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@rcsb/rcsb-saguaro-app

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import { AnnotationReference } from "@rcsb/rcsb-api-tools/lib/RcsbGraphQL/Types/Borrego/GqlTypes"; import { cloneDeep } from "lodash"; import { FeatureType } from "../../RcsbExport/FeatureType"; export function buriedResidues(annotations) { var _a, _b; const accThr = 6; let buriedResidues = {}; let nBuried = 0; mainloop: for (const ann of annotations) { if (ann.source === AnnotationReference.PdbInstance) { for (const f of (_a = ann.features) !== null && _a !== void 0 ? _a : []) { if ((f === null || f === void 0 ? void 0 : f.type) === FeatureType.Asa) { buriedResidues = cloneDeep(ann); buriedResidues.source = AnnotationReference.PdbInstance; const feature = cloneDeep(f); feature.type = FeatureType.BuriedResidues; feature.name = "Unbound chain core residues"; feature.description = `Residue accessibility lower than ${accThr}Å`; (_b = feature.feature_positions) === null || _b === void 0 ? void 0 : _b.forEach(p => { var _a; if (p) p.values = (_a = p.values) === null || _a === void 0 ? void 0 : _a.map((v) => { if (v) { const acc = (v < accThr ? Math.floor(v * 100) / 100 : 0); nBuried += acc; return acc; } else { return 0; } }); }); buriedResidues.features = [feature]; break mainloop; } } } } return nBuried > 0 && buriedResidues ? [buriedResidues] : []; } export function buriedResiduesFilter(annotations) { return cloneDeep(annotations).map(ann => { var _a; ann.features = (_a = ann.features) === null || _a === void 0 ? void 0 : _a.filter(f => ((f === null || f === void 0 ? void 0 : f.type) !== FeatureType.Asa)); return ann; }).filter(ann => { var _a, _b; return (((_b = (_a = ann.features) === null || _a === void 0 ? void 0 : _a.length) !== null && _b !== void 0 ? _b : 0) > 0); }); } //# sourceMappingURL=BuriedResidues.js.map