine","Polar"],"E":["Glutamic-Acid","Negative"],"G":["Glycine","Nonpolar"],"H":["Histidine","Positive"],"I":["Isoleucine","Nonpolar"],"L":["Leucine","Nonpolar"],"K":["Lysine","Positive"],"M":["Methionine","Nonpolar"],"F":["Phenylalanine","Aromatic"],"P":["Proline","Nonpolar"],"S":["Serine","Polar"],"T":["Threonine","Polar"],"W":["Tryptophan","Aromatic"],"Y":["Tyrosine","Aromatic"],"V":["Valine","Nonpolar"],"X":["Stop","Stop"]};
//extract the wildtype and the mutated amino acids
var wildtypeAndMutated = [];
ids["mut"].forEach(function(d,i){var wtMt = [];wtMt.push(d.slice(1,2));wtMt.push(d.replace(/_rsID.*/,"").slice(-1));wildtypeAndMutated.push(wtMt);});
//extract the point names from ids, saves bit of computation
var pointNames = [];
var pointLocations = [];
ids["mut"].forEach(function(d,i){pointNames.push(d.replace(/\#|_rsID.*/g,""));pointLocations.push(parseInt(d.slice(2)))});
//keep reference to the volumes/links if any
var links = [];
var linksColors = [];
var linksAlphas = [];
var linkCounter = 0;
//tracks whether the user is linking or just started linking
var linkingStatus = 0;
var glyphOrigin = 0;
var dragStartX;
var dragStartY;
var currentRotateX = 0;
var currentRotateY = 45;
var currentRotateZ = 0;
var width = Number(d3.select("#"+ID).attr("width"));
var height = Number(d3.select("#"+ID).attr("height"));
var wTimesH = width*height;
var widthTranslate = 1/2;
var heightTranslate = 1/2;
var widthScale = 1/3;
var heightScale = 1/6;
var fontSize = wTimesH/70000;
var glyphMultiplier = 1;
var showTraceLine = 0;
var showLabels = 0;
//***Filter parameters***
var regions = [(1+fasta_sorted.length)/2-25,(1+fasta_sorted.length)/2+25];
//amino acid keys for filtering [[wildtype],[mutated]]
var filterAA = [[],[]];
(function(){var array = d3.keys(aminoacids);var arrayX = d3.keys(aminoacidsX);array.forEach(function(d,i){filterAA[0][i]=[d,"on"];});arrayX.forEach(function(d,i){filterAA[1][i]=[d,"on"];})})();
var filterNA = 1;
var filterSynonymous = 1;
//***Filter parameters***
//***filter the points before you render them***
args = filterOrdinator(points);
//***filter the points before you render them***
//store//
//aaSymbols[aminoacidsX[wildtypeAndMutated[points[i][3]][glyphOrigin]][1]][0]
var stored = [wildtypeAndMutated.map(function(d,i){return aaSymbols[aminoacidsX[d[0]][1]][0]}),wildtypeAndMutated.map(function(d,i){return aaSymbols[aminoacidsX[d[1]][1]][0]})];
var storedColor = [wildtypeAndMutated.map(function(d,i){return aaSymbols[aminoacidsX[d[0]][1]][1]}),wildtypeAndMutated.map(function(d,i){return aaSymbols[aminoacidsX[d[1]][1]][1]})];
//store//
//Drawing API, exclusive to Indoril/Ordinator
<!--Draw equilateral triangle with given radius measured as the distance from center of gravity to one corner-->
//the x,y and r values are between 0 and 1, they represent the full width and the height of whatever container they are drawn in
function _drawEqTriangle_ (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
var currentRadius = Math.min(currentWidth,currentHeight);
var r = objectHash[0];
var x = objectHash[1];
var y = objectHash[2];
//d3.select(IDtoDrawOn).append("polygon").attr("points",function(){return (x*currentWidth)+","+(y*currentHeight-r*currentRadius)+" "+(x*currentWidth+r*currentRadius/2*Math.sqrt(3))+","+(y*currentHeight+r*currentRadius/2)+" "+(x*currentWidth-r*currentRadius/2*Math.sqrt(3))+","+(y*currentHeight+r*currentRadius/2);}).attr("stroke-linejoin","round").attr("fill",objectHash[3]).attr("fill-opacity",objectHash[5]).attr("stroke",objectHash[4]).attr("stroke-opacity",objectHash[5]).attr("stroke-width",2).attr("id",objectHash[8]).attr("class","ordinatorPoints").attr("onmouseover",objectHash[9]).attr("onmouseout",objectHash[10]);
shapeMaker.make("polygon",IDtoDrawOn)("points",(x*currentWidth)+","+(y*currentHeight-r*currentRadius)+" "+(x*currentWidth+r*currentRadius/2*Math.sqrt(3))+","+(y*currentHeight+r*currentRadius/2)+" "+(x*currentWidth-r*currentRadius/2*Math.sqrt(3))+","+(y*currentHeight+r*currentRadius/2))("stroke-linejoin","round")("fill",objectHash[3])("fill-opacity",objectHash[5])("stroke",objectHash[4])("stroke-opacity",objectHash[5])("stroke-width",2)("id",objectHash[8])("class","ordinatorPoints")("onmouseover",objectHash[9])("onmouseout",objectHash[10]);
}
<!--Draw equilateral triangle with given radius measured as the distance from center of gravity to one corner-->
<!--Draw hexagon-->
function _drawHexagon_ (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
var currentRadius = Math.min(currentWidth,currentHeight);
var r = objectHash[0];
var x = objectHash[1];
var y = objectHash[2];
//d3.select(IDtoDrawOn).append("polygon").attr("points",function(){return (x*currentWidth+r*currentRadius/2)+","+(y*currentHeight-r*currentRadius/2*Math.sqrt(3))+" "+(x*currentWidth+r*currentRadius)+","+(y*currentHeight)+" "+(x*currentWidth+r*currentRadius/2)+","+(y*currentHeight+r*currentRadius/2*Math.sqrt(3))+" "+(x*currentWidth-r*currentRadius/2)+","+(y*currentHeight+r*currentRadius/2*Math.sqrt(3))+" "+(x*currentWidth-r*currentRadius)+","+(y*currentHeight)+" "+(x*currentWidth-r*currentRadius/2)+","+(y*currentHeight-r*currentRadius/2*Math.sqrt(3));}).attr("stroke-linejoin","round").attr("fill",objectHash[3]).attr("fill-opacity",objectHash[5]).attr("stroke",objectHash[4]).attr("stroke-opacity",objectHash[5]).attr("stroke-width",2).attr("id",objectHash[8]).attr("class","ordinatorPoints").attr("onmouseover",objectHash[9]).attr("onmouseout",objectHash[10]);
shapeMaker.make("polygon",IDtoDrawOn)("points",(x*currentWidth+r*currentRadius/2)+","+(y*currentHeight-r*currentRadius/2*Math.sqrt(3))+" "+(x*currentWidth+r*currentRadius)+","+(y*currentHeight)+" "+(x*currentWidth+r*currentRadius/2)+","+(y*currentHeight+r*currentRadius/2*Math.sqrt(3))+" "+(x*currentWidth-r*currentRadius/2)+","+(y*currentHeight+r*currentRadius/2*Math.sqrt(3))+" "+(x*currentWidth-r*currentRadius)+","+(y*currentHeight)+" "+(x*currentWidth-r*currentRadius/2)+","+(y*currentHeight-r*currentRadius/2*Math.sqrt(3)))("stroke-linejoin","round")("fill",objectHash[3])("fill-opacity",objectHash[5])("stroke",objectHash[4])("stroke-opacity",objectHash[5])("stroke-width",2)("id",objectHash[8])("class","ordinatorPoints")("onmouseover",objectHash[9])("onmouseout",objectHash[10]);
}
<!--Draw hexagon-->
<!--Draw circle-->
function _drawCircle_ (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
var currentRadius = Math.min(currentWidth,currentHeight);
var r = objectHash[0];
var x = objectHash[1];
var y = objectHash[2];
//d3.select(IDtoDrawOn).append("circle").attr("cx",x*currentWidth).attr("cy",y*currentHeight).attr("r",r*currentRadius).attr("fill",objectHash[3]).attr("fill-opacity",objectHash[5]).attr("stroke",objectHash[4]).attr("stroke-opacity",objectHash[5]).attr("stroke-width",2).attr("id",objectHash[8]).attr("class","ordinatorPoints").attr("onmouseover",objectHash[9]).attr("onmouseout",objectHash[10]);
shapeMaker.make("circle",IDtoDrawOn)("cx",x*currentWidth)("cy",y*currentHeight)("r",r*currentRadius)("fill",objectHash[3])("fill-opacity",objectHash[5])("stroke",objectHash[4])("stroke-opacity",objectHash[5])("stroke-width",2)("id",objectHash[8])("class","ordinatorPoints")("onmouseover",objectHash[9])("onmouseout",objectHash[10]);
}
<!--Draw circle-->
<!--Draw text-->
function _drawText_ (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
var currentRadius = Math.min(currentWidth,currentHeight);
var r = objectHash[0];
var x = objectHash[1];
var y = objectHash[2];
//d3.select(IDtoDrawOn).append("text").text(objectHash[6]).attr("x",x*currentWidth).attr("y",y*currentHeight).attr("font-size",objectHash[7]).attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill",objectHash[3]).attr("fill-opacity",objectHash[5]).attr("stroke",objectHash[4]).attr("stroke-opacity",objectHash[5]).attr("stroke-width",2).attr("id",objectHash[8]).attr("class","ordinatorPoints").attr("onmouseover",objectHash[9]).attr("onmouseout",objectHash[10]);
shapeMaker.make("text",IDtoDrawOn)("x",x*currentWidth)("y",y*currentHeight)("font-size",objectHash[7])("font-family","sans-serif")("text-anchor","middle")("fill",objectHash[3])("fill-opacity",objectHash[5])("stroke",objectHash[4])("stroke-opacity",objectHash[5])("stroke-width",2)("id",objectHash[8])("class","ordinatorPoints")("onmouseover",objectHash[9])("onmouseout",objectHash[10])().textContent = objectHash[6];
}
<!--Draw text-->
<!--Path string generator-->
function pathStringGenerator(objectHash,currentWidth,currentHeight) {
return "M"+(objectHash[0]*currentWidth)+","+(objectHash[1]*currentHeight)+"L"+(objectHash[2]*currentWidth)+","+(objectHash[3]*currentHeight);
}
<!--Path string generator-->
<!--Draw axis text-->
function _drawAxisText_ (IDtoDrawOn,objectHash,currentWidth,currentHeight) {
var currentRadius = Math.min(currentWidth,currentHeight);
var x = objectHash[0];
var y = objectHash[1];
//d3.select(IDtoDrawOn).append("text").text(objectHash[5]).attr("x",x*currentWidth).attr("y",y*currentHeight).attr("font-size",objectHash[6]).attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill",objectHash[2]).attr("fill-opacity",objectHash[4]).attr("stroke",objectHash[3]).attr("stroke-opacity",objectHash[4]).attr("stroke-width",2).attr("transform",objectHash[7]);
shapeMaker.make("text",IDtoDrawOn)("x",x*currentWidth)("y",y*currentHeight)("font-size",objectHash[6])("font-family","sans-serif")("text-anchor","middle")("fill",objectHash[2])("fill-opacity",objectHash[4])("stroke",objectHash[3])("stroke-opacity",objectHash[4])("stroke-width",2)("transform",objectHash[7] || "")().textContent = objectHash[5];
}
<!--Draw axis text-->
//Drawing API, exclusive to Indoril/Ordinator
//Container for the 3D points
d3.select("#"+ID).append("g").attr("id",ID+"_ordinatorPointsContainer");
d3.select("#"+ID).append("g").attr("id",ID+"_ordinatorAxesContainer");
var container = "#"+ID+"_ordinatorPointsContainer";
var containerAxes = "#"+ID+"_ordinatorAxesContainer";
var containerElem = d3.select(container).node();
var containerAxesElem = d3.select(containerAxes).node();
//Container for the 3D points
//An alternative to d3 for making elements 1 by 1
var shapeMaker = (function(){
function maker(){
var _this_ = this;
this.attr = function(name,value){if (!name){return this;}this.setAttribute(name,value);return _this_.attr.bind(this);} ;
this.make = function(el,containerNode){var el = document.createElementNS("http://www.w3.org/2000/svg",el); containerNode.appendChild(el); return this.attr.bind(el)};
}
return new maker;
})()
//An alternative to d3 for making elements 1 by 1
renderAxes._ready_ = true;
renderGlyphs._ready_ = true;
renderOrdinatorGUI (ID);
renderAxes([0,45,0]);
renderGlyphs(args,[0,45,0]);
var dragOrdinator = d3.behavior.drag().on("drag", dragOrdinatorFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();dragStartX=coordinates[0];dragStartY=coordinates[1];}).on("dragend",function(){currentRotateX = (currentRotateX+(coordinates[1]-dragStartY)/height*360)%360;currentRotateY = (currentRotateY-(coordinates[0]-dragStartX)/width*360)%360;});
function dragOrdinatorFunc() {
var rotateY = currentRotateY-(+d3.event.x-dragStartX)/width*360;
var rotateX = currentRotateX+(+d3.event.y-dragStartY)/height*360;
d3.select("#"+ID+"_renderXrotate_knob").attr("x",function(){var x = rotateX % 360; if (x < 0){return 220-400/360*x;}else{return 220-400/360*(-360+x);}});
d3.select("#"+ID+"_renderYrotate_knob").attr("x",function(){var x = rotateY % 360; if (x < 0){return width-620-400/360*x;}else{return width-620-400/360*(-360+x);}});
renderAxes([rotateX,rotateY,currentRotateZ],1);
renderGlyphs(args,[rotateX,rotateY,currentRotateZ]);
}
d3.select("#"+ID).call(dragOrdinator);
function renderAxes(angleArray,refresh) {
if(renderAxes._ready_){
window.requestAnimationFrame(function(){
while(containerAxesElem.hasChildNodes()) {
containerAxesElem.removeChild(containerAxesElem.lastChild);
}
d3.select(containerAxes).selectAll("ordinatorAxes").data([[1.1,0,0],[0,-1.1,0],[0,0,1.1]]).enter()
.append("path")
.attr("d",function(d,i){
if (refresh) {
return pathStringGenerator([widthTranslate,heightTranslate,ordinatorMap2D(ordinatorRotate(d,angleArray))[0]*widthScale+widthTranslate,ordinatorMap2D(ordinatorRotate(d,angleArray))[1]*heightScale+heightTranslate],width,height);
} else {
return pathStringGenerator([widthTranslate,heightTranslate,widthTranslate,heightTranslate],width,height);
}
})
.attr("stroke-width",10)
.attr("stroke","Orange")
.attr("fill","Orange")
.style("opacity",0.75)
.style("marker-end","url(#markerTriangle)")
.attr("class","ordinatorAxes");
if(!refresh){
d3.selectAll(".ordinatorAxes")
.transition("fadein")
.attr("d",function(d,i){return pathStringGenerator([widthTranslate,heightTranslate,ordinatorMap2D(ordinatorRotate(d,angleArray))[0]*widthScale+widthTranslate,ordinatorMap2D(ordinatorRotate(d,angleArray))[1]*heightScale+heightTranslate],width,height);})
.delay(0)
.duration(1000);
}
if (showLabels ===1){
var i = 3;
while (i--) {
var length = labels[i].length;
var j = length;
//Label name placement is better than fixed as below-->drawText("#"+ID,returnObject(labelNames[i],i,(length+1),length),width,height);
_drawAxisText_(containerAxesElem,returnObject(labelNames[i],i,12,10),width,height);
while (j--) {
_drawAxisText_(containerAxesElem,returnObject(labels[i][j],i,j,length),width,height);
}
}
}
renderAxes._ready_ = true;
})
}
renderAxes._ready_ = false;
//[0]->x,[1]->y,[2]->fill,[3]->stroke,[4]->opacity,[5]->text,[6]->fontSize,[7]->transform
function returnObject (point,indexAxis,indexPoint,labelCount) {
var rotated = [0,0,0];
if (indexAxis === 0) {
rotated = ordinatorRotate([(indexPoint+1)*1/labelCount, -0.1,-0.1],angleArray);
} else if (indexAxis === 1) {
rotated = ordinatorRotate([-0.1,-(indexPoint+1)*1/labelCount,-0.1],angleArray);
} else {
rotated = ordinatorRotate([-0.1,0.1,(indexPoint+1)*1/labelCount],angleArray);
}
var mapped = ordinatorMap2D(rotated);
var x = mapped[0]*widthScale+widthTranslate;
var y = mapped[1]*heightScale+heightTranslate;
var transform = null;
if (indexAxis === 0) {
transform = "rotate(-45,"+x*width+","+y*height+")";
} else if (indexAxis === 2) {
transform = "rotate(45,"+x*width+","+y*height+")";
}
var glyphObject = [0,0,"0","0",0,"0",0,"0"];
//x
glyphObject[0] = x;
//y
glyphObject[1] = y;
//fill
glyphObject[2] = "Orange";
//stroke
glyphObject[3] = "Orange";
//opacity
glyphObject[4] = 0.4+(rotated[2]+1)/2*0.6;
//text
glyphObject[5] = point;
//fontSize
glyphObject[6] = fontSize/2;
//transform
glyphObject[7] = transform;
return glyphObject;
}
}
function renderGlyphs (args,angleArray) {
if(renderGlyphs._ready_){
window.requestAnimationFrame(function() {
var points = [];
var length = args.length;
var i = length;
while (i--) {
points[i] = ordinatorRotate(args[i],angleArray);
}
points.sort(function(a,b){return b[2]-a[2]});
while(containerElem.hasChildNodes()) {
containerElem.removeChild(containerElem.lastChild);
}
i = length;
while (i--) {
stored[glyphOrigin][points[i][3]](containerElem,returnObject(points[i]),width,height);
registerClick(i);
}
if (showTraceLine===1) {
drawTraceLine(args,angleArray,1);
}
renderPseudoPoly(angleArray);
renderGlyphs._ready_ = true;
function registerClick (index) {
document.getElementById("ordinatorPoint_"+ID+"_"+points[index][3]).addEventListener("click",function(){registerLinks(points[index])},false);
}
})
}
renderGlyphs._ready_ = false;
//[0]->radius,[1]->x,[2]->y,[3]->fill,[4]->stroke,[5]->opacity,[6]->text,[7]->fontSize,[8]->id
//[9]->mouseover,[10]->mouseout
function returnObject (point) {
var id = "ordinatorPoint_"+ID+"_"+point[3];
var mapped = ordinatorMap2D(point);
var x = mapped[0]*widthScale+widthTranslate;
var y = mapped[1]*heightScale+heightTranslate;
var color = storedColor[glyphOrigin][point[3]];
var text = wildtypeAndMutated[point[3]];
var glyphObject = [0,0,0,"0","0",0,"0",0,"0","0","0"];
//radius
glyphObject[0] = (0.005+(point[2]+2)/3*0.005)*glyphMultiplier;
//x
glyphObject[1] = x;
//y
glyphObject[2] = y;
//fill
glyphObject[3] = color;
//stroke
glyphObject[4] = color;
//opacity
glyphObject[5] = 0.4+(point[2]+1)/2*0.6;
//text
glyphObject[6] = text[1];
//fontSize
glyphObject[7] = fontSize;
//id
glyphObject[8] = id;
//mouseover
glyphObject[9] = "d3.select('#ordinatorPointsTextLabel').remove();d3.select('#"+id+"').attr('stroke-width',25).attr('stroke','Orange');d3.select('#"+ID+"').append('text').text('p."+pointNames[point[3]]+" ("+pointsRef[point[3]]+")"+"').attr('id','ordinatorPointsTextLabel').attr('x',"+(x>1/2?x-0.05:x+0.05)*width+").attr('y',"+(y>1/2?y-0.05:y+0.05)*height+").attr('font-size',"+fontSize+").attr('font-family','sans-serif').attr('fill','AntiqueWhite').attr('text-anchor','middle');";
//mouseout
glyphObject[10] = "d3.select('#"+id+"').attr('stroke-width',2).attr('stroke','"+color+"');d3.select('#ordinatorPointsTextLabel').remove();";
return glyphObject;
}
}
function renderOrdinatorGUI (ID) {
renderXrotate(ID);
renderYrotate(ID);
renderZrotate(ID);
renderSlider(ID);
renderAADials(ID,0);
renderAADials(ID,1);
renderAAmassDials (ID,0);
renderAAmassDials (ID,1);
renderShowModules(ID);
renderSizeControls(ID);
//***axes functions***
function renderXrotate (ID) {
d3.selectAll("."+ID+"_renderXrotate").remove();
d3.select("#"+ID).append("path").attr("class",function(){return ID+"_renderXrotate";}).attr("d","M100,307 A50,50 0 1,1 150,357").style("marker-end","url(#markerTriangle)").attr("stroke-opacity",0).attr("stroke-width",4).attr("fill-opacity",0).attr("stroke","Orange").transition("fadein").attr("stroke-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text("x").attr("class",function(){return ID+"_renderXrotate";}).attr("x",150).attr("y",315).attr("font-size","60px").attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderXrotate";}).attr("x",220).attr("y",300).attr("width",400).attr("height",15).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobXpos = Math.max(220,Math.min(620,d3.event.x));
d3.select(this).attr("x",knobXpos);
var rotateX = -(knobXpos-220)/400*360;
currentRotateX = rotateX;
renderAxes([rotateX,currentRotateY,currentRotateZ],1);
renderGlyphs(args,[rotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderXrotate";}).attr("id",function(){return ID+"_renderXrotate_knob";}).attr("x",220).attr("y",282).attr("width",50).attr("height",50).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").call(drag);
}
function renderYrotate (ID) {
d3.selectAll("."+ID+"_renderYrotate").remove();
d3.select("#"+ID).append("path").attr("class",function(){return ID+"_renderYrotate";}).attr("d",function(){var x = width-750; return "M"+x+",307 A50,50 0 1,1 "+(x+50)+",357"}).style("marker-end","url(#markerTriangle)").attr("stroke-opacity",0).attr("stroke-width",4).attr("fill-opacity",0).attr("stroke","Orange").transition("fadein").attr("stroke-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text("y").attr("class",function(){return ID+"_renderYrotate";}).attr("x",function(){return width-700;}).attr("y",315).attr("font-size","60px").attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderYrotate";}).attr("x",function(){return width-620;}).attr("y",300).attr("width",400).attr("height",15).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var xMin = width-620;
var knobYpos = Math.max(xMin,Math.min(xMin+400,d3.event.x));
d3.select(this).attr("x",knobYpos);
var rotateY = -(knobYpos-xMin)/400*360;
currentRotateY = rotateY;
renderAxes([currentRotateX,rotateY,currentRotateZ],1);
renderGlyphs(args,[currentRotateX,rotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderYrotate";}).attr("id",function(){return ID+"_renderYrotate_knob";}).attr("x",function(){return width-620;}).attr("y",282).attr("width",50).attr("height",50).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").call(drag);
}
function renderZrotate (ID) {
d3.selectAll("."+ID+"_renderZrotate").remove();
d3.select("#"+ID).append("path").attr("class",function(){return ID+"_renderZrotate";}).attr("d","M100,607 A50,50 0 1,1 150,657").style("marker-end","url(#markerTriangle)").attr("stroke-opacity",0).attr("stroke-width",4).attr("fill-opacity",0).attr("stroke","Orange").transition("fadein").attr("stroke-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text("z").attr("class",function(){return ID+"_renderZrotate";}).attr("x",150).attr("y",615).attr("font-size","60px").attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderZrotate";}).attr("x",150).attr("y",685).attr("width",15).attr("height",800).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobZpos = Math.max(667,Math.min(667+800,d3.event.y));
d3.select(this).attr("y",knobZpos);
var rotateZ = -(knobZpos-667)/800*360;
currentRotateZ = rotateZ;
renderAxes([currentRotateX,currentRotateY,rotateZ],1);
renderGlyphs(args,[currentRotateX,currentRotateY,rotateZ]);
}
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderZrotate";}).attr("id",function(){return ID+"_renderZrotate_knob";}).attr("x",132).attr("y",667).attr("width",50).attr("height",50).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").call(drag);
}
//***axes functions***
//***slider function***
function renderSlider (ID) {
var knobThickness = 0.015;
var fontSize = 50;
d3.selectAll("."+ID+"_regionSlider").remove();
sliderTrail(ID);
sliderLeftRect(ID);
sliderRightRect(ID);
silderHighlight(ID);
sliderIndicators(ID);
function sliderTrail (ID) {
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_regionSlider";}).attr("x",0.1*width).attr("y",0.85*height).attr("width",0.8*width).attr("height",0.004*height).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",0.85).delay(0).duration(1000);
}
function sliderLeftRect (ID) {
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobPos = Math.max((0.1-knobThickness/2)*width,Math.min(((0.1+(regions[1]-1)/(fasta_sorted.length-1)*0.8)-1.5*knobThickness)*width,d3.event.x));
d3.select(this).attr("x",knobPos);
regions[0] = ((knobPos/width-(0.1-knobThickness/2))*(fasta_sorted.length-1)/0.8)+1;
d3.select("#"+ID+"_sliderHighlight").attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8)+knobThickness/2)*width}).attr("width",function(){var w = ((regions[1]-regions[0])/(fasta_sorted.length-1)*0.8-knobThickness)*width; return w>=0?w:0;});
d3.select("#"+ID+"_sliderIndicator0").text(Math.round(regions[0])).attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8))*width-2*fontSize;});
args = filterOrdinator(points);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("id",function() {return ID+"_sliderLeftRect";}).attr("class",function(){return ID+"_regionSlider";}).attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8)-knobThickness/2)*width}).attr("y",0.825*height).attr("width",knobThickness*width).attr("height",0.05*height).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",0.85).delay(0).duration(1000);
d3.select("#"+ID+"_sliderLeftRect").call(drag);
}
function sliderRightRect (ID) {
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobPos = Math.max(((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8)+knobThickness/2)*width,Math.min((0.9-knobThickness/2)*width,d3.event.x));
d3.select(this).attr("x",knobPos);
regions[1] = ((knobPos/width-(0.1-knobThickness/2))*(fasta_sorted.length-1)/0.8)+1;
d3.select("#"+ID+"_sliderHighlight").attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8)+knobThickness/2)*width}).attr("width",function(){var w = ((regions[1]-regions[0])/(fasta_sorted.length-1)*0.8-knobThickness)*width; return w>=0?w:0;});
d3.select("#"+ID+"_sliderIndicator1").text(Math.round(regions[1])).attr("x",function(){return ((0.1+(regions[1]-1)/(fasta_sorted.length-1)*0.8))*width+2*fontSize;});
args = filterOrdinator(points);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("id",function() {return ID+"_sliderRightRect";}).attr("class",function(){return ID+"_regionSlider";}).attr("x",function(){return ((0.1+(regions[1]-1)/(fasta_sorted.length-1)*0.8)-knobThickness/2)*width;}).attr("y",0.825*height).attr("width",knobThickness*width).attr("height",0.05*height).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",0.85).delay(0).duration(1000);
d3.select("#"+ID+"_sliderRightRect").call(drag);
}
function silderHighlight (ID) {
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var widthHighlight = +d3.select(this).attr("width");
var min = (0.1+knobThickness/2)*width;
var max = (0.9-knobThickness/2)*width-widthHighlight;
var knobPos = Math.max(min,Math.min(max,d3.event.x));
var newRegions0 = (knobPos/width-0.1-knobThickness/2)/0.8*(fasta_sorted.length-1)+1;
var diff = newRegions0 - regions[0];
var newRegions1 = regions[1]+diff;
regions[0] = newRegions0;
regions[1] = newRegions1;
d3.select(this).attr("x",knobPos);
d3.select("#"+ID+"_sliderLeftRect").attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8)-knobThickness/2)*width});
d3.select("#"+ID+"_sliderRightRect").attr("x",function(){return ((0.1+(regions[1]-1)/(fasta_sorted.length-1)*0.8)-knobThickness/2)*width;});
d3.select("#"+ID+"_sliderIndicator0").text(Math.round(regions[0])).attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8))*width-2*fontSize;});
d3.select("#"+ID+"_sliderIndicator1").text(Math.round(regions[1])).attr("x",function(){return ((0.1+(regions[1]-1)/(fasta_sorted.length-1)*0.8))*width+2*fontSize;});
args = filterOrdinator(points);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("id",function() {return ID+"_sliderHighlight";}).attr("class",function(){return ID+"_regionSlider";}).attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8)+knobThickness/2)*width}).attr("y",0.825*height).attr("width",function(){return ((regions[1]-regions[0])/(fasta_sorted.length-1)*0.8-knobThickness)*width;}).attr("height",0.05*height).attr("fill-opacity",0).attr("fill","DarkSalmon").transition("fadein").attr("fill-opacity",0.50).delay(0).duration(1000);
d3.select("#"+ID+"_sliderHighlight").call(drag);
}
function sliderIndicators (ID) {
d3.select("#"+ID).append("text").text(Math.round(regions[0])).attr("id",function() {return ID+"_sliderIndicator0";}).attr("class",function(){return ID+"_regionSlider";}).attr("x",function(){return ((0.1+(regions[0]-1)/(fasta_sorted.length-1)*0.8))*width-2*fontSize;}).attr("y",0.820*height).attr("font-size",fontSize).attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text(Math.round(regions[1])).attr("id",function() {return ID+"_sliderIndicator1";}).attr("class",function(){return ID+"_regionSlider";}).attr("x",function(){return ((0.1+(regions[1]-1)/(fasta_sorted.length-1)*0.8))*width+2*fontSize;}).attr("y",0.820*height).attr("font-size",fontSize).attr("font-family","sans-serif").attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
}
}
//***slider function***
//***Aminoacid(AA) dial --- if WtOrMt argument is 0 than the wildtype aa dial is placed, else if it is 1 than the mutated ones are placed***
function renderAADials(ID,WtOrMt) {
d3.selectAll("."+ID+"_"+WtOrMt+"_AADials").remove();
var dims = Math.min(width,height);
d3.select("#"+ID).append("text").text(function(){return WtOrMt===0?"from":"to"}).attr("x",function(){return (0.1+WtOrMt*0.47-0.050)*width}).attr("y",function(d,i){return 0.9*height+0.0125*dims+dims/120;}).attr("fill","AntiqueWhite").attr("fill-opacity",0.9).attr("font-size",dims/40).attr("font-family","sans-serif").attr("font-weight",900).style("cursor","default").attr("text-anchor","middle").attr("class",ID+"_"+WtOrMt+"_AADials");
d3.select("#"+ID).selectAll("wildtypeDials")
.data(filterAA[WtOrMt])
.enter()
.append("rect")
.attr("x",function(d,i){return (0.1+WtOrMt*0.47+0.033*(i%10))*width;})
.attr("y",function(d,i){return (0.875+0.033*Math.floor(i/10))*height;})
.attr("width",0.025*dims)
.attr("height",0.025*dims)
.attr("rx",5)
.attr("ry",5)
.attr("fill","Orange")
.attr("stroke","Orange")
.attr("fill-opacity",0)
.attr("stroke-opacity",0)
.attr("stroke-width",10)
.attr("class",ID+"_"+WtOrMt+"_AADials "+ID+"_"+WtOrMt+"_AADialsRects")
.attr("id",function(d,i){return ID+"_"+WtOrMt+"_AADials"+"_"+i;})
.on("mouseover",function(d,i){d3.select(this).attr("stroke-width",20);})
.on("mouseout",function(d,i){d3.select(this).attr("stroke-width",10);})
.on("click",function(d,i){d3.select(this).attr("stroke-width",10).attr("fill",function(){return filterAA[WtOrMt][i][1]==="on"?"DimGray":"Orange";});filterAA[WtOrMt][i][1]=filterAA[WtOrMt][i][1]==="on"?"off":"on";args = filterOrdinator(points);renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein")
.attr("fill-opacity",0.85)
.attr("stroke-opacity",0.9)
.delay(function(d,i){return i*50;})
.duration(function(d,i){return 150;});
d3.select("#"+ID).selectAll("wildtypeDialsTexts")
.data(filterAA[WtOrMt])
.enter()
.append("text")
.text(function(d,i){return d[0];})
.attr("x",function(d,i){return (0.1+WtOrMt*0.47+0.033*(i%10))*width+0.0125*dims;})
.attr("y",function(d,i){return (0.875+0.033*Math.floor(i/10))*height+0.0125*dims+dims/120;})
.attr("fill","AntiqueWhite")
.attr("fill-opacity",0)
.attr("font-size",dims/40)
.attr("font-family","sans-serif")
.attr("font-weight",800)
.style("cursor","default")
.attr("text-anchor","middle")
.attr("class",ID+"_"+WtOrMt+"_AADials")
.on("mouseover",function(d,i){d3.select("#"+ID+"_"+WtOrMt+"_AADials"+"_"+i).attr("stroke-width",20);})
.on("mouseout",function(d,i){d3.select("#"+ID+"_"+WtOrMt+"_AADials"+"_"+i).attr("stroke-width",10);})
.on("click",function(d,i){d3.select("#"+ID+"_"+WtOrMt+"_AADials"+"_"+i).attr("stroke-width",10).attr("fill",function(){return filterAA[WtOrMt][i][1]==="on"?"DimGray":"Orange";});filterAA[WtOrMt][i][1]=filterAA[WtOrMt][i][1]==="on"?"off":"on";args = filterOrdinator(points);renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein")
.attr("fill-opacity",0.9)
.delay(function(d,i){return i*50;})
.duration(function(d,i){return 150;});
}
//***Aminoacid(AA) dial --- if WtOrMt argument is 0 than the wildtype aa dial is placed, else if it is 1 than the mutated ones are placed***
//**AAMassDials--selects all or none. Places 4 buttons based on WtOrMt argument, 2 for each side.
function renderAAmassDials (ID,WtOrMt) {
d3.selectAll("."+ID+"_"+WtOrMt+"_AAmassDials").remove();
var dims = Math.min(width,height);
d3.select("#"+ID).selectAll("massDials")
.data(d3.range(2))
.enter()
.append("rect")
.attr("x",function(d,i){if (WtOrMt===0){return (0.1+WtOrMt*0.47+0.066*((i+20)%10))*width;}else{return (0.1+WtOrMt*0.47+0.066*((i+21)%10))*width;}})
.attr("y",function(d,i){return (0.875+0.033*Math.floor((i+20)/10))*height;})
.attr("width",0.05*dims)
.attr("height",0.025*dims)
.attr("rx",5)
.attr("ry",5)
.attr("fill","Orange")
.attr("stroke","Orange")
.attr("fill-opacity",0)
.attr("stroke-opacity",0)
.attr("stroke-width",10)
.attr("class",ID+"_"+WtOrMt+"_AAmassDials")
.attr("id",function(d,i){return ID+"_"+WtOrMt+"_AAmassDials_"+i;})
.on("mouseover",function(d,i){d3.select(this).attr("stroke-width",20);})
.on("mouseout",function(d,i){d3.select(this).attr("stroke-width",10);})
.on("click",function(d,i){if (i===0){filterAA[WtOrMt].forEach(function(d,i){d[1]="on"});d3.selectAll("."+ID+"_"+WtOrMt+"_AADialsRects").attr("fill","Orange");}else{filterAA[WtOrMt].forEach(function(d,i){d[1]="off"});d3.selectAll("."+ID+"_"+WtOrMt+"_AADialsRects").attr("fill","DimGray");};args = filterOrdinator(points);renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein")
.attr("fill-opacity",0.85)
.attr("stroke-opacity",0.9)
.delay(function(d,i){return (i+20)*50;})
.duration(function(d,i){return 150;});
d3.select("#"+ID).selectAll("massDialsTexts")
.data(d3.range(2))
.enter()
.append("text")
.text(function(d,i){if(i===0){return "All";}else{return "None";}})
.attr("x",function(d,i){if(WtOrMt===0){return (0.1+WtOrMt*0.47+0.066*((i+20)%10))*width+0.0250*dims;}else{return (0.1+WtOrMt*0.47+0.066*((i+21)%10))*width+0.0250*dims;}})
.attr("y",function(d,i){return (0.875+0.033*Math.floor((i+20)/10))*height+0.0125*dims+dims/180;})
.attr("fill","AntiqueWhite")
.attr("fill-opacity",0)
.attr("font-size",dims/60)
.attr("font-family","sans-serif")
.attr("font-weight",500)
.style("cursor","default")
.attr("text-anchor","middle")
.attr("class",ID+"_"+WtOrMt+"_AAmassDials")
.on("mouseover",function(d,i){d3.select("#"+ID+"_"+WtOrMt+"_AAmassDials"+"_"+i).attr("stroke-width",20);})
.on("mouseout",function(d,i){d3.select("#"+ID+"_"+WtOrMt+"_AAmassDials"+"_"+i).attr("stroke-width",10);})
.on("click",function(d,i){if (i===0){filterAA[WtOrMt].forEach(function(d,i){d[1]="on"});d3.selectAll("."+ID+"_"+WtOrMt+"_AADialsRects").attr("fill","Orange");}else{filterAA[WtOrMt].forEach(function(d,i){d[1]="off"});d3.selectAll("."+ID+"_"+WtOrMt+"_AADialsRects").attr("fill","DimGray");};args = filterOrdinator(points);renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein")
.attr("fill-opacity",0.9)
.delay(function(d,i){return i*50;})
.duration(function(d,i){return 150;});
}
//**AAMassDials--selects all or none. Places 4 buttons based on WtOrMt argument, 2 for each side.
//Show Wildtype/Mutated and Show NA
function renderShowModules(ID) {
d3.selectAll("."+ID+"_ShowModulesTexts").remove();
d3.select("#"+ID).append("text").text(function(){return glyphOrigin===1?"Show Wildtype":"Show Mutated"}).attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",function(){return width-350;}).attr("y",400).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.on("click",function(){if(glyphOrigin===1){glyphOrigin=0}else{glyphOrigin=1};d3.select(this).text(function(){return glyphOrigin===1?"Show Wildtype":"Show Mutated"});renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text(function(){return filterNA===1?"Show 'NA' values":"Hide 'NA' values"}).attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",275).attr("y",400).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.on("click",function(){if(filterNA===1){filterNA=0}else{filterNA=1};d3.select(this).text(function(){return filterNA===1?"Show 'NA' values":"Hide 'NA' values"});args = filterOrdinator(points);renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text(function(){return filterSynonymous===1?"Show Synonymous":"Hide Synonymous"}).attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",width/2).attr("y",400).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.on("click",function(){if(filterSynonymous===1){filterSynonymous=0}else{filterSynonymous=1};d3.select(this).text(function(){return filterSynonymous===1?"Show Synonymous":"Hide Synonymous"});args = filterOrdinator(points);renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text(function(){return showLabels===1?"Hide Labels":"Show Labels"}).attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",235).attr("y",500).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.on("click",function(){if(showLabels===1){showLabels=0}else{showLabels=1};d3.select(this).text(function(){return showLabels===1?"Hide Labels":"Show Labels"});renderAxes([currentRotateX,currentRotateY,currentRotateZ],1);})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text("Show Functions").attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",function(){return width-330;}).attr("y",500).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.on("click",function(){var IDfunc= ID+"_func"; d3.select("#"+IDfunc).remove();renderWindow("svg",IDfunc,{"x":+d3.select("#"+ID).attr("x")-1500,"y":+d3.select("#"+ID).attr("y"),"width":1500,"height":2500,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":2500},displayFunctionTable);})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text(function(){for (var i=0,syn=0;i<args.length;i++){if(synOrNonsyn(ids["mut"][args[i][3]])==="Synonymous"){syn++}} return "Syn: "+syn;}).attr("id",function(){return ID+"_synonymousIndicator"}).attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",function(){return width/2-200;}).attr("y",500).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("text").text(function(){for (var i=0,nonSyn=0;i<args.length;i++){if(synOrNonsyn(ids["mut"][args[i][3]])==="Nonsynonymous"){nonSyn++}} return "Nonsyn: "+nonSyn;}).attr("id",function(){return ID+"_nonsynonymousIndicator"}).attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",function(){return width/2+100;}).attr("y",500).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0)
.on("mouseover",function(){d3.select(this).attr("fill","Orange");})
.on("mouseout",function(){d3.select(this).attr("fill","AntiqueWhite");})
.transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_ShowModulesTexts"}).attr("id",ID+"_traceRect").attr("x",width/2-75).attr("y",0.935*height).attr("width",150).attr("height",60).attr("rx",15).attr("ry",15).attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.85).attr("stroke-opacity",9).attr("stroke-width",10);
d3.select("#"+ID).append("text").text("trace").attr("class",function(){return ID+"_ShowModulesTexts"}).attr("x",width/2).attr("y",0.935*height+40).attr("font-size",40).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0.85).style("cursor","default")
.on("mouseover",function(){d3.select("#"+ID+"_traceRect").transition().attr("fill","DarkSalmon").delay(0).duration(500);})
.on("mouseout",function(){d3.select("#"+ID+"_traceRect").transition().attr("fill","Orange").delay(0).duration(500);})
.on("click",function(){if(showTraceLine===1){showTraceLine=0;d3.select("#"+ID+"_traceLine").remove();}else{showTraceLine=1;drawTraceLine(args,[currentRotateX,currentRotateY,currentRotateZ],0);}});
}
//Show Wildtype/Mutated and Show NA
//Zoom Level and Glyph size and the text size
function renderSizeControls (ID) {
renderZoom(ID);
renderTextSize(ID);
renderGlyphSize(ID);
function renderZoom (ID) {
d3.selectAll("."+ID+"_renderZoom").remove();
d3.select("#"+ID).append("text").text("zoom").attr("class",function(){return ID+"_renderZoom";}).attr("x",width-150).attr("y",615).attr("font-size","50px").attr("font-family","sans-serif").attr("font-weight",700).attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderZoom";}).attr("x",width-150).attr("y",685).attr("width",15).attr("height",300).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobPos = Math.max(667,Math.min(667+300,d3.event.y));
d3.select(this).attr("y",knobPos);
var zoomLevel = (knobPos-667)/300*2.5+0.5;
widthScale = zoomLevel*1/3;
heightScale = zoomLevel*1/6;
renderAxes([currentRotateX,currentRotateY,currentRotateZ],1);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderZoom";}).attr("id",function(){return ID+"_renderZoom_knob";}).attr("x",width-168).attr("y",727).attr("width",50).attr("height",50).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").call(drag);
}
function renderTextSize (ID) {
d3.selectAll("."+ID+"_renderTextSize").remove();
d3.select("#"+ID).append("text").text("text-size").attr("class",function(){return ID+"_renderTextSize";}).attr("x",width-150).attr("y",1050).attr("font-size","50px").attr("font-family","sans-serif").attr("font-weight",700).attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderTextSize";}).attr("x",width-150).attr("y",1120).attr("width",15).attr("height",300).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobPos = Math.max(1102,Math.min(1102+300,d3.event.y));
d3.select(this).attr("y",knobPos);
var zoomLevel = (knobPos-1102)/300*2.75+0.25;
fontSize = wTimesH/70000*zoomLevel;
renderAxes([currentRotateX,currentRotateY,currentRotateZ],1);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderTextSize";}).attr("id",function(){return ID+"_renderTextSize_knob";}).attr("x",width-168).attr("y",1184).attr("width",50).attr("height",50).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").call(drag);
}
function renderGlyphSize (ID) {
d3.selectAll("."+ID+"_renderGlyphSize").remove();
d3.select("#"+ID).append("text").text("glyph-size").attr("class",function(){return ID+"_renderGlyphSize";}).attr("x",width-150).attr("y",1515).attr("font-size","50px").attr("font-family","sans-serif").attr("font-weight",700).attr("text-anchor","middle").attr("fill","Orange").attr("fill-opacity",0).transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderGlyphSize";}).attr("x",width-150).attr("y",1585).attr("width",15).attr("height",300).attr("rx",15).attr("ry",15).attr("fill-opacity",0).attr("fill","Orange").transition("fadein").attr("fill-opacity",1).delay(0).duration(1000);
var drag = d3.behavior.drag().origin(function(){var x = +d3.select(this).attr("x"); var y = +d3.select(this).attr("y"); return {"x":x,"y":y};}).on("drag", dragFunc).on("dragstart",function (){d3.event.sourceEvent.stopPropagation();});
function dragFunc() {
var knobPos = Math.max(1567,Math.min(1567+300,d3.event.y));
d3.select(this).attr("y",knobPos);
glyphMultiplier = (knobPos-1567)/300*2.75+0.25;
renderAxes([currentRotateX,currentRotateY,currentRotateZ],1);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
d3.select("#"+ID).append("rect").attr("class",function(){return ID+"_renderTextSize";}).attr("id",function(){return ID+"_renderGlyphSize_knob";}).attr("x",width-168).attr("y",1649).attr("width",50).attr("height",50).attr("rx",15).attr("ry",15).attr("fill-opacity",1).attr("fill","Orange").call(drag);
}
}
//Zoom Level and Glyph size and the text size
}
function filterOrdinator (input) {
input = input.filter(function(d,i){return pointLocations[d[3]]>=Math.round(regions[0])&&pointLocations[d[3]]<=Math.round(regions[1])});
input = input.filter(function(d,i){if(filterSynonymous===1){return wildtypeAndMutated[d[3]][0]!==wildtypeAndMutated[d[3]][1]}else{return true;}});
input = input.filter(function(d,i){return filterAA[0].some(function(u,w){return u[0]===wildtypeAndMutated[d[3]][0]&&u[1]==="on"})&&filterAA[1].some(function(u,w){return u[0]===wildtypeAndMutated[d[3]][1]&&u[1]==="on"})});
input = input.filter(function(d,i){if(filterNA===1){return d.map(function(u,w){return u*[1,-1,1,1][w]}).every(function(u,w){return u>=0})}else{return true;}})
//update syn/Nonsyn indicators
d3.select("#"+ID+"_synonymousIndicator").text(function(){for (var i=0,syn=0;i<input.length;i++){if(synOrNonsyn(ids["mut"][input[i][3]])==="Synonymous"){syn++}} return "Syn: "+syn;});
d3.select("#"+ID+"_nonsynonymousIndicator").text(function(){for (var i=0,nonSyn=0;i<input.length;i++){if(synOrNonsyn(ids["mut"][input[i][3]])==="Nonsynonymous"){nonSyn++}} return "Nonsyn: "+nonSyn;});
//update syn/Nonsyn indicators
return input;
}
function drawTraceLine (args,angleArray,refresh) {
d3.select("#"+ID+"_traceLine").remove();
var points = [];
var length = args.length;
for (var i=0;i<length;i++) {
points[i] = ordinatorRotate(args[i],angleArray);
}
points.sort(function(a,b){return pointLocations[a[3]]-pointLocations[b[3]]});
var lineArray = [];
for (var i=0;i<length;i++) {
var mapped = ordinatorMap2D(points[i]);
lineArray[i]=[];
lineArray[i][0] = (mapped[0]*widthScale+widthTranslate)*width;
lineArray[i][1] = (mapped[1]*heightScale+heightTranslate)*height;
}
var line = d3.svg.line().interpolate("cardinal");
d3.select("#"+ID).append("path")
.attr("d",function(){return refresh===1?line(lineArray):line([lineArray[0]]);})
.attr("fill","none")
.attr("stroke-width",5)
.attr("stroke","DarkSalmon")
.attr("stroke-opacity",0.6)
.attr("id",ID+"_traceLine")
.style("marker-end","url(#markerTriangle)");
if (refresh !==1){
d3.select("#"+ID+"_traceLine").transition("extendTrace").attrTween("d",function(){return trace(this,lineArray,Math.max(100,Math.min(length,300)),0)}).delay(0).duration(10000);
}
}
function registerLinks (point) {
d3.selectAll(".ordinator_"+ID+"_registerLinkBoxes").remove();
clearInterval(intervalButtons);
clearInterval(intervalHighlight);
d3.select("#"+ID).append("rect").attr("id","ordinator_"+ID+"_registerLinkRect1").attr("class","ordinator_"+ID+"_registerLinkBoxes").attr("width",240).attr("height",80).attr("rx",15).attr("ry",15).attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.85);
d3.select("#"+ID).append("rect").attr("id","ordinator_"+ID+"_registerLinkRect2").attr("class","ordinator_"+ID+"_registerLinkBoxes").attr("width",240).attr("height",80).attr("rx",15).attr("ry",15).attr("fill","Orange").attr("stroke","Orange").attr("fill-opacity",0.85);
d3.select("#"+ID).append("text").text(function(){if (linkingStatus===0){return "link"}else{return "end"}}).attr("id","ordinator_"+ID+"_registerLinkText1").attr("class","ordinator_"+ID+"_registerLinkBoxes").attr("dx",120).attr("dy",50).attr("font-size",60).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0.85).style("cursor","default")
.on("mouseover",function(){d3.select("#ordinator_"+ID+"_registerLinkRect1").attr("fill","DarkSalmon")})
.on("mouseout",function(){d3.select("#ordinator_"+ID+"_registerLinkRect1").attr("fill","Orange")})
.on("click",function(){
if(d3.select(this).text()==="link") {
linkingStatus=1;
links[linkCounter] =[];
links[linkCounter].push(point[3]);
linksColors.push("rgb(255,215,0)");
linksAlphas.push(0.5);
clearInterval(intervalButtons);
intervalHighlight = setInterval(function(){animateDashArray("#ordinatorPoint_"+ID+"_"+point[3]);},1000);
d3.selectAll(".ordinator_"+ID+"_registerLinkBoxes").remove();
} else {
linkingStatus=0;
if (links[linkCounter][links[linkCounter].length-1] !== point[3]){
links[linkCounter].push(point[3]);
}
linkCounter++;
clearInterval(intervalButtons);
clearInterval(intervalHighlight);
d3.selectAll(".ordinator_"+ID+"_registerLinkBoxes").remove();
//links[linkCounter].forEach(function(d,i){d3.select("#ordinatorPoint_"+ID+"_"+d).attr("stroke-width",2);});
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
});
d3.select("#"+ID).append("text").text("cancel").attr("id","ordinator_"+ID+"_registerLinkText2").attr("class","ordinator_"+ID+"_registerLinkBoxes").attr("dx",120).attr("dy",50).attr("font-size",60).attr("font-family","sans-serif").attr("font-weight",600).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0.85).style("cursor","default")
.on("mouseover",function(){d3.select("#ordinator_"+ID+"_registerLinkRect2").attr("fill","DarkSalmon")})
.on("mouseout",function(){d3.select("#ordinator_"+ID+"_registerLinkRect2").attr("fill","Orange")})
.on("click",function(){
if(linkingStatus===1) {
linkingStatus=0;
links.pop();
linksColors.pop();
linksAlphas.pop();
clearInterval(intervalButtons);
clearInterval(intervalHighlight);
d3.selectAll(".ordinator_"+ID+"_registerLinkBoxes").remove();
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
} else {
clearInterval(intervalButtons);
clearInterval(intervalHighlight);
d3.selectAll(".ordinator_"+ID+"_registerLinkBoxes").remove();
}
});
intervalButtons = setInterval(function(){updatePos("#ordinator_"+ID+"_registerLinkRect1","#ordinator_"+ID+"_registerLinkRect2");updatePos("#ordinator_"+ID+"_registerLinkText1","#ordinator_"+ID+"_registerLinkText2");},100);
if(linkingStatus===1) {
if (links[linkCounter][links[linkCounter].length-1] !== point[3]){
links[linkCounter].push(point[3]);
}
intervalHighlight = setInterval(function(){links[linkCounter].forEach(function(d,i){animateDashArray("#ordinatorPoint_"+ID+"_"+d);})},1000);
}
function animateDashArray(element) {
if(d3.select("#"+ID).node()) {
d3.select(element).attr("stroke-width",25).attr("stroke","Orange").attr("stroke-dasharray","20 5");
d3.select(element).transition("highlight").ease("linear").attrTween("stroke-dashoffset",function(){var interpolator = d3.interpolate(0,-25);return function(t){return interpolator(t);}}).delay(0).duration(1000);
} else {
clearInterval(intervalHighlight);
}
}
function updatePos (element1,element2) {
if(d3.select("#"+ID).node()) {
var original = points[point[3]];
original = ordinatorRotate(original,[currentRotateX,currentRotateY,currentRotateZ]);
var mapped = ordinatorMap2D(original);
var x = mapped[0]*widthScale+widthTranslate;
var y = mapped[1]*heightScale+heightTranslate;
x = x>1/2?x-0.1:x+0.1;
y = y>1/2?y-0.1:y+0.1;
d3.select(element1).attr("x",(x-0.1)*width).attr("y",y*height);
d3.select(element2).attr("x",(x+0.1)*width).attr("y",y*height);
} else {
clearInterval(intervalButtons);
}
}
}
//below function is called by renderGlyphs
function renderPseudoPoly (angleArray) {
var line = d3.svg.line();
var length = links.length;
d3.selectAll("."+ID+"_pseudoPolys").remove();
d3.selectAll("."+"ordinator_"+ID+"_colorPicker").remove();
var pointArrays = [];//[[[points],indexAbsolute,indexRender],..]
var avgZ = [];//[Z,..] default index ordered
for (var i = 0;i<length;i++) {
var currentPointArray = indexArrayToPointArray(links[i],angleArray);
var currentAbsoluteIndex = i;
var currentRenderingIndex = avgZ[i];
pointArrays.push([currentPointArray,currentAbsoluteIndex,currentRenderingIndex]);
}
pointArrays.sort(function(a,b){return a[2]-b[2]});
for (var i = 0;i<length;i++) {
renderSegment(pointArrays[i][0],pointArrays[i][1]);
}
function indexArrayToPointArray(array,angleArray) {
var result = [];
var length = array.length;
var totalZ = 0;
for (var i=0;i<length;i++) {
var original = ordinatorRotate(points[array[i]],angleArray);
var mapped = ordinatorMap2D(original);
var x = (mapped[0]*widthScale+widthTranslate)*width;
var y = (mapped[1]*heightScale+heightTranslate)*height;
totalZ += original[2];
result.push([x,y]);
}
totalZ = totalZ/length;
avgZ.push(totalZ);
return result;
}
function renderSegment (lineArray,index) {
//d3.select("#"+ID+"_pseudoPoly_"+index).remove();
//var line = d3.svg.line();
d3.select("#"+ID).append("path")
.attr("d",function(){return line(lineArray)+" Z";})
.attr("fill",linksColors[index])
.attr("fill-opacity",linksAlphas[index])
.attr("stroke-width",15)
.attr("stroke",linksColors[index])
.attr("stroke-opacity",0.6)
.attr("stroke-linejoin","round")
.attr("stroke-linecap","round")
.attr("id",ID+"_pseudoPoly_"+index)
.attr("class",ID+"_pseudoPolys")
.on("click",function(){
renderColorPicker(lineArray,index);
});
}
function renderColorPicker (lineArray,index) {
d3.selectAll("."+"ordinator_"+ID+"_colorPicker").remove();
var midPoint = [];
var length = lineArray.length;
var xTotal =0;
var yTotal =0;
for (var i =0;i<length;i++) {
xTotal += lineArray[i][0];
yTotal += lineArray[i][1];
}
midPoint.push(xTotal/length);
midPoint.push(yTotal/length);
var rgb = [0,0,0];
var alpha = 0.5;
d3.select("#"+ID).append("rect").attr("id","ordinator_"+ID+"_colorPickerRemove").attr("class","ordinator_"+ID+"_colorPicker").attr("x",function(d,i){return midPoint[0];}).attr("y",function(d,i){return midPoint[1]-80;}).attr("width",240).attr("height",40).attr("fill","Black").attr("stroke","Black").attr("stroke-width",2).attr("fill-opacity",0.85);
d3.select("#"+ID).append("text").text("REMOVE").attr("class","ordinator_"+ID+"_colorPicker").attr("x",function(d,i){return midPoint[0]+120;}).attr("y",function(d,i){return midPoint[1]-50;}).attr("font-size",30).attr("font-family","sans-serif").attr("font-weight",800).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0.85).style("cursor","default")
.on("mouseover",function(){d3.select("#ordinator_"+ID+"_colorPickerRemove").attr("stroke-width",5).attr("stroke","Orange");})
.on("mouseout",function(){d3.select("#ordinator_"+ID+"_colorPickerRemove").attr("stroke-width",2).attr("stroke","Black");})
.on("click",function(){var linksNew =[];var linksColorsNew = []; var linksAlphasNew = []; for(var i=0;i<links.length;i++){if(i !== index){linksNew.push(links[i]);linksColorsNew.push(linksColors[i]);linksAlphasNew.push(linksAlphas[i])}}; links = linksNew; linksColors = linksColorsNew; linksAlphas = linksAlphasNew; d3.select("#"+ID+"_pseudoPoly_"+index).remove();d3.selectAll("."+"ordinator_"+ID+"_colorPicker").remove();linkCounter--;});
d3.select("#"+ID).append("rect").attr("id","ordinator_"+ID+"_colorPickerApply").attr("class","ordinator_"+ID+"_colorPicker").attr("x",function(d,i){return midPoint[0];}).attr("y",function(d,i){return midPoint[1]-40;}).attr("width",240).attr("height",40).attr("fill",function(){return "rgb("+rgb+")";}).attr("stroke","Black").attr("stroke-width",2).attr("fill-opacity",0.85);
d3.select("#"+ID).append("text").text("APPLY").attr("class","ordinator_"+ID+"_colorPicker").attr("x",function(d,i){return midPoint[0]+120;}).attr("y",function(d,i){return midPoint[1]-10;}).attr("font-size",30).attr("font-family","sans-serif").attr("font-weight",800).attr("text-anchor","middle").attr("fill","AntiqueWhite").attr("fill-opacity",0.85).style("cursor","default")
.on("mouseover",function(){d3.select("#ordinator_"+ID+"_colorPickerApply").attr("stroke-width",5).attr("stroke","Orange");})
.on("mouseout",function(){d3.select("#ordinator_"+ID+"_colorPickerApply").attr("stroke-width",2).attr("stroke","Black");})
.on("click",function(){linksColors[index]="rgb("+rgb+")";linksAlphas[index]= alpha; d3.select("#"+ID+"_pseudoPoly_"+index).transition("changePseudoPolyColor").attr("fill",linksColors[index]).attr("stroke",linksColors[index]).attr("fill-opacity",linksAlphas[index]).delay(0).duration(500);d3.selectAll("."+"ordinator_"+ID+"_colorPicker").remove();});
d3.select("#"+ID).selectAll("ordinatorColorPicker")
.data(d3.range(24))
.enter()
.append("rect")
.attr("x",function(d,i){return midPoint[0]+(i%6)*40})
.attr("y",function(d,i){return midPoint[1]+Math.floor(i/6)*40})
.attr("width",0)
.attr("height",40)
.attr("fill",function(d,i){if(i<6){return "rgb("+(40+(i%6)*40)+",0,0)"}else if(i<12){return "rgb(0,"+(40+(i%6)*40)+",0)"}else if(i<18){return "rgb(0,0,"+(40+(i%6)*40)+")"}else{return "Orange"}})
.attr("fill-opacity",function(d,i){if(i<18){return 0.8}else{return 0.2+(i%6)*0.15}})
.attr("stroke","Black")
.attr("stroke-width",2)
.attr("class","ordinator_"+ID+"_colorPicker")
.on("mouseover",function(){d3.select(this).attr("stroke-width",15).attr("stroke","Orange");})
.on("mouseout",function(){d3.select(this).attr("stroke-width",2).attr("stroke","Black");})
.on("click",function(d,i){if(i<6){rgb[0]=(40+(i%6)*40);d3.select("#ordinator_"+ID+"_colorPickerApply").transition().attr("fill",function(){return "rgb("+rgb+")";}).delay(0).duration(500);}else if(i<12){rgb[1]=(40+(i%6)*40);d3.select("#ordinator_"+ID+"_colorPickerApply").transition().attr("fill",function(){return "rgb("+rgb+")";}).delay(0).duration(500);}else if(i<18){rgb[2]=(40+(i%6)*40);d3.select("#ordinator_"+ID+"_colorPickerApply").transition().attr("fill",function(){return "rgb("+rgb+")";}).delay(0).duration(500);}else{d3.select("#ordinator_"+ID+"_colorPickerApply").transition().attr("fill-opacity",function(){return 0.2+(i%6)*0.15;}).delay(0).duration(500); alpha = 0.2+(i%6)*0.15;}})
.transition("pop")
.ease("elastic")
.attr("width",40)
.delay(function(d,i){return i*20})
.duration(250);
}
}
//Render Function Table
var defaultFunctions = ["polyphen2","sift","position"];
function displayFunctionTable (ID) {
//d3.selectAll("."+ID+"_rects").remove();
//d3.selectAll("."+ID+"_texts").remove();
d3.select("#"+ID+"enlarge").remove();
d3.select("#"+ID+"magnify").remove();
d3.select("#"+ID+"minify").remove();
var options = ["X","Y","Z",
"polyphen2",
"sift",
"position",
"chemicalType",
"altType",
"AAtype",
"altAAtype",
"hydro",
"altHydro",
"avgPrediction",
"aaChange",
"domain",
"customdb",
"MAF",
"conservation",
"aggregateFeature",
"hist1",
"hist2",
"hist3"];
var svgWidth = +d3.select("#"+ID).attr("width");
var svgHeight = +d3.select("#"+ID).attr("height");
var rectWidth = 0.9*svgWidth/4;
var rectHeight = 0.8*svgHeight/(options.length-2);
var horPadding = 0.05*svgWidth;
var verPadding = 0.1*svgHeight;
//var defaultFunctions = ["polyphen2","sift","position"];
d3.select("#"+ID).selectAll("Ordinator_funcRects")
.data(d3.range((options.length-2)*4))
.enter()
.append("rect")
.attr("x",function(d,i){return horPadding+(i%4)*rectWidth;})
.attr("y",function(d,i){return verPadding+Math.floor(i/4)*rectHeight;})
.attr("width",0)
.attr("height",0)
.attr("fill",function(d,i){if(i<4 || i%4 === 0){return "Orange"}else if (options[Math.floor(i/4)+2] === defaultFunctions[(i%4)-1]){return "Green";}else{return "DimGray"}})
.attr("fill-opacity",function(d,i){return Math.sign(i)*0.5;})
.attr("stroke",function(d,i){if(i<4 || i%4 === 0){return "Orange"}else{return "DimGray"}})
.attr("stroke-opacity",function(d,i){return Math.sign(i)*0.75;})
.attr("stroke-width",4)
.attr("class",function(d,i){return ID+"_rects";})
.on("mouseover",function(d,i){if(i>4 && i%4 !== 0){d3.select(this).attr("stroke-width",20);}})
.on("mouseout",function(d,i){if(i>4 && i%4 !== 0){d3.select(this).transition().attr("stroke-width",4).delay(0).duration(300);}})
.on("click",function(d,i){
if(i>4 && i%4 !==0) {
defaultFunctions[(i%4)-1] = options[Math.floor(i/4)+2];
//console.log(defaultFunctions);
d3.selectAll("."+ID+"_rects").attr("fill",function(d,i){if(i<4 || i%4 === 0){return "Orange"}else if (options[Math.floor(i/4)+2] === defaultFunctions[(i%4)-1]){return "Green";}else{return "DimGray"}});
updatePoints(defaultFunctions);
}
})
.transition("pop")
.ease("elastic")
.attr("width",rectWidth)
.attr("height",rectHeight)
.delay(function(d,i){return i*10})
.duration(500);
d3.select("#"+ID).selectAll("Ordinator_funcTexts")
.data(d3.range(options.length))
.enter()
.append("text")
.text(function(d,i){return options[i];})
.attr("x",function(d,i){if(i<3){return horPadding+((i+1)%4)*rectWidth;}else{return horPadding;}})
.attr("dx",rectWidth/2)
.attr("y",function(d,i){if(i<3){return verPadding;}else{return verPadding+Math.floor(i-2)*rectHeight;}})
.attr("dy",rectHeight*2/3)
.attr("fill","Black")
.attr("fill-opacity",0)
.attr("stroke","DimGray")
.attr("stroke-opacity",0)
.attr("stroke-width",0)
.attr("font-size",function(d,i){if(i<3){return 80;}else{return 50;}})
.attr("font-family","sans-serif")
.attr("font-weight",function(d,i){if(i<3){return 800;}else{return 400;}})
.attr("text-anchor","middle")
.attr("class",function(d,i){return ID+"_texts";})
.transition("fadein")
.attr("fill-opacity",0.9)
.delay(function(d,i){return i*10})
.duration(500);
//prevent accidental text selection
d3.selectAll("."+ID+"_texts").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
}
//Render Function Table
//Update Points
function updatePoints (functionArray) {
args = ordinatorFetchData(functionArray[0],functionArray[1],functionArray[2]);
labels = args.labels;
labelNames = args.labelNames;
points = args.points;
pointsRef = [];
points.forEach(function(d,i){pointsRef[i]= [d[0],-d[1],d[2]];});
args = filterOrdinator(points);
renderAxes([currentRotateX,currentRotateY,currentRotateZ],1);
renderGlyphs(args,[currentRotateX,currentRotateY,currentRotateZ]);
}
//Update Points
}
//Add the logo and the initiate Indoril/Ordinator
d3.select("#master").append("path").attr("id","indorilLogoPath").attr("class","indorilLogo").attr("d","M -100,5800").attr("stroke","Orange").attr("stroke-width",300).attr("fill","transparent").attr("stroke-dasharray","20 10");
d3.select("#master").append("circle").attr("id","indorilLogoCircle").attr("class","indorilLogo").attr("r",300).attr("cx",-100).attr("cy",5800).attr("fill","AntiqueWhite").attr("fill-opacity",1);
d3.select("#master").append("svg:image").attr("xlink:href","data:image/png;base64,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")
.attr("id","indorilLogoImage").attr("class","indorilLogo").attr("title","indoril").attr("alt","indorilLogo").attr("x",-400).attr("y",5500).attr("width",600).attr("height",600).style("opacity",1)
.on("mouseover",function(){
d3.select("#indorilLogoCircle").transition().attr("fill","Orange").delay(0).duration(1000);
d3.select("#indorilLogoPath").transition().ease("linear").attrTween("d",function(){return trace(this,(function(){var result = [];for(var i=0,angle=0,radius=50;i<23;i++){var x = -100+radius*Math.sin(angle);var y = 5800-radius*Math.cos(angle);angle += Math.PI/10;radius+=10;result.push([x,y]);}return result;})(),10,1);}).delay(0).duration(750);
})
.on("mouseout",function(){
d3.select("#indorilLogoCircle").transition().attr("fill","AntiqueWhite").delay(0).duration(1000);
d3.select("#indorilLogoPath").transition().ease("linear").attrTween("d",function(){ var length = this.getTotalLength(); var terminal = this.getPointAtLength(length); var rCurrent = Math.floor(Math.sqrt(Math.pow(terminal.x+100,2)+Math.pow(terminal.y-5800,2))/10)*10; var iCurrent = (rCurrent-50)/10; var angleCurrent = iCurrent*Math.PI/10; return traceBack(this,(function(){var result = [];for(var i=0,angle=0,radius=50;i<=iCurrent;i++){var x = -100+radius*Math.sin(angle);var y = 5800-radius*Math.cos(angle);angle += Math.PI/10;radius +=10;result.push([x,y]);};return result;})(),10,1);}).delay(0).duration(750);
})
.on("click",function(){
d3.select("#Ordinator").remove();
//renderWindow("svg","Ordinator",sampleLoc,ordinator,[[1,0,0,0],[0,-1,0,1],[0,0,1,2],[0.5,0.5,0.5,3],[0.5,-1,0.75,4],[0.75,0.2,0.3,5]]);
renderWindow("svg","Ordinator",{"x":1500,"y":1500,"width":1500,"height":2500,"rx":100,"ry":100,"iconPadding":100,"iconSize":100,"minWidth":1500,"minHeight":2500,"maxWidth":5000,"maxHeight":5000},ordinator,ordinatorFetchData("polyphen2","sift","position"));
});
//Add the logo and the initiate Indoril/Ordinator
<!--Ordinator-->
<!--Global Trace Function for paths-->
//Mode 0 is where the resolution corresponds to the number of equal segments of a path. Mode 1 is unit based. In mode 1, resolution of 10 will mean the path will be divided into segments of length 10.
//If your points are equally distributed, than go for mode 0 (less work), otherwise go for mode 1 which will be more accurate (more work).
function trace (path,pointArray,resolution,mode) {
var line = d3.svg.line().interpolate("cardinal");
var endPath = path.cloneNode();
var endPathString = line(pointArray);
endPath.setAttribute("d",endPathString);
var lengthOfString = endPath.getTotalLength();
var sampleDistance = mode===0?lengthOfString/resolution:resolution;
var loopCap = mode===0?resolution:lengthOfString/resolution;
var sampledPoints = [];
for (i=0;i<=loopCap;i++) {
var u = endPath.getPointAtLength(i*sampleDistance);
sampledPoints[i] = [u.x,u.y];
}
return function(t) {
return t<1?line(sampledPoints.slice(0,Math.max(1,Math.floor(t*loopCap)))):line(pointArray)
}
}
function traceBack (path,pointArray,resolution,mode) {
var line = d3.svg.line().interpolate("cardinal");
var endPath = path.cloneNode();
var endPathString = line(pointArray);
endPath.setAttribute("d",endPathString);
var lengthOfString = endPath.getTotalLength();
var sampleDistance = mode===0?lengthOfString/resolution:resolution;
var loopCap = mode===0?resolution:lengthOfString/resolution;
var sampledPoints = [];
for (i=0;i<=loopCap;i++) {
var u = endPath.getPointAtLength(i*sampleDistance);
sampledPoints[i] = [u.x,u.y];
}
return function(t) {
return t<1?line(sampledPoints.slice(0,Math.max(1,Math.floor((1-t)*loopCap)))):line([pointArray[0]])
}
}
<!--Global Trace Function for paths-->
//***Subs***
//Keep unintended text selection issue minimal by disabling selection on majority of text. My understanding is that some text selection is necessary because I am using html5's native eventlistener to translate an svg that is embedded in an another svg. Silencing listeners on the parent svg also silences listeners on the child in this case. I could not find any other solution than selecting a bit of text by Ctrl+A OR double-clicking on the GraphSvg. After this step everything works OK.
//The two elements that are OK to text select are the Graph and the tabs that open when "length: XY aa" is clicked.
d3.select("#master").selectAll(".mut").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
d3.select("#master").selectAll(".sequence").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
d3.select("#master").selectAll(".connector").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
d3.select("#ideograms").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
d3.select("#annotation").selectAll("*").style("user-select","none").style("-moz-user-select","none").style("-webkit-user-select","none").style("-ms-user-select","none");
//Keep text selection process minimal by disabling selection on majority of above text.
//notify that I have been going down the well with someone else's rope..Well ok, perhaps I didn't have one of my own but that still doesn't change the fact.
//alert("With the recent update of chrome there has been a performance issue.\nBefore you begin anything on the page, click on the 'All' above 'Font-Size:1.0x'.\nA dropdown menu will appear.\nRandomly click on the few of the choices.\nThen click back on the 'All' to close dropdown menu.\nThe issue will be resolved.\nYou can watch a demonstration at http://i-pv.org/gifs/chromeGood.gif\nThank you for your understanding,\n\nIbrahim Tanyalcin");
//notify that I have been going down the well with someone else's rope..Well ok, perhaps I didn't have one of my own but that still doesn't change the fact.
<!--Copyright Ibrahim Tanyalcin 2012-2016, All Rights Reserved.--!>
</script>
</body>
</html>