UNPKG

fhirtypes

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import { IBackboneElement, IElement } from '../base'; import { ICodeableConcept, IReference } from '../datatypes'; import { OrientationTypeType, StrandTypeType } from '../types'; /** * @name IMolecularSequenceReferenceSeq * @description Raw data describing a biological sequence. * @see <a href="https://hl7.org/fhir/R4/molecularsequence-definitions.html#MolecularSequence.referenceSeq">IMolecularSequenceReferenceSeq</a> * @version R4 * @extends {IBackboneElement} * @author Claudia Alarcón Lazo */ export interface IMolecularSequenceReferenceSeq extends IBackboneElement { /** * @description Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication ([SO:0000340](http://www.sequenceontology.org/browser/current_svn/term/SO:0000340)). */ chromosome?: ICodeableConcept; /** * @description The Genome Build used for reference, following GRCh build versions e.g. \u0027GRCh 37\u0027. Version number must be included if a versioned release of a primary build was used. */ genomeBuild?: string; /** * @description Extensions for genomeBuild */ _genomeBuild?: IElement; /** * @description A relative reference to a DNA strand based on gene orientation. The strand that contains the open reading frame of the gene is the \"sense\" strand, and the opposite complementary strand is the \"antisense\" strand. * @description sense | antisense * @see <a href="https://hl7.org/fhir/R4/valueset-orientation-type.html">OrientationType</a> */ orientation?: OrientationTypeType; /** * @description Extensions for orientation */ _orientation?: IElement; /** * @description Reference identifier of reference sequence submitted to NCBI. It must match the type in the MolecularSequence.type field. For example, the prefix, “NG_” identifies reference sequence for genes, “NM_” for messenger RNA transcripts, and “NP_” for amino acid sequences. */ referenceSeqId?: ICodeableConcept; /** * @description A pointer to another MolecularSequence entity as reference sequence. */ referenceSeqPointer?: IReference; /** * @description A string like \"ACGT\". */ referenceSeqString?: string; /** * @description Extensions for referenceSeqString */ _referenceSeqString?: IElement; /** * @description An absolute reference to a strand. The Watson strand is the strand whose 5\u0027-end is on the short arm of the chromosome, and the Crick strand as the one whose 5\u0027-end is on the long arm. */ strand?: StrandTypeType; /** * @description Extensions for strand */ _strand?: IElement; /** * @description Start position of the window on the reference sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive. */ windowStart?: number; /** * @description Extensions for windowStart */ _windowStart?: IElement; /** * @description End position of the window on the reference sequence. If the coordinate system is 0-based then end is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position. */ windowEnd?: number; /** * @description Extensions for windowEnd */ _windowEnd?: IElement; }