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t.step()>50?t.padding(.5):e.length<=4?t.padding(.4):e.length<=6?t.padding(.3):e.length<=10?t.padding(.2):t.padding(.1)}function Y(e,t,n){var r=t.step();if(!(t.step()<=50)){for(var i=[],o=100;o--;)i.push((Math.random()-.5)*r*.5);var a=["".concat(e,"Base"),"".concat(e,"Tip"),i.length],s=a[0],l=a[1],c=a[2],h=0;!function e(t){if(t[s]=(0,u.k9)(t.n).shell[l],t[l]+=i[h++],h>=c&&(h=0),t.n.hasChildren){var n,r=G(t.n.children);try{for(r.s();!(n=r.n()).done;)e(n.value.shell)}catch(e){r.e(e)}finally{r.f()}}}(n[0])}}function X(e,t){var n=0;if(t.length<e.tipLabelBreakL1){var r=e.tipLabelFontSizeL1;t.length<e.tipLabelBreakL2&&(r=e.tipLabelFontSizeL2),t.length<e.tipLabelBreakL3&&(r=e.tipLabelFontSizeL3),t.forEach(function(e){n<e.n.name.length&&(n=.65*e.n.name.length*r)})}return n}function J(e){return e.tipCount+.15*(e.fullTipCount-e.tipCount)}var Z=n(58026),ee=function(e,t,n){var r=this;this.grid=!1,this.attributes=["r","cx","cy","id","class","d"],this.params={regressionStroke:l.KD,regressionWidth:6,majorGridStroke:"#DDD",majorGridWidth:2,minorGridStroke:"#EEE",minorGridWidth:1,tickLabelSize:12,tickLabelFill:l.KD,minorTicks:4,orientation:[1,1],showGrid:!0,showStreamTrees:!1,fillSelected:"#A73",radiusSelected:5,branchStroke:"#AAA",branchStrokeWidth:2,tipStroke:"#AAA",tipFill:"#CCC",tipStrokeWidth:1,tipRadius:4,fontFamily:l.sf,branchLabelKey:!1,branchLabelFont:l.sf,branchLabelFill:"#777",branchLabelFontWeight:500,branchLabelPadX:8,branchLabelPadY:5,tipLabels:!0,tipLabelFont:l.sf,tipLabelFill:"#555",tipLabelPadX:8,tipLabelPadY:2,mapToScreenDebounceTime:500,tipLabelFontSizeL1:8,tipLabelFontSizeL2:10,tipLabelFontSizeL3:12,tipLabelBreakL1:75,tipLabelBreakL2:50,tipLabelBreakL3:25},this.groups={},this.id=t,this.nodes=e.map(function(e){var t={that:r,n:e,x:0,y:0,inView:void 0===e.inView||e.inView};return e.shell=t,t}),this.zoomNode=this.nodes[n],this.strainToNode={},this.nodes.forEach(function(e){r.strainToNode[e.n.name]=e})};ee.prototype.change=function(e){var t,n,r=e.changeColorBy,i=void 0!==r&&r,o=e.changeVisibility,a=void 0!==o&&o,s=e.changeTipRadii,l=void 0!==s&&s,c=e.changeBranchThickness,h=void 0!==c&&c,p=e.showConfidences,d=void 0!==p&&p,f=e.removeConfidences,m=void 0!==f&&f,y=e.zoomIntoClade,g=void 0!==y&&y,v=e.svgHasChangedDimensions,b=void 0!==v&&v,w=e.animationInProgress,S=void 0!==w&&w,E=e.changeNodeOrder,x=void 0!==E&&E,k=e.focusChange,C=void 0!==k&&k,T=e.newDistance,O=void 0===T?void 0:T,_=e.newLayout,j=void 0===_?void 0:_,A=e.updateLayout,L=void 0===A?void 0:A,P=e.newBranchLabellingKey,I=void 0===P?void 0:P,R=e.showAllBranchLabels,B=void 0===R?void 0:R,M=e.newTipLabelKey,D=void 0===M?void 0:M,F=e.streamDefinitionChange,z=void 0===F?void 0:F,V=e.branchStroke,W=void 0===V?void 0:V,G=e.tipStroke,U=void 0===G?void 0:G,q=e.fill,H=void 0===q?void 0:q,K=e.visibility,Q=void 0===K?void 0:K,$=e.tipRadii,Y=void 0===$?void 0:$,X=e.hoveredLegendSwatch,J=void 0===X?void 0:X,Z=e.branchThickness,ee=void 0===Z?void 0:Z,te=e.scatterVariables,ne=void 0===te?void 0:te,re=e.performanceFlags,ie=void 0===re?void 0:re,oe=e.newMeasurementsColorGrouping,ae=void 0===oe?void 0:oe,se=new Set,le={},ce=new Set,ue=j,he=500;if((Date.now()-this.timeLastRenderRequested<1e3||!0===ie.get("skipTreeAnimation"))&&(he=0),i&&(se.add(".branch").add(".tip").add(".conf"),ce.add("stroke").add("fill"),le.branchStroke=W,le.tipStroke=U,le.fill=H),a&&(se.add(".tip").add(".tipLabel").add(".branchLabel"),ce.add("visibility").add("cursor"),le.visibility=Q),l&&(se.add(".tip"),ce.add("r"),le.r=Y,this.params.showStreamTrees&&this.highlightStreamtreeRipples(J)),h&&(se.add(".branch").add(".conf"),ce.add("stroke-width"),le["stroke-width"]=ee),(O||j||L||g||b||x||a)&&(se.add(".tip").add(".branch.S").add(".branch.T").add(".branch"),se.add(".vaccineCross").add(".vaccineDottedLine").add(".conf"),se.add(".branchLabel").add(".tipLabel"),se.add(".grid").add(".regression"),ce.add("cx").add("cy").add("d").add("opacity").add("visibility")),d&&(this.params.confidence=!0),void 0!==B&&(this.params.showAllBranchLabels=B,se.add(".branchLabel")),D&&(this.callbacks.tipLabel=N(D),se.add(".tipLabel")),t=this.nodes,n=le,t.forEach(function(e,t){for(var r in e.update=!1,n){var i=n[r][t];i!==e[r]&&(e[r]=i,e.update=!0)}}),i&&(this.updateColorBy(),this.measurementsColorGrouping=ae),a&&this.regression&&(se.add(".regression"),this.calculateRegression()),g&&(this.nodes.forEach(function(e){e.inView=!1,e.update=!0}),this.zoomNode=g.n.hasChildren?g:g.n.parent.shell,(0,u.zF)(this.zoomNode,function(e){e.inView=!0})),(b||x||a)&&this.nodes.forEach(function(e){e.update=!0}),O||L||x||z?(0,u.PX)({nodes:this.nodes,focus:this.focus,streams:this.params.showStreamTrees&&this.streams}):this.params.showStreamTrees&&(i||a)&&(0,u.qO)(this.nodes,this.streams),(O||L)&&this.setDistance(O),(O||j||L||x||z)&&this.setLayout(j||this.layout,ne),ce.has("stroke-width")||O||j||x||L||g||b||z||a||d?this.mapToScreen():this.params.showStreamTrees&&(i||a)&&this.mapStreamsToScreen(),C&&("selected"===this.focus?this.hideTemporalSlice():this.showTemporalSlice()),z){for(var pe=0,de=["branchLabels","branchTee","branchStem","tips","tipLabels","vaccines"];pe<de.length;pe++){var fe,me,ye,ge=de[pe];null===(fe=this.groups)||void 0===fe||null===(me=fe[ge])||void 0===me||null===(ye=me.selectAll("*"))||void 0===ye||ye.remove()}this.addGrid(),this.drawBranches(),this.updateTipLabels(),this.drawTips(),this.drawBranchLabels(this.params.branchLabelKey),this.vaccines&&this.drawVaccines(),this.regression&&this.drawRegression(),this.confidencesInSVG&&this.removeConfidence(),this.drawStreams()}else{var ve={removeConfidences:m,showConfidences:d,newBranchLabellingKey:I};ve.timeSliceHasPotentiallyChanged=a||void 0!==O,ve.hideTipLabels=S||"none"===D,ue?this.modifySVGInStages(se,ce,he,1e3,ve):this.modifySVG(se,ce,he,ve),(this.params.showStreamTrees||i)&&this.drawStreams()}this.timeLastRenderRequested=Date.now()},ee.prototype.modifySVG=function(e,t,n,r){var i,o=this,a=[".tip",".vaccineDottedLine",".vaccineCross",".branch"];if(e.has(".branch.S")||e.has(".branch.T")){var s=e.has(".branch");s&&a.splice(a.indexOf(".branch"),1),[".S",".T"].forEach(function(r,a){e.has(".branch".concat(r))&&(i=s?function(e){M(".branch",t)(e),e.attr("d",function(e){return e.branch[a]})}:function(e){e.attr("d",function(e){return e.branch[a]})},D(o.svg,".branch".concat(r),i,n))})}a.forEach(function(r){e.has(r)&&(i=M(r,t),D(o.svg,r,i,n))}),r.hideTipLabels?this.removeTipLabels():e.has(".tipLabel")&&this.updateTipLabels(),e.has(".grid")&&(this.grid&&"unrooted"!==this.layout?this.addGrid():this.hideGrid()),e.has(".regression")&&(this.removeRegression(),this.regression&&this.drawRegression()),r.removeConfidences&&this.confidencesInSVG?this.removeConfidence():r.showConfidences&&!this.confidencesInSVG?this.drawConfidence():e.has(".conf")&&this.confidencesInSVG&&((0,O.ef)(!0,this.distance,this.layout)?(i=M(".conf",t),D(this.svg,".conf",i,n)):this.removeConfidence()),r.timeSliceHasPotentiallyChanged&&this.showTemporalSlice(),r.newBranchLabellingKey?(this.removeBranchLabels(),"none"!==r.newBranchLabellingKey&&this.drawBranchLabels(r.newBranchLabellingKey)):e.has(".branchLabel")&&this.updateBranchLabels(n),this.measurementsColorGrouping?this.drawMeasurementsColoringCrosshair():this.removeMeasurementsColoringCrosshair()},ee.prototype.modifySVGInStages=function(e,t,n,r,i){var o=this;e.delete(".tip"),this.hideGrid();var a=0,s=function(){o.drawBranches(),o.params.showGrid&&o.addGrid(),o.svg.selectAll(".tip").remove(),o.updateTipLabels(),o.drawTips(),o.vaccines&&o.drawVaccines(),o.measurementsColorGrouping&&o.drawMeasurementsColoringCrosshair(),o.showTemporalSlice(),o.regression&&o.drawRegression(),e.has(".branchLabel")&&o.drawBranchLabels(i.newBranchLabellingKey||o.params.branchLabelKey)};this.confidencesInSVG=!1,this.svg.selectAll(I(e).join(", ")).transition().duration(n).style("opacity",0).remove().on("start",function(){return a++}).on("end",function(){if(! --a){o.setClipMask();var e=M(".tip",t);D(o.svg,".tip",e,r),setTimeout(s,r)}}),this.hideTemporalSlice(),this.removeMeasurementsColoringCrosshair(),n||(0,c.O2)()},ee.prototype.render=function(e){var t=this,n=e.svg,r=e.layout,i=e.distance,o=e.focus,a=e.parameters,s=e.callbacks,l=e.branchThickness,c=e.visibility,h=e.drawConfidence,p=e.vaccines,d=e.branchStroke,f=e.tipStroke,m=e.tipFill,y=e.tipRadii,g=e.dateRange,v=e.scatterVariables,b=e.measurementsColorGrouping,w=e.streams,S=e.focusNodes;this.svg=n,this.params=E(E({},this.params),a),this.callbacks=s,this.vaccines=p?p.map(function(e){return e.shell}):void 0,this.measurementsColorGrouping=b,this.dateRange=g,this.streams=w,this.focus=o,this.focusNodes=S,this.nodes.forEach(function(e,n){e.branchStroke=d[n],e.tipStroke=f[n],e.fill=m[n],e.visibility=c[n],e["stroke-width"]=l[n],e.r=y?y[n]:t.params.tipRadius}),(0,u.PX)({nodes:this.nodes,focus:this.focus,streams:this.params.showStreamTrees&&w}),this.setDistance(i),this.setLayout(r,v),this.mapToScreen(),this.setClipMask(),this.params.showGrid&&(this.addGrid(),this.focus||this.showTemporalSlice()),this.drawBranches(),this.updateTipLabels(),this.drawTips(),this.drawStreams(),this.params.branchLabelKey&&this.drawBranchLabels(this.params.branchLabelKey),this.vaccines&&this.drawVaccines(),this.measurementsColorGrouping&&this.drawMeasurementsColoringCrosshair(),this.regression&&this.drawRegression(),this.confidencesInSVG=!1,h&&this.drawConfidence(),this.timeLastRenderRequested=Date.now()},ee.prototype.clearSVG=function(){this.svg.selectAll("*").remove()},ee.prototype.setClipMask=function(){var e=v(this.yScale.range(),2),t=e[0],n=e[1],r=v(this.xScale.range(),2),i=r[0],o=r[1];if(parseInt(i,10)>parseInt(o,10)){var a=[o,i];i=a[0],o=a[1]}var s=i-5,l=o-i+20,c=t-15,u=n-t+20;this.groups.clipPath?this.groups.clipPath.select("rect").attr("x",s).attr("y",c).attr("width",l).attr("height",u):(this.groups.clipPath=this.svg.append("g").attr("id","clipGroup"),this.groups.clipPath.append("clipPath").attr("id","treeClip").append("rect").attr("x",s).attr("y",c).attr("width",l).attr("height",u))},ee.prototype.drawTips=function(){var e=this.params;"tips"in this.groups||(this.groups.tips=this.svg.append("g").attr("id","tips").attr("clip-path","url(#treeClip)"));var t=(this.params.showStreamTrees?this.nodes.filter(function(e){return!e.n.inStream}):this.nodes).filter(function(e){return!e.n.hasChildren});this.groups.tips.selectAll(".tip").data(t).enter().append("circle").attr("class","tip").attr("id",function(e){return(0,u.ug)("tip",e.n.name)}).attr("cx",function(e){return e.xTip}).attr("cy",function(e){return e.yTip}).attr("r",function(e){return e.r}).on("mouseover",this.callbacks.onTipHover).on("mouseout",this.callbacks.onTipLeave).on("click",this.callbacks.onTipClick).style("pointer-events","auto").style("visibility",function(e){return e.visibility===p.uU?"visible":"hidden"}).style("fill",function(t){return t.fill||e.tipFill}).style("stroke",function(t){return t.tipStroke||e.tipStroke}).style("stroke-width",function(){return e.tipStrokeWidth}).style("cursor","pointer")},ee.prototype.drawBranches=function(){var e=this.params,t=(this.params.showStreamTrees?this.nodes.filter(function(e){return!e.n.inStream}):this.nodes).filter(function(e){return void 0!==e.displayOrder});"branchTee"in this.groups||(this.groups.branchTee=this.svg.append("g").attr("id","branchTee").attr("clip-path","url(#treeClip)")),"clock"===this.layout||"scatter"===this.layout||"unrooted"===this.layout?this.groups.branchTee.selectAll("*").remove():this.groups.branchTee.selectAll(".branch").data(t.filter(function(e){return e.n.hasChildren})).enter().append("path").attr("class","branch T").attr("id",function(e){return(0,u.ug)("branchT",e.n.name)}).attr("d",function(e){return e.branch[1]}).style("stroke",function(t){return t.branchStroke||e.branchStroke}).style("stroke-width",function(t){return t["stroke-width"]||e.branchStrokeWidth}).style("visibility",k).style("fill","none").style("pointer-events","auto").on("mouseover",this.callbacks.onBranchHover).on("mouseout",this.callbacks.onBranchLeave).on("click",this.callbacks.onBranchClick),this.groups.branchGradientDefs||(this.groups.branchGradientDefs=this.svg.append("defs")),this.groups.branchGradientDefs.selectAll("*").remove(),this.updateColorBy(),"branchStem"in this.groups||(this.groups.branchStem=this.svg.append("g").attr("id","branchStem").attr("clip-path","url(#treeClip)")),this.groups.branchStem.selectAll(".branch").data(t).enter().append("path").attr("class","branch S").attr("id",function(e){return(0,u.ug)("branchS",e.n.name)}).attr("d",function(e){return e.branch[0]}).style("stroke",function(t){return t.branchStroke?C(t):e.branchStroke}).style("stroke-linecap","round").style("stroke-width",function(t){return t["stroke-width"]||e.branchStrokeWidth}).style("visibility",k).style("cursor",function(e){return e.visibility===p.uU?"pointer":"default"}).style("pointer-events","auto").on("mouseover",this.callbacks.onBranchHover).on("mouseout",this.callbacks.onBranchLeave).on("click",this.callbacks.onBranchClick)},ee.prototype.drawVaccines=function(){var e=this.vaccines||[];this.params.showStreamTrees&&(e=e.filter(function(e){return!e.n.inStream})),e.length&&("vaccines"in this.groups||(this.groups.vaccines=this.svg.append("g").attr("id","vaccines")),this.groups.vaccines.selectAll(".vaccineCross").data(e).enter().append("path").attr("class","vaccineCross").attr("d",function(e){return e.vaccineCross}).style("stroke","#333").style("stroke-width",2*this.params.branchStrokeWidth).style("fill","none").style("cursor","pointer").style("pointer-events","auto").on("mouseover",this.callbacks.onTipHover).on("mouseout",this.callbacks.onTipLeave).on("click",this.callbacks.onTipClick))},ee.prototype.drawMeasurementsColoringCrosshair=function(){var e=this;"measurementsColoringCrosshair"in this.groups?this.removeMeasurementsColoringCrosshair():this.groups.measurementsColoringCrosshair=this.svg.append("g").attr("id","measurementsColoringCrosshairId");var t=this.nodes.filter(function(t){return!t.n.hasChildren&&t.n.name===e.measurementsColorGrouping});1===t.length?this.groups.measurementsColoringCrosshair.selectAll(".crosshair").data(t).enter().append("svg").attr("stroke","currentColor").attr("fill","currentColor").attr("strokeWidth","0").attr("viewBox","0 0 256 256").attr("height",function(e){return 5*e.r}).attr("width",function(e){return 5*e.r}).attr("x",function(e){return e.xTip-5*e.r/2}).attr("y",function(e){return e.yTip-5*e.r/2}).style("cursor","pointer").style("pointer-events","auto").on("mouseover",this.callbacks.onTipHover).on("mouseout",this.callbacks.onTipLeave).on("click",this.callbacks.onTipClick).append("path").attr("d","M128,20A108,108,0,1,0,236,128,108.12,108.12,0,0,0,128,20Zm12,191.13V184a12,12,0,0,0-24,0v27.13A84.18,84.18,0,0,1,44.87,140H72a12,12,0,0,0,0-24H44.87A84.18,84.18,0,0,1,116,44.87V72a12,12,0,0,0,24,0V44.87A84.18,84.18,0,0,1,211.13,116H184a12,12,0,0,0,0,24h27.13A84.18,84.18,0,0,1,140,211.13Z"):0===t.length?console.warn("Measurements coloring group ".concat(this.measurementsColorGrouping," doesn't match any tip names")):console.warn("Measurements coloring group ".concat(this.measurementsColorGrouping," matches multiple tips"))},ee.prototype.removeMeasurementsColoringCrosshair=function(){"measurementsColoringCrosshair"in this.groups&&this.groups.measurementsColoringCrosshair.selectAll("*").remove()},ee.prototype.drawRegression=function(){if(void 0!==this.regression.slope){var e,t,n,r=this.yScale(this.regression.intercept+this.xScale.domain()[0]*this.regression.slope),i=this.yScale(this.regression.intercept+this.xScale.domain()[1]*this.regression.slope),o="M "+this.xScale.range()[0].toString()+" "+r.toString()+" L "+this.xScale.range()[1].toString()+" "+i.toString();"regression"in this.groups||(this.groups.regression=this.svg.append("g").attr("id","regression").attr("clip-path","url(#treeClip)")),this.groups.regression.append("path").attr("d",o).attr("class","regression").style("fill","none").style("visibility","visible").style("stroke",this.params.regressionStroke).style("stroke-width",this.params.regressionWidth),this.groups.regression.append("text").text((e=this.regression,t=this.layout,n=this.yScale,"clock"===t?(0,u.Qh)(n)?"rate estimate: ".concat(e.slope.toExponential(2)," subs per site per year"):"rate estimate: ".concat((0,u.C2)(e.slope)," subs per year"):"intercept = ".concat(e.intercept.toPrecision(3),", slope = ").concat(e.slope.toPrecision(3),", R^2 = ").concat(e.r2.toPrecision(3)))).attr("class","regression").attr("x",this.xScale.range()[1]/2-75).attr("y",this.yScale.range()[0]+50).style("fill",this.params.regressionStroke).style("font-size",this.params.tickLabelSize+8).style("font-weight",400).style("font-family",this.params.fontFamily)}},ee.prototype.removeRegression=function(){"regression"in this.groups&&this.groups.regression.selectAll("*").remove()},ee.prototype.updateColorBy=function(){},ee.prototype.drawStreams=function(){var e=this,t=this.params.showStreamTrees?Object.keys(this.streams).reverse():[];if(t.length&&!("streams"in this.groups)?(this.groups.streams=this.svg.append("g").attr("id","streams"),this.groups.streamsLabels=this.svg.append("g").attr("id","stream-labels")):!t.length&&"streams"in this.groups&&(this.groups.streams.selectAll("*").remove(),this.groups.streamsLabels.selectAll("*").remove(),delete this.groups.streams,delete this.groups.streamsLabels),t.length){this.groups.streams.selectAll(".streamGroup").data(t,function(e){return String(e)}).join(function(e){var t=e.append("g").attr("id",function(e){return"stream".concat(e)}).attr("class","streamGroup");return t.append("g").attr("class","connector"),t.append("g").attr("class","ripples"),t},void 0,function(e){return e.call(function(e){return e.transition("500").style("opacity",0).remove()})});var n,r=(0,y.A)().x(function(e){return e.x}).y0(function(e){return e.y0}).y1(function(e){return e.y1}),i=function(t,n){if(0===t.n.streamNodeCounts.visible)return"";var r=e.yScale(t.displayOrder);if("backbone"===n){var i=t.streamRipples.at(0).at(0).x,o=t.streamRipples.at(0).at(-1).x;return"M".concat(i,",").concat(r,"H").concat(o)}if("hidden"===k(t))return"";var a=t.streamRipples[0][0].x,s=e.streams[t.n.streamName].parentStreamName;if(s){var l=t.xBase,c=e.yScale(e.nodes[e.streams[s].startNode].displayOrder);return"M".concat(l,",").concat(c,"L").concat(l,",").concat(r,"L").concat(a,",").concat(r)}return"M".concat(t.xBase,",").concat(r,"H").concat(a)},o=function(e){var t="undefined"!=typeof Symbol&&e[Symbol.iterator]||e["@@iterator"];if(!t){if(Array.isArray(e)||(t=b(e))){t&&(e=t);var n=0,r=function(){};return{s:r,n:function(){return n>=e.length?{done:!0}:{done:!1,value:e[n++]}},e:function(e){throw e},f:r}}throw new TypeError("Invalid attempt to iterate non-iterable instance.\nIn order to be iterable, non-array objects must have a [Symbol.iterator]() method.")}var i,o=!0,a=!1;return{s:function(){t=t.call(e)},n:function(){var e=t.next();return o=e.done,e},e:function(e){a=!0,i=e},f:function(){try{o||null==t.return||t.return()}finally{if(a)throw i}}}}(t);try{var a=function(){var t=n.value,o=e.nodes[e.streams[t].startNode],a=e.callbacks;e.groups.streams.select("#".concat(CSS.escape("stream".concat(t)))).select(".connector").selectAll(".connectorPath").data([o,o],function(e,t){return 0===t?"joiner":"backbone"}).join(function(t){return t.append("path").attr("class","connectorPath").attr("d",function(e,t){return i(e,0===t?"joiner":"backbone")}).attr("stroke-width",e.params.branchStrokeWidth).style("stroke",function(t,n){return 0===n?t.branchStroke:e.params.branchStroke}).attr("fill","None").style("cursor","pointer").style("pointer-events","auto").on("mouseover",function(e,t,n){a.onStreamHover(o,t,Array.from(n),!0)}).on("mouseout",function(e,t,n){a.onStreamLeave(o,t,Array.from(n),!0)}).on("click",a.onBranchClick)},function(t){return t.call(function(t){return t.transition("500").attr("d",function(e,t){return i(e,0===t?"joiner":"backbone")}).style("stroke",function(t,n){return 0===n?t.branchStroke:e.params.branchStroke}).attr("stroke-width",e.params.branchStrokeWidth)})},function(e){return e.remove()}),e.groups.streams.select("#".concat(CSS.escape("stream".concat(t)))).select(".ripples").selectAll(".ripple").data(o.streamRipples,function(e){return String(e.key)}).join(function(t){return t.append("path").attr("class","ripple").attr("d",function(e){return r(e)}).attr("fill",function(e,t){return o.n.streamCategories[t].color}).on("mouseover",function(t,n,r){e.callbacks.onStreamHover(o,n,Array.from(r),!1)}).on("mouseout",function(t,n,r){e.callbacks.onStreamLeave(o,n,Array.from(r),!1)}).style("cursor","pointer").style("pointer-events","auto").on("click",function(){return e.callbacks.onBranchClick(o)})},function(e){return e.call(function(e){return e.transition("500").attr("d",function(e){return r(e)})})},function(e){return e.remove()})};for(o.s();!(n=o.n()).done;)a()}catch(e){o.e(e)}finally{o.f()}var s=t.map(function(t){var n=e.nodes[e.streams[t].startNode];if(0===n.n.streamNodeCounts.visible)return null;var r,i=e.zoomNode.n.name===n.n.name?"start":"middle",o=(r=n,r.streamRipples[0].reduce(function(e,t,n){var i=v(e,2),o=i[0],a=i[1],s=r.streamRipples.at(-1)[n].y1-t.y0;return 0===n?[0,s]:s>a?[n,s]:[o,a]},[void 0,void 0]))[1],a=Math.floor(Math.max(10,Math.min(o/2,24))),s=10===a?"hidden":"visible";return{phyloNode:n,streamName:t,x:n.streamRipples.at(0).at(0).x,y:e.yScale(n.displayOrder),textAnchor:i,fontSize:a,visibility:s}}).filter(function(e){return!!e});this.groups.streamsLabels.selectAll(".labelText").data(s,function(e){return String(e.streamName)}).join(function(e){return e.append("text").attr("class","labelText").attr("id",function(e){return"label".concat(e.streamName)}).attr("x",function(e){return e.x}).attr("y",function(e){return e.y}).attr("text-anchor",function(e){return e.textAnchor}).attr("dominant-baseline","ideographic").attr("font-size",function(e){return e.fontSize}).attr("visibility",function(e){return e.visibility}).text(function(e){return e.phyloNode.n.streamName}).style("pointer-events","none")},function(e){return e.call(function(e){return e.attr("x",function(e){return e.x}).attr("y",function(e){return e.y}).attr("text-anchor",function(e){return e.textAnchor}).attr("visibility",function(e){return e.visibility}).attr("font-size",function(e){return e.fontSize})})},function(e){return e.remove()})}},ee.prototype.highlightStreamtreeRipples=function(e){var t,n=null===(t=this.groups)||void 0===t?void 0:t.streams;if(!n)return null;if(!1!==e){var r=e+"_";n.selectAll(".ripple").each(function(e){e.key.startsWith(r)||(0,m.A)(this).style("opacity",.3)})}else n.selectAll(".ripple").style("opacity",1)},ee.prototype.setDistance=function(e){this.nodes.forEach(function(e){e.update=!0}),e&&(this.distance=e),["div","num_date"].includes(this.distance)||(console.error("Tree distance measure not set or invalid. Using `div`."),this.distance="div"),"div"===this.distance?this.nodes.forEach(function(e){e.depth=(0,j.Ue)(e.n),e.pDepth=(0,j.Ue)((0,u.k9)(e.n)),e.conf=[e.depth,e.depth]}):this.nodes.forEach(function(e){e.depth=(0,j.hu)(e.n,"num_date"),e.pDepth=(0,j.hu)((0,u.k9)(e.n),"num_date"),e.conf=(0,j.hu)(e.n,"num_date",{confidence:!0})||[e.depth,e.depth]}),this.vaccines&&this.vaccines.forEach(function(e){e.crossDepth=e.depth})},ee.prototype.setLayout=function(e,t){void 0!==e&&e===this.layout||this.nodes.forEach(function(e){e.update=!0}),this.layout=void 0===e?"rect":e,this.regression=void 0,t&&(this.scatterVariables=function(e){for(var t=1;t<arguments.length;t++){var n=null!=arguments[t]?arguments[t]:{};t%2?H(Object(n),!0).forEach(function(t){K(e,t,n[t])}):Object.getOwnPropertyDescriptors?Object.defineProperties(e,Object.getOwnPropertyDescriptors(n)):H(Object(n)).forEach(function(t){Object.defineProperty(e,t,Object.getOwnPropertyDescriptor(n,t))})}return e}({},t)),"clock"===this.layout&&(this.scatterVariables.x="num_date",this.scatterVariables.y="div"),"rect"===this.layout?this.rectangularLayout():"clock"===this.layout||"scatter"===this.layout?this.scatterplotLayout():"radial"===this.layout?this.radialLayout():"unrooted"===this.layout&&this.unrootedLayout()},ee.prototype.rectangularLayout=function(){this.nodes.forEach(function(e){e.y=e.displayOrder,e.x=e.depth,e.px=e.pDepth,e.py=e.y}),this.vaccines&&this.vaccines.forEach(function(e){e.xCross=e.crossDepth,e.yCross=e.y})},ee.prototype.scatterplotLayout=function(){if(this.scatterVariables){var e,t="displayOrder"===this.scatterVariables.x||"displayOrder"===this.scatterVariables.y?(0,u.tK)(this.nodes):void 0,n=G(this.nodes);try{for(n.s();!(e=n.n()).done;){var r=e.value;if("div"===this.scatterVariables.x)r.x=(0,j.Ue)(r.n),r.px=(0,j.Ue)((0,u.k9)(r.n));else if("gt"===this.scatterVariables.x)r.x=r.n.currentGt,r.px=(0,u.k9)(r.n).currentGt;else if("displayOrder"===this.scatterVariables.x){var i=W(t(r),2);r.x=i[0],r.px=i[1]}else if(r.x=(0,j.hu)(r.n,this.scatterVariables.x),r.px=(0,j.hu)((0,u.k9)(r.n),this.scatterVariables.x),this.scatterVariables.xTemporal){var o=[(0,f.DK)(r.x),(0,f.DK)(r.px)];r.x=o[0],r.px=o[1]}if("div"===this.scatterVariables.y)r.y=(0,j.Ue)(r.n),r.py=(0,j.Ue)((0,u.k9)(r.n));else if("gt"===this.scatterVariables.y)r.y=r.n.currentGt,r.py=(0,u.k9)(r.n).currentGt;else if("displayOrder"===this.scatterVariables.y){var a=W(t(r),2);r.y=a[0],r.py=a[1]}else if(r.y=(0,j.hu)(r.n,this.scatterVariables.y),r.py=(0,j.hu)((0,u.k9)(r.n),this.scatterVariables.y),this.scatterVariables.yTemporal){var s=[(0,f.DK)(r.y),(0,f.DK)(r.py)];r.y=s[0],r.py=s[1]}}}catch(e){n.e(e)}finally{n.f()}this.vaccines&&this.vaccines.forEach(function(e){e.xCross=e.x,e.yCross=e.y}),this.scatterVariables.showRegression&&this.calculateRegression()}else console.error("Scatterplot called without variables")},ee.prototype.unrootedLayout=function(){var e=J(this.nodes[0].n),t=1.5*Math.PI,n=this.nodes[0].n.children;this.nodes.forEach(function(e){e.x=void 0,e.y=void 0,e.px=void 0,e.py=void 0});for(var r=0;r<n.length;r++){var i=n[r].shell;if(i.w=2*Math.PI*J(i.n)/e,i.w>0){var o=i.depth-this.nodes[0].depth;i.px=o*Math.cos(t+.5*i.w),i.py=o*Math.sin(t+.5*i.w),i.tau=t,Q(i,e),t+=i.w}}this.vaccines&&this.vaccines.forEach(function(e){var t=e.crossDepth-e.depth;e.xCross=e.px+t*Math.cos(e.tau+.5*e.w),e.yCross=e.py+t*Math.sin(e.tau+.5*e.w)}),this.nodes.forEach(function(e){delete e.tau,delete e.w})},ee.prototype.radialLayout=function(){var e,t=this,n=Math.max.apply(Math,function(e){if(Array.isArray(e))return q(e)}(e=this.nodes.map(function(e){return e.displayOrder}).filter(function(e){return e}))||function(e){if("undefined"!=typeof Symbol&&null!=e[Symbol.iterator]||null!=e["@@iterator"])return Array.from(e)}(e)||U(e)||function(){throw new TypeError("Invalid attempt to spread non-iterable instance.\nIn order to be iterable, non-array objects must have a [Symbol.iterator]() method.")}()),r=this.nodes[0].depth;this.nodes.forEach(function(e){var t=1.9*Math.PI*e.displayOrderRange[0]/n,i=1.9*Math.PI*e.displayOrderRange[1]/n;e.angle=1.9*Math.PI*e.displayOrder/n,e.y=(e.depth-r)*Math.cos(e.angle),e.x=(e.depth-r)*Math.sin(e.angle),e.py=e.y*(e.pDepth-r)/(e.depth-r+1e-15),e.px=e.x*(e.pDepth-r)/(e.depth-r+1e-15),e.yCBarStart=(e.depth-r)*Math.cos(t),e.xCBarStart=(e.depth-r)*Math.sin(t),e.yCBarEnd=(e.depth-r)*Math.cos(i),e.xCBarEnd=(e.depth-r)*Math.sin(i),e.smallBigArc=Math.abs(i-t)>1*Math.PI}),this.vaccines&&this.vaccines.forEach(function(e){"div"===t.distance?(e.xCross=e.x,e.yCross=e.y):(e.xCross=(e.crossDepth-r)*Math.sin(e.angle),e.yCross=(e.crossDepth-r)*Math.cos(e.angle))})},ee.prototype.setScales=function(){"scatter"!==this.layout||this.scatterVariables.xContinuous?this.xScale=(0,F.m4)():this.xScale=(0,F.hq)().round(!1).align(.5).padding(.5),"scatter"!==this.layout||this.scatterVariables.yContinuous?this.yScale=(0,F.m4)():this.yScale=(0,F.hq)().round(!1).align(.5).padding(.5);var e=parseInt(this.svg.attr("width"),10),t=parseInt(this.svg.attr("height"),10);if("radial"===this.layout||"unrooted"===this.layout){var n=e-this.margins.left-this.margins.right,r=t-this.margins.bottom-this.margins.top,i=Math.min(n,r),o=n-i,a=r-i;this.xScale.range([.5*o+this.margins.left,e-.5*o-this.margins.right]),this.yScale.range([.5*a+this.margins.top,t-.5*a-this.margins.bottom])}else this.params.orientation[0]>0?this.xScale.range([this.margins.left,e-this.margins.right]):this.xScale.range([e-this.margins.right,this.margins.left]),this.params.orientation[1]>0?this.yScale.range([this.margins.top,t-this.margins.bottom]):this.yScale.range([t-this.margins.bottom,this.margins.top])},ee.prototype.mapToScreen=function(){var e,t=this,n=this.nodes.filter(function(e){return!e.n.hasChildren}).filter(function(e){return e.inView});this.margins={left:"scatter"===this.layout||"clock"===this.layout?40:5,right:5+X(this.params,n),top:"radial"===this.layout?10:15,bottom:35},this.setScales(),this.setClipMask();var r,i,o,a,s="selected"===this.focus&&("rect"===this.layout||"radial"===this.layout),l=this.focusNodes;if(e=s&&l?l.nodes.map(function(e){return t.nodes[e]}).filter(function(e){return void 0!==e.y&&void 0!==e.x}):this.nodes.filter(function(e){return e.inView&&void 0!==e.y&&void 0!==e.x}),"scatter"===this.layout&&!1===this.scatterVariables.showBranches&&(e=e.filter(function(e){return!e.n.hasChildren})),"scatter"!==this.layout||this.scatterVariables.xContinuous){var c=1e6,h=-1e5;e.forEach(function(e){e.x<c&&(c=e.x),e.x>h&&(h=e.x)}),c!==h||this.params.showStreamTrees&&e[0].n.streamName||(c-=.005,h+=.005);var p=1e-8;(o=h-c)<p&&(h=p-c,o=p),"rect"===this.layout&&0!==this.zoomNode.n.arrayIdx&&(c-=(h-c)/20),r=[c,h]}else{var d=new Set(e.map(function(e){return e.x}));$(r=this.scatterVariables.xDomain.filter(function(e){return d.has(e)}),this.xScale)}if("scatter"!==this.layout||this.scatterVariables.yContinuous){var f=1e6,m=-1e5;if(e.forEach(function(e){e.y<f&&(f=e.y),e.y>m&&(m=e.y)}),n.length<30){var y=.05*(m-f);f-=y,m+=y}a=m-f,i=[f,m]}else{var g=new Set(e.map(function(e){return e.y}));$(i=this.scatterVariables.yDomain.filter(function(e){return g.has(e)}),this.yScale)}if("radial"===this.layout||"unrooted"===this.layout){var v=Math.max(a,o),b=o>a?.5*(o-a):0,w=o<a?.5*(a-o):0;r=[r[0]-w,r[0]+v-w],i=[i[0]-b,i[0]+v-b]}if("clock"!==this.layout&&"scatter"!==this.layout||i.reverse(),this.params.showStreamTrees)for(var S=0,E=Object.values(this.streams);S<E.length;S++){var x=E[S],k=this.nodes[x.startNode];if(k.inView){var C=k.n.streamPivots;C.at(0)<r[0]&&(r[0]=C.at(0)),C.at(-1)>r[1]&&(r[1]=C.at(-1)),k.displayOrderRange[0]<i[0]&&(i[0]=k.displayOrderRange[0]),k.displayOrderRange[1]>i[1]&&(i[1]=k.displayOrderRange[1])}}this.xScale.domain(r),this.yScale.domain(i);var T=this.yScale.range()[1]+100,O=this.xScale.range()[0]-100;if(this.nodes.forEach(function(e){e.xTip=t.xScale(e.x),e.yTip=t.yScale(e.y),e.xBase=t.xScale(e.px),e.yBase=t.yScale(e.py),e.rot=180*Math.atan2(e.yTip-e.yBase,e.xTip-e.xBase)/Math.PI}),"scatter"===this.layout&&(this.scatterVariables.yContinuous||Y("y",this.yScale,this.nodes),this.scatterVariables.xContinuous||Y("x",this.xScale,this.nodes),this.nodes.forEach(function(e){isNaN(e.xTip)&&(e.xTip=O),isNaN(e.yTip)&&(e.yTip=T),isNaN(e.xBase)&&(e.xBase=O),isNaN(e.yBase)&&(e.yBase=T)})),this.vaccines&&this.vaccines.forEach(function(e){var n=t.xScale(e.xCross),r=t.yScale(e.yCross);e.vaccineCross=" M ".concat(n-6,",").concat(r-6," L ").concat(n+6,",").concat(r+6," M ").concat(n-6,",").concat(r+6," L ").concat(n+6,",").concat(r-6)}),"unrooted"===this.layout)this.nodes.forEach(function(e){e.branch=[" M "+e.xBase.toString()+","+e.yBase.toString()+" L "+e.xTip.toString()+","+e.yTip.toString(),""]});else if("clock"===this.layout||"scatter"===this.layout)this.scatterVariables.showBranches?this.nodes.forEach(function(e){e.branch=e.xBase===O||e.xTip===O||e.yBase===T||e.yTip===T?["",""]:[" M "+e.xBase.toString()+","+e.yBase.toString()+" L "+e.xTip.toString()+","+e.yTip.toString(),""]}):this.nodes.forEach(function(e){e.branch=["",""]});else if("rect"===this.layout)this.nodes.forEach(function(e){var n=.5*((0,u.k9)(e.n).shell["stroke-width"]-e["stroke-width"])||0,r=[t.yScale(e.displayOrderRange[0]),t.yScale(e.displayOrderRange[1])];e.branch=[" M ".concat(e.xBase-n,",").concat(e.yBase," L ").concat(e.xTip,",").concat(e.yTip+.01)," M ".concat(e.xTip,",").concat(r[0]," L ").concat(e.xTip,",").concat(r[1])],t.params.confidence&&(e.confLine=" M ".concat(t.xScale(e.conf[0]),",").concat(e.yBase," L ").concat(t.xScale(e.conf[1]),",").concat(e.yTip))});else if("radial"===this.layout){var _=this.nodes[0].depth,j=this.nodes.map(function(e){return.5*((0,u.k9)(e.n).shell["stroke-width"]-e["stroke-width"])||0});this.nodes.forEach(function(e,n){e.branch=[" M "+(e.xBase-j[n]*Math.sin(e.angle)).toString()+" "+(e.yBase-j[n]*Math.cos(e.angle)).toString()+" L "+e.xTip.toString()+" "+e.yTip.toString(),""],e.n.hasChildren&&(e.branch[1]=" M "+t.xScale(e.xCBarStart).toString()+" "+t.yScale(e.yCBarStart).toString()+" A "+(t.xScale(e.depth)-t.xScale(_)).toString()+" "+(t.yScale(e.depth)-t.yScale(_)).toString()+" 0 "+(e.smallBigArc?"1 ":"0 ")+" 1  "+t.xScale(e.xCBarEnd).toString()+","+t.yScale(e.yCBarEnd).toString())})}this.params.showStreamTrees&&this.mapStreamsToScreen()},ee.prototype.mapStreamsToScreen=function(){for(var e=this,t=function(){var t=r[n],i=e.nodes[t.startNode];i.streamRipples=i.rippleDisplayOrders.map(function(t,n){return Object.assign([],t.map(function(t,n){var r=W(t,2),o=r[0],a=r[1];return{x:e.xScale(i.n.streamPivots[n]),y0:e.yScale(o),y1:e.yScale(a)}}),{key:i.n.streamCategories[n].name+"_"+e.streams[z.vv]})})},n=0,r=Object.values(this.streams);n<r.length;n++)t()},ee.prototype.calculateRegression=function(){"clock"===this.layout?this.regression=function(e){var t=e.filter(function(e){return!e.n.hasChildren&&e.visibility===p.uU}),n=t.length;if(0===n)return{slope:void 0,intercept:void 0,r2:void 0};var r=e[0].x,i=(0,d.A)(t.map(function(e){return e.y*(e.x-r)}))/n/((0,d.A)(t.map(function(e){return(e.x-r)*(e.x-r)}))/n);return{slope:i,intercept:-r*i,r2:void 0}}(this.nodes):this.regression=function(e){var t=e.filter(function(e){return!e.n.hasChildren&&void 0!==e.x&&void 0!==e.y&&e.visibility===p.uU}),n=t.length;if(0===n)return{slope:void 0,intercept:void 0,r2:void 0};var r=(0,d.A)(t.map(function(e){return e.x}))/n,i=(0,d.A)(t.map(function(e){return e.y}))/n,o=(0,d.A)(t.map(function(e){return(e.x-r)*(e.y-i)}))/(0,d.A)(t.map(function(e){return Math.pow(e.x-r,2)})),a=i-o*r,s=1-(0,d.A)(t.map(function(e){return Math.pow(e.y-(a+o*e.x),2)}))/(0,d.A)(t.map(function(e){return Math.pow(e.y-i,2)}));return{slope:o,intercept:a,r2:s}}(this.nodes)},ee.prototype.removeConfidence=function(e){this.confidencesInSVG=!1,"confidenceIntervals"in this.groups&&(e?this.groups.confidenceIntervals.selectAll("*").transition().duration(e).style("opacity",0).remove():this.groups.confidenceIntervals.selectAll("*").remove())},ee.prototype.drawConfidence=function(e){var t=this;this.confidencesInSVG=!0,"confidenceIntervals"in this.groups||(this.groups.confidenceIntervals=this.svg.append("g").attr("id","confidenceIntervals")),e?(this.groups.confidenceIntervals.selectAll(".conf").data(this.nodes).enter().call(function(e){return t.drawSingleCI(e,0)}),this.groups.confidenceIntervals.transition().duration(e).style("opacity",.5)):this.groups.confidenceIntervals.selectAll(".conf").data(this.nodes).enter().call(function(e){return t.drawSingleCI(e,.5)})},ee.prototype.drawSingleCI=function(e,t){e.append("path").attr("class","conf").attr("id",function(e){return(0,u.ug)("conf",e.n.name)}).attr("d",function(e){return e.confLine}).style("stroke",function(e){return e.branchStroke||"#888"}).style("opacity",t).style("fill","none").style("stroke-width",h).style("pointer-events","none")},ee.prototype.drawBranchLabels=function(e){var t=this;this.params.branchLabelKey=e;var n=A(e),r=L(e),i=P(e,this.params.showAllBranchLabels,this.layout,this.zoomNode.n.tipCount);"branchLabels"in this.groups||(this.groups.branchLabels=this.svg.append("g").attr("id","branchLabels").attr("clip-path","url(#treeClip)"));var o=(this.params.showStreamTrees?this.nodes.filter(function(e){return!e.n.inStream}):this.nodes).filter(function(t){return 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i={},o={},a=e?n.tree:n.treeToo,s=e?r.tree:r.treeToo,l=a.idxOfInViewRootNode!==s.idxOfInViewRootNode,c=n.dateMinNumeric!==r.dateMinNumeric||n.dateMaxNumeric!==r.dateMaxNumeric,u=n.filters!==r.filters;if(t.dateRange=[r.dateMinNumeric,r.dateMaxNumeric],n.focus!==r.focus&&(t.focus=r.focus,i.focusChange=!0),t.focusNodes=s.focusNodes,!s.nodeColorsVersion||a.nodeColorsVersion===s.nodeColorsVersion&&r.colorByConfidence===n.colorByConfidence||(i.changeColorBy=!0,i.branchStroke=(0,f.zY)(s,!0,r.colorByConfidence,r.colorBy),i.tipStroke=(0,f.zY)(s,!1,r.colorByConfidence,r.colorBy),i.fill=i.tipStroke.map(f.rQ),i.newMeasurementsColorGrouping=(0,ie.DM)(r.colorBy)?(0,ie.fN)(r.colorBy):void 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PointerEvent&&window.event.shiftKey)this.props.dispatch({type:se.S$,name:e.n.name,idx:e.n.arrayIdx,isBranch:!0,treeId:e.that.id});else{var t=1===e.that.params.orientation[0],n=(0,u.bP)(e.n)===e.n.arrayIdx;if(n&&this.props.showStreamTrees){var r=this.props.tree.streams[e.n.streamName].parentStreamName;if(r){var i=this.props.tree.streams[r].startNode;return this.props.dispatch((0,o.nj)({root:[i,void 0]}))}}var a=n?(0,u.T$)(e.n,this.props.distanceMeasure,t?this.props.tree.observedMutations:this.props.treeToo.observedMutations).arrayIdx:e.n.arrayIdx,s=t?[a,void 0]:[void 0,a];this.props.dispatch((0,o.nj)({root:s}))}},pe=function(e){(function(e){e&&T(e,e.n.parent.shell.branchStroke,e.branchStroke)})(e),this.props.temporalConfidence.exists&&this.props.temporalConfidence.display&&!this.props.temporalConfidence.on&&(1===e.that.params.orientation[0]?this.state.tree:this.state.treeToo).removeConfidence(),this.setState({hoveredNode:null})},de=function(e){var t=1===e.that.params.orientation[0]?this.state.tree:this.state.treeToo;this.state.hoveredNode&&t.svg.select("#"+(0,u.ug)("tip",e.n.name)).attr("r",function(e){return e.r}),this.setState({hoveredNode:null})},fe=function(e){e.isBranch||(e.existingFilterState?"inactive"===e.existingFilterState&&this.props.dispatch((0,o.$h)("inactivate",p.Uf,[e.name])):this.props.dispatch((0,o.$h)("remove",p.Uf,[e.name]))),this.props.dispatch({type:se.j_})};function me(e,t,n,r){var i,o;r?(0,m.A)(n[0]).style("stroke",(0,f._5)(e.branchStroke)):n.forEach(function(n,r){r===t?(0,m.A)(n).attr("fill",(0,f._5)(e.n.streamCategories[t].color)):(0,m.A)(n).style("opacity",.3)});var a=ge(e);"hidden"===(null===(i=a.data())||void 0===i||null===(o=i.at(0))||void 0===o?void 0:o.visibility)&&(a.attr("visibility","visible"),a.attr("font-size",16)),this.setState({hoveredNode:{node:e,isBranch:r,streamDetails:{x:ae.f0.layerX,y:ae.f0.layerY,categoryIndex:t}}})}function ye(e,t,n,r){var i,o;r?(0,m.A)(n[0]).style("stroke",e.branchStroke):n.forEach(function(n,r){r===t?(0,m.A)(n).attr("fill",e.n.streamCategories[t].color):(0,m.A)(n).style("opacity",1)});var a=ge(e);"hidden"===(null===(i=a.data())||void 0===i||null===(o=i.at(0))||void 0===o?void 0:o.visibility)&&a.attr("visibility","hidden"),this.setState({hoveredNode:null})}function ge(e){return e.that.groups.streamsLabels.select("#".concat(CSS.escape("label".concat(e.n.streamName))))}n(71595);var ve=function(e,t,n,r){var i=t?e.domRefs.mainTree:e.domRefs.secondTree,o=t?r.tree:r.treeToo;if(o.loaded){var a=r.canRenderBranchLabels;Object.prototype.hasOwnProperty.call(r.scatterVariables,"showBranches")&&!1===r.scatterVariables.showBranches&&(a=!1);var s=(0,f.zY)(o,!1,r.colorByConfidence,r.colorBy);n.render({svg:(0,m.A)(i),layout:r.layout,distance:r.distanceMeasure,focus:r.focus,parameters:{grid:!0,confidence:r.temporalConfidence.display,branchLabelKey:a&&r.selectedBranchLabel,showAllBranchLabels:r.showAllBranchLabels,orientation:t?[1,1]:[-1,1],tipLabels:!0,showTipLabels:!0,showStreamTrees:r.showStreamTrees},callbacks:{onTipHover:le.bind(e),onTipClick:ce.bind(e),onBranchHover:ue.bind(e),onBranchClick:he.bind(e),onBranchLeave:pe.bind(e),onTipLeave:de.bind(e),onStreamHover:me.bind(e),onStreamLeave:ye.bind(e),tipLabel:N(r.tipLabelKey)},branchThickness:o.branchThickness,visibility:o.visibility,drawConfidence:r.temporalConfidence.on,vaccines:o.vaccines,branchStroke:(0,f.zY)(o,!0,r.colorByConfidence,r.colorBy),tipStroke:s,tipFill:s.map(f.rQ),tipRadii:o.tipRadii,dateRange:[r.dateMinNumeric,r.dateMaxNumeric],scatterVariables:r.scatterVariables,measurementsColorGrouping:(0,ie.DM)(r.colorBy)?(0,ie.fN)(r.colorBy):void 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t=o,(n=[{key:"shouldComponentUpdate",value:function(e){return this.props.width!==e.width||this.props.height!==e.height||this.props.leftTreeName!==e.leftTreeName||this.props.rightTreeName!==e.rightTreeName}},{key:"drawLines",value:function(e){e||(e=this.props);var t=e.lookup.length>750?.25:e.lookup.length>100?.5:1;(0,m.A)(this.d3ref).selectAll("*").remove();var n=function(e){return function(t){var n=e.leftNodes[t[0]].shell,r=e.rightNodes[t[1]].shell;return"M ".concat(n.xTip,",").concat(n.yTip," H ").concat(e.width/2-e.spaceBetweenTrees/2," L ").concat(e.width/2+e.spaceBetweenTrees/2,",").concat(r.yTip," H ").concat(e.width/2+e.spaceBetweenTrees/2+r.xTip)}}(e);(0,m.A)(this.d3ref).selectAll(".tangleLine").data(e.lookup).enter().append("path").attr("class","tangleLine").attr("d",n).attr("stroke-width",t).attr("stroke",function(t){return 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r.createElement("div",{id:"TangleContainer"},r.createElement("div",{id:"MainTreeTitle",style:Se(Se({},t),{},{left:n[0],transform:"translateX(-100%)"})},this.props.leftTreeName),r.createElement("div",{id:"SecondTreeTitle",style:Se(Se({},t),{},{left:n[1]})},this.props.rightTreeName),r.createElement("div",{id:"TangleSvgContainer",style:{position:"absolute",left:this.state.left,top:this.state.top,zIndex:100,pointerEvents:"none"}},r.createElement("svg",{id:"Tangle",style:{cursor:"default",width:this.props.width,height:this.props.height},ref:function(t){e.d3ref=t}})))}}])&&xe(t.prototype,n),Object.defineProperty(t,"prototype",{writable:!1}),o}(r.Component);var Ae=n(41916),Le=function(e,t){for(var n=0,r=0,i=0,o=0,a=0,s=0,l=0;l<t.nodes.length;l++){var c=t.nodes[l];if(!c.n.children&&e.strainToNode[c.n.name]){var u=e.strainToNode[c.n.name].displayOrder,h=c.displayOrder;n++,r+=u,i+=h,o+=Math.pow(u,2),a+=Math.pow(h,2),s+=u*h}}return 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