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alignment.js

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A suite of reusable [React](http://reactjs.org/) components for creating a variety of visualizations involving [multiple sequence alignments](https://en.wikipedia.org/wiki/Multiple_sequence_alignment). [View the live demo here](http://alignment.hyphy.org/

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"use strict"; Object.defineProperty(exports, "__esModule", { value: true }); exports["default"] = void 0; var _react = _interopRequireWildcard(require("react")); var _fasta = _interopRequireDefault(require("../helpers/fasta")); var _computeLabelWidth = _interopRequireDefault(require("../helpers/computeLabelWidth")); var _BaseAlignment = _interopRequireDefault(require("./BaseAlignment.js")); var _SiteAxis = _interopRequireDefault(require("./SiteAxis.js")); var _Placeholder = _interopRequireDefault(require("./Placeholder.js")); var _SequenceAxis = _interopRequireDefault(require("./SequenceAxis.js")); var _ScrollBroadcaster = _interopRequireDefault(require("./../helpers/ScrollBroadcaster")); var _colors = require("./../helpers/colors"); var _nucleotideComposition = require("./../helpers/nucleotideComposition"); var _BaseSiteBarPlot = _interopRequireDefault(require("./BaseSiteBarPlot.js")); var _SitePlotAxis = _interopRequireDefault(require("./SitePlotAxis.js")); function _interopRequireDefault(obj) { return obj && obj.__esModule ? obj : { "default": obj }; } function _getRequireWildcardCache() { if (typeof WeakMap !== "function") return null; var cache = new WeakMap(); _getRequireWildcardCache = function _getRequireWildcardCache() { return cache; }; return cache; } function _interopRequireWildcard(obj) { if (obj && obj.__esModule) { return obj; } if (obj === null || _typeof(obj) !== "object" && typeof obj !== "function") { return { "default": obj }; } var cache = _getRequireWildcardCache(); if (cache && cache.has(obj)) { return cache.get(obj); } var newObj = {}; var hasPropertyDescriptor = Object.defineProperty && Object.getOwnPropertyDescriptor; for (var key in obj) { if (Object.prototype.hasOwnProperty.call(obj, key)) { var desc = hasPropertyDescriptor ? Object.getOwnPropertyDescriptor(obj, key) : null; if (desc && (desc.get || desc.set)) { Object.defineProperty(newObj, key, desc); } else { newObj[key] = obj[key]; } } } newObj["default"] = obj; if (cache) { cache.set(obj, newObj); } return newObj; } function _typeof(obj) { "@babel/helpers - typeof"; if (typeof Symbol === "function" && typeof Symbol.iterator === "symbol") { _typeof = function _typeof(obj) { return typeof obj; }; } else { _typeof = function _typeof(obj) { return obj && typeof Symbol === "function" && obj.constructor === Symbol && obj !== Symbol.prototype ? "symbol" : typeof obj; }; } return _typeof(obj); } function _classCallCheck(instance, Constructor) { if (!(instance instanceof Constructor)) { throw new TypeError("Cannot call a class as a function"); } } function _defineProperties(target, props) { for (var i = 0; i < props.length; i++) { var descriptor = props[i]; descriptor.enumerable = descriptor.enumerable || false; descriptor.configurable = true; if ("value" in descriptor) descriptor.writable = true; Object.defineProperty(target, descriptor.key, descriptor); } } function _createClass(Constructor, protoProps, staticProps) { if (protoProps) _defineProperties(Constructor.prototype, protoProps); if (staticProps) _defineProperties(Constructor, staticProps); return Constructor; } function _createSuper(Derived) { return function () { var Super = _getPrototypeOf(Derived), result; if (_isNativeReflectConstruct()) { var NewTarget = _getPrototypeOf(this).constructor; result = Reflect.construct(Super, arguments, NewTarget); } else { result = Super.apply(this, arguments); } return _possibleConstructorReturn(this, result); }; } function _possibleConstructorReturn(self, call) { if (call && (_typeof(call) === "object" || typeof call === "function")) { return call; } return _assertThisInitialized(self); } function _assertThisInitialized(self) { if (self === void 0) { throw new ReferenceError("this hasn't been initialised - super() hasn't been called"); } return self; } function _isNativeReflectConstruct() { if (typeof Reflect === "undefined" || !Reflect.construct) return false; if (Reflect.construct.sham) return false; if (typeof Proxy === "function") return true; try { Date.prototype.toString.call(Reflect.construct(Date, [], function () {})); return true; } catch (e) { return false; } } function _getPrototypeOf(o) { _getPrototypeOf = Object.setPrototypeOf ? Object.getPrototypeOf : function _getPrototypeOf(o) { return o.__proto__ || Object.getPrototypeOf(o); }; return _getPrototypeOf(o); } function _inherits(subClass, superClass) { if (typeof superClass !== "function" && superClass !== null) { throw new TypeError("Super expression must either be null or a function"); } subClass.prototype = Object.create(superClass && superClass.prototype, { constructor: { value: subClass, writable: true, configurable: true } }); if (superClass) _setPrototypeOf(subClass, superClass); } function _setPrototypeOf(o, p) { _setPrototypeOf = Object.setPrototypeOf || function _setPrototypeOf(o, p) { o.__proto__ = p; return o; }; return _setPrototypeOf(o, p); } function _defineProperty(obj, key, value) { if (key in obj) { Object.defineProperty(obj, key, { value: value, enumerable: true, configurable: true, writable: true }); } else { obj[key] = value; } return obj; } var $ = require("jquery"); var SiteBarPlotExample = /*#__PURE__*/function (_Component) { _inherits(SiteBarPlotExample, _Component); var _super = _createSuper(SiteBarPlotExample); function SiteBarPlotExample(props) { var _this; _classCallCheck(this, SiteBarPlotExample); _this = _super.call(this, props); _defineProperty(_assertThisInitialized(_this), "getSiteNucleotideData", function (sequence_data) { (0, _nucleotideComposition.siteComposition)(sequence_data, _this.setSiteNucleotideDataToState); }); _defineProperty(_assertThisInitialized(_this), "setSiteNucleotideDataToState", function (siteNucleotideData) { _this.setState({ siteNucleotideData: siteNucleotideData }); }); _defineProperty(_assertThisInitialized(_this), "switchNucleotide", function (nucleotide) { _this.setState({ nucleotideInView: nucleotide }); }); _this.label_width = 200; _this.state = { nucleotideInView: "A", siteNucleotideData: null }; _this.initialize(_this.props); return _this; } _createClass(SiteBarPlotExample, [{ key: "componentDidMount", value: function componentDidMount() { this.getSiteNucleotideData(this.sequence_data); } }, { key: "componentWillUpdate", value: function componentWillUpdate(nextProps, prevState) { //TODO: replace componentWillUpdate as this is deprecated in future versions of react. this.setScrollingEvents(nextProps); } }, { key: "componentDidUpdate", value: function componentDidUpdate(prevProps, prevState) { if (this.state.siteNucleotideData == null) { this.getSiteNucleotideData(this.sequence_data); } } }, { key: "setScrollingEvents", value: function setScrollingEvents(props) { var _this2 = this; if (props.fasta) { var width = props.width, height = props.height, axis_height = props.axis_height; this.scroll_broadcaster = new _ScrollBroadcaster["default"]({ width: this.full_pixel_width, height: this.full_pixel_height, x_pad: width - this.label_width, y_pad: height - axis_height, x_pixel: this.x_pixel, y_pixel: this.y_pixel, bidirectional: ["alignmentjs-siteBarPlot-div", "alignmentjs-alignment", "alignmentjs-axis-div", "alignmentjs-labels-div"] }); // Update this.x_pixel on scroll events so that the alignment and plots will render to the correct scroll location on re-renders. document.getElementById("alignmentjs-alignment").addEventListener("alignmentjs_wheel_event", function (e) { _this2.x_pixel = e.detail.x_pixel; }); } } }, { key: "initialize", value: function initialize(props) { if (props.fasta) { var fasta = props.fasta, site_size = props.site_size, width = props.width, height = props.height; this.sequence_data = (0, _fasta["default"])(props.fasta); var sequence_data = this.sequence_data; var label_padding = this.props.label_padding; this.label_width = (0, _computeLabelWidth["default"])(sequence_data, label_padding); this.full_pixel_width = site_size * sequence_data.number_of_sites; this.full_pixel_height = site_size * sequence_data.number_of_sequences; var centerOnSite = props.centerOnSite, centerOnHeader = props.centerOnHeader; this.x_pixel = site_size * centerOnSite - width / 2 || 0; this.y_pixel = centerOnHeader ? site_size * this.sequence_data.map(function (record) { return record.header; }).indexOf(centerOnHeader) - height / 2 : 0; } this.setScrollingEvents(props); } }, { key: "render", value: function render() { var full_pixel_width = this.full_pixel_width, full_pixel_height = this.full_pixel_height, label_width = this.label_width, width = full_pixel_width ? Math.min(label_width + full_pixel_width, this.props.width) : this.props.width, height = full_pixel_height ? Math.min(full_pixel_height + this.props.axis_height, this.props.height) : this.props.height; var barPlotHeight = 120; var bar_plot_data = this.state.siteNucleotideData == null ? null : this.state.siteNucleotideData[this.state.nucleotideInView]; return /*#__PURE__*/_react["default"].createElement("div", null, /*#__PURE__*/_react["default"].createElement(SwitchNucleotideButtons, { switchNucleotide: this.switchNucleotide }), /*#__PURE__*/_react["default"].createElement("div", { id: "alignmentjs-main-div", style: { width: width, height: height } }, /*#__PURE__*/_react["default"].createElement(_SitePlotAxis["default"], { label_width: this.label_width, data: bar_plot_data, height: barPlotHeight, max_value: 1, axis_label: "Nucleotide %", scroll_broadcaster: this.scroll_broadcaster }), /*#__PURE__*/_react["default"].createElement(_BaseSiteBarPlot["default"], { data: bar_plot_data, siteSize: this.props.site_size, width: full_pixel_width, height: barPlotHeight, fillColor: this.props.site_color(this.state.nucleotideInView), outlineColor: this.props.text_color(this.state.nucleotideInView), x_pixel: this.x_pixel, max_value: 1, scroll_broadcaster: this.scroll_broadcaster }), /*#__PURE__*/_react["default"].createElement(_Placeholder["default"], { width: this.label_width, height: this.props.axis_height }), /*#__PURE__*/_react["default"].createElement(_SiteAxis["default"], { height: this.props.axis_height, site_size: this.props.site_size, sequence_data: this.sequence_data, x_pixel: this.x_pixel, scroll_broadcaster: this.scroll_broadcaster }), /*#__PURE__*/_react["default"].createElement(_SequenceAxis["default"], { width: this.label_width, height: height - this.props.axis_height, sequence_data: this.sequence_data, site_size: this.props.site_size, y_pixel: this.y_pixel, scroll_broadcaster: this.scroll_broadcaster }), /*#__PURE__*/_react["default"].createElement(_BaseAlignment["default"], { width: width - this.label_width, height: height - this.props.axis_height, sequence_data: this.sequence_data, site_color: this.props.site_color, text_color: this.props.text_color, site_size: this.props.site_size, x_pixel: this.x_pixel, y_pixel: this.y_pixel, scroll_broadcaster: this.scroll_broadcaster }))); } }]); return SiteBarPlotExample; }(_react.Component); SiteBarPlotExample.defaultProps = { site_color: _colors.nucleotide_color, text_color: _colors.nucleotide_text_color, label_padding: 10, site_size: 20, axis_height: 20, sender: "main" }; var SwitchNucleotideButtons = /*#__PURE__*/function (_React$Component) { _inherits(SwitchNucleotideButtons, _React$Component); var _super2 = _createSuper(SwitchNucleotideButtons); function SwitchNucleotideButtons(props) { _classCallCheck(this, SwitchNucleotideButtons); return _super2.call(this, props); } _createClass(SwitchNucleotideButtons, [{ key: "render", value: function render() { var _this3 = this; return /*#__PURE__*/_react["default"].createElement("div", { className: "btn-group btn-group-toggle", "data-toggle": "buttons" }, /*#__PURE__*/_react["default"].createElement("label", { className: "btn btn-light active", onClick: function onClick() { return _this3.props.switchNucleotide("A"); } }, /*#__PURE__*/_react["default"].createElement("input", { type: "radio" }), "A"), /*#__PURE__*/_react["default"].createElement("label", { className: "btn btn-light", onClick: function onClick() { return _this3.props.switchNucleotide("C"); } }, /*#__PURE__*/_react["default"].createElement("input", { type: "radio" }), "C"), /*#__PURE__*/_react["default"].createElement("label", { className: "btn btn-light", onClick: function onClick() { return _this3.props.switchNucleotide("G"); } }, /*#__PURE__*/_react["default"].createElement("input", { type: "radio" }), "G"), /*#__PURE__*/_react["default"].createElement("label", { className: "btn btn-light", onClick: function onClick() { return _this3.props.switchNucleotide("T"); } }, /*#__PURE__*/_react["default"].createElement("input", { type: "radio" }), "T")); } }]); return SwitchNucleotideButtons; }(_react["default"].Component); var _default = SiteBarPlotExample; exports["default"] = _default;