com.caffeine
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Caffeine package is a collection of utility methods, design patterns, and extensions for creating, previewing, and distributing interactive courses within Unity.
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{
"Name": "Propofol",
"MolarMass": {
"ScalarMassPerAmount": {
"Value": 178.27,
"Unit": "g/mol"
}
},
"State": "Liquid",
"Clearance": {
"SystemicClearance": {
"FractionExcretedInFeces": {
"Scalar0To1": {
"Value": 0.02
}
},
"FractionUnboundInPlasma": {
"Scalar0To1": {
"Value": 0.03
}
},
"IntrinsicClearance": {
"ScalarVolumePerTimeMass": {
"Value": 1.44,
"Unit": "mL/min kg"
}
},
"RenalClearance": {
"ScalarVolumePerTimeMass": {
"Value": 1.3,
"Unit": "mL/min kg"
}
},
"SystemicClearance": {
"ScalarVolumePerTimeMass": {
"Value": 3.0,
"Unit": "mL/min kg"
}
}
},
"RenalClearance": {
"Clearance": {
"ScalarVolumePerTimeMass": {
"Value": 1.3,
"Unit": "mL/min kg"
}
}
}
},
"Pharmacokinetics": {
"Physicochemicals": {
"AcidDissociationConstant": {
"Value": 11.1
},
"BindingProtein": "Albumin",
"BloodPlasmaRatio": {
"Value": 0.03
},
"FractionUnboundInPlasma": {
"Scalar0To1": {
"Value": 0.03
}
},
"IonicState": "Acid",
"LogP": {
"Value": 3.79
}
}
},
"Pharmacodynamics": {
"Bronchodilation": {
"ScalarNegative1To1": {
}
},
"DiastolicPressureModifier": {
"ScalarNegative1To1": {
"Value": -0.35
}
},
"EC50": {
"ScalarMassPerVolume": {
"Value": 0.7649,
"Unit": "ug/mL"
}
},
"EMaxShapeParameter": {
"Value": 1.0
},
"HeartRateModifier": {
"ScalarNegative1To1": {
"Value": -0.2
}
},
"NeuromuscularBlock": {
"ScalarNegative1To1": {
"Value": -0.2
}
},
"PupillaryResponse": {
"ReactivityModifier": {
"ScalarNegative1To1": {
"Value": 0.5
}
},
"SizeModifier": {
"ScalarNegative1To1": {
}
}
},
"RespirationRateModifier": {
"ScalarNegative1To1": {
"Value": 0.15
}
},
"Sedation": {
"ScalarNegative1To1": {
"Value": 1.0
}
},
"SystolicPressureModifier": {
"ScalarNegative1To1": {
"Value": -0.35
}
},
"TidalVolumeModifier": {
"ScalarNegative1To1": {
"Value": -0.1
}
},
"TubularPermeabilityModifier": {
"ScalarNegative1To1": {
}
}
}
}